TreeWAS – Variant ID: rs2188561

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M10.99 Gout, unspecified (Site unspecified)	0.114	0.886	0.000
M10.9 Gout, unspecified	0.067	0.933	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.053	0.947	0.000
M10.96 Gout, unspecified (Lower leg)	0.050	0.950	0.000
M10.90 Gout, unspecified (Multiple sites)	0.049	0.951	0.000
M10.93 Gout, unspecified (Forearm)	0.049	0.951	0.000
M10.98 Gout, unspecified (Other)	0.048	0.951	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.048	0.951	0.000
M10.91 Gout, unspecified (Shoulder region)	0.048	0.951	0.000
M10.94 Gout, unspecified (Hand)	0.046	0.954	0.000
M10.92 Gout, unspecified (Upper arm)	0.042	0.958	0.000
M10 Gout	0.032	0.968	0.000
S92 Fracture of foot, except ankle	0.026	0.974	0.000
S92.4 Fracture of great toe	0.025	0.975	0.000
S92.41 Fracture of great toe (open)	0.024	0.976	0.000
M10.4 Other secondary gout	0.023	0.977	0.000
M10.3 Gout due to impairment of renal function	0.023	0.977	0.000
M10.2 Drug-induced gout	0.023	0.977	0.000
M10.1 Lead-induced gout	0.023	0.977	0.000
S92.5 Fracture of other toe	0.023	0.977	0.000
M10.0 Idiopathic gout	0.023	0.977	0.000
S90-S99 Injuries to the ankle and foot	0.023	0.977	0.000
S92.2 Fracture of other tarsal bone(s)	0.023	0.977	0.000
S92.51 Fracture of other toe (open)	0.022	0.978	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.021	0.979	0.000
S92.40 Fracture of great toe (closed)	0.020	0.980	0.000
S91 Open wound of ankle and foot	0.020	0.980	0.000
S92.3 Fracture of metatarsal bone	0.020	0.980	0.000
S90 Superficial injury of ankle and foot	0.019	0.981	0.000
S92.7 Multiple fractures of foot	0.019	0.981	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.019	0.981	0.000
S92.9 Fracture of foot, unspecified	0.018	0.981	0.000
S91.3 Open wound of other parts of foot	0.018	0.982	0.000
S97 Crushing injury of ankle and foot	0.018	0.982	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.018	0.982	0.000
M10.09 Idiopathic gout (Site unspecified)	0.018	0.982	0.000
S92.0 Fracture of calcaneus	0.018	0.982	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.018	0.982	0.000
S92.50 Fracture of other toe (closed)	0.017	0.983	0.000
M10.19 Lead-induced gout (Site unspecified)	0.017	0.983	0.000
M10.18 Lead-induced gout (Other)	0.017	0.983	0.000
M10.17 Lead-induced gout (Ankle and foot)	0.017	0.983	0.000
M10.16 Lead-induced gout (Lower leg)	0.017	0.983	0.000
M10.15 Lead-induced gout (Pelvic region and thigh)	0.017	0.983	0.000
M10.14 Lead-induced gout (Hand)	0.017	0.983	0.000
M10.13 Lead-induced gout (Forearm)	0.017	0.983	0.000
M10.12 Lead-induced gout (Upper arm)	0.017	0.983	0.000
M10.11 Lead-induced gout (Shoulder region)	0.017	0.983	0.000
M10.10 Lead-induced gout (Multiple sites)	0.017	0.983	0.000
M10.29 Drug-induced gout (Site unspecified)	0.017	0.983	0.000
M10.28 Drug-induced gout (Other)	0.017	0.983	0.000
M10.27 Drug-induced gout (Ankle and foot)	0.017	0.983	0.000
M10.26 Drug-induced gout (Lower leg)	0.017	0.983	0.000
M10.25 Drug-induced gout (Pelvic region and thigh)	0.017	0.983	0.000
M10.24 Drug-induced gout (Hand)	0.017	0.983	0.000
M10.23 Drug-induced gout (Forearm)	0.017	0.983	0.000
M10.22 Drug-induced gout (Upper arm)	0.017	0.983	0.000
M10.21 Drug-induced gout (Shoulder region)	0.017	0.983	0.000
M10.20 Drug-induced gout (Multiple sites)	0.017	0.983	0.000
M10.39 Gout due to impairment of renal function (Site unspecified)	0.017	0.983	0.000
M10.38 Gout due to impairment of renal function (Other)	0.017	0.983	0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.017	0.983	0.000
M10.36 Gout due to impairment of renal function (Lower leg)	0.017	0.983	0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.017	0.983	0.000
M10.34 Gout due to impairment of renal function (Hand)	0.017	0.983	0.000
M10.33 Gout due to impairment of renal function (Forearm)	0.017	0.983	0.000
M10.32 Gout due to impairment of renal function (Upper arm)	0.017	0.983	0.000
M10.31 Gout due to impairment of renal function (Shoulder region)	0.017	0.983	0.000
M10.30 Gout due to impairment of renal function (Multiple sites)	0.017	0.983	0.000
M10.49 Other secondary gout (Site unspecified)	0.017	0.983	0.000
M10.48 Other secondary gout (Other)	0.017	0.983	0.000
M10.47 Other secondary gout (Ankle and foot)	0.017	0.983	0.000
M10.46 Other secondary gout (Lower leg)	0.017	0.983	0.000
M10.45 Other secondary gout (Pelvic region and thigh)	0.017	0.983	0.000
M10.44 Other secondary gout (Hand)	0.017	0.983	0.000
M10.43 Other secondary gout (Forearm)	0.017	0.983	0.000
M10.42 Other secondary gout (Upper arm)	0.017	0.983	0.000
M10.41 Other secondary gout (Shoulder region)	0.017	0.983	0.000
M10.40 Other secondary gout (Multiple sites)	0.017	0.983	0.000
M10.08 Idiopathic gout (Other)	0.017	0.983	0.000
M10.06 Idiopathic gout (Lower leg)	0.017	0.983	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.017	0.983	0.000
M10.04 Idiopathic gout (Hand)	0.017	0.983	0.000
M10.03 Idiopathic gout (Forearm)	0.017	0.983	0.000
M10.02 Idiopathic gout (Upper arm)	0.017	0.983	0.000
M10.01 Idiopathic gout (Shoulder region)	0.017	0.983	0.000
M10.00 Idiopathic gout (Multiple sites)	0.017	0.983	0.000
S98 Traumatic amputation of ankle and foot	0.017	0.983	0.000
S95 Injury of blood vessels at ankle and foot level	0.017	0.983	0.000
S94 Injury of nerves at ankle and foot level	0.017	0.983	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.016	0.983	0.000
S99 Other and unspecified injuries of ankle and foot	0.016	0.984	0.000
S92.1 Fracture of talus	0.016	0.984	0.000
S92.30 Fracture of metatarsal bone (closed)	0.016	0.984	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.015	0.984	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.015	0.985	0.000
S90.1 Contusion of toe(s) without damage to nail	0.015	0.985	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.015	0.985	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.015	0.985	0.000
S90.3 Contusion of other and unspecified parts of foot	0.015	0.985	0.000
S91.7 Multiple open wounds of ankle and foot	0.014	0.985	0.000
S91.2 Open wound of toe(s) with damage to nail	0.014	0.985	0.000
S92.31 Fracture of metatarsal bone (open)	0.014	0.985	0.000
S92.70 Multiple fractures of foot (closed)	0.014	0.986	0.000
S93.0 Dislocation of ankle joint	0.014	0.986	0.000
S90.0 Contusion of ankle	0.014	0.986	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.014	0.986	0.000
S90.2 Contusion of toe(s) with damage to nail	0.014	0.986	0.000
S91.1 Open wound of toe(s) without damage to nail	0.014	0.986	0.000
S91.0 Open wound of ankle	0.014	0.986	0.000
S92.71 Multiple fractures of foot (open)	0.014	0.986	0.000
S93.4 Sprain and strain of ankle	0.014	0.986	0.000
S93.5 Sprain and strain of toe(s)	0.014	0.986	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.014	0.986	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.014	0.986	0.000
S92.91 Fracture of foot, unspecified (open)	0.013	0.986	0.000
S92.90 Fracture of foot, unspecified (closed)	0.013	0.986	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.013	0.986	0.000
S97.1 Crushing injury of toe(s)	0.013	0.987	0.000
S97.0 Crushing injury of ankle	0.013	0.987	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.013	0.987	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.013	0.987	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.013	0.987	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.013	0.987	0.000
S92.01 Fracture of calcaneus (open)	0.013	0.987	0.000
S93.1 Dislocation of toe(s)	0.013	0.987	0.000
S99.8 Other specified injuries of ankle and foot	0.013	0.987	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.012	0.988	0.000
S94.8 Injury of other nerves at ankle and foot level	0.012	0.988	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.012	0.988	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.012	0.988	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.012	0.988	0.000
S94.1 Injury of medial plantar nerve	0.012	0.988	0.000
S94.0 Injury of lateral plantar nerve	0.012	0.988	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.012	0.988	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.012	0.988	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.012	0.988	0.000
S95.2 Injury of dorsal vein of foot	0.012	0.988	0.000
S95.1 Injury of plantar artery of foot	0.012	0.988	0.000
S95.0 Injury of dorsal artery of foot	0.012	0.988	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.012	0.988	0.000
S98.3 Traumatic amputation of other parts of foot	0.012	0.988	0.000
S98.2 Traumatic amputation of two or more toes	0.012	0.988	0.000
S98.1 Traumatic amputation of one toe	0.012	0.988	0.000
S98.0 Traumatic amputation of foot at ankle level	0.012	0.988	0.000
S99.7 Multiple injuries of ankle and foot	0.012	0.988	0.000
S92.00 Fracture of calcaneus (closed)	0.012	0.988	0.000
S92.11 Fracture of talus (open)	0.011	0.988	0.000
C50.2 Upper-inner quadrant of breast	0.000	0.989	0.011
S99.9 Unspecified injury of ankle and foot	0.011	0.989	0.000
S93.40 Sprain of unspecified ligament of ankle	0.010	0.990	0.000
N03.9 Unspecified	0.010	0.990	0.000
S90.8 Other superficial injuries of ankle and foot	0.010	0.990	0.000
K14.8 Other diseases of tongue	0.000	0.991	0.009
S92.10 Fracture of talus (closed)	0.009	0.991	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.008	0.992	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.008	0.992	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.008	0.992	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.008	0.992	0.000
S70-S79 Injuries to the hip and thigh	0.008	0.992	0.000
S72 Fracture of femur	0.008	0.992	0.000
K81.9 Cholecystitis, unspecified	0.000	0.992	0.008
O48 Prolonged pregnancy	0.000	0.992	0.008
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.007	0.993	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.007	0.993	0.000
S72.2 Subtrochanteric fracture	0.007	0.993	0.000
M05-M14 Inflammatory polyarthropathies	0.007	0.993	0.000
S73.0 Dislocation of hip	0.007	0.993	0.000
T45.0 Antiallergic and antiemetic drugs	0.007	0.993	0.000
N03 Chronic nephritic syndrome	0.007	0.993	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.007	0.993	0.000
S72.20 Subtrochanteric fracture (closed)	0.007	0.993	0.000
S72.1 Pertrochanteric fracture	0.007	0.993	0.000
S71 Open wound of hip and thigh	0.007	0.993	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
S72.10 Pertrochanteric fracture (closed)	0.007	0.993	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.007	0.993	0.000
S72.3 Fracture of shaft of femur	0.007	0.993	0.000
M14 Arthropathies in other diseases classified elsewhere	0.007	0.993	0.000
S72.4 Fracture of lower end of femur	0.007	0.993	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.993	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.006	0.993	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.007	0.993	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.993	0.000
T45.5 Anticoagulants	0.006	0.993	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.006	0.993	0.000
Z00.0 General medical examination	0.006	0.994	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.006	0.994	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.006	0.994	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.006	0.994	0.000
M54.36 Sciatica (Lumbar region)	0.000	0.994	0.006
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.006	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.006	0.994	0.000
J93.1 Other spontaneous pneumothorax	0.000	0.994	0.006
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.006	0.994	0.000
S71.1 Open wound of thigh	0.006	0.994	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.006	0.994	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.006	0.994	0.000
S71.0 Open wound of hip	0.006	0.994	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.006	0.994	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.006	0.994	0.000
S72.30 Fracture of shaft of femur (closed)	0.006	0.994	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.006	0.994	0.000
T46.7 Peripheral vasodilators	0.006	0.994	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.006	0.994	0.000
M14.6 Neuropathic arthropathy	0.006	0.994	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.006	0.994	0.000
T45.8 Other primarily systemic and haematological agents	0.006	0.994	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.006	0.994	0.000
T45.6 Fibrinolysis-affecting drugs	0.006	0.994	0.000
T45.4 Iron and its compounds	0.006	0.994	0.000
T45.3 Enzymes, not elsewhere classified	0.006	0.994	0.000
T45.2 Vitamins, not elsewhere classified	0.006	0.994	0.000
S72.40 Fracture of lower end of femur (closed)	0.006	0.994	0.000
S78 Traumatic amputation of hip and thigh	0.006	0.994	0.000
S77 Crushing injury of hip and thigh	0.006	0.994	0.000
S75 Injury of blood vessels at hip and thigh level	0.006	0.994	0.000
S74 Injury of nerves at hip and thigh level	0.006	0.994	0.000
S72.7 Multiple fractures of femur	0.006	0.994	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.006	0.994	0.000
S70 Superficial injury of hip and thigh	0.006	0.994	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.006	0.994	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.006	0.994	0.000
T46.1 Calcium-channel blockers	0.006	0.994	0.000
E10.3 With ophthalmic complications	0.006	0.994	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.005	0.994	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.005	0.994	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.005	0.994	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.005	0.994	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.005	0.994	0.000
T44.0 Anticholinesterase agents	0.005	0.994	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.006	0.994	0.000
S01.3 Open wound of ear	0.006	0.994	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.005	0.994	0.000
S72.9 Fracture of femur, part unspecified	0.005	0.994	0.000
S72.21 Subtrochanteric fracture (open)	0.005	0.994	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.005	0.994	0.000
M08 Juvenile arthritis	0.005	0.994	0.000
M14.2 Diabetic arthropathy	0.005	0.994	0.000
M11 Other crystal arthropathies	0.005	0.994	0.001
T20-T25 Burns and corrosions of external body surface, specified by site	0.006	0.994	0.000
N05.9 Unspecified	0.006	0.994	0.000
M12 Other specific arthropathies	0.005	0.994	0.000
N03.8 Other	0.005	0.994	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.005	0.994	0.000
N03.6 Dense deposit disease	0.005	0.994	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.994	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.994	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.994	0.000
N03.2 Diffuse membranous glomerulonephritis	0.005	0.994	0.000
N03.1 Focal and segmental glomerular lesions	0.005	0.994	0.000
N03.0 Minor glomerular abnormality	0.005	0.994	0.000
T50.8 Diagnostic agents	0.005	0.994	0.000
T50.7 Analeptics and opioid receptor antagonists	0.005	0.994	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.005	0.994	0.000
T50.5 Appetite depressants	0.005	0.994	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.005	0.994	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.005	0.994	0.000
T50.1 Loop [high-ceiling] diuretics	0.005	0.994	0.000
T50.0 Mineralocorticoids and their antagonists	0.005	0.994	0.000
M05 Seropositive rheumatoid arthritis	0.005	0.995	0.000
S72.11 Pertrochanteric fracture (open)	0.005	0.995	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
T50.4 Drugs affecting uric acid metabolism	0.005	0.995	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.005	0.995	0.000
S71.7 Multiple open wounds of of hip and thigh	0.005	0.995	0.000
S73.1 Sprain and strain of hip	0.005	0.995	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.005	0.995	0.000
F60.9 Personality disorder, unspecified	0.005	0.995	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.005	0.995	0.000
T36 Poisoning by systemic antibiotics	0.005	0.995	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
S72.8 Fractures of other parts of femur	0.005	0.995	0.000
N05 Unspecified nephritic syndrome	0.005	0.995	0.000
N00-N08 Glomerular diseases	0.005	0.995	0.000
T20 Burn and corrosion of head and neck	0.005	0.995	0.000
S63.0 Dislocation of wrist	0.005	0.995	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.005	0.995	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
S72.31 Fracture of shaft of femur (open)	0.005	0.995	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.005	0.995	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.005	0.995	0.000
M14.4 Arthropathy in amyloidosis	0.005	0.995	0.000
M14.3 Lipoid dermatoarthritis	0.005	0.995	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.005	0.995	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.005	0.995	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.005	0.995	0.000
O14.9 Preeclampsia, unspecified	0.005	0.995	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.005	0.995	0.000
T40.6 Other and unspecified narcotics	0.005	0.995	0.000
T42.1 Iminostilbenes	0.005	0.995	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.005	0.995	0.000
T49.9 Topical agent, unspecified	0.005	0.995	0.000
T49.8 Other topical agents	0.005	0.995	0.000
T49.7 Dental drugs, topically applied	0.005	0.995	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
T49.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
T49.3 Emollients, demulcents and protectants	0.005	0.995	0.000
T49.2 Local astringents and local detergents	0.005	0.995	0.000
T49.1 Antipruritics	0.005	0.995	0.000
T09 Other injuries of spine and trunk, level unspecified	0.005	0.995	0.000
S70.8 Other superficial injuries of hip and thigh	0.005	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.6 Antidiarrhoeal drugs	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.4 Other laxatives	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
T47.2 Stimulant laxatives	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.005	0.995	0.000
S63.6 Sprain and strain of finger(s)	0.005	0.995	0.000
S76.1 Injury of quadriceps muscle and tendon	0.005	0.995	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.005	0.995	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.005	0.995	0.000
S76.0 Injury of muscle and tendon of hip	0.005	0.995	0.000
F60 Specific personality disorders	0.005	0.995	0.000
S72.41 Fracture of lower end of femur (open)	0.005	0.995	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.995	0.005
T37.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.995	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.005	0.995	0.000
S70.0 Contusion of hip	0.005	0.995	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.005	0.995	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.005	0.995	0.000
N72 Inflammatory disease of cervix uteri	0.000	0.995	0.005
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
T37.5 Antiviral drugs	0.005	0.995	0.000
T37.4 Anthelminthics	0.005	0.995	0.000
T37.3 Other antiprotozoal drugs	0.005	0.995	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
T37.1 Antimycobacterial drugs	0.005	0.995	0.000
T37.0 Sulphonamides	0.005	0.995	0.000
T38.9 Other and unspecified hormone antagonists	0.005	0.995	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.995	0.000
T38.7 Androgens and anabolic congeners	0.005	0.995	0.000
T38.5 Other oestrogens and progestogens	0.005	0.995	0.000
T38.4 Oral contraceptives	0.005	0.995	0.000
T38.2 Antithyroid drugs	0.005	0.995	0.000
T38.0 Glucocorticoids and synthetic analogues	0.005	0.995	0.000
M06 Other rheumatoid arthritis	0.005	0.995	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.005	0.995	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.005	0.995	0.000
S79 Other and unspecified injuries of hip and thigh	0.005	0.995	0.000
T41.5 Therapeutic gases	0.004	0.995	0.000
T41.4 Anaesthetic, unspecified	0.004	0.995	0.000
T41.3 Local anaesthetics	0.004	0.995	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.995	0.000
T41.1 Intravenous anaesthetics	0.004	0.995	0.000
T41.0 Inhaled anaesthetics	0.004	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.995	0.000
T48.5 Anti-common-cold drugs	0.004	0.995	0.000
T48.4 Expectorants	0.004	0.995	0.000
T48.3 Antitussives	0.004	0.995	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.995	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.995	0.000
T48.0 Oxytocic drugs	0.004	0.995	0.000
T11 Other injuries of upper limb, level unspecified	0.005	0.995	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.005	0.995	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.005	0.995	0.000
S62.50 Fracture of thumb (closed)	0.005	0.995	0.000
F60.3 Emotionally unstable personality disorder	0.005	0.995	0.000
R68.8 Other specified general symptoms and signs	0.000	0.995	0.005
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.004	0.995	0.000
T40.8 Lysergide [LSD]	0.004	0.995	0.000
T40.7 Cannabis (derivatives)	0.004	0.995	0.000
T40.5 Cocaine	0.004	0.995	0.000
T40.3 Methadone	0.004	0.995	0.000
T40.1 Heroin	0.004	0.995	0.000
T40.0 Opium	0.004	0.995	0.000
F60.8 Other specific personality disorders	0.005	0.995	0.000
M11.9 Crystal arthropathy, unspecified	0.004	0.995	0.001
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.005	0.995	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.004	0.995	0.000
T20.3 Burn of third degree of head and neck	0.004	0.995	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.004	0.995	0.000
S74.8 Injury of other nerves at hip and thigh level	0.004	0.995	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.004	0.995	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.004	0.995	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.004	0.995	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.004	0.995	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.004	0.995	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.004	0.995	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.004	0.995	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.004	0.995	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.004	0.995	0.000
S75.0 Injury of femoral artery	0.004	0.995	0.000
S77.2 Crushing injury of hip with thigh	0.004	0.995	0.000
S77.1 Crushing injury of thigh	0.004	0.995	0.000
S77.0 Crushing injury of hip	0.004	0.995	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.004	0.995	0.000
S78.1 Traumatic amputation at level between hip and knee	0.004	0.995	0.000
S78.0 Traumatic amputation at hip joint	0.004	0.995	0.000
T38.1 Thyroid hormones and substitutes	0.004	0.995	0.000
T40.2 Other opioids	0.005	0.995	0.000
S72.71 Multiple fractures of femur (open)	0.004	0.995	0.000
S72.70 Multiple fractures of femur (closed)	0.004	0.995	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.004	0.995	0.000
T09.9 Unspecified injury of trunk, level unspecified	0.004	0.996	0.000
T20.1 Burn of first degree of head and neck	0.004	0.996	0.000
T33-T35 Frostbite	0.004	0.996	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.004	0.996	0.000
S10-S19 Injuries to the neck	0.004	0.996	0.000
S01.1 Open wound of eyelid and periocular area	0.004	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.004	0.996	0.000
T39.2 Pyrazolone derivatives	0.004	0.996	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.004	0.996	0.000
T23 Burn and corrosion of wrist and hand	0.004	0.996	0.000
T20.0 Burn of unspecified degree of head and neck	0.004	0.996	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
S50-S59 Injuries to the elbow and forearm	0.004	0.996	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.004	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.996	0.000
T42.3 Barbiturates	0.004	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
N02 Recurrent and persistent haematuria	0.004	0.996	0.000
S56 Injury of muscle and tendon at forearm level	0.004	0.996	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.004	0.996	0.000
S72.91 Fracture of femur, part unspecified (open)	0.004	0.996	0.000
M08.9 Juvenile arthritis, unspecified	0.004	0.996	0.000
M08.8 Other juvenile arthritis	0.004	0.996	0.000
M08.4 Pauciarticular juvenile arthritis	0.004	0.996	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.004	0.996	0.000
M08.2 Juvenile arthritis with systemic onset	0.004	0.996	0.000
M08.1 Juvenile ankylosing spondylitis	0.004	0.996	0.000
M08.0 Juvenile rheumatoid arthritis	0.004	0.996	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.004	0.996	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.004	0.996	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.004	0.996	0.000
M09.0 Juvenile arthritis in psoriasis	0.004	0.996	0.000
T09.0 Superficial injury of trunk, level unspecified	0.004	0.996	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.004	0.996	0.000
N05.2 Diffuse membranous glomerulonephritis	0.004	0.996	0.000
M11.8 Other specified crystal arthropathies	0.004	0.996	0.001
M11.1 Familial chondrocalcinosis	0.004	0.996	0.001
M11.0 Hydroxyapatite deposition disease	0.004	0.996	0.001
M12.8 Other specific arthropathies, not elsewhere classified	0.004	0.996	0.000
M12.5 Traumatic arthropathy	0.004	0.996	0.000
M12.4 Intermittent hydrarthrosis	0.004	0.996	0.000
M12.3 Palindromic rheumatism	0.004	0.996	0.000
M12.1 Kaschin-Beck disease	0.004	0.996	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.004	0.996	0.000
S62.5 Fracture of thumb	0.004	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.004	0.996	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.004	0.996	0.000
N04 Nephrotic syndrome	0.004	0.996	0.000
M13 Other arthritis	0.004	0.996	0.000
M05.8 Other seropositive rheumatoid arthritis	0.004	0.996	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.004	0.996	0.000
M05.2 Rheumatoid vasculitis	0.004	0.996	0.000
M05.1 Rheumatoid lung disease	0.004	0.996	0.000
M05.0 Felty's syndrome	0.004	0.996	0.000
M12.2 Villonodular synovitis (pigmented)	0.004	0.996	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.996	0.004
M11.2 Other chondrocalcinosis	0.002	0.996	0.002
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.004	0.996	0.000
S60-S69 Injuries to the wrist and hand	0.004	0.996	0.000
S63.1 Dislocation finger	0.004	0.996	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.004	0.996	0.000
S63.2 Multiple dislocations of fingers	0.004	0.996	0.000
Z00.4 General psychiatric examination, not elsewhere classified	0.004	0.996	0.000
S00-S09 Injuries to the head	0.004	0.996	0.000
N05.1 Focal and segmental glomerular lesions	0.004	0.996	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.004	0.996	0.000
T36.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
T36.8 Other systemic antibiotics	0.004	0.996	0.000
T36.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
T36.6 Rifamycins	0.004	0.996	0.000
T36.5 Aminoglycosides	0.004	0.996	0.000
T36.4 Tetracyclines	0.004	0.996	0.000
T36.3 Macrolides	0.004	0.996	0.000
T36.2 Chloramphenicol group	0.004	0.996	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.004	0.996	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.004	0.996	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.004	0.996	0.000
T11.1 Open wound of upper limb, level unspecified	0.004	0.996	0.000
Z00.8 Other general examinations	0.004	0.996	0.000
M07 Psoriatic and enteropathic arthropathies	0.004	0.996	0.000
S40-S49 Injuries to the shoulder and upper arm	0.004	0.996	0.000
T09.3 Injury of spinal cord, level unspecified	0.004	0.996	0.000
S72.81 Fractures of other parts of femur (open)	0.004	0.996	0.000
N05.6 Dense deposit disease	0.004	0.996	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.004	0.996	0.000
N05.0 Minor glomerular abnormality	0.004	0.996	0.000
T20.7 Corrosion of third degree of head and neck	0.004	0.996	0.000
T20.6 Corrosion of second degree of head and neck	0.004	0.996	0.000
T20.5 Corrosion of first degree of head and neck	0.004	0.996	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.004	0.996	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.004	0.996	0.000
N06 Isolated proteinuria with specified morphological lesion	0.004	0.996	0.000
N01 Rapidly progressive nephritic syndrome	0.004	0.996	0.000
N00 Acute nephritic syndrome	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations