TreeWAS – Variant ID: rs2206250

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90 Intestinal malabsorption	0.000	0.684	0.315
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.740	0.260
K90.3 Pancreatic steatorrhoea	0.000	0.774	0.226
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.774	0.226
K90.1 Tropical sprue	0.000	0.774	0.226
K90.8 Other intestinal malabsorption	0.000	0.782	0.218
E10 Insulin-dependent diabetes mellitus	0.000	0.854	0.146
E10.9 Without complications	0.000	0.854	0.146
E10.5 With peripheral circulatory complications	0.000	0.867	0.133
E10.4 With neurological complications	0.000	0.867	0.133
E10.6 With other specified complications	0.000	0.870	0.130
E83 Disorders of mineral metabolism	0.000	0.871	0.129
E10.8 With unspecified complications	0.000	0.876	0.124
E10.2 With renal complications	0.000	0.890	0.110
E10.1 With ketoacidosis	0.000	0.893	0.107
E10.7 With multiple complications	0.000	0.895	0.105
E10-E14 Diabetes mellitus	0.000	0.898	0.102
K90.9 Intestinal malabsorption, unspecified	0.000	0.901	0.098
E10.0 With coma	0.000	0.905	0.095
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.908	0.092
E83.8 Other disorders of mineral metabolism	0.000	0.908	0.092
E83.2 Disorders of zinc metabolism	0.000	0.908	0.092
E83.0 Disorders of copper metabolism	0.000	0.908	0.092
E10.3 With ophthalmic complications	0.000	0.912	0.088
E13 Other specified diabetes mellitus	0.000	0.913	0.087
E13.9 Without complications	0.000	0.923	0.077
E14 Unspecified diabetes mellitus	0.000	0.924	0.076
E12 Malnutrition-related diabetes mellitus	0.000	0.926	0.073
E14.3 With ophthalmic complications	0.000	0.927	0.073
E70-E90 Metabolic disorders	0.000	0.927	0.073
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.928	0.072
E13.8 With unspecified complications	0.000	0.937	0.062
E13.7 With multiple complications	0.000	0.937	0.062
E13.6 With other specified complications	0.000	0.937	0.062
E13.5 With peripheral circulatory complications	0.000	0.937	0.062
E13.4 With neurological complications	0.000	0.937	0.062
E13.2 With renal complications	0.000	0.937	0.062
E13.1 With ketoacidosis	0.000	0.937	0.062
E13.0 With coma	0.000	0.937	0.062
E88 Other metabolic disorders	0.000	0.938	0.062
E13.3 With ophthalmic complications	0.000	0.939	0.061
E40-E46 Malnutrition	0.000	0.940	0.060
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.940	0.060
E85 Amyloidosis	0.000	0.941	0.059
E14.5 With peripheral circulatory complications	0.000	0.943	0.057
E83.3 Disorders of phosphorus metabolism	0.000	0.944	0.056
E14.7 With multiple complications	0.000	0.945	0.055
E14.6 With other specified complications	0.000	0.945	0.055
E14.2 Withrenal complications	0.000	0.945	0.055
E14.0 With coma	0.000	0.945	0.055
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.945	0.055
E83.4 Disorders of magnesium metabolism	0.000	0.946	0.054
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.946	0.054
E12.9 Without complications	0.000	0.947	0.053
E12.8 With unspecified complications	0.000	0.947	0.053
E12.7 With multiple complications	0.000	0.947	0.053
E12.6 With other specified complications	0.000	0.947	0.053
E12.5 With peripheral circulatory complications	0.000	0.947	0.053
E12.4 With neurological complications	0.000	0.947	0.053
E12.3 With ophthalmic complications	0.000	0.947	0.053
E12.2 With renal complications	0.000	0.947	0.053
E12.1 With ketoacidosis	0.000	0.947	0.053
E12.0 With coma	0.000	0.947	0.053
E14.4 With neurological complications	0.000	0.947	0.053
E84 Cystic fibrosis	0.000	0.947	0.052
E77 Disorders of glycoprotein metabolism	0.000	0.947	0.052
E76 Disorders of glycosaminoglycan metabolism	0.000	0.947	0.052
E72 Other disorders of amino-acid metabolism	0.000	0.947	0.052
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.947	0.052
E70 Disorders of aromatic amino-acid metabolism	0.000	0.947	0.052
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.947	0.052
E46 Unspecified protein-energy malnutrition	0.000	0.948	0.052
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.948	0.052
E16 Other disorders of pancreatic internal secretion	0.000	0.949	0.051
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.949	0.051
E85.9 Amyloidosis, unspecified	0.000	0.950	0.050
E65-E68 Obesity and other hyperalimentation	0.000	0.952	0.048
E16.2 Hypoglycaemia, unspecified	0.000	0.952	0.048
E79 Disorders of purine and pyrimidine metabolism	0.000	0.952	0.047
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.953	0.047
E88.8 Other specified metabolic disorders	0.000	0.953	0.047
E88.2 Lipomatosis, not elsewhere classified	0.000	0.953	0.047
E14.1 With ketoacidosis	0.000	0.953	0.046
E14.8 With unspecified complications	0.000	0.955	0.045
E85.4 Organ-limited amyloidosis	0.000	0.955	0.045
E88.3 Tumour lysis syndrome	0.000	0.955	0.045
E89.2 Postprocedural hypoparathyroidism	0.000	0.956	0.044
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.957	0.043
E45 Retarded development following protein-energy malnutrition	0.000	0.957	0.043
E43 Unspecified severe protein-energy malnutrition	0.000	0.957	0.043
E42 Marasmic kwashiorkor	0.000	0.957	0.043
E41 Nutritional marasmus	0.000	0.957	0.043
E40 Kwashiorkor	0.000	0.957	0.043
E15 Nondiabetic hypoglycaemic coma	0.000	0.957	0.043
E85.8 Other amyloidosis	0.000	0.957	0.043
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.957	0.043
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.957	0.043
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.957	0.043
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.958	0.042
E11 Non-insulin-dependent diabetes mellitus	0.000	0.958	0.042
E74 Other disorders of carbohydrate metabolism	0.000	0.958	0.041
E88.9 Metabolic disorder, unspecified	0.000	0.958	0.041
E65 Localised adiposity	0.000	0.958	0.042
E89.0 Postprocedural hypothyroidism	0.000	0.959	0.041
E89.4 Postprocedural ovarian failure	0.000	0.959	0.041
E80.4 Gilbert's syndrome	0.000	0.960	0.040
E85.3 Secondary systemic amyloidosis	0.000	0.960	0.040
E75.5 Other lipid storage disorders	0.000	0.960	0.040
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.961	0.039
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.961	0.039
E89.5 Postprocedural testicular hypofunction	0.000	0.961	0.039
E89.1 Postprocedural hypoinsulinaemia	0.000	0.961	0.039
E73 Lactose intolerance	0.000	0.961	0.038
E75.6 Lipid storage disorder, unspecified	0.000	0.961	0.039
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.961	0.039
E75.3 Sphingolipidosis, unspecified	0.000	0.961	0.039
E75.2 Other sphingolipidosis	0.000	0.961	0.039
E75.1 Other gangliosidosis	0.000	0.961	0.039
E75.0 GM2 gangliosidosis	0.000	0.961	0.039
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.962	0.038
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.962	0.038
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.962	0.038
E70.3 Albinism	0.000	0.962	0.038
E70.2 Disorders of tyrosine metabolism	0.000	0.962	0.038
E70.1 Other hyperphenylalaninaemias	0.000	0.962	0.038
E70.0 Classical phenylketonuria	0.000	0.962	0.038
E71.3 Disorders of fatty-acid metabolism	0.000	0.962	0.038
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.962	0.038
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.962	0.038
E71.0 Maple-syrup-urine disease	0.000	0.962	0.038
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.962	0.038
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.962	0.038
E72.5 Disorders of glycine metabolism	0.000	0.962	0.038
E72.4 Disorders of ornithine metabolism	0.000	0.962	0.038
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.962	0.038
E72.2 Disorders of urea cycle metabolism	0.000	0.962	0.038
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.962	0.038
E72.0 Disorders of amino-acid transport	0.000	0.962	0.038
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.962	0.038
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.962	0.038
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.962	0.038
E76.2 Other mucopolysaccharidoses	0.000	0.962	0.038
E76.1 Mucopolysaccharidosis, type II	0.000	0.962	0.038
E76.0 Mucopolysaccharidosis, type I	0.000	0.962	0.038
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.962	0.038
E77.8 Other disorders of glycoprotein metabolism	0.000	0.962	0.038
E77.1 Defects in glycoprotein degradation	0.000	0.962	0.038
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.962	0.038
E84.9 Cystic fibrosis, unspecified	0.000	0.962	0.038
E84.8 Cystic fibrosis with other manifestations	0.000	0.962	0.038
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.962	0.038
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.962	0.038
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.962	0.038
E80.5 Crigler-Najjar syndrome	0.000	0.962	0.038
E80.3 Defects of catalase and peroxydase	0.000	0.962	0.038
E80.1 Porphyria cutanea tarda	0.000	0.962	0.038
E80.0 Hereditary erythropoietic porphyria	0.000	0.962	0.038
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.963	0.037
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.963	0.037
E16.4 Abnormal secretion of gastrin	0.000	0.963	0.037
E16.3 Increased secretion of glucagon	0.000	0.963	0.037
E80.2 Other porphyria	0.000	0.964	0.036
E80.6 Other disorders of bilirubin metabolism	0.000	0.964	0.036
E11.5 With peripheral circulatory complications	0.000	0.965	0.035
E67 Other hyperalimentation	0.000	0.965	0.035
E68 Sequelae of hyperalimentation	0.000	0.965	0.035
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.966	0.034
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.966	0.034
E79.1 Lesch-Nyhan syndrome	0.000	0.966	0.034
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.967	0.033
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.967	0.033
E11.0 With coma	0.000	0.968	0.032
E11.8 With unspecified complications	0.000	0.969	0.031
E44.1 Mild protein-energy malnutrition	0.000	0.969	0.031
E44.0 Moderate protein-energy malnutrition	0.000	0.969	0.031
E11.1 With ketoacidosis	0.000	0.969	0.031
E11.2 With renal complications	0.000	0.969	0.030
E11.7 With multiple complications	0.000	0.970	0.030
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.970	0.030
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.970	0.030
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.970	0.030
E74.2 Disorders of galactose metabolism	0.000	0.970	0.030
E74.1 Disorders of fructose metabolism	0.000	0.970	0.030
E83.5 Disorders of calcium metabolism	0.000	0.970	0.030
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.970	0.029
E00-E07 Disorders of thyroid gland	0.000	0.971	0.029
E16.1 Other hypoglycaemia	0.000	0.972	0.028
E73.8 Other lactose intolerance	0.000	0.972	0.028
E73.1 Secondary lactase deficiency	0.000	0.972	0.028
E73.0 Congenital lactase deficiency	0.000	0.972	0.028
E11.6 With other specified complications	0.000	0.972	0.028
E74.0 Glycogen storage disease	0.000	0.972	0.027
E78.4 Other hyperlipidaemia	0.000	0.973	0.027
E11.4 With neurological complications	0.000	0.973	0.027
E67.8 Other specified hyperalimentation	0.000	0.975	0.025
E67.3 Hypervitaminosis D	0.000	0.975	0.025
E67.2 Megavitamin-B6 syndrome	0.000	0.975	0.025
E67.1 Hypercarotenaemia	0.000	0.975	0.025
E67.0 Hypervitaminosis A	0.000	0.975	0.025
E50-E64 Other nutritional deficiencies	0.000	0.975	0.025
E78.6 Lipoprotein deficiency	0.000	0.975	0.025
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.975	0.025
E89.3 Postprocedural hypopituitarism	0.000	0.976	0.024
E78.3 Hyperchylomicronaemia	0.000	0.976	0.024
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.977	0.023
E87.3 Alkalosis	0.000	0.977	0.023
E07 Other disorders of thyroid	0.000	0.977	0.022
E78.1 Pure hyperglyceridaemia	0.000	0.978	0.022
E14.9 Without complications	0.000	0.978	0.022
E78.2 Mixed hyperlipidaemia	0.000	0.978	0.022
E04 Other non-toxic goitre	0.000	0.979	0.021
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.979	0.021
E00 Congenital iodine-deficiency syndrome	0.000	0.979	0.021
E20-E35 Disorders of other endocrine glands	0.000	0.979	0.021
E87.0 Hyperosmolality and hypernatraemia	0.000	0.979	0.021
K90-K93 Other diseases of the digestive system	0.000	0.980	0.020
E11.3 With ophthalmic complications	0.000	0.980	0.020
E06 Thyroiditis	0.000	0.980	0.020
E03 Other hypothyroidism	0.000	0.981	0.019
E07.9 Disorder of thyroid, unspecified	0.000	0.981	0.019
E04.9 Non-toxic goitre, unspecified	0.000	0.981	0.019
E87.7 Fluid overload	0.000	0.982	0.018
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.982	0.018
E63 Other nutritional deficiencies	0.000	0.982	0.018
E56 Other vitamin deficiencies	0.000	0.982	0.018
E50 Vitamin A deficiency	0.000	0.982	0.018
E60 Dietary zinc deficiency	0.000	0.982	0.018
E59 Dietary selenium deficiency	0.000	0.982	0.018
E54 Ascorbic acid deficiency	0.000	0.982	0.018
E52 Niacin deficiency [pellagra]	0.000	0.982	0.018
E87.2 Acidosis	0.000	0.982	0.018
E58 Dietary calcium deficiency	0.000	0.982	0.018
E87.4 Mixed disorder of acid-base balance	0.000	0.982	0.018
E03.8 Other specified hypothyroidism	0.000	0.982	0.018
E53 Deficiency of other B group vitamins	0.000	0.983	0.017
E51 Thiamine deficiency	0.000	0.983	0.017
E07.1 Dyshormogenetic goitre	0.000	0.984	0.016
E07.0 Hypersecretion of calcitonin	0.000	0.984	0.016
E04.0 Non-toxic diffuse goitre	0.000	0.984	0.016
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.984	0.016
E28 Ovarian dysfunction	0.000	0.984	0.016
E66 Obesity	0.000	0.984	0.016
E26 Hyperaldosteronism	0.000	0.984	0.016
R31 Unspecified haematuria	0.016	0.984	0.000
E04.8 Other specified non-toxic goitre	0.000	0.984	0.015
E20 Hypoparathyroidism	0.000	0.984	0.015
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.985	0.015
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.985	0.015
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.985	0.015
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.985	0.015
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.985	0.015
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.985	0.015
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.985	0.015
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.985	0.015
E23 Hypofunction and other disorders of pituitary gland	0.000	0.985	0.015
E29 Testicular dysfunction	0.000	0.985	0.015
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.985	0.015
E32 Diseases of thymus	0.000	0.985	0.015
E31 Polyglandular dysfunction	0.000	0.985	0.015
E30 Disorders of puberty, not elsewhere classified	0.000	0.985	0.015
E25 Adrenogenital disorders	0.000	0.985	0.015
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.985	0.015
E28.2 Polycystic ovarian syndrome	0.000	0.985	0.015
E06.3 Autoimmune thyroiditis	0.000	0.985	0.015
E07.8 Other specified disorders of thyroid	0.000	0.985	0.014
E06.5 Other chronic thyroiditis	0.000	0.986	0.014
E06.4 Drug-induced thyroiditis	0.000	0.986	0.014
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.986	0.014
E06.1 Subacute thyroiditis	0.000	0.986	0.014
E06.0 Acute thyroiditis	0.000	0.986	0.014
E73.9 Lactose intolerance, unspecified	0.001	0.986	0.014
E23.2 Diabetes insipidus	0.000	0.986	0.014
E04.2 Non-toxic multinodular goitre	0.000	0.986	0.014
E78.8 Other disorders of lipoprotein metabolism	0.000	0.986	0.014
E87.5 Hyperkalaemia	0.000	0.986	0.014
E55 Vitamin D deficiency	0.000	0.986	0.014
E03.5 Myxoedema coma	0.000	0.986	0.014
E03.4 Atrophy of thyroid (acquired)	0.000	0.986	0.014
E03.3 Postinfectious hypothyroidism	0.000	0.986	0.014
E03.1 Congenital hypothyroidism without goitre	0.000	0.986	0.014
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.986	0.014
E34 Other endocrine disorders	0.000	0.986	0.014
E24 Cushing's syndrome	0.000	0.986	0.014
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.986	0.014
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.986	0.014
C71.2 Temporal lobe	0.013	0.987	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.987	0.013
E50.8 Other manifestations of vitamin A deficiency	0.000	0.987	0.013
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.987	0.013
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.987	0.013
E50.5 Vitamin A deficiency with night blindness	0.000	0.987	0.013
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.987	0.013
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.987	0.013
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.987	0.013
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.987	0.013
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.987	0.013
E56.9 Vitamin deficiency, unspecified	0.000	0.987	0.013
E56.8 Deficiency of other vitamins	0.000	0.987	0.013
E56.1 Deficiency of vitamin K	0.000	0.987	0.013
E56.0 Deficiency of vitamin E	0.000	0.987	0.013
E63.9 Nutritional deficiency, unspecified	0.000	0.987	0.013
E63.8 Other specified nutritional deficiencies	0.000	0.987	0.013
E63.1 Imbalance of constituents of food intake	0.000	0.987	0.013
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.987	0.013
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.987	0.013
E64.8 Sequelae of other nutritional deficiencies	0.000	0.987	0.013
E64.3 Sequelae of rickets	0.000	0.987	0.013
E64.2 Sequelae of vitamin C deficiency	0.000	0.987	0.013
E64.1 Sequelae of vitamin A deficiency	0.000	0.987	0.013
E64.0 Sequelae of protein-energy malnutrition	0.000	0.987	0.013
C71 Malignant neoplasm of brain	0.013	0.987	0.000
E27 Other disorders of adrenal gland	0.000	0.987	0.013
E53.1 Pyridoxine deficiency	0.000	0.987	0.012
E53.0 Riboflavin deficiency	0.000	0.987	0.012
E06.9 Thyroiditis, unspecified	0.000	0.987	0.013
C71.9 Brain, unspecified	0.013	0.987	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.987	0.012
E27.1 Primary adrenocortical insufficiency	0.000	0.988	0.012
E51.9 Thiamine deficiency, unspecified	0.000	0.988	0.012
E51.8 Other manifestations of thiamine deficiency	0.000	0.988	0.012
E51.1 Beriberi	0.000	0.988	0.012
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.988	0.012
E26.0 Primary hyperaldosteronism	0.000	0.988	0.012
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.988	0.012
E28.9 Ovarian dysfunction, unspecified	0.000	0.988	0.012
E28.8 Other ovarian dysfunction	0.000	0.988	0.012
E28.1 Androgen excess	0.000	0.988	0.012
E28.0 Oestrogen excess	0.000	0.988	0.012
E20.9 Hypoparathyroidism, unspecified	0.000	0.988	0.012
E53.8 Deficiency of other specified B group vitamins	0.000	0.988	0.012
E24.2 Drug-induced Cushing's syndrome	0.000	0.988	0.012
E66.1 Drug-induced obesity	0.000	0.988	0.012
E26.9 Hyperaldosteronism, unspecified	0.000	0.988	0.011
E26.8 Other hyperaldosteronism	0.000	0.988	0.011
E26.1 Secondary hyperaldosteronism	0.000	0.988	0.011
E20.8 Other hypoparathyroidism	0.000	0.989	0.011
E20.1 Pseudohypoparathyroidism	0.000	0.989	0.011
E20.0 Idiopathic hypoparathyroidism	0.000	0.989	0.011
E66.0 Obesity due to excess calories	0.000	0.989	0.011
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.989	0.011
E23.1 Drug-induced hypopituitarism	0.000	0.989	0.011
E29.9 Testicular dysfunction, unspecified	0.000	0.989	0.011
E29.8 Other testicular dysfunction	0.000	0.989	0.011
E29.0 Testicular hyperfunction	0.000	0.989	0.011
E25.9 Adrenogenital disorder, unspecified	0.000	0.989	0.011
E25.8 Other adrenogenital disorders	0.000	0.989	0.011
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.989	0.011
E30.9 Disorder of puberty, unspecified	0.000	0.989	0.011
E30.8 Other disorders of puberty	0.000	0.989	0.011
E30.1 Precocious puberty	0.000	0.989	0.011
E30.0 Delayed puberty	0.000	0.989	0.011
E31.9 Polyglandular dysfunction, unspecified	0.000	0.989	0.011
E31.8 Other polyglandular dysfunction	0.000	0.989	0.011
E31.1 Polyglandular hyperfunction	0.000	0.989	0.011
E31.0 Autoimmune polyglandular failure	0.000	0.989	0.011
E32.9 Disease of thymus, unspecified	0.000	0.989	0.011
E32.8 Other diseases of thymus	0.000	0.989	0.011
E32.1 Abscess of thymus	0.000	0.989	0.011
E32.0 Persistent hyperplasia of thymus	0.000	0.989	0.011
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.989	0.011
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.989	0.011
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.989	0.011
E29.1 Testicular hypofunction	0.000	0.989	0.011
E51.2 Wernicke's encephalopathy	0.000	0.989	0.011
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.989	0.011
K93.1 Megacolon in Chagas' disease	0.000	0.989	0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.989	0.011
E23.7 Disorder of pituitary gland, unspecified	0.000	0.989	0.011
C71.3 Parietal lobe	0.011	0.989	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.989	0.011
C71.1 Frontal lobe	0.011	0.989	0.000
E55.0 Rickets, active	0.000	0.990	0.010
G44.2 Tension-type headache	0.010	0.990	0.000
M41.9 Scoliosis, unspecified	0.010	0.990	0.000
E24.8 Other Cushing's syndrome	0.000	0.990	0.010
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.990	0.010
E24.3 Ectopic ACTH syndrome	0.000	0.990	0.010
E24.1 Nelson's syndrome	0.000	0.990	0.010
E34.5 Androgen resistance syndrome	0.000	0.990	0.010
E34.4 Constitutional tall stature	0.000	0.990	0.010
E34.3 Short stature, not elsewhere classified	0.000	0.990	0.010
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.990	0.010
E34.1 Other hypersecretion of intestinal hormones	0.000	0.990	0.010
E34.9 Endocrine disorder, unspecified	0.000	0.990	0.010
E61 Deficiency of other nutrient elements	0.001	0.990	0.009
M41.96 Scoliosis, unspecified (Lumbar region)	0.010	0.990	0.000
C71.7 Brain stem	0.010	0.990	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.990	0.010
E34.8 Other specified endocrine disorders	0.000	0.990	0.010
E23.6 Other disorders of pituitary gland	0.000	0.990	0.010
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.990	0.010
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.010	0.990	0.000
C71.6 Cerebellum	0.009	0.990	0.000
C71.5 Cerebral ventricle	0.009	0.990	0.000
C71.0 Cerebrum, except lobes and ventricles	0.009	0.990	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.009	0.991	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.991	0.009
E27.0 Other adrenocortical overactivity	0.000	0.991	0.009
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.991	0.009
M41.99 Scoliosis, unspecified (Site unspecified)	0.009	0.991	0.000
E05.8 Other thyrotoxicosis	0.000	0.991	0.009
C71.8 Overlapping lesion of brain	0.009	0.991	0.000
E34.0 Carcinoid syndrome	0.000	0.991	0.009
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.991	0.009
E05.5 Thyroid crisis or storm	0.000	0.991	0.009
E05.4 Thyrotoxicosis factitia	0.000	0.991	0.009
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.991	0.009
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.991	0.009
E24.0 Pituitary-dependent Cushing's disease	0.000	0.991	0.009
C71.4 Occipital lobe	0.008	0.992	0.000
E28.3 Primary ovarian failure	0.000	0.992	0.007
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.008	0.992	0.000
E86 Volume depletion	0.000	0.992	0.008
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.007	0.992	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.007	0.992	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.007	0.992	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.007	0.992	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.992	0.008
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.007	0.992	0.000
E61.9 Deficiency of nutrient element, unspecified	0.001	0.993	0.007
E61.8 Deficiency of other specified nutrient elements	0.001	0.993	0.007
E61.7 Deficiency of multiple nutrient elements	0.001	0.993	0.007
E61.6 Vanadium deficiency	0.001	0.993	0.007
E61.5 Molybdenum deficiency	0.001	0.993	0.007
E61.4 Chromium deficiency	0.001	0.993	0.007
E61.3 Manganese deficiency	0.001	0.993	0.007
E61.0 Copper deficiency	0.001	0.993	0.007
E27.2 Addisonian crisis	0.000	0.993	0.007
E24.9 Cushing's syndrome, unspecified	0.000	0.993	0.007
E21.3 Hyperparathyroidism, unspecified	0.000	0.993	0.007
M79.10 Myalgia (Multiple sites)	0.007	0.993	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.993	0.007
E21.2 Other hyperparathyroidism	0.000	0.993	0.007
E22 Hyperfunction of pituitary gland	0.000	0.993	0.006
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.993	0.007
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.006	0.993	0.000
C69 Malignant neoplasm of eye and adnexa	0.007	0.993	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.993	0.006
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.993	0.006
G31.0 Circumscribed brain atrophy	0.000	0.994	0.006
E27.8 Other specified disorders of adrenal gland	0.000	0.994	0.006
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.994	0.006
E61.2 Magnesium deficiency	0.001	0.994	0.005
E23.0 Hypopituitarism	0.000	0.994	0.006
E55.9 Vitamin D deficiency, unspecified	0.000	0.994	0.006
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.994	0.006
C70 Malignant neoplasm of meninges	0.006	0.994	0.000
N04.9 Unspecified	0.000	0.994	0.006
E27.9 Disorder of adrenal gland, unspecified	0.000	0.994	0.005
C69.9 Eye, unspecified	0.006	0.994	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.005	0.995	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.005	0.995	0.000
C69.3 Choroid	0.005	0.995	0.000
G44 Other headache syndromes	0.005	0.995	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.995	0.005
E22.8 Other hyperfunction of pituitary gland	0.000	0.995	0.005
M41 Scoliosis	0.005	0.995	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.995	0.005
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.005	0.995	0.000
C69.8 Overlapping lesion of eye and adnexa	0.005	0.995	0.000
C69.5 Lachrymal gland and duct	0.005	0.995	0.000
C69.4 Ciliary body	0.005	0.995	0.000
C69.2 Retina	0.005	0.995	0.000
C69.1 Cornea	0.005	0.995	0.000
C70.0 Cerebral meninges	0.005	0.995	0.000
C69.6 Orbit	0.005	0.995	0.000
M79.19 Myalgia (Site unspecified)	0.005	0.995	0.000
C69.0 Conjunctiva	0.005	0.995	0.000
G44.8 Other specified headache syndromes	0.005	0.995	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.995	0.005
M79.1 Myalgia	0.005	0.995	0.000
C70.9 Meninges, unspecified	0.004	0.995	0.000
C70.1 Spinal meninges	0.004	0.995	0.000
E22.1 Hyperprolactinaemia	0.000	0.995	0.004
G54.9 Nerve root and plexus disorder, unspecified	0.004	0.996	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.996	0.004
C72.9 Central nervous system, unspecified	0.004	0.996	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.004	0.996	0.000
C72.5 Other and unspecified cranial nerves	0.004	0.996	0.000
C72.4 Acoustic nerve	0.004	0.996	0.000
C72.3 Optic nerve	0.004	0.996	0.000
C72.2 Olfactory nerve	0.004	0.996	0.000
C72.1 Cauda equina	0.004	0.996	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.996	0.004
E66.9 Obesity, unspecified	0.000	0.996	0.004
G31.2 Degeneration of nervous system due to alcohol	0.000	0.996	0.004
G44.1 Vascular headache, not elsewhere classified	0.004	0.996	0.000
C72.0 Spinal cord	0.004	0.996	0.000
M22.2 Patellofemoral disorders	0.004	0.996	0.000
M41.5 Other secondary scoliosis	0.004	0.996	0.000
M41.4 Neuromuscular scoliosis	0.004	0.996	0.000
M41.3 Thoracogenic scoliosis	0.004	0.996	0.000
M41.2 Other idiopathic scoliosis	0.004	0.996	0.000
M41.1 Juvenile idiopathic scoliosis	0.004	0.996	0.000
M41.0 Infantile idiopathic scoliosis	0.004	0.996	0.000
G44.3 Chronic posttraumatic headache	0.004	0.996	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.996	0.004
K22.8 Other specified diseases of oesophagus	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations