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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2074512
log Bayes Factor = 74.7936
Chromosome 6   position 30,878,919  (GRCh37) Explore rs2074512 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.002 0.998
L40.0 Psoriasis vulgaris
0.997 0.003 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.003 0.997
E10.9 Without complications
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.019 0.981
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.019 0.981
E10.4 With neurological complications
0.000 0.042 0.958
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.069 0.931
M07.3 Other psoriatic arthropathies
0.920 0.080 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.919 0.081 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.915 0.085 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.105 0.895
E10.5 With peripheral circulatory complications
0.000 0.107 0.893
E10.3 With ophthalmic complications
0.000 0.107 0.893
L40.8 Other psoriasis
0.892 0.108 0.000
E07 Other disorders of thyroid
0.000 0.121 0.879
E16.2 Hypoglycaemia, unspecified
0.000 0.129 0.871
E10.1 With ketoacidosis
0.000 0.132 0.868
L40.1 Generalised pustular psoriasis
0.855 0.145 0.000
E10.6 With other specified complications
0.000 0.169 0.831
E07.9 Disorder of thyroid, unspecified
0.000 0.170 0.830
E10.2 With renal complications
0.000 0.189 0.811
E10.0 With coma
0.000 0.191 0.809
M07.34 Other psoriatic arthropathies (Hand)
0.808 0.192 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.200 0.800
M07.36 Other psoriatic arthropathies (Lower leg)
0.785 0.215 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.765 0.235 0.000
E06 Thyroiditis
0.000 0.235 0.765
E50-E64 Other nutritional deficiencies
0.000 0.247 0.753
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.249 0.751
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.268 0.732
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.285 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.296 0.704
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.300 0.700
E15 Nondiabetic hypoglycaemic coma
0.000 0.332 0.667
M07.38 Other psoriatic arthropathies (Other)
0.659 0.341 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.659 0.341 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.659 0.341 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.659 0.341 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.659 0.341 0.000
E03.8 Other specified hypothyroidism
0.000 0.349 0.651
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.358 0.642
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.358 0.642
E16.4 Abnormal secretion of gastrin
0.000 0.358 0.642
E16.3 Increased secretion of glucagon
0.000 0.358 0.642
E07.1 Dyshormogenetic goitre
0.000 0.370 0.630
E07.0 Hypersecretion of calcitonin
0.000 0.370 0.630
E55 Vitamin D deficiency
0.000 0.387 0.613
E06.3 Autoimmune thyroiditis
0.000 0.408 0.592
E13 Other specified diabetes mellitus
0.000 0.443 0.556
E06.9 Thyroiditis, unspecified
0.000 0.447 0.553
E10.8 With unspecified complications
0.000 0.450 0.550
E16.1 Other hypoglycaemia
0.000 0.450 0.549
E06.5 Other chronic thyroiditis
0.000 0.452 0.548
E06.4 Drug-induced thyroiditis
0.000 0.452 0.548
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.452 0.548
E06.1 Subacute thyroiditis
0.000 0.452 0.548
E06.0 Acute thyroiditis
0.000 0.452 0.548
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.460 0.540
E63 Other nutritional deficiencies
0.000 0.460 0.540
E56 Other vitamin deficiencies
0.000 0.460 0.540
E51 Thiamine deficiency
0.000 0.460 0.540
E50 Vitamin A deficiency
0.000 0.460 0.540
E60 Dietary zinc deficiency
0.000 0.460 0.540
E59 Dietary selenium deficiency
0.000 0.460 0.540
E58 Dietary calcium deficiency
0.000 0.460 0.540
E54 Ascorbic acid deficiency
0.000 0.460 0.540
E52 Niacin deficiency [pellagra]
0.000 0.460 0.540
E65-E68 Obesity and other hyperalimentation
0.000 0.465 0.535
E53 Deficiency of other B group vitamins
0.000 0.476 0.524
E61 Deficiency of other nutrient elements
0.000 0.478 0.522
K90 Intestinal malabsorption
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E55.9 Vitamin D deficiency, unspecified
0.000 0.487 0.513
E12.9 Without complications
0.000 0.495 0.504
E12.8 With unspecified complications
0.000 0.495 0.504
E12.7 With multiple complications
0.000 0.495 0.504
E12.6 With other specified complications
0.000 0.495 0.504
E12.5 With peripheral circulatory complications
0.000 0.495 0.504
E12.4 With neurological complications
0.000 0.495 0.504
E12.3 With ophthalmic complications
0.000 0.495 0.504
E12.2 With renal complications
0.000 0.495 0.504
E12.1 With ketoacidosis
0.000 0.495 0.504
E12.0 With coma
0.000 0.495 0.504
E40-E46 Malnutrition
0.001 0.515 0.485
E14 Unspecified diabetes mellitus
0.000 0.538 0.462
E04 Other non-toxic goitre
0.000 0.538 0.462
E07.8 Other specified disorders of thyroid
0.000 0.557 0.443
E55.0 Rickets, active
0.000 0.560 0.440
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.568 0.432
K90.9 Intestinal malabsorption, unspecified
0.000 0.594 0.406
E14.3 With ophthalmic complications
0.000 0.595 0.405
M07 Psoriatic and enteropathic arthropathies
0.403 0.597 0.000
E13.8 With unspecified complications
0.000 0.601 0.399
E13.7 With multiple complications
0.000 0.601 0.399
E13.6 With other specified complications
0.000 0.601 0.399
E13.5 With peripheral circulatory complications
0.000 0.601 0.399
E13.4 With neurological complications
0.000 0.601 0.399
E13.3 With ophthalmic complications
0.000 0.601 0.399
E13.2 With renal complications
0.000 0.601 0.399
E13.1 With ketoacidosis
0.000 0.601 0.399
E13.0 With coma
0.000 0.601 0.399
E53.9 Vitamin B deficiency, unspecified
0.000 0.602 0.398
E50.9 Vitamin A deficiency, unspecified
0.000 0.613 0.387
E50.8 Other manifestations of vitamin A deficiency
0.000 0.613 0.387
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.613 0.387
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.613 0.387
E50.5 Vitamin A deficiency with night blindness
0.000 0.613 0.387
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.613 0.387
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.613 0.387
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.613 0.387
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.613 0.387
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.613 0.387
E51.9 Thiamine deficiency, unspecified
0.000 0.613 0.387
E51.8 Other manifestations of thiamine deficiency
0.000 0.613 0.387
E51.2 Wernicke's encephalopathy
0.000 0.613 0.387
E51.1 Beriberi
0.000 0.613 0.387
E56.9 Vitamin deficiency, unspecified
0.000 0.613 0.387
E56.8 Deficiency of other vitamins
0.000 0.613 0.387
E56.1 Deficiency of vitamin K
0.000 0.613 0.387
E56.0 Deficiency of vitamin E
0.000 0.613 0.387
E63.9 Nutritional deficiency, unspecified
0.000 0.613 0.387
E63.8 Other specified nutritional deficiencies
0.000 0.613 0.387
E63.1 Imbalance of constituents of food intake
0.000 0.613 0.387
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.613 0.387
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.613 0.387
E64.8 Sequelae of other nutritional deficiencies
0.000 0.613 0.387
E64.3 Sequelae of rickets
0.000 0.613 0.387
E64.2 Sequelae of vitamin C deficiency
0.000 0.613 0.387
E64.1 Sequelae of vitamin A deficiency
0.000 0.613 0.387
E64.0 Sequelae of protein-energy malnutrition
0.000 0.613 0.387
E67 Other hyperalimentation
0.000 0.616 0.384
E68 Sequelae of hyperalimentation
0.000 0.616 0.384
E61.2 Magnesium deficiency
0.000 0.619 0.381
E04.9 Non-toxic goitre, unspecified
0.000 0.624 0.376
E53.1 Pyridoxine deficiency
0.000 0.624 0.375
E53.0 Riboflavin deficiency
0.000 0.624 0.375
E61.9 Deficiency of nutrient element, unspecified
0.000 0.626 0.374
E61.8 Deficiency of other specified nutrient elements
0.000 0.626 0.374
E61.7 Deficiency of multiple nutrient elements
0.000 0.626 0.374
E61.6 Vanadium deficiency
0.000 0.626 0.374
E61.5 Molybdenum deficiency
0.000 0.626 0.374
E61.4 Chromium deficiency
0.000 0.626 0.374
E61.3 Manganese deficiency
0.000 0.626 0.374
E61.0 Copper deficiency
0.000 0.626 0.374
K90.3 Pancreatic steatorrhoea
0.000 0.630 0.370
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.630 0.370
K90.1 Tropical sprue
0.000 0.630 0.370
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.652 0.347
E45 Retarded development following protein-energy malnutrition
0.001 0.652 0.347
E43 Unspecified severe protein-energy malnutrition
0.001 0.652 0.347
E42 Marasmic kwashiorkor
0.001 0.652 0.347
E41 Nutritional marasmus
0.001 0.652 0.347
E40 Kwashiorkor
0.001 0.652 0.347
E61.1 Iron deficiency
0.000 0.652 0.348
E14.7 With multiple complications
0.000 0.669 0.331
E14.6 With other specified complications
0.000 0.669 0.331
E14.2 Withrenal complications
0.000 0.669 0.331
E14.0 With coma
0.000 0.669 0.331
E04.8 Other specified non-toxic goitre
0.000 0.669 0.331
E53.8 Deficiency of other specified B group vitamins
0.000 0.671 0.329
E14.1 With ketoacidosis
0.000 0.675 0.325
E14.8 With unspecified complications
0.000 0.683 0.316
E65 Localised adiposity
0.000 0.685 0.315
E66 Obesity
0.000 0.685 0.315
E14.5 With peripheral circulatory complications
0.000 0.702 0.298
E66.8 Other obesity
0.000 0.707 0.293
M07.6 Other enteropathic arthropathies
0.289 0.711 0.000
M07.5 Arthropathy in ulcerative colitis
0.289 0.711 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.289 0.711 0.000
M07.2 Psoriatic spondylitis
0.289 0.711 0.000
M07.1 Arthritis mutilans
0.289 0.711 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.289 0.711 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.718 0.281
E67.8 Other specified hyperalimentation
0.000 0.725 0.275
E67.3 Hypervitaminosis D
0.000 0.725 0.275
E67.2 Megavitamin-B6 syndrome
0.000 0.725 0.275
E67.1 Hypercarotenaemia
0.000 0.725 0.275
E67.0 Hypervitaminosis A
0.000 0.725 0.275
E14.4 With neurological complications
0.000 0.733 0.267
E13.9 Without complications
0.001 0.748 0.252
K90.8 Other intestinal malabsorption
0.001 0.749 0.251
E44.1 Mild protein-energy malnutrition
0.001 0.750 0.249
E44.0 Moderate protein-energy malnutrition
0.001 0.750 0.249
E04.2 Non-toxic multinodular goitre
0.000 0.751 0.249
L40-L45 Papulosquamous disorders
0.228 0.772 0.000
E66.1 Drug-induced obesity
0.000 0.774 0.226
E20-E35 Disorders of other endocrine glands
0.000 0.777 0.223
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.207 0.792 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.207 0.792 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.207 0.792 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.207 0.792 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.207 0.792 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.207 0.792 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.207 0.792 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.207 0.792 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.207 0.792 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.207 0.792 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.207 0.792 0.000
M07.18 Arthritis mutilans (Other)
0.207 0.792 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.207 0.792 0.000
M07.16 Arthritis mutilans (Lower leg)
0.207 0.792 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.207 0.792 0.000
M07.14 Arthritis mutilans (Hand)
0.207 0.792 0.000
M07.13 Arthritis mutilans (Forearm)
0.207 0.792 0.000
M07.12 Arthritis mutilans (Upper arm)
0.207 0.792 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.207 0.792 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.207 0.792 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.207 0.792 0.000
M07.28 Psoriatic spondylitis (Other)
0.207 0.792 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.207 0.792 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.207 0.792 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.207 0.792 0.000
M07.24 Psoriatic spondylitis (Hand)
0.207 0.792 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.207 0.792 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.207 0.792 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.207 0.792 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.207 0.792 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.207 0.792 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.207 0.792 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.207 0.792 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.207 0.792 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.207 0.792 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.207 0.792 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.207 0.792 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.207 0.792 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.207 0.792 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.207 0.792 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.207 0.792 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.207 0.792 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.207 0.792 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.207 0.792 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.207 0.792 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.207 0.792 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.207 0.792 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.207 0.792 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.207 0.792 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.207 0.792 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.207 0.792 0.000
M07.68 Other enteropathic arthropathies (Other)
0.207 0.792 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.207 0.792 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.207 0.792 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.207 0.792 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.207 0.792 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.207 0.792 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.207 0.792 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.207 0.792 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.207 0.792 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.799 0.201
E27 Other disorders of adrenal gland
0.000 0.799 0.201
E27.1 Primary adrenocortical insufficiency
0.000 0.802 0.198
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.805 0.195
E66.0 Obesity due to excess calories
0.000 0.833 0.166
L44 Other papulosquamous disorders
0.164 0.836 0.000
L41 Parapsoriasis
0.164 0.836 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.164 0.836 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.840 0.160
E32 Diseases of thymus
0.000 0.840 0.160
E31 Polyglandular dysfunction
0.000 0.840 0.160
E30 Disorders of puberty, not elsewhere classified
0.000 0.840 0.160
E25 Adrenogenital disorders
0.000 0.840 0.160
L42 Pityriasis rosea
0.159 0.841 0.000
E34 Other endocrine disorders
0.000 0.843 0.157
E29 Testicular dysfunction
0.000 0.849 0.151
E20 Hypoparathyroidism
0.000 0.849 0.150
E27.8 Other specified disorders of adrenal gland
0.000 0.850 0.149
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.000 0.854 0.146
E27.5 Adrenomedullary hyperfunction
0.000 0.856 0.144
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.856 0.144
E27.0 Other adrenocortical overactivity
0.000 0.856 0.144
E26 Hyperaldosteronism
0.000 0.862 0.138
E22 Hyperfunction of pituitary gland
0.000 0.863 0.137
E24 Cushing's syndrome
0.000 0.864 0.136
E27.2 Addisonian crisis
0.000 0.865 0.135
E28 Ovarian dysfunction
0.000 0.869 0.131
E46 Unspecified protein-energy malnutrition
0.002 0.869 0.128
E34.9 Endocrine disorder, unspecified
0.000 0.877 0.123
L41.9 Parapsoriasis, unspecified
0.117 0.882 0.000
L41.8 Other parapsoriasis
0.117 0.882 0.000
L41.5 Retiform parapsoriasis
0.117 0.882 0.000
L41.4 Large plaque parapsoriasis
0.117 0.882 0.000
L41.3 Small plaque parapsoriasis
0.117 0.882 0.000
L41.2 Lymphomatoid papulosis
0.117 0.882 0.000
L41.1 Pityriasis lichenoides chronica
0.117 0.882 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.117 0.882 0.000
L44.9 Papulosquamous disorder, unspecified
0.117 0.882 0.000
L44.8 Other specified papulosquamous disorders
0.117 0.882 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.117 0.882 0.000
L44.3 Lichen ruber moniliformis
0.117 0.882 0.000
L44.2 Lichen striatus
0.117 0.882 0.000
L44.1 Lichen nitidus
0.117 0.882 0.000
L44.0 Pityriasis rubra pilaris
0.117 0.882 0.000
E34.0 Carcinoid syndrome
0.000 0.883 0.117
E25.9 Adrenogenital disorder, unspecified
0.000 0.885 0.115
E25.8 Other adrenogenital disorders
0.000 0.885 0.115
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.885 0.115
E30.9 Disorder of puberty, unspecified
0.000 0.885 0.115
E30.8 Other disorders of puberty
0.000 0.885 0.115
E30.1 Precocious puberty
0.000 0.885 0.115
E30.0 Delayed puberty
0.000 0.885 0.115
E31.9 Polyglandular dysfunction, unspecified
0.000 0.885 0.115
E31.8 Other polyglandular dysfunction
0.000 0.885 0.115
E31.1 Polyglandular hyperfunction
0.000 0.885 0.115
E31.0 Autoimmune polyglandular failure
0.000 0.885 0.115
E32.9 Disease of thymus, unspecified
0.000 0.885 0.115
E32.8 Other diseases of thymus
0.000 0.885 0.115
E32.1 Abscess of thymus
0.000 0.885 0.115
E32.0 Persistent hyperplasia of thymus
0.000 0.885 0.115
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.885 0.115
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.885 0.115
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.885 0.115
E34.5 Androgen resistance syndrome
0.000 0.887 0.112
E34.4 Constitutional tall stature
0.000 0.887 0.112
E34.3 Short stature, not elsewhere classified
0.000 0.887 0.112
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.887 0.112
E34.1 Other hypersecretion of intestinal hormones
0.000 0.887 0.112
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.109 0.891 0.000
E22.1 Hyperprolactinaemia
0.000 0.891 0.109
E29.9 Testicular dysfunction, unspecified
0.000 0.892 0.108
E29.8 Other testicular dysfunction
0.000 0.892 0.108
E29.0 Testicular hyperfunction
0.000 0.892 0.108
E20.8 Other hypoparathyroidism
0.000 0.892 0.108
E20.1 Pseudohypoparathyroidism
0.000 0.892 0.108
E20.0 Idiopathic hypoparathyroidism
0.000 0.892 0.108
T36-T50 Poisoning by drugs, medicaments and biological substances
0.107 0.893 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.107 0.893 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.106 0.894 0.000
T43.2 Other and unspecified antidepressants
0.100 0.900 0.000
E29.1 Testicular hypofunction
0.000 0.901 0.099
E26.9 Hyperaldosteronism, unspecified
0.000 0.901 0.099
E26.8 Other hyperaldosteronism
0.000 0.901 0.099
E26.1 Secondary hyperaldosteronism
0.000 0.901 0.099
E24.2 Drug-induced Cushing's syndrome
0.000 0.901 0.099
E20.9 Hypoparathyroidism, unspecified
0.000 0.901 0.099
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.901 0.099
E22.8 Other hyperfunction of pituitary gland
0.000 0.901 0.099
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.901 0.098
E27.9 Disorder of adrenal gland, unspecified
0.000 0.901 0.098
E24.8 Other Cushing's syndrome
0.000 0.902 0.098
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.902 0.098
E24.3 Ectopic ACTH syndrome
0.000 0.902 0.098
E24.1 Nelson's syndrome
0.000 0.902 0.098
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.098 0.902 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.906 0.094
E28.8 Other ovarian dysfunction
0.000 0.906 0.094
E28.1 Androgen excess
0.000 0.906 0.094
E28.0 Oestrogen excess
0.000 0.906 0.094
T43.0 Tricyclic and tetracyclic antidepressants
0.094 0.906 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.094 0.906 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.093 0.907 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.092 0.908 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.909 0.091
E28.3 Primary ovarian failure
0.000 0.909 0.091
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.089 0.911 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.912 0.088
E34.8 Other specified endocrine disorders
0.000 0.913 0.087
T43.6 Psychostimulants with abuse potential
0.087 0.913 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.914 0.086
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.086 0.914 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.085 0.915 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.916 0.084
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.916 0.084
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.084 0.916 0.000
L43 Lichen planus
0.082 0.917 0.001
T50.9 Other and unspecified drugs, medicaments and biological substances
0.082 0.918 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.082 0.918 0.000
T36 Poisoning by systemic antibiotics
0.081 0.919 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.080 0.920 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.078 0.921 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.078 0.921 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.078 0.921 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.078 0.921 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.078 0.921 0.000
T44.0 Anticholinesterase agents
0.078 0.921 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.078 0.922 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.077 0.923 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.077 0.923 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.077 0.923 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.077 0.923 0.000
T43.9 Psychotropic drug, unspecified
0.077 0.923 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.077 0.923 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.077 0.923 0.000
E26.0 Primary hyperaldosteronism
0.000 0.923 0.076
T47.4 Other laxatives
0.074 0.926 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.074 0.926 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.073 0.927 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.071 0.928 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.929 0.071
K90-K93 Other diseases of the digestive system
0.000 0.929 0.071
E14.9 Without complications
0.000 0.931 0.069
F33 Recurrent depressive disorder
0.069 0.931 0.000
Chapter V Mental and behavioural disorders
0.068 0.932 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.068 0.932 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.068 0.932 0.000
T47.7 Emetics
0.068 0.932 0.000
T47.6 Antidiarrhoeal drugs
0.068 0.932 0.000
T47.5 Digestants
0.068 0.932 0.000
T47.3 Saline and osmotic laxatives
0.068 0.932 0.000
T47.2 Stimulant laxatives
0.068 0.932 0.000
T47.0 Histamine H(2)-receptor antagonists
0.068 0.932 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.933 0.067
F30-F39 Mood [affective] disorders
0.067 0.933 0.000
F33.9 Recurrent depressive disorder, unspecified
0.067 0.933 0.000
T50.8 Diagnostic agents
0.066 0.933 0.000
T50.7 Analeptics and opioid receptor antagonists
0.066 0.933 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.066 0.933 0.000
T50.5 Appetite depressants
0.066 0.933 0.000
T50.4 Drugs affecting uric acid metabolism
0.066 0.933 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.066 0.933 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.066 0.933 0.000
T50.1 Loop [high-ceiling] diuretics
0.066 0.933 0.000
T50.0 Mineralocorticoids and their antagonists
0.066 0.933 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.066 0.933 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.065 0.935 0.000
F60-F69 Disorders of adult personality and behaviour
0.064 0.936 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.064 0.936 0.000
T38.1 Thyroid hormones and substitutes
0.063 0.936 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.063 0.937 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.063 0.937 0.000
T36.0 Penicillins
0.063 0.937 0.000
F60 Specific personality disorders
0.062 0.938 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.062 0.938 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.062 0.938 0.000
T42.3 Barbiturates
0.062 0.938 0.000
T42.2 Succinimides and oxazolidinediones
0.062 0.938 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.061 0.939 0.000
T38.9 Other and unspecified hormone antagonists
0.061 0.939 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.061 0.939 0.000
T38.7 Androgens and anabolic congeners
0.061 0.939 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.061 0.939 0.000
T38.5 Other oestrogens and progestogens
0.061 0.939 0.000
T38.4 Oral contraceptives
0.061 0.939 0.000
T38.2 Antithyroid drugs
0.061 0.939 0.000
T38.0 Glucocorticoids and synthetic analogues
0.061 0.939 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.939 0.060
E23.1 Drug-induced hypopituitarism
0.000 0.939 0.060
T46.5 Other antihypertensive drugs, not elsewhere classified
0.060 0.939 0.000
F40 Phobic anxiety disorders
0.060 0.940 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.940 0.060
E21.2 Other hyperparathyroidism
0.000 0.940 0.060
T42.0 Hydantoin derivatives
0.060 0.940 0.000
L43.3 Subacute (active) lichen planus
0.059 0.940 0.001
L43.2 Lichenoid drug reaction
0.059 0.940 0.001
L43.1 Bullous lichen planus
0.059 0.940 0.001
L43.0 Hypertrophic lichen planus
0.059 0.940 0.001
F33.1 Recurrent depressive disorder, current episode moderate
0.060 0.940 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.059 0.941 0.000
T42.1 Iminostilbenes
0.059 0.941 0.000
F60.3 Emotionally unstable personality disorder
0.059 0.941 0.000
T36.9 Systemic antibiotic, unspecified
0.058 0.941 0.000
T36.8 Other systemic antibiotics
0.058 0.941 0.000
T36.7 Antifungal antibiotics, systemically used
0.058 0.941 0.000
T36.6 Rifamycins
0.058 0.941 0.000
T36.5 Aminoglycosides
0.058 0.941 0.000
T36.4 Tetracyclines
0.058 0.941 0.000
T36.3 Macrolides
0.058 0.941 0.000
T36.2 Chloramphenicol group
0.058 0.941 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.058 0.941 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.058 0.942 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.058 0.942 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.058 0.942 0.000
T46.7 Peripheral vasodilators
0.058 0.942 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.058 0.942 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.058 0.942 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.058 0.942 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.058 0.942 0.000
T45.0 Antiallergic and antiemetic drugs
0.057 0.942 0.000
F52.2 Failure of genital response
0.057 0.943 0.000
F40.2 Specific (isolated) phobias
0.056 0.944 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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