TreeWAS – Variant ID: rs2248551

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11 Non-insulin-dependent diabetes mellitus	0.926	0.074	0.000
E11.9 Without complications	0.924	0.076	0.000
E11.3 With ophthalmic complications	0.920	0.080	0.000
E11.4 With neurological complications	0.903	0.097	0.000
E11.0 With coma	0.823	0.177	0.000
E11.6 With other specified complications	0.717	0.283	0.000
E11.8 With unspecified complications	0.715	0.285	0.000
E11.1 With ketoacidosis	0.711	0.289	0.000
E11.5 With peripheral circulatory complications	0.670	0.330	0.000
E11.7 With multiple complications	0.664	0.336	0.000
E10-E14 Diabetes mellitus	0.285	0.715	0.000
E11.2 With renal complications	0.261	0.738	0.001
E14 Unspecified diabetes mellitus	0.215	0.785	0.000
E12 Malnutrition-related diabetes mellitus	0.205	0.795	0.000
E13 Other specified diabetes mellitus	0.187	0.813	0.000
E14.2 Withrenal complications	0.168	0.832	0.000
E14.8 With unspecified complications	0.167	0.833	0.000
E14.4 With neurological complications	0.158	0.842	0.000
E14.7 With multiple complications	0.154	0.846	0.000
E14.5 With peripheral circulatory complications	0.154	0.846	0.000
E14.1 With ketoacidosis	0.154	0.846	0.000
E14.0 With coma	0.154	0.846	0.000
E14.6 With other specified complications	0.149	0.851	0.000
E10 Insulin-dependent diabetes mellitus	0.149	0.851	0.000
E12.9 Without complications	0.147	0.853	0.000
E12.8 With unspecified complications	0.147	0.853	0.000
E12.7 With multiple complications	0.147	0.853	0.000
E12.6 With other specified complications	0.147	0.853	0.000
E12.5 With peripheral circulatory complications	0.147	0.853	0.000
E12.4 With neurological complications	0.147	0.853	0.000
E12.3 With ophthalmic complications	0.147	0.853	0.000
E12.2 With renal complications	0.147	0.853	0.000
E12.1 With ketoacidosis	0.147	0.853	0.000
E12.0 With coma	0.147	0.853	0.000
E14.3 With ophthalmic complications	0.146	0.854	0.000
E14.9 Without complications	0.142	0.858	0.000
E13.8 With unspecified complications	0.134	0.866	0.000
E13.7 With multiple complications	0.134	0.866	0.000
E13.6 With other specified complications	0.134	0.866	0.000
E13.5 With peripheral circulatory complications	0.134	0.866	0.000
E13.4 With neurological complications	0.134	0.866	0.000
E13.3 With ophthalmic complications	0.134	0.866	0.000
E13.2 With renal complications	0.134	0.866	0.000
E13.1 With ketoacidosis	0.134	0.866	0.000
E13.0 With coma	0.134	0.866	0.000
E10.6 With other specified complications	0.122	0.878	0.000
E10.4 With neurological complications	0.120	0.880	0.000
E13.9 Without complications	0.116	0.884	0.000
E10.3 With ophthalmic complications	0.114	0.886	0.000
E10.5 With peripheral circulatory complications	0.112	0.888	0.000
E10.7 With multiple complications	0.107	0.893	0.000
E10.8 With unspecified complications	0.106	0.894	0.000
E10.0 With coma	0.101	0.898	0.000
O36 Maternal care for other known or suspected foetal problems	0.097	0.903	0.000
E10.2 With renal complications	0.093	0.907	0.000
O36.6 Maternal care for excessive foetal growth	0.093	0.907	0.000
O36.9 Maternal care for foetal problem, unspecified	0.093	0.907	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.087	0.913	0.000
O36.4 Maternal care for intra-uterine death	0.086	0.914	0.000
O43 Placental disorders	0.080	0.920	0.000
O30 Multiple gestation	0.078	0.922	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.076	0.924	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.076	0.924	0.000
O48 Prolonged pregnancy	0.075	0.925	0.000
O60-O75 Complications of labour and delivery	0.074	0.926	0.000
O36.1 Maternal care for other isoimmunisation	0.074	0.926	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.073	0.927	0.000
O30.0 Twin pregnancy	0.073	0.927	0.000
O33 Maternal care for known or suspected disproportion	0.073	0.927	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.072	0.928	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.071	0.929	0.000
O43.8 Other placental disorders	0.070	0.930	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.070	0.930	0.000
O36.2 Maternal care for hydrops foetalis	0.070	0.930	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.069	0.931	0.000
O41 Other disorders of amniotic fluid and membranes	0.069	0.931	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.069	0.931	0.000
O36.5 Maternal care for poor foetal growth	0.068	0.932	0.000
O62 Abnormalities of forces of labour	0.068	0.932	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.067	0.933	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.067	0.933	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.066	0.934	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.064	0.936	0.000
O43.1 Malformation of placenta	0.063	0.937	0.000
O31 Complications specific to multiple gestation	0.062	0.938	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.062	0.938	0.000
O43.9 Placental disorder, unspecified	0.062	0.938	0.000
O47 False labour	0.062	0.938	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.062	0.938	0.000
O62.2 Other uterine inertia	0.060	0.940	0.000
O66 Other obstructed labour	0.060	0.940	0.000
O72 Postpartum haemorrhage	0.060	0.940	0.000
O43.0 Placental transfusion syndromes	0.059	0.940	0.000
O33.9 Maternal care for disproportion, unspecified	0.059	0.941	0.000
O45 Premature separation of placenta [abruptio placentae]	0.059	0.941	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.059	0.941	0.000
O62.3 Precipitate labour	0.059	0.941	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.059	0.941	0.000
E10.9 Without complications	0.059	0.941	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.058	0.942	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.058	0.942	0.000
O16 Unspecified maternal hypertension	0.058	0.942	0.000
O43.2 Morbidly adherent placenta	0.057	0.943	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.057	0.943	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.056	0.943	0.000
O74 Complications of anaesthesia during labour and delivery	0.056	0.943	0.000
O30.9 Multiple gestation, unspecified	0.056	0.943	0.000
O30.8 Other multiple gestation	0.056	0.943	0.000
O30.2 Quadruplet pregnancy	0.056	0.943	0.000
O30.1 Triplet pregnancy	0.056	0.943	0.000
O85-O92 Complications predominantly related to the puerperium	0.056	0.944	0.000
O47.9 False labour, unspecified	0.056	0.944	0.000
O72.1 Other immediate postpartum haemorrhage	0.055	0.945	0.000
E10.1 With ketoacidosis	0.055	0.945	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.054	0.946	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.054	0.946	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.053	0.947	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.053	0.947	0.000
O60 Preterm delivery	0.053	0.947	0.000
O44 Placenta praevia	0.053	0.947	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.053	0.947	0.000
O33.8 Maternal care for disproportion of other origin	0.052	0.948	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.052	0.948	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.052	0.948	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.052	0.948	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.052	0.948	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.052	0.948	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.052	0.948	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.052	0.948	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.052	0.948	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.051	0.949	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.051	0.949	0.000
O69.3 Labour and delivery complicated by short cord	0.051	0.949	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.051	0.949	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.051	0.949	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.050	0.950	0.000
O46.9 Antepartum haemorrhage, unspecified	0.050	0.950	0.000
O41.1 Infection of amniotic sac and membranes	0.049	0.950	0.000
O62.9 Abnormality of forces of labour, unspecified	0.049	0.951	0.000
O62.8 Other abnormalities of forces of labour	0.049	0.951	0.000
O61 Failed induction of labour	0.049	0.951	0.000
O73 Retained placenta and membranes, without haemorrhage	0.048	0.952	0.000
O34.3 Maternal care for cervical incompetence	0.048	0.952	0.000
O90 Complications of the puerperium, not elsewhere classified	0.048	0.952	0.000
O15 Eclampsia	0.048	0.952	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.048	0.952	0.000
O66.2 Obstructed labour due to unusually large foetus	0.048	0.952	0.000
O34.4 Maternal care for other abnormalities of cervix	0.047	0.952	0.000
O69.8 Labour and delivery complicated by other cord complications	0.047	0.953	0.000
O36.8 Maternal care for other specified foetal problems	0.047	0.953	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.046	0.954	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.046	0.954	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.046	0.954	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.046	0.954	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.046	0.954	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.046	0.954	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.046	0.954	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.046	0.954	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.046	0.954	0.000
O31.8 Other complications specific to multiple gestation	0.045	0.955	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.045	0.955	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.045	0.955	0.000
O31.0 Papyraceous foetus	0.045	0.955	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.045	0.955	0.000
O62.1 Secondary uterine inertia	0.045	0.955	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.044	0.956	0.000
O66.4 Failed trial of labour, unspecified	0.044	0.956	0.000
O40 Polyhydramnios	0.044	0.956	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.044	0.956	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.044	0.956	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.044	0.956	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.043	0.957	0.000
O66.9 Obstructed labour, unspecified	0.043	0.957	0.000
O66.8 Other specified obstructed labour	0.043	0.957	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.043	0.957	0.000
O66.1 Obstructed labour due to locked twins	0.043	0.957	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.043	0.957	0.000
O72.3 Postpartum coagulation defects	0.043	0.957	0.000
O85 Puerperal sepsis	0.043	0.957	0.000
O45.8 Other premature separation of placenta	0.043	0.957	0.000
O45.0 Premature separation of placenta with coagulation defect	0.043	0.957	0.000
O89 Complications of anaesthesia during the puerperium	0.043	0.957	0.000
O12.1 Gestational proteinuria	0.043	0.957	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.042	0.958	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.042	0.958	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.042	0.958	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.042	0.958	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.042	0.958	0.000
O65.0 Obstructed labour due to deformed pelvis	0.042	0.958	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.042	0.958	0.000
O34.6 Maternal care for abnormality of vagina	0.042	0.958	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.042	0.958	0.000
O34.0 Maternal care for congenital malformation of uterus	0.042	0.958	0.000
O64.2 Obstructed labour due to face presentation	0.042	0.958	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.042	0.958	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.042	0.958	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.041	0.959	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.041	0.959	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.041	0.959	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.041	0.959	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.041	0.959	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.041	0.959	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.041	0.959	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.041	0.959	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.041	0.959	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.041	0.959	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.041	0.959	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.041	0.959	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.040	0.960	0.000
O91 Infections of breast associated with childbirth	0.040	0.960	0.000
O88 Obstetric embolism	0.040	0.960	0.000
O45.9 Premature separation of placenta, unspecified	0.040	0.960	0.000
O90.2 Haematoma of obstetric wound	0.039	0.961	0.000
O71 Other obstetric trauma	0.039	0.961	0.000
O97 Death from sequelae of direct obstetric causes	0.038	0.961	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.038	0.961	0.000
O95 Obstetric death of unspecified cause	0.038	0.961	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.038	0.961	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.038	0.962	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.038	0.962	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.038	0.962	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.038	0.962	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.038	0.962	0.000
O62.0 Primary inadequate contractions	0.038	0.962	0.000
O60.3 Preterm delivery without spontaneous labour	0.038	0.962	0.000
O60.2 Preterm spontaneous labour with term delivery	0.038	0.962	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.038	0.962	0.000
O60.0 Preterm labour without delivery	0.038	0.962	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.038	0.962	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.038	0.962	0.000
O12.2 Gestational oedema with proteinuria	0.038	0.962	0.000
O90.9 Complication of the puerperium, unspecified	0.037	0.963	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.037	0.963	0.000
O87 Venous complications in the puerperium	0.037	0.963	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.037	0.963	0.000
O64.5 Obstructed labour due to compound presentation	0.037	0.963	0.000
O64.4 Obstructed labour due to shoulder presentation	0.037	0.963	0.000
O64.3 Obstructed labour due to brow presentation	0.037	0.963	0.000
O46.8 Other antepartum haemorrhage	0.037	0.963	0.000
O90.0 Disruption of Caesarean section wound	0.037	0.963	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.036	0.964	0.000
O34.1 Maternal care for tumour of corpus uteri	0.036	0.964	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.036	0.964	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.035	0.964	0.000
O61.9 Failed induction of labour, unspecified	0.035	0.965	0.000
O61.8 Other failed induction of labour	0.035	0.965	0.000
O61.1 Failed instrumental induction of labour	0.035	0.965	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.035	0.965	0.000
O75.8 Other specified complications of labour and delivery	0.035	0.965	0.000
O90.5 Postpartum thyroiditis	0.034	0.965	0.000
O90.4 Postpartum acute renal failure	0.034	0.965	0.000
O90.3 Cardiomyopathy in the puerperium	0.034	0.965	0.000
O15.9 Eclampsia, unspecified as to time period	0.034	0.965	0.000
O15.2 Eclampsia in the puerperium	0.034	0.965	0.000
O15.1 Eclampsia in labour	0.034	0.965	0.000
O15.0 Eclampsia in pregnancy	0.034	0.965	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.034	0.966	0.000
O72.0 Third-stage haemorrhage	0.034	0.966	0.000
O47.0 False labour before 37 completed weeks of gestation	0.033	0.966	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.033	0.966	0.000
O70 Perineal laceration during delivery	0.033	0.967	0.000
O90.1 Disruption of perineal obstetric wound	0.033	0.967	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.033	0.967	0.000
O73.0 Retained placenta, without haemorrhage	0.033	0.967	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.032	0.968	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.032	0.968	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.032	0.968	0.000
O44.1 Placenta praevia with haemorrhage	0.032	0.968	0.000
O86 Other puerperal infections	0.032	0.968	0.000
O12.0 Gestational oedema	0.032	0.968	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.032	0.968	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.032	0.968	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.031	0.968	0.000
O61.0 Failed medical induction of labour	0.031	0.969	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.031	0.969	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.031	0.969	0.000
O89.6 Failed or difficult intubation during the puerperium	0.031	0.969	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.031	0.969	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.031	0.969	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.031	0.969	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.031	0.969	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.031	0.969	0.000
O80-O84 Delivery	0.031	0.969	0.000
O64.1 Obstructed labour due to breech presentation	0.031	0.969	0.000
O14.1 Severe preeclampsia	0.031	0.969	0.000
O41.0 Oligohydramnios	0.030	0.969	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.030	0.970	0.000
O87.8 Other venous complications in the puerperium	0.030	0.970	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.030	0.970	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.030	0.970	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.030	0.970	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.030	0.970	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.030	0.970	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.030	0.970	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.030	0.970	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.030	0.970	0.000
O14.2 HELLP syndrome	0.030	0.970	0.000
O63 Long labour	0.030	0.970	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.030	0.970	0.000
O75.9 Complication of labour and delivery, unspecified	0.030	0.970	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.030	0.970	0.000
O75.4 Other complications of obstetric surgery and procedures	0.030	0.970	0.000
O75.3 Other infection during labour	0.030	0.970	0.000
O75.1 Shock during or following labour and delivery	0.030	0.970	0.000
O67.8 Other intrapartum haemorrhage	0.029	0.970	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.029	0.970	0.000
A41 Other septicaemia	0.029	0.971	0.000
O14.0 Moderate preeclampsia	0.029	0.971	0.000
O88.8 Other obstetric embolism	0.029	0.971	0.000
O88.3 Obstetric pyaemic and septic embolism	0.029	0.971	0.000
O88.2 Obstetric blood-clot embolism	0.029	0.971	0.000
O88.1 Amniotic fluid embolism	0.029	0.971	0.000
O88.0 Obstetric air embolism	0.029	0.971	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.029	0.971	0.000
O91.1 Abscess of breast associated with childbirth	0.029	0.971	0.000
O91.0 Infection of nipple associated with childbirth	0.029	0.971	0.000
E87.7 Fluid overload	0.029	0.971	0.000
O92.1 Cracked nipple associated with childbirth	0.029	0.971	0.000
O70.2 Third degree perineal laceration during delivery	0.029	0.971	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.029	0.971	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.028	0.972	0.000
E70-E90 Metabolic disorders	0.028	0.972	0.000
O71.7 Obstetric haematoma of pelvis	0.028	0.972	0.000
O71.9 Obstetric trauma, unspecified	0.028	0.972	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.028	0.972	0.000
O71.5 Other obstetric injury to pelvic organs	0.028	0.972	0.000
O71.3 Obstetric laceration of cervix	0.028	0.972	0.000
O71.2 Postpartum inversion of uterus	0.028	0.972	0.000
O71.1 Rupture of uterus during labour	0.028	0.972	0.000
O71.0 Rupture of uterus before onset of labour	0.028	0.972	0.000
A41.8 Other specified septicaemia	0.028	0.972	0.000
O96.9 Death from unspecified obstetric cause	0.028	0.972	0.000
O96.1 Death from indirect obstetric cause	0.028	0.972	0.000
O96.0 Death from direct obstetric cause	0.028	0.972	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.028	0.972	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.028	0.972	0.000
O97.0 Death from sequelae of direct obstetric cause	0.028	0.972	0.000
E87.5 Hyperkalaemia	0.028	0.972	0.000
E88 Other metabolic disorders	0.028	0.972	0.000
O92.7 Other and unspecified disorders of lactation	0.027	0.972	0.000
O92.6 Galactorrhoea	0.027	0.972	0.000
O92.5 Suppressed lactation	0.027	0.972	0.000
O92.4 Hypogalactia	0.027	0.972	0.000
O92.3 Agalactia	0.027	0.972	0.000
O92.0 Retracted nipple associated with childbirth	0.027	0.972	0.000
Z37.2 Twins, both liveborn	0.027	0.973	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.027	0.973	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.027	0.973	0.000
O70.3 Fourth degree perineal laceration during delivery	0.027	0.973	0.000
O71.8 Other specified obstetric trauma	0.027	0.973	0.000
O87.9 Venous complication in the puerperium, unspecified	0.027	0.973	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.027	0.973	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.027	0.973	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.027	0.973	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.027	0.973	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.027	0.973	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.026	0.974	0.000
A41.9 Septicaemia, unspecified	0.026	0.974	0.000
E87.3 Alkalosis	0.026	0.974	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.026	0.974	0.000
O75.0 Maternal distress during labour and delivery	0.025	0.975	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.025	0.975	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.025	0.975	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.025	0.975	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.025	0.975	0.000
I35.0 Aortic (valve) stenosis	0.025	0.975	0.000
E85 Amyloidosis	0.025	0.975	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.025	0.975	0.000
E40-E46 Malnutrition	0.024	0.976	0.000
O14.9 Preeclampsia, unspecified	0.024	0.976	0.000
I35 Nonrheumatic aortic valve disorders	0.024	0.976	0.000
O81 Single delivery by forceps and vacuum extractor	0.024	0.976	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.023	0.977	0.000
O86.8 Other specified puerperal infections	0.023	0.977	0.000
O86.3 Other genito-urinary tract infections following delivery	0.023	0.977	0.000
O86.2 Urinary tract infection following delivery	0.023	0.977	0.000
E87.0 Hyperosmolality and hypernatraemia	0.023	0.977	0.000
Z37 Outcome of delivery	0.023	0.977	0.000
O86.1 Other infection of genital tract following delivery	0.023	0.977	0.000
E88.2 Lipomatosis, not elsewhere classified	0.023	0.977	0.000
E87.6 Hypokalaemia	0.022	0.978	0.000
O84 Multiple delivery	0.022	0.978	0.000
O83 Other assisted single delivery	0.022	0.978	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.022	0.978	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.022	0.978	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.022	0.978	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.022	0.978	0.000
E87.4 Mixed disorder of acid-base balance	0.022	0.978	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.022	0.978	0.000
Z37.1 Single stillbirth	0.022	0.978	0.000
I35.9 Aortic valve disorder, unspecified	0.022	0.978	0.000
Z04.8 Examination and observation for other specified reasons	0.022	0.978	0.000
O70.9 Perineal laceration during delivery, unspecified	0.021	0.979	0.000
E79 Disorders of purine and pyrimidine metabolism	0.021	0.979	0.000
A41.4 Septicaemia due to anaerobes	0.021	0.979	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.021	0.979	0.000
J84 Other interstitial pulmonary diseases	0.021	0.979	0.000
O86.4 Pyrexia of unknown origin following delivery	0.021	0.979	0.000
E84 Cystic fibrosis	0.021	0.979	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.021	0.979	0.000
E77 Disorders of glycoprotein metabolism	0.021	0.979	0.000
E76 Disorders of glycosaminoglycan metabolism	0.021	0.979	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.021	0.979	0.000
E72 Other disorders of amino-acid metabolism	0.021	0.979	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.021	0.979	0.000
E70 Disorders of aromatic amino-acid metabolism	0.021	0.979	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.021	0.979	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.021	0.979	0.000
O42 Premature rupture of membranes	0.020	0.980	0.000
E85.4 Organ-limited amyloidosis	0.020	0.980	0.000
E88.9 Metabolic disorder, unspecified	0.020	0.980	0.000
E88.3 Tumour lysis syndrome	0.020	0.980	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.020	0.980	0.000
O81.4 Vacuum extractor delivery	0.020	0.980	0.000
Z35 Supervision of high-risk pregnancy	0.020	0.980	0.000
E85.3 Secondary systemic amyloidosis	0.020	0.980	0.000
O22 Venous complications in pregnancy	0.020	0.980	0.000
J80 Adult respiratory distress syndrome	0.020	0.980	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.019	0.981	0.000
E87.2 Acidosis	0.019	0.981	0.000
E88.8 Other specified metabolic disorders	0.019	0.981	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.019	0.981	0.000
E74 Other disorders of carbohydrate metabolism	0.019	0.981	0.000
L29.0 Pruritus ani	0.019	0.981	0.000
O86.0 Infection of obstetric surgical wound	0.019	0.981	0.000
E80.1 Porphyria cutanea tarda	0.019	0.981	0.000
E85.9 Amyloidosis, unspecified	0.019	0.981	0.000
O28 Abnormal findings on antenatal screening of mother	0.019	0.981	0.000
O63.0 Prolonged first stage (of labour)	0.019	0.981	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.018	0.981	0.000
O63.9 Long labour, unspecified	0.019	0.981	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.018	0.981	0.000
E46 Unspecified protein-energy malnutrition	0.018	0.981	0.000
O24 Diabetes mellitus in pregnancy	0.018	0.982	0.000
O20 Haemorrhage in early pregnancy	0.018	0.982	0.000
O29 Complications of anaesthesia during pregnancy	0.018	0.982	0.000
O25 Malnutrition in pregnancy	0.018	0.982	0.000
E50-E64 Other nutritional deficiencies	0.018	0.982	0.000
E85.8 Other amyloidosis	0.018	0.982	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.018	0.982	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.018	0.982	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.018	0.982	0.000
Z37.3 Twins, one liveborn and one stillborn	0.018	0.982	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.017	0.982	0.000
E45 Retarded development following protein-energy malnutrition	0.017	0.982	0.000
E43 Unspecified severe protein-energy malnutrition	0.017	0.982	0.000
E42 Marasmic kwashiorkor	0.017	0.982	0.000
E41 Nutritional marasmus	0.017	0.982	0.000
E40 Kwashiorkor	0.017	0.982	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.018	0.982	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.018	0.982	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.017	0.982	0.000
O82 Single delivery by Caesarean section	0.017	0.983	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.017	0.983	0.001
O81.5 Delivery by combination of forceps and vacuum extractor	0.017	0.983	0.000
O81.2 Mid-cavity forceps with rotation	0.017	0.983	0.000
O81.1 Mid-cavity forceps delivery	0.017	0.983	0.000
O87.2 Haemorrhoids in the puerperium	0.017	0.983	0.001
E80.2 Other porphyria	0.017	0.983	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.017	0.983	0.000
E73 Lactose intolerance	0.017	0.983	0.000
U88 Agent resistant to multiple antibiotics	0.017	0.983	0.000
Z35.8 Supervision of other high-risk pregnancies	0.017	0.983	0.000
I35.8 Other aortic valve disorders	0.017	0.983	0.000
Z37.9 Outcome of delivery unspecified	0.017	0.983	0.000
Z37.7 Other multiple births, all stillborn	0.017	0.983	0.000
Z37.6 Other multiple births, some liveborn	0.017	0.983	0.000
Z37.5 Other multiple births, all liveborn	0.017	0.983	0.000
Z37.4 Twins, both stillborn	0.017	0.983	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.017	0.983	0.000
O22.4 Haemorrhoids in pregnancy	0.016	0.984	0.000
O83.9 Assisted single delivery, unspecified	0.016	0.984	0.000
O83.8 Other specified assisted single delivery	0.016	0.984	0.000
O83.4 Destructive operation for delivery	0.016	0.984	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.016	0.984	0.000
O83.2 Other manipulation-assisted delivery	0.016	0.984	0.000
O83.1 Other assisted breech delivery	0.016	0.984	0.000
O83.0 Breech extraction	0.016	0.984	0.000
O84.9 Multiple delivery, unspecified	0.016	0.984	0.000
O84.8 Other multiple delivery	0.016	0.984	0.000
O84.2 Multiple delivery, all by Caesarean section	0.016	0.984	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.016	0.984	0.000
O84.0 Multiple delivery, all spontaneous	0.016	0.984	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.016	0.984	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.016	0.984	0.000
O81.0 Low forceps delivery	0.016	0.984	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.016	0.984	0.000
E80.5 Crigler-Najjar syndrome	0.016	0.984	0.000
E80.3 Defects of catalase and peroxydase	0.016	0.984	0.000
E80.0 Hereditary erythropoietic porphyria	0.016	0.984	0.000
Z01.8 Other specified special examinations	0.016	0.984	0.000
O81.3 Other and unspecified forceps delivery	0.016	0.984	0.000
O32.3 Maternal care for face, brow and chin presentation	0.016	0.984	0.000
O32.6 Maternal care for compound presentation	0.016	0.984	0.000
Z04 Examination and observation for other reasons	0.016	0.984	0.000
I35.1 Aortic (valve) insufficiency	0.016	0.984	0.000
O71.4 Obstetric high vaginal laceration alone	0.015	0.984	0.001
J69 Pneumonitis due to solids and liquids	0.016	0.984	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.016	0.984	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.015	0.984	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations