TreeWAS – Variant ID: rs2154401

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	0.992	0.008	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.990	0.010	0.000
I21 Acute myocardial infarction	0.976	0.024	0.000
I24 Other acute ischaemic heart diseases	0.971	0.029	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.964	0.036	0.000
I22 Subsequent myocardial infarction	0.956	0.044	0.000
I20.8 Other forms of angina pectoris	0.952	0.048	0.000
I25.5 Ischaemic cardiomyopathy	0.949	0.051	0.000
I21.9 Acute myocardial infarction, unspecified	0.946	0.054	0.000
I24.8 Other forms of acute ischaemic heart disease	0.901	0.099	0.000
I25.2 Old myocardial infarction	0.891	0.109	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.870	0.130	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.856	0.144	0.000
I22.8 Subsequent myocardial infarction of other sites	0.841	0.159	0.000
I20.1 Angina pectoris with documented spasm	0.821	0.179	0.000
I24.1 Dressler's syndrome	0.779	0.221	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.773	0.227	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.757	0.243	0.000
I25.3 Aneurysm of heart	0.748	0.252	0.000
I23 Certain current complications following acute myocardial infarction	0.732	0.268	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.700	0.300	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.682	0.318	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.659	0.341	0.000
I25.6 Silent myocardial ischaemia	0.648	0.352	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.607	0.393	0.000
I23.8 Other current complications following acute myocardial infarction	0.541	0.459	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.525	0.475	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.525	0.475	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.525	0.475	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.525	0.475	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.525	0.475	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.525	0.475	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.525	0.475	0.000
I20.0 Unstable angina	0.450	0.550	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.405	0.594	0.000
I25.4 Coronary artery aneurysm	0.401	0.598	0.001
I25.0 Atherosclerotic cardiovascular disease, so described	0.354	0.645	0.001
I21.4 Acute subendocardial myocardial infarction	0.261	0.739	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.852	0.148
I21.1 Acute transmural myocardial infarction of inferior wall	0.042	0.958	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.038	0.962	0.000
Z95.0 Presence of cardiac pacemaker	0.031	0.969	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.028	0.972	0.000
Z95.1 Presence of aortocoronary bypass graft	0.028	0.972	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.027	0.973	0.000
M25.4 Effusion of joint	0.000	0.978	0.022
M25.44 Effusion of joint (Hand)	0.000	0.983	0.017
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.983	0.017
M25.49 Effusion of joint (Site unspecified)	0.000	0.984	0.016
M25.48 Effusion of joint (Other)	0.000	0.984	0.016
M25.42 Effusion of joint (Upper arm)	0.000	0.984	0.016
M25.43 Effusion of joint (Forearm)	0.000	0.984	0.016
S01.9 Open wound of head, part unspecified	0.016	0.984	0.000
M25.41 Effusion of joint (Shoulder region)	0.000	0.986	0.014
M25.40 Effusion of joint (Multiple sites)	0.000	0.987	0.012
R86.8 Other abnormal findings	0.000	0.989	0.011
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.990	0.010
S62.30 Fracture of other metacarpal bone (closed)	0.009	0.991	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.991	0.009
S82.60 Fracture of lateral malleolus (closed)	0.008	0.992	0.000
D68.2 Hereditary deficiency of other clotting factors	0.008	0.992	0.000
Z95.3 Presence of xenogenic heart valve	0.008	0.992	0.000
R86 Abnormal findings in specimens from male genital organs	0.000	0.992	0.008
Z95.8 Presence of other cardiac and vascular implants and grafts	0.008	0.992	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.993	0.007
R86.9 Unspecified abnormal finding	0.000	0.993	0.007
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.007	0.993	0.000
I08 Multiple valve diseases	0.000	0.993	0.007
M25.47 Effusion of joint (Ankle and foot)	0.000	0.993	0.006
S82.6 Fracture of lateral malleolus	0.006	0.994	0.000
F40.2 Specific (isolated) phobias	0.000	0.994	0.006
R86.0 Abnormal level of enzymes	0.000	0.994	0.006
Z63.4 Disappearance and death of family member	0.000	0.994	0.006
R86.6 Abnormal cytological findings	0.000	0.994	0.006
R86.5 Abnormal microbiological findings	0.000	0.994	0.006
R86.4 Abnormal immunological findings	0.000	0.994	0.006
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.000	0.994	0.006
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.000	0.994	0.006
R86.1 Abnormal level of hormones	0.000	0.994	0.006
D09.0 Bladder	0.006	0.994	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.994	0.006
Z63 Other problems related to primary support group, including family circumstances	0.000	0.994	0.006
S82.61 Fracture of lateral malleolus (open)	0.005	0.994	0.000
R86.7 Abnormal histological findings	0.000	0.994	0.005
Z63.8 Other specified problems related to primary support group	0.000	0.995	0.005
Z63.0 Problems in relationship with spouse or partner	0.000	0.995	0.005
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.995	0.005
S72.20 Subtrochanteric fracture (closed)	0.005	0.995	0.000
Z63.6 Dependent relative needing care at home	0.000	0.995	0.005
I08.9 Multiple valve disease, unspecified	0.000	0.995	0.004
D68 Other coagulation defects	0.005	0.995	0.000
N60.2 Fibroadenosis of breast	0.000	0.996	0.004
O44.1 Placenta praevia with haemorrhage	0.000	0.996	0.004
S82.20 Fracture of shaft of tibia (closed)	0.004	0.996	0.000
Z57.2 Occupational exposure to dust	0.000	0.996	0.004
Z63.9 Problem related to primary support group, unspecified	0.000	0.996	0.004
Z63.3 Absence of family member	0.000	0.996	0.004
Z63.2 Inadequate family support	0.000	0.996	0.004
Z63.1 Problems in relationship with parents and in-laws	0.000	0.996	0.004
J10.0 Influenza with pneumonia, influenza virus identified	0.000	0.996	0.004
F40.0 Agoraphobia	0.000	0.996	0.004
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.996	0.004
F40 Phobic anxiety disorders	0.000	0.996	0.004
S62.3 Fracture of other metacarpal bone	0.004	0.996	0.000
S82 Fracture of lower leg, including ankle	0.004	0.996	0.000
D68.0 Von Willebrand's disease	0.004	0.996	0.000
S82.2 Fracture of shaft of tibia	0.004	0.996	0.000
D68.5 Primary Thrombophilia	0.004	0.996	0.000
Z58.8 Other problems related to physical environment	0.000	0.996	0.004
Z58 Problems related to physical environment	0.000	0.996	0.004
D68.8 Other specified coagulation defects	0.004	0.996	0.000
O44 Placenta praevia	0.000	0.996	0.004
Q21 Congenital malformations of cardiac septa	0.000	0.996	0.004
Z58.5 Exposure to other pollution	0.000	0.996	0.004
S72.2 Subtrochanteric fracture	0.004	0.996	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.996	0.004
Z57.3 Occupational exposure to other air contaminants	0.000	0.996	0.004
D68.4 Acquired coagulation factor deficiency	0.004	0.996	0.000
Z63.7 Other stressful life events affecting family and household	0.000	0.996	0.004
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.996	0.004
Z57 Occupational exposure to risk-factors	0.000	0.996	0.004
S72.30 Fracture of shaft of femur (closed)	0.004	0.996	0.000
Q21.0 Ventricular septal defect	0.000	0.996	0.004
D68.9 Coagulation defect, unspecified	0.004	0.996	0.000
S82.3 Fracture of lower end of tibia	0.004	0.996	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.004	0.996	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.004	0.996	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.003	0.996	0.000
Q21.1 Atrial septal defect	0.000	0.997	0.003
Z63.5 Disruption of family by separation and divorce	0.000	0.997	0.003
I78.1 Naevus, nonneoplastic	0.000	0.997	0.003
S82.9 Fracture of lower leg, part unspecified	0.003	0.997	0.000
J10 Influenza due to identified influenza virus	0.000	0.997	0.003
D68.1 Hereditary factor XI deficiency	0.003	0.997	0.000
I08.8 Other multiple valve diseases	0.000	0.997	0.003
S81.8 Open wound of other parts of lower leg	0.003	0.997	0.000
K38.1 Appendicular concretions	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.003	0.997	0.000
Q21.3 Tetralogy of Fallot	0.000	0.997	0.003
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.000	0.997	0.003
M48.06 Spinal stenosis (Lumbar region)	0.003	0.997	0.000
S82.8 Fractures of other parts of lower leg	0.003	0.997	0.000
K38 Other diseases of appendix	0.003	0.997	0.000
S72.40 Fracture of lower end of femur (closed)	0.003	0.997	0.000
Z58.1 Exposure to air pollution	0.000	0.997	0.003
S72.3 Fracture of shaft of femur	0.003	0.997	0.000
S82.30 Fracture of lower end of tibia (closed)	0.003	0.997	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
S62.31 Fracture of other metacarpal bone (open)	0.003	0.997	0.000
F40.1 Social phobias	0.000	0.997	0.003
S82.80 Fractures of other parts of lower leg (closed)	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.997	0.003
S82.7 Multiple fractures of lower leg	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.000	0.997	0.003
K38.9 Disease of appendix, unspecified	0.003	0.997	0.000
F40.8 Other phobic anxiety disorders	0.000	0.997	0.003
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.003	0.997	0.000
F40.9 Phobic anxiety disorder, unspecified	0.000	0.997	0.003
I69.1 Sequelae of intracerebral haemorrhage	0.003	0.997	0.000
Z58.9 Problem related to physical environment, unspecified	0.000	0.997	0.003
Z58.6 Inadequate drinking-water supply	0.000	0.997	0.003
Z58.4 Exposure to radiation	0.000	0.997	0.003
Z58.3 Exposure to soil pollution	0.000	0.997	0.003
Z58.2 Exposure to water pollution	0.000	0.997	0.003
Z58.0 Exposure to noise	0.000	0.997	0.003
S82.91 Fracture of lower leg, part unspecified (open)	0.003	0.997	0.000
Q21.8 Other congenital malformations of cardiac septa	0.000	0.997	0.003
Q21.4 Aortopulmonary septal defect	0.000	0.997	0.003
Q21.2 Atrioventricular septal defect	0.000	0.997	0.003
Z61 Problems related to negative life events in childhood	0.000	0.997	0.003
K38.8 Other specified diseases of appendix	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.000	0.997	0.003
S72.21 Subtrochanteric fracture (open)	0.003	0.997	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.997	0.003
S72 Fracture of femur	0.003	0.997	0.000
S72.4 Fracture of lower end of femur	0.003	0.997	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.997	0.003
Z57.7 Occupational exposure to vibration	0.000	0.997	0.003
Z57.6 Occupational exposure to extreme temperature	0.000	0.997	0.003
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.997	0.003
Z57.1 Occupational exposure to radiation	0.000	0.997	0.003
Z57.0 Occupational exposure to noise	0.000	0.997	0.003
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.997	0.003
S82.31 Fracture of lower end of tibia (open)	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.003	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.003	0.997	0.000
D09 Carcinoma in situ of other and unspecified sites	0.003	0.997	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.003	0.997	0.000
K38.2 Diverticulum of appendix	0.003	0.997	0.000
S82.1 Fracture of upper end of tibia	0.003	0.997	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.000	0.997	0.003
S82.90 Fracture of lower leg, part unspecified (closed)	0.003	0.997	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.000	0.997	0.003
K51.2 Ulcerative (chronic) proctitis	0.000	0.997	0.003
Q27.8 Other specified congenital malformations of peripheral vascular system	0.000	0.997	0.003
S82.5 Fracture of medial malleolus	0.003	0.997	0.000
Z58.7 Exposure to tobacco smoke	0.000	0.997	0.003
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.003	0.997	0.000
D68.6 Other Thrombophilia	0.003	0.997	0.000
Z62 Other problems related to upbringing	0.000	0.997	0.003
Z55 Problems related to education and literacy	0.000	0.997	0.003
S82.21 Fracture of shaft of tibia (open)	0.003	0.997	0.000
S82.86 Maisonneuve's fracture	0.003	0.997	0.000
K38.3 Fistula of appendix	0.003	0.997	0.000
S82.0 Fracture of patella	0.003	0.997	0.000
G30.9 Alzheimer's disease, unspecified	0.003	0.997	0.000
S72.31 Fracture of shaft of femur (open)	0.002	0.997	0.000
R30.9 Painful micturition, unspecified	0.000	0.997	0.003
Z65 Problems related to other psychosocial circumstances	0.000	0.997	0.002
K38.0 Hyperplasia of appendix	0.002	0.997	0.000
Z64 Problems related to certain psychosocial circumstances	0.000	0.997	0.002
S82.71 Multiple fractures of lower leg (open)	0.002	0.997	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.997	0.002
Q27.4 Congenital phlebectasia	0.000	0.997	0.002
Q27.2 Other congenital malformations of renal artery	0.000	0.997	0.002
Q27.1 Congenital renal artery stenosis	0.000	0.997	0.002
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.000	0.997	0.002
S82.70 Multiple fractures of lower leg (closed)	0.002	0.997	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.997	0.002
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.002
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
S82.11 Fracture of upper end of tibia (open)	0.002	0.998	0.000
S72.9 Fracture of femur, part unspecified	0.002	0.998	0.000
Z61.9 Negative life events in childhood, unspecified	0.000	0.998	0.002
Z61.8 Other negative life events in childhood	0.000	0.998	0.002
Z61.7 Personal frightening experience in childhood	0.000	0.998	0.002
Z61.6 Problems related to alleged physical abuse of child	0.000	0.998	0.002
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.000	0.998	0.002
Z61.3 Events resulting in loss of self-esteem in childhood	0.000	0.998	0.002
Z61.2 Altered pattern of family relationships in childhood	0.000	0.998	0.002
Z61.1 Removal from home in childhood	0.000	0.998	0.002
Z61.0 Loss of love relationship in childhood	0.000	0.998	0.002
S72.7 Multiple fractures of femur	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.998	0.002
S72.8 Fractures of other parts of femur	0.002	0.998	0.000
D09.9 Carcinoma in situ, unspecified	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
K37 Unspecified appendicitis	0.002	0.998	0.000
D09.3 Thyroid and other endocrine glands	0.002	0.998	0.000
D09.2 Eye	0.002	0.998	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
S82.01 Fracture of patella (open)	0.002	0.998	0.000
S82.4 Fracture of fibula alone	0.002	0.998	0.000
K36 Other appendicitis	0.002	0.998	0.000
D09.7 Carcinoma in situ of other specified sites	0.002	0.998	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
D09.1 Other and unspecified urinary organs	0.002	0.998	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.002	0.998	0.000
C71.4 Occipital lobe	0.000	0.998	0.002
Z55.9 Problems relating to education and literacy, unspecified	0.000	0.998	0.002
Z55.8 Other problems relating to education and literacy	0.000	0.998	0.002
Z55.4 Educational maladjustment and discord with teachers and classmates	0.000	0.998	0.002
Z55.3 Underachievement in school	0.000	0.998	0.002
Z55.2 Failed examinations	0.000	0.998	0.002
Z55.1 Schooling unavailable and unattainable	0.000	0.998	0.002
Z55.0 Illiteracy and low-level literacy	0.000	0.998	0.002
Z62.9 Problem related to upbringing, unspecified	0.000	0.998	0.002
Z62.8 Other specified problems related to upbringing	0.000	0.998	0.002
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.000	0.998	0.002
Z62.5 Other problems related to neglect in upbringing	0.000	0.998	0.002
Z62.4 Emotional neglect of child	0.000	0.998	0.002
Z62.3 Hostility towards and scapegoating of child	0.000	0.998	0.002
Z62.2 Institutional upbringing	0.000	0.998	0.002
Z62.1 Parental overprotection	0.000	0.998	0.002
Z62.0 Inadequate parental supervision and control	0.000	0.998	0.002
K35-K38 Diseases of appendix	0.002	0.998	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.998	0.002
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.998	0.002
V48.4 Person injured while boarding or alighting	0.002	0.998	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.000	0.998	0.002
Z65.8 Other specified problems related to psychosocial circumstances	0.000	0.998	0.002
Z65.5 Exposure to disaster, war and other hostilities	0.000	0.998	0.002
Z65.4 Victim of crime and terrorism	0.000	0.998	0.002
Z65.2 Problems related to release from prison	0.000	0.998	0.002
Z65.1 Imprisonment and other incarceration	0.000	0.998	0.002
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.000	0.998	0.002
Z64.4 Discord with counsellors	0.000	0.998	0.002
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.000	0.998	0.002
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.000	0.998	0.002
Z64.1 Problems related to multiparity	0.000	0.998	0.002
S82.81 Fractures of other parts of lower leg (open)	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.000	0.998	0.002
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.998	0.002
S82.51 Fracture of medial malleolus (open)	0.002	0.998	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.998	0.002
Q26 Congenital malformations of great veins	0.000	0.998	0.002
C71.3 Parietal lobe	0.000	0.998	0.002
D07.5 Prostate	0.002	0.998	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.002	0.998	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
Z60.8 Other problems related to social environment	0.000	0.998	0.002
Q20 Congenital malformations of cardiac chambers and connexions	0.000	0.998	0.002
S72.91 Fracture of femur, part unspecified (open)	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.000	0.998	0.002
Z65.3 Problems related to other legal circumstances	0.000	0.998	0.002
Z93.4 Other artificial openings of gastro-intestinal tract status	0.002	0.998	0.000
H71 Cholesteatoma of middle ear	0.002	0.998	0.000
S72.71 Multiple fractures of femur (open)	0.002	0.998	0.000
S72.70 Multiple fractures of femur (closed)	0.002	0.998	0.000
O62.2 Other uterine inertia	0.000	0.998	0.002
O75.8 Other specified complications of labour and delivery	0.000	0.998	0.002
S72.81 Fractures of other parts of femur (open)	0.002	0.998	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
Z64.0 Problems related to unwanted pregnancy	0.000	0.998	0.002
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.000	0.998	0.002
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
Z56 Problems related to employment and unemployment	0.000	0.998	0.002
S72.80 Fractures of other parts of femur (closed)	0.002	0.998	0.000
T21.2 Burn of second degree of trunk	0.002	0.998	0.000
T21 Burn and corrosion of trunk	0.002	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.000	0.998	0.002
S82.41 Fracture of fibula alone (open)	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.000	0.998	0.002
S81 Open wound of lower leg	0.002	0.998	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.998	0.002
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
D07.1 Vulva	0.002	0.998	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
S72.41 Fracture of lower end of femur (open)	0.002	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.998	0.002
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
V48 Car occupant injured in noncollision transport accident	0.002	0.998	0.000
F45.2 Hypochondriacal disorder	0.000	0.998	0.002
H35.7 Separation of retinal layers	0.000	0.998	0.002
Q23.3 Congenital mitral insufficiency	0.000	0.998	0.002
Z59 Problems related to housing and economic circumstances	0.001	0.998	0.001
S72.11 Pertrochanteric fracture (open)	0.002	0.998	0.000
C25.2 Tail of pancreas	0.000	0.998	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.998	0.002
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.998	0.002
Q23.4 Hypoplastic left heart syndrome	0.000	0.998	0.002
Q23.2 Congenital mitral stenosis	0.000	0.998	0.002
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.001	0.998	0.000
Q25 Congenital malformations of great arteries	0.000	0.998	0.002
M06.32 Rheumatoid nodule (Upper arm)	0.002	0.998	0.000
T23.1 Burn of first degree of wrist and hand	0.002	0.998	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.002	0.998	0.000
Z60 Problems related to social environment	0.000	0.998	0.002
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
F45.9 Somatoform disorder, unspecified	0.000	0.998	0.002
Q24.5 Malformation of coronary vessels	0.000	0.998	0.002
V48.6 Passenger injured in traffic accident	0.002	0.998	0.000
V49.6 Unspecified car occupant injured in collision with other and unspecified motor vehicles in traffic accident	0.002	0.998	0.000
Z48.0 Attention to surgical dressings and sutures	0.002	0.998	0.000
Q24.6 Congenital heart block	0.000	0.998	0.002
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.000	0.998	0.002
T21.3 Burn of third degree of trunk	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
Q24.3 Pulmonary infundibular stenosis	0.000	0.998	0.002
Q24.2 Cor triatriatum	0.000	0.998	0.002
Q24.1 Levocardia	0.000	0.998	0.002
Q25.3 Stenosis of aorta	0.000	0.998	0.002
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.000	0.998	0.002
Q26.9 Congenital malformation of great vein, unspecified	0.000	0.998	0.002
Q26.8 Other congenital malformations of great veins	0.000	0.998	0.002
Q26.6 Portal vein-hepatic artery fistula	0.000	0.998	0.002
Q26.5 Anomalous portal venous connexion	0.000	0.998	0.002
Q26.3 Partial anomalous pulmonary venous connexion	0.000	0.998	0.002
Q26.2 Total anomalous pulmonary venous connexion	0.000	0.998	0.002
Q26.1 Persistent left superior vena cava	0.000	0.998	0.002
Q26.0 Congenital stenosis of vena cava	0.000	0.998	0.002
T23.3 Burn of third degree of wrist and hand	0.002	0.998	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.002	0.998	0.000
C71.2 Temporal lobe	0.000	0.998	0.002
M19.1 Posttraumatic arthrosis of other joints	0.000	0.998	0.002
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.000	0.998	0.002
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.000	0.998	0.002
Q20.6 Isomerism of atrial appendages	0.000	0.998	0.002
Q20.5 Discordant atrioventricular connexion	0.000	0.998	0.002
Q20.4 Double inlet ventricle	0.000	0.998	0.002
Q20.3 Discordant ventriculoarterial connexion	0.000	0.998	0.002
Q20.2 Double outlet left ventricle	0.000	0.998	0.002
Q20.1 Double outlet right ventricle	0.000	0.998	0.002
Q20.0 Common arterial trunk	0.000	0.998	0.002
I09 Other rheumatic heart diseases	0.000	0.998	0.002
T23 Burn and corrosion of wrist and hand	0.002	0.998	0.000
M47.9 Spondylosis, unspecified	0.000	0.998	0.002
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.998	0.002
V49.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.000	0.998	0.002
C70.0 Cerebral meninges	0.000	0.998	0.002
D07.2 Vagina	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
V49.0 Driver injured in collision with other and unspecified motor vehicles in nontraffic accident	0.002	0.998	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.002	0.998	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
Z56.5 Uncongenial work	0.000	0.998	0.001
Z56.4 Discord with boss and workmates	0.000	0.998	0.001
Z56.2 Threat of job loss	0.000	0.998	0.001
Z56.1 Change of job	0.000	0.998	0.001
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.001	0.998	0.000
C69.0 Conjunctiva	0.000	0.998	0.002
F45.0 Somatisation disorder	0.000	0.998	0.002
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.000	0.998	0.001
Q22.8 Other congenital malformations of tricuspid valve	0.000	0.998	0.001
Q22.6 Hypoplastic right heart syndrome	0.000	0.998	0.001
Q22.4 Congenital tricuspid stenosis	0.000	0.998	0.001
Q22.3 Other congenital malformations of pulmonary valve	0.000	0.998	0.001
Q22.2 Congenital pulmonary valve insufficiency	0.000	0.998	0.001
Q22.0 Pulmonary valve atresia	0.000	0.998	0.001
S61.1 Open wound of finger(s) with damage to nail	0.002	0.998	0.000
T21.7 Corrosion of third degree of trunk	0.002	0.998	0.000
T21.6 Corrosion of second degree of trunk	0.002	0.998	0.000
T21.5 Corrosion of first degree of trunk	0.002	0.998	0.000
T21.4 Corrosion of unspecified degree of trunk	0.002	0.998	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.000	0.998	0.002
H72.8 Other perforations of tympanic membrane	0.000	0.998	0.002
I09.9 Rheumatic heart disease, unspecified	0.000	0.998	0.002
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.001	0.998	0.000
V48.9 Unspecified car occupant injured in traffic accident	0.002	0.998	0.000
Z59.1 Inadequate housing	0.001	0.998	0.000
F45 Somatoform disorders	0.000	0.998	0.002
I06 Rheumatic aortic valve diseases	0.000	0.998	0.001
T25 Burn and corrosion of ankle and foot	0.002	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.998	0.002
C71.6 Cerebellum	0.000	0.998	0.001
D07.4 Penis	0.002	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.000	0.998	0.001
Q24.0 Dextrocardia	0.000	0.998	0.001
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.001	0.998	0.000
V48.5 Driver injured in traffic accident	0.001	0.998	0.000
V48.7 Person on outside of vehicle injured in traffic accident	0.001	0.998	0.000
V48.3 Unspecified car occupant injured in nontraffic accident	0.001	0.998	0.000
V48.2 Person on outside of vehicle injured in nontraffic accident	0.001	0.998	0.000
V48.1 Passenger injured in nontraffic accident	0.001	0.998	0.000
Z59.7 Insufficient social insurance and welfare support	0.001	0.998	0.001
Z59.6 Low income	0.001	0.998	0.001
Z59.5 Extreme poverty	0.001	0.998	0.001
Z59.3 Problems related to living in residential institution	0.001	0.998	0.001
Z59.2 Discord with neighbours, lodgers and landlord	0.001	0.998	0.001
C25.9 Pancreas, unspecified	0.000	0.998	0.002
C71.7 Brain stem	0.000	0.998	0.001
Q25.9 Congenital malformation of great arteries, unspecified	0.000	0.998	0.001
Q25.8 Other congenital malformations of great arteries	0.000	0.998	0.001
Q25.5 Atresia of pulmonary artery	0.000	0.998	0.001
Q25.2 Atresia of aorta	0.000	0.998	0.001
T21.0 Burn of unspecified degree of trunk	0.001	0.998	0.000
Z56.3 Stressful work schedule	0.000	0.998	0.001
Z59.4 Lack of adequate food	0.001	0.998	0.001
C70 Malignant neoplasm of meninges	0.000	0.998	0.002
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.998	0.001
C69.9 Eye, unspecified	0.000	0.998	0.002
Q25.4 Other congenital malformations of aorta	0.000	0.998	0.001
Q25.1 Coarctation of aorta	0.000	0.998	0.001
Z56.7 Other and unspecified problems related to employment	0.000	0.998	0.001
Z60.5 Target of perceived adverse discrimination and persecution	0.000	0.998	0.001
Z60.4 Social exclusion and rejection	0.000	0.998	0.001
Z60.3 Acculturation difficulty	0.000	0.998	0.001
Z60.1 Atypical parenting situation	0.000	0.998	0.001
Z60.0 Problems of adjustment to life-cycle transitions	0.000	0.998	0.001
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.000	0.998	0.001
C71.9 Brain, unspecified	0.000	0.998	0.002
F45.4 Persistent somatoform pain disorder	0.000	0.998	0.001
I34.0 Mitral (valve) insufficiency	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.002	0.998	0.000
L03.3 Cellulitis of trunk	0.000	0.998	0.002
Q22.5 Ebstein's anomaly	0.000	0.998	0.001
Q25.7 Other congenital malformations of pulmonary artery	0.000	0.998	0.001
V48.0 Driver injured in nontraffic accident	0.001	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
D07.6 Other and unspecified male genital organs	0.001	0.998	0.000
D07.3 Other and unspecified female genital organs	0.001	0.998	0.000
G93.6 Cerebral oedema	0.000	0.998	0.002
R87.7 Abnormal histological findings	0.000	0.998	0.002
T21.1 Burn of first degree of trunk	0.001	0.998	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.001	0.998	0.000
W25.9 Unspecified place	0.002	0.998	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.000	0.998	0.001
M19.18 Post-traumatic arthrosis of other joints (Other)	0.000	0.998	0.001
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.000	0.998	0.001
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.000	0.998	0.001
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.000	0.998	0.001
C69.3 Choroid	0.000	0.998	0.001
I09.8 Other specified rheumatic heart diseases	0.000	0.998	0.001
I09.2 Chronic rheumatic pericarditis	0.000	0.998	0.001
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.998	0.001
I09.0 Rheumatic myocarditis	0.000	0.998	0.001
K35.2 Acute appendicitis with generalized peritonitis	0.002	0.998	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations