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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2106067
log Bayes Factor = 71.4793
Chromosome 6   position 31,048,263  (GRCh37) Explore rs2106067 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
R31 Unspecified haematuria
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.002 0.998
E10.9 Without complications
0.000 0.004 0.996
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.004 0.996
E16.2 Hypoglycaemia, unspecified
0.000 0.004 0.996
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.005 0.995
E16 Other disorders of pancreatic internal secretion
0.000 0.005 0.995
E10.3 With ophthalmic complications
0.000 0.007 0.993
L40 Psoriasis
0.000 0.007 0.993
L40.5 Arthropathic psoriasis
0.000 0.016 0.984
D86.9 Sarcoidosis, unspecified
0.000 0.018 0.982
D86 Sarcoidosis
0.000 0.019 0.981
E00-E07 Disorders of thyroid gland
0.107 0.035 0.859
D80-D89 Certain disorders involving the immune mechanism
0.000 0.036 0.964
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.044 0.956
L40.0 Psoriasis vulgaris
0.000 0.050 0.950
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.052 0.948
D70 Agranulocytosis
0.000 0.056 0.944
D50-D53 Nutritional anaemias
0.000 0.082 0.918
E10.2 With renal complications
0.000 0.083 0.917
E11 Non-insulin-dependent diabetes mellitus
0.000 0.093 0.907
D86.1 Sarcoidosis of lymph nodes
0.000 0.099 0.901
D51 Vitamin B12 deficiency anaemia
0.000 0.102 0.898
E10.8 With unspecified complications
0.000 0.121 0.879
E05 Thyrotoxicosis [hyperthyroidism]
0.018 0.125 0.857
E10.4 With neurological complications
0.000 0.132 0.868
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.135 0.865
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.138 0.862
D86.0 Sarcoidosis of lung
0.000 0.147 0.853
E11.5 With peripheral circulatory complications
0.000 0.148 0.852
E10.5 With peripheral circulatory complications
0.000 0.149 0.851
D72 Other disorders of white blood cells
0.000 0.170 0.830
D55-D59 Haemolytic anaemias
0.000 0.174 0.825
E10.6 With other specified complications
0.000 0.190 0.810
E11.3 With ophthalmic complications
0.000 0.202 0.798
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.205 0.795
D59 Acquired haemolytic anaemia
0.000 0.211 0.789
D53 Other nutritional anaemias
0.000 0.218 0.781
E11.4 With neurological complications
0.000 0.219 0.781
E50-E64 Other nutritional deficiencies
0.000 0.221 0.779
E03 Other hypothyroidism
0.474 0.224 0.302
D86.8 Sarcoidosis of other and combined sites
0.000 0.226 0.774
L40.4 Guttate psoriasis
0.000 0.235 0.765
L40.1 Generalised pustular psoriasis
0.000 0.235 0.765
E10.0 With coma
0.000 0.241 0.759
D83 Common variable immunodeficiency
0.000 0.241 0.759
D80 Immunodeficiency with predominantly antibody defects
0.000 0.244 0.756
D86.3 Sarcoidosis of skin
0.000 0.244 0.756
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.251 0.749
D72.8 Other specified disorders of white blood cells
0.000 0.253 0.747
D75 Other diseases of blood and blood-forming organs
0.000 0.260 0.740
E11.8 With unspecified complications
0.000 0.264 0.736
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.275 0.725
E55 Vitamin D deficiency
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.286 0.713
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.286 0.713
E16.4 Abnormal secretion of gastrin
0.000 0.286 0.713
E16.3 Increased secretion of glucagon
0.000 0.286 0.713
L40.3 Pustulosis palmaris et plantaris
0.000 0.288 0.712
L40.2 Acrodermatitis continua
0.000 0.288 0.712
E13 Other specified diabetes mellitus
0.000 0.293 0.707
E11.1 With ketoacidosis
0.000 0.294 0.706
D59.1 Other autoimmune haemolytic anaemias
0.000 0.305 0.695
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.077 0.308 0.616
E00 Congenital iodine-deficiency syndrome
0.077 0.308 0.616
D81 Combined immunodeficiencies
0.000 0.309 0.691
E40-E46 Malnutrition
0.000 0.309 0.691
E14 Unspecified diabetes mellitus
0.000 0.311 0.689
D53.9 Nutritional anaemia, unspecified
0.000 0.316 0.684
D74 Methaemoglobinaemia
0.000 0.320 0.680
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.320 0.680
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.320 0.680
E16.1 Other hypoglycaemia
0.000 0.325 0.675
E55.9 Vitamin D deficiency, unspecified
0.000 0.325 0.675
E02 Subclinical iodine-deficiency hypothyroidism
0.075 0.334 0.592
D82 Immunodeficiency associated with other major defects
0.000 0.340 0.660
E83.1 Disorders of iron metabolism
0.000 0.340 0.660
E11.6 With other specified complications
0.000 0.340 0.660
E11.7 With multiple complications
0.000 0.350 0.650
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.354 0.646
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.356 0.644
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.356 0.644
D51.2 Transcobalamin II deficiency
0.000 0.356 0.644
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.356 0.644
E06 Thyroiditis
0.057 0.365 0.578
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.371 0.629
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.371 0.629
E05.5 Thyroid crisis or storm
0.013 0.372 0.615
E05.4 Thyrotoxicosis factitia
0.013 0.372 0.615
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.013 0.372 0.615
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.013 0.372 0.615
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.375 0.625
E70-E90 Metabolic disorders
0.000 0.378 0.622
E83 Disorders of mineral metabolism
0.000 0.385 0.615
D83.9 Common variable immunodeficiency, unspecified
0.000 0.388 0.612
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.397 0.603
E20-E35 Disorders of other endocrine glands
0.000 0.398 0.602
D72.9 Disorder of white blood cells, unspecified
0.000 0.405 0.595
D72.0 Genetic anomalies of leukocytes
0.000 0.405 0.595
E27.1 Primary adrenocortical insufficiency
0.000 0.407 0.593
D55 Anaemia due to enzyme disorders
0.000 0.408 0.592
E27 Other disorders of adrenal gland
0.000 0.409 0.591
D72.1 Eosinophilia
0.000 0.412 0.587
E05.8 Other thyrotoxicosis
0.013 0.413 0.574
E51 Thiamine deficiency
0.000 0.415 0.585
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.416 0.584
D84 Other immunodeficiencies
0.000 0.419 0.580
D75.0 Familial erythrocytosis
0.000 0.421 0.579
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.430 0.570
E14.3 With ophthalmic complications
0.000 0.432 0.568
E88 Other metabolic disorders
0.000 0.434 0.566
D59.8 Other acquired haemolytic anaemias
0.000 0.435 0.565
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.435 0.565
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.435 0.565
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.435 0.565
D59.3 Haemolytic-uraemic syndrome
0.000 0.435 0.565
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.435 0.565
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.435 0.565
D57 Sickle-cell disorders
0.000 0.437 0.563
E14.8 With unspecified complications
0.000 0.439 0.561
D53.8 Other specified nutritional anaemias
0.000 0.440 0.560
D53.2 Scorbutic anaemia
0.000 0.440 0.560
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.440 0.560
D53.0 Protein deficiency anaemia
0.000 0.440 0.560
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.441 0.559
E63 Other nutritional deficiencies
0.000 0.441 0.559
E50 Vitamin A deficiency
0.000 0.441 0.559
E60 Dietary zinc deficiency
0.000 0.441 0.559
E59 Dietary selenium deficiency
0.000 0.441 0.559
E52 Niacin deficiency [pellagra]
0.000 0.441 0.559
E03.5 Myxoedema coma
0.340 0.444 0.216
E03.4 Atrophy of thyroid (acquired)
0.340 0.444 0.216
E03.3 Postinfectious hypothyroidism
0.340 0.444 0.216
E07 Other disorders of thyroid
0.125 0.447 0.427
E53 Deficiency of other B group vitamins
0.000 0.448 0.552
D50 Iron deficiency anaemia
0.000 0.448 0.552
E03.0 Congenital hypothyroidism with diffuse goitre
0.338 0.452 0.210
D83.8 Other common variable immunodeficiencies
0.000 0.456 0.544
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.456 0.544
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.456 0.544
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.456 0.544
E85 Amyloidosis
0.000 0.457 0.543
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.458 0.542
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.458 0.542
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.458 0.542
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.458 0.542
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.458 0.542
D58 Other hereditary haemolytic anaemias
0.000 0.459 0.541
E54 Ascorbic acid deficiency
0.000 0.464 0.536
E65-E68 Obesity and other hyperalimentation
0.000 0.465 0.535
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.355 0.465 0.180
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.466 0.534
E13.9 Without complications
0.000 0.467 0.533
E03.1 Congenital hypothyroidism without goitre
0.301 0.468 0.231
E14.1 With ketoacidosis
0.000 0.469 0.531
D75.2 Essential thrombocytosis
0.000 0.474 0.526
E14.6 With other specified complications
0.000 0.476 0.524
L40.8 Other psoriasis
0.000 0.479 0.521
E34 Other endocrine disorders
0.000 0.482 0.518
E06.9 Thyroiditis, unspecified
0.024 0.483 0.492
E55.0 Rickets, active
0.000 0.485 0.515
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.513
E12.8 With unspecified complications
0.000 0.486 0.513
E12.7 With multiple complications
0.000 0.486 0.513
E12.6 With other specified complications
0.000 0.486 0.513
E12.5 With peripheral circulatory complications
0.000 0.486 0.513
E12.4 With neurological complications
0.000 0.486 0.513
E12.3 With ophthalmic complications
0.000 0.486 0.513
E12.2 With renal complications
0.000 0.486 0.513
E12.1 With ketoacidosis
0.000 0.486 0.513
E12.0 With coma
0.000 0.486 0.513
E58 Dietary calcium deficiency
0.000 0.487 0.513
E56 Other vitamin deficiencies
0.000 0.492 0.508
E13.8 With unspecified complications
0.000 0.493 0.507
E13.7 With multiple complications
0.000 0.493 0.507
E13.6 With other specified complications
0.000 0.493 0.507
E13.5 With peripheral circulatory complications
0.000 0.493 0.507
E13.4 With neurological complications
0.000 0.493 0.507
E13.2 With renal complications
0.000 0.493 0.507
E13.1 With ketoacidosis
0.000 0.493 0.507
E13.0 With coma
0.000 0.493 0.507
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.495 0.504
E03.8 Other specified hypothyroidism
0.309 0.503 0.188
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.055 0.504 0.441
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.055 0.504 0.441
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.055 0.504 0.441
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.055 0.504 0.441
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.055 0.504 0.441
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.055 0.504 0.441
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.055 0.504 0.441
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.055 0.504 0.441
D81.9 Combined immunodeficiency, unspecified
0.000 0.504 0.495
D81.8 Other combined immunodeficiencies
0.000 0.504 0.495
D81.7 Major histocompatibility complex class II deficiency
0.000 0.504 0.495
D81.6 Major histocompatibility complex class I deficiency
0.000 0.504 0.495
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.504 0.495
D81.4 Nezelof's syndrome
0.000 0.504 0.495
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.504 0.495
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.504 0.495
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.504 0.495
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.504 0.495
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.505 0.495
E45 Retarded development following protein-energy malnutrition
0.000 0.505 0.495
E43 Unspecified severe protein-energy malnutrition
0.000 0.505 0.495
E42 Marasmic kwashiorkor
0.000 0.505 0.495
E41 Nutritional marasmus
0.000 0.505 0.495
E40 Kwashiorkor
0.000 0.505 0.495
E14.7 With multiple complications
0.000 0.506 0.494
E14.2 Withrenal complications
0.000 0.506 0.494
E14.0 With coma
0.000 0.506 0.494
D74.9 Methaemoglobinaemia, unspecified
0.000 0.512 0.488
D74.8 Other methaemoglobinaemias
0.000 0.512 0.488
D74.0 Congenital methaemoglobinaemia
0.000 0.512 0.488
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.013 0.513 0.474
D66 Hereditary factor VIII deficiency
0.000 0.514 0.486
E85.4 Organ-limited amyloidosis
0.000 0.516 0.484
E20 Hypoparathyroidism
0.000 0.519 0.481
E11.2 With renal complications
0.000 0.521 0.479
D75.1 Secondary polycythaemia
0.000 0.525 0.475
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.526 0.473
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.526 0.473
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.526 0.473
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.526 0.473
D82.2 Immunodeficiency with short-limbed stature
0.000 0.526 0.473
D82.0 Wiskott-Aldrich syndrome
0.000 0.526 0.473
E46 Unspecified protein-energy malnutrition
0.000 0.528 0.472
E79 Disorders of purine and pyrimidine metabolism
0.000 0.532 0.468
E13.3 With ophthalmic complications
0.000 0.534 0.466
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.535 0.465
E34.9 Endocrine disorder, unspecified
0.000 0.536 0.464
E70 Disorders of aromatic amino-acid metabolism
0.000 0.538 0.462
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.542 0.458
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.542 0.458
D52 Folate deficiency anaemia
0.000 0.543 0.456
E06.4 Drug-induced thyroiditis
0.041 0.545 0.414
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.041 0.545 0.414
E06.0 Acute thyroiditis
0.041 0.545 0.414
E14.5 With peripheral circulatory complications
0.000 0.545 0.454
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.546 0.454
D84.1 Defects in the complement system
0.000 0.547 0.453
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.548 0.452
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.549 0.451
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.549 0.451
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.549 0.451
E77 Disorders of glycoprotein metabolism
0.000 0.554 0.446
E76 Disorders of glycosaminoglycan metabolism
0.000 0.554 0.446
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.554 0.446
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.554 0.446
E51.2 Wernicke's encephalopathy
0.000 0.554 0.446
E25 Adrenogenital disorders
0.000 0.555 0.445
D82.1 Di George's syndrome
0.000 0.557 0.442
E88.9 Metabolic disorder, unspecified
0.000 0.558 0.442
E83.8 Other disorders of mineral metabolism
0.000 0.559 0.441
E83.2 Disorders of zinc metabolism
0.000 0.559 0.441
E83.0 Disorders of copper metabolism
0.000 0.559 0.441
D67 Hereditary factor IX deficiency
0.000 0.560 0.440
K90 Intestinal malabsorption
0.000 0.561 0.439
E14.4 With neurological complications
0.000 0.562 0.438
D50.9 Iron deficiency anaemia, unspecified
0.000 0.566 0.434
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.568 0.432
E32 Diseases of thymus
0.000 0.568 0.432
E31 Polyglandular dysfunction
0.000 0.568 0.432
E30 Disorders of puberty, not elsewhere classified
0.000 0.568 0.432
E04 Other non-toxic goitre
0.008 0.570 0.422
E05.9 Thyrotoxicosis, unspecified
0.001 0.571 0.428
D50.8 Other iron deficiency anaemias
0.000 0.574 0.426
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.575 0.424
D55.8 Other anaemias due to enzyme disorders
0.000 0.575 0.424
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.575 0.424
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.575 0.424
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.575 0.424
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.575 0.424
E34.0 Carcinoid syndrome
0.000 0.576 0.424
E27.5 Adrenomedullary hyperfunction
0.000 0.576 0.424
E27.0 Other adrenocortical overactivity
0.000 0.576 0.424
E53.9 Vitamin B deficiency, unspecified
0.000 0.577 0.422
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.578 0.422
D69 Purpura and other haemorrhagic conditions
0.000 0.580 0.420
E51.9 Thiamine deficiency, unspecified
0.000 0.580 0.419
E51.8 Other manifestations of thiamine deficiency
0.000 0.580 0.419
E51.1 Beriberi
0.000 0.580 0.419
E88.3 Tumour lysis syndrome
0.000 0.582 0.418
E84 Cystic fibrosis
0.000 0.583 0.417
D84.8 Other specified immunodeficiencies
0.000 0.583 0.416
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.583 0.416
E27.2 Addisonian crisis
0.000 0.584 0.416
E85.3 Secondary systemic amyloidosis
0.000 0.590 0.410
E72 Other disorders of amino-acid metabolism
0.000 0.591 0.409
E06.3 Autoimmune thyroiditis
0.022 0.591 0.387
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.595 0.405
D57.8 Other sickle-cell disorders
0.000 0.596 0.404
D57.3 Sickle-cell trait
0.000 0.596 0.404
D57.2 Double heterozygous sickling disorders
0.000 0.596 0.404
D57.0 Sickle-cell anaemia with crisis
0.000 0.596 0.404
E61 Deficiency of other nutrient elements
0.000 0.597 0.403
E50.9 Vitamin A deficiency, unspecified
0.000 0.599 0.401
E50.8 Other manifestations of vitamin A deficiency
0.000 0.599 0.401
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.599 0.401
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.599 0.401
E50.5 Vitamin A deficiency with night blindness
0.000 0.599 0.401
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.599 0.401
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.599 0.401
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.599 0.401
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.599 0.401
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.599 0.401
E63.9 Nutritional deficiency, unspecified
0.000 0.599 0.401
E63.8 Other specified nutritional deficiencies
0.000 0.599 0.401
E63.1 Imbalance of constituents of food intake
0.000 0.599 0.401
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.599 0.401
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.599 0.401
E64.8 Sequelae of other nutritional deficiencies
0.000 0.599 0.401
E64.3 Sequelae of rickets
0.000 0.599 0.401
E64.2 Sequelae of vitamin C deficiency
0.000 0.599 0.401
E64.1 Sequelae of vitamin A deficiency
0.000 0.599 0.401
E64.0 Sequelae of protein-energy malnutrition
0.000 0.599 0.401
E06.1 Subacute thyroiditis
0.045 0.599 0.356
E07.8 Other specified disorders of thyroid
0.066 0.599 0.335
D58.2 Other haemoglobinopathies
0.000 0.600 0.400
D76.3 Other histiocytosis syndromes
0.000 0.600 0.399
E11.0 With coma
0.000 0.601 0.398
E27.8 Other specified disorders of adrenal gland
0.000 0.601 0.399
E22 Hyperfunction of pituitary gland
0.000 0.602 0.398
D56 Thalassaemia
0.001 0.603 0.396
E07.1 Dyshormogenetic goitre
0.090 0.604 0.307
E07.0 Hypersecretion of calcitonin
0.090 0.604 0.307
E53.1 Pyridoxine deficiency
0.000 0.604 0.396
E53.0 Riboflavin deficiency
0.000 0.604 0.396
D50.1 Sideropenic dysphagia
0.000 0.604 0.396
E20.9 Hypoparathyroidism, unspecified
0.000 0.605 0.395
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.605 0.395
E85.8 Other amyloidosis
0.000 0.611 0.389
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.611 0.389
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.611 0.389
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.611 0.389
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.612 0.388
D58.1 Hereditary elliptocytosis
0.000 0.612 0.388
E67 Other hyperalimentation
0.000 0.616 0.384
E68 Sequelae of hyperalimentation
0.000 0.616 0.384
D89.3 Immune reconstitution syndrome
0.000 0.617 0.383
E06.5 Other chronic thyroiditis
0.046 0.617 0.337
E88.8 Other specified metabolic disorders
0.000 0.617 0.383
E74 Other disorders of carbohydrate metabolism
0.000 0.622 0.378
D57.1 Sickle-cell anaemia without crisis
0.000 0.625 0.375
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.627 0.373
E34.5 Androgen resistance syndrome
0.000 0.628 0.372
E34.4 Constitutional tall stature
0.000 0.628 0.372
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.628 0.372
E34.1 Other hypersecretion of intestinal hormones
0.000 0.628 0.372
E85.9 Amyloidosis, unspecified
0.000 0.629 0.371
D89.1 Cryoglobulinaemia
0.000 0.633 0.367
E56.9 Vitamin deficiency, unspecified
0.000 0.636 0.364
E56.8 Deficiency of other vitamins
0.000 0.636 0.364
E56.0 Deficiency of vitamin E
0.000 0.636 0.364
E73 Lactose intolerance
0.000 0.636 0.363
E29 Testicular dysfunction
0.000 0.642 0.358
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.642 0.357
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.643 0.357
E53.8 Deficiency of other specified B group vitamins
0.000 0.643 0.357
E34.3 Short stature, not elsewhere classified
0.000 0.644 0.356
E44.1 Mild protein-energy malnutrition
0.000 0.645 0.355
E44.0 Moderate protein-energy malnutrition
0.000 0.645 0.355
E24 Cushing's syndrome
0.000 0.647 0.353
E04.0 Non-toxic diffuse goitre
0.004 0.647 0.349
K90.9 Intestinal malabsorption, unspecified
0.000 0.648 0.352
D69.2 Other nonthrombocytopenic purpura
0.000 0.651 0.349
E70.3 Albinism
0.000 0.652 0.348
E20.8 Other hypoparathyroidism
0.000 0.655 0.345
E20.1 Pseudohypoparathyroidism
0.000 0.655 0.345
E20.0 Idiopathic hypoparathyroidism
0.000 0.655 0.345
E88.2 Lipomatosis, not elsewhere classified
0.000 0.657 0.343
D69.5 Secondary thrombocytopenia
0.000 0.658 0.342
D58.0 Hereditary spherocytosis
0.000 0.660 0.339
D69.6 Thrombocytopenia, unspecified
0.000 0.663 0.337
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.664 0.336
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.664 0.335
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.664 0.335
E79.1 Lesch-Nyhan syndrome
0.000 0.664 0.335
E04.9 Non-toxic goitre, unspecified
0.001 0.665 0.334
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.667 0.332
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.668 0.332
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.668 0.332
E70.2 Disorders of tyrosine metabolism
0.000 0.668 0.332
E70.1 Other hyperphenylalaninaemias
0.000 0.668 0.332
E70.0 Classical phenylketonuria
0.000 0.668 0.332
D52.8 Other folate deficiency anaemias
0.000 0.672 0.327
D52.1 Drug-induced folate deficiency anaemia
0.000 0.672 0.327
D52.0 Dietary folate deficiency anaemia
0.000 0.672 0.327
E66 Obesity
0.000 0.680 0.320
E71.3 Disorders of fatty-acid metabolism
0.000 0.680 0.320
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.680 0.320
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.680 0.320
E71.0 Maple-syrup-urine disease
0.000 0.680 0.320
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.680 0.320
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.680 0.320
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.680 0.320
E76.2 Other mucopolysaccharidoses
0.000 0.680 0.320
E76.1 Mucopolysaccharidosis, type II
0.000 0.680 0.320
E76.0 Mucopolysaccharidosis, type I
0.000 0.680 0.320
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.680 0.320
E77.8 Other disorders of glycoprotein metabolism
0.000 0.680 0.320
E77.1 Defects in glycoprotein degradation
0.000 0.680 0.320
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.680 0.320
E22.1 Hyperprolactinaemia
0.000 0.680 0.320
E25.9 Adrenogenital disorder, unspecified
0.000 0.681 0.319
E25.8 Other adrenogenital disorders
0.000 0.681 0.319
E86 Volume depletion
0.000 0.682 0.318
K90.3 Pancreatic steatorrhoea
0.000 0.685 0.315
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.685 0.315
K90.1 Tropical sprue
0.000 0.685 0.315
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.686 0.313
E56.1 Deficiency of vitamin K
0.000 0.687 0.313
E26 Hyperaldosteronism
0.000 0.690 0.310
E30.9 Disorder of puberty, unspecified
0.000 0.690 0.309
E30.8 Other disorders of puberty
0.000 0.690 0.309
E30.1 Precocious puberty
0.000 0.690 0.309
E30.0 Delayed puberty
0.000 0.690 0.309
E31.9 Polyglandular dysfunction, unspecified
0.000 0.690 0.309
E31.8 Other polyglandular dysfunction
0.000 0.690 0.309
E31.1 Polyglandular hyperfunction
0.000 0.690 0.309
E31.0 Autoimmune polyglandular failure
0.000 0.690 0.309
E32.9 Disease of thymus, unspecified
0.000 0.690 0.309
E32.8 Other diseases of thymus
0.000 0.690 0.309
E32.1 Abscess of thymus
0.000 0.690 0.309
E32.0 Persistent hyperplasia of thymus
0.000 0.690 0.309
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.690 0.309
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.690 0.309
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.690 0.309
E04.8 Other specified non-toxic goitre
0.006 0.691 0.303
D69.9 Haemorrhagic condition, unspecified
0.000 0.693 0.307
E65 Localised adiposity
0.000 0.697 0.303
K90.8 Other intestinal malabsorption
0.000 0.698 0.301
D69.8 Other specified haemorrhagic conditions
0.000 0.699 0.301
E84.8 Cystic fibrosis with other manifestations
0.000 0.701 0.299
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.701 0.299
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.701 0.299
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.706 0.293
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.706 0.293
E72.5 Disorders of glycine metabolism
0.000 0.706 0.293
E72.4 Disorders of ornithine metabolism
0.000 0.706 0.293
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.706 0.293
E72.2 Disorders of urea cycle metabolism
0.000 0.706 0.293
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.706 0.293
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.709 0.291
E34.8 Other specified endocrine disorders
0.000 0.710 0.289
E61.9 Deficiency of nutrient element, unspecified
0.000 0.711 0.289
E61.8 Deficiency of other specified nutrient elements
0.000 0.711 0.289
E61.7 Deficiency of multiple nutrient elements
0.000 0.711 0.289
E61.6 Vanadium deficiency
0.000 0.711 0.289
E61.5 Molybdenum deficiency
0.000 0.711 0.289
E61.4 Chromium deficiency
0.000 0.711 0.289
E61.3 Manganese deficiency
0.000 0.711 0.289
E61.0 Copper deficiency
0.000 0.711 0.289
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.714 0.286
E22.8 Other hyperfunction of pituitary gland
0.000 0.714 0.286
D56.9 Thalassaemia, unspecified
0.001 0.715 0.284
D56.8 Other thalassaemias
0.001 0.715 0.284
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.001 0.715 0.284
D56.2 Delta-beta thalassaemia
0.001 0.715 0.284
D56.0 Alpha thalassaemia
0.001 0.715 0.284
D69.1 Qualitative platelet defects
0.000 0.716 0.284
E22.0 Acromegaly and pituitary gigantism
0.000 0.716 0.284
E27.9 Disorder of adrenal gland, unspecified
0.000 0.716 0.283
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.721 0.279
E67.8 Other specified hyperalimentation
0.000 0.724 0.275
E67.3 Hypervitaminosis D
0.000 0.724 0.275
E67.2 Megavitamin-B6 syndrome
0.000 0.724 0.275
E67.1 Hypercarotenaemia
0.000 0.724 0.275
E67.0 Hypervitaminosis A
0.000 0.724 0.275
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.726 0.274
E24.0 Pituitary-dependent Cushing's disease
0.000 0.726 0.273
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.728 0.272
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.728 0.272
E66.0 Obesity due to excess calories
0.000 0.728 0.272
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.729 0.271
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.729 0.271
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.729 0.271
E74.2 Disorders of galactose metabolism
0.000 0.729 0.271
E74.1 Disorders of fructose metabolism
0.000 0.729 0.271
E74.0 Glycogen storage disease
0.000 0.729 0.271
E84.9 Cystic fibrosis, unspecified
0.000 0.730 0.270
D69.4 Other primary thrombocytopenia
0.000 0.737 0.263
E73.8 Other lactose intolerance
0.000 0.739 0.261
E73.1 Secondary lactase deficiency
0.000 0.739 0.261
E73.0 Congenital lactase deficiency
0.000 0.739 0.261
D73 Diseases of spleen
0.000 0.741 0.259
E29.9 Testicular dysfunction, unspecified
0.000 0.743 0.257
E29.8 Other testicular dysfunction
0.000 0.743 0.257
E29.0 Testicular hyperfunction
0.000 0.743 0.257
E75.6 Lipid storage disorder, unspecified
0.000 0.743 0.256
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.743 0.256
E75.3 Sphingolipidosis, unspecified
0.000 0.743 0.256

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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