TreeWAS – Variant ID: rs2212361

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.087	0.913	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.085	0.915	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.083	0.917	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.083	0.917	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.082	0.918	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.078	0.922	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.074	0.926	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.071	0.928	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.054	0.946	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.015	0.985	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.014	0.986	0.000
H57.0 Anomalies of pupillary function	0.013	0.987	0.000
K65.9 Peritonitis, unspecified	0.013	0.987	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.012	0.988	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.988	0.012
H57 Other disorders of eye and adnexa	0.012	0.988	0.000
S82.40 Fracture of fibula alone (closed)	0.011	0.989	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.009	0.991	0.000
H57.1 Ocular pain	0.009	0.991	0.000
H57.8 Other specified disorders of eye and adnexa	0.008	0.992	0.000
M23.8 Other internal derangements of knee	0.008	0.992	0.000
E04.9 Non-toxic goitre, unspecified	0.008	0.992	0.000
E04.2 Non-toxic multinodular goitre	0.007	0.993	0.000
S50.0 Contusion of elbow	0.000	0.993	0.007
K65 Peritonitis	0.007	0.993	0.000
K65.8 Other peritonitis	0.007	0.993	0.000
S50.9 Superficial injury of forearm, unspecified	0.000	0.993	0.007
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.007	0.993	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.006	0.993	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.006	0.994	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.006	0.994	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.006	0.994	0.000
S50 Superficial injury of forearm	0.000	0.994	0.006
E04 Other non-toxic goitre	0.006	0.994	0.000
N64.8 Other specified disorders of breast	0.006	0.994	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.006	0.994	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.006	0.994	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.994	0.006
E04.0 Non-toxic diffuse goitre	0.005	0.995	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.995	0.005
S50.1 Contusion of other and unspecified parts of forearm	0.000	0.995	0.005
I44.7 Left bundle-branch block, unspecified	0.005	0.995	0.000
J94.8 Other specified pleural conditions	0.000	0.995	0.005
S50.7 Multiple superficial injuries of forearm	0.000	0.995	0.005
E04.8 Other specified non-toxic goitre	0.004	0.995	0.000
S50.8 Other superficial injuries of forearm	0.000	0.995	0.005
S82.4 Fracture of fibula alone	0.005	0.995	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.996	0.004
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.004	0.996	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.000	0.996	0.004
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.996	0.004
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.996	0.004
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.996	0.004
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.996	0.004
Y51.1 Other parasympathomimetics [cholinergics]	0.000	0.996	0.004
Y51.0 Anticholinesterase agents	0.000	0.996	0.004
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.000	0.996	0.004
Z29.0 Isolation	0.000	0.996	0.004
I44.1 Atrioventricular block, second degree	0.004	0.996	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.996	0.004
F31 Bipolar affective disorder	0.004	0.996	0.000
Z29.1 Prophylactic immunotherapy	0.000	0.996	0.004
F31.0 Bipolar affective disorder, current episode hypomanic	0.004	0.996	0.000
C73 Malignant neoplasm of thyroid gland	0.004	0.996	0.000
Z29 Need for other prophylactic measures	0.000	0.996	0.004
S82.41 Fracture of fibula alone (open)	0.003	0.996	0.000
F31.7 Bipolar affective disorder, currently in remission	0.003	0.996	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.003	0.997	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.003	0.997	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.003	0.997	0.000
H53.8 Other visual disturbances	0.000	0.997	0.003
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.003	0.997	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.003	0.997	0.000
Z51.8 Other specified medical care	0.003	0.997	0.000
H53.4 Visual field defects	0.000	0.997	0.003
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.003	0.997	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.003	0.997	0.000
F33 Recurrent depressive disorder	0.003	0.997	0.000
Z29.9 Prophylactic measure, unspecified	0.000	0.997	0.003
I44 Atrioventricular and left bundle-branch block	0.003	0.997	0.000
K12.1 Other forms of stomatitis	0.003	0.997	0.000
J94 Other pleural conditions	0.000	0.997	0.003
I44.0 Atrioventricular block, first degree	0.003	0.997	0.000
T18.1 Foreign body in oesophagus	0.000	0.997	0.003
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.997	0.003
H53 Visual disturbances	0.000	0.997	0.003
F33.1 Recurrent depressive disorder, current episode moderate	0.003	0.997	0.000
E07.9 Disorder of thyroid, unspecified	0.003	0.997	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.997	0.003
J94.2 Haemothorax	0.000	0.997	0.003
Q39.4 Oesophageal web	0.003	0.997	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.002	0.997	0.000
S91.3 Open wound of other parts of foot	0.000	0.997	0.002
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.003	0.997	0.000
K65.0 Acute peritonitis	0.002	0.998	0.000
H53.1 Subjective visual disturbances	0.000	0.998	0.002
T85 Complications of other internal prosthetic devices, implants and grafts	0.000	0.998	0.002
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.002	0.998	0.000
T85.2 Mechanical complication of intraocular lens	0.000	0.998	0.002
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.998	0.002
J94.1 Fibrothorax	0.000	0.998	0.002
F33.8 Other recurrent depressive disorders	0.002	0.998	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
I44.5 Left posterior fascicular block	0.002	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.002	0.998	0.000
J94.9 Pleural condition, unspecified	0.000	0.998	0.002
J94.0 Chylous effusion	0.000	0.998	0.002
H55-H59 Other disorders of eye and adnexa	0.002	0.998	0.000
E07 Other disorders of thyroid	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.002	0.998	0.000
K65-K67 Diseases of peritoneum	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
H53.6 Night blindness	0.000	0.998	0.002
H53.5 Colour vision deficiencies	0.000	0.998	0.002
H53.3 Other disorders of binocular vision	0.000	0.998	0.002
O14.1 Severe preeclampsia	0.002	0.998	0.000
Y79.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
R42 Dizziness and giddiness	0.002	0.998	0.000
F30-F39 Mood [affective] disorders	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
M93.9 Osteochondropathy, unspecified	0.000	0.998	0.002
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
H53.9 Visual disturbance, unspecified	0.000	0.998	0.002
I44.4 Left anterior fascicular block	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.002	0.998	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.000	0.998	0.002
I44.3 Other and unspecified atrioventricular block	0.002	0.998	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.000	0.998	0.002
H54.0 Blindness, both eyes	0.000	0.998	0.002
Z29.8 Other specified prophylactic measures	0.000	0.998	0.002
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.002	0.998	0.000
O14.0 Moderate preeclampsia	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
Y76.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
G71.1 Myotonic disorders	0.002	0.998	0.000
S40.0 Contusion of shoulder and upper arm	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
F38 Other mood [affective] disorders	0.002	0.998	0.000
H92.0 Otalgia	0.000	0.998	0.002
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
C50.8 Overlapping lesion of breast	0.002	0.998	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.998	0.002
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.000	0.998	0.002
Y77.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.998	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.998	0.000
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
R09.0 Asphyxia	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
Q31.3 Laryngocele	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
F38.0 Other single mood [affective] disorders	0.002	0.998	0.000
Q39.6 Diverticulum of oesophagus	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.002
C02.9 Tongue, unspecified	0.002	0.998	0.000
E07.1 Dyshormogenetic goitre	0.002	0.998	0.000
E07.0 Hypersecretion of calcitonin	0.002	0.998	0.000
N92.1 Excessive and frequent menstruation with irregular cycle	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.002	0.998	0.000
Q31.0 Web of larynx	0.002	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
R60.0 Localised oedema	0.002	0.998	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
O30.0 Twin pregnancy	0.002	0.998	0.000
Z37.2 Twins, both liveborn	0.002	0.998	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.000	0.998	0.002
J30.4 Allergic rhinitis, unspecified	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.002	0.998	0.000
I44.6 Other and unspecified fascicular block	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
H53.2 Diplopia	0.000	0.998	0.002
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
F39 Unspecified mood [affective] disorder	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
F38.8 Other specified mood [affective] disorders	0.002	0.998	0.000
H54.5 Low vision, one eye	0.000	0.998	0.002
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
F30 Manic episode	0.002	0.998	0.000
Q43.7 Persistent cloaca	0.002	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.998	0.000
Q43.5 Ectopic anus	0.002	0.998	0.000
Q43.4 Duplication of intestine	0.002	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y79.0 Diagnostic and monitoring devices	0.002	0.998	0.000
C01 Malignant neoplasm of base of tongue	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
Q77.4 Achondroplasia	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
E00-E07 Disorders of thyroid gland	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.002	0.998	0.000
F38.1 Other recurrent mood [affective] disorders	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.998	0.002
C12 Malignant neoplasm of pyriform sinus	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.001	0.998	0.000
Q31.9 Congenital malformation of larynx, unspecified	0.001	0.998	0.000
Q31.8 Other congenital malformations of larynx	0.001	0.998	0.000
Q31.5 Congenital laryngomalacia	0.001	0.998	0.000
Q31.4 Congenital laryngeal stridor	0.001	0.998	0.000
Q31.2 Laryngeal hypoplasia	0.001	0.998	0.000
Q31.1 Congenital subglottic stenosis	0.001	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.1 Congenital hiatus hernia	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
Q44.4 Choledochal cyst	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
Q83.3 Accessory nipple	0.002	0.998	0.000
S01.0 Open wound of scalp	0.002	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.001	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.001	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.001	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.001	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.001	0.998	0.000
Q52.3 Imperforate hymen	0.001	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.001	0.998	0.000
Q52.1 Doubling of vagina	0.001	0.998	0.000
Q52.0 Congenital absence of vagina	0.001	0.998	0.000
X47.0 Home	0.002	0.998	0.000
G71 Primary disorders of muscles	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.001	0.998	0.000
D26.9 Uterus, unspecified	0.000	0.998	0.002
Q24.0 Dextrocardia	0.002	0.998	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.000	0.998	0.002
C07 Malignant neoplasm of parotid gland	0.002	0.998	0.000
H54 Blindness and low vision	0.000	0.998	0.002
Q05 Spina bifida	0.001	0.998	0.001
Q34 Other congenital malformations of respiratory system	0.001	0.998	0.000
Q33 Congenital malformations of lung	0.001	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.001	0.998	0.000
Q30 Congenital malformations of nose	0.001	0.998	0.000
Q54 Hypospadias	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Y71 Cardiovascular devices associated with adverse incidents	0.002	0.998	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.002	0.998	0.000
G54.6 Phantom limb syndrome with pain	0.002	0.998	0.000
Q24.6 Congenital heart block	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.001	0.998	0.000
Q76.7 Congenital malformation of sternum	0.001	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.001	0.998	0.000
Q76.5 Cervical rib	0.001	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.001	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.001	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.001	0.998	0.000
N10 Acute tubulo-interstitial nephritis	0.002	0.998	0.000
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.001	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.001	0.998	0.000
Q78.6 Multiple congenital exostoses	0.001	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.001	0.998	0.000
Q78.4 Enchondromatosis	0.001	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.001	0.998	0.000
Q78.2 Osteopetrosis	0.001	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.001	0.998	0.000
Q83.1 Accessory breast	0.002	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.001	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.001	0.998	0.000
Q05.9 Spina bifida, unspecified	0.000	0.998	0.001
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.998	0.000
Q68.3 Congenital bowing of femur	0.001	0.998	0.000
Q68.2 Congenital deformity of knee	0.001	0.998	0.000
Q68.1 Congenital deformity of hand	0.001	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.001	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.001	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.001	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.001	0.998	0.000
Q77.5 Diastrophic dysplasia	0.001	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.001	0.998	0.000
Q77.2 Short rib syndrome	0.001	0.998	0.000
Q77.1 Thanatophoric short stature	0.001	0.998	0.000
Q77.0 Achondrogenesis	0.001	0.998	0.000
Y76.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y76.3 Surgical instruments, materials and devices (including sutures)	0.001	0.998	0.000
Y76.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y76.0 Diagnostic and monitoring devices	0.001	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.001	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.001	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.001	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.001	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.001	0.998	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.001	0.998	0.000
K67.3 Tuberculous peritonitis	0.001	0.998	0.000
K67.2 Syphilitic peritonitis	0.001	0.998	0.000
K67.1 Gonococcal peritonitis	0.001	0.998	0.000
K67.0 Chlamydial peritonitis	0.001	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.001	0.998	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.001	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.001	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.001	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.001	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.001	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.001	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.001	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.001	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.001	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.001	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.001	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.001	0.998	0.000
Q90.9 Down's syndrome, unspecified	0.001	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.001	0.998	0.000
R94.3 Abnormal results of cardiovascular function studies	0.000	0.998	0.002
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.000	0.998	0.002
Y71.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
Y77.8 Miscellaneous devices, not elsewhere classified	0.001	0.998	0.000
Y77.2 Prosthetic and other implants, materials and accessory devices	0.001	0.998	0.000
Y77.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.998	0.000
Y77.0 Diagnostic and monitoring devices	0.001	0.998	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.001	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.001	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
O14.2 HELLP syndrome	0.001	0.998	0.000
Q83.8 Other congenital malformations of breast	0.001	0.998	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.001	0.998	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.001	0.998	0.000
Q35 Cleft palate	0.001	0.998	0.000
H53-H54 Visual disturbances and blindness	0.000	0.998	0.002
C14.0 Pharynx, unspecified	0.001	0.998	0.000
F30.1 Mania without psychotic symptoms	0.001	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.001	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.001	0.998	0.000
Q45.1 Annular pancreas	0.001	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.001	0.998	0.000
Q69.9 Polydactyly, unspecified	0.001	0.998	0.000
Q69.2 Accessory toe(s)	0.001	0.998	0.000
Q69.1 Accessory thumb(s)	0.001	0.998	0.000
Q69.0 Accessory finger(s)	0.001	0.998	0.000
Q70.9 Syndactyly, unspecified	0.001	0.998	0.000
Q70.4 Polysyndactyly	0.001	0.998	0.000
Q70.3 Webbed toes	0.001	0.998	0.000
Q70.2 Fused toes	0.001	0.998	0.000
Q70.1 Webbed fingers	0.001	0.998	0.000
Q70.0 Fused fingers	0.001	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.001	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.001	0.998	0.000
Q71.6 Lobster-claw hand	0.001	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.001	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.001	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.001	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.001	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.001	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.001	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.001	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.001	0.998	0.000
Q72.7 Split foot	0.001	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.001	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.001	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.001	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.001	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.001	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.001	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.001	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.001	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.001	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.001	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.001	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.001	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.001	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.001	0.998	0.000
Q75.3 Macrocephaly	0.001	0.998	0.000
Q75.2 Hypertelorism	0.001	0.998	0.000
Q75.1 Craniofacial dysostosis	0.001	0.998	0.000
Q75.0 Craniosynostosis	0.001	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.001	0.998	0.000
F34 Persistent mood [affective] disorders	0.001	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.001	0.998	0.000
Q65.9 Congenital deformity of hip, unspecified	0.001	0.998	0.000
Q65.6 Unstable hip	0.001	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.001	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.001	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.001	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.001	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.001	0.998	0.000
Q83.9 Congenital malformation of breast, unspecified	0.001	0.998	0.000
Q83.2 Absent nipple	0.001	0.998	0.000
Q83.0 Congenital absence of breast with absent nipple	0.001	0.998	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.001	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.002	0.998	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.001	0.998	0.000
Y81 General- and plastic-surgery devices associated with adverse incidents	0.001	0.998	0.000
Y80 Physical medicine devices associated with adverse incidents	0.001	0.998	0.000
Y78 Radiological devices associated with adverse incidents	0.001	0.998	0.000
Y75 Neurological devices associated with adverse incidents	0.001	0.998	0.000
Y74 General hospital and personal-use devices associated with adverse incidents	0.001	0.998	0.000
Y72 Otorhinolaryngological devices associated with adverse incidents	0.001	0.998	0.000
Y70 Anaesthesiology devices associated with adverse incidents	0.001	0.998	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.002	0.998	0.000
F30.8 Other manic episodes	0.001	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.001	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.001	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.001	0.998	0.000
Q53.0 Ectopic testis	0.001	0.998	0.000
Q99.8 Other specified chromosome abnormalities	0.001	0.998	0.000
Q03 Congenital hydrocephalus	0.001	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.998	0.000
T82.3 Mechanical complication of other vascular grafts	0.000	0.998	0.002
E06 Thyroiditis	0.001	0.998	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.001	0.998	0.000
E00 Congenital iodine-deficiency syndrome	0.001	0.998	0.000
Q37 Cleft palate with cleft lip	0.001	0.998	0.000
Q36 Cleft lip	0.001	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.001	0.998	0.000
Q84 Other congenital malformations of integument	0.001	0.998	0.000
Q81 Epidermolysis bullosa	0.001	0.998	0.000
Q80 Congenital ichthyosis	0.001	0.998	0.000
K66.9 Disorder of peritoneum, unspecified	0.001	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.001	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.001	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q90.2 Trisomy 21, translocation	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations