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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2235233
log Bayes Factor = 10.6259
Chromosome 6   position 27,279,852  (GRCh37) Explore rs2235233 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.002 0.998
K90 Intestinal malabsorption
0.000 0.469 0.531
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.494 0.506
K90.3 Pancreatic steatorrhoea
0.000 0.619 0.381
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.619 0.381
K90.1 Tropical sprue
0.000 0.619 0.381
K90.8 Other intestinal malabsorption
0.001 0.726 0.273
K90.9 Intestinal malabsorption, unspecified
0.000 0.818 0.182
C25.9 Pancreas, unspecified
0.000 0.850 0.150
C25 Malignant neoplasm of pancreas
0.000 0.871 0.129
C25.0 Head of pancreas
0.000 0.876 0.124
C25.2 Tail of pancreas
0.000 0.887 0.113
C25.3 Pancreatic duct
0.000 0.896 0.104
C25.8 Overlapping lesion of pancreas
0.000 0.907 0.093
C25.4 Endocrine pancreas
0.000 0.907 0.093
C25.7 Other parts of pancreas
0.000 0.912 0.088
E83 Disorders of mineral metabolism
0.000 0.919 0.081
C25.1 Body of pancreas
0.000 0.936 0.063
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.941 0.058
E83.8 Other disorders of mineral metabolism
0.000 0.941 0.058
E83.2 Disorders of zinc metabolism
0.000 0.941 0.058
E83.0 Disorders of copper metabolism
0.000 0.941 0.058
E14 Unspecified diabetes mellitus
0.000 0.952 0.048
E10-E14 Diabetes mellitus
0.000 0.952 0.048
K05.3 Chronic periodontitis
0.000 0.953 0.047
E14.9 Without complications
0.000 0.955 0.045
E14.3 With ophthalmic complications
0.000 0.956 0.044
E11.5 With peripheral circulatory complications
0.000 0.956 0.044
E11 Non-insulin-dependent diabetes mellitus
0.000 0.957 0.043
E10 Insulin-dependent diabetes mellitus
0.000 0.958 0.042
E11.0 With coma
0.000 0.958 0.042
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.960 0.040
E20-E35 Disorders of other endocrine glands
0.000 0.960 0.040
E23 Hypofunction and other disorders of pituitary gland
0.000 0.961 0.039
E14.8 With unspecified complications
0.000 0.962 0.038
E13 Other specified diabetes mellitus
0.000 0.963 0.037
E14.1 With ketoacidosis
0.000 0.964 0.036
E11.2 With renal complications
0.000 0.964 0.036
E83.5 Disorders of calcium metabolism
0.000 0.964 0.036
E14.5 With peripheral circulatory complications
0.000 0.964 0.036
E10.3 With ophthalmic complications
0.000 0.964 0.036
E23.6 Other disorders of pituitary gland
0.000 0.964 0.036
E26 Hyperaldosteronism
0.000 0.965 0.035
E23.2 Diabetes insipidus
0.000 0.965 0.035
E14.7 With multiple complications
0.000 0.965 0.035
E14.2 Withrenal complications
0.000 0.965 0.035
E14.0 With coma
0.000 0.965 0.035
E14.6 With other specified complications
0.000 0.965 0.035
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.965 0.035
E12 Malnutrition-related diabetes mellitus
0.000 0.965 0.035
E14.4 With neurological complications
0.000 0.966 0.034
E10.5 With peripheral circulatory complications
0.000 0.966 0.034
E10.8 With unspecified complications
0.000 0.966 0.033
E10.0 With coma
0.000 0.967 0.033
E11.1 With ketoacidosis
0.000 0.967 0.033
E10.4 With neurological complications
0.000 0.967 0.033
E24 Cushing's syndrome
0.000 0.967 0.033
E26.0 Primary hyperaldosteronism
0.000 0.967 0.033
E50-E64 Other nutritional deficiencies
0.000 0.968 0.032
E11.3 With ophthalmic complications
0.000 0.968 0.032
E29 Testicular dysfunction
0.000 0.968 0.032
E16 Other disorders of pancreatic internal secretion
0.000 0.968 0.032
E70-E90 Metabolic disorders
0.000 0.968 0.032
E11.7 With multiple complications
0.000 0.969 0.031
K90-K93 Other diseases of the digestive system
0.000 0.969 0.031
E55 Vitamin D deficiency
0.000 0.969 0.031
E23.0 Hypopituitarism
0.000 0.969 0.031
E55.9 Vitamin D deficiency, unspecified
0.000 0.969 0.031
E13.9 Without complications
0.000 0.970 0.030
E10.7 With multiple complications
0.000 0.970 0.030
E10.2 With renal complications
0.000 0.970 0.030
E16.2 Hypoglycaemia, unspecified
0.000 0.970 0.030
E23.7 Disorder of pituitary gland, unspecified
0.000 0.970 0.030
E83.3 Disorders of phosphorus metabolism
0.000 0.970 0.029
E10.6 With other specified complications
0.000 0.971 0.029
E10.1 With ketoacidosis
0.000 0.971 0.029
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.971 0.028
E32 Diseases of thymus
0.000 0.971 0.028
E31 Polyglandular dysfunction
0.000 0.971 0.028
E30 Disorders of puberty, not elsewhere classified
0.000 0.971 0.028
E25 Adrenogenital disorders
0.000 0.971 0.028
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.972 0.028
E23.1 Drug-induced hypopituitarism
0.000 0.972 0.028
E22 Hyperfunction of pituitary gland
0.000 0.972 0.028
E34 Other endocrine disorders
0.000 0.972 0.028
E28 Ovarian dysfunction
0.000 0.973 0.027
E13.8 With unspecified complications
0.000 0.973 0.027
E13.7 With multiple complications
0.000 0.973 0.027
E13.6 With other specified complications
0.000 0.973 0.027
E13.5 With peripheral circulatory complications
0.000 0.973 0.027
E13.4 With neurological complications
0.000 0.973 0.027
E13.2 With renal complications
0.000 0.973 0.027
E13.1 With ketoacidosis
0.000 0.973 0.027
E13.0 With coma
0.000 0.973 0.027
E24.9 Cushing's syndrome, unspecified
0.000 0.973 0.027
E20 Hypoparathyroidism
0.000 0.973 0.027
E29.1 Testicular hypofunction
0.000 0.974 0.026
E26.9 Hyperaldosteronism, unspecified
0.000 0.974 0.026
E26.8 Other hyperaldosteronism
0.000 0.974 0.026
E26.1 Secondary hyperaldosteronism
0.000 0.974 0.026
E11.8 With unspecified complications
0.000 0.974 0.025
E24.0 Pituitary-dependent Cushing's disease
0.000 0.975 0.025
E15 Nondiabetic hypoglycaemic coma
0.000 0.975 0.025
E12.9 Without complications
0.000 0.975 0.025
E12.8 With unspecified complications
0.000 0.975 0.025
E12.7 With multiple complications
0.000 0.975 0.025
E12.6 With other specified complications
0.000 0.975 0.025
E12.5 With peripheral circulatory complications
0.000 0.975 0.025
E12.4 With neurological complications
0.000 0.975 0.025
E12.3 With ophthalmic complications
0.000 0.975 0.025
E12.2 With renal complications
0.000 0.975 0.025
E12.1 With ketoacidosis
0.000 0.975 0.025
E12.0 With coma
0.000 0.975 0.025
E40-E46 Malnutrition
0.000 0.975 0.025
E13.3 With ophthalmic complications
0.000 0.975 0.024
K05 Gingivitis and periodontal diseases
0.000 0.976 0.024
E34.9 Endocrine disorder, unspecified
0.000 0.976 0.024
E24.8 Other Cushing's syndrome
0.000 0.976 0.024
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.976 0.024
E24.3 Ectopic ACTH syndrome
0.000 0.976 0.024
E24.2 Drug-induced Cushing's syndrome
0.000 0.976 0.024
E24.1 Nelson's syndrome
0.000 0.976 0.024
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.976 0.023
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.976 0.023
E63 Other nutritional deficiencies
0.000 0.976 0.023
E56 Other vitamin deficiencies
0.000 0.976 0.023
E50 Vitamin A deficiency
0.000 0.976 0.023
E60 Dietary zinc deficiency
0.000 0.976 0.023
E59 Dietary selenium deficiency
0.000 0.976 0.023
E58 Dietary calcium deficiency
0.000 0.976 0.023
E54 Ascorbic acid deficiency
0.000 0.976 0.023
E52 Niacin deficiency [pellagra]
0.000 0.976 0.023
E27 Other disorders of adrenal gland
0.000 0.977 0.023
E29.9 Testicular dysfunction, unspecified
0.000 0.977 0.023
E29.8 Other testicular dysfunction
0.000 0.977 0.023
E29.0 Testicular hyperfunction
0.000 0.977 0.023
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.977 0.023
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.977 0.023
E16.4 Abnormal secretion of gastrin
0.000 0.977 0.023
E16.3 Increased secretion of glucagon
0.000 0.977 0.023
E84 Cystic fibrosis
0.000 0.977 0.023
E77 Disorders of glycoprotein metabolism
0.000 0.977 0.023
E76 Disorders of glycosaminoglycan metabolism
0.000 0.977 0.023
E72 Other disorders of amino-acid metabolism
0.000 0.977 0.023
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.977 0.023
E70 Disorders of aromatic amino-acid metabolism
0.000 0.977 0.023
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.977 0.023
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.977 0.022
E22.1 Hyperprolactinaemia
0.000 0.977 0.023
E55.0 Rickets, active
0.000 0.977 0.022
E65-E68 Obesity and other hyperalimentation
0.000 0.978 0.022
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.978 0.022
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.978 0.022
E51 Thiamine deficiency
0.000 0.979 0.021
Z50.8 Care involving use of rehabilitation procedures
0.000 0.979 0.021
E25.9 Adrenogenital disorder, unspecified
0.000 0.979 0.021
E25.8 Other adrenogenital disorders
0.000 0.979 0.021
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.979 0.021
E30.9 Disorder of puberty, unspecified
0.000 0.979 0.021
E30.8 Other disorders of puberty
0.000 0.979 0.021
E30.1 Precocious puberty
0.000 0.979 0.021
E30.0 Delayed puberty
0.000 0.979 0.021
E31.9 Polyglandular dysfunction, unspecified
0.000 0.979 0.021
E31.8 Other polyglandular dysfunction
0.000 0.979 0.021
E31.1 Polyglandular hyperfunction
0.000 0.979 0.021
E31.0 Autoimmune polyglandular failure
0.000 0.979 0.021
E32.9 Disease of thymus, unspecified
0.000 0.979 0.021
E32.8 Other diseases of thymus
0.000 0.979 0.021
E32.1 Abscess of thymus
0.000 0.979 0.021
E32.0 Persistent hyperplasia of thymus
0.000 0.979 0.021
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.979 0.021
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.979 0.021
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.979 0.021
E79 Disorders of purine and pyrimidine metabolism
0.000 0.979 0.020
E53 Deficiency of other B group vitamins
0.000 0.980 0.020
E16.1 Other hypoglycaemia
0.000 0.980 0.020
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.980 0.020
E22.8 Other hyperfunction of pituitary gland
0.000 0.980 0.020
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.980 0.020
E34.5 Androgen resistance syndrome
0.000 0.980 0.020
E34.4 Constitutional tall stature
0.000 0.980 0.020
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.980 0.020
E34.1 Other hypersecretion of intestinal hormones
0.000 0.980 0.020
K05.1 Chronic gingivitis
0.000 0.980 0.020
E27.1 Primary adrenocortical insufficiency
0.000 0.980 0.020
E85 Amyloidosis
0.000 0.980 0.020
Z50.1 Other physical therapy
0.000 0.980 0.020
E87.2 Acidosis
0.000 0.980 0.020
E28.9 Ovarian dysfunction, unspecified
0.000 0.980 0.020
E28.8 Other ovarian dysfunction
0.000 0.980 0.020
E28.1 Androgen excess
0.000 0.980 0.020
E28.0 Oestrogen excess
0.000 0.980 0.020
E28.3 Primary ovarian failure
0.000 0.980 0.020
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.980 0.019
E74 Other disorders of carbohydrate metabolism
0.000 0.980 0.019
Z50 Care involving use of rehabilitation procedures
0.000 0.981 0.019
E20.8 Other hypoparathyroidism
0.000 0.981 0.019
E20.1 Pseudohypoparathyroidism
0.000 0.981 0.019
E20.0 Idiopathic hypoparathyroidism
0.000 0.981 0.019
E10.9 Without complications
0.000 0.981 0.019
E22.0 Acromegaly and pituitary gigantism
0.000 0.981 0.019
K05.6 Periodontal disease, unspecified
0.000 0.981 0.019
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.981 0.019
E34.0 Carcinoid syndrome
0.000 0.981 0.019
E89.2 Postprocedural hypoparathyroidism
0.000 0.981 0.018
E28.2 Polycystic ovarian syndrome
0.000 0.982 0.018
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.982 0.018
E45 Retarded development following protein-energy malnutrition
0.000 0.982 0.018
E43 Unspecified severe protein-energy malnutrition
0.000 0.982 0.018
E42 Marasmic kwashiorkor
0.000 0.982 0.018
E41 Nutritional marasmus
0.000 0.982 0.018
E40 Kwashiorkor
0.000 0.982 0.018
E11.6 With other specified complications
0.000 0.982 0.018
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.982 0.018
E61 Deficiency of other nutrient elements
0.000 0.982 0.018
E34.8 Other specified endocrine disorders
0.000 0.982 0.018
E27.2 Addisonian crisis
0.000 0.982 0.018
K05.2 Acute periodontitis
0.000 0.982 0.018
K05.5 Other periodontal diseases
0.000 0.982 0.018
K05.4 Periodontosis
0.000 0.982 0.018
E65 Localised adiposity
0.000 0.982 0.018
E20.9 Hypoparathyroidism, unspecified
0.000 0.982 0.017
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.983 0.017
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.983 0.017
E50.9 Vitamin A deficiency, unspecified
0.000 0.983 0.017
E50.8 Other manifestations of vitamin A deficiency
0.000 0.983 0.017
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.983 0.017
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.983 0.017
E50.5 Vitamin A deficiency with night blindness
0.000 0.983 0.017
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.983 0.017
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.983 0.017
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.983 0.017
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.983 0.017
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.983 0.017
E56.9 Vitamin deficiency, unspecified
0.000 0.983 0.017
E56.8 Deficiency of other vitamins
0.000 0.983 0.017
E56.1 Deficiency of vitamin K
0.000 0.983 0.017
E56.0 Deficiency of vitamin E
0.000 0.983 0.017
E63.9 Nutritional deficiency, unspecified
0.000 0.983 0.017
E63.8 Other specified nutritional deficiencies
0.000 0.983 0.017
E63.1 Imbalance of constituents of food intake
0.000 0.983 0.017
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.983 0.017
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.983 0.017
E64.8 Sequelae of other nutritional deficiencies
0.000 0.983 0.017
E64.3 Sequelae of rickets
0.000 0.983 0.017
E64.2 Sequelae of vitamin C deficiency
0.000 0.983 0.017
E64.1 Sequelae of vitamin A deficiency
0.000 0.983 0.017
E64.0 Sequelae of protein-energy malnutrition
0.000 0.983 0.017
E27.5 Adrenomedullary hyperfunction
0.000 0.983 0.017
E27.0 Other adrenocortical overactivity
0.000 0.983 0.017
Z50.5 Speech therapy
0.000 0.983 0.017
E87.3 Alkalosis
0.000 0.983 0.017
E73 Lactose intolerance
0.000 0.983 0.016
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.983 0.017
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.983 0.017
E70.3 Albinism
0.000 0.983 0.017
E70.2 Disorders of tyrosine metabolism
0.000 0.983 0.017
E70.1 Other hyperphenylalaninaemias
0.000 0.983 0.017
E70.0 Classical phenylketonuria
0.000 0.983 0.017
E71.3 Disorders of fatty-acid metabolism
0.000 0.983 0.017
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.983 0.017
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.983 0.017
E71.0 Maple-syrup-urine disease
0.000 0.983 0.017
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.983 0.017
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.983 0.017
E72.5 Disorders of glycine metabolism
0.000 0.983 0.017
E72.4 Disorders of ornithine metabolism
0.000 0.983 0.017
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.983 0.017
E72.2 Disorders of urea cycle metabolism
0.000 0.983 0.017
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.983 0.017
E72.0 Disorders of amino-acid transport
0.000 0.983 0.017
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.983 0.017
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.983 0.017
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.983 0.017
E76.2 Other mucopolysaccharidoses
0.000 0.983 0.017
E76.1 Mucopolysaccharidosis, type II
0.000 0.983 0.017
E76.0 Mucopolysaccharidosis, type I
0.000 0.983 0.017
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.983 0.017
E77.8 Other disorders of glycoprotein metabolism
0.000 0.983 0.017
E77.1 Defects in glycoprotein degradation
0.000 0.983 0.017
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.983 0.017
E84.9 Cystic fibrosis, unspecified
0.000 0.983 0.017
E84.8 Cystic fibrosis with other manifestations
0.000 0.983 0.017
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.983 0.017
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.983 0.017
E88 Other metabolic disorders
0.000 0.983 0.017
E34.3 Short stature, not elsewhere classified
0.000 0.983 0.016
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.983 0.016
K93.1 Megacolon in Chagas' disease
0.000 0.983 0.016
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.983 0.016
Z50.4 Psychotherapy, not elsewhere classified
0.000 0.984 0.016
E85.9 Amyloidosis, unspecified
0.000 0.984 0.016
E67 Other hyperalimentation
0.000 0.984 0.016
E68 Sequelae of hyperalimentation
0.000 0.984 0.016
Z50.0 Cardiac rehabilitation
0.000 0.984 0.016
E89.4 Postprocedural ovarian failure
0.000 0.984 0.016
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.000 0.984 0.016
E75.6 Lipid storage disorder, unspecified
0.000 0.984 0.016
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.984 0.016
E75.3 Sphingolipidosis, unspecified
0.000 0.984 0.016
E75.2 Other sphingolipidosis
0.000 0.984 0.016
E75.1 Other gangliosidosis
0.000 0.984 0.016
E75.0 GM2 gangliosidosis
0.000 0.984 0.016
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.984 0.016
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.984 0.016
E89.5 Postprocedural testicular hypofunction
0.000 0.984 0.016
E89.1 Postprocedural hypoinsulinaemia
0.000 0.984 0.016
E51.9 Thiamine deficiency, unspecified
0.000 0.984 0.015
E51.8 Other manifestations of thiamine deficiency
0.000 0.984 0.015
E51.1 Beriberi
0.000 0.984 0.015
K05.0 Acute gingivitis
0.000 0.984 0.015
E80.2 Other porphyria
0.000 0.985 0.015
E21.0 Primary hyperparathyroidism
0.000 0.985 0.015
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.985 0.015
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.985 0.015
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.985 0.015
E79.1 Lesch-Nyhan syndrome
0.000 0.985 0.015
E53.1 Pyridoxine deficiency
0.000 0.985 0.015
E53.0 Riboflavin deficiency
0.000 0.985 0.015
E75.5 Other lipid storage disorders
0.000 0.985 0.015
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.985 0.015
E80.5 Crigler-Najjar syndrome
0.000 0.985 0.015
E80.3 Defects of catalase and peroxydase
0.000 0.985 0.015
E80.0 Hereditary erythropoietic porphyria
0.000 0.985 0.015
E53.8 Deficiency of other specified B group vitamins
0.000 0.985 0.015
E80.1 Porphyria cutanea tarda
0.000 0.985 0.015
E85.8 Other amyloidosis
0.000 0.985 0.014
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.985 0.014
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.985 0.014
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.985 0.014
E46 Unspecified protein-energy malnutrition
0.000 0.985 0.015
E21.4 Other specified disorders of parathyroid gland
0.000 0.986 0.014
E21.2 Other hyperparathyroidism
0.000 0.986 0.014
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.986 0.014
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.986 0.014
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.986 0.014
E74.2 Disorders of galactose metabolism
0.000 0.986 0.014
E74.1 Disorders of fructose metabolism
0.000 0.986 0.014
E74.0 Glycogen storage disease
0.000 0.986 0.014
Z50.6 Orthoptic training
0.000 0.986 0.014
E87.4 Mixed disorder of acid-base balance
0.000 0.986 0.014
E87.0 Hyperosmolality and hypernatraemia
0.000 0.986 0.014
E80.4 Gilbert's syndrome
0.000 0.986 0.014
E51.2 Wernicke's encephalopathy
0.000 0.986 0.013
E44.1 Mild protein-energy malnutrition
0.000 0.987 0.013
E44.0 Moderate protein-energy malnutrition
0.000 0.987 0.013
E88.2 Lipomatosis, not elsewhere classified
0.000 0.987 0.013
E61.9 Deficiency of nutrient element, unspecified
0.000 0.987 0.013
E61.8 Deficiency of other specified nutrient elements
0.000 0.987 0.013
E61.7 Deficiency of multiple nutrient elements
0.000 0.987 0.013
E61.6 Vanadium deficiency
0.000 0.987 0.013
E61.5 Molybdenum deficiency
0.000 0.987 0.013
E61.4 Chromium deficiency
0.000 0.987 0.013
E61.3 Manganese deficiency
0.000 0.987 0.013
E61.0 Copper deficiency
0.000 0.987 0.013
E83.4 Disorders of magnesium metabolism
0.001 0.987 0.013
E80.6 Other disorders of bilirubin metabolism
0.000 0.987 0.013
K05.22 Aggressive periodontitis, generalized
0.000 0.987 0.013
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.987 0.013
E61.2 Magnesium deficiency
0.000 0.987 0.013
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.987 0.012
E89.0 Postprocedural hypothyroidism
0.000 0.988 0.012
E27.8 Other specified disorders of adrenal gland
0.000 0.988 0.012
E73.8 Other lactose intolerance
0.000 0.988 0.012
E73.1 Secondary lactase deficiency
0.000 0.988 0.012
E73.0 Congenital lactase deficiency
0.000 0.988 0.012
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.988 0.012
R31 Unspecified haematuria
0.012 0.988 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.988 0.012
E88.8 Other specified metabolic disorders
0.000 0.988 0.012
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.988 0.012
Z50.2 Alcohol rehabilitation
0.000 0.988 0.012
E85.3 Secondary systemic amyloidosis
0.000 0.988 0.012
E85.4 Organ-limited amyloidosis
0.000 0.988 0.012
E27.9 Disorder of adrenal gland, unspecified
0.000 0.988 0.012
E67.8 Other specified hyperalimentation
0.000 0.988 0.012
E67.3 Hypervitaminosis D
0.000 0.988 0.012
E67.2 Megavitamin-B6 syndrome
0.000 0.988 0.012
E67.1 Hypercarotenaemia
0.000 0.988 0.012
E67.0 Hypervitaminosis A
0.000 0.988 0.012
E53.9 Vitamin B deficiency, unspecified
0.000 0.988 0.012
I42.0 Dilated cardiomyopathy
0.012 0.988 0.000
Z50.3 Drug rehabilitation
0.000 0.989 0.011
E87.7 Fluid overload
0.000 0.989 0.011
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.989 0.011
E87.5 Hyperkalaemia
0.000 0.989 0.011
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.989 0.010
E89.3 Postprocedural hypopituitarism
0.000 0.989 0.010
E88.3 Tumour lysis syndrome
0.000 0.990 0.010
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.009 0.991 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.991 0.009
E61.1 Iron deficiency
0.000 0.991 0.009
E00-E07 Disorders of thyroid gland
0.000 0.991 0.009
R90.0 Intracranial space-occupying lesion
0.008 0.992 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.008 0.992 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.008 0.992 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.008 0.992 0.000
E11.4 With neurological complications
0.000 0.992 0.008
I42.1 Obstructive hypertrophic cardiomyopathy
0.008 0.992 0.000
T43.2 Other and unspecified antidepressants
0.007 0.993 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.007 0.993 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.993 0.007
I42 Cardiomyopathy
0.007 0.993 0.000
E07 Other disorders of thyroid
0.000 0.993 0.007
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.993 0.006
E00 Congenital iodine-deficiency syndrome
0.000 0.993 0.006
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.006 0.994 0.000
E73.9 Lactose intolerance, unspecified
0.001 0.994 0.005
T39.0 Salicylates
0.006 0.994 0.000
E66 Obesity
0.000 0.994 0.006
T39.1 4-Aminophenol derivatives
0.006 0.994 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.006 0.994 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.006 0.994 0.000
T43.9 Psychotropic drug, unspecified
0.006 0.994 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.006 0.994 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.006 0.994 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.000 0.994 0.006
T43.5 Other and unspecified antipsychotics and neuroleptics
0.006 0.994 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.994 0.006
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.005 0.994 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.994 0.005
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.994 0.005
T43.4 Butyrophenone and thioxanthene neuroleptics
0.005 0.995 0.000
Z93.2 Ileostomy status
0.005 0.995 0.000
E03 Other hypothyroidism
0.000 0.995 0.005
T39.4 Antirheumatics, not elsewhere classified
0.005 0.995 0.000
T39.2 Pyrazolone derivatives
0.005 0.995 0.000
E07.8 Other specified disorders of thyroid
0.000 0.995 0.005
I42.2 Other hypertrophic cardiomyopathy
0.005 0.995 0.000
T43.6 Psychostimulants with abuse potential
0.005 0.995 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.005 0.995 0.000
I42.5 Other restrictive cardiomyopathy
0.005 0.995 0.000
I42.4 Endocardial fibroelastosis
0.005 0.995 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.005 0.995 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.005 0.995 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.995 0.005
E07.1 Dyshormogenetic goitre
0.000 0.995 0.005
E07.0 Hypersecretion of calcitonin
0.000 0.995 0.005
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.005 0.995 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.995 0.005
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.995 0.005
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.995 0.005
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.995 0.005
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.995 0.005
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.995 0.005
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.995 0.005
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.995 0.005
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.995 0.005
E04 Other non-toxic goitre
0.000 0.995 0.005
E07.9 Disorder of thyroid, unspecified
0.000 0.995 0.005
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.005 0.995 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.005 0.995 0.000
E66.1 Drug-induced obesity
0.000 0.995 0.005
T36 Poisoning by systemic antibiotics
0.005 0.995 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.005 0.995 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.005 0.995 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.005 0.995 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.005 0.995 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.005 0.995 0.000
N48.1 Balanoposthitis
0.005 0.995 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.004 0.995 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.995 0.005
E66.0 Obesity due to excess calories
0.000 0.995 0.004
I42.8 Other cardiomyopathies
0.004 0.996 0.000
I42.6 Alcoholic cardiomyopathy
0.004 0.996 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.004 0.996 0.000
E05.5 Thyroid crisis or storm
0.000 0.996 0.004
E05.4 Thyrotoxicosis factitia
0.000 0.996 0.004
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.996 0.004
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.996 0.004
T42.4 Benzodiazepines
0.004 0.996 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.996 0.004
H59.8 Other postprocedural disorders of eye and adnexa
0.004 0.996 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.004 0.996 0.000
E03.5 Myxoedema coma
0.000 0.996 0.004
E03.4 Atrophy of thyroid (acquired)
0.000 0.996 0.004
E03.3 Postinfectious hypothyroidism
0.000 0.996 0.004
E03.1 Congenital hypothyroidism without goitre
0.000 0.996 0.004
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.996 0.004
G35 Multiple sclerosis
0.000 0.996 0.004
T40.2 Other opioids
0.004 0.996 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.004 0.996 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.004 0.996 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.004 0.996 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.004 0.996 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.004 0.996 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.004 0.996 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.004 0.996 0.000
T44.0 Anticholinesterase agents
0.004 0.996 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.004 0.996 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.004 0.996 0.000
T47.7 Emetics
0.004 0.996 0.000
T47.6 Antidiarrhoeal drugs
0.004 0.996 0.000
T47.5 Digestants
0.004 0.996 0.000
T47.4 Other laxatives
0.004 0.996 0.000
T47.3 Saline and osmotic laxatives
0.004 0.996 0.000
T47.2 Stimulant laxatives
0.004 0.996 0.000
T47.0 Histamine H(2)-receptor antagonists
0.004 0.996 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.000 0.996 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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