TreeWAS – Variant ID: rs2229092

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
E03 Other hypothyroidism	0.999	0.001	0.000
E00-E07 Disorders of thyroid gland	0.999	0.001	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.999	0.001	0.000
# Top node	0.999	0.001	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002	0.000
S40-S49 Injuries to the shoulder and upper arm	0.989	0.011	0.000
Chapter VIII Diseases of the ear and mastoid process	0.988	0.012	0.000
Chapter X Diseases of the respiratory system	0.987	0.013	0.000
J30-J39 Other diseases of upper respiratory tract	0.981	0.019	0.000
J32 Chronic sinusitis	0.975	0.025	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.970	0.030	0.000
H65-H75 Diseases of middle ear and mastoid	0.969	0.031	0.000
J40-J47 Chronic lower respiratory diseases	0.966	0.034	0.000
S42 Fracture of shoulder and upper arm	0.962	0.038	0.000
J31.0 Chronic rhinitis	0.961	0.039	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.956	0.044	0.000
J32.9 Chronic sinusitis, unspecified	0.953	0.047	0.000
Chapter XIV Diseases of the genitourinary system	0.952	0.048	0.000
J40 Bronchitis, not specified as acute or chronic	0.952	0.048	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.949	0.051	0.000
S42.0 Fracture of clavicle	0.946	0.054	0.000
H60-H62 Diseases of external ear	0.946	0.054	0.000
M70-M79 Other soft tissue disorders	0.937	0.063	0.000
J47 Bronchiectasis	0.936	0.064	0.000
S42.00 Fracture of clavicle (closed)	0.935	0.065	0.000
M75 Shoulder lesions	0.935	0.065	0.000
M20-M25 Other joint disorders	0.933	0.067	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.932	0.068	0.000
H65 Nonsuppurative otitis media	0.930	0.070	0.000
T66-T78 Other and unspecified effects of external causes	0.927	0.073	0.000
N99-N99 Other disorders of the genitourinary system	0.926	0.074	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.915	0.085	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.912	0.088	0.000
E10-E14 Diabetes mellitus	0.909	0.091	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.907	0.093	0.000
E70-E90 Metabolic disorders	0.904	0.096	0.000
H73 Other disorders of tympanic membrane	0.904	0.096	0.000
H61 Other disorders of external ear	0.903	0.097	0.000
M75.4 Impingement syndrome of shoulder	0.903	0.097	0.000
E11 Non-insulin-dependent diabetes mellitus	0.901	0.099	0.000
N30-N39 Other diseases of urinary system	0.900	0.100	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.896	0.104	0.000
E06 Thyroiditis	0.890	0.110	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.889	0.111	0.000
E78.0 Pure hypercholesterolaemia	0.885	0.115	0.000
S50-S59 Injuries to the elbow and forearm	0.885	0.115	0.000
M75.1 Rotator cuff syndrome	0.884	0.116	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.880	0.120	0.000
J34 Other disorders of nose and nasal sinuses	0.878	0.122	0.000
N39 Other disorders of urinary system	0.876	0.124	0.000
E11.9 Without complications	0.876	0.124	0.000
M86-M90 Other osteopathies	0.876	0.124	0.000
M20 Acquired deformities of fingers and toes	0.875	0.125	0.000
M34 Systemic sclerosis	0.875	0.125	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.872	0.128	0.000
H73.8 Other specified disorders of tympanic membrane	0.857	0.143	0.000
J34.2 Deviated nasal septum	0.855	0.145	0.000
S43.0 Dislocation of shoulder joint	0.851	0.149	0.000
N75 Diseases of Bartholin's gland	0.851	0.149	0.000
T78 Adverse effects, not elsewhere classified	0.850	0.150	0.000
N71 Inflammatory disease of uterus, except cervix	0.849	0.151	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.848	0.152	0.000
H65.2 Chronic serous otitis media	0.846	0.154	0.000
N60-N64 Disorders of breast	0.845	0.155	0.000
H61.0 Perichondritis of external ear	0.841	0.159	0.000
J32.2 Chronic ethmoidal sinusitis	0.839	0.161	0.000
T79-T79 Certain early complications of trauma	0.837	0.163	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.834	0.166	0.000
J60-J70 Lung diseases due to external agents	0.834	0.166	0.000
E07 Other disorders of thyroid	0.829	0.171	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.828	0.172	0.000
E11.3 With ophthalmic complications	0.827	0.173	0.000
N39.3 Stress incontinence	0.827	0.173	0.000
N99.0 Postprocedural renal failure	0.822	0.178	0.000
N39.4 Other specified urinary incontinence	0.819	0.181	0.000
S42.4 Fracture of lower end of humerus	0.814	0.186	0.000
T00-T07 Injuries involving multiple body regions	0.809	0.191	0.000
T78.3 Angioneurotic oedema	0.807	0.192	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.805	0.195	0.000
H61.2 Impacted cerumen	0.805	0.195	0.000
S20-S29 Injuries to the thorax	0.804	0.196	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.804	0.196	0.000
E06.3 Autoimmune thyroiditis	0.802	0.198	0.000
S32 Fracture of lumbar spine and pelvis	0.797	0.203	0.000
S60-S69 Injuries to the wrist and hand	0.797	0.203	0.000
M20.4 Other hammer toe(s) (acquired)	0.795	0.205	0.000
Q80-Q89 Other congenital malformations	0.793	0.207	0.000
J32.8 Other chronic sinusitis	0.791	0.209	0.000
S51 Open wound of forearm	0.790	0.210	0.000
N72 Inflammatory disease of cervix uteri	0.789	0.211	0.000
J30 Vasomotor and allergic rhinitis	0.785	0.215	0.000
M75.5 Bursitis of shoulder	0.782	0.218	0.000
T70 Effects of air pressure and water pressure	0.782	0.218	0.000
H66 Suppurative and unspecified otitis media	0.778	0.222	0.000
Q23 Congenital malformations of aortic and mitral valves	0.778	0.222	0.000
Q50-Q56 Congenital malformations of genital organs	0.777	0.223	0.000
N60 Benign mammary dysplasia	0.776	0.224	0.000
M22 Disorders of patella	0.775	0.225	0.000
E78.5 Hyperlipidaemia, unspecified	0.774	0.226	0.000
Chapter XI Diseases of the digestive system	0.773	0.227	0.000
H65.3 Chronic mucoid otitis media	0.772	0.228	0.000
K50-K52 Noninfective enteritis and colitis	0.771	0.229	0.000
N75.0 Cyst of Bartholin's gland	0.770	0.230	0.000
M60-M63 Disorders of muscles	0.767	0.233	0.000
M77 Other enthesopathies	0.764	0.236	0.000
J32.4 Chronic pansinusitis	0.761	0.239	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.760	0.240	0.000
K50 Crohn's disease [regional enteritis]	0.760	0.240	0.000
M23 Internal derangement of knee	0.757	0.243	0.000
M20.5 Other deformities of toe(s) (acquired)	0.757	0.243	0.000
M75.0 Adhesive capsulitis of shoulder	0.757	0.243	0.000
J42 Unspecified chronic bronchitis	0.756	0.244	0.000
H60 Otitis externa	0.754	0.246	0.000
S40 Superficial injury of shoulder and upper arm	0.751	0.249	0.000
S10-S19 Injuries to the neck	0.751	0.249	0.000
M34.1 CR(E)ST syndrome	0.749	0.251	0.000
N71.1 Chronic inflammatory disease of uterus	0.749	0.251	0.000
J34.3 Hypertrophy of nasal turbinates	0.747	0.253	0.000
J32.1 Chronic frontal sinusitis	0.747	0.253	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.746	0.254	0.000
K50.9 Crohn's disease, unspecified	0.743	0.257	0.000
M86 Osteomyelitis	0.743	0.257	0.000
N63 Unspecified lump in breast	0.740	0.260	0.000
E50-E64 Other nutritional deficiencies	0.739	0.261	0.000
Q24 Other congenital malformations of heart	0.738	0.262	0.000
M75.2 Bicipital tendinitis	0.737	0.263	0.000
M34.8 Other forms of systemic sclerosis	0.733	0.267	0.000
M34.9 Systemic sclerosis, unspecified	0.731	0.269	0.000
N76 Other inflammation of vagina and vulva	0.730	0.270	0.000
S56 Injury of muscle and tendon at forearm level	0.727	0.273	0.000
M75.3 Calcific tendinitis of shoulder	0.725	0.275	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.724	0.276	0.000
M87 Osteonecrosis	0.723	0.277	0.000
S36 Injury of intra-abdominal organs	0.722	0.278	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.721	0.279	0.000
J69 Pneumonitis due to solids and liquids	0.720	0.279	0.000
S90-S99 Injuries to the ankle and foot	0.720	0.280	0.000
E11.6 With other specified complications	0.719	0.281	0.000
Q25 Congenital malformations of great arteries	0.719	0.281	0.000
N60.0 Solitary cyst of breast	0.718	0.282	0.000
S41 Open wound of shoulder and upper arm	0.718	0.282	0.000
E03.8 Other specified hypothyroidism	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.716	0.284	0.000
E00 Congenital iodine-deficiency syndrome	0.716	0.284	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.716	0.284	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.716	0.284	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.716	0.284	0.000
T33-T35 Frostbite	0.715	0.284	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.284	0.000
E79 Disorders of purine and pyrimidine metabolism	0.714	0.286	0.000
M40-M43 Deforming dorsopathies	0.712	0.288	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.712	0.288	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.709	0.291	0.000
Q00-Q07 Congenital malformations of the nervous system	0.709	0.291	0.000
T59 Toxic effect of other gases, fumes and vapours	0.709	0.291	0.000
S48 Traumatic amputation of shoulder and upper arm	0.709	0.291	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.709	0.291	0.000
S44 Injury of nerves at shoulder and upper arm level	0.709	0.291	0.000
S47 Crushing injury of shoulder and upper arm	0.709	0.291	0.000
J31.2 Chronic pharyngitis	0.708	0.291	0.000
E07.9 Disorder of thyroid, unspecified	0.708	0.292	0.000
T58 Toxic effect of carbon monoxide	0.707	0.292	0.000
M23.3 Other meniscus derangements	0.707	0.293	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.707	0.293	0.000
T75 Effects of other external causes	0.704	0.296	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.704	0.296	0.000
E11.2 With renal complications	0.700	0.300	0.000
M22.4 Chondromalacia patellae	0.699	0.301	0.000
J32.3 Chronic sphenoidal sinusitis	0.699	0.301	0.000
K51 Ulcerative colitis	0.699	0.301	0.000
M91-M94 Chondropathies	0.698	0.302	0.000
J31.1 Chronic nasopharyngitis	0.695	0.305	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.695	0.305	0.000
H68 Eustachian salpingitis and obstruction	0.695	0.305	0.000
H67 Otitis media in diseases classified elsewhere	0.695	0.305	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.695	0.305	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.693	0.307	0.000
J41 Simple and mucopurulent chronic bronchitis	0.693	0.307	0.000
E85 Amyloidosis	0.691	0.309	0.000
Q21 Congenital malformations of cardiac septa	0.691	0.309	0.000
E04 Other non-toxic goitre	0.691	0.309	0.000
N64 Other disorders of breast	0.690	0.310	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.689	0.310	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.689	0.310	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.689	0.310	0.000
M33 Dermatopolymyositis	0.689	0.311	0.000
M30 Polyarteritis nodosa and related conditions	0.688	0.312	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.688	0.312	0.000
S31 Open wound of abdomen, lower back and pelvis	0.687	0.313	0.000
E74 Other disorders of carbohydrate metabolism	0.686	0.314	0.000
S51.9 Open wound of forearm, part unspecified	0.685	0.315	0.000
M90 Osteopathies in diseases classified elsewhere	0.684	0.316	0.000
N39.0 Urinary tract infection, site not specified	0.683	0.317	0.000
Q54 Hypospadias	0.681	0.319	0.000
M32 Systemic lupus erythematosus	0.681	0.319	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.680	0.320	0.000
Q35-Q37 Cleft lip and cleft palate	0.680	0.320	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.680	0.320	0.000
J32.0 Chronic maxillary sinusitis	0.680	0.320	0.000
N75.1 Abscess of Bartholin's gland	0.680	0.320	0.000
H66.3 Other chronic suppurative otitis media	0.679	0.321	0.000
H74 Other disorders of middle ear and mastoid	0.679	0.321	0.000
M00-M03 Infectious arthropathies	0.679	0.321	0.000
H61.1 Non-infective disorders of pinna	0.679	0.321	0.000
S42.01 Fracture of clavicle (open)	0.678	0.322	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.678	0.322	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.678	0.322	0.000
S27 Injury of other and unspecified intrathoracic organs	0.677	0.322	0.000
T70.3 Caisson disease [decompression sickness]	0.677	0.323	0.000
S43.1 Dislocation of acromioclavicular joint	0.677	0.323	0.000
T11 Other injuries of upper limb, level unspecified	0.676	0.324	0.000
E78.8 Other disorders of lipoprotein metabolism	0.676	0.324	0.000
E78.1 Pure hyperglyceridaemia	0.676	0.324	0.000
S32.0 Fracture of lumbar vertebra	0.675	0.325	0.000
S42.1 Fracture of scapula	0.675	0.325	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.675	0.325	0.000
E65-E68 Obesity and other hyperalimentation	0.674	0.326	0.000
H90-H95 Other disorders of ear	0.674	0.326	0.000
T56 Toxic effect of metals	0.673	0.327	0.000
Q23.1 Congenital insufficiency of aortic valve	0.672	0.327	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.672	0.328	0.000
H71 Cholesteatoma of middle ear	0.671	0.329	0.000
H70 Mastoiditis and related conditions	0.671	0.329	0.000
M75.8 Other shoulder lesions	0.670	0.330	0.000
K50.1 Crohn's disease of large intestine	0.669	0.331	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.669	0.331	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.668	0.332	0.000
K51.9 Ulcerative colitis, unspecified	0.668	0.332	0.000
M20.0 Deformity of finger(s)	0.668	0.332	0.000
S37 Injury of urinary and pelvic organs	0.668	0.332	0.000
E06.9 Thyroiditis, unspecified	0.668	0.332	0.000
H65.1 Other acute nonsuppurative otitis media	0.667	0.333	0.000
H65.0 Acute serous otitis media	0.667	0.333	0.000
M31 Other necrotising vasculopathies	0.666	0.334	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.665	0.335	0.000
T74 Maltreatment syndromes	0.665	0.335	0.000
T73 Effects of other deprivation	0.665	0.335	0.000
T69 Other effects of reduced temperature	0.665	0.335	0.000
T67 Effects of heat and light	0.665	0.335	0.000
T71 Asphyxiation	0.665	0.335	0.000
T66 Unspecified effects of radiation	0.665	0.335	0.000
S42.41 Fracture of lower end of humerus (open)	0.665	0.335	0.000
T01 Open wounds involving multiple body regions	0.663	0.337	0.000
M77.0 Medial epicondylitis	0.663	0.337	0.000
J37 Chronic laryngitis and laryngotracheitis	0.662	0.337	0.000
E11.4 With neurological complications	0.662	0.337	0.000
M88 Paget's disease of bone [osteitis deformans]	0.662	0.338	0.000
M45-M49 Spondylopathies	0.659	0.341	0.000
S50 Superficial injury of forearm	0.658	0.342	0.000
N73 Other female pelvic inflammatory diseases	0.656	0.343	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.656	0.344	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.656	0.344	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.656	0.344	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.656	0.344	0.000
N60.1 Diffuse cystic mastopathy	0.656	0.344	0.000
E40-E46 Malnutrition	0.655	0.345	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.654	0.345	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.654	0.346	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.654	0.346	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.654	0.346	0.000
S43.4 Sprain and strain of shoulder joint	0.654	0.346	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.654	0.346	0.000
S43.2 Dislocation of sternoclavicular joint	0.654	0.346	0.000
N76.8 Other specified inflammation of vagina and vulva	0.653	0.347	0.000
E12 Malnutrition-related diabetes mellitus	0.652	0.348	0.000
T63 Toxic effect of contact with venomous animals	0.651	0.349	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.650	0.349	0.000
N99.1 Postprocedural urethral stricture	0.650	0.349	0.000
S42.40 Fracture of lower end of humerus (closed)	0.650	0.350	0.000
N39.8 Other specified disorders of urinary system	0.650	0.350	0.000
S59 Other and unspecified injuries of forearm	0.648	0.352	0.000
E84 Cystic fibrosis	0.648	0.352	0.000
E77 Disorders of glycoprotein metabolism	0.648	0.352	0.000
E76 Disorders of glycosaminoglycan metabolism	0.648	0.352	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.648	0.352	0.000
E72 Other disorders of amino-acid metabolism	0.648	0.352	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.648	0.352	0.000
E70 Disorders of aromatic amino-acid metabolism	0.648	0.352	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.648	0.352	0.000
K90 Intestinal malabsorption	0.265	0.352	0.383
E80 Disorders of porphyrin and bilirubin metabolism	0.648	0.352	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.648	0.352	0.000
H73.1 Chronic myringitis	0.648	0.352	0.000
H73.0 Acute myringitis	0.648	0.352	0.000
M86.9 Osteomyelitis, unspecified	0.647	0.353	0.000
M71 Other bursopathies	0.647	0.353	0.000
T14 Injury of unspecified body region	0.647	0.353	0.000
T78.2 Anaphylactic shock, unspecified	0.647	0.353	0.000
E11.8 With unspecified complications	0.646	0.354	0.000
E11.7 With multiple complications	0.646	0.354	0.000
Q85 Phakomatoses, not elsewhere classified	0.645	0.354	0.000
N37 Urethral disorders in diseases classified elsewhere	0.645	0.355	0.000
N33 Bladder disorders in diseases classified elsewhere	0.645	0.355	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.645	0.355	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.643	0.356	0.000
S51.0 Open wound of elbow	0.643	0.357	0.000
E87.6 Hypokalaemia	0.643	0.357	0.000
M20.2 Hallux rigidus	0.643	0.357	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.643	0.357	0.000
E78.6 Lipoprotein deficiency	0.642	0.357	0.000
E78.3 Hyperchylomicronaemia	0.642	0.357	0.000
M24 Other specific joint derangements	0.643	0.357	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.642	0.358	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.641	0.359	0.000
J69.0 Pneumonitis due to food and vomit	0.639	0.361	0.000
E06.5 Other chronic thyroiditis	0.638	0.362	0.000
E06.4 Drug-induced thyroiditis	0.638	0.362	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.638	0.362	0.000
E06.1 Subacute thyroiditis	0.638	0.362	0.000
E06.0 Acute thyroiditis	0.638	0.362	0.000
Q26 Congenital malformations of great veins	0.637	0.362	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.637	0.362	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.637	0.362	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.637	0.363	0.000
S58 Traumatic amputation of forearm	0.634	0.365	0.000
S57 Crushing injury of forearm	0.634	0.365	0.000
S55 Injury of blood vessels at forearm level	0.634	0.365	0.000
S54 Injury of nerves at forearm level	0.634	0.365	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.634	0.365	0.000
S51.7 Multiple open wounds of forearm	0.633	0.367	0.000
E11.0 With coma	0.631	0.368	0.000
M62 Other disorders of muscle	0.631	0.369	0.000
N20-N23 Urolithiasis	0.631	0.369	0.000
Q24.8 Other specified congenital malformations of heart	0.630	0.370	0.000
H61.9 Disorder of external ear, unspecified	0.629	0.370	0.000
N39.2 Orthostatic proteinuria, unspecified	0.628	0.371	0.000
N39.1 Persistent proteinuria, unspecified	0.628	0.371	0.000
S40.0 Contusion of shoulder and upper arm	0.628	0.372	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.627	0.373	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.627	0.373	0.000
M34.0 Progressive systemic sclerosis	0.627	0.373	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.625	0.375	0.000
H66.4 Suppurative otitis media, unspecified	0.625	0.375	0.000
T65 Toxic effect of other and unspecified substances	0.625	0.375	0.000
T62 Toxic effect of other noxious substances eaten as food	0.625	0.375	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.625	0.375	0.000
T60 Toxic effect of pesticides	0.625	0.375	0.000
T57 Toxic effect of other inorganic substances	0.625	0.375	0.000
T54 Toxic effect of corrosive substances	0.625	0.375	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.625	0.375	0.000
T52 Toxic effect of organic solvents	0.625	0.375	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.625	0.375	0.000
T55 Toxic effect of soaps and detergents	0.625	0.375	0.000
M23.8 Other internal derangements of knee	0.625	0.375	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.625	0.375	0.000
N32 Other disorders of bladder	0.623	0.376	0.000
E61 Deficiency of other nutrient elements	0.623	0.377	0.000
E88 Other metabolic disorders	0.623	0.377	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.623	0.377	0.000
H72 Perforation of tympanic membrane	0.622	0.378	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.621	0.379	0.000
Q27 Other congenital malformations of peripheral vascular system	0.621	0.379	0.000
H69 Other disorders of Eustachian tube	0.621	0.379	0.000
N70 Salpingitis and oophoritis	0.621	0.379	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.620	0.380	0.000
H65.4 Other chronic nonsuppurative otitis media	0.620	0.380	0.000
M89 Other disorders of bone	0.618	0.382	0.000
J46 Status asthmaticus	0.617	0.383	0.000
M76 Enthesopathies of lower limb, excluding foot	0.615	0.385	0.000
H61.3 Acquired stenosis of external ear canal	0.615	0.385	0.000
E04.2 Non-toxic multinodular goitre	0.613	0.386	0.000
T13 Other injuries of lower limb, level unspecified	0.613	0.387	0.000
Q23.0 Congenital stenosis of aortic valve	0.612	0.388	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.610	0.390	0.000
N75.8 Other diseases of Bartholin's gland	0.610	0.390	0.000
H60.3 Other infective otitis externa	0.610	0.390	0.000
T78.9 Adverse effect, unspecified	0.609	0.391	0.000
T78.8 Other adverse effects, not elsewhere classified	0.609	0.391	0.000
Chapter XX External causes of morbidity and mortality	0.609	0.391	0.000
M23.0 Cystic meniscus	0.609	0.391	0.000
N71.0 Acute inflammatory disease of uterus	0.609	0.391	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.608	0.391	0.000
J30.1 Allergic rhinitis due to pollen	0.608	0.392	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.608	0.392	0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.608	0.392	0.000
S65 Injury of blood vessels at wrist and hand level	0.607	0.393	0.000
Q28 Other congenital malformations of circulatory system	0.606	0.393	0.000
S27.2 Traumatic heamopneumothorax	0.605	0.395	0.000
E87.2 Acidosis	0.605	0.395	0.000
N34 Urethritis and urethral syndrome	0.604	0.396	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.603	0.397	0.000
H61.8 Other specified disorders of external ear	0.602	0.398	0.000
S42.2 Fracture of upper end of humerus	0.601	0.398	0.000
N32.3 Diverticulum of bladder	0.601	0.399	0.000
H60.5 Acute otitis externa, non-infective	0.601	0.399	0.000
Q54.0 Hypospadias, balanic	0.599	0.401	0.000
S32.1 Fracture of sacrum	0.599	0.401	0.000
S69 Other and unspecified injuries of wrist and hand	0.599	0.401	0.000
N60.9 Benign mammary dysplasia, unspecified	0.598	0.402	0.000
T09 Other injuries of spine and trunk, level unspecified	0.598	0.402	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.598	0.402	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.598	0.402	0.000
T12 Fracture of lower limb, level unspecified	0.598	0.402	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.598	0.402	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.598	0.402	0.000
T10 Fracture of upper limb, level unspecified	0.598	0.402	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.598	0.402	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.598	0.402	0.000
T08 Fracture of spine, level unspecified	0.598	0.402	0.000
J70 Respiratory conditions due to other external agents	0.598	0.402	0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.598	0.402	0.000
J66 Airway disease due to specific organic dust	0.598	0.402	0.000
J63 Pneumoconiosis due to other inorganic dusts	0.598	0.402	0.000
J62 Pneumoconiosis due to dust containing silica	0.598	0.402	0.000
J65 Pneumoconiosis associated with tuberculosis	0.598	0.402	0.000
J64 Unspecified pneumoconiosis	0.598	0.402	0.000
J60 Coalworker's pneumoconiosis	0.598	0.402	0.000
Q66 Congenital deformities of feet	0.598	0.402	0.000
T02 Fractures involving multiple body regions	0.597	0.403	0.000
J30.3 Other allergic rhinitis	0.597	0.403	0.000
Q25.1 Coarctation of aorta	0.597	0.403	0.000
K90-K93 Other diseases of the digestive system	0.439	0.404	0.158
E07.8 Other specified disorders of thyroid	0.595	0.405	0.000
E07.1 Dyshormogenetic goitre	0.595	0.405	0.000
E07.0 Hypersecretion of calcitonin	0.595	0.405	0.000
M87.2 Osteonecrosis due to previous trauma	0.594	0.405	0.000
N60.2 Fibroadenosis of breast	0.594	0.406	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.594	0.406	0.000
Chapter IX Diseases of the circulatory system	0.593	0.407	0.000
T59.8 Other specified gases, fumes and vapours	0.593	0.407	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.592	0.408	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.592	0.408	0.000
E73 Lactose intolerance	0.592	0.408	0.000
E11.1 With ketoacidosis	0.592	0.408	0.000
S32.3 Fracture of ilium	0.591	0.409	0.000
S60 Superficial injury of wrist and hand	0.590	0.409	0.000
I05-I09 Chronic rheumatic heart diseases	0.590	0.410	0.000
M77.02 Medial epicondylitis (Upper arm)	0.590	0.410	0.000
N99.5 Malfunction of external stoma of urinary tract	0.588	0.412	0.000
M22.8 Other disorders of patella	0.588	0.412	0.000
K51.4 Pseudopolyposis of colon	0.588	0.412	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.587	0.413	0.000
S19 Other and unspecified injuries of neck	0.587	0.413	0.000
I08 Multiple valve diseases	0.587	0.413	0.000
N60.8 Other benign mammary dysplasias	0.587	0.413	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.586	0.414	0.000
T51 Toxic effect of alcohol	0.584	0.416	0.000
I08.0 Disorders of both mitral and aortic valves	0.584	0.416	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.583	0.417	0.000
S36.1 Injury of liver or gallbladder	0.583	0.417	0.000
E11.5 With peripheral circulatory complications	0.582	0.418	0.000
Q82 Other congenital malformations of skin	0.582	0.418	0.000
S32.5 Fracture of pubis	0.581	0.418	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.580	0.420	0.000
T05 Traumatic amputations involving multiple body regions	0.580	0.420	0.000
T04 Crushing injuries involving multiple body regions	0.580	0.420	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.580	0.420	0.000
T00 Superficial injuries involving multiple body regions	0.580	0.420	0.000
T07 Unspecified multiple injuries	0.580	0.420	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.579	0.421	0.000
S29 Other and unspecified injuries of thorax	0.578	0.422	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.577	0.422	0.000
K50.8 Other Crohn's disease	0.577	0.422	0.000
K52 Other non-infective gastro-enteritis and colitis	0.577	0.423	0.000
M43 Other deforming dorsopathies	0.577	0.423	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.576	0.423	0.000
S26 Injury of heart	0.576	0.423	0.000
S25 Injury of blood vessels of thorax	0.576	0.423	0.000
S24 Injury of nerves and spinal cord at thorax level	0.576	0.423	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.576	0.423	0.000
S21 Open wound of thorax	0.576	0.423	0.000
J30.4 Allergic rhinitis, unspecified	0.575	0.425	0.000
T18 Foreign body in alimentary tract	0.575	0.425	0.000
S67 Crushing injury of wrist and hand	0.574	0.426	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.572	0.428	0.000
S32.2 Fracture of coccyx	0.572	0.428	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.571	0.428	0.001
S64 Injury of nerves at wrist and hand level	0.569	0.431	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.568	0.431	0.000
Q84 Other congenital malformations of integument	0.568	0.431	0.000
Q83 Congenital malformations of breast	0.568	0.431	0.000
Q81 Epidermolysis bullosa	0.568	0.431	0.000
Q80 Congenital ichthyosis	0.568	0.431	0.000
K08 Other disorders of teeth and supporting structures	0.568	0.432	0.000
M35 Other systemic involvement of connective tissue	0.568	0.432	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.567	0.433	0.000
S10 Superficial injury of neck	0.566	0.434	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.565	0.435	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.564	0.436	0.000
K10 Other diseases of jaws	0.563	0.437	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.563	0.437	0.000
T68 Hypothermia	0.563	0.437	0.000
J30.2 Other seasonal allergic rhinitis	0.563	0.437	0.000
J30.0 Vasomotor rhinitis	0.563	0.437	0.000
T11.1 Open wound of upper limb, level unspecified	0.563	0.437	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.562	0.438	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.561	0.439	0.000
N64.4 Mastodynia	0.561	0.439	0.000
T79.6 Traumatic ischaemia of muscle	0.561	0.439	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.561	0.439	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.560	0.439	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations