TreeWAS – Variant ID: rs2229094

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	0.999	0.001	0.000
E11 Non-insulin-dependent diabetes mellitus	0.998	0.002	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.997	0.003	0.000
L40.5 Arthropathic psoriasis	0.996	0.004	0.000
E10 Insulin-dependent diabetes mellitus	0.995	0.005	0.000
E11.9 Without complications	0.992	0.008	0.000
E70-E90 Metabolic disorders	0.992	0.008	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.992	0.008	0.000
L40-L45 Papulosquamous disorders	0.974	0.026	0.000
E11.3 With ophthalmic complications	0.956	0.044	0.000
E20-E35 Disorders of other endocrine glands	0.936	0.064	0.000
E10.3 With ophthalmic complications	0.933	0.067	0.000
E10.4 With neurological complications	0.926	0.074	0.000
Chapter V Mental and behavioural disorders	0.921	0.079	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.918	0.082	0.000
H71 Cholesteatoma of middle ear	0.917	0.083	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.916	0.084	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.913	0.087	0.000
H65-H75 Diseases of middle ear and mastoid	0.913	0.087	0.000
F30-F39 Mood [affective] disorders	0.912	0.088	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.907	0.093	0.000
E10.5 With peripheral circulatory complications	0.903	0.097	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.902	0.098	0.000
# Top node	0.897	0.103	0.000
E21.3 Hyperparathyroidism, unspecified	0.894	0.106	0.000
Chapter VIII Diseases of the ear and mastoid process	0.894	0.106	0.000
L05 Pilonidal cyst	0.887	0.113	0.000
F30 Manic episode	0.886	0.114	0.000
L40.0 Psoriasis vulgaris	0.881	0.119	0.000
L43 Lichen planus	0.876	0.124	0.000
F43 Reaction to severe stress, and adjustment disorders	0.876	0.124	0.000
F33 Recurrent depressive disorder	0.876	0.124	0.000
F41 Other anxiety disorders	0.876	0.124	0.000
L05.0 Pilonidal cyst with abscess	0.875	0.125	0.000
L03 Cellulitis	0.872	0.128	0.000
F60-F69 Disorders of adult personality and behaviour	0.869	0.131	0.000
E11.0 With coma	0.862	0.138	0.000
L03.3 Cellulitis of trunk	0.861	0.139	0.000
F30.0 Hypomania	0.847	0.153	0.000
F33.9 Recurrent depressive disorder, unspecified	0.846	0.154	0.000
F44 Dissociative [conversion] disorders	0.834	0.166	0.000
F60 Specific personality disorders	0.833	0.167	0.000
H73 Other disorders of tympanic membrane	0.832	0.168	0.000
E11.4 With neurological complications	0.826	0.174	0.000
F43.0 Acute stress reaction	0.823	0.177	0.000
H72 Perforation of tympanic membrane	0.817	0.183	0.000
E11.6 With other specified complications	0.814	0.186	0.000
E50-E64 Other nutritional deficiencies	0.807	0.193	0.000
E10.8 With unspecified complications	0.805	0.195	0.000
L43.8 Other lichen planus	0.801	0.199	0.000
E89.1 Postprocedural hypoinsulinaemia	0.800	0.200	0.000
F43.2 Adjustment disorders	0.789	0.211	0.000
H73.8 Other specified disorders of tympanic membrane	0.781	0.219	0.000
E28 Ovarian dysfunction	0.780	0.220	0.000
F60.3 Emotionally unstable personality disorder	0.779	0.221	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.775	0.225	0.000
E10.1 With ketoacidosis	0.775	0.225	0.000
L04 Acute lymphadenitis	0.774	0.226	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.774	0.226	0.000
E26 Hyperaldosteronism	0.773	0.227	0.000
H66 Suppurative and unspecified otitis media	0.772	0.228	0.000
F30.9 Manic episode, unspecified	0.769	0.231	0.000
E79 Disorders of purine and pyrimidine metabolism	0.768	0.232	0.000
F60.9 Personality disorder, unspecified	0.768	0.232	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.767	0.233	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.766	0.234	0.000
E85 Amyloidosis	0.765	0.235	0.000
T42.4 Benzodiazepines	0.765	0.235	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.765	0.235	0.000
L42 Pityriasis rosea	0.764	0.236	0.000
E89.3 Postprocedural hypopituitarism	0.763	0.237	0.000
E10.6 With other specified complications	0.758	0.242	0.000
F32 Depressive episode	0.758	0.242	0.000
E61 Deficiency of other nutrient elements	0.758	0.242	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.754	0.246	0.000
E89.2 Postprocedural hypoparathyroidism	0.753	0.247	0.000
F41.1 Generalised anxiety disorder	0.753	0.247	0.000
L03.9 Cellulitis, unspecified	0.752	0.248	0.000
L40.8 Other psoriasis	0.751	0.249	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.748	0.252	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.747	0.253	0.000
F41.9 Anxiety disorder, unspecified	0.745	0.255	0.000
F41.2 Mixed anxiety and depressive disorder	0.742	0.258	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.742	0.258	0.000
E78.3 Hyperchylomicronaemia	0.741	0.259	0.000
H72.0 Central perforation of tympanic membrane	0.739	0.261	0.000
E74 Other disorders of carbohydrate metabolism	0.737	0.263	0.000
E10.9 Without complications	0.729	0.271	0.000
E61.1 Iron deficiency	0.728	0.272	0.000
E78.6 Lipoprotein deficiency	0.727	0.273	0.000
L40.1 Generalised pustular psoriasis	0.727	0.273	0.000
E65-E68 Obesity and other hyperalimentation	0.725	0.275	0.000
E10.0 With coma	0.718	0.282	0.000
H66.3 Other chronic suppurative otitis media	0.718	0.282	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.716	0.284	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.716	0.284	0.000
E11.7 With multiple complications	0.716	0.284	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.715	0.285	0.000
E10.7 With multiple complications	0.713	0.286	0.000
H72.8 Other perforations of tympanic membrane	0.712	0.288	0.000
E77 Disorders of glycoprotein metabolism	0.711	0.289	0.000
E76 Disorders of glycosaminoglycan metabolism	0.711	0.289	0.000
E72 Other disorders of amino-acid metabolism	0.711	0.289	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.711	0.289	0.000
E70 Disorders of aromatic amino-acid metabolism	0.711	0.289	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.711	0.289	0.000
E88 Other metabolic disorders	0.709	0.291	0.000
F32.9 Depressive episode, unspecified	0.709	0.291	0.000
F45 Somatoform disorders	0.708	0.292	0.000
F80-F89 Disorders of psychological development	0.704	0.296	0.000
F48 Other neurotic disorders	0.703	0.296	0.000
E28.2 Polycystic ovarian syndrome	0.702	0.298	0.000
L40.3 Pustulosis palmaris et plantaris	0.702	0.298	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.701	0.299	0.000
E23 Hypofunction and other disorders of pituitary gland	0.699	0.301	0.000
E89.4 Postprocedural ovarian failure	0.699	0.301	0.000
L44 Other papulosquamous disorders	0.699	0.301	0.000
L41 Parapsoriasis	0.699	0.301	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.699	0.301	0.000
E84 Cystic fibrosis	0.699	0.301	0.000
E21.2 Other hyperparathyroidism	0.697	0.303	0.000
E21.4 Other specified disorders of parathyroid gland	0.697	0.303	0.000
E14 Unspecified diabetes mellitus	0.696	0.304	0.000
E11.2 With renal complications	0.693	0.307	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.689	0.311	0.000
E13 Other specified diabetes mellitus	0.688	0.312	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.688	0.312	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.687	0.313	0.000
L03.8 Cellulitis of other sites	0.687	0.313	0.000
H65 Nonsuppurative otitis media	0.682	0.318	0.000
E20 Hypoparathyroidism	0.681	0.319	0.000
F39 Unspecified mood [affective] disorder	0.679	0.321	0.000
F44.5 Dissociative convulsions	0.677	0.323	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.677	0.323	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.675	0.325	0.000
E40-E46 Malnutrition	0.674	0.326	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.672	0.328	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.672	0.328	0.000
T91 Sequelae of injuries of neck and trunk	0.672	0.328	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.671	0.329	0.000
E32 Diseases of thymus	0.671	0.329	0.000
E31 Polyglandular dysfunction	0.671	0.329	0.000
E30 Disorders of puberty, not elsewhere classified	0.671	0.329	0.000
T36 Poisoning by systemic antibiotics	0.670	0.330	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.669	0.331	0.000
T50.8 Diagnostic agents	0.666	0.334	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.666	0.334	0.000
F41.3 Other mixed anxiety disorders	0.663	0.337	0.000
L05.9 Pilonidal cyst without abscess	0.662	0.338	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.661	0.339	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.660	0.340	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.660	0.340	0.000
E25 Adrenogenital disorders	0.659	0.341	0.000
F60.5 Anankastic personality disorder	0.659	0.341	0.000
F42 Obsessive-compulsive disorder	0.657	0.343	0.000
T91.1 Sequelae of fracture of spine	0.655	0.345	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.655	0.345	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.655	0.345	0.000
E89.5 Postprocedural testicular hypofunction	0.655	0.345	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.655	0.345	0.000
H68 Eustachian salpingitis and obstruction	0.655	0.345	0.000
H67 Otitis media in diseases classified elsewhere	0.655	0.345	0.000
E65 Localised adiposity	0.654	0.345	0.000
F38 Other mood [affective] disorders	0.654	0.346	0.000
E51 Thiamine deficiency	0.652	0.348	0.000
H72.1 Attic perforation of tympanic membrane	0.650	0.350	0.000
E24 Cushing's syndrome	0.648	0.352	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.648	0.352	0.000
F44.0 Dissociative amnesia	0.647	0.353	0.000
L00 Staphylococcal scalded skin syndrome	0.647	0.353	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.646	0.354	0.000
L43.9 Lichen planus, unspecified	0.644	0.356	0.000
F99-F99 Unspecified mental disorder	0.643	0.356	0.000
F70-F79 Mental retardation	0.643	0.356	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.643	0.357	0.000
L03.0 Cellulitis of finger and toe	0.642	0.358	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.640	0.360	0.000
E78.4 Other hyperlipidaemia	0.638	0.362	0.000
T91.3 Sequelae of injury of spinal cord	0.636	0.364	0.000
F30.8 Other manic episodes	0.635	0.365	0.000
F30.1 Mania without psychotic symptoms	0.635	0.365	0.000
L43.3 Subacute (active) lichen planus	0.628	0.372	0.000
L43.2 Lichenoid drug reaction	0.628	0.372	0.000
L43.1 Bullous lichen planus	0.628	0.372	0.000
L43.0 Hypertrophic lichen planus	0.628	0.372	0.000
Q80-Q89 Other congenital malformations	0.628	0.372	0.000
F43.8 Other reactions to severe stress	0.628	0.372	0.000
F33.8 Other recurrent depressive disorders	0.628	0.372	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.628	0.372	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.627	0.373	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.626	0.374	0.000
F30.2 Mania with psychotic symptoms	0.624	0.376	0.000
F68 Other disorders of adult personality and behaviour	0.623	0.377	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.623	0.377	0.000
F65 Disorders of sexual preference	0.623	0.377	0.000
F63 Habit and impulse disorders	0.623	0.377	0.000
F61 Mixed and other personality disorders	0.623	0.377	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.623	0.377	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.622	0.378	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.620	0.380	0.000
E26.0 Primary hyperaldosteronism	0.620	0.380	0.000
L04.9 Acute lymphadenitis, unspecified	0.620	0.380	0.000
F84 Pervasive developmental disorders	0.618	0.382	0.000
S90-S99 Injuries to the ankle and foot	0.618	0.382	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.615	0.385	0.000
F45.8 Other somatoform disorders	0.615	0.385	0.000
L04.2 Acute lymphadenitis of upper limb	0.611	0.389	0.000
E78.1 Pure hyperglyceridaemia	0.609	0.391	0.000
F32.8 Other depressive episodes	0.609	0.391	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.608	0.392	0.000
E34 Other endocrine disorders	0.607	0.393	0.000
L01 Impetigo	0.606	0.394	0.000
E11.1 With ketoacidosis	0.606	0.394	0.000
E26.9 Hyperaldosteronism, unspecified	0.605	0.395	0.000
E78.8 Other disorders of lipoprotein metabolism	0.603	0.397	0.000
E73 Lactose intolerance	0.602	0.398	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.600	0.400	0.000
F34 Persistent mood [affective] disorders	0.600	0.400	0.000
E10.2 With renal complications	0.599	0.401	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.599	0.401	0.000
L04.1 Acute lymphadenitis of trunk	0.599	0.401	0.000
F44.8 Other dissociative [conversion] disorders	0.598	0.402	0.000
F44.7 Mixed dissociative [conversion] disorders	0.598	0.402	0.000
F44.6 Dissociative anaesthesia and sensory loss	0.598	0.402	0.000
F44.3 Trance and possession disorders	0.598	0.402	0.000
F44.2 Dissociative stupor	0.598	0.402	0.000
F44.1 Dissociative fugue	0.598	0.402	0.000
F60.8 Other specific personality disorders	0.597	0.403	0.000
F60.4 Histrionic personality disorder	0.597	0.403	0.000
F60.2 Dissocial personality disorder	0.597	0.403	0.000
F60.1 Schizoid personality disorder	0.597	0.403	0.000
H73.1 Chronic myringitis	0.597	0.403	0.000
H73.0 Acute myringitis	0.597	0.403	0.000
F64 Gender identity disorders	0.596	0.404	0.000
T36.0 Penicillins	0.595	0.405	0.000
E14.4 With neurological complications	0.595	0.405	0.000
E85.9 Amyloidosis, unspecified	0.594	0.406	0.000
Q25 Congenital malformations of great arteries	0.593	0.407	0.000
F69 Unspecified disorder of adult personality and behaviour	0.592	0.408	0.000
E29 Testicular dysfunction	0.588	0.412	0.000
E56 Other vitamin deficiencies	0.588	0.412	0.000
H65.3 Chronic mucoid otitis media	0.586	0.414	0.000
T42.0 Hydantoin derivatives	0.580	0.420	0.000
E23.6 Other disorders of pituitary gland	0.580	0.420	0.000
H70 Mastoiditis and related conditions	0.579	0.421	0.000
T42.1 Iminostilbenes	0.579	0.421	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.578	0.422	0.000
E63 Other nutritional deficiencies	0.578	0.422	0.000
E50 Vitamin A deficiency	0.578	0.422	0.000
E60 Dietary zinc deficiency	0.578	0.422	0.000
E59 Dietary selenium deficiency	0.578	0.422	0.000
E58 Dietary calcium deficiency	0.578	0.422	0.000
E54 Ascorbic acid deficiency	0.578	0.422	0.000
E52 Niacin deficiency [pellagra]	0.578	0.422	0.000
T88.4 Failed or difficult intubation	0.578	0.422	0.000
F43.9 Reaction to severe stress, unspecified	0.577	0.423	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.577	0.423	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.576	0.424	0.000
H74 Other disorders of middle ear and mastoid	0.575	0.425	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.574	0.426	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.574	0.426	0.000
T66-T78 Other and unspecified effects of external causes	0.572	0.428	0.000
F60.0 Paranoid personality disorder	0.571	0.429	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.569	0.431	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.568	0.432	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.567	0.433	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.566	0.434	0.000
E14.8 With unspecified complications	0.566	0.434	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.565	0.435	0.000
Q21 Congenital malformations of cardiac septa	0.565	0.435	0.000
H66.4 Suppurative otitis media, unspecified	0.562	0.438	0.000
E85.3 Secondary systemic amyloidosis	0.561	0.439	0.000
E28.9 Ovarian dysfunction, unspecified	0.559	0.441	0.000
E28.8 Other ovarian dysfunction	0.559	0.441	0.000
E28.1 Androgen excess	0.559	0.441	0.000
E28.0 Oestrogen excess	0.559	0.441	0.000
F48.9 Neurotic disorder, unspecified	0.559	0.441	0.000
F84.5 Asperger's syndrome	0.557	0.443	0.000
S40-S49 Injuries to the shoulder and upper arm	0.557	0.443	0.000
T50.4 Drugs affecting uric acid metabolism	0.557	0.443	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.556	0.444	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.556	0.444	0.000
E11.5 With peripheral circulatory complications	0.555	0.445	0.000
L04.8 Acute lymphadenitis of other sites	0.555	0.445	0.000
L04.3 Acute lymphadenitis of lower limb	0.555	0.445	0.000
L04.0 Acute lymphadenitis of face, head and neck	0.555	0.445	0.000
E26.8 Other hyperaldosteronism	0.554	0.446	0.000
E26.1 Secondary hyperaldosteronism	0.554	0.446	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.554	0.446	0.000
Q85 Phakomatoses, not elsewhere classified	0.552	0.448	0.000
H72.2 Other marginal perforations of tympanic membrane	0.551	0.449	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.551	0.449	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.551	0.449	0.000
E79.1 Lesch-Nyhan syndrome	0.551	0.449	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.550	0.450	0.000
T42.3 Barbiturates	0.550	0.450	0.000
T42.2 Succinimides and oxazolidinediones	0.550	0.450	0.000
E23.7 Disorder of pituitary gland, unspecified	0.549	0.450	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.549	0.451	0.000
T50.7 Analeptics and opioid receptor antagonists	0.549	0.451	0.000
T50.5 Appetite depressants	0.549	0.451	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.549	0.451	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.549	0.451	0.000
T50.1 Loop [high-ceiling] diuretics	0.549	0.451	0.000
T50.0 Mineralocorticoids and their antagonists	0.549	0.451	0.000
E80.6 Other disorders of bilirubin metabolism	0.549	0.451	0.000
E85.8 Other amyloidosis	0.549	0.451	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.549	0.451	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.549	0.451	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.549	0.451	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.549	0.451	0.000
E85.4 Organ-limited amyloidosis	0.549	0.451	0.000
F44.4 Dissociative motor disorders	0.546	0.454	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.545	0.455	0.000
E88.8 Other specified metabolic disorders	0.544	0.456	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.544	0.456	0.000
E61.9 Deficiency of nutrient element, unspecified	0.543	0.457	0.000
E61.8 Deficiency of other specified nutrient elements	0.543	0.457	0.000
E61.7 Deficiency of multiple nutrient elements	0.543	0.457	0.000
E61.6 Vanadium deficiency	0.543	0.457	0.000
E61.5 Molybdenum deficiency	0.543	0.457	0.000
E61.4 Chromium deficiency	0.543	0.457	0.000
E61.3 Manganese deficiency	0.543	0.457	0.000
E61.0 Copper deficiency	0.543	0.457	0.000
H65.2 Chronic serous otitis media	0.543	0.457	0.000
F51 Nonorganic sleep disorders	0.542	0.458	0.000
F43.1 Posttraumatic stress disorder	0.542	0.458	0.000
E51.2 Wernicke's encephalopathy	0.541	0.459	0.000
F41.8 Other specified anxiety disorders	0.541	0.459	0.000
T33-T35 Frostbite	0.541	0.459	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.541	0.459	0.000
T00-T07 Injuries involving multiple body regions	0.540	0.459	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.540	0.460	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.539	0.461	0.000
Q35-Q37 Cleft lip and cleft palate	0.539	0.461	0.000
T95 Sequelae of burns, corrosions and frostbite	0.538	0.462	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.537	0.463	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.536	0.464	0.000
Q25.1 Coarctation of aorta	0.536	0.464	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.534	0.466	0.000
Q00-Q07 Congenital malformations of the nervous system	0.532	0.468	0.000
T87 Complications peculiar to reattachment and amputation	0.530	0.470	0.000
S97 Crushing injury of ankle and foot	0.530	0.470	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.528	0.472	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.528	0.472	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.528	0.472	0.000
E74.2 Disorders of galactose metabolism	0.528	0.472	0.000
E74.1 Disorders of fructose metabolism	0.528	0.472	0.000
E74.0 Glycogen storage disease	0.528	0.472	0.000
F62.9 Enduring personality change, unspecified	0.526	0.474	0.000
H65.0 Acute serous otitis media	0.525	0.474	0.000
Q83 Congenital malformations of breast	0.524	0.476	0.000
E14.5 With peripheral circulatory complications	0.523	0.477	0.000
E13.3 With ophthalmic complications	0.522	0.478	0.000
E67 Other hyperalimentation	0.520	0.480	0.000
E68 Sequelae of hyperalimentation	0.520	0.480	0.000
F50 Eating disorders	0.518	0.482	0.000
F45.4 Persistent somatoform pain disorder	0.518	0.482	0.000
H60-H62 Diseases of external ear	0.516	0.483	0.000
F45.2 Hypochondriacal disorder	0.516	0.484	0.000
E14.6 With other specified complications	0.516	0.484	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.513	0.487	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.512	0.487	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.512	0.488	0.000
E27 Other disorders of adrenal gland	0.508	0.489	0.004
H74.8 Other specified disorders of middle ear and mastoid	0.511	0.489	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.510	0.490	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.510	0.490	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.510	0.490	0.000
E70.3 Albinism	0.510	0.490	0.000
E70.2 Disorders of tyrosine metabolism	0.510	0.490	0.000
E70.1 Other hyperphenylalaninaemias	0.510	0.490	0.000
E70.0 Classical phenylketonuria	0.510	0.490	0.000
E71.3 Disorders of fatty-acid metabolism	0.510	0.490	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.510	0.490	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.510	0.490	0.000
E71.0 Maple-syrup-urine disease	0.510	0.490	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.510	0.490	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.510	0.490	0.000
E72.5 Disorders of glycine metabolism	0.510	0.490	0.000
E72.4 Disorders of ornithine metabolism	0.510	0.490	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.510	0.490	0.000
E72.2 Disorders of urea cycle metabolism	0.510	0.490	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.510	0.490	0.000
E72.0 Disorders of amino-acid transport	0.510	0.490	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.510	0.490	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.510	0.490	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.510	0.490	0.000
E76.2 Other mucopolysaccharidoses	0.510	0.490	0.000
E76.1 Mucopolysaccharidosis, type II	0.510	0.490	0.000
E76.0 Mucopolysaccharidosis, type I	0.510	0.490	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.510	0.490	0.000
E77.8 Other disorders of glycoprotein metabolism	0.510	0.490	0.000
E77.1 Defects in glycoprotein degradation	0.510	0.490	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.510	0.490	0.000
L03.2 Cellulitis of face	0.510	0.490	0.000
E88.9 Metabolic disorder, unspecified	0.508	0.492	0.000
F45.1 Undifferentiated somatoform disorder	0.508	0.492	0.000
T88.9 Complication of surgical and medical care, unspecified	0.507	0.492	0.000
H65.1 Other acute nonsuppurative otitis media	0.505	0.495	0.000
F89 Unspecified disorder of psychological development	0.505	0.495	0.000
F88 Other disorders of psychological development	0.505	0.495	0.000
F83 Mixed specific developmental disorders	0.505	0.495	0.000
F82 Specific developmental disorder of motor function	0.505	0.495	0.000
F48.8 Other specified neurotic disorders	0.504	0.495	0.000
F48.1 Depersonalisation-derealisation syndrome	0.504	0.495	0.000
F01 Vascular dementia	0.504	0.496	0.000
H66.0 Acute suppurative otitis media	0.503	0.497	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.503	0.497	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.503	0.497	0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.503	0.497	0.000
F55 Abuse of non-dependence-producing substances	0.503	0.497	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.503	0.497	0.000
E80.2 Other porphyria	0.502	0.498	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.502	0.498	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.501	0.499	0.000
E23.1 Drug-induced hypopituitarism	0.501	0.499	0.000
F45.9 Somatoform disorder, unspecified	0.501	0.499	0.000
L41.9 Parapsoriasis, unspecified	0.501	0.499	0.000
L41.8 Other parapsoriasis	0.501	0.499	0.000
L41.5 Retiform parapsoriasis	0.501	0.499	0.000
L41.4 Large plaque parapsoriasis	0.501	0.499	0.000
L41.3 Small plaque parapsoriasis	0.501	0.499	0.000
L41.2 Lymphomatoid papulosis	0.501	0.499	0.000
L41.1 Pityriasis lichenoides chronica	0.501	0.499	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.501	0.499	0.000
L44.9 Papulosquamous disorder, unspecified	0.501	0.499	0.000
L44.8 Other specified papulosquamous disorders	0.501	0.499	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.501	0.499	0.000
L44.3 Lichen ruber moniliformis	0.501	0.499	0.000
L44.2 Lichen striatus	0.501	0.499	0.000
L44.1 Lichen nitidus	0.501	0.499	0.000
L44.0 Pityriasis rubra pilaris	0.501	0.499	0.000
E84.8 Cystic fibrosis with other manifestations	0.501	0.499	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.501	0.499	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.501	0.499	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.501	0.499	0.000
E61.2 Magnesium deficiency	0.500	0.500	0.000
E14.7 With multiple complications	0.499	0.501	0.000
E14.2 Withrenal complications	0.499	0.501	0.000
E14.0 With coma	0.499	0.501	0.000
E20.9 Hypoparathyroidism, unspecified	0.499	0.501	0.000
T43.6 Psychostimulants with abuse potential	0.498	0.502	0.000
T78 Adverse effects, not elsewhere classified	0.497	0.503	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.497	0.503	0.000
E75.6 Lipid storage disorder, unspecified	0.494	0.506	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.494	0.506	0.000
E75.3 Sphingolipidosis, unspecified	0.494	0.506	0.000
E75.2 Other sphingolipidosis	0.494	0.506	0.000
E75.1 Other gangliosidosis	0.494	0.506	0.000
E75.0 GM2 gangliosidosis	0.494	0.506	0.000
E24.0 Pituitary-dependent Cushing's disease	0.494	0.506	0.000
E13.8 With unspecified complications	0.493	0.506	0.000
E13.7 With multiple complications	0.493	0.506	0.000
E13.6 With other specified complications	0.493	0.506	0.000
E13.5 With peripheral circulatory complications	0.493	0.506	0.000
E13.4 With neurological complications	0.493	0.506	0.000
E13.2 With renal complications	0.493	0.506	0.000
E13.1 With ketoacidosis	0.493	0.506	0.000
E13.0 With coma	0.493	0.506	0.000
Q23 Congenital malformations of aortic and mitral valves	0.493	0.507	0.000
F48.0 Neurasthenia	0.492	0.508	0.000
T88.2 Shock due to anaesthesia	0.492	0.508	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.491	0.509	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.491	0.509	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.490	0.509	0.000
E11.8 With unspecified complications	0.490	0.510	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.489	0.511	0.000
E20.8 Other hypoparathyroidism	0.488	0.511	0.000
E20.1 Pseudohypoparathyroidism	0.488	0.511	0.000
E20.0 Idiopathic hypoparathyroidism	0.488	0.511	0.000
E84.9 Cystic fibrosis, unspecified	0.488	0.512	0.000
T47.0 Histamine H(2)-receptor antagonists	0.488	0.512	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.487	0.512	0.000
F60.6 Anxious [avoidant] personality disorder	0.487	0.513	0.000
E80.1 Porphyria cutanea tarda	0.487	0.513	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.487	0.513	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.485	0.515	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.485	0.515	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.485	0.515	0.000
T88.0 Infection following immunisation	0.485	0.515	0.000
T79-T79 Certain early complications of trauma	0.484	0.516	0.000
F60.7 Dependent personality disorder	0.483	0.517	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.483	0.517	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations