TreeWAS – Variant ID: rs2240919

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M16.1 Other primary coxarthrosis	0.939	0.061	0.000
M16 Coxarthrosis [arthrosis of hip]	0.915	0.085	0.000
M16.9 Coxarthrosis, unspecified	0.896	0.104	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.768	0.232	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.674	0.326	0.000
M16.3 Other dysplastic coxarthrosis	0.672	0.328	0.000
M16.0 Primary coxarthrosis, bilateral	0.669	0.331	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.656	0.344	0.000
M15-M19 Arthrosis	0.635	0.365	0.000
M18 Arthrosis of first carpometacarpal joint	0.632	0.368	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.606	0.394	0.000
M16.5 Other posttraumatic coxarthrosis	0.606	0.394	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.592	0.408	0.000
M16.7 Other secondary coxarthrosis	0.553	0.447	0.000
H25.8 Other senile cataract	0.000	0.449	0.551
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.490	0.510	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.487	0.512	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.453	0.547	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.453	0.547	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.453	0.547	0.000
M15 Polyarthrosis	0.328	0.671	0.000
M15.8 Other polyarthrosis	0.265	0.735	0.000
M15.3 Secondary multiple arthrosis	0.246	0.753	0.000
M15.0 Primary generalised (osteo)arthrosis	0.235	0.764	0.000
M15.4 Erosive (osteo)arthrosis	0.235	0.764	0.000
M15.9 Polyarthrosis, unspecified	0.218	0.781	0.000
K60.1 Chronic anal fissure	0.000	0.811	0.189
M15.1 Heberden's nodes (with arthropathy)	0.180	0.819	0.001
M17 Gonarthrosis [arthrosis of knee]	0.177	0.823	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.169	0.831	0.000
H25 Senile cataract	0.000	0.844	0.156
K60 Fissure and fistula of anal and rectal regions	0.000	0.848	0.152
M17.2 Posttraumatic gonarthrosis, bilateral	0.144	0.856	0.000
M17.0 Primary gonarthrosis, bilateral	0.141	0.859	0.000
M15.99 Polyosteoarthritis, unspecified	0.139	0.860	0.001
M15.2 Bouchard's nodes (with arthropathy)	0.134	0.865	0.001
K60.4 Rectal fistula	0.000	0.865	0.135
M17.5 Other secondary gonarthrosis	0.130	0.870	0.000
K60.2 Anal fissure, unspecified	0.000	0.873	0.127
M19 Other arthrosis	0.123	0.877	0.000
K60.3 Anal fistula	0.000	0.877	0.123
K60.5 Anorectal fistula	0.000	0.881	0.119
H25.1 Senile nuclear cataract	0.000	0.883	0.117
M17.4 Other secondary gonarthrosis, bilateral	0.117	0.883	0.000
H25.2 Senile cataract, morgagnian type	0.000	0.888	0.112
M17.3 Other posttraumatic gonarthrosis	0.107	0.893	0.000
H25.9 Senile cataract, unspecified	0.000	0.895	0.105
M19.8 Other specified arthrosis	0.098	0.902	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.098	0.902	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.095	0.905	0.000
K60.0 Acute anal fissure	0.000	0.906	0.094
M05-M14 Inflammatory polyarthropathies	0.094	0.906	0.000
M80-M85 Disorders of bone density and structure	0.093	0.907	0.000
M85 Other disorders of bone density and structure	0.087	0.913	0.000
M06 Other rheumatoid arthritis	0.086	0.914	0.000
M87 Osteonecrosis	0.085	0.915	0.000
M86-M90 Other osteopathies	0.085	0.915	0.000
M87.9 Osteonecrosis, unspecified	0.083	0.917	0.000
M11 Other crystal arthropathies	0.082	0.918	0.000
M80 Osteoporosis with pathological fracture	0.081	0.919	0.000
M19.1 Posttraumatic arthrosis of other joints	0.080	0.920	0.000
M06.3 Rheumatoid nodule	0.079	0.921	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.078	0.922	0.000
M19.2 Other secondary arthrosis	0.077	0.923	0.000
M05 Seropositive rheumatoid arthritis	0.077	0.923	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.076	0.924	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.076	0.924	0.000
M81 Osteoporosis without pathological fracture	0.076	0.924	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.076	0.924	0.000
M85.6 Other cyst of bone	0.076	0.924	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.074	0.925	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.074	0.926	0.000
M85.2 Hyperostosis of skull	0.073	0.927	0.000
M06.34 Rheumatoid nodule (Hand)	0.072	0.928	0.000
M14 Arthropathies in other diseases classified elsewhere	0.072	0.928	0.000
M11.2 Other chondrocalcinosis	0.072	0.928	0.000
M12 Other specific arthropathies	0.071	0.929	0.000
M13 Other arthritis	0.071	0.929	0.000
M81.4 Drug-induced osteoporosis	0.071	0.929	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.071	0.929	0.000
M19.88 Other specified arthrosis (Other)	0.071	0.929	0.000
M19.86 Other specified arthrosis (Lower leg)	0.071	0.929	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.071	0.929	0.000
M19.84 Other specified arthrosis (Hand)	0.071	0.929	0.000
M19.83 Other specified arthrosis (Forearm)	0.071	0.929	0.000
M19.82 Other specified arthrosis (Upper arm)	0.071	0.929	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.071	0.929	0.000
M06.0 Seronegative rheumatoid arthritis	0.071	0.929	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.070	0.930	0.000
M83 Adult osteomalacia	0.070	0.930	0.000
M87.2 Osteonecrosis due to previous trauma	0.069	0.931	0.000
M85.0 Fibrous dysplasia (monostotic)	0.068	0.932	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.068	0.932	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.067	0.932	0.000
M08 Juvenile arthritis	0.067	0.932	0.000
M00-M03 Infectious arthropathies	0.067	0.933	0.000
M87.8 Other osteonecrosis	0.067	0.933	0.000
M87.1 Osteonecrosis due to drugs	0.067	0.933	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.066	0.933	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.066	0.934	0.000
M91-M94 Chondropathies	0.066	0.934	0.000
M11.9 Crystal arthropathy, unspecified	0.065	0.935	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.064	0.936	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.064	0.936	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.064	0.936	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.063	0.937	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.063	0.937	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.063	0.937	0.000
M85.20 Hyperostosis of skull-Mult sites	0.063	0.937	0.000
M85.9 Disorder of bone density and structure, unspecified	0.062	0.938	0.000
M85.5 Aneurysmal bone cyst	0.062	0.938	0.000
M85.4 Solitary bone cyst	0.062	0.938	0.000
M85.3 Osteitis condensans	0.062	0.938	0.000
M85.1 Skeletal fluorosis	0.062	0.938	0.000
M13.8 Other specified arthritis	0.062	0.938	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.062	0.938	0.000
M06.8 Other specified rheumatoid arthritis	0.062	0.938	0.000
M06.2 Rheumatoid bursitis	0.062	0.938	0.000
M06.1 Adult-onset Still's disease	0.062	0.938	0.000
M85.8 Other specified disorders of bone density and structure	0.062	0.938	0.000
M06.4 Inflammatory polyarthropathy	0.062	0.938	0.000
M87.3 Other secondary osteonecrosis	0.061	0.939	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.061	0.939	0.000
M60-M63 Disorders of muscles	0.061	0.939	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.061	0.939	0.000
M85.68 Other cyst of bone (Other)	0.061	0.939	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.060	0.940	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.060	0.940	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.060	0.940	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.060	0.940	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.060	0.940	0.000
M10 Gout	0.060	0.940	0.000
M13.0 Polyarthritis, unspecified	0.060	0.940	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.059	0.940	0.000
M11.1 Familial chondrocalcinosis	0.059	0.941	0.000
M11.0 Hydroxyapatite deposition disease	0.059	0.941	0.000
M06.9 Rheumatoid arthritis, unspecified	0.059	0.941	0.000
M82 Osteoporosis in diseases classified elsewhere	0.059	0.941	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.059	0.941	0.000
M05.2 Rheumatoid vasculitis	0.059	0.941	0.000
M11.8 Other specified crystal arthropathies	0.059	0.941	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.058	0.941	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.058	0.941	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.058	0.941	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.058	0.942	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.058	0.942	0.000
M85.66 Other cyst of bone (Lower leg)	0.058	0.942	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.057	0.942	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.057	0.942	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.057	0.942	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.057	0.942	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.057	0.942	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.057	0.942	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.057	0.943	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.057	0.943	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.057	0.943	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.057	0.943	0.000
M99 Biomechanical lesions, not elsewhere classified	0.057	0.943	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.057	0.943	0.000
M06.38 Rheumatoid nodule (Other)	0.057	0.943	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.057	0.943	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.057	0.943	0.000
M06.33 Rheumatoid nodule (Forearm)	0.057	0.943	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.057	0.943	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.056	0.944	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.056	0.944	0.000
M12.5 Traumatic arthropathy	0.056	0.944	0.000
M81.8 Other osteoporosis	0.056	0.944	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.055	0.944	0.000
M19.28 Other secondary arthrosis (Other)	0.055	0.944	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.055	0.944	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.055	0.944	0.000
M19.24 Other secondary arthrosis (Hand)	0.055	0.944	0.000
M19.23 Other secondary arthrosis (Forearm)	0.055	0.944	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.055	0.944	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.055	0.944	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.055	0.944	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.055	0.945	0.000
M81.0 Postmenopausal osteoporosis	0.055	0.945	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.055	0.945	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.055	0.945	0.000
M05.1 Rheumatoid lung disease	0.055	0.945	0.000
M05.0 Felty's syndrome	0.055	0.945	0.000
M13.89 Other specified arthritis (Site unspecified)	0.055	0.945	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.055	0.945	0.000
M81.6 Localised osteoporosis [Lequesne]	0.055	0.945	0.000
M81.5 Idiopathic osteoporosis	0.055	0.945	0.000
M81.1 Postoophorectomy osteoporosis	0.055	0.945	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.055	0.945	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.055	0.945	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.055	0.945	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.055	0.945	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.055	0.945	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.055	0.945	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.055	0.945	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.055	0.945	0.000
M05.8 Other seropositive rheumatoid arthritis	0.055	0.945	0.000
M88 Paget's disease of bone [osteitis deformans]	0.054	0.945	0.000
M85.69 Other cyst of bone (Site unspecified)	0.054	0.945	0.000
M85.63 Other cyst of bone (Forearm)	0.054	0.945	0.000
M85.62 Other cyst of bone (Upper arm)	0.054	0.945	0.000
M85.61 Other cyst of bone (Shoulder region)	0.054	0.945	0.000
M85.60 Other cyst of bone (Multiple sites)	0.054	0.945	0.000
H25.0 Senile incipient cataract	0.000	0.946	0.054
M83.1 Senile osteomalacia	0.054	0.946	0.000
M81.2 Osteoporosis of disuse	0.054	0.946	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.054	0.946	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.053	0.946	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.053	0.947	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.053	0.947	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.053	0.947	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.053	0.947	0.000
M40-M43 Deforming dorsopathies	0.053	0.947	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.053	0.947	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.053	0.947	0.000
M89 Other disorders of bone	0.053	0.947	0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.053	0.947	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.052	0.947	0.000
M85.29 Hyperostosis of skull-Site unspec	0.052	0.948	0.000
M85.28 Hyperostosis of skull-Other	0.052	0.948	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.052	0.948	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.052	0.948	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.052	0.948	0.000
M85.24 Hyperostosis of skull-Hand	0.052	0.948	0.000
M85.23 Hyperostosis of skull-Forearm	0.052	0.948	0.000
M85.22 Hyperostosis of skull-Upper arm	0.052	0.948	0.000
M85.21 Hyperostosis of skull-Shldr region	0.052	0.948	0.000
M95.1 Cauliflower ear	0.052	0.948	0.000
M92 Other juvenile osteochondrosis	0.052	0.948	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.052	0.948	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.052	0.948	0.000
M14.4 Arthropathy in amyloidosis	0.052	0.948	0.000
M14.3 Lipoid dermatoarthritis	0.052	0.948	0.000
M14.2 Diabetic arthropathy	0.052	0.948	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.052	0.948	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.052	0.948	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.051	0.948	0.000
M11.28 Other chondrocalcinosis (Other)	0.051	0.948	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.051	0.948	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.051	0.948	0.000
M11.24 Other chondrocalcinosis (Hand)	0.051	0.948	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.051	0.948	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.051	0.948	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.051	0.948	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.051	0.948	0.000
M80.8 Other osteoporosis with pathological fracture	0.051	0.948	0.000
M85.64 Other cyst of bone (Hand)	0.051	0.948	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.051	0.948	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.051	0.949	0.000
M12.4 Intermittent hydrarthrosis	0.051	0.949	0.000
M12.1 Kaschin-Beck disease	0.051	0.949	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.051	0.949	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.051	0.949	0.000
M81.48 Drug-induced osteoporosis (Other)	0.051	0.949	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.051	0.949	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.051	0.949	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.051	0.949	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.051	0.949	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.051	0.949	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.051	0.949	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.051	0.949	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.051	0.949	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.051	0.949	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.051	0.949	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.051	0.949	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.051	0.949	0.000
M10.0 Idiopathic gout	0.051	0.949	0.000
M83.9 Adult osteomalacia, unspecified	0.051	0.949	0.000
M83.8 Other adult osteomalacia	0.051	0.949	0.000
M83.5 Other drug-induced osteomalacia in adults	0.051	0.949	0.000
M83.4 Aluminum bone disease	0.051	0.949	0.000
M83.3 Adult osteomalacia due to malnutrition	0.051	0.949	0.000
M83.2 Adult osteomalacia due to malabsorption	0.051	0.949	0.000
M83.0 Puerperal osteomalacia	0.051	0.949	0.000
M95.4 Acquired deformity of chest and rib	0.051	0.949	0.000
M12.2 Villonodular synovitis (pigmented)	0.050	0.949	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.050	0.950	0.000
M00 Pyogenic arthritis	0.050	0.950	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.049	0.950	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.049	0.950	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.049	0.950	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.049	0.950	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.049	0.950	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.049	0.950	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.049	0.950	0.000
M13.86 Other specified arthritis (Lower leg)	0.049	0.951	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.049	0.951	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.049	0.951	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.049	0.951	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.049	0.951	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.049	0.951	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.049	0.951	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.049	0.951	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.049	0.951	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.049	0.951	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.049	0.951	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.049	0.951	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.049	0.951	0.000
M08.9 Juvenile arthritis, unspecified	0.048	0.951	0.000
M08.8 Other juvenile arthritis	0.048	0.951	0.000
M08.4 Pauciarticular juvenile arthritis	0.048	0.951	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.048	0.951	0.000
M08.2 Juvenile arthritis with systemic onset	0.048	0.951	0.000
M08.1 Juvenile ankylosing spondylitis	0.048	0.951	0.000
M08.0 Juvenile rheumatoid arthritis	0.048	0.951	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.048	0.951	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.048	0.951	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.048	0.951	0.000
M09.0 Juvenile arthritis in psoriasis	0.048	0.951	0.000
M12.3 Palindromic rheumatism	0.048	0.951	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.048	0.952	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.048	0.952	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.048	0.952	0.000
M87.88 Other osteonecrosis (Other)	0.048	0.952	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.048	0.952	0.000
M87.86 Other osteonecrosis (Lower leg)	0.048	0.952	0.000
M87.84 Other osteonecrosis (Hand)	0.048	0.952	0.000
M87.83 Other osteonecrosis (Forearm)	0.048	0.952	0.000
M87.82 Other osteonecrosis (Upper arm)	0.048	0.952	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.048	0.952	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.048	0.952	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.048	0.952	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.048	0.952	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.048	0.952	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.048	0.952	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.048	0.952	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.048	0.952	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.048	0.952	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.048	0.952	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.048	0.952	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.048	0.952	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.048	0.952	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.048	0.952	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.047	0.952	0.000
M93 Other osteochondropathies	0.048	0.952	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.048	0.952	0.000
M14.6 Neuropathic arthropathy	0.048	0.952	0.000
F31 Bipolar affective disorder	0.000	0.952	0.048
M45-M49 Spondylopathies	0.047	0.953	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.047	0.953	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.047	0.953	0.000
M11.99 Crystal arthropathy, unspecified (Site unspecified)	0.047	0.953	0.000
M11.98 Crystal arthropathy, unspecified (Other)	0.047	0.953	0.000
M11.97 Crystal arthropathy, unspecified (Ankle and foot)	0.047	0.953	0.000
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)	0.047	0.953	0.000
M11.94 Crystal arthropathy, unspecified (Hand)	0.047	0.953	0.000
M11.93 Crystal arthropathy, unspecified (Forearm)	0.047	0.953	0.000
M11.92 Crystal arthropathy, unspecified (Upper arm)	0.047	0.953	0.000
M11.91 Crystal arthropathy, unspecified (Shoulder region)	0.047	0.953	0.000
M11.90 Crystal arthropathy, unspecified (Multiple sites)	0.047	0.953	0.000
M95.2 Other acquired deformity of head	0.047	0.953	0.000
M89.5 Osteolysis	0.047	0.953	0.000
M84 Disorders of continuity of bone	0.046	0.953	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.046	0.954	0.000
M13.1 Monoarthritis, not elsewhere classified	0.046	0.954	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.046	0.954	0.000
M92.6 Juvenile osteochondrosis of tarsus	0.046	0.954	0.000
M90 Osteopathies in diseases classified elsewhere	0.046	0.954	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.045	0.954	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.045	0.955	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.045	0.955	0.000
M95.5 Acquired deformity of pelvis	0.045	0.955	0.000
M95.3 Acquired deformity of neck	0.045	0.955	0.000
M12.57 Traumatic arthropathy (Ankle and foot)	0.045	0.955	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.045	0.955	0.000
M85.18 Skeletal fluorosis (Other)	0.045	0.955	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.045	0.955	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.045	0.955	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.045	0.955	0.000
M85.14 Skeletal fluorosis (Hand)	0.045	0.955	0.000
M85.13 Skeletal fluorosis (Forearm)	0.045	0.955	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.045	0.955	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.045	0.955	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.045	0.955	0.000
M85.39 Osteitis condensans (Site unspecified)	0.045	0.955	0.000
M85.38 Osteitis condensans (Other)	0.045	0.955	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.045	0.955	0.000
M85.36 Osteitis condensans (Lower leg)	0.045	0.955	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.045	0.955	0.000
M85.34 Osteitis condensans (Hand)	0.045	0.955	0.000
M85.33 Osteitis condensans (Forearm)	0.045	0.955	0.000
M85.32 Osteitis condensans (Upper arm)	0.045	0.955	0.000
M85.31 Osteitis condensans (Shoulder region)	0.045	0.955	0.000
M85.30 Osteitis condensans (Multiple sites)	0.045	0.955	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.045	0.955	0.000
M85.48 Solitary bone cyst (Other)	0.045	0.955	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.045	0.955	0.000
M85.46 Solitary bone cyst (Lower leg)	0.045	0.955	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.045	0.955	0.000
M85.44 Solitary bone cyst (Hand)	0.045	0.955	0.000
M85.43 Solitary bone cyst (Forearm)	0.045	0.955	0.000
M85.42 Solitary bone cyst (Upper arm)	0.045	0.955	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.045	0.955	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.045	0.955	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.045	0.955	0.000
M85.58 Aneurysmal bone cyst (Other)	0.045	0.955	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.045	0.955	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.045	0.955	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.045	0.955	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.045	0.955	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.045	0.955	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.045	0.955	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.045	0.955	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.045	0.955	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.045	0.955	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.045	0.955	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.045	0.955	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.045	0.955	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.045	0.955	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.045	0.955	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.045	0.955	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.045	0.955	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.045	0.955	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.045	0.955	0.000
M13.88 Other specified arthritis (Other)	0.045	0.955	0.000
M13.87 Other specified arthritis (Ankle and foot)	0.045	0.955	0.000
M13.85 Other specified arthritis (Pelvic region and thigh)	0.045	0.955	0.000
M13.84 Other specified arthritis (Hand)	0.045	0.955	0.000
M13.83 Other specified arthritis (Forearm)	0.045	0.955	0.000
M13.82 Other specified arthritis (Upper arm)	0.045	0.955	0.000
M13.81 Other specified arthritis (Shoulder region)	0.045	0.955	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.045	0.955	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.045	0.955	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.045	0.955	0.000
M06.18 Adult-onset Still's disease (Other)	0.045	0.955	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.045	0.955	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.045	0.955	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.045	0.955	0.000
M06.14 Adult-onset Still's disease (Hand)	0.045	0.955	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.045	0.955	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.045	0.955	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.045	0.955	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.045	0.955	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.045	0.955	0.000
M06.28 Rheumatoid bursitis (Other)	0.045	0.955	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.045	0.955	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.045	0.955	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.045	0.955	0.000
M06.24 Rheumatoid bursitis (Hand)	0.045	0.955	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.045	0.955	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.045	0.955	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.045	0.955	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.045	0.955	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.045	0.955	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.045	0.955	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.045	0.955	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.045	0.955	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.045	0.955	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.045	0.955	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.045	0.955	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.045	0.955	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.045	0.955	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.045	0.955	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.045	0.955	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.045	0.955	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.045	0.955	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.045	0.955	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.044	0.955	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.044	0.955	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.044	0.955	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.044	0.955	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.044	0.955	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.044	0.955	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.044	0.955	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.044	0.955	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.044	0.956	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.044	0.956	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.044	0.956	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.044	0.956	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.044	0.956	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.044	0.956	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.044	0.956	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.044	0.956	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.044	0.956	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.044	0.956	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.044	0.956	0.000
M87.38 Other secondary osteonecrosis (Other)	0.044	0.956	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.044	0.956	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.044	0.956	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.044	0.956	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.044	0.956	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.044	0.956	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.044	0.956	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.044	0.956	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.044	0.956	0.000
M07 Psoriatic and enteropathic arthropathies	0.044	0.956	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.044	0.956	0.000
M61 Calcification and ossification of muscle	0.044	0.956	0.000
M17.9 Gonarthrosis, unspecified	0.044	0.956	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.044	0.956	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.044	0.956	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.044	0.956	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.044	0.956	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.044	0.956	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.044	0.956	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.044	0.956	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.044	0.956	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.044	0.956	0.000
M91.2 Coxa plana	0.043	0.956	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.956	0.044

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations