TreeWAS – Variant ID: rs2149085

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.002	0.998
E05.9 Thyrotoxicosis, unspecified	0.000	0.003	0.997
E03.8 Other specified hypothyroidism	0.000	0.062	0.938
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.092	0.908
E07 Other disorders of thyroid	0.000	0.139	0.861
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.160	0.840
E03.1 Congenital hypothyroidism without goitre	0.000	0.211	0.789
E07.9 Disorder of thyroid, unspecified	0.000	0.220	0.780
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.304	0.696
C44.3 Skin of other and unspecified parts of face	0.645	0.355	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.376	0.624
E07.1 Dyshormogenetic goitre	0.000	0.383	0.617
E07.0 Hypersecretion of calcitonin	0.000	0.383	0.617
E05.8 Other thyrotoxicosis	0.000	0.397	0.602
E07.8 Other specified disorders of thyroid	0.000	0.436	0.563
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E06 Thyroiditis	0.000	0.490	0.509
E06.5 Other chronic thyroiditis	0.000	0.596	0.404
E06.4 Drug-induced thyroiditis	0.000	0.635	0.365
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.635	0.365
E06.0 Acute thyroiditis	0.000	0.635	0.365
E06.1 Subacute thyroiditis	0.000	0.649	0.351
C44 Other malignant neoplasms of skin	0.338	0.662	0.000
C44.5 Skin of trunk	0.334	0.666	0.000
C44.6 Skin of upper limb, including shoulder	0.317	0.683	0.000
E06.3 Autoimmune thyroiditis	0.000	0.700	0.300
C44.2 Skin of ear and external auricular canal	0.246	0.754	0.000
C44.8 Overlapping lesion of skin	0.242	0.758	0.000
E04 Other non-toxic goitre	0.000	0.769	0.231
E06.9 Thyroiditis, unspecified	0.001	0.789	0.210
C43-C44 Melanoma and other malignant neoplasms of skin	0.208	0.792	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.207	0.793	0.000
C43 Malignant melanoma of skin	0.182	0.818	0.000
C43.5 Malignant melanoma of trunk	0.182	0.818	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.821	0.179
E04.8 Other specified non-toxic goitre	0.000	0.834	0.166
C43.4 Malignant melanoma of scalp and neck	0.155	0.845	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.149	0.851	0.000
C43.9 Malignant melanoma of skin, unspecified	0.135	0.865	0.000
K50.9 Crohn's disease, unspecified	0.000	0.868	0.132
C43.8 Overlapping malignant melanoma of skin	0.131	0.869	0.000
C43.0 Malignant melanoma of lip	0.131	0.869	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.870	0.130
C43.1 Malignant melanoma of eyelid, including canthus	0.127	0.873	0.000
K50.0 Crohn's disease of small intestine	0.000	0.874	0.126
K50.1 Crohn's disease of large intestine	0.000	0.886	0.114
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.893	0.107
K50.8 Other Crohn's disease	0.000	0.896	0.104
E04.9 Non-toxic goitre, unspecified	0.000	0.896	0.104
E50-E64 Other nutritional deficiencies	0.000	0.905	0.095
E53 Deficiency of other B group vitamins	0.000	0.909	0.091
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.910	0.090
E53.8 Deficiency of other specified B group vitamins	0.000	0.910	0.090
C43.2 Malignant melanoma of ear and external auricular canal	0.084	0.915	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.916	0.084
L43.9 Lichen planus, unspecified	0.000	0.921	0.079
E58 Dietary calcium deficiency	0.000	0.921	0.079
E16 Other disorders of pancreatic internal secretion	0.000	0.922	0.078
E04.2 Non-toxic multinodular goitre	0.000	0.924	0.075
E16.2 Hypoglycaemia, unspecified	0.000	0.927	0.073
K50-K52 Noninfective enteritis and colitis	0.000	0.929	0.071
C44.0 Skin of lip	0.071	0.929	0.000
E51 Thiamine deficiency	0.000	0.929	0.071
E10-E14 Diabetes mellitus	0.000	0.929	0.071
E14 Unspecified diabetes mellitus	0.000	0.931	0.069
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.932	0.068
E63 Other nutritional deficiencies	0.000	0.932	0.068
E50 Vitamin A deficiency	0.000	0.932	0.068
E60 Dietary zinc deficiency	0.000	0.932	0.068
E59 Dietary selenium deficiency	0.000	0.932	0.068
E52 Niacin deficiency [pellagra]	0.000	0.932	0.068
K51 Ulcerative colitis	0.000	0.932	0.068
E40-E46 Malnutrition	0.000	0.933	0.067
E54 Ascorbic acid deficiency	0.000	0.934	0.065
E53.1 Pyridoxine deficiency	0.000	0.935	0.065
E53.0 Riboflavin deficiency	0.000	0.935	0.065
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.935	0.065
E15 Nondiabetic hypoglycaemic coma	0.000	0.935	0.065
K51.5 Mucosal proctocolitis	0.000	0.937	0.063
E14.9 Without complications	0.000	0.937	0.063
E56 Other vitamin deficiencies	0.000	0.940	0.060
E53.9 Vitamin B deficiency, unspecified	0.000	0.940	0.060
E61 Deficiency of other nutrient elements	0.000	0.942	0.058
E14.4 With neurological complications	0.000	0.943	0.057
K51.8 Other ulcerative colitis	0.000	0.943	0.057
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.944	0.056
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.944	0.056
E16.4 Abnormal secretion of gastrin	0.000	0.944	0.056
E16.3 Increased secretion of glucagon	0.000	0.944	0.056
E14.3 With ophthalmic complications	0.000	0.945	0.055
E51.2 Wernicke's encephalopathy	0.000	0.946	0.054
E14.1 With ketoacidosis	0.000	0.947	0.053
E14.5 With peripheral circulatory complications	0.000	0.948	0.052
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.948	0.051
E13 Other specified diabetes mellitus	0.000	0.949	0.051
E51.9 Thiamine deficiency, unspecified	0.000	0.949	0.051
E51.8 Other manifestations of thiamine deficiency	0.000	0.949	0.051
E51.1 Beriberi	0.000	0.949	0.051
E12 Malnutrition-related diabetes mellitus	0.000	0.949	0.051
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.949	0.051
E14.2 Withrenal complications	0.000	0.950	0.050
E14.7 With multiple complications	0.000	0.950	0.049
E14.0 With coma	0.000	0.950	0.049
E50.9 Vitamin A deficiency, unspecified	0.000	0.951	0.049
E50.8 Other manifestations of vitamin A deficiency	0.000	0.951	0.049
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.951	0.049
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.951	0.049
E50.5 Vitamin A deficiency with night blindness	0.000	0.951	0.049
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.951	0.049
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.951	0.049
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.951	0.049
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.951	0.049
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.951	0.049
E63.9 Nutritional deficiency, unspecified	0.000	0.951	0.049
E63.8 Other specified nutritional deficiencies	0.000	0.951	0.049
E63.1 Imbalance of constituents of food intake	0.000	0.951	0.049
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.951	0.049
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.951	0.049
E64.8 Sequelae of other nutritional deficiencies	0.000	0.951	0.049
E64.3 Sequelae of rickets	0.000	0.951	0.049
E64.2 Sequelae of vitamin C deficiency	0.000	0.951	0.049
E64.1 Sequelae of vitamin A deficiency	0.000	0.951	0.049
E64.0 Sequelae of protein-energy malnutrition	0.000	0.951	0.049
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.951	0.048
E45 Retarded development following protein-energy malnutrition	0.000	0.951	0.048
E43 Unspecified severe protein-energy malnutrition	0.000	0.951	0.048
E42 Marasmic kwashiorkor	0.000	0.951	0.048
E41 Nutritional marasmus	0.000	0.951	0.048
E40 Kwashiorkor	0.000	0.951	0.048
E16.1 Other hypoglycaemia	0.000	0.952	0.048
E14.6 With other specified complications	0.000	0.952	0.048
E14.8 With unspecified complications	0.000	0.953	0.047
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.954	0.046
E56.9 Vitamin deficiency, unspecified	0.000	0.956	0.043
E56.8 Deficiency of other vitamins	0.000	0.956	0.043
E56.0 Deficiency of vitamin E	0.000	0.956	0.043
E55 Vitamin D deficiency	0.000	0.957	0.042
C43.6 Malignant melanoma of upper limb, including shoulder	0.042	0.958	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.958	0.041
E61.8 Deficiency of other specified nutrient elements	0.000	0.958	0.041
E61.7 Deficiency of multiple nutrient elements	0.000	0.958	0.041
E61.6 Vanadium deficiency	0.000	0.958	0.041
E61.5 Molybdenum deficiency	0.000	0.958	0.041
E61.4 Chromium deficiency	0.000	0.958	0.041
E61.3 Manganese deficiency	0.000	0.958	0.041
E61.0 Copper deficiency	0.000	0.958	0.041
E61.2 Magnesium deficiency	0.000	0.961	0.039
C44.7 Skin of lower limb, including hip	0.039	0.961	0.000
K51.4 Pseudopolyposis of colon	0.000	0.961	0.039
E46 Unspecified protein-energy malnutrition	0.000	0.961	0.039
E13.3 With ophthalmic complications	0.000	0.962	0.038
E20-E35 Disorders of other endocrine glands	0.000	0.962	0.038
E13.8 With unspecified complications	0.000	0.963	0.037
E13.7 With multiple complications	0.000	0.963	0.037
E13.6 With other specified complications	0.000	0.963	0.037
E13.5 With peripheral circulatory complications	0.000	0.963	0.037
E13.4 With neurological complications	0.000	0.963	0.037
E13.2 With renal complications	0.000	0.963	0.037
E13.1 With ketoacidosis	0.000	0.963	0.037
E13.0 With coma	0.000	0.963	0.037
E12.9 Without complications	0.000	0.963	0.037
E12.8 With unspecified complications	0.000	0.963	0.037
E12.7 With multiple complications	0.000	0.963	0.037
E12.6 With other specified complications	0.000	0.963	0.037
E12.5 With peripheral circulatory complications	0.000	0.963	0.037
E12.4 With neurological complications	0.000	0.963	0.037
E12.3 With ophthalmic complications	0.000	0.963	0.037
E12.2 With renal complications	0.000	0.963	0.037
E12.1 With ketoacidosis	0.000	0.963	0.037
E12.0 With coma	0.000	0.963	0.037
E13.9 Without complications	0.000	0.964	0.036
E23.0 Hypopituitarism	0.000	0.964	0.036
E65-E68 Obesity and other hyperalimentation	0.000	0.964	0.036
E56.1 Deficiency of vitamin K	0.000	0.964	0.035
E23 Hypofunction and other disorders of pituitary gland	0.000	0.964	0.036
E44.1 Mild protein-energy malnutrition	0.000	0.965	0.035
E44.0 Moderate protein-energy malnutrition	0.000	0.965	0.035
C44.4 Skin of scalp and neck	0.035	0.965	0.000
E61.1 Iron deficiency	0.000	0.966	0.034
L43 Lichen planus	0.000	0.967	0.033
E55.0 Rickets, active	0.000	0.969	0.030
E23.7 Disorder of pituitary gland, unspecified	0.000	0.972	0.028
E26 Hyperaldosteronism	0.000	0.972	0.028
E25 Adrenogenital disorders	0.000	0.972	0.028
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.973	0.027
E32 Diseases of thymus	0.000	0.973	0.027
E30 Disorders of puberty, not elsewhere classified	0.000	0.973	0.027
E31 Polyglandular dysfunction	0.000	0.973	0.027
E24 Cushing's syndrome	0.000	0.973	0.027
E67 Other hyperalimentation	0.000	0.974	0.026
E68 Sequelae of hyperalimentation	0.000	0.974	0.026
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.974	0.026
E23.1 Drug-induced hypopituitarism	0.000	0.974	0.026
K51.9 Ulcerative colitis, unspecified	0.000	0.974	0.026
K51.2 Ulcerative (chronic) proctitis	0.000	0.975	0.025
E28 Ovarian dysfunction	0.000	0.975	0.025
L43.8 Other lichen planus	0.000	0.975	0.024
E23.2 Diabetes insipidus	0.000	0.976	0.024
E22 Hyperfunction of pituitary gland	0.000	0.976	0.024
E10 Insulin-dependent diabetes mellitus	0.000	0.976	0.024
L43.3 Subacute (active) lichen planus	0.000	0.976	0.024
L43.2 Lichenoid drug reaction	0.000	0.976	0.024
L43.1 Bullous lichen planus	0.000	0.976	0.024
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.977	0.023
C44.1 Skin of eyelid, including canthus	0.023	0.977	0.000
E29 Testicular dysfunction	0.000	0.977	0.022
E26.9 Hyperaldosteronism, unspecified	0.000	0.978	0.022
E28.3 Primary ovarian failure	0.000	0.978	0.022
L43.0 Hypertrophic lichen planus	0.000	0.978	0.022
E70-E90 Metabolic disorders	0.000	0.978	0.022
E20 Hypoparathyroidism	0.000	0.978	0.021
E22.0 Acromegaly and pituitary gigantism	0.000	0.979	0.021
E24.9 Cushing's syndrome, unspecified	0.000	0.979	0.021
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.979	0.021
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.980	0.020
E26.8 Other hyperaldosteronism	0.000	0.980	0.020
E26.1 Secondary hyperaldosteronism	0.000	0.980	0.020
E25.9 Adrenogenital disorder, unspecified	0.000	0.980	0.020
E25.8 Other adrenogenital disorders	0.000	0.980	0.020
E30.9 Disorder of puberty, unspecified	0.000	0.980	0.020
E30.8 Other disorders of puberty	0.000	0.980	0.020
E30.1 Precocious puberty	0.000	0.980	0.020
E30.0 Delayed puberty	0.000	0.980	0.020
E32.9 Disease of thymus, unspecified	0.000	0.980	0.020
E32.8 Other diseases of thymus	0.000	0.980	0.020
E32.1 Abscess of thymus	0.000	0.980	0.020
E32.0 Persistent hyperplasia of thymus	0.000	0.980	0.020
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.980	0.020
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.980	0.020
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.980	0.020
E31.9 Polyglandular dysfunction, unspecified	0.000	0.980	0.020
E31.8 Other polyglandular dysfunction	0.000	0.980	0.020
E31.1 Polyglandular hyperfunction	0.000	0.980	0.020
E31.0 Autoimmune polyglandular failure	0.000	0.980	0.020
E83 Disorders of mineral metabolism	0.000	0.980	0.020
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.980	0.020
E24.3 Ectopic ACTH syndrome	0.000	0.980	0.020
E24.1 Nelson's syndrome	0.000	0.980	0.020
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.980	0.020
E24.0 Pituitary-dependent Cushing's disease	0.000	0.980	0.020
E89.2 Postprocedural hypoparathyroidism	0.000	0.981	0.019
E10.4 With neurological complications	0.000	0.981	0.019
E89.0 Postprocedural hypothyroidism	0.000	0.981	0.019
E24.8 Other Cushing's syndrome	0.000	0.981	0.019
E67.8 Other specified hyperalimentation	0.000	0.981	0.019
E67.3 Hypervitaminosis D	0.000	0.981	0.019
E67.2 Megavitamin-B6 syndrome	0.000	0.981	0.019
E67.1 Hypercarotenaemia	0.000	0.981	0.019
E67.0 Hypervitaminosis A	0.000	0.981	0.019
K52 Other non-infective gastro-enteritis and colitis	0.000	0.981	0.019
E24.2 Drug-induced Cushing's syndrome	0.000	0.981	0.019
E10.1 With ketoacidosis	0.000	0.981	0.019
E10.0 With coma	0.000	0.981	0.018
E28.9 Ovarian dysfunction, unspecified	0.000	0.982	0.018
E28.8 Other ovarian dysfunction	0.000	0.982	0.018
E28.1 Androgen excess	0.000	0.982	0.018
E28.0 Oestrogen excess	0.000	0.982	0.018
E21.2 Other hyperparathyroidism	0.000	0.982	0.018
E26.0 Primary hyperaldosteronism	0.000	0.982	0.018
E10.7 With multiple complications	0.000	0.982	0.018
E10.6 With other specified complications	0.000	0.982	0.018
E83.1 Disorders of iron metabolism	0.000	0.982	0.018
E83.3 Disorders of phosphorus metabolism	0.000	0.982	0.018
E23.6 Other disorders of pituitary gland	0.000	0.982	0.017
E27 Other disorders of adrenal gland	0.000	0.982	0.018
E10.9 Without complications	0.000	0.982	0.018
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.982	0.017
E22.8 Other hyperfunction of pituitary gland	0.000	0.982	0.017
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.983	0.017
K52.1 Toxic gastro-enteritis and colitis	0.000	0.983	0.017
E88 Other metabolic disorders	0.000	0.983	0.017
E79 Disorders of purine and pyrimidine metabolism	0.000	0.983	0.016
E72 Other disorders of amino-acid metabolism	0.000	0.983	0.016
E10.2 With renal complications	0.000	0.983	0.016
E29.9 Testicular dysfunction, unspecified	0.000	0.984	0.016
E29.8 Other testicular dysfunction	0.000	0.984	0.016
E29.0 Testicular hyperfunction	0.000	0.984	0.016
E74 Other disorders of carbohydrate metabolism	0.000	0.984	0.016
E77 Disorders of glycoprotein metabolism	0.000	0.984	0.016
E76 Disorders of glycosaminoglycan metabolism	0.000	0.984	0.016
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.984	0.016
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.984	0.016
E20.8 Other hypoparathyroidism	0.000	0.984	0.015
E20.1 Pseudohypoparathyroidism	0.000	0.984	0.015
E20.0 Idiopathic hypoparathyroidism	0.000	0.984	0.015
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.984	0.016
E21.4 Other specified disorders of parathyroid gland	0.000	0.984	0.016
E70 Disorders of aromatic amino-acid metabolism	0.000	0.984	0.015
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.985	0.015
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.985	0.015
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.985	0.015
E89.1 Postprocedural hypoinsulinaemia	0.000	0.985	0.015
E84 Cystic fibrosis	0.000	0.985	0.015
E21.3 Hyperparathyroidism, unspecified	0.000	0.985	0.015
E73 Lactose intolerance	0.000	0.985	0.015
E85 Amyloidosis	0.000	0.985	0.015
E89.5 Postprocedural testicular hypofunction	0.000	0.985	0.015
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.985	0.014
E83.8 Other disorders of mineral metabolism	0.000	0.986	0.014
E83.2 Disorders of zinc metabolism	0.000	0.986	0.014
E83.0 Disorders of copper metabolism	0.000	0.986	0.014
E83.4 Disorders of magnesium metabolism	0.000	0.986	0.014
E88.2 Lipomatosis, not elsewhere classified	0.000	0.986	0.014
E66 Obesity	0.000	0.987	0.013
E10.8 With unspecified complications	0.000	0.987	0.013
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.987	0.013
E65 Localised adiposity	0.000	0.987	0.013
E89.3 Postprocedural hypopituitarism	0.000	0.987	0.013
E22.1 Hyperprolactinaemia	0.000	0.987	0.013
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.987	0.013
E27.5 Adrenomedullary hyperfunction	0.000	0.987	0.013
E27.0 Other adrenocortical overactivity	0.000	0.987	0.013
E27.1 Primary adrenocortical insufficiency	0.000	0.987	0.013
E88.8 Other specified metabolic disorders	0.000	0.987	0.013
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.987	0.013
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.987	0.013
E72.0 Disorders of amino-acid transport	0.000	0.987	0.012
E88.9 Metabolic disorder, unspecified	0.000	0.987	0.012
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.988	0.012
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.988	0.012
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.988	0.012
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.988	0.012
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.988	0.012
E79.1 Lesch-Nyhan syndrome	0.000	0.988	0.012
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.988	0.012
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.988	0.012
E72.5 Disorders of glycine metabolism	0.000	0.988	0.012
E72.4 Disorders of ornithine metabolism	0.000	0.988	0.012
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.988	0.012
E72.2 Disorders of urea cycle metabolism	0.000	0.988	0.012
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.988	0.012
E89.4 Postprocedural ovarian failure	0.000	0.988	0.012
E34 Other endocrine disorders	0.001	0.988	0.011
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.988	0.012
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.988	0.012
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.988	0.012
E74.2 Disorders of galactose metabolism	0.000	0.988	0.012
E74.1 Disorders of fructose metabolism	0.000	0.988	0.012
E74.0 Glycogen storage disease	0.000	0.988	0.012
E88.3 Tumour lysis syndrome	0.000	0.988	0.012
E71.3 Disorders of fatty-acid metabolism	0.000	0.988	0.012
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.988	0.012
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.988	0.012
E71.0 Maple-syrup-urine disease	0.000	0.988	0.012
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.988	0.012
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.988	0.012
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.988	0.012
E76.2 Other mucopolysaccharidoses	0.000	0.988	0.012
E76.1 Mucopolysaccharidosis, type II	0.000	0.988	0.012
E76.0 Mucopolysaccharidosis, type I	0.000	0.988	0.012
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.988	0.012
E77.8 Other disorders of glycoprotein metabolism	0.000	0.988	0.012
E77.1 Defects in glycoprotein degradation	0.000	0.988	0.012
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.988	0.012
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.988	0.012
E29.1 Testicular hypofunction	0.000	0.988	0.011
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.989	0.011
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.989	0.011
E70.2 Disorders of tyrosine metabolism	0.000	0.989	0.011
E70.1 Other hyperphenylalaninaemias	0.000	0.989	0.011
E70.0 Classical phenylketonuria	0.000	0.989	0.011
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.989	0.011
E85.8 Other amyloidosis	0.000	0.989	0.011
E75.6 Lipid storage disorder, unspecified	0.000	0.989	0.011
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.989	0.011
E75.3 Sphingolipidosis, unspecified	0.000	0.989	0.011
E75.1 Other gangliosidosis	0.000	0.989	0.011
E75.0 GM2 gangliosidosis	0.000	0.989	0.011
E84.9 Cystic fibrosis, unspecified	0.000	0.989	0.011
E85.4 Organ-limited amyloidosis	0.000	0.989	0.011
K52.3 Indeterminate colitis	0.000	0.989	0.011
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.989	0.011
E27.2 Addisonian crisis	0.000	0.989	0.011
E84.8 Cystic fibrosis with other manifestations	0.000	0.989	0.011
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.989	0.011
E75.5 Other lipid storage disorders	0.000	0.989	0.011
E73.8 Other lactose intolerance	0.000	0.989	0.011
E73.1 Secondary lactase deficiency	0.000	0.989	0.011
E73.0 Congenital lactase deficiency	0.000	0.989	0.011
E83.5 Disorders of calcium metabolism	0.000	0.989	0.011
E70.3 Albinism	0.000	0.989	0.011
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.989	0.011
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.989	0.011
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.989	0.011
E75.2 Other sphingolipidosis	0.000	0.989	0.011
C43.7 Malignant melanoma of lower limb, including hip	0.010	0.989	0.000
E85.9 Amyloidosis, unspecified	0.000	0.990	0.010
E20.9 Hypoparathyroidism, unspecified	0.001	0.990	0.010
E66.1 Drug-induced obesity	0.000	0.990	0.010
E21.0 Primary hyperparathyroidism	0.000	0.990	0.010
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.990	0.010
E73.9 Lactose intolerance, unspecified	0.000	0.990	0.010
E78.2 Mixed hyperlipidaemia	0.000	0.990	0.010
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.990	0.010
E27.9 Disorder of adrenal gland, unspecified	0.000	0.990	0.009
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.990	0.010
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.990	0.010
E85.3 Secondary systemic amyloidosis	0.000	0.991	0.009
E10.5 With peripheral circulatory complications	0.000	0.991	0.009
M87.9 Osteonecrosis, unspecified	0.000	0.991	0.009
E78.4 Other hyperlipidaemia	0.000	0.991	0.009
E34.5 Androgen resistance syndrome	0.001	0.991	0.008
E34.4 Constitutional tall stature	0.001	0.991	0.008
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.991	0.008
E34.1 Other hypersecretion of intestinal hormones	0.001	0.991	0.008
M87.2 Osteonecrosis due to previous trauma	0.000	0.991	0.009
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.991	0.009
E66.0 Obesity due to excess calories	0.000	0.991	0.008
O47.1 False labour at or after 37 completed weeks of gestation	0.008	0.992	0.000
E34.3 Short stature, not elsewhere classified	0.001	0.992	0.008
S83.2 Tear of meniscus, current	0.000	0.992	0.008
E27.8 Other specified disorders of adrenal gland	0.000	0.992	0.008
M87 Osteonecrosis	0.000	0.992	0.008
E34.9 Endocrine disorder, unspecified	0.001	0.992	0.007
E78.1 Pure hyperglyceridaemia	0.000	0.992	0.007
T79.6 Traumatic ischaemia of muscle	0.000	0.993	0.007
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.993	0.007
O47.0 False labour before 37 completed weeks of gestation	0.007	0.993	0.000
M87.8 Other osteonecrosis	0.000	0.993	0.007
E34.8 Other specified endocrine disorders	0.001	0.993	0.006
E78.3 Hyperchylomicronaemia	0.000	0.993	0.007
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.993	0.007
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.993	0.007
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.993	0.007
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.993	0.007
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.993	0.007
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.993	0.007
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.993	0.007
O47 False labour	0.007	0.993	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.993	0.007
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.000	0.993	0.007
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.993	0.006
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.993	0.006
E78.6 Lipoprotein deficiency	0.000	0.993	0.006
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.994	0.006
F31.0 Bipolar affective disorder, current episode hypomanic	0.006	0.994	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.006	0.994	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.000	0.994	0.006
M87.28 Osteonecrosis due to previous trauma (Other)	0.000	0.994	0.006
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.000	0.994	0.006
M87.24 Osteonecrosis due to previous trauma (Hand)	0.000	0.994	0.006
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.000	0.994	0.006
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.000	0.994	0.006
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.000	0.994	0.006
C53.9 Cervix uteri, unspecified	0.000	0.994	0.006
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.994	0.006
M87.3 Other secondary osteonecrosis	0.000	0.994	0.006
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.994	0.006
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.994	0.006
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.994	0.006
E10.3 With ophthalmic complications	0.000	0.994	0.006
M87.1 Osteonecrosis due to drugs	0.000	0.994	0.006
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.994	0.006
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.994	0.006
E78.8 Other disorders of lipoprotein metabolism	0.000	0.994	0.006
M87.0 Idiopathic aseptic necrosis of bone	0.000	0.994	0.005
F31 Bipolar affective disorder	0.006	0.994	0.000
H54.0 Blindness, both eyes	0.006	0.994	0.000
S83.3 Tear of articular cartilage of knee, current	0.000	0.994	0.006
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.006	0.994	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.006	0.994	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.000	0.995	0.005
M87.88 Other osteonecrosis (Other)	0.000	0.995	0.005
M87.87 Other osteonecrosis (Ankle and foot)	0.000	0.995	0.005
M87.86 Other osteonecrosis (Lower leg)	0.000	0.995	0.005
M87.84 Other osteonecrosis (Hand)	0.000	0.995	0.005
M87.83 Other osteonecrosis (Forearm)	0.000	0.995	0.005
M87.82 Other osteonecrosis (Upper arm)	0.000	0.995	0.005
M87.81 Other osteonecrosis (Shoulder region)	0.000	0.995	0.005
M87.80 Other osteonecrosis (Multiple sites)	0.000	0.995	0.005
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.995	0.005
E28.2 Polycystic ovarian syndrome	0.001	0.995	0.005
O47.9 False labour, unspecified	0.005	0.995	0.000
N30.1 Interstitial cystitis (chronic)	0.005	0.995	0.000
E55.9 Vitamin D deficiency, unspecified	0.001	0.995	0.005
Z88.5 Personal history of allergy to narcotic agent	0.005	0.995	0.000
E34.0 Carcinoid syndrome	0.002	0.995	0.003
E80.5 Crigler-Najjar syndrome	0.000	0.995	0.005
E80.3 Defects of catalase and peroxydase	0.000	0.995	0.005
E80.0 Hereditary erythropoietic porphyria	0.000	0.995	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations