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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2071469
log Bayes Factor = 138.522
Chromosome 6   position 32,784,783  (GRCh37) Explore rs2071469 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.003 0.997
E16 Other disorders of pancreatic internal secretion
0.000 0.005 0.995
E10.4 With neurological complications
0.000 0.006 0.994
E16.2 Hypoglycaemia, unspecified
0.000 0.008 0.992
E05.9 Thyrotoxicosis, unspecified
0.000 0.011 0.989
E14 Unspecified diabetes mellitus
0.000 0.019 0.981
E10.2 With renal complications
0.000 0.050 0.950
E10.8 With unspecified complications
0.000 0.053 0.947
E14.3 With ophthalmic complications
0.000 0.066 0.934
C44.7 Skin of lower limb, including hip
0.926 0.074 0.000
C44 Other malignant neoplasms of skin
0.916 0.084 0.000
C44.3 Skin of other and unspecified parts of face
0.903 0.097 0.000
E10.0 With coma
0.000 0.113 0.887
E10.6 With other specified complications
0.000 0.116 0.884
C44.2 Skin of ear and external auricular canal
0.868 0.132 0.000
L40.8 Other psoriasis
0.866 0.134 0.000
C44.4 Skin of scalp and neck
0.861 0.139 0.000
E40-E46 Malnutrition
0.000 0.140 0.860
J45 Asthma
0.000 0.154 0.846
E14.8 With unspecified complications
0.000 0.164 0.836
E07 Other disorders of thyroid
0.000 0.165 0.835
L40.4 Guttate psoriasis
0.829 0.171 0.000
L40.1 Generalised pustular psoriasis
0.821 0.179 0.000
L40.0 Psoriasis vulgaris
0.813 0.187 0.000
E10.5 With peripheral circulatory complications
0.000 0.188 0.812
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.194 0.806
J45.0 Predominantly allergic asthma
0.000 0.206 0.793
E14.2 Withrenal complications
0.000 0.207 0.793
E16.1 Other hypoglycaemia
0.000 0.225 0.775
E14.9 Without complications
0.000 0.228 0.772
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.229 0.771
E14.6 With other specified complications
0.000 0.235 0.765
E46 Unspecified protein-energy malnutrition
0.000 0.241 0.759
E07.9 Disorder of thyroid, unspecified
0.000 0.251 0.749
E14.5 With peripheral circulatory complications
0.000 0.273 0.727
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.287 0.713
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.287 0.713
E16.4 Abnormal secretion of gastrin
0.000 0.287 0.713
E16.3 Increased secretion of glucagon
0.000 0.287 0.713
E03.1 Congenital hypothyroidism without goitre
0.000 0.293 0.707
E14.7 With multiple complications
0.000 0.297 0.703
E14.0 With coma
0.000 0.297 0.703
E05.8 Other thyrotoxicosis
0.000 0.311 0.689
E03.8 Other specified hypothyroidism
0.000 0.311 0.689
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.317 0.683
J45.8 Mixed asthma
0.000 0.332 0.668
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.667 0.333 0.000
E14.1 With ketoacidosis
0.000 0.335 0.665
C44.9 Malignant neoplasm of skin, unspecified
0.661 0.339 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.340 0.660
C44.0 Skin of lip
0.658 0.342 0.000
C44.8 Overlapping lesion of skin
0.657 0.343 0.000
L40.3 Pustulosis palmaris et plantaris
0.653 0.347 0.000
J45.1 Nonallergic asthma
0.000 0.347 0.652
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.640 0.360 0.000
K90 Intestinal malabsorption
0.000 0.380 0.620
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.383 0.616
E45 Retarded development following protein-energy malnutrition
0.000 0.383 0.616
E43 Unspecified severe protein-energy malnutrition
0.000 0.383 0.616
E42 Marasmic kwashiorkor
0.000 0.383 0.616
E41 Nutritional marasmus
0.000 0.383 0.616
E40 Kwashiorkor
0.000 0.383 0.616
C82.0 Small cleaved cell, follicular
0.616 0.384 0.000
E14.4 With neurological complications
0.000 0.397 0.603
E07.1 Dyshormogenetic goitre
0.000 0.401 0.599
E07.0 Hypersecretion of calcitonin
0.000 0.401 0.599
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.545 0.455 0.000
C44.5 Skin of trunk
0.525 0.475 0.000
C82.2 Large cell, follicular
0.519 0.480 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.483 0.517
K90.9 Intestinal malabsorption, unspecified
0.000 0.483 0.517
E07.8 Other specified disorders of thyroid
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
C82.3 Follicular lymphoma grade IIIa
0.506 0.494 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.510 0.490
E13 Other specified diabetes mellitus
0.000 0.510 0.490
E06 Thyroiditis
0.000 0.530 0.470
E50-E64 Other nutritional deficiencies
0.000 0.536 0.464
C82.6 Cutaneous follicle centre lymphoma
0.459 0.541 0.000
C82.5 Diffuse follicle centre lymphoma
0.459 0.541 0.000
C82.4 Follicular lymphoma grade IIIb
0.447 0.552 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.555 0.445
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.555 0.445
K90.1 Tropical sprue
0.000 0.555 0.445
C82.1 Mixed small cleaved and large cell, follicular
0.444 0.556 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.443 0.557 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.558 0.442
E44.0 Moderate protein-energy malnutrition
0.000 0.558 0.442
K90.8 Other intestinal malabsorption
0.000 0.617 0.383
E13.8 With unspecified complications
0.000 0.649 0.351
E13.7 With multiple complications
0.000 0.649 0.351
E13.6 With other specified complications
0.000 0.649 0.351
E13.5 With peripheral circulatory complications
0.000 0.649 0.351
E13.4 With neurological complications
0.000 0.649 0.351
E13.2 With renal complications
0.000 0.649 0.351
E13.1 With ketoacidosis
0.000 0.649 0.351
E13.0 With coma
0.000 0.649 0.351
E67 Other hyperalimentation
0.000 0.649 0.351
E68 Sequelae of hyperalimentation
0.000 0.649 0.351
L40-L45 Papulosquamous disorders
0.343 0.657 0.000
C44.6 Skin of upper limb, including shoulder
0.343 0.657 0.000
E56 Other vitamin deficiencies
0.000 0.663 0.337
E06.4 Drug-induced thyroiditis
0.000 0.663 0.337
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.663 0.337
E06.1 Subacute thyroiditis
0.000 0.663 0.337
E06.0 Acute thyroiditis
0.000 0.663 0.337
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.667 0.333
E63 Other nutritional deficiencies
0.000 0.667 0.333
E50 Vitamin A deficiency
0.000 0.667 0.333
E60 Dietary zinc deficiency
0.000 0.667 0.333
E59 Dietary selenium deficiency
0.000 0.667 0.333
E54 Ascorbic acid deficiency
0.000 0.667 0.333
E52 Niacin deficiency [pellagra]
0.000 0.667 0.333
E06.5 Other chronic thyroiditis
0.000 0.670 0.330
E13.3 With ophthalmic complications
0.000 0.678 0.321
E51 Thiamine deficiency
0.000 0.682 0.318
E58 Dietary calcium deficiency
0.000 0.683 0.317
E66 Obesity
0.000 0.684 0.316
C43 Malignant melanoma of skin
0.314 0.686 0.000
C44.1 Skin of eyelid, including canthus
0.302 0.698 0.000
E53 Deficiency of other B group vitamins
0.000 0.705 0.295
E61 Deficiency of other nutrient elements
0.000 0.708 0.292
E66.8 Other obesity
0.000 0.721 0.279
E55 Vitamin D deficiency
0.000 0.725 0.275
E06.9 Thyroiditis, unspecified
0.000 0.734 0.265
C43.4 Malignant melanoma of scalp and neck
0.263 0.737 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.262 0.738 0.000
L41 Parapsoriasis
0.260 0.740 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.741 0.259
E67.8 Other specified hyperalimentation
0.000 0.748 0.252
E67.3 Hypervitaminosis D
0.000 0.748 0.252
E67.2 Megavitamin-B6 syndrome
0.000 0.748 0.252
E67.1 Hypercarotenaemia
0.000 0.748 0.252
E67.0 Hypervitaminosis A
0.000 0.748 0.252
E56.1 Deficiency of vitamin K
0.000 0.753 0.246
L44 Other papulosquamous disorders
0.246 0.754 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.246 0.754 0.000
C43.9 Malignant melanoma of skin, unspecified
0.244 0.756 0.000
L42 Pityriasis rosea
0.243 0.756 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.758 0.242
E56.8 Deficiency of other vitamins
0.000 0.758 0.242
E56.0 Deficiency of vitamin E
0.000 0.758 0.242
E50.9 Vitamin A deficiency, unspecified
0.000 0.761 0.238
E50.8 Other manifestations of vitamin A deficiency
0.000 0.761 0.238
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.761 0.238
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.761 0.238
E50.5 Vitamin A deficiency with night blindness
0.000 0.761 0.238
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.761 0.238
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.761 0.238
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.761 0.238
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.761 0.238
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.761 0.238
E63.9 Nutritional deficiency, unspecified
0.000 0.761 0.238
E63.8 Other specified nutritional deficiencies
0.000 0.761 0.238
E63.1 Imbalance of constituents of food intake
0.000 0.761 0.238
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.761 0.238
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.761 0.238
E64.8 Sequelae of other nutritional deficiencies
0.000 0.761 0.238
E64.3 Sequelae of rickets
0.000 0.761 0.238
E64.2 Sequelae of vitamin C deficiency
0.000 0.761 0.238
E64.1 Sequelae of vitamin A deficiency
0.000 0.761 0.238
E64.0 Sequelae of protein-energy malnutrition
0.000 0.761 0.238
E06.3 Autoimmune thyroiditis
0.000 0.765 0.235
C43.6 Malignant melanoma of upper limb, including shoulder
0.235 0.765 0.000
E11.1 With ketoacidosis
0.000 0.765 0.235
E51.9 Thiamine deficiency, unspecified
0.000 0.772 0.228
E51.8 Other manifestations of thiamine deficiency
0.000 0.772 0.228
E51.1 Beriberi
0.000 0.772 0.228
E66.1 Drug-induced obesity
0.000 0.773 0.227
C43.8 Overlapping malignant melanoma of skin
0.225 0.775 0.000
C43.0 Malignant melanoma of lip
0.225 0.775 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.220 0.780 0.000
E51.2 Wernicke's encephalopathy
0.000 0.787 0.213
E53.1 Pyridoxine deficiency
0.000 0.789 0.211
E53.0 Riboflavin deficiency
0.000 0.789 0.211
C43.2 Malignant melanoma of ear and external auricular canal
0.210 0.790 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.790 0.209
E61.8 Deficiency of other specified nutrient elements
0.000 0.790 0.209
E61.7 Deficiency of multiple nutrient elements
0.000 0.790 0.209
E61.6 Vanadium deficiency
0.000 0.790 0.209
E61.5 Molybdenum deficiency
0.000 0.790 0.209
E61.4 Chromium deficiency
0.000 0.790 0.209
E61.3 Manganese deficiency
0.000 0.790 0.209
E61.0 Copper deficiency
0.000 0.790 0.209
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.793 0.207
E61.2 Magnesium deficiency
0.000 0.793 0.206
E53.9 Vitamin B deficiency, unspecified
0.000 0.794 0.206
E11.4 With neurological complications
0.000 0.795 0.205
C43.1 Malignant melanoma of eyelid, including canthus
0.203 0.796 0.000
L41.1 Pityriasis lichenoides chronica
0.200 0.800 0.000
E65 Localised adiposity
0.001 0.802 0.197
E55.0 Rickets, active
0.000 0.803 0.197
E66.0 Obesity due to excess calories
0.000 0.804 0.196
E13.9 Without complications
0.001 0.812 0.188
L41.9 Parapsoriasis, unspecified
0.186 0.813 0.000
L41.8 Other parapsoriasis
0.186 0.813 0.000
L41.5 Retiform parapsoriasis
0.186 0.813 0.000
L41.4 Large plaque parapsoriasis
0.186 0.813 0.000
L41.3 Small plaque parapsoriasis
0.186 0.813 0.000
L41.2 Lymphomatoid papulosis
0.186 0.813 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.186 0.813 0.000
E11.7 With multiple complications
0.000 0.814 0.186
L43 Lichen planus
0.183 0.817 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.820 0.180
E11.3 With ophthalmic complications
0.000 0.822 0.178
L44.9 Papulosquamous disorder, unspecified
0.177 0.823 0.000
L44.8 Other specified papulosquamous disorders
0.177 0.823 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.177 0.823 0.000
L44.3 Lichen ruber moniliformis
0.177 0.823 0.000
L44.2 Lichen striatus
0.177 0.823 0.000
L44.1 Lichen nitidus
0.177 0.823 0.000
L44.0 Pityriasis rubra pilaris
0.177 0.823 0.000
E11.5 With peripheral circulatory complications
0.000 0.825 0.175
E11.6 With other specified complications
0.000 0.826 0.174
E61.1 Iron deficiency
0.000 0.827 0.173
E11.0 With coma
0.000 0.833 0.167
H36.0 Diabetic retinopathy
0.000 0.846 0.154
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.153 0.847 0.000
E66.9 Obesity, unspecified
0.000 0.860 0.140
E55.9 Vitamin D deficiency, unspecified
0.000 0.861 0.139
C90 Multiple myeloma and malignant plasma cell neoplasms
0.137 0.863 0.000
L43.3 Subacute (active) lichen planus
0.131 0.869 0.000
L43.2 Lichenoid drug reaction
0.131 0.869 0.000
L43.1 Bullous lichen planus
0.131 0.869 0.000
L43.0 Hypertrophic lichen planus
0.131 0.869 0.000
L43.8 Other lichen planus
0.130 0.870 0.000
E11.8 With unspecified complications
0.000 0.870 0.130
C73 Malignant neoplasm of thyroid gland
0.124 0.876 0.000
C93 Monocytic leukaemia
0.120 0.880 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.120 0.880 0.000
C95 Leukaemia of unspecified cell type
0.119 0.881 0.000
C90.0 Multiple myeloma
0.119 0.881 0.000
Chapter II Neoplasms
0.115 0.885 0.000
C86 Other specified types of T/NK-cell lymphoma
0.113 0.887 0.000
M07.3 Other psoriatic arthropathies
0.111 0.889 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.110 0.890 0.000
C94 Other leukaemias of specified cell type
0.110 0.890 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.108 0.892 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.106 0.894 0.000
C90.3 Solitary plasmacytoma
0.105 0.895 0.000
C90.2 Plasmacytoma, extramedullary
0.105 0.895 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.896 0.104
C84 Peripheral and cutaneous T-cell lymphomas
0.101 0.899 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.101 0.899 0.000
C90.1 Plasma cell leukaemia
0.100 0.900 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.099 0.901 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.098 0.902 0.000
C93.1 Chronic monocytic leukaemia
0.097 0.903 0.000
C74 Malignant neoplasm of adrenal gland
0.097 0.903 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.096 0.904 0.000
C95.0 Acute leukaemia of unspecified cell type
0.096 0.904 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.095 0.905 0.000
C02.9 Tongue, unspecified
0.088 0.911 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.088 0.912 0.000
C95.9 Leukaemia, unspecified
0.087 0.913 0.000
C93.9 Monocytic leukaemia, unspecified
0.086 0.913 0.000
C93.7 Other monocytic leukaemia
0.086 0.913 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.086 0.913 0.000
C93.2 Subacute monocytic leukaemia
0.086 0.913 0.000
C93.0 Acute monocytic leukaemia
0.086 0.913 0.000
C95.7 Other leukaemia of unspecified cell type
0.086 0.914 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.086 0.914 0.000
C02.1 Border of tongue
0.086 0.914 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.914 0.086
C86.5 Angioimmunoblastic T-cell lymphoma
0.085 0.915 0.000
C03 Malignant neoplasm of gum
0.085 0.915 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.085 0.915 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.084 0.916 0.000
C12 Malignant neoplasm of pyriform sinus
0.084 0.916 0.000
C00 Malignant neoplasm of lip
0.084 0.916 0.000
C81 Hodgkin's disease
0.083 0.917 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.082 0.917 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.082 0.918 0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.081 0.918 0.000
C86.4 Blastic NK-cell lymphoma
0.081 0.918 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.081 0.918 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.081 0.918 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.081 0.918 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.081 0.918 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.081 0.919 0.000
C88 Malignant immunoproliferative diseases
0.080 0.920 0.000
M07.38 Other psoriatic arthropathies (Other)
0.080 0.920 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.080 0.920 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.080 0.920 0.000
C94.7 Other specified leukaemias
0.079 0.921 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.079 0.921 0.000
C94.5 Acute myelofibrosis
0.079 0.921 0.000
C94.4 Acute panmyelosis
0.079 0.921 0.000
C94.3 Mast cell leukaemia
0.079 0.921 0.000
C94.2 Acute megakaryoblastic leukaemia
0.079 0.921 0.000
C94.1 Chronic erythraemia
0.079 0.921 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.079 0.921 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.079 0.921 0.000
C96.8 Histiocytic sarcoma
0.079 0.921 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.079 0.921 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.079 0.921 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.079 0.921 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.079 0.921 0.000
C96.3 True histiocytic lymphoma
0.079 0.921 0.000
C96.2 Malignant mast cell tumour
0.079 0.921 0.000
C96.1 Malignant histiocytosis
0.079 0.921 0.000
C96.0 Letterer-Siwe disease
0.079 0.921 0.000
C74.0 Cortex of adrenal gland
0.079 0.921 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.079 0.921 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.078 0.922 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.075 0.925 0.000
C84.5 Other and unspecified T-cell lymphomas
0.075 0.925 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.074 0.926 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.074 0.926 0.000
C13 Malignant neoplasm of hypopharynx
0.073 0.926 0.000
C05 Malignant neoplasm of palate
0.073 0.927 0.000
E11.2 With renal complications
0.000 0.927 0.073
C11 Malignant neoplasm of nasopharynx
0.073 0.927 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.072 0.927 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.072 0.927 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.072 0.927 0.000
C84.3 Lymphoepithelioid lymphoma
0.072 0.927 0.000
C84.2 T-zone lymphoma
0.072 0.927 0.000
C84.1 Sezary's diease
0.072 0.927 0.000
C84.4 Peripheral T-cell lymphoma
0.072 0.927 0.000
C02.2 Ventral surface of tongue
0.072 0.928 0.000
D50-D53 Nutritional anaemias
0.000 0.928 0.072
C32 Malignant neoplasm of larynx
0.072 0.928 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.071 0.929 0.000
C74.9 Adrenal gland, unspecified
0.070 0.929 0.000
C91 Lymphoid leukaemia
0.064 0.930 0.006
L43.9 Lichen planus, unspecified
0.070 0.930 0.000
C74.1 Medulla of adrenal gland
0.069 0.930 0.000
C02.8 Overlapping lesion of tongue
0.069 0.931 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.069 0.931 0.000
C02.0 Dorsal surface of tongue
0.069 0.931 0.000
C00.1 External lower lip
0.069 0.931 0.000
D50 Iron deficiency anaemia
0.000 0.932 0.068
C03.0 Upper gum
0.068 0.932 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.932 0.068
C03.9 Gum, unspecified
0.067 0.932 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.933 0.067
C83.3 Large cell (diffuse)
0.067 0.933 0.000
C92 Myeloid leukaemia
0.067 0.933 0.000
C81.7 Other Hodgkin's disease
0.067 0.933 0.000
C04 Malignant neoplasm of floor of mouth
0.066 0.933 0.000
D50.9 Iron deficiency anaemia, unspecified
0.000 0.934 0.066
C00.9 Lip, unspecified
0.065 0.934 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.065 0.935 0.000
C75.0 Parathyroid gland
0.065 0.935 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.064 0.936 0.000
C75.1 Pituitary gland
0.063 0.937 0.000
C75.8 Pluriglandular involvement, unspecified
0.063 0.937 0.000
C75.5 Aortic body and other paraganglia
0.063 0.937 0.000
C75.4 Carotid body
0.063 0.937 0.000
C75.3 Pineal gland
0.063 0.937 0.000
C75.2 Craniopharyngeal duct
0.063 0.937 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.063 0.937 0.000
C33 Malignant neoplasm of trachea
0.063 0.937 0.000
C10 Malignant neoplasm of oropharynx
0.063 0.937 0.000
C03.1 Lower gum
0.063 0.937 0.000
C75.9 Endocrine gland, unspecified
0.062 0.937 0.000
C32.0 Glottis
0.062 0.938 0.000
C02.4 Lingual tonsil
0.062 0.938 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.062 0.938 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.938 0.061
D51.2 Transcobalamin II deficiency
0.000 0.938 0.061
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.938 0.061
C81.0 Lymphocytic predominance
0.061 0.939 0.000
C81.2 Mixed cellularity
0.061 0.939 0.000
C32.9 Larynx, unspecified
0.061 0.939 0.000
C00.8 Overlapping lesion of lip
0.060 0.939 0.000
C00.6 Commissure of lip
0.060 0.939 0.000
C00.5 Lip, unspecified, inner aspect
0.060 0.939 0.000
C00.4 Lower lip, inner aspect
0.060 0.939 0.000
C00.3 Upper lip, inner aspect
0.060 0.939 0.000
C00.2 External lip, unspecified
0.060 0.939 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.061 0.939 0.000
C00.0 External upper lip
0.060 0.939 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.060 0.940 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.059 0.940 0.000
C81.3 Lymphocytic depletion
0.059 0.940 0.000
C05.0 Hard palate
0.059 0.941 0.000
C85.1 B-cell lymphoma, unspecified
0.059 0.941 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.058 0.941 0.000
C07 Malignant neoplasm of parotid gland
0.058 0.942 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.058 0.942 0.000
C31 Malignant neoplasm of accessory sinuses
0.058 0.942 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.058 0.942 0.000
C84.0 Mycosis fungoides
0.058 0.942 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.058 0.942 0.000
C88.7 Other malignant immunoproliferative diseases
0.058 0.942 0.000
C88.3 Immunoproliferative small intestinal disease
0.058 0.942 0.000
C88.2 Gamma heavy chain disease
0.058 0.942 0.000
C88.1 Alpha heavy chain disease
0.058 0.942 0.000
C60-C63 Malignant neoplasms of male genital organs
0.057 0.943 0.000
C43.5 Malignant melanoma of trunk
0.057 0.943 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.057 0.943 0.000
D53 Other nutritional anaemias
0.000 0.943 0.057
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.056 0.944 0.000
C85.0 Lymphosarcoma
0.056 0.944 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.056 0.944 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.056 0.944 0.000
C37 Malignant neoplasm of thymus
0.055 0.945 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.055 0.945 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.945 0.054
C08.0 Submandibular gland
0.054 0.945 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.054 0.946 0.000
C83.6 Undifferentiated (diffuse)
0.054 0.946 0.000
C83.5 Lymphoblastic (diffuse)
0.054 0.946 0.000
C83.4 Immunoblastic (diffuse)
0.054 0.946 0.000
C83.2 Mixed small and large cell (diffuse)
0.054 0.946 0.000
C91.0 Acute lymphoblastic leukaemia
0.051 0.946 0.003
C13.0 Postcricoid region
0.054 0.946 0.000
C06.0 Cheek mucosa
0.053 0.947 0.000
C13.9 Hypopharynx, unspecified
0.053 0.947 0.000
C08.8 Overlapping lesion of major salivary glands
0.053 0.947 0.000
C08.1 Sublingual gland
0.053 0.947 0.000
D43.2 Brain, unspecified
0.053 0.947 0.000
C13.8 Overlapping lesion of hypopharynx
0.053 0.947 0.000
C13.2 Posterior wall of hypopharynx
0.053 0.947 0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.053 0.947 0.000
C08.9 Major salivary gland, unspecified
0.053 0.947 0.000
D52 Folate deficiency anaemia
0.000 0.947 0.053
C91.5 Adult T-cell leukaemia
0.049 0.947 0.004
C05.8 Overlapping lesion of palate
0.053 0.947 0.000
C05.2 Uvula
0.053 0.947 0.000
C11.9 Nasopharynx, unspecified
0.053 0.947 0.000
E04 Other non-toxic goitre
0.001 0.947 0.052
C11.8 Overlapping lesion of nasopharynx
0.052 0.948 0.000
C11.3 Anterior wall of nasopharynx
0.052 0.948 0.000
C11.2 Lateral wall of nasopharynx
0.052 0.948 0.000
C11.1 Posterior wall of nasopharynx
0.052 0.948 0.000
C11.0 Superior wall of nasopharynx
0.052 0.948 0.000
C32.8 Overlapping lesion of larynx
0.052 0.948 0.000
C32.3 Laryngeal cartilage
0.052 0.948 0.000
C32.2 Subglottis
0.052 0.948 0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.051 0.949 0.000
C06.1 Vestibule of mouth
0.051 0.949 0.000
C06.9 Mouth, unspecified
0.051 0.949 0.000
C09 Malignant neoplasm of tonsil
0.051 0.949 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.050 0.949 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.046 0.949 0.004
C91.7 Other lymphoid leukaemia
0.046 0.949 0.004
C91.6 Prolymphocytic leukaemia of T-cell type
0.046 0.949 0.004
C91.3 Prolymphocytic leukaemia
0.046 0.949 0.004
C91.2 Subacute lymphocytic leukaemia
0.046 0.949 0.004
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.050 0.950 0.000
D43.0 Brain, supratentorial
0.050 0.950 0.000
C92.9 Myeloid leukaemia, unspecified
0.049 0.951 0.000
D40.1 Testis
0.049 0.951 0.000
D50.1 Sideropenic dysphagia
0.000 0.951 0.049
C05.9 Palate, unspecified
0.049 0.951 0.000
C05.1 Soft palate
0.048 0.951 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.951 0.048
C92.7 Other myeloid leukaemia
0.048 0.951 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.951 0.049
C50-C50 Malignant neoplasm of breast
0.048 0.952 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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