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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2233969
log Bayes Factor = 31.0453
Chromosome 6   position 31,080,432  (GRCh37) Explore rs2233969 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.004 0.996
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.007 0.993
E16 Other disorders of pancreatic internal secretion
0.000 0.009 0.991
M45.X9 Ankylosing spondylitis (Site unspecified)
0.990 0.010 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.010 0.990
E00-E07 Disorders of thyroid gland
0.001 0.011 0.988
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.015 0.985
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.017 0.983
E10.1 With ketoacidosis
0.000 0.021 0.979
E10.9 Without complications
0.000 0.023 0.977
E03.9 Hypothyroidism, unspecified
0.975 0.025 0.000
G35 Multiple sclerosis
0.000 0.048 0.952
E10.2 With renal complications
0.000 0.050 0.950
L40.9 Psoriasis, unspecified
0.000 0.054 0.946
L40 Psoriasis
0.000 0.057 0.943
L40.5 Arthropathic psoriasis
0.000 0.061 0.939
E06 Thyroiditis
0.000 0.088 0.912
M45 Ankylosing spondylitis
0.883 0.117 0.000
L40.0 Psoriasis vulgaris
0.000 0.142 0.858
E06.9 Thyroiditis, unspecified
0.000 0.181 0.819
E65-E68 Obesity and other hyperalimentation
0.000 0.183 0.817
E03 Other hypothyroidism
0.631 0.184 0.184
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.795 0.205 0.000
E10.5 With peripheral circulatory complications
0.000 0.206 0.794
E50-E64 Other nutritional deficiencies
0.000 0.207 0.793
E10.8 With unspecified complications
0.000 0.213 0.787
E05.8 Other thyrotoxicosis
0.000 0.218 0.782
E10.4 With neurological complications
0.000 0.221 0.779
E16.1 Other hypoglycaemia
0.000 0.221 0.779
E11 Non-insulin-dependent diabetes mellitus
0.000 0.223 0.777
M45.X2 Ankylosing spondylitis (Cervical region)
0.766 0.234 0.000
E06.3 Autoimmune thyroiditis
0.000 0.240 0.760
E13 Other specified diabetes mellitus
0.000 0.245 0.755
M45.X6 Ankylosing spondylitis (Lumbar region)
0.737 0.263 0.000
E10.6 With other specified complications
0.000 0.268 0.732
E55 Vitamin D deficiency
0.000 0.275 0.725
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.276 0.724
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.288 0.712
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.289 0.711
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.289 0.711
E16.4 Abnormal secretion of gastrin
0.000 0.289 0.711
E16.3 Increased secretion of glucagon
0.000 0.289 0.711
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.001 0.291 0.708
E00 Congenital iodine-deficiency syndrome
0.001 0.291 0.708
E02 Subclinical iodine-deficiency hypothyroidism
0.001 0.291 0.708
E05.5 Thyroid crisis or storm
0.000 0.294 0.706
E05.4 Thyrotoxicosis factitia
0.000 0.294 0.706
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.294 0.706
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.294 0.706
E10.0 With coma
0.000 0.295 0.705
E11.3 With ophthalmic complications
0.000 0.313 0.687
L40.1 Generalised pustular psoriasis
0.000 0.321 0.679
E55.9 Vitamin D deficiency, unspecified
0.000 0.323 0.677
L40.4 Guttate psoriasis
0.000 0.324 0.676
L40.3 Pustulosis palmaris et plantaris
0.000 0.324 0.676
L40.2 Acrodermatitis continua
0.000 0.324 0.676
E65 Localised adiposity
0.000 0.334 0.666
E11.6 With other specified complications
0.000 0.344 0.656
E06.5 Other chronic thyroiditis
0.000 0.346 0.654
E06.4 Drug-induced thyroiditis
0.000 0.346 0.654
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.346 0.654
E06.1 Subacute thyroiditis
0.000 0.346 0.654
E06.0 Acute thyroiditis
0.000 0.346 0.654
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.360 0.640
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.633 0.367 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.633 0.367 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.633 0.367 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.633 0.367 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.633 0.367 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.633 0.367 0.000
E40-E46 Malnutrition
0.000 0.374 0.626
E66 Obesity
0.000 0.380 0.620
E11.4 With neurological complications
0.000 0.381 0.619
E11.2 With renal complications
0.000 0.389 0.611
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.500 0.394 0.106
E11.8 With unspecified complications
0.000 0.401 0.599
E67 Other hyperalimentation
0.000 0.414 0.586
E68 Sequelae of hyperalimentation
0.000 0.414 0.586
E03.5 Myxoedema coma
0.453 0.415 0.132
E03.4 Atrophy of thyroid (acquired)
0.453 0.415 0.132
E03.3 Postinfectious hypothyroidism
0.453 0.415 0.132
E03.1 Congenital hypothyroidism without goitre
0.453 0.415 0.132
E03.0 Congenital hypothyroidism with diffuse goitre
0.453 0.415 0.132
E13.9 Without complications
0.000 0.419 0.581
L40.8 Other psoriasis
0.000 0.420 0.580
E03.8 Other specified hypothyroidism
0.474 0.420 0.106
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.431 0.569
E63 Other nutritional deficiencies
0.000 0.431 0.569
E51 Thiamine deficiency
0.000 0.431 0.569
E50 Vitamin A deficiency
0.000 0.431 0.569
E60 Dietary zinc deficiency
0.000 0.431 0.569
E59 Dietary selenium deficiency
0.000 0.431 0.569
E58 Dietary calcium deficiency
0.000 0.431 0.569
E54 Ascorbic acid deficiency
0.000 0.431 0.569
E52 Niacin deficiency [pellagra]
0.000 0.431 0.569
E66.8 Other obesity
0.000 0.442 0.558
E11.7 With multiple complications
0.000 0.443 0.557
K90 Intestinal malabsorption
0.000 0.454 0.546
E13.8 With unspecified complications
0.000 0.459 0.541
E13.7 With multiple complications
0.000 0.459 0.541
E13.6 With other specified complications
0.000 0.459 0.541
E13.5 With peripheral circulatory complications
0.000 0.459 0.541
E13.4 With neurological complications
0.000 0.459 0.541
E13.3 With ophthalmic complications
0.000 0.459 0.541
E13.2 With renal complications
0.000 0.459 0.541
E13.1 With ketoacidosis
0.000 0.459 0.541
E13.0 With coma
0.000 0.459 0.541
E05.9 Thyrotoxicosis, unspecified
0.000 0.462 0.538
E61 Deficiency of other nutrient elements
0.000 0.469 0.531
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.479 0.521
E55.0 Rickets, active
0.000 0.480 0.520
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.001 0.492 0.508
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.001 0.492 0.508
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.001 0.492 0.508
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.001 0.492 0.508
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.001 0.492 0.508
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.001 0.492 0.508
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.001 0.492 0.508
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.001 0.492 0.508
E11.1 With ketoacidosis
0.000 0.500 0.500
E56 Other vitamin deficiencies
0.000 0.501 0.499
E11.5 With peripheral circulatory complications
0.000 0.509 0.491
E11.0 With coma
0.000 0.517 0.483
E66.0 Obesity due to excess calories
0.000 0.522 0.478
E53 Deficiency of other B group vitamins
0.000 0.522 0.478
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.522 0.478
E07 Other disorders of thyroid
0.001 0.530 0.468
E70-E90 Metabolic disorders
0.000 0.531 0.469
E83.1 Disorders of iron metabolism
0.000 0.538 0.462
L40-L45 Papulosquamous disorders
0.000 0.539 0.461
E83 Disorders of mineral metabolism
0.000 0.540 0.460
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.551 0.449
E45 Retarded development following protein-energy malnutrition
0.000 0.551 0.449
E43 Unspecified severe protein-energy malnutrition
0.000 0.551 0.449
E42 Marasmic kwashiorkor
0.000 0.551 0.449
E41 Nutritional marasmus
0.000 0.551 0.449
E40 Kwashiorkor
0.000 0.551 0.449
E66.1 Drug-induced obesity
0.000 0.555 0.445
G37 Other demyelinating diseases of central nervous system
0.000 0.559 0.441
E14 Unspecified diabetes mellitus
0.000 0.567 0.433
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.568 0.432
E67.8 Other specified hyperalimentation
0.000 0.580 0.420
E67.3 Hypervitaminosis D
0.000 0.580 0.420
E67.2 Megavitamin-B6 syndrome
0.000 0.580 0.420
E67.1 Hypercarotenaemia
0.000 0.580 0.420
E67.0 Hypervitaminosis A
0.000 0.580 0.420
K90.8 Other intestinal malabsorption
0.000 0.591 0.409
E50.9 Vitamin A deficiency, unspecified
0.000 0.592 0.408
E50.8 Other manifestations of vitamin A deficiency
0.000 0.592 0.408
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.592 0.408
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.592 0.408
E50.5 Vitamin A deficiency with night blindness
0.000 0.592 0.408
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.592 0.408
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.592 0.408
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.592 0.408
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.592 0.408
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.592 0.408
E51.9 Thiamine deficiency, unspecified
0.000 0.592 0.408
E51.8 Other manifestations of thiamine deficiency
0.000 0.592 0.408
E51.2 Wernicke's encephalopathy
0.000 0.592 0.408
E51.1 Beriberi
0.000 0.592 0.408
E63.9 Nutritional deficiency, unspecified
0.000 0.592 0.408
E63.8 Other specified nutritional deficiencies
0.000 0.592 0.408
E63.1 Imbalance of constituents of food intake
0.000 0.592 0.408
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.592 0.408
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.592 0.408
E64.8 Sequelae of other nutritional deficiencies
0.000 0.592 0.408
E64.3 Sequelae of rickets
0.000 0.592 0.408
E64.2 Sequelae of vitamin C deficiency
0.000 0.592 0.408
E64.1 Sequelae of vitamin A deficiency
0.000 0.592 0.408
E64.0 Sequelae of protein-energy malnutrition
0.000 0.592 0.408
E61.2 Magnesium deficiency
0.000 0.602 0.398
E85 Amyloidosis
0.000 0.605 0.395
K90.9 Intestinal malabsorption, unspecified
0.000 0.606 0.394
K90.3 Pancreatic steatorrhoea
0.000 0.608 0.392
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.608 0.392
K90.1 Tropical sprue
0.000 0.608 0.392
E61.9 Deficiency of nutrient element, unspecified
0.000 0.619 0.381
E61.8 Deficiency of other specified nutrient elements
0.000 0.619 0.381
E61.7 Deficiency of multiple nutrient elements
0.000 0.619 0.381
E61.6 Vanadium deficiency
0.000 0.619 0.381
E61.5 Molybdenum deficiency
0.000 0.619 0.381
E61.4 Chromium deficiency
0.000 0.619 0.381
E61.3 Manganese deficiency
0.000 0.619 0.381
E61.0 Copper deficiency
0.000 0.619 0.381
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.622 0.378
E53.9 Vitamin B deficiency, unspecified
0.000 0.624 0.376
E83.5 Disorders of calcium metabolism
0.000 0.629 0.371
L42 Pityriasis rosea
0.000 0.630 0.370
E46 Unspecified protein-energy malnutrition
0.000 0.640 0.360
G36 Other acute disseminated demyelination
0.000 0.640 0.360
E56.9 Vitamin deficiency, unspecified
0.000 0.642 0.358
E56.8 Deficiency of other vitamins
0.000 0.642 0.358
E56.0 Deficiency of vitamin E
0.000 0.642 0.358
E88 Other metabolic disorders
0.000 0.653 0.347
E53.1 Pyridoxine deficiency
0.000 0.657 0.343
E53.0 Riboflavin deficiency
0.000 0.657 0.343
E07.8 Other specified disorders of thyroid
0.001 0.658 0.341
E85.4 Organ-limited amyloidosis
0.000 0.661 0.339
E07.1 Dyshormogenetic goitre
0.001 0.663 0.336
E07.0 Hypersecretion of calcitonin
0.001 0.663 0.336
E84 Cystic fibrosis
0.000 0.663 0.337
E79 Disorders of purine and pyrimidine metabolism
0.000 0.663 0.337
E77 Disorders of glycoprotein metabolism
0.000 0.663 0.337
E76 Disorders of glycosaminoglycan metabolism
0.000 0.663 0.337
E72 Other disorders of amino-acid metabolism
0.000 0.663 0.337
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.663 0.337
E70 Disorders of aromatic amino-acid metabolism
0.000 0.663 0.337
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.663 0.337
E14.4 With neurological complications
0.000 0.664 0.336
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.665 0.335
L44 Other papulosquamous disorders
0.000 0.669 0.330
L41 Parapsoriasis
0.000 0.669 0.330
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.669 0.330
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.670 0.330
E83.8 Other disorders of mineral metabolism
0.000 0.670 0.330
E83.2 Disorders of zinc metabolism
0.000 0.670 0.330
E83.0 Disorders of copper metabolism
0.000 0.670 0.330
E74 Other disorders of carbohydrate metabolism
0.000 0.676 0.324
E44.1 Mild protein-energy malnutrition
0.000 0.678 0.322
E44.0 Moderate protein-energy malnutrition
0.000 0.678 0.322
L43 Lichen planus
0.000 0.680 0.320
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.681 0.318
E61.1 Iron deficiency
0.000 0.681 0.318
G37.5 Concentric sclerosis [Balo]
0.000 0.684 0.316
G37.4 Subacute necrotising myelitis
0.000 0.684 0.316
G37.2 Central pontine myelinolysis
0.000 0.684 0.316
G37.1 Central demyelination of corpus callosum
0.000 0.684 0.316
G37.0 Diffuse sclerosis
0.000 0.684 0.316
E14.1 With ketoacidosis
0.000 0.688 0.312
E14.8 With unspecified complications
0.000 0.689 0.310
E14.7 With multiple complications
0.000 0.689 0.310
E14.2 Withrenal complications
0.000 0.689 0.310
E14.0 With coma
0.000 0.689 0.310
E14.3 With ophthalmic complications
0.000 0.693 0.307
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.695 0.305
E73 Lactose intolerance
0.000 0.697 0.302
E85.9 Amyloidosis, unspecified
0.000 0.709 0.291
E14.6 With other specified complications
0.000 0.709 0.291
E56.1 Deficiency of vitamin K
0.001 0.711 0.288
E85.8 Other amyloidosis
0.000 0.716 0.283
E85.3 Secondary systemic amyloidosis
0.000 0.716 0.283
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.716 0.283
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.716 0.283
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.716 0.283
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.719 0.281
E14.5 With peripheral circulatory complications
0.000 0.727 0.273
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.728 0.272
E88.2 Lipomatosis, not elsewhere classified
0.000 0.733 0.267
L43.8 Other lichen planus
0.000 0.737 0.263
G36.9 Acute disseminated demyelination, unspecified
0.000 0.742 0.258
G36.8 Other specified acute disseminated demyelination
0.000 0.742 0.258
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.742 0.258
E04 Other non-toxic goitre
0.000 0.749 0.251
E88.9 Metabolic disorder, unspecified
0.000 0.751 0.249
G36.0 Neuromyelitis optica [Devic]
0.000 0.755 0.245
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.758 0.241
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.758 0.241
E70.3 Albinism
0.000 0.758 0.241
E70.2 Disorders of tyrosine metabolism
0.000 0.758 0.241
E70.1 Other hyperphenylalaninaemias
0.000 0.758 0.241
E70.0 Classical phenylketonuria
0.000 0.758 0.241
E71.3 Disorders of fatty-acid metabolism
0.000 0.758 0.241
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.758 0.241
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.758 0.241
E71.0 Maple-syrup-urine disease
0.000 0.758 0.241
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.758 0.241
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.758 0.241
E72.5 Disorders of glycine metabolism
0.000 0.758 0.241
E72.4 Disorders of ornithine metabolism
0.000 0.758 0.241
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.758 0.241
E72.2 Disorders of urea cycle metabolism
0.000 0.758 0.241
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.758 0.241
E72.0 Disorders of amino-acid transport
0.000 0.758 0.241
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.758 0.241
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.758 0.241
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.758 0.241
E76.2 Other mucopolysaccharidoses
0.000 0.758 0.241
E76.1 Mucopolysaccharidosis, type II
0.000 0.758 0.241
E76.0 Mucopolysaccharidosis, type I
0.000 0.758 0.241
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.758 0.241
E77.8 Other disorders of glycoprotein metabolism
0.000 0.758 0.241
E77.1 Defects in glycoprotein degradation
0.000 0.758 0.241
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.758 0.241
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.758 0.241
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.758 0.241
E79.1 Lesch-Nyhan syndrome
0.000 0.758 0.241
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.758 0.241
E84.9 Cystic fibrosis, unspecified
0.000 0.758 0.241
E84.8 Cystic fibrosis with other manifestations
0.000 0.758 0.241
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.758 0.241
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.758 0.241
E88.3 Tumour lysis syndrome
0.000 0.760 0.240
L41.9 Parapsoriasis, unspecified
0.000 0.763 0.237
L41.8 Other parapsoriasis
0.000 0.763 0.237
L41.5 Retiform parapsoriasis
0.000 0.763 0.237
L41.4 Large plaque parapsoriasis
0.000 0.763 0.237
L41.3 Small plaque parapsoriasis
0.000 0.763 0.237
L41.2 Lymphomatoid papulosis
0.000 0.763 0.237
L41.1 Pityriasis lichenoides chronica
0.000 0.763 0.237
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.763 0.237
L44.9 Papulosquamous disorder, unspecified
0.000 0.763 0.237
L44.8 Other specified papulosquamous disorders
0.000 0.763 0.237
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.763 0.237
L44.3 Lichen ruber moniliformis
0.000 0.763 0.237
L44.2 Lichen striatus
0.000 0.763 0.237
L44.1 Lichen nitidus
0.000 0.763 0.237
L44.0 Pityriasis rubra pilaris
0.000 0.763 0.237
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.763 0.236
E86 Volume depletion
0.000 0.766 0.234
E88.8 Other specified metabolic disorders
0.000 0.767 0.233
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.768 0.232
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.768 0.232
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.768 0.232
E74.2 Disorders of galactose metabolism
0.000 0.768 0.232
E74.1 Disorders of fructose metabolism
0.000 0.768 0.232
E74.0 Glycogen storage disease
0.000 0.768 0.232
L43.3 Subacute (active) lichen planus
0.000 0.770 0.230
L43.2 Lichenoid drug reaction
0.000 0.770 0.230
L43.1 Bullous lichen planus
0.000 0.770 0.230
L43.0 Hypertrophic lichen planus
0.000 0.770 0.230
E75.6 Lipid storage disorder, unspecified
0.000 0.771 0.228
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.771 0.228
E75.3 Sphingolipidosis, unspecified
0.000 0.771 0.228
E75.2 Other sphingolipidosis
0.000 0.771 0.228
E75.1 Other gangliosidosis
0.000 0.771 0.228
E75.0 GM2 gangliosidosis
0.000 0.771 0.228
E89.2 Postprocedural hypoparathyroidism
0.000 0.773 0.227
E83.4 Disorders of magnesium metabolism
0.000 0.778 0.222
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.781 0.219
E73.8 Other lactose intolerance
0.000 0.783 0.217
E73.1 Secondary lactase deficiency
0.000 0.783 0.217
E73.0 Congenital lactase deficiency
0.000 0.783 0.217
E75.5 Other lipid storage disorders
0.000 0.789 0.210
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.799 0.201
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.799 0.201
E89.5 Postprocedural testicular hypofunction
0.000 0.799 0.201
E89.1 Postprocedural hypoinsulinaemia
0.000 0.799 0.201
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.806 0.194
E04.0 Non-toxic diffuse goitre
0.000 0.813 0.187
E89.4 Postprocedural ovarian failure
0.000 0.814 0.185
E20-E35 Disorders of other endocrine glands
0.000 0.814 0.185
E89.0 Postprocedural hypothyroidism
0.000 0.815 0.185
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.816 0.184
E73.9 Lactose intolerance, unspecified
0.000 0.817 0.183
E04.8 Other specified non-toxic goitre
0.000 0.820 0.180
E53.8 Deficiency of other specified B group vitamins
0.000 0.820 0.180
E83.3 Disorders of phosphorus metabolism
0.000 0.824 0.176
L43.9 Lichen planus, unspecified
0.000 0.837 0.163
E04.9 Non-toxic goitre, unspecified
0.000 0.843 0.157
E89.3 Postprocedural hypopituitarism
0.000 0.847 0.153
E22 Hyperfunction of pituitary gland
0.000 0.860 0.139
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.865 0.135
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.867 0.133
E32 Diseases of thymus
0.000 0.867 0.133
E31 Polyglandular dysfunction
0.000 0.867 0.133
E30 Disorders of puberty, not elsewhere classified
0.000 0.867 0.133
E25 Adrenogenital disorders
0.000 0.867 0.133
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.868 0.132
E80.5 Crigler-Najjar syndrome
0.000 0.868 0.132
E80.3 Defects of catalase and peroxydase
0.000 0.868 0.132
E80.1 Porphyria cutanea tarda
0.000 0.868 0.132
E80.0 Hereditary erythropoietic porphyria
0.000 0.868 0.132
E20 Hypoparathyroidism
0.000 0.869 0.131
E26 Hyperaldosteronism
0.000 0.877 0.122
E34 Other endocrine disorders
0.000 0.879 0.121
E27 Other disorders of adrenal gland
0.000 0.880 0.120
E22.1 Hyperprolactinaemia
0.000 0.881 0.119
E80.6 Other disorders of bilirubin metabolism
0.000 0.881 0.118
E80.2 Other porphyria
0.000 0.884 0.116
E29 Testicular dysfunction
0.000 0.885 0.115
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.886 0.114
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.886 0.114
E24 Cushing's syndrome
0.000 0.887 0.113
E21.0 Primary hyperparathyroidism
0.000 0.890 0.110
E22.0 Acromegaly and pituitary gigantism
0.000 0.893 0.107
E27.1 Primary adrenocortical insufficiency
0.000 0.894 0.106
E23 Hypofunction and other disorders of pituitary gland
0.000 0.894 0.105
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.900 0.100
E22.8 Other hyperfunction of pituitary gland
0.000 0.900 0.100
E14.9 Without complications
0.000 0.900 0.100
E87.5 Hyperkalaemia
0.000 0.901 0.099
M45-M49 Spondylopathies
0.099 0.901 0.000
E34.0 Carcinoid syndrome
0.000 0.903 0.097
E21.4 Other specified disorders of parathyroid gland
0.000 0.903 0.097
E21.2 Other hyperparathyroidism
0.000 0.903 0.097
E25.9 Adrenogenital disorder, unspecified
0.000 0.904 0.095
E25.8 Other adrenogenital disorders
0.000 0.904 0.095
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.904 0.095
E30.9 Disorder of puberty, unspecified
0.000 0.904 0.095
E30.8 Other disorders of puberty
0.000 0.904 0.095
E30.1 Precocious puberty
0.000 0.904 0.095
E30.0 Delayed puberty
0.000 0.904 0.095
E31.9 Polyglandular dysfunction, unspecified
0.000 0.904 0.095
E31.8 Other polyglandular dysfunction
0.000 0.904 0.095
E31.1 Polyglandular hyperfunction
0.000 0.904 0.095
E31.0 Autoimmune polyglandular failure
0.000 0.904 0.095
E32.9 Disease of thymus, unspecified
0.000 0.904 0.095
E32.8 Other diseases of thymus
0.000 0.904 0.095
E32.1 Abscess of thymus
0.000 0.904 0.095
E32.0 Persistent hyperplasia of thymus
0.000 0.904 0.095
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.904 0.095
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.904 0.095
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.904 0.095
E20.8 Other hypoparathyroidism
0.000 0.906 0.094
E20.1 Pseudohypoparathyroidism
0.000 0.906 0.094
E20.0 Idiopathic hypoparathyroidism
0.000 0.906 0.094
E20.9 Hypoparathyroidism, unspecified
0.000 0.908 0.092
E23.6 Other disorders of pituitary gland
0.000 0.912 0.088
E26.9 Hyperaldosteronism, unspecified
0.000 0.912 0.088
E26.8 Other hyperaldosteronism
0.000 0.912 0.088
E26.1 Secondary hyperaldosteronism
0.000 0.912 0.088
E87.2 Acidosis
0.000 0.912 0.088
E27.8 Other specified disorders of adrenal gland
0.000 0.913 0.087
E34.5 Androgen resistance syndrome
0.000 0.913 0.087
E34.4 Constitutional tall stature
0.000 0.913 0.087
E34.3 Short stature, not elsewhere classified
0.000 0.913 0.087
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.913 0.087
E34.1 Other hypersecretion of intestinal hormones
0.000 0.913 0.087
E87.7 Fluid overload
0.000 0.913 0.087
E27.5 Adrenomedullary hyperfunction
0.000 0.914 0.086
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.914 0.086
E27.0 Other adrenocortical overactivity
0.000 0.914 0.086
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.914 0.085
E07.9 Disorder of thyroid, unspecified
0.002 0.916 0.082
E04.2 Non-toxic multinodular goitre
0.000 0.916 0.083
M06.9 Rheumatoid arthritis, unspecified
0.083 0.917 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.083 0.917 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.917 0.083
E29.8 Other testicular dysfunction
0.000 0.917 0.083
E29.0 Testicular hyperfunction
0.000 0.917 0.083
E23.7 Disorder of pituitary gland, unspecified
0.000 0.918 0.082
E87.4 Mixed disorder of acid-base balance
0.000 0.918 0.082
E24.8 Other Cushing's syndrome
0.000 0.919 0.081
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.919 0.081
E24.3 Ectopic ACTH syndrome
0.000 0.919 0.081
E24.1 Nelson's syndrome
0.000 0.919 0.081
E24.0 Pituitary-dependent Cushing's disease
0.000 0.919 0.081
E34.9 Endocrine disorder, unspecified
0.000 0.919 0.081
E26.0 Primary hyperaldosteronism
0.000 0.922 0.077
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.077 0.923 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.924 0.076
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.924 0.076
E23.1 Drug-induced hypopituitarism
0.000 0.924 0.076
M06 Other rheumatoid arthritis
0.075 0.925 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.926 0.074
E27.9 Disorder of adrenal gland, unspecified
0.000 0.926 0.074
E87.3 Alkalosis
0.000 0.927 0.073
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.928 0.072
M06.0 Seronegative rheumatoid arthritis
0.072 0.928 0.000
M46 Other inflammatory spondylopathies
0.072 0.928 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.929 0.071
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.069 0.931 0.000
E87.6 Hypokalaemia
0.000 0.932 0.068
E78.2 Mixed hyperlipidaemia
0.000 0.934 0.066
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.065 0.935 0.000
E29.1 Testicular hypofunction
0.000 0.935 0.065
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.065 0.935 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.065 0.935 0.000
M06.3 Rheumatoid nodule
0.065 0.935 0.000
M49 Spondylopathies in diseases classified elsewhere
0.064 0.936 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.064 0.936 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.064 0.936 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.936 0.063
E34.8 Other specified endocrine disorders
0.001 0.936 0.063
E27.2 Addisonian crisis
0.000 0.936 0.063
E04.1 Non-toxic single thyroid nodule
0.000 0.937 0.063
E80.4 Gilbert's syndrome
0.000 0.939 0.060
E28 Ovarian dysfunction
0.003 0.939 0.057
M06.98 Rheumatoid arthritis, unspecified (Other)
0.060 0.940 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.940 0.059
M06.34 Rheumatoid nodule (Hand)
0.059 0.940 0.000
E78.6 Lipoprotein deficiency
0.000 0.941 0.059
M46.2 Osteomyelitis of vertebra
0.058 0.942 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.056 0.944 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.055 0.945 0.000
E78.4 Other hyperlipidaemia
0.000 0.945 0.055
E78.8 Other disorders of lipoprotein metabolism
0.000 0.945 0.055
E78.3 Hyperchylomicronaemia
0.000 0.945 0.055
M06.8 Other specified rheumatoid arthritis
0.054 0.946 0.000
M06.2 Rheumatoid bursitis
0.054 0.946 0.000
M06.1 Adult-onset Still's disease
0.054 0.946 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.947 0.052
M48 Other spondylopathies
0.052 0.947 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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