TreeWAS – Variant ID: rs2235302

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D68.2 Hereditary deficiency of other clotting factors	0.993	0.007	0.000
D68 Other coagulation defects	0.413	0.587	0.000
D68.1 Hereditary factor XI deficiency	0.324	0.676	0.000
D68.6 Other Thrombophilia	0.312	0.688	0.000
D68.5 Primary Thrombophilia	0.300	0.700	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.287	0.713	0.000
D68.0 Von Willebrand's disease	0.277	0.723	0.000
D68.4 Acquired coagulation factor deficiency	0.276	0.724	0.000
D68.8 Other specified coagulation defects	0.271	0.729	0.000
D68.9 Coagulation defect, unspecified	0.250	0.750	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.149	0.851	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.114	0.886	0.000
D67 Hereditary factor IX deficiency	0.108	0.892	0.000
D66 Hereditary factor VIII deficiency	0.105	0.895	0.000
D69 Purpura and other haemorrhagic conditions	0.073	0.927	0.000
D69.2 Other nonthrombocytopenic purpura	0.059	0.941	0.000
D69.8 Other specified haemorrhagic conditions	0.059	0.941	0.000
D69.0 Allergic purpura	0.059	0.941	0.000
D69.9 Haemorrhagic condition, unspecified	0.056	0.944	0.000
D69.5 Secondary thrombocytopenia	0.056	0.944	0.000
D69.1 Qualitative platelet defects	0.051	0.949	0.000
D69.4 Other primary thrombocytopenia	0.048	0.952	0.000
N30.9 Cystitis, unspecified	0.000	0.970	0.030
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.026	0.974	0.000
D55-D59 Haemolytic anaemias	0.023	0.977	0.000
D80-D89 Certain disorders involving the immune mechanism	0.023	0.977	0.000
D86 Sarcoidosis	0.020	0.980	0.000
D59 Acquired haemolytic anaemia	0.020	0.980	0.000
D58 Other hereditary haemolytic anaemias	0.020	0.980	0.000
D83 Common variable immunodeficiency	0.019	0.981	0.000
D59.1 Other autoimmune haemolytic anaemias	0.019	0.981	0.000
K51.9 Ulcerative colitis, unspecified	0.018	0.982	0.000
D80 Immunodeficiency with predominantly antibody defects	0.017	0.983	0.000
D86.0 Sarcoidosis of lung	0.017	0.983	0.000
D55 Anaemia due to enzyme disorders	0.017	0.983	0.000
D58.0 Hereditary spherocytosis	0.017	0.983	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.017	0.983	0.000
D57 Sickle-cell disorders	0.017	0.983	0.000
D86.8 Sarcoidosis of other and combined sites	0.017	0.983	0.000
D56 Thalassaemia	0.017	0.983	0.000
D84 Other immunodeficiencies	0.016	0.983	0.000
D81 Combined immunodeficiencies	0.016	0.983	0.000
D86.3 Sarcoidosis of skin	0.016	0.984	0.000
D82 Immunodeficiency associated with other major defects	0.016	0.984	0.000
D86.1 Sarcoidosis of lymph nodes	0.016	0.984	0.000
D83.9 Common variable immunodeficiency, unspecified	0.016	0.984	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.015	0.985	0.000
D58.2 Other haemoglobinopathies	0.014	0.985	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.014	0.985	0.000
D59.8 Other acquired haemolytic anaemias	0.014	0.985	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.014	0.985	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.014	0.985	0.000
D59.3 Haemolytic-uraemic syndrome	0.014	0.985	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.014	0.985	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.014	0.985	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.014	0.986	0.000
D58.1 Hereditary elliptocytosis	0.014	0.986	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.014	0.986	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.014	0.986	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.986	0.014
D83.8 Other common variable immunodeficiencies	0.013	0.986	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.013	0.986	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.013	0.986	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.013	0.986	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.013	0.987	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.013	0.987	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.013	0.987	0.000
D73 Diseases of spleen	0.013	0.987	0.000
D86.9 Sarcoidosis, unspecified	0.013	0.987	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.013	0.987	0.000
D84.9 Immunodeficiency, unspecified	0.013	0.987	0.000
D56.1 Beta thalassaemia	0.013	0.987	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.013	0.987	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.013	0.987	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.013	0.987	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.013	0.987	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.013	0.987	0.000
D84.1 Defects in the complement system	0.013	0.987	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.012	0.987	0.000
D73.0 Hyposplenism	0.013	0.987	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.012	0.987	0.000
D55.8 Other anaemias due to enzyme disorders	0.012	0.987	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.012	0.987	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.012	0.987	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.012	0.987	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.012	0.987	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.012	0.988	0.000
D57.8 Other sickle-cell disorders	0.012	0.988	0.000
D57.3 Sickle-cell trait	0.012	0.988	0.000
D57.2 Double heterozygous sickling disorders	0.012	0.988	0.000
D57.0 Sickle-cell anaemia with crisis	0.012	0.988	0.000
D56.9 Thalassaemia, unspecified	0.012	0.988	0.000
D56.8 Other thalassaemias	0.012	0.988	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.012	0.988	0.000
D56.2 Delta-beta thalassaemia	0.012	0.988	0.000
D56.0 Alpha thalassaemia	0.012	0.988	0.000
D81.9 Combined immunodeficiency, unspecified	0.012	0.988	0.000
D81.8 Other combined immunodeficiencies	0.012	0.988	0.000
D81.7 Major histocompatibility complex class II deficiency	0.012	0.988	0.000
D81.6 Major histocompatibility complex class I deficiency	0.012	0.988	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.012	0.988	0.000
D81.4 Nezelof's syndrome	0.012	0.988	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.012	0.988	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.012	0.988	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.012	0.988	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.012	0.988	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.012	0.988	0.000
D57.1 Sickle-cell anaemia without crisis	0.012	0.988	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.012	0.988	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.012	0.988	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.012	0.988	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.012	0.988	0.000
D82.2 Immunodeficiency with short-limbed stature	0.012	0.988	0.000
D82.0 Wiskott-Aldrich syndrome	0.012	0.988	0.000
D82.1 Di George's syndrome	0.011	0.988	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.010	0.988	0.001
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.011	0.989	0.000
D73.3 Abscess of spleen	0.011	0.989	0.000
D56.3 Thalassaemia trait	0.011	0.989	0.000
D73.5 Infarction of spleen	0.011	0.989	0.000
D84.8 Other specified immunodeficiencies	0.010	0.990	0.000
D73.4 Cyst of spleen	0.010	0.990	0.000
K51 Ulcerative colitis	0.010	0.990	0.000
D74 Methaemoglobinaemia	0.010	0.990	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.010	0.990	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.010	0.990	0.000
K51.8 Other ulcerative colitis	0.010	0.990	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.009	0.990	0.001
D73.2 Chronic congestive splenomegaly	0.010	0.990	0.000
D75 Other diseases of blood and blood-forming organs	0.010	0.990	0.000
I42.0 Dilated cardiomyopathy	0.009	0.991	0.000
H92.1 Otorrhoea	0.009	0.991	0.000
D73.1 Hypersplenism	0.009	0.991	0.000
F33 Recurrent depressive disorder	0.000	0.991	0.009
D73.8 Other diseases of spleen	0.009	0.991	0.000
D89.3 Immune reconstitution syndrome	0.007	0.991	0.001
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.008	0.992	0.000
G47.9 Sleep disorder, unspecified	0.000	0.992	0.008
I42.9 Cardiomyopathy, unspecified	0.008	0.992	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.007	0.992	0.001
K51.4 Pseudopolyposis of colon	0.008	0.992	0.000
D73.9 Disease of spleen, unspecified	0.008	0.992	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.008	0.992	0.000
D75.2 Essential thrombocytosis	0.008	0.992	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.008	0.992	0.000
D89.1 Cryoglobulinaemia	0.007	0.992	0.001
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.992	0.008
K51.1 Ulcerative (chronic) ileocolitis	0.008	0.992	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.006	0.992	0.001
D74.9 Methaemoglobinaemia, unspecified	0.007	0.993	0.000
D74.8 Other methaemoglobinaemias	0.007	0.993	0.000
D74.0 Congenital methaemoglobinaemia	0.007	0.993	0.000
I42 Cardiomyopathy	0.007	0.993	0.000
K51.2 Ulcerative (chronic) proctitis	0.007	0.993	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.007	0.993	0.000
D75.0 Familial erythrocytosis	0.007	0.993	0.000
I27.2 Other secondary pulmonary hypertension	0.007	0.993	0.000
D50-D53 Nutritional anaemias	0.007	0.993	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.993	0.007
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.993	0.007
F33.8 Other recurrent depressive disorders	0.000	0.993	0.006
S05.8 Other injuries of eye and orbit	0.007	0.993	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.006	0.993	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.994	0.006
D76.2 Haemophagocytic syndrome, infection-associated	0.006	0.994	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.006	0.994	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.006	0.994	0.000
C50.4 Upper-outer quadrant of breast	0.000	0.994	0.006
D72 Other disorders of white blood cells	0.006	0.994	0.000
S05.9 Injury of eye and orbit, part unspecified	0.006	0.994	0.000
S05 Injury of eye and orbit	0.006	0.994	0.000
I27.0 Primary pulmonary hypertension	0.006	0.994	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.994	0.006
I42.5 Other restrictive cardiomyopathy	0.005	0.994	0.000
I42.4 Endocardial fibroelastosis	0.005	0.994	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.005	0.994	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.994	0.006
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.995	0.005
I42.7 Cardiomyopathy due to drugs and other external agents	0.005	0.995	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.005	0.995	0.000
I27 Other pulmonary heart diseases	0.005	0.995	0.000
D69.6 Thrombocytopenia, unspecified	0.005	0.995	0.000
S05.1 Contusion of eyeball and orbital tissues	0.005	0.995	0.000
D60-D64 Aplastic and other anaemias	0.005	0.995	0.000
H65.4 Other chronic nonsuppurative otitis media	0.005	0.995	0.000
D76.3 Other histiocytosis syndromes	0.005	0.995	0.000
D53 Other nutritional anaemias	0.005	0.995	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.005	0.995	0.000
D72.9 Disorder of white blood cells, unspecified	0.005	0.995	0.000
D72.0 Genetic anomalies of leukocytes	0.005	0.995	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.001	0.995	0.004
K26.5 Chronic or unspecified with perforation	0.000	0.995	0.005
I42.2 Other hypertrophic cardiomyopathy	0.005	0.995	0.000
I42.6 Alcoholic cardiomyopathy	0.004	0.995	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.995	0.005
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.004	0.995	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.004	0.996	0.000
S05.7 Avulsion of eye	0.004	0.996	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.004	0.996	0.000
D75.1 Secondary polycythaemia	0.004	0.996	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.004	0.996	0.000
F32.1 Moderate depressive episode	0.000	0.996	0.004
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.004	0.996	0.000
I27.1 Kyphoscoliotic heart disease	0.004	0.996	0.000
D72.1 Eosinophilia	0.004	0.996	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.004	0.996	0.000
Y44.2 Anticoagulants	0.004	0.996	0.000
D52 Folate deficiency anaemia	0.004	0.996	0.000
I27.8 Other specified pulmonary heart diseases	0.004	0.996	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.996	0.004
D51 Vitamin B12 deficiency anaemia	0.004	0.996	0.000
D53.8 Other specified nutritional anaemias	0.004	0.996	0.000
D53.2 Scorbutic anaemia	0.004	0.996	0.000
D53.0 Protein deficiency anaemia	0.004	0.996	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.996	0.004
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.003	0.996	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.004	0.996	0.000
D53.9 Nutritional anaemia, unspecified	0.003	0.996	0.000
M85.8 Other specified disorders of bone density and structure	0.000	0.996	0.004
K51.5 Mucosal proctocolitis	0.003	0.996	0.001
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.996	0.004
F30-F39 Mood [affective] disorders	0.000	0.997	0.003
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.003	0.997	0.000
D22.0 Melanocytic naevi of lip	0.003	0.997	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.997	0.003
N30.2 Other chronic cystitis	0.000	0.997	0.003
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.003	0.997	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.003	0.997	0.000
I42.8 Other cardiomyopathies	0.003	0.997	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.997	0.003
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.003	0.997	0.000
I27.9 Pulmonary heart disease, unspecified	0.003	0.997	0.000
F32 Depressive episode	0.000	0.997	0.003
D63 Anaemia in chronic diseases classified elsewhere	0.003	0.997	0.000
D60.8 Other acquired pure red cell aplasias	0.003	0.997	0.000
D60.1 Transient acquired pure red cell aplasia	0.003	0.997	0.000
D60.0 Chronic acquired pure red cell aplasia	0.003	0.997	0.000
H92 Otalgia and effusion of ear	0.003	0.997	0.000
D52.8 Other folate deficiency anaemias	0.003	0.997	0.000
D52.1 Drug-induced folate deficiency anaemia	0.003	0.997	0.000
D52.0 Dietary folate deficiency anaemia	0.003	0.997	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.003	0.997	0.000
D51.2 Transcobalamin II deficiency	0.003	0.997	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.003	0.997	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.003	0.997	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.997	0.003
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
F32.0 Mild depressive episode	0.000	0.997	0.003
D63.0 Anaemia in neoplastic disease	0.003	0.997	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.003	0.997	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.997	0.003
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.997	0.003
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.997	0.003
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.997	0.003
D51.3 Other dietary vitamin B12 deficiency anaemia	0.003	0.997	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.003	0.997	0.000
F38 Other mood [affective] disorders	0.000	0.997	0.003
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.997	0.003
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
R85.5 Abnormal microbiological findings	0.000	0.997	0.003
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.997	0.003
F39 Unspecified mood [affective] disorder	0.000	0.997	0.003
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.003	0.997	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.997	0.003
H92.2 Otorrhagia	0.003	0.997	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.997	0.003
O66 Other obstructed labour	0.000	0.997	0.003
D61 Other aplastic anaemias	0.003	0.997	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.002	0.997	0.000
F34 Persistent mood [affective] disorders	0.000	0.997	0.002
U51 Admission status on psychiatric patients	0.000	0.997	0.002
D10.3 Other and unspecified parts of mouth	0.000	0.997	0.003
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
N30 Cystitis	0.000	0.998	0.002
K50-K52 Noninfective enteritis and colitis	0.002	0.998	0.000
F30 Manic episode	0.000	0.998	0.002
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
N34.2 Other urethritis	0.002	0.998	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.998	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
S30.1 Contusion of abdominal wall	0.002	0.998	0.000
F32.8 Other depressive episodes	0.000	0.998	0.002
F38.8 Other specified mood [affective] disorders	0.000	0.998	0.002
F38.1 Other recurrent mood [affective] disorders	0.000	0.998	0.002
F38.0 Other single mood [affective] disorders	0.000	0.998	0.002
K61.3 Ischiorectal abscess	0.002	0.998	0.000
O66.2 Obstructed labour due to unusually large foetus	0.000	0.998	0.002
D64 Other anaemias	0.002	0.998	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.998	0.002
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.998	0.002
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
Y51.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
Y51.0 Anticholinesterase agents	0.000	0.998	0.002
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
Z40.8 Other prophylactic surgery	0.002	0.998	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
F31 Bipolar affective disorder	0.000	0.998	0.002
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.000	0.998	0.002
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.998	0.002
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
Z63.4 Disappearance and death of family member	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
O66.8 Other specified obstructed labour	0.000	0.998	0.002
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.998	0.002
O66.1 Obstructed labour due to locked twins	0.000	0.998	0.002
C15.5 Lower third of oesophagus	0.000	0.998	0.002
D61.8 Other specified aplastic anaemias	0.002	0.998	0.000
D61.3 Idiopathic aplastic anaemia	0.002	0.998	0.000
D61.2 Aplastic anaemia due to other external agents	0.002	0.998	0.000
S30.2 Contusion of external genital organs	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
F30.0 Hypomania	0.000	0.998	0.002
H20.8 Other iridocyclitis	0.000	0.998	0.002
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.998	0.002
F34.8 Other persistent mood [affective] disorders	0.000	0.998	0.002
F34.0 Cyclothymia	0.000	0.998	0.002
U51.2 Previously admitted to a psychiatric hospital of another provider	0.000	0.998	0.002
O66.4 Failed trial of labour, unspecified	0.000	0.998	0.002
D64.0 Hereditary sideroblastic anaemia	0.002	0.998	0.000
D50.1 Sideropenic dysphagia	0.002	0.998	0.000
J99.0 Rheumatoid lung disease	0.002	0.998	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
O66.9 Obstructed labour, unspecified	0.000	0.998	0.002
Z40 Prophylactic surgery	0.002	0.998	0.000
F30.8 Other manic episodes	0.000	0.998	0.002
C02.9 Tongue, unspecified	0.000	0.998	0.002
D50 Iron deficiency anaemia	0.002	0.998	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
J99 Respiratory disorders in diseases classified elsewhere	0.002	0.998	0.000
D61.0 Constitutional aplastic anaemia	0.002	0.998	0.000
U81.0 Vancomycin resistant agent	0.000	0.998	0.002
D64.4 Congenital dyserythropoietic anaemia	0.002	0.998	0.000
D64.3 Other sideroblastic anaemias	0.002	0.998	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.002	0.998	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.000	0.998	0.002
R82.9 Other and unspecified abnormal finding in urine	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.000	0.998	0.002
D61.1 Drug-induced aplastic anaemia	0.002	0.998	0.000
D12.7 Rectosigmoid junction	0.000	0.998	0.002
M85.9 Disorder of bone density and structure, unspecified	0.000	0.998	0.002
U81 Agent resistant to vancomycin and related antibiotics	0.000	0.998	0.002
D52.9 Folate deficiency anaemia, unspecified	0.002	0.998	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.998	0.002
F30.1 Mania without psychotic symptoms	0.000	0.998	0.002
F34.1 Dysthymia	0.000	0.998	0.002
N30.0 Acute cystitis	0.000	0.998	0.002
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
N02.9 Unspecified	0.002	0.998	0.000
K50 Crohn's disease [regional enteritis]	0.002	0.998	0.000
C09.9 Tonsil, unspecified	0.000	0.998	0.002
D64.8 Other specified anaemias	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.998	0.002
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
Z40.9 Prophylactic surgery, unspecified	0.002	0.998	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.998	0.002
F31.8 Other bipolar affective disorders	0.000	0.998	0.002
S30 Superficial injury of abdomen, lower back and pelvis	0.002	0.998	0.000
H92.0 Otalgia	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
I28 Other diseases of pulmonary vessels	0.002	0.998	0.000
E06.3 Autoimmune thyroiditis	0.002	0.998	0.000
I28.8 Other specified diseases of pulmonary vessels	0.002	0.998	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.998	0.002
M85.98 Disorder of bone density and structure, unspecified (Other)	0.000	0.998	0.001
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.000	0.998	0.001
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.000	0.998	0.001
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.000	0.998	0.001
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.000	0.998	0.001
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.000	0.998	0.001
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.000	0.998	0.001
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.000	0.998	0.001
L98.8 Other specified disorders of skin and subcutaneous tissue	0.002	0.998	0.000
S81.0 Open wound of knee	0.002	0.998	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.000	0.998	0.001
F30.2 Mania with psychotic symptoms	0.000	0.998	0.001
M85 Other disorders of bone density and structure	0.000	0.998	0.002
U50 Level of care administered to neonates	0.000	0.998	0.001
U07 Emergency use of U07	0.000	0.998	0.001
U06 Emergency use of U06	0.000	0.998	0.001
U04 Severe acute respiratory syndrome [SARS]	0.000	0.998	0.001
U52 First in a series of a regular day/night admissions	0.000	0.998	0.001
Q04.6 Congenital cerebral cysts	0.001	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.998	0.000
K52.3 Indeterminate colitis	0.002	0.998	0.000
N30.4 Irradiation cystitis	0.000	0.998	0.001
D61.9 Aplastic anaemia, unspecified	0.001	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.001
O62.2 Other uterine inertia	0.001	0.998	0.000
S61.1 Open wound of finger(s) with damage to nail	0.000	0.998	0.001
E28.2 Polycystic ovarian syndrome	0.001	0.999	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.999	0.001
R82.7 Abnormal findings on microbiological examination of urine	0.001	0.999	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.999	0.001
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.999	0.001
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.999	0.000
I28.1 Aneurysm of pulmonary artery	0.001	0.999	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.999	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.001	0.999	0.000
S31.0 Open wound of lower back and pelvis	0.001	0.999	0.000
U80 Agent resistant to penicillin and related antibiotics	0.000	0.999	0.001
S27.1 Traumatic haemothorax	0.000	0.999	0.001
Z56.6 Other physical and mental strain related to work	0.001	0.999	0.000
I86.1 Scrotal varices	0.001	0.999	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.001	0.999	0.000
I74 Arterial embolism and thrombosis	0.000	0.999	0.001
I74.5 Embolism and thrombosis of iliac artery	0.000	0.999	0.001
X23.0 Home	0.000	0.999	0.001
Z30.1 Insertion of (intra-uterine) contraceptive device	0.000	0.999	0.001
Z56.3 Stressful work schedule	0.001	0.999	0.000
K50.9 Crohn's disease, unspecified	0.001	0.999	0.000
K50.8 Other Crohn's disease	0.001	0.999	0.000
M85.5 Aneurysmal bone cyst	0.000	0.999	0.001
M85.3 Osteitis condensans	0.000	0.999	0.001
M85.1 Skeletal fluorosis	0.000	0.999	0.001
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.000	0.999	0.001
U06.9 Emergency use of U06.9	0.000	0.999	0.001
U06.8 Emergency use of U06.8	0.000	0.999	0.001
U06.7 Emergency use of U06.7	0.000	0.999	0.001
U06.6 Emergency use of U06.6	0.000	0.999	0.001
U06.5 Emergency use of U06.5	0.000	0.999	0.001
U06.4 Emergency use of U06.4	0.000	0.999	0.001
U06.3 Emergency use of U06.3	0.000	0.999	0.001
U06.2 Emergency use of U06.2	0.000	0.999	0.001
U06.1 Emergency use of U06.1	0.000	0.999	0.001
U06.0 Emergency use of U06.0	0.000	0.999	0.001
U07.9 Emergency use of U07.9	0.000	0.999	0.001
U07.8 Emergency use of U07.8	0.000	0.999	0.001
U07.7 Emergency use of U07.7	0.000	0.999	0.001
U07.6 Emergency use of U07.6	0.000	0.999	0.001
U07.5 Emergency use of U07.5	0.000	0.999	0.001
U07.4 Emergency use of U07.4	0.000	0.999	0.001
U07.3 Emergency use of U07.3	0.000	0.999	0.001
U07.2 Emergency use of U07.2	0.000	0.999	0.001
U07.1 Emergency use of U07.1	0.000	0.999	0.001
U07.0 Emergency use of U07.0	0.000	0.999	0.001
U50.9 Inquest Adjourned Death	0.000	0.999	0.001
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.000	0.999	0.001
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.000	0.999	0.001
U50.1 Level of care administered to neonates (Special Care)	0.000	0.999	0.001
U50.0 Level of care administered to neonates (Normal Care)	0.000	0.999	0.001
S32.30 Fracture of ilium (closed)	0.001	0.999	0.000
M93.9 Osteochondropathy, unspecified	0.001	0.999	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.999	0.001
K50.1 Crohn's disease of large intestine	0.001	0.999	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.001	0.999	0.000
M85.2 Hyperostosis of skull	0.000	0.999	0.001
R82.1 Myoglobinuria	0.001	0.999	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.999	0.001
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.999	0.001
Y44 Agents primarily affecting blood constituents	0.001	0.999	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.999	0.001
N34.3 Urethral syndrome, unspecified	0.001	0.999	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.999	0.001
R82 Other abnormal findings in urine	0.001	0.999	0.000
Q55.6 Other congenital malformations of penis	0.001	0.999	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.999	0.001
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.999	0.001
M85.19 Skeletal fluorosis (Site unspecified)	0.000	0.999	0.001
M85.18 Skeletal fluorosis (Other)	0.000	0.999	0.001
M85.17 Skeletal fluorosis (Ankle and foot)	0.000	0.999	0.001
M85.16 Skeletal fluorosis (Lower leg)	0.000	0.999	0.001
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.000	0.999	0.001
M85.14 Skeletal fluorosis (Hand)	0.000	0.999	0.001
M85.13 Skeletal fluorosis (Forearm)	0.000	0.999	0.001
M85.12 Skeletal fluorosis (Upper arm)	0.000	0.999	0.001
M85.11 Skeletal fluorosis (Shoulder region)	0.000	0.999	0.001
M85.10 Skeletal fluorosis (Multiple sites)	0.000	0.999	0.001
M85.39 Osteitis condensans (Site unspecified)	0.000	0.999	0.001
M85.38 Osteitis condensans (Other)	0.000	0.999	0.001
M85.37 Osteitis condensans (Ankle and foot)	0.000	0.999	0.001
M85.36 Osteitis condensans (Lower leg)	0.000	0.999	0.001
M85.35 Osteitis condensans (Pelvic region and thigh)	0.000	0.999	0.001
M85.34 Osteitis condensans (Hand)	0.000	0.999	0.001
M85.33 Osteitis condensans (Forearm)	0.000	0.999	0.001
M85.32 Osteitis condensans (Upper arm)	0.000	0.999	0.001
M85.31 Osteitis condensans (Shoulder region)	0.000	0.999	0.001
M85.30 Osteitis condensans (Multiple sites)	0.000	0.999	0.001
M85.59 Aneurysmal bone cyst (Site unspecified)	0.000	0.999	0.001
M85.58 Aneurysmal bone cyst (Other)	0.000	0.999	0.001
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.000	0.999	0.001
M85.56 Aneurysmal bone cyst (Lower leg)	0.000	0.999	0.001
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations