TreeWAS – Variant ID: rs2233974

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
M35.0 Sicca syndrome [Sjogren]	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.999	0.001	0.000
D80-D89 Certain disorders involving the immune mechanism	0.999	0.001	0.000
D64.9 Anaemia, unspecified	0.999	0.001	0.000
E16 Other disorders of pancreatic internal secretion	0.999	0.001	0.000
H36 Retinal disorders in diseases classified elsewhere	0.999	0.001	0.000
Chapter I Certain infectious and parasitic diseases	0.999	0.001	0.000
E16.2 Hypoglycaemia, unspecified	0.999	0.001	0.000
K70-K77 Diseases of liver	0.999	0.001	0.000
E14 Unspecified diabetes mellitus	0.999	0.001	0.000
H30-H36 Disorders of choroid and retina	0.999	0.001	0.000
K75 Other inflammatory liver diseases	0.998	0.002	0.000
Chapter VI Diseases of the nervous system	0.998	0.002	0.000
Chapter VII Diseases of the eye and adnexa	0.998	0.002	0.000
E10.1 With ketoacidosis	0.998	0.002	0.000
K75.4 Autoimmune hepatitis	0.997	0.003	0.000
G35 Multiple sclerosis	0.997	0.003	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.997	0.003	0.000
D86 Sarcoidosis	0.996	0.004	0.000
B35-B49 Mycoses	0.995	0.005	0.000
D61 Other aplastic anaemias	0.994	0.006	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.994	0.006	0.000
M35 Other systemic involvement of connective tissue	0.993	0.007	0.000
B37 Candidiasis	0.993	0.007	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.993	0.007	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.992	0.008	0.000
E20-E35 Disorders of other endocrine glands	0.991	0.009	0.000
E14.3 With ophthalmic complications	0.991	0.009	0.000
D61.9 Aplastic anaemia, unspecified	0.989	0.011	0.000
N40 Hyperplasia of prostate	0.000	0.012	0.988
E10.2 With renal complications	0.988	0.012	0.000
A30-A49 Other bacterial diseases	0.987	0.013	0.000
N40-N51 Diseases of male genital organs	0.000	0.014	0.986
G50-G59 Nerve, nerve root and plexus disorders	0.986	0.014	0.000
E89.0 Postprocedural hypothyroidism	0.985	0.015	0.000
D86.9 Sarcoidosis, unspecified	0.985	0.015	0.000
E70-E90 Metabolic disorders	0.984	0.016	0.000
A41 Other septicaemia	0.984	0.016	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.983	0.017	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.983	0.017	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.018	0.982
C81 Hodgkin's disease	0.978	0.022	0.000
K72 Hepatic failure, not elsewhere classified	0.978	0.022	0.000
C85.1 B-cell lymphoma, unspecified	0.977	0.023	0.000
E27 Other disorders of adrenal gland	0.975	0.025	0.000
G56 Mononeuropathies of upper limb	0.975	0.025	0.000
E10.4 With neurological complications	0.974	0.026	0.000
E27.1 Primary adrenocortical insufficiency	0.973	0.027	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.972	0.028	0.000
G56.0 Carpal tunnel syndrome	0.972	0.028	0.000
B37.8 Candidiasis of other sites	0.969	0.031	0.000
D50-D53 Nutritional anaemias	0.969	0.031	0.000
E50-E64 Other nutritional deficiencies	0.967	0.033	0.000
Chapter IX Diseases of the circulatory system	0.965	0.035	0.000
N00-N08 Glomerular diseases	0.965	0.035	0.000
Chapter XI Diseases of the digestive system	0.946	0.036	0.018
I70-I79 Diseases of arteries, arterioles and capillaries	0.964	0.036	0.000
Chapter XIV Diseases of the genitourinary system	0.957	0.043	0.000
N04 Nephrotic syndrome	0.957	0.043	0.000
K73 Chronic hepatitis, not elsewhere classified	0.956	0.044	0.000
H34 Retinal vascular occlusions	0.956	0.044	0.000
G30-G32 Other degenerative diseases of the nervous system	0.954	0.046	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.047	0.953
C83.3 Large cell (diffuse)	0.952	0.048	0.000
N05 Unspecified nephritic syndrome	0.952	0.048	0.000
B37.9 Candidiasis, unspecified	0.950	0.050	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.050	0.950
I74 Arterial embolism and thrombosis	0.949	0.051	0.000
K40 Inguinal hernia	0.000	0.052	0.948
M35.3 Polymyalgia rheumatica	0.948	0.052	0.000
M20-M25 Other joint disorders	0.945	0.055	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.943	0.057	0.000
N04.9 Unspecified	0.940	0.060	0.000
N42 Other disorders of prostate	0.000	0.063	0.937
B37.0 Candidal stomatitis	0.937	0.063	0.000
C81.9 Hodgkin's disease, unspecified	0.936	0.064	0.000
I60-I69 Cerebrovascular diseases	0.935	0.065	0.000
D86.0 Sarcoidosis of lung	0.934	0.066	0.000
I63 Cerebral infarction	0.934	0.066	0.000
K72.0 Acute and subacute hepatic failure	0.932	0.068	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.930	0.070	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.925	0.075	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.923	0.077	0.000
N17-N19 Renal failure	0.918	0.082	0.000
D69 Purpura and other haemorrhagic conditions	0.918	0.082	0.000
K70 Alcoholic liver disease	0.917	0.083	0.000
K75.8 Other specified inflammatory liver diseases	0.916	0.084	0.000
Chapter XX External causes of morbidity and mortality	0.916	0.084	0.000
H34.8 Other retinal vascular occlusions	0.915	0.085	0.000
N05.2 Diffuse membranous glomerulonephritis	0.915	0.085	0.000
A41.9 Septicaemia, unspecified	0.913	0.087	0.000
G51 Facial nerve disorders	0.913	0.087	0.000
I73 Other peripheral vascular diseases	0.910	0.090	0.000
N18 Chronic renal failure	0.909	0.091	0.000
W00-W19 Falls	0.908	0.092	0.000
D80 Immunodeficiency with predominantly antibody defects	0.906	0.094	0.000
D50 Iron deficiency anaemia	0.905	0.095	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.903	0.096	0.001
W19 Unspecified fall	0.903	0.097	0.000
K74 Fibrosis and cirrhosis of liver	0.900	0.100	0.000
E11 Non-insulin-dependent diabetes mellitus	0.900	0.100	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.899	0.101	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.896	0.104	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.105	0.895
I63.8 Other cerebral infarction	0.894	0.106	0.000
E06 Thyroiditis	0.893	0.107	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.892	0.107	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.893	0.107	0.000
E11.3 With ophthalmic complications	0.888	0.112	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.888	0.112	0.000
K72.9 Hepatic failure, unspecified	0.886	0.114	0.000
W19.9 Unspecified place	0.885	0.115	0.000
H06.2 Dysthyroid exophthalmos	0.885	0.115	0.000
D69.6 Thrombocytopenia, unspecified	0.882	0.118	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.882	0.118	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.881	0.119	0.000
E24 Cushing's syndrome	0.880	0.120	0.000
I73.9 Peripheral vascular disease, unspecified	0.875	0.125	0.000
N18.9 Chronic renal failure, unspecified	0.874	0.126	0.000
B02 Zoster [herpes zoster]	0.874	0.126	0.000
C81.1 Nodular sclerosis	0.874	0.126	0.000
K70.4 Alcoholic hepatic failure	0.872	0.128	0.000
E53 Deficiency of other B group vitamins	0.871	0.129	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.867	0.133	0.000
E03.8 Other specified hypothyroidism	0.867	0.133	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.866	0.134	0.000
G51.0 Bell's palsy	0.860	0.140	0.000
C88 Malignant immunoproliferative diseases	0.860	0.140	0.000
D50.8 Other iron deficiency anaemias	0.859	0.141	0.000
N48 Other disorders of penis	0.000	0.143	0.857
H30 Chorioretinal inflammation	0.857	0.143	0.000
I77 Other disorders of arteries and arterioles	0.856	0.144	0.000
E73 Lactose intolerance	0.854	0.146	0.000
D51 Vitamin B12 deficiency anaemia	0.854	0.146	0.000
M35.7 Hypermobility syndrome	0.850	0.150	0.000
K90-K93 Other diseases of the digestive system	0.841	0.152	0.006
H00.1 Chalazion	0.000	0.152	0.847
G31.8 Other specified degenerative diseases of nervous system	0.847	0.153	0.000
K73.9 Chronic hepatitis, unspecified	0.846	0.154	0.000
I63.9 Cerebral infarction, unspecified	0.844	0.156	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.844	0.156	0.000
E55 Vitamin D deficiency	0.844	0.156	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.843	0.157	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.843	0.157	0.000
E14.1 With ketoacidosis	0.843	0.157	0.000
E14.9 Without complications	0.840	0.160	0.000
K90 Intestinal malabsorption	0.835	0.163	0.001
E07 Other disorders of thyroid	0.836	0.164	0.000
E10.5 With peripheral circulatory complications	0.833	0.167	0.000
M60-M63 Disorders of muscles	0.831	0.169	0.000
K74.6 Other and unspecified cirrhosis of liver	0.829	0.171	0.000
E11.1 With ketoacidosis	0.829	0.171	0.000
N25-N29 Other disorders of kidney and ureter	0.828	0.172	0.000
M32 Systemic lupus erythematosus	0.826	0.173	0.000
I10-I15 Hypertensive diseases	0.826	0.174	0.000
E10.7 With multiple complications	0.825	0.174	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.825	0.175	0.000
E14.2 Withrenal complications	0.825	0.175	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.823	0.177	0.000
N18.3 Chronic kidney disease, stage 3	0.822	0.178	0.000
N04.1 Focal and segmental glomerular lesions	0.820	0.180	0.000
E23 Hypofunction and other disorders of pituitary gland	0.819	0.181	0.000
C91 Lymphoid leukaemia	0.819	0.181	0.000
N42.8 Other specified disorders of prostate	0.000	0.183	0.817
B02.9 Zoster without complication	0.817	0.183	0.000
M33 Dermatopolymyositis	0.815	0.185	0.000
E06.3 Autoimmune thyroiditis	0.815	0.185	0.000
E14.8 With unspecified complications	0.813	0.187	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.813	0.187	0.000
H43-H45 Disorders of vitreous body and globe	0.812	0.188	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.811	0.189	0.000
I77.1 Stricture of artery	0.810	0.190	0.000
D83 Common variable immunodeficiency	0.809	0.191	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.191	0.809
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.805	0.195	0.000
K90.9 Intestinal malabsorption, unspecified	0.805	0.195	0.000
D86.1 Sarcoidosis of lymph nodes	0.804	0.196	0.000
I71 Aortic aneurysm and dissection	0.803	0.197	0.000
E53.8 Deficiency of other specified B group vitamins	0.801	0.199	0.000
C81.2 Mixed cellularity	0.800	0.200	0.000
A48 Other bacterial diseases, not elsewhere classified	0.799	0.201	0.000
B15-B19 Viral hepatitis	0.799	0.201	0.000
I12 Hypertensive renal disease	0.798	0.202	0.000
E10.0 With coma	0.798	0.202	0.000
D64.8 Other specified anaemias	0.798	0.202	0.000
I74.5 Embolism and thrombosis of iliac artery	0.797	0.203	0.000
E88 Other metabolic disorders	0.797	0.203	0.000
E51 Thiamine deficiency	0.797	0.203	0.000
B37.7 Candidal septicaemia	0.796	0.204	0.000
D69.4 Other primary thrombocytopenia	0.794	0.206	0.000
E10.8 With unspecified complications	0.793	0.207	0.000
G56.1 Other lesions of median nerve	0.792	0.208	0.000
W19.1 Residential institution	0.792	0.208	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.791	0.209	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.791	0.209	0.000
G51.9 Disorder of facial nerve, unspecified	0.787	0.213	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.787	0.213	0.000
K50-K52 Noninfective enteritis and colitis	0.707	0.213	0.079
M34 Systemic sclerosis	0.786	0.214	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.786	0.214	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.785	0.215	0.000
Q50-Q56 Congenital malformations of genital organs	0.785	0.215	0.000
W05 Fall involving wheelchair	0.785	0.215	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.784	0.215	0.000
G52 Disorders of other cranial nerves	0.784	0.216	0.000
I12.9 Hypertensive renal disease without renal failure	0.782	0.218	0.000
N05.1 Focal and segmental glomerular lesions	0.782	0.218	0.000
W13 Fall from, out of or through building or structure	0.779	0.221	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.779	0.221	0.000
M15-M19 Arthrosis	0.779	0.221	0.000
X20-X29 Contact with venomous animals and plants	0.777	0.223	0.000
I62 Other nontraumatic intracranial haemorrhage	0.777	0.223	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.777	0.223	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.776	0.224	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.774	0.226	0.000
V40-V49 Car occupant injured in transport accident	0.773	0.227	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.773	0.227	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.771	0.228	0.000
C83.0 Small cell (diffuse)	0.770	0.230	0.000
W19.2 School, other institution and public administrative area	0.770	0.230	0.000
N04.2 Diffuse membranous glomerulonephritis	0.768	0.232	0.000
E31 Polyglandular dysfunction	0.766	0.234	0.000
G30 Alzheimer's disease	0.766	0.234	0.000
I77.6 Arteritis, unspecified	0.765	0.235	0.000
H34.2 Other retinal artery occlusions	0.765	0.235	0.000
I74.8 Embolism and thrombosis of other arteries	0.764	0.236	0.000
M22 Disorders of patella	0.764	0.236	0.000
E24.2 Drug-induced Cushing's syndrome	0.764	0.236	0.000
X10-X19 Contact with heat and hot substances	0.763	0.237	0.000
G31.0 Circumscribed brain atrophy	0.762	0.238	0.000
E73.9 Lactose intolerance, unspecified	0.761	0.239	0.000
E55.9 Vitamin D deficiency, unspecified	0.755	0.245	0.000
H30.9 Chorioretinal inflammation, unspecified	0.755	0.245	0.000
E74 Other disorders of carbohydrate metabolism	0.755	0.245	0.000
B37.2 Candidiasis of skin and nail	0.754	0.246	0.000
D53 Other nutritional anaemias	0.753	0.247	0.000
B44 Aspergillosis	0.753	0.247	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.752	0.248	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.752	0.248	0.000
B00 Herpesviral [herpes simplex] infections	0.750	0.250	0.000
N48.1 Balanoposthitis	0.000	0.250	0.750
D61.0 Constitutional aplastic anaemia	0.750	0.250	0.000
W06 Fall involving bed	0.749	0.251	0.000
V01-V09 Pedestrian injured in transport accident	0.749	0.251	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.747	0.253	0.000
B25-B34 Other viral diseases	0.746	0.254	0.000
D50.1 Sideropenic dysphagia	0.746	0.254	0.000
D55-D59 Haemolytic anaemias	0.746	0.254	0.000
G70-G73 Diseases of myoneural junction and muscle	0.746	0.254	0.000
E24.0 Pituitary-dependent Cushing's disease	0.745	0.255	0.000
K52 Other non-infective gastro-enteritis and colitis	0.695	0.256	0.049
N00 Acute nephritic syndrome	0.744	0.256	0.000
M35.1 Other overlap syndromes	0.743	0.257	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.258	0.742
N18.0 End-stage renal disease	0.741	0.258	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.741	0.258	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.741	0.259	0.000
N05.9 Unspecified	0.740	0.260	0.000
D86.3 Sarcoidosis of skin	0.739	0.261	0.000
E21.3 Hyperparathyroidism, unspecified	0.739	0.261	0.000
C83.7 Burkitt's tumour	0.739	0.261	0.000
E14.6 With other specified complications	0.739	0.261	0.000
E58 Dietary calcium deficiency	0.738	0.261	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.738	0.262	0.000
V20-V29 Motorcycle rider injured in transport accident	0.738	0.262	0.000
A63.0 Anogenital (venereal) warts	0.738	0.262	0.000
B35 Dermatophytosis	0.737	0.263	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.735	0.264	0.001
D69.2 Other nonthrombocytopenic purpura	0.735	0.265	0.000
A65-A69 Other spirochaetal diseases	0.735	0.265	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.735	0.265	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.735	0.265	0.000
D61.1 Drug-induced aplastic anaemia	0.734	0.266	0.000
E10.6 With other specified complications	0.733	0.266	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.267	0.733
I65.2 Occlusion and stenosis of carotid artery	0.731	0.269	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.731	0.269	0.000
N48.4 Impotence of organic origin	0.000	0.270	0.730
M15 Polyarthrosis	0.729	0.271	0.000
W14 Fall from tree	0.726	0.274	0.000
E23.7 Disorder of pituitary gland, unspecified	0.726	0.274	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.726	0.274	0.000
B65-B83 Helminthiases	0.724	0.276	0.000
M17 Gonarthrosis [arthrosis of knee]	0.722	0.278	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.722	0.278	0.000
C93 Monocytic leukaemia	0.722	0.278	0.000
E20 Hypoparathyroidism	0.721	0.279	0.000
K74.3 Primary biliary cirrhosis	0.721	0.279	0.000
M00-M03 Infectious arthropathies	0.720	0.280	0.000
W19.3 Sports and athletics area	0.719	0.281	0.000
N18.8 Other chronic renal failure	0.718	0.282	0.000
M60 Myositis	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
D82 Immunodeficiency associated with other major defects	0.716	0.283	0.000
D81 Combined immunodeficiencies	0.716	0.283	0.000
Q51 Congenital malformations of uterus and cervix	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.716	0.284	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.716	0.284	0.000
E16.4 Abnormal secretion of gastrin	0.716	0.284	0.000
E16.3 Increased secretion of glucagon	0.716	0.284	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.716	0.284	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.716	0.284	0.000
A75-A79 Rickettsioses	0.716	0.284	0.000
A70-A74 Other diseases caused by chlamydiae	0.716	0.284	0.000
A20-A28 Certain zoonotic bacterial diseases	0.716	0.284	0.000
C83.1 Small cleaved cell (diffuse)	0.716	0.284	0.000
K77 Liver disorders in diseases classified elsewhere	0.716	0.284	0.000
K71 Toxic liver disease	0.716	0.284	0.000
E14.7 With multiple complications	0.716	0.284	0.000
E14.0 With coma	0.716	0.284	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.716	0.284	0.000
K75.2 Nonspecific reactive hepatitis	0.716	0.284	0.000
K75.1 Phlebitis of portal vein	0.716	0.284	0.000
N48.2 Other inflammatory disorders of penis	0.000	0.284	0.716
D69.9 Haemorrhagic condition, unspecified	0.715	0.285	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.715	0.285	0.000
G36 Other acute disseminated demyelination	0.715	0.285	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.714	0.285	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.715	0.285	0.000
K70.0 Alcoholic fatty liver	0.714	0.286	0.000
B48 Other mycoses, not elsewhere classified	0.713	0.287	0.000
B47 Mycetoma	0.713	0.287	0.000
B46 Zygomycosis	0.713	0.287	0.000
B45 Cryptococcosis	0.713	0.287	0.000
B43 Chromomycosis and phaeomycotic abscess	0.713	0.287	0.000
B42 Sporotrichosis	0.713	0.287	0.000
B41 Paracoccidioidomycosis	0.713	0.287	0.000
B40 Blastomycosis	0.713	0.287	0.000
B39 Histoplasmosis	0.713	0.287	0.000
B38 Coccidioidomycosis	0.713	0.287	0.000
M17.1 Other primary gonarthrosis	0.713	0.287	0.000
H43 Disorders of vitreous body	0.713	0.287	0.000
D61.8 Other specified aplastic anaemias	0.713	0.287	0.000
D61.3 Idiopathic aplastic anaemia	0.713	0.287	0.000
D61.2 Aplastic anaemia due to other external agents	0.713	0.287	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.713	0.287	0.000
C85.0 Lymphosarcoma	0.713	0.287	0.000
X58 Exposure to other specified factors	0.712	0.288	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.712	0.288	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.712	0.288	0.000
M35.5 Multifocal fibrosclerosis	0.712	0.288	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.712	0.288	0.000
B37.6 Candidal endocarditis	0.712	0.288	0.000
B37.5 Candidal meningitis	0.712	0.288	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.712	0.288	0.000
C94 Other leukaemias of specified cell type	0.712	0.288	0.000
C86 Other specified types of T/NK-cell lymphoma	0.712	0.288	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.710	0.290	0.000
E32 Diseases of thymus	0.710	0.290	0.000
E30 Disorders of puberty, not elsewhere classified	0.710	0.290	0.000
E25 Adrenogenital disorders	0.710	0.290	0.000
A15-A19 Tuberculosis	0.710	0.290	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.710	0.290	0.000
K75.0 Abscess of liver	0.710	0.290	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.710	0.290	0.000
B02.3 Zoster ocular disease	0.709	0.291	0.000
G54 Nerve root and plexus disorders	0.709	0.291	0.000
G58 Other mononeuropathies	0.709	0.291	0.000
N42.2 Atrophy of prostate	0.000	0.291	0.709
Chapter II Neoplasms	0.708	0.292	0.000
A44 Bartonellosis	0.707	0.292	0.000
A43 Nocardiosis	0.707	0.292	0.000
A42 Actinomycosis	0.707	0.292	0.000
A37 Whooping cough	0.707	0.292	0.000
A36 Diphtheria	0.707	0.292	0.000
A32 Listeriosis	0.707	0.292	0.000
A30 Leprosy [Hansen's disease]	0.707	0.292	0.000
A38 Scarlet fever	0.707	0.292	0.000
A35 Other tetanus	0.707	0.292	0.000
A34 Obstetrical tetanus	0.707	0.292	0.000
A33 Tetanus neonatorum	0.707	0.292	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.000	0.293	0.707
N44 Torsion of testis	0.000	0.293	0.707
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.706	0.294	0.000
E84 Cystic fibrosis	0.706	0.294	0.000
E79 Disorders of purine and pyrimidine metabolism	0.706	0.294	0.000
E77 Disorders of glycoprotein metabolism	0.706	0.294	0.000
E76 Disorders of glycosaminoglycan metabolism	0.706	0.294	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.706	0.294	0.000
E72 Other disorders of amino-acid metabolism	0.706	0.294	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.706	0.294	0.000
E70 Disorders of aromatic amino-acid metabolism	0.706	0.294	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.706	0.294	0.000
A41.4 Septicaemia due to anaerobes	0.706	0.294	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.706	0.294	0.000
G56.4 Causalgia	0.706	0.294	0.000
M65-M68 Disorders of synovium and tendon	0.706	0.294	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.705	0.295	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.705	0.295	0.000
E89.5 Postprocedural testicular hypofunction	0.705	0.295	0.000
E89.4 Postprocedural ovarian failure	0.705	0.295	0.000
E89.1 Postprocedural hypoinsulinaemia	0.705	0.295	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.703	0.297	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.703	0.297	0.000
M86-M90 Other osteopathies	0.702	0.298	0.000
C81.0 Lymphocytic predominance	0.702	0.298	0.000
C81.7 Other Hodgkin's disease	0.701	0.298	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.701	0.298	0.000
C81.3 Lymphocytic depletion	0.701	0.298	0.000
K72.1 Chronic hepatic failure	0.701	0.299	0.000
D89.1 Cryoglobulinaemia	0.701	0.299	0.000
E14.5 With peripheral circulatory complications	0.700	0.299	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.700	0.299	0.001
E27.5 Adrenomedullary hyperfunction	0.699	0.301	0.000
E27.0 Other adrenocortical overactivity	0.699	0.301	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.699	0.301	0.000
E14.4 With neurological complications	0.699	0.301	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.698	0.301	0.000
C83.6 Undifferentiated (diffuse)	0.697	0.303	0.000
C83.5 Lymphoblastic (diffuse)	0.697	0.303	0.000
C83.4 Immunoblastic (diffuse)	0.697	0.303	0.000
C83.2 Mixed small and large cell (diffuse)	0.697	0.303	0.000
K70.3 Alcoholic cirrhosis of liver	0.697	0.303	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.695	0.305	0.000
N42.0 Calculus of prostate	0.000	0.306	0.694
C92 Myeloid leukaemia	0.694	0.306	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.694	0.306	0.000
E63 Other nutritional deficiencies	0.694	0.306	0.000
E56 Other vitamin deficiencies	0.694	0.306	0.000
E50 Vitamin A deficiency	0.694	0.306	0.000
E60 Dietary zinc deficiency	0.694	0.306	0.000
E59 Dietary selenium deficiency	0.694	0.306	0.000
E54 Ascorbic acid deficiency	0.694	0.306	0.000
E52 Niacin deficiency [pellagra]	0.694	0.306	0.000
H34.9 Retinal vascular occlusion, unspecified	0.694	0.306	0.000
Q39 Congenital malformations of oesophagus	0.693	0.307	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.692	0.308	0.000
N06 Isolated proteinuria with specified morphological lesion	0.692	0.308	0.000
N01 Rapidly progressive nephritic syndrome	0.692	0.308	0.000
N45 Orchitis and epididymitis	0.000	0.308	0.692
G59 Mononeuropathy in diseases classified elsewhere	0.691	0.308	0.000
N18.1 Chronic kidney disease, stage 1	0.690	0.310	0.000
M33.2 Polymyositis	0.690	0.310	0.000
H05 Disorders of orbit	0.689	0.311	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.689	0.311	0.000
C15-C26 Malignant neoplasms of digestive organs	0.688	0.312	0.000
N03 Chronic nephritic syndrome	0.687	0.313	0.000
W13.9 Unspecified place	0.687	0.313	0.000
D62 Acute posthaemorrhagic anaemia	0.686	0.314	0.000
N04.8 Other	0.686	0.314	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.686	0.314	0.000
N04.6 Dense deposit disease	0.686	0.314	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.686	0.314	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.686	0.314	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.686	0.314	0.000
N04.0 Minor glomerular abnormality	0.686	0.314	0.000
I11 Hypertensive heart disease	0.686	0.314	0.000
E61 Deficiency of other nutrient elements	0.686	0.314	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.685	0.314	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.685	0.314	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.685	0.314	0.000
H34.0 Transient retinal artery occlusion	0.685	0.315	0.000
R30-R39 Symptoms and signs involving the urinary system	0.000	0.315	0.685
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.684	0.315	0.000
E07.9 Disorder of thyroid, unspecified	0.685	0.315	0.000
A31 Infection due to other mycobacteria	0.684	0.316	0.000
D69.0 Allergic purpura	0.683	0.317	0.000
N18.5 Chronic kidney disease, stage 5	0.683	0.317	0.000
E11.6 With other specified complications	0.683	0.317	0.000
G50 Disorders of trigeminal nerve	0.683	0.317	0.000
A40 Streptococcal septicaemia	0.682	0.317	0.000
N05.6 Dense deposit disease	0.682	0.318	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.682	0.318	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.682	0.318	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations