TreeWAS – Variant ID: rs2223089

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.127	0.873	0.000
I25 Chronic ischaemic heart disease	0.085	0.915	0.000
I20.0 Unstable angina	0.084	0.916	0.000
I20 Angina pectoris	0.080	0.920	0.000
I20-I25 Ischaemic heart diseases	0.078	0.922	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.925	0.075
I20.9 Angina pectoris, unspecified	0.069	0.931	0.000
I25.2 Old myocardial infarction	0.068	0.932	0.000
I25.4 Coronary artery aneurysm	0.067	0.933	0.000
I24 Other acute ischaemic heart diseases	0.064	0.936	0.000
I25.6 Silent myocardial ischaemia	0.061	0.938	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.060	0.940	0.000
I20.8 Other forms of angina pectoris	0.060	0.940	0.000
I25.5 Ischaemic cardiomyopathy	0.056	0.943	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.056	0.944	0.000
I25.3 Aneurysm of heart	0.055	0.945	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.055	0.945	0.000
I23 Certain current complications following acute myocardial infarction	0.054	0.946	0.000
I24.8 Other forms of acute ischaemic heart disease	0.053	0.947	0.000
I21 Acute myocardial infarction	0.052	0.948	0.000
K57 Diverticular disease of intestine	0.000	0.951	0.049
I24.1 Dressler's syndrome	0.046	0.954	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.954	0.046
I21.9 Acute myocardial infarction, unspecified	0.044	0.956	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.043	0.957	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.042	0.958	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.039	0.961	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.039	0.961	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.039	0.961	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.039	0.961	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.039	0.961	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.039	0.961	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.039	0.961	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.000	0.962	0.038
I22 Subsequent myocardial infarction	0.037	0.962	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.037	0.963	0.000
I23.8 Other current complications following acute myocardial infarction	0.036	0.963	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.963	0.037
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.000	0.965	0.035
I21.3 Acute transmural myocardial infarction of unspecified site	0.034	0.966	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.033	0.967	0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.968	0.032
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.000	0.969	0.030
I20.1 Angina pectoris with documented spasm	0.029	0.971	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.000	0.972	0.028
I21.2 Acute transmural myocardial infarction of other sites	0.027	0.973	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.027	0.973	0.000
I22.8 Subsequent myocardial infarction of other sites	0.026	0.973	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.021	0.979	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.020	0.980	0.000
I21.4 Acute subendocardial myocardial infarction	0.013	0.987	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.010	0.990	0.000
R49.0 Dysphonia	0.008	0.992	0.000
N30.9 Cystitis, unspecified	0.000	0.992	0.008
C67.9 Bladder, unspecified	0.000	0.993	0.007
N81.3 Complete uterovaginal prolapse	0.000	0.994	0.006
N81.6 Rectocele	0.000	0.994	0.006
H61.0 Perichondritis of external ear	0.006	0.994	0.000
N81.5 Vaginal enterocele	0.000	0.994	0.006
N81 Female genital prolapse	0.000	0.994	0.006
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.994	0.006
N81.4 Uterovaginal prolapse, unspecified	0.000	0.995	0.005
C67 Malignant neoplasm of bladder	0.000	0.995	0.005
H61 Other disorders of external ear	0.005	0.995	0.000
R49 Voice disturbances	0.005	0.995	0.000
C67.5 Bladder neck	0.000	0.995	0.005
N81.9 Female genital prolapse, unspecified	0.000	0.995	0.004
R03.1 Nonspecific low blood-pressure reading	0.005	0.995	0.000
C67.1 Dome of bladder	0.000	0.996	0.004
J38.4 Oedema of larynx	0.004	0.996	0.000
C67.4 Posterior wall of bladder	0.000	0.996	0.004
N81.1 Cystocele	0.000	0.996	0.004
C67.3 Anterior wall of bladder	0.000	0.996	0.004
I67.1 Cerebral aneurysm, nonruptured	0.000	0.996	0.004
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.004	0.996	0.000
R10.1 Pain localised to upper abdomen	0.000	0.996	0.004
H61.3 Acquired stenosis of external ear canal	0.004	0.996	0.000
E83.1 Disorders of iron metabolism	0.000	0.996	0.004
J38.3 Other diseases of vocal cords	0.004	0.996	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.996	0.004
J38.1 Polyp of vocal cord and larynx	0.004	0.996	0.000
C67.7 Urachus	0.000	0.996	0.004
H61.1 Non-infective disorders of pinna	0.004	0.996	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.004	0.996	0.000
N81.0 Female urethrocele	0.000	0.996	0.004
H61.8 Other specified disorders of external ear	0.004	0.996	0.000
C67.6 Ureteric orifice	0.000	0.996	0.004
C67.0 Trigone of bladder	0.000	0.996	0.004
N81.8 Other female genital prolapse	0.000	0.996	0.004
R49.2 Hypernasality and hyponasality	0.003	0.996	0.000
R49.1 Aphonia	0.003	0.996	0.000
H61.9 Disorder of external ear, unspecified	0.003	0.996	0.000
C67.8 Overlapping lesion of bladder	0.000	0.996	0.003
H61.2 Impacted cerumen	0.004	0.996	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.004	0.996	0.000
R49.8 Other and unspecified voice disturbances	0.003	0.997	0.000
J38.5 Laryngeal spasm	0.003	0.997	0.000
J38.0 Paralysis of vocal cords and larynx	0.003	0.997	0.000
F45.8 Other somatoform disorders	0.003	0.997	0.000
C67.2 Lateral wall of bladder	0.000	0.997	0.003
J38.6 Stenosis of larynx	0.003	0.997	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.003	0.997	0.000
Z04.8 Examination and observation for other specified reasons	0.000	0.997	0.003
J38.2 Nodules of vocal cords	0.003	0.997	0.000
N13.8 Other obstructive and reflux uropathy	0.003	0.997	0.000
Z04.3 Examination and observation following other accident	0.000	0.997	0.003
N30.1 Interstitial cystitis (chronic)	0.000	0.997	0.003
J38.7 Other diseases of larynx	0.003	0.997	0.000
N30 Cystitis	0.000	0.997	0.003
J37.0 Chronic laryngitis	0.003	0.997	0.000
G40.9 Epilepsy, unspecified	0.000	0.997	0.003
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.997	0.003
H60-H62 Diseases of external ear	0.003	0.997	0.000
S62.61 Fracture of other finger (open)	0.000	0.997	0.003
C44.6 Skin of upper limb, including shoulder	0.003	0.997	0.000
N13.3 Other and unspecified hydronephrosis	0.002	0.998	0.000
N99.2 Postprocedural adhesions of vagina	0.000	0.998	0.002
H60 Otitis externa	0.002	0.998	0.000
N13 Obstructive and reflux uropathy	0.002	0.998	0.000
Z04 Examination and observation for other reasons	0.000	0.998	0.002
I63.9 Cerebral infarction, unspecified	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
R47.1 Dysarthria and anarthria	0.002	0.998	0.000
H60.5 Acute otitis externa, non-infective	0.002	0.998	0.000
N30.8 Other cystitis	0.000	0.998	0.002
N30.4 Irradiation cystitis	0.000	0.998	0.002
H60.8 Other otitis externa	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.000	0.998	0.002
N99.1 Postprocedural urethral stricture	0.000	0.998	0.002
F10.0 Acute intoxication	0.002	0.998	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.002	0.998	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.998	0.002
Z04.5 Examination and observation following other inflicted injury	0.000	0.998	0.002
H62 Disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
H60.3 Other infective otitis externa	0.002	0.998	0.000
Z04.9 Examination and observation for unspecified reason	0.000	0.998	0.002
H60.1 Cellulitis of external ear	0.002	0.998	0.000
S82.3 Fracture of lower end of tibia	0.000	0.998	0.002
S42.00 Fracture of clavicle (closed)	0.002	0.998	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.998	0.002
R47-R49 Symptoms and signs involving speech and voice	0.002	0.998	0.000
N99.0 Postprocedural renal failure	0.000	0.998	0.002
H60.4 Cholesteatoma of external ear	0.002	0.998	0.000
H60.2 Malignant otitis externa	0.002	0.998	0.000
H60.0 Abscess of external ear	0.002	0.998	0.000
N39.4 Other specified urinary incontinence	0.002	0.998	0.000
Z04.6 General psychiatric examination, requested by authority	0.000	0.998	0.002
Z04.4 Examination and observation following alleged rape and seduction	0.000	0.998	0.002
Z04.2 Examination and observation following work accident	0.000	0.998	0.002
Z04.0 Blood-alcohol and blood-drug test	0.000	0.998	0.002
I63.8 Other cerebral infarction	0.002	0.998	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.002	0.998	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.002	0.998	0.000
H93.1 Tinnitus	0.000	0.998	0.002
N13.6 Pyonephrosis	0.002	0.998	0.000
N30.2 Other chronic cystitis	0.000	0.998	0.002
N99.5 Malfunction of external stoma of urinary tract	0.000	0.998	0.002
A49.0 Staphylococcal infection, unspecified	0.002	0.998	0.000
O42.9 Premature rupture of membranes, unspecified	0.002	0.998	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.002	0.998	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H62.2 Otitis externa in mycoses	0.002	0.998	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.002	0.998	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
M75.0 Adhesive capsulitis of shoulder	0.002	0.998	0.000
M79.66 Pain in limb (Lower leg)	0.000	0.998	0.002
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.002	0.998	0.000
N30.0 Acute cystitis	0.000	0.998	0.002
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.002	0.998	0.000
C64-C68 Malignant neoplasms of urinary tract	0.000	0.998	0.002
N30.3 Trigonitis	0.000	0.998	0.002
W44.0 Home	0.000	0.998	0.002
I63 Cerebral infarction	0.002	0.998	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.002	0.998	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.002	0.998	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.998	0.002
I69.1 Sequelae of intracerebral haemorrhage	0.002	0.998	0.000
K62.6 Ulcer of anus and rectum	0.000	0.998	0.002
R47 Speech disturbances, not elsewhere classified	0.002	0.998	0.000
F32.9 Depressive episode, unspecified	0.000	0.998	0.002
G24.9 Dystonia, unspecified	0.000	0.998	0.002
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.998	0.001
H10.9 Conjunctivitis, unspecified	0.002	0.998	0.000
Z74.0 Reduced mobility	0.002	0.998	0.000
C66 Malignant neoplasm of ureter	0.000	0.998	0.002
M79.65 Pain in limb (Pelvic region and thigh)	0.000	0.998	0.002
D03.7 Melanoma in situ of lower limb, including hip	0.002	0.998	0.000
F32.1 Moderate depressive episode	0.000	0.998	0.002
F32.0 Mild depressive episode	0.000	0.998	0.002
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.002	0.998	0.000
G40 Epilepsy	0.000	0.998	0.002
M48.09 Spinal stenosis (Site unspecified)	0.002	0.998	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.002	0.998	0.000
L89.1 Stage II decubitus ulcer	0.000	0.998	0.002
F32 Depressive episode	0.000	0.998	0.002
M77.47 Metatarsalgia-Ankle/Foot	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.000	0.998	0.001
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
U80.8 Agent resistant to other penicillin-related antibiotic	0.001	0.998	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.998	0.002
R48.8 Other and unspecified symbolic dysfunctions	0.001	0.998	0.000
R48.2 Apraxia	0.001	0.998	0.000
R48.1 Agnosia	0.001	0.998	0.000
R48.0 Dyslexia and alexia	0.001	0.998	0.000
S91.3 Open wound of other parts of foot	0.000	0.998	0.001
Z04.1 Examination and observation following transport accident	0.000	0.998	0.001
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.998	0.001
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.001	0.998	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.001	0.998	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.001	0.998	0.000
M22.4 Chondromalacia patellae	0.000	0.998	0.001
U80.1 Methicillin resistant agent	0.001	0.998	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.998	0.001
F45 Somatoform disorders	0.001	0.998	0.000
J92 Pleural plaque	0.000	0.998	0.001
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.999	0.001
G45.4 Transient global amnesia	0.000	0.999	0.001
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.999	0.001
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.999	0.001
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.001	0.999	0.000
N11.1 Chronic obstructive pyelonephritis	0.001	0.999	0.000
N43.3 Hydrocele, unspecified	0.000	0.999	0.001
Z50.8 Care involving use of rehabilitation procedures	0.001	0.999	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.001	0.999	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.999	0.001
M93.9 Osteochondropathy, unspecified	0.001	0.999	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.999	0.001
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.999	0.001
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.999	0.001
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.001	0.999	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.999	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.001	0.999	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.001	0.999	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.001	0.999	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.001	0.999	0.000
I78.1 Naevus, nonneoplastic	0.001	0.999	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.999	0.001
M22.8 Other disorders of patella	0.000	0.999	0.001
N13.4 Hydroureter	0.001	0.999	0.000
C65 Malignant neoplasm of renal pelvis	0.000	0.999	0.001
C68.9 Urinary organ, unspecified	0.000	0.999	0.001
C68.8 Overlapping lesion of urinary organs	0.000	0.999	0.001
C68.1 Paraurethral glands	0.000	0.999	0.001
C68.0 Urethra	0.000	0.999	0.001
F45.9 Somatoform disorder, unspecified	0.001	0.999	0.000
F45.4 Persistent somatoform pain disorder	0.001	0.999	0.000
F45.2 Hypochondriacal disorder	0.001	0.999	0.000
F45.1 Undifferentiated somatoform disorder	0.001	0.999	0.000
F45.0 Somatisation disorder	0.001	0.999	0.000
G40.5 Special epileptic syndromes	0.000	0.999	0.001
I61 Intracerebral haemorrhage	0.001	0.999	0.000
N11 Chronic tubulo-interstitial nephritis	0.001	0.999	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.999	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.001	0.999	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.001	0.999	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.001	0.999	0.000
U80 Agent resistant to penicillin and related antibiotics	0.001	0.999	0.000
A49.1 Streptococcal infection, unspecified	0.001	0.999	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.001	0.999	0.000
I70.0 Atherosclerosis of aorta	0.001	0.999	0.000
N10-N16 Renal tubulo-interstitial diseases	0.001	0.999	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.999	0.001
O14.9 Preeclampsia, unspecified	0.001	0.999	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.001	0.999	0.000
F32.8 Other depressive episodes	0.000	0.999	0.001
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.999	0.001
F45.3 Somatoform autonomic dysfunction	0.001	0.999	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.001	0.999	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.999	0.001
I61.8 Other intracerebral haemorrhage	0.001	0.999	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.001	0.999	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.999	0.001
H21.0 Hyphaema	0.001	0.999	0.000
H60.9 Otitis externa, unspecified	0.001	0.999	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.001	0.999	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.001	0.999	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.001	0.999	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.001	0.999	0.000
Z99.3 Dependence on wheelchair	0.000	0.999	0.001
I69 Sequelae of cerebrovascular disease	0.001	0.999	0.000
L60.0 Ingrowing nail	0.001	0.999	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.999	0.001
S80.0 Contusion of knee	0.000	0.999	0.001
I70 Atherosclerosis	0.001	0.999	0.000
J37 Chronic laryngitis and laryngotracheitis	0.001	0.999	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.001	0.999	0.000
F10.4 Withdrawal state with delirium	0.001	0.999	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.999	0.001
G40.8 Other epilepsy	0.000	0.999	0.001
I70.1 Atherosclerosis of renal artery	0.001	0.999	0.000
U89.8 Agent resistant to other single specified antibiotic	0.001	0.999	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.001	0.999	0.000
N15 Other renal tubulo-interstitial diseases	0.001	0.999	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.001	0.999	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.001	0.999	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.999	0.001
H20.9 Iridocyclitis, unspecified	0.001	0.999	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.001	0.999	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.001	0.999	0.000
L60.9 Nail disorder, unspecified	0.001	0.999	0.000
T46.1 Calcium-channel blockers	0.001	0.999	0.000
F31 Bipolar affective disorder	0.000	0.999	0.001
D11.7 Other major salivary glands	0.001	0.999	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.001	0.999	0.000
R41.0 Disorientation, unspecified	0.000	0.999	0.001
S80.9 Superficial injury of lower leg, unspecified	0.000	0.999	0.001
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
U80.0 Penicillin resistant agent	0.001	0.999	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.001	0.999	0.000
H21.8 Other specified disorders of iris and ciliary body	0.001	0.999	0.000
I70.9 Generalised and unspecified atherosclerosis	0.001	0.999	0.000
I70.8 Atherosclerosis of other arteries	0.001	0.999	0.000
J37.1 Chronic laryngotracheitis	0.001	0.999	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.001	0.999	0.000
N14.3 Nephropathy induced by heavy metals	0.001	0.999	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.001	0.999	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.001	0.999	0.000
N14.0 Analgesic nephropathy	0.001	0.999	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.001	0.999	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.001	0.999	0.000
N15.1 Renal and perinephric abscess	0.001	0.999	0.000
N15.0 Balkan nephropathy	0.001	0.999	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.001	0.999	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.001	0.999	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.001	0.999	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.001	0.999	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.001	0.999	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.001	0.999	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.001	0.999	0.000
D26.1 Corpus uteri	0.000	0.999	0.001
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.999	0.001
H21.9 Disorder of iris and ciliary body, unspecified	0.001	0.999	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.001	0.999	0.000
L60.8 Other nail disorders	0.001	0.999	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.999	0.000
S83.2 Tear of meniscus, current	0.000	0.999	0.001
Z42.9 Follow-up care involving plastic surgery, unspecified	0.001	0.999	0.000
N99-N99 Other disorders of the genitourinary system	0.000	0.999	0.001
F31.8 Other bipolar affective disorders	0.000	0.999	0.001
F31.7 Bipolar affective disorder, currently in remission	0.000	0.999	0.001
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.999	0.001
K35.2 Acute appendicitis with generalized peritonitis	0.000	0.999	0.001
L60.3 Nail dystrophy	0.001	0.999	0.000
M48.0 Spinal stenosis	0.001	0.999	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.001	0.999	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.999	0.001
S42.0 Fracture of clavicle	0.001	0.999	0.000
S62.6 Fracture of other finger	0.000	0.999	0.001
S80 Superficial injury of lower leg	0.000	0.999	0.001
I70.81 Atherosclerosis of other arteries (with gangrene)	0.001	0.999	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.001	0.999	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.001	0.999	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.001	0.999	0.000
A87.9 Viral meningitis, unspecified	0.000	0.999	0.001
F10.1 Harmful use	0.001	0.999	0.000
G59.0 Diabetic mononeuropathy	0.001	0.999	0.000
H15.0 Scleritis	0.001	0.999	0.000
H65.3 Chronic mucoid otitis media	0.000	0.999	0.001
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.001	0.999	0.000
T78.3 Angioneurotic oedema	0.001	0.999	0.000
H21 Other disorders of iris and ciliary body	0.001	0.999	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.001	0.999	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.001	0.999	0.000
M48.04 Spinal stenosis (Thoracic region)	0.001	0.999	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.001	0.999	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M79.79 Fibromyalgia (Site unspecified)	0.000	0.999	0.001
S42.01 Fracture of clavicle (open)	0.001	0.999	0.000
F10.6 Amnesic syndrome	0.001	0.999	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.999	0.001
L60.2 Onychogryphosis	0.001	0.999	0.000
O14.1 Severe preeclampsia	0.001	0.999	0.000
X78.0 Home	0.000	0.999	0.001
K35 Acute appendicitis	0.000	0.999	0.001
M79.00 Rheumatism, unspecified (Multiple sites)	0.000	0.999	0.001
M79.60 Pain in limb (Multiple sites)	0.000	0.999	0.001
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.999	0.001
H16.9 Keratitis, unspecified	0.001	0.999	0.000
H21.4 Pupillary membranes	0.001	0.999	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.001	0.999	0.000
H21.2 Degeneration of iris and ciliary body	0.001	0.999	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.001	0.999	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.001	0.999	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.001	0.999	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.001	0.999	0.000
O36.6 Maternal care for excessive foetal growth	0.001	0.999	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
T46.7 Peripheral vasodilators	0.001	0.999	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
L60 Nail disorders	0.001	0.999	0.000
M79.70 Fibromyalgia (Multiple sites)	0.000	0.999	0.001
S82.60 Fracture of lateral malleolus (closed)	0.000	0.999	0.001
A49.9 Bacterial infection, unspecified	0.001	0.999	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.999	0.001
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.999	0.001
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.999	0.001
M77.4 Metatarsalgia	0.001	0.999	0.000
M89.9 Disorder of bone, unspecified	0.000	0.999	0.001
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.999	0.001
A49 Bacterial infection of unspecified site	0.001	0.999	0.000
Z42 Follow-up care involving plastic surgery	0.001	0.999	0.000
M77.49 Metatarsalgia-Site unspec	0.001	0.999	0.000
M77.48 Metatarsalgia-Other	0.001	0.999	0.000
M77.46 Metatarsalgia-Lower Leg	0.001	0.999	0.000
M77.45 Metatarsalgia-Pelvic/Thigh	0.001	0.999	0.000
M77.44 Metatarsalgia-Hand	0.001	0.999	0.000
M77.43 Metatarsalgia-Forearm	0.001	0.999	0.000
M77.42 Metatarsalgia-Upper arm	0.001	0.999	0.000
M77.41 Metatarsalgia-Shldr region	0.001	0.999	0.000
M77.40 Metatarsalgia-Mult sites	0.001	0.999	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.999	0.001
M89.98 Disorder of bone, unspecified (Other)	0.000	0.999	0.001
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.999	0.001
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.999	0.001
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.999	0.001
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.999	0.001
S82.00 Fracture of patella (closed)	0.000	0.999	0.001
A49.3 Mycoplasma infection, unspecified	0.001	0.999	0.000
A49.2 Haemophilus influenzae infection, unspecified	0.001	0.999	0.000
C32.0 Glottis	0.000	0.999	0.001
I82.8 Embolism and thrombosis of other specified veins	0.000	0.999	0.001
J30.4 Allergic rhinitis, unspecified	0.000	0.999	0.001
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.999	0.001
L60.5 Yellow nail syndrome	0.001	0.999	0.000
L60.4 Beau's lines	0.001	0.999	0.000
L60.1 Onycholysis	0.001	0.999	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.001	0.999	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.999	0.001
C62.9 Testis, unspecified	0.001	0.999	0.000
I69.3 Sequelae of cerebral infarction	0.001	0.999	0.000
K02.9 Dental caries, unspecified	0.000	0.999	0.001
S80.8 Other superficial injuries of lower leg	0.000	0.999	0.001
S80.7 Multiple superficial injuries of lower leg	0.000	0.999	0.001
Z42.8 Follow-up care involving plastic surgery of other body part	0.001	0.999	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.999	0.001
F10.9 Unspecified mental and behavioural disorder	0.001	0.999	0.000
F10.8 Other mental and behavioural disorders	0.001	0.999	0.000
F10.7 Residual and late-onset psychotic disorder	0.001	0.999	0.000
F10.5 Psychotic disorder	0.001	0.999	0.000
J20.8 Acute bronchitis due to other specified organisms	0.001	0.999	0.000
J98.1 Pulmonary collapse	0.000	0.999	0.001
R74.8 Abnormal levels of other serum enzymes	0.001	0.999	0.000
S82.6 Fracture of lateral malleolus	0.000	0.999	0.001
S82.0 Fracture of patella	0.000	0.999	0.001
S91.1 Open wound of toe(s) without damage to nail	0.000	0.999	0.001
Z42.1 Follow-up care involving plastic surgery of breast	0.001	0.999	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.001	0.999	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.999	0.001
S82.01 Fracture of patella (open)	0.000	0.999	0.001
S82.61 Fracture of lateral malleolus (open)	0.000	0.999	0.001
F30.9 Manic episode, unspecified	0.000	0.999	0.001
H17.9 Corneal scar and opacity, unspecified	0.001	0.999	0.000
H93.9 Disorder of ear, unspecified	0.000	0.999	0.001
H93.8 Other specified disorders of ear	0.000	0.999	0.001
H93.3 Disorders of acoustic nerve	0.000	0.999	0.001
H93.2 Other abnormal auditory perceptions	0.000	0.999	0.001
H93.0 Degenerative and vascular disorders of ear	0.000	0.999	0.001
I69.0 Sequelae of subarachnoid haemorrhage	0.001	0.999	0.000
I73.8 Other specified peripheral vascular diseases	0.001	0.999	0.000
M79.0 Rheumatism, unspecified	0.000	0.999	0.001
Q51.3 Bicornate uterus	0.000	0.999	0.001
R22.9 Localised swelling, mass and lump, unspecified	0.001	0.999	0.000
H15 Disorders of sclera	0.001	0.999	0.000
M79.08 Rheumatism, unspecified (Other)	0.000	0.999	0.001
M79.07 Rheumatism, unspecified (Ankle and foot)	0.000	0.999	0.001
M79.06 Rheumatism, unspecified (Lower leg)	0.000	0.999	0.001
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M79.04 Rheumatism, unspecified (Hand)	0.000	0.999	0.001
M79.03 Rheumatism, unspecified (Forearm)	0.000	0.999	0.001
M79.02 Rheumatism, unspecified (Upper arm)	0.000	0.999	0.001
M79.01 Rheumatism, unspecified (Shoulder region)	0.000	0.999	0.001
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
S02.50 Fracture of tooth (closed)	0.001	0.999	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.999	0.001
H15.9 Disorder of sclera, unspecified	0.001	0.999	0.000
H15.8 Other disorders of sclera	0.001	0.999	0.000
H15.1 Episcleritis	0.001	0.999	0.000
H16.8 Other keratitis	0.001	0.999	0.000
H16.4 Corneal neovascularisation	0.001	0.999	0.000
H16.3 Interstitial and deep keratitis	0.001	0.999	0.000
H16.2 Keratoconjunctivitis	0.001	0.999	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.001	0.999	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.999	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.999	0.001
K12.3 Oral mucositis (ulcerative)	0.000	0.999	0.001
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.999	0.001
Q85.9 Phakomatosis, unspecified	0.001	0.999	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.001	0.999	0.000
T78.8 Other adverse effects, not elsewhere classified	0.001	0.999	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.001	0.999	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.999	0.000
H16 Keratitis	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations