TreeWAS – Variant ID: rs2239527

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M45 Ankylosing spondylitis	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
M45-M49 Spondylopathies	0.999	0.001	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.998	0.002	0.000
K90 Intestinal malabsorption	0.998	0.002	0.000
E14 Unspecified diabetes mellitus	0.997	0.003	0.000
Chapter XI Diseases of the digestive system	0.996	0.004	0.000
K90-K93 Other diseases of the digestive system	0.995	0.005	0.000
K60.2 Anal fissure, unspecified	0.995	0.005	0.000
M35 Other systemic involvement of connective tissue	0.994	0.006	0.000
Chapter VII Diseases of the eye and adnexa	0.994	0.006	0.000
E10.1 With ketoacidosis	0.992	0.008	0.000
M35.0 Sicca syndrome [Sjogren]	0.992	0.008	0.000
H30-H36 Disorders of choroid and retina	0.990	0.010	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.990	0.010	0.000
E14.3 With ophthalmic complications	0.989	0.011	0.000
M35.3 Polymyalgia rheumatica	0.989	0.011	0.000
K70-K77 Diseases of liver	0.987	0.013	0.000
M20-M25 Other joint disorders	0.986	0.014	0.000
E16 Other disorders of pancreatic internal secretion	0.982	0.018	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.981	0.019	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.976	0.024	0.000
E16.2 Hypoglycaemia, unspecified	0.976	0.024	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.971	0.029	0.000
K75 Other inflammatory liver diseases	0.970	0.030	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.968	0.032	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.967	0.033	0.000
J45.9 Asthma, unspecified	0.967	0.033	0.000
E10.2 With renal complications	0.966	0.034	0.000
K75.4 Autoimmune hepatitis	0.966	0.034	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.965	0.035	0.000
J45 Asthma	0.962	0.038	0.000
J40-J47 Chronic lower respiratory diseases	0.960	0.040	0.000
M34 Systemic sclerosis	0.960	0.040	0.000
E83.1 Disorders of iron metabolism	0.000	0.040	0.960
Chapter X Diseases of the respiratory system	0.958	0.042	0.000
H36 Retinal disorders in diseases classified elsewhere	0.956	0.044	0.000
H35 Other retinal disorders	0.950	0.050	0.000
J43 Emphysema	0.950	0.050	0.000
H35.8 Other specified retinal disorders	0.949	0.051	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.944	0.056	0.000
H50 Other strabismus	0.938	0.062	0.000
K73 Chronic hepatitis, not elsewhere classified	0.937	0.063	0.000
E06 Thyroiditis	0.933	0.067	0.000
K60 Fissure and fistula of anal and rectal regions	0.933	0.067	0.000
H36.0 Diabetic retinopathy	0.932	0.068	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.923	0.077	0.000
K50-K52 Noninfective enteritis and colitis	0.921	0.079	0.000
J43.9 Emphysema, unspecified	0.920	0.080	0.000
E10.4 With neurological complications	0.920	0.080	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.919	0.081	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.918	0.082	0.000
K52 Other non-infective gastro-enteritis and colitis	0.915	0.085	0.000
E06.3 Autoimmune thyroiditis	0.903	0.097	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.902	0.098	0.000
K60.5 Anorectal fistula	0.902	0.098	0.000
H05 Disorders of orbit	0.900	0.100	0.000
D60-D64 Aplastic and other anaemias	0.898	0.102	0.000
M06.0 Seronegative rheumatoid arthritis	0.884	0.116	0.000
H06.2 Dysthyroid exophthalmos	0.883	0.117	0.000
E14.9 Without complications	0.881	0.119	0.000
L50-L54 Urticaria and erythema	0.877	0.123	0.000
E10.0 With coma	0.873	0.127	0.000
H04 Disorders of lachrymal system	0.871	0.129	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.871	0.129	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.870	0.130	0.000
M34.9 Systemic sclerosis, unspecified	0.864	0.136	0.000
K74 Fibrosis and cirrhosis of liver	0.864	0.136	0.000
M10 Gout	0.864	0.136	0.000
M06.3 Rheumatoid nodule	0.863	0.136	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.858	0.142	0.000
M35.1 Other overlap syndromes	0.852	0.148	0.000
H50.5 Heterophoria	0.851	0.149	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.849	0.151	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.842	0.158	0.000
M34.1 CR(E)ST syndrome	0.840	0.160	0.000
L20-L30 Dermatitis and eczema	0.836	0.164	0.000
H52 Disorders of refraction and accommodation	0.834	0.166	0.000
K75.8 Other specified inflammatory liver diseases	0.833	0.167	0.000
J43.2 Centrilobular emphysema	0.830	0.170	0.000
H52.1 Myopia	0.829	0.171	0.000
H50.0 Convergent concomitant strabismus	0.829	0.171	0.000
H34 Retinal vascular occlusions	0.827	0.173	0.000
M08 Juvenile arthritis	0.827	0.173	0.000
M32 Systemic lupus erythematosus	0.823	0.177	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.822	0.178	0.000
L52 Erythema nodosum	0.818	0.182	0.000
D80-D89 Certain disorders involving the immune mechanism	0.816	0.184	0.000
M34.8 Other forms of systemic sclerosis	0.816	0.184	0.000
H04.4 Chronic inflammation of lachrymal passages	0.816	0.184	0.000
K73.9 Chronic hepatitis, unspecified	0.815	0.185	0.000
E07 Other disorders of thyroid	0.814	0.186	0.000
E14.2 Withrenal complications	0.814	0.186	0.000
K60.4 Rectal fistula	0.813	0.187	0.000
H31 Other disorders of choroid	0.809	0.191	0.000
D69 Purpura and other haemorrhagic conditions	0.807	0.193	0.000
J43.8 Other emphysema	0.806	0.194	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.805	0.195	0.000
K74.3 Primary biliary cirrhosis	0.805	0.195	0.000
E13 Other specified diabetes mellitus	0.805	0.195	0.000
D64 Other anaemias	0.803	0.197	0.000
J86 Pyothorax	0.799	0.201	0.000
M12 Other specific arthropathies	0.795	0.205	0.000
H05.0 Acute inflammation of orbit	0.794	0.206	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.792	0.208	0.000
E14.1 With ketoacidosis	0.789	0.211	0.000
L10-L14 Bullous disorders	0.788	0.212	0.000
E40-E46 Malnutrition	0.787	0.213	0.000
K90.9 Intestinal malabsorption, unspecified	0.786	0.214	0.000
E10.7 With multiple complications	0.785	0.215	0.000
H50.9 Strabismus, unspecified	0.784	0.216	0.000
E14.6 With other specified complications	0.782	0.218	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.781	0.219	0.000
J84 Other interstitial pulmonary diseases	0.779	0.221	0.000
K77 Liver disorders in diseases classified elsewhere	0.779	0.221	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.779	0.221	0.000
D55-D59 Haemolytic anaemias	0.778	0.222	0.000
H01 Other inflammation of eyelid	0.776	0.224	0.000
E10.8 With unspecified complications	0.775	0.225	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.771	0.229	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.770	0.230	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.766	0.234	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.766	0.234	0.000
H30 Chorioretinal inflammation	0.764	0.236	0.000
H50.6 Mechanical strabismus	0.763	0.237	0.000
M06.34 Rheumatoid nodule (Hand)	0.760	0.240	0.000
M06.4 Inflammatory polyarthropathy	0.759	0.241	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.757	0.243	0.000
H04.1 Other disorders of lachrymal gland	0.754	0.246	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.754	0.246	0.000
K60.0 Acute anal fissure	0.751	0.249	0.000
H05.8 Other disorders of orbit	0.751	0.249	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.749	0.251	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.749	0.251	0.000
H05.2 Exophthalmic conditions	0.748	0.252	0.000
K71 Toxic liver disease	0.747	0.253	0.000
D62 Acute posthaemorrhagic anaemia	0.746	0.254	0.000
M06.8 Other specified rheumatoid arthritis	0.746	0.254	0.000
D64.9 Anaemia, unspecified	0.745	0.255	0.000
H34.2 Other retinal artery occlusions	0.744	0.256	0.000
K72 Hepatic failure, not elsewhere classified	0.743	0.257	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.741	0.259	0.000
H35.2 Other proliferative retinopathy	0.740	0.260	0.000
L40-L45 Papulosquamous disorders	0.720	0.262	0.018
E07.8 Other specified disorders of thyroid	0.738	0.262	0.000
L94 Other localised connective tissue disorders	0.737	0.263	0.000
L28 Lichen simplex chronicus and prurigo	0.737	0.263	0.000
M35.2 Behcet's disease	0.737	0.263	0.000
Chapter I Certain infectious and parasitic diseases	0.735	0.265	0.000
G35 Multiple sclerosis	0.000	0.268	0.732
D69.6 Thrombocytopenia, unspecified	0.731	0.269	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.731	0.269	0.000
K90.8 Other intestinal malabsorption	0.727	0.273	0.000
M35.7 Hypermobility syndrome	0.726	0.274	0.000
M34.0 Progressive systemic sclerosis	0.725	0.274	0.000
D69.4 Other primary thrombocytopenia	0.722	0.278	0.000
M10.9 Gout, unspecified	0.720	0.280	0.000
L51 Erythema multiforme	0.720	0.280	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.717	0.283	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.717	0.283	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.717	0.283	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.717	0.283	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.717	0.283	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
K90.3 Pancreatic steatorrhoea	0.715	0.285	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.715	0.285	0.000
K90.1 Tropical sprue	0.715	0.285	0.000
L29 Pruritus	0.715	0.285	0.000
E14.7 With multiple complications	0.715	0.285	0.000
E14.0 With coma	0.715	0.285	0.000
E05.8 Other thyrotoxicosis	0.715	0.285	0.000
H35.4 Peripheral retinal degeneration	0.714	0.286	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.714	0.286	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.713	0.287	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.713	0.287	0.000
M35.5 Multifocal fibrosclerosis	0.713	0.287	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.713	0.287	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.710	0.290	0.000
E15 Nondiabetic hypoglycaemic coma	0.710	0.290	0.000
J86.0 Pyothorax with fistula	0.708	0.292	0.000
E16.1 Other hypoglycaemia	0.706	0.294	0.000
M35.8 Other specified systemic involvement of connective tissue	0.705	0.295	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.704	0.296	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.704	0.296	0.000
E16.4 Abnormal secretion of gastrin	0.704	0.296	0.000
E16.3 Increased secretion of glucagon	0.704	0.296	0.000
L13 Other bullous disorders	0.702	0.298	0.000
H01.9 Inflammation of eyelid, unspecified	0.702	0.298	0.000
H35.6 Retinal haemorrhage	0.701	0.299	0.000
H35.7 Separation of retinal layers	0.701	0.299	0.000
M15-M19 Arthrosis	0.701	0.299	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.699	0.301	0.000
L50 Urticaria	0.699	0.301	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.697	0.303	0.000
H50.2 Vertical strabismus	0.697	0.303	0.000
M10.0 Idiopathic gout	0.697	0.303	0.000
K74.5 Biliary cirrhosis, unspecified	0.697	0.303	0.000
M18 Arthrosis of first carpometacarpal joint	0.696	0.304	0.000
L29.2 Pruritus vulvae	0.696	0.304	0.000
K75.2 Nonspecific reactive hepatitis	0.695	0.305	0.000
K75.1 Phlebitis of portal vein	0.695	0.305	0.000
H31.1 Choroidal degeneration	0.694	0.306	0.000
M14 Arthropathies in other diseases classified elsewhere	0.694	0.306	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.693	0.307	0.000
E14.8 With unspecified complications	0.693	0.307	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.691	0.309	0.000
E10.6 With other specified complications	0.690	0.310	0.000
M49 Spondylopathies in diseases classified elsewhere	0.689	0.311	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.688	0.312	0.000
H51 Other disorders of binocular movement	0.688	0.312	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.688	0.312	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.687	0.313	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.685	0.314	0.000
K55-K64 Other diseases of intestines	0.683	0.317	0.000
H35.1 Retinopathy of prematurity	0.681	0.319	0.000
J43.1 Panlobular emphysema	0.681	0.319	0.000
J43.0 MacLeod's syndrome	0.681	0.319	0.000
J45.1 Nonallergic asthma	0.679	0.321	0.000
J45.0 Predominantly allergic asthma	0.679	0.321	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.679	0.321	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.323	0.677
L43 Lichen planus	0.668	0.325	0.007
J41 Simple and mucopurulent chronic bronchitis	0.675	0.325	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.674	0.326	0.000
L25 Unspecified contact dermatitis	0.674	0.326	0.000
B35-B49 Mycoses	0.673	0.327	0.000
H50.3 Intermittent heterotropia	0.673	0.327	0.000
J86.9 Pyothorax without fistula	0.672	0.328	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.672	0.328	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.672	0.328	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.672	0.328	0.000
H04.8 Other disorders of lachrymal system	0.671	0.329	0.000
E06.5 Other chronic thyroiditis	0.670	0.330	0.000
M08.9 Juvenile arthritis, unspecified	0.670	0.330	0.000
M05 Seropositive rheumatoid arthritis	0.670	0.330	0.000
E06.4 Drug-induced thyroiditis	0.669	0.331	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.669	0.331	0.000
E06.1 Subacute thyroiditis	0.669	0.331	0.000
E06.0 Acute thyroiditis	0.669	0.331	0.000
L94.9 Localised connective tissue disorder, unspecified	0.668	0.332	0.000
E13.9 Without complications	0.667	0.332	0.000
H50.1 Divergent concomitant strabismus	0.667	0.333	0.000
D61 Other aplastic anaemias	0.667	0.333	0.000
D84 Other immunodeficiencies	0.666	0.334	0.000
E14.5 With peripheral circulatory complications	0.665	0.334	0.000
Chapter VIII Diseases of the ear and mastoid process	0.665	0.335	0.000
M10.94 Gout, unspecified (Hand)	0.664	0.336	0.000
B35 Dermatophytosis	0.663	0.337	0.000
L23 Allergic contact dermatitis	0.662	0.338	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.662	0.338	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.339	0.660
K72.0 Acute and subacute hepatic failure	0.660	0.340	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.658	0.341	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.658	0.341	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.658	0.341	0.000
J44 Other chronic obstructive pulmonary disease	0.656	0.344	0.000
M00-M03 Infectious arthropathies	0.656	0.344	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.653	0.347	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.347	0.653
J85 Abscess of lung and mediastinum	0.652	0.348	0.000
J33 Nasal polyp	0.648	0.352	0.000
L20 Atopic dermatitis	0.646	0.354	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.645	0.355	0.000
H05.3 Deformity of orbit	0.645	0.355	0.000
H05.1 Chronic inflammatory disorders of orbit	0.645	0.355	0.000
D83 Common variable immunodeficiency	0.644	0.355	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.644	0.356	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.644	0.356	0.000
M08.0 Juvenile rheumatoid arthritis	0.643	0.357	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.643	0.357	0.000
D69.8 Other specified haemorrhagic conditions	0.643	0.357	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.643	0.357	0.000
L94.0 Localised scleroderma [morphea]	0.642	0.358	0.000
H01.8 Other specified inflammation of eyelid	0.642	0.358	0.000
L13.0 Dermatitis herpetiformis	0.641	0.359	0.000
D69.2 Other nonthrombocytopenic purpura	0.639	0.361	0.000
J33.0 Polyp of nasal cavity	0.639	0.361	0.000
A30-A49 Other bacterial diseases	0.639	0.361	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.638	0.362	0.000
E14.4 With neurological complications	0.637	0.363	0.000
D80 Immunodeficiency with predominantly antibody defects	0.637	0.363	0.000
L80 Vitiligo	0.636	0.363	0.000
L90 Atrophic disorders of skin	0.636	0.364	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.636	0.364	0.000
J33.9 Nasal polyp, unspecified	0.635	0.365	0.000
D50-D53 Nutritional anaemias	0.635	0.365	0.000
K74.6 Other and unspecified cirrhosis of liver	0.634	0.366	0.000
L43.9 Lichen planus, unspecified	0.633	0.366	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.633	0.366	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.633	0.366	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.633	0.366	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.633	0.366	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.633	0.366	0.000
E46 Unspecified protein-energy malnutrition	0.634	0.366	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.633	0.367	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.632	0.368	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.630	0.370	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.630	0.370	0.000
J30-J39 Other diseases of upper respiratory tract	0.629	0.371	0.000
L54 Erythema in diseases classified elsewhere	0.628	0.371	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.627	0.373	0.000
H04.0 Dacryoadenitis	0.625	0.375	0.000
E20-E35 Disorders of other endocrine glands	0.623	0.377	0.000
M12.5 Traumatic arthropathy	0.621	0.379	0.000
K74.4 Secondary biliary cirrhosis	0.619	0.380	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.619	0.380	0.000
K74.1 Hepatic sclerosis	0.619	0.380	0.000
M10.4 Other secondary gout	0.619	0.381	0.000
M10.3 Gout due to impairment of renal function	0.619	0.381	0.000
M10.2 Drug-induced gout	0.619	0.381	0.000
M10.1 Lead-induced gout	0.619	0.381	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.619	0.381	0.000
M06.38 Rheumatoid nodule (Other)	0.619	0.381	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.619	0.381	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.619	0.381	0.000
M06.33 Rheumatoid nodule (Forearm)	0.619	0.381	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.619	0.381	0.000
M10.90 Gout, unspecified (Multiple sites)	0.619	0.381	0.000
L51.9 Erythema multiforme, unspecified	0.617	0.383	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.617	0.383	0.000
H60-H62 Diseases of external ear	0.616	0.384	0.000
K80 Cholelithiasis	0.615	0.385	0.000
K71.0 Toxic liver disease with cholestasis	0.614	0.386	0.000
L28.0 Lichen simplex chronicus	0.613	0.387	0.000
H50.8 Other specified strabismus	0.612	0.388	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.612	0.388	0.000
D69.0 Allergic purpura	0.612	0.388	0.000
L94.8 Other specified localised connective tissue disorders	0.611	0.389	0.000
J46 Status asthmaticus	0.611	0.389	0.000
D69.5 Secondary thrombocytopenia	0.610	0.390	0.000
B35.1 Tinea unguium	0.610	0.390	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.610	0.390	0.000
K83 Other diseases of biliary tract	0.609	0.391	0.000
B35.6 Tinea cruris	0.609	0.391	0.000
J45.8 Mixed asthma	0.608	0.392	0.000
H30.2 Posterior cyclitis	0.608	0.392	0.000
H05.4 Enophthalmos	0.608	0.392	0.000
L94.2 Calcinosis cutis	0.607	0.393	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.606	0.394	0.000
H05.9 Disorder of orbit, unspecified	0.605	0.395	0.000
M32.8 Other forms of systemic lupus erythematosus	0.605	0.395	0.000
H34.9 Retinal vascular occlusion, unspecified	0.604	0.396	0.000
D67 Hereditary factor IX deficiency	0.604	0.396	0.000
D58 Other hereditary haemolytic anaemias	0.603	0.397	0.000
H49 Paralytic strabismus	0.603	0.397	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.602	0.398	0.000
M60-M63 Disorders of muscles	0.602	0.398	0.000
K83.0 Cholangitis	0.602	0.398	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.601	0.399	0.000
E10.5 With peripheral circulatory complications	0.601	0.399	0.000
L90.0 Lichen sclerosus et atrophicus	0.601	0.399	0.000
D56 Thalassaemia	0.600	0.399	0.000
H10-H13 Disorders of conjunctiva	0.600	0.400	0.000
L24 Irritant contact dermatitis	0.600	0.400	0.000
L26 Exfoliative dermatitis	0.600	0.400	0.000
L22 Diaper [napkin] dermatitis	0.600	0.400	0.000
E03.1 Congenital hypothyroidism without goitre	0.599	0.401	0.000
H52.6 Other disorders of refraction	0.598	0.402	0.000
H52.5 Disorders of accommodation	0.598	0.402	0.000
H18 Other disorders of cornea	0.594	0.406	0.000
H52.4 Presbyopia	0.594	0.406	0.000
H50.4 Other and unspecified heterotropia	0.594	0.406	0.000
H34.0 Transient retinal artery occlusion	0.593	0.407	0.000
M08.8 Other juvenile arthritis	0.593	0.407	0.000
M08.4 Pauciarticular juvenile arthritis	0.593	0.407	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.593	0.407	0.000
M08.2 Juvenile arthritis with systemic onset	0.593	0.407	0.000
M08.1 Juvenile ankylosing spondylitis	0.593	0.407	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.592	0.408	0.000
K81 Cholecystitis	0.592	0.408	0.000
E03.8 Other specified hypothyroidism	0.592	0.408	0.000
H15 Disorders of sclera	0.591	0.409	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.590	0.410	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.590	0.410	0.000
K81.9 Cholecystitis, unspecified	0.590	0.410	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.590	0.410	0.000
H61 Other disorders of external ear	0.590	0.410	0.000
L53 Other erythematous conditions	0.590	0.410	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.590	0.410	0.000
M11 Other crystal arthropathies	0.589	0.411	0.000
H21 Other disorders of iris and ciliary body	0.589	0.411	0.000
L28.1 Prurigo nodularis	0.588	0.412	0.000
H16 Keratitis	0.587	0.413	0.000
A63.0 Anogenital (venereal) warts	0.587	0.413	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.586	0.414	0.000
D81 Combined immunodeficiencies	0.585	0.415	0.000
E22 Hyperfunction of pituitary gland	0.584	0.416	0.000
A41 Other septicaemia	0.584	0.416	0.000
E07.1 Dyshormogenetic goitre	0.584	0.416	0.000
E07.0 Hypersecretion of calcitonin	0.584	0.416	0.000
J84.0 Alveolar and parietoalveolar conditions	0.583	0.417	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.582	0.418	0.000
B25-B34 Other viral diseases	0.580	0.420	0.000
H31.4 Choroidal detachment	0.580	0.420	0.000
H31.2 Hereditary choroidal dystrophy	0.580	0.420	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.579	0.421	0.000
D69.1 Qualitative platelet defects	0.579	0.421	0.000
L50.1 Idiopathic urticaria	0.579	0.421	0.000
H31.8 Other specified disorders of choroid	0.579	0.421	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.578	0.422	0.000
E27 Other disorders of adrenal gland	0.578	0.422	0.000
E13.8 With unspecified complications	0.577	0.423	0.000
E13.7 With multiple complications	0.577	0.423	0.000
E13.6 With other specified complications	0.577	0.423	0.000
E13.5 With peripheral circulatory complications	0.577	0.423	0.000
E13.4 With neurological complications	0.577	0.423	0.000
E13.2 With renal complications	0.577	0.423	0.000
E13.1 With ketoacidosis	0.577	0.423	0.000
E13.0 With coma	0.577	0.423	0.000
D64.4 Congenital dyserythropoietic anaemia	0.575	0.424	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.575	0.424	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.575	0.424	0.000
D64.0 Hereditary sideroblastic anaemia	0.575	0.424	0.000
L10 Pemphigus	0.575	0.424	0.000
H31.3 Choroidal haemorrhage and rupture	0.575	0.425	0.000
E27.1 Primary adrenocortical insufficiency	0.575	0.425	0.000
E13.3 With ophthalmic complications	0.574	0.426	0.000
D64.3 Other sideroblastic anaemias	0.574	0.426	0.000
L84 Corns and callosities	0.573	0.427	0.000
D86 Sarcoidosis	0.573	0.427	0.000
H31.0 Chorioretinal scars	0.572	0.428	0.000
L28.2 Other prurigo	0.572	0.428	0.000
M12.2 Villonodular synovitis (pigmented)	0.572	0.428	0.000
M12.4 Intermittent hydrarthrosis	0.570	0.430	0.000
M12.1 Kaschin-Beck disease	0.570	0.430	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.570	0.430	0.000
D59 Acquired haemolytic anaemia	0.569	0.431	0.000
H35.5 Hereditary retinal dystrophy	0.566	0.434	0.000
H61.8 Other specified disorders of external ear	0.565	0.435	0.000
L14 Bullous disorders in diseases classified elsewhere	0.565	0.435	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.564	0.436	0.000
E45 Retarded development following protein-energy malnutrition	0.564	0.436	0.000
E43 Unspecified severe protein-energy malnutrition	0.564	0.436	0.000
E42 Marasmic kwashiorkor	0.564	0.436	0.000
E41 Nutritional marasmus	0.564	0.436	0.000
E40 Kwashiorkor	0.564	0.436	0.000
H31.9 Disorder of choroid, unspecified	0.564	0.436	0.000
M30 Polyarteritis nodosa and related conditions	0.563	0.436	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.563	0.437	0.000
M12.3 Palindromic rheumatism	0.562	0.438	0.000
D84.8 Other specified immunodeficiencies	0.560	0.440	0.000
L93 Lupus erythematosus	0.560	0.440	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.558	0.441	0.000
A41.9 Septicaemia, unspecified	0.558	0.442	0.000
L25.9 Unspecified contact dermatitis, unspecified cause	0.558	0.442	0.000
D57 Sickle-cell disorders	0.558	0.442	0.000
D55 Anaemia due to enzyme disorders	0.558	0.442	0.000
M08.99 Juvenile arthritis, unspecified (Site unspecified)	0.557	0.443	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.557	0.443	0.000
B35.3 Tinea pedis	0.557	0.443	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.556	0.444	0.000
M31 Other necrotising vasculopathies	0.556	0.444	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.555	0.445	0.000
B15-B19 Viral hepatitis	0.554	0.446	0.000
J95-J99 Other diseases of the respiratory system	0.554	0.446	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.552	0.448	0.000
L12 Pemphigoid	0.550	0.450	0.000
J47 Bronchiectasis	0.549	0.451	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.548	0.452	0.000
H34.1 Central retinal artery occlusion	0.548	0.452	0.000
H30.8 Other chorioretinal inflammations	0.548	0.452	0.000
H30.1 Disseminated chorioretinal inflammation	0.548	0.452	0.000
H30.0 Focal chorioretinal inflammation	0.548	0.452	0.000
H20 Iridocyclitis	0.547	0.452	0.000
J33.1 Polypoid sinus degeneration	0.547	0.453	0.000
H04.6 Other changes in lachrymal passages	0.547	0.453	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.547	0.453	0.000
L11 Other acantholytic disorders	0.545	0.455	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations