TreeWAS – Variant ID: rs2251219

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F31 Bipolar affective disorder	0.000	0.150	0.850
F31.9 Bipolar affective disorder, unspecified	0.000	0.151	0.849
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.195	0.805
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.227	0.773
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.232	0.768
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.240	0.760
F31.7 Bipolar affective disorder, currently in remission	0.000	0.299	0.701
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.365	0.635
F31.8 Other bipolar affective disorders	0.000	0.369	0.631
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.378	0.622
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.394	0.606
F30-F39 Mood [affective] disorders	0.000	0.589	0.411
M16.1 Other primary coxarthrosis	0.404	0.596	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.400	0.600	0.000
M16 Coxarthrosis [arthrosis of hip]	0.397	0.603	0.000
M18 Arthrosis of first carpometacarpal joint	0.397	0.603	0.000
M16.9 Coxarthrosis, unspecified	0.381	0.619	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.373	0.627	0.000
M15-M19 Arthrosis	0.371	0.629	0.000
F34 Persistent mood [affective] disorders	0.000	0.657	0.342
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.328	0.672	0.000
F30 Manic episode	0.000	0.682	0.318
F32 Depressive episode	0.000	0.689	0.311
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.303	0.697	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.303	0.697	0.000
F34.1 Dysthymia	0.000	0.700	0.300
F38 Other mood [affective] disorders	0.000	0.705	0.295
M16.6 Other secondary coxarthrosis, bilateral	0.286	0.714	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.285	0.715	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.284	0.715	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.284	0.715	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.284	0.715	0.000
M16.3 Other dysplastic coxarthrosis	0.280	0.720	0.000
F32.1 Moderate depressive episode	0.000	0.721	0.279
F30.0 Hypomania	0.000	0.728	0.272
M16.0 Primary coxarthrosis, bilateral	0.264	0.736	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.736	0.264
M16.5 Other posttraumatic coxarthrosis	0.249	0.751	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.754	0.246
F34.8 Other persistent mood [affective] disorders	0.000	0.754	0.246
F39 Unspecified mood [affective] disorder	0.000	0.754	0.245
F34.0 Cyclothymia	0.000	0.768	0.232
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.768	0.232
F30.2 Mania with psychotic symptoms	0.000	0.771	0.229
F30.8 Other manic episodes	0.000	0.772	0.228
F33 Recurrent depressive disorder	0.000	0.777	0.223
M16.7 Other secondary coxarthrosis	0.223	0.777	0.000
F30.9 Manic episode, unspecified	0.000	0.781	0.219
F32.8 Other depressive episodes	0.000	0.782	0.218
F38.8 Other specified mood [affective] disorders	0.000	0.788	0.211
F38.1 Other recurrent mood [affective] disorders	0.000	0.788	0.211
F38.0 Other single mood [affective] disorders	0.000	0.788	0.211
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.799	0.201
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.801	0.199
F30.1 Mania without psychotic symptoms	0.000	0.802	0.198
F32.0 Mild depressive episode	0.000	0.803	0.197
F33.9 Recurrent depressive disorder, unspecified	0.000	0.822	0.178
M15 Polyarthrosis	0.177	0.822	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.842	0.158
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.844	0.156
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.155	0.845	0.000
M05-M14 Inflammatory polyarthropathies	0.154	0.846	0.000
M15.8 Other polyarthrosis	0.152	0.848	0.000
M06 Other rheumatoid arthritis	0.151	0.849	0.000
Z36 Antenatal screening	0.148	0.852	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.148	0.852	0.000
M80-M85 Disorders of bone density and structure	0.147	0.853	0.000
C43 Malignant melanoma of skin	0.000	0.854	0.146
M05 Seropositive rheumatoid arthritis	0.145	0.855	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.145	0.855	0.000
M81 Osteoporosis without pathological fracture	0.145	0.855	0.000
F33.8 Other recurrent depressive disorders	0.000	0.856	0.144
M81.4 Drug-induced osteoporosis	0.142	0.857	0.000
M06.3 Rheumatoid nodule	0.142	0.858	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.141	0.859	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.138	0.862	0.000
M87 Osteonecrosis	0.138	0.862	0.000
M86-M90 Other osteopathies	0.136	0.863	0.000
M87.9 Osteonecrosis, unspecified	0.136	0.864	0.000
S32.50 Fracture of pubis (closed)	0.134	0.866	0.000
M06.34 Rheumatoid nodule (Hand)	0.133	0.867	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.133	0.867	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.132	0.868	0.000
M15.3 Secondary multiple arthrosis	0.131	0.868	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.132	0.868	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.131	0.869	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.130	0.870	0.000
M06.9 Rheumatoid arthritis, unspecified	0.130	0.870	0.000
M15.0 Primary generalised (osteo)arthrosis	0.130	0.870	0.000
M85 Other disorders of bone density and structure	0.127	0.873	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.874	0.126
M15.9 Polyarthrosis, unspecified	0.125	0.875	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.875	0.125
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.124	0.876	0.000
S32.5 Fracture of pubis	0.123	0.877	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.123	0.877	0.000
M12 Other specific arthropathies	0.122	0.878	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.121	0.879	0.000
Z36.8 Other antenatal screening	0.120	0.880	0.000
M06.0 Seronegative rheumatoid arthritis	0.120	0.880	0.000
M00-M03 Infectious arthropathies	0.119	0.881	0.000
M05.2 Rheumatoid vasculitis	0.117	0.883	0.000
M11 Other crystal arthropathies	0.116	0.884	0.000
S32 Fracture of lumbar spine and pelvis	0.116	0.884	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.886	0.114
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.114	0.886	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.113	0.887	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.112	0.888	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.112	0.888	0.000
S32.4 Fracture of acetabulum	0.111	0.889	0.000
M81.8 Other osteoporosis	0.111	0.889	0.000
M06.8 Other specified rheumatoid arthritis	0.111	0.889	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.111	0.889	0.000
M08 Juvenile arthritis	0.111	0.889	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.110	0.889	0.000
M85.6 Other cyst of bone	0.110	0.890	0.000
M81.9 Osteoporosis, unspecified	0.110	0.890	0.000
M87.8 Other osteonecrosis	0.110	0.890	0.000
S32.40 Fracture of acetabulum (closed)	0.109	0.891	0.000
H25.8 Other senile cataract	0.000	0.891	0.109
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.108	0.892	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.108	0.892	0.000
M81.0 Postmenopausal osteoporosis	0.108	0.892	0.000
M06.2 Rheumatoid bursitis	0.108	0.892	0.000
M06.1 Adult-onset Still's disease	0.108	0.892	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.107	0.893	0.000
M87.2 Osteonecrosis due to previous trauma	0.107	0.893	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.107	0.893	0.000
M80 Osteoporosis with pathological fracture	0.107	0.893	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.107	0.893	0.000
M99 Biomechanical lesions, not elsewhere classified	0.107	0.893	0.000
M60-M63 Disorders of muscles	0.107	0.893	0.000
Z36.5 Antenatal screening for isoimmunisation	0.106	0.893	0.000
M87.1 Osteonecrosis due to drugs	0.106	0.893	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.106	0.894	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.105	0.894	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.895	0.105
C43.0 Malignant melanoma of lip	0.000	0.895	0.105
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.104	0.895	0.000
M05.0 Felty's syndrome	0.104	0.895	0.000
M91-M94 Chondropathies	0.105	0.895	0.000
M06.4 Inflammatory polyarthropathy	0.104	0.896	0.000
M81.6 Localised osteoporosis [Lequesne]	0.104	0.896	0.000
M81.5 Idiopathic osteoporosis	0.104	0.896	0.000
M81.1 Postoophorectomy osteoporosis	0.104	0.896	0.000
M85.2 Hyperostosis of skull	0.103	0.897	0.000
M10 Gout	0.103	0.897	0.000
M81.48 Drug-induced osteoporosis (Other)	0.102	0.898	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.102	0.898	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.102	0.898	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.102	0.898	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.102	0.898	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.102	0.898	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.102	0.898	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.102	0.898	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.102	0.898	0.000
M83 Adult osteomalacia	0.102	0.898	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.102	0.898	0.000
M06.38 Rheumatoid nodule (Other)	0.102	0.898	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.102	0.898	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.102	0.898	0.000
M06.33 Rheumatoid nodule (Forearm)	0.102	0.898	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.102	0.898	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.101	0.899	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.101	0.899	0.000
M05.1 Rheumatoid lung disease	0.100	0.900	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.100	0.900	0.000
M05.8 Other seropositive rheumatoid arthritis	0.100	0.900	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.099	0.901	0.000
M14 Arthropathies in other diseases classified elsewhere	0.099	0.901	0.000
M87.3 Other secondary osteonecrosis	0.099	0.901	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.099	0.901	0.000
M45-M49 Spondylopathies	0.099	0.901	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.098	0.902	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.098	0.902	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.098	0.902	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.098	0.902	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.098	0.902	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.098	0.902	0.000
H25 Senile cataract	0.000	0.903	0.097
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.096	0.904	0.000
M85.0 Fibrous dysplasia (monostotic)	0.096	0.904	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.096	0.904	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.095	0.904	0.000
M12.3 Palindromic rheumatism	0.095	0.905	0.000
M00 Pyogenic arthritis	0.095	0.905	0.000
M82 Osteoporosis in diseases classified elsewhere	0.095	0.905	0.000
M15.4 Erosive (osteo)arthrosis	0.094	0.905	0.001
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.095	0.905	0.000
M12.5 Traumatic arthropathy	0.095	0.905	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.094	0.906	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.094	0.906	0.000
M81.2 Osteoporosis of disuse	0.094	0.906	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.093	0.907	0.000
H25.1 Senile nuclear cataract	0.000	0.907	0.093
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.092	0.908	0.000
S32.3 Fracture of ilium	0.092	0.908	0.000
M85.5 Aneurysmal bone cyst	0.091	0.909	0.000
M85.4 Solitary bone cyst	0.091	0.909	0.000
M85.3 Osteitis condensans	0.091	0.909	0.000
M85.1 Skeletal fluorosis	0.091	0.909	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.091	0.909	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.091	0.909	0.000
M81.98 Osteoporosis, unspecified (Other)	0.090	0.910	0.000
M10.0 Idiopathic gout	0.090	0.910	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.090	0.910	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.090	0.910	0.000
M11.2 Other chondrocalcinosis	0.090	0.910	0.000
S32.1 Fracture of sacrum	0.089	0.911	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.089	0.911	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.089	0.911	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.089	0.911	0.000
M48 Other spondylopathies	0.089	0.911	0.000
S32.51 Fracture of pubis (open)	0.088	0.911	0.000
M13 Other arthritis	0.089	0.911	0.000
H26.9 Cataract, unspecified	0.000	0.911	0.089
M99.5 Intervertebral disk stenosis of neural canal	0.088	0.912	0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.912	0.088
M15.99 Polyosteoarthritis, unspecified	0.088	0.912	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.912	0.088
M12.4 Intermittent hydrarthrosis	0.088	0.912	0.000
M12.1 Kaschin-Beck disease	0.088	0.912	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.088	0.912	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.087	0.912	0.000
M15.1 Heberden's nodes (with arthropathy)	0.087	0.912	0.001
M85.68 Other cyst of bone (Other)	0.087	0.913	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.087	0.913	0.000
M81.80 Other osteoporosis (Multiple sites)	0.087	0.913	0.000
H26 Other cataract	0.000	0.913	0.087
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.086	0.914	0.000
M85.20 Hyperostosis of skull-Mult sites	0.086	0.914	0.000
S32.0 Fracture of lumbar vertebra	0.086	0.914	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.086	0.914	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.086	0.914	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.086	0.914	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.086	0.914	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.086	0.914	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.085	0.914	0.000
H25-H28 Disorders of lens	0.000	0.915	0.085
H26.8 Other specified cataract	0.000	0.915	0.085
M85.8 Other specified disorders of bone density and structure	0.085	0.915	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.085	0.915	0.000
M92 Other juvenile osteochondrosis	0.085	0.915	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.084	0.915	0.000
M88 Paget's disease of bone [osteitis deformans]	0.084	0.915	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.084	0.916	0.000
M05.28 Rheumatoid vasculitis (Other)	0.084	0.916	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.084	0.916	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.084	0.916	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.084	0.916	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.084	0.916	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.084	0.916	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.084	0.916	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.084	0.916	0.000
M40-M43 Deforming dorsopathies	0.084	0.916	0.000
M85.66 Other cyst of bone (Lower leg)	0.084	0.916	0.000
M85.9 Disorder of bone density and structure, unspecified	0.084	0.916	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.083	0.916	0.000
M11.1 Familial chondrocalcinosis	0.083	0.917	0.000
M11.0 Hydroxyapatite deposition disease	0.083	0.917	0.000
S32.2 Fracture of coccyx	0.083	0.917	0.000
M11.9 Crystal arthropathy, unspecified	0.083	0.917	0.000
M02 Reactive arthropathies	0.083	0.917	0.000
M12.2 Villonodular synovitis (pigmented)	0.083	0.917	0.000
M07 Psoriatic and enteropathic arthropathies	0.083	0.917	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.083	0.917	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.918	0.082
M80.9 Unspecified osteoporosis with pathological fracture	0.082	0.918	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.082	0.918	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.082	0.918	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.082	0.918	0.000
M11.8 Other specified crystal arthropathies	0.082	0.918	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.082	0.918	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.082	0.918	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.081	0.919	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.081	0.919	0.000
M00.9 Pyogenic arthritis, unspecified	0.080	0.920	0.000
S32.41 Fracture of acetabulum (open)	0.080	0.920	0.000
M81.89 Other osteoporosis (Site unspecified)	0.080	0.920	0.000
M81.88 Other osteoporosis (Other)	0.080	0.920	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.080	0.920	0.000
M81.86 Other osteoporosis (Lower leg)	0.080	0.920	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.080	0.920	0.000
M81.84 Other osteoporosis (Hand)	0.080	0.920	0.000
M81.83 Other osteoporosis (Forearm)	0.080	0.920	0.000
M81.82 Other osteoporosis (Upper arm)	0.080	0.920	0.000
M81.81 Other osteoporosis (Shoulder region)	0.080	0.920	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.079	0.920	0.001
M06.88 Other specified rheumatoid arthritis (Other)	0.079	0.920	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.079	0.920	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.079	0.920	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.079	0.920	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.079	0.920	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.079	0.920	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.079	0.920	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.079	0.920	0.000
M08.9 Juvenile arthritis, unspecified	0.079	0.920	0.000
M08.8 Other juvenile arthritis	0.079	0.920	0.000
M08.4 Pauciarticular juvenile arthritis	0.079	0.920	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.079	0.920	0.000
M08.2 Juvenile arthritis with systemic onset	0.079	0.920	0.000
M08.1 Juvenile ankylosing spondylitis	0.079	0.920	0.000
M08.0 Juvenile rheumatoid arthritis	0.079	0.920	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.079	0.920	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.079	0.920	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.079	0.920	0.000
M09.0 Juvenile arthritis in psoriasis	0.079	0.920	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.079	0.920	0.000
M85.69 Other cyst of bone (Site unspecified)	0.079	0.921	0.000
M85.63 Other cyst of bone (Forearm)	0.079	0.921	0.000
M85.62 Other cyst of bone (Upper arm)	0.079	0.921	0.000
M85.61 Other cyst of bone (Shoulder region)	0.079	0.921	0.000
M85.60 Other cyst of bone (Multiple sites)	0.079	0.921	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.079	0.921	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.079	0.921	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.079	0.921	0.000
M87.88 Other osteonecrosis (Other)	0.079	0.921	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.079	0.921	0.000
M87.86 Other osteonecrosis (Lower leg)	0.079	0.921	0.000
M87.84 Other osteonecrosis (Hand)	0.079	0.921	0.000
M87.83 Other osteonecrosis (Forearm)	0.079	0.921	0.000
M87.82 Other osteonecrosis (Upper arm)	0.079	0.921	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.079	0.921	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.079	0.921	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.079	0.921	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.079	0.921	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.078	0.921	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.078	0.922	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.078	0.922	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.078	0.922	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.078	0.922	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.078	0.922	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.078	0.922	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.078	0.922	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.078	0.922	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.078	0.922	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.078	0.922	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.078	0.922	0.000
M06.18 Adult-onset Still's disease (Other)	0.078	0.922	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.078	0.922	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.078	0.922	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.078	0.922	0.000
M06.14 Adult-onset Still's disease (Hand)	0.078	0.922	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.078	0.922	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.078	0.922	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.078	0.922	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.078	0.922	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.078	0.922	0.000
M06.28 Rheumatoid bursitis (Other)	0.078	0.922	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.078	0.922	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.078	0.922	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.078	0.922	0.000
M06.24 Rheumatoid bursitis (Hand)	0.078	0.922	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.078	0.922	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.078	0.922	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.078	0.922	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.078	0.922	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.077	0.923	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.077	0.923	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.077	0.923	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.077	0.923	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.077	0.923	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.077	0.923	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.077	0.923	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.077	0.923	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.077	0.923	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.077	0.923	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.077	0.923	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.077	0.923	0.000
M99.9 Biomechanical lesion, unspecified	0.077	0.923	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.077	0.923	0.000
M99.4 Connective tissue stenosis of neural canal	0.077	0.923	0.000
M99.3 Osseous stenosis of neural canal	0.077	0.923	0.000
M99.2 Subluxation stenosis of neural canal	0.077	0.923	0.000
M99.1 Subluxation complex (vertebral)	0.077	0.923	0.000
M99.0 Segmental and somatic dysfunction	0.077	0.923	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.077	0.923	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.077	0.923	0.000
M61 Calcification and ossification of muscle	0.077	0.923	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.077	0.923	0.000
M99.8 Other biomechanical lesions	0.077	0.923	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.076	0.923	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.076	0.923	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.076	0.923	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.076	0.923	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.076	0.923	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.076	0.923	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.076	0.923	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.076	0.923	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.076	0.923	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.076	0.924	0.000
M83.1 Senile osteomalacia	0.076	0.924	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.076	0.924	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.076	0.924	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.076	0.924	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.076	0.924	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.076	0.924	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.076	0.924	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.076	0.924	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.076	0.924	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.076	0.924	0.000
M13.8 Other specified arthritis	0.076	0.924	0.000
M95.2 Other acquired deformity of head	0.075	0.925	0.000
M12.57 Traumatic arthropathy (Ankle and foot)	0.075	0.925	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.075	0.925	0.000
M05.09 Felty's syndrome (Site unspecified)	0.075	0.925	0.000
M05.08 Felty's syndrome (Other)	0.075	0.925	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.075	0.925	0.000
M05.06 Felty's syndrome (Lower leg)	0.075	0.925	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.075	0.925	0.000
M05.04 Felty's syndrome (Hand)	0.075	0.925	0.000
M05.03 Felty's syndrome (Forearm)	0.075	0.925	0.000
M05.02 Felty's syndrome (Upper arm)	0.075	0.925	0.000
M05.01 Felty's syndrome (Shoulder region)	0.075	0.925	0.000
M05.00 Felty's syndrome (Multiple sites)	0.075	0.925	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.075	0.925	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.075	0.925	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.075	0.925	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.075	0.925	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.075	0.925	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.075	0.925	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.075	0.925	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.075	0.925	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.075	0.925	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.075	0.925	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.075	0.925	0.000
M60 Myositis	0.075	0.925	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.075	0.925	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.075	0.925	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.075	0.925	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.075	0.925	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.075	0.925	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.075	0.925	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.075	0.925	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.075	0.925	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.075	0.925	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.075	0.925	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.075	0.925	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.075	0.925	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.075	0.925	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.075	0.925	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.075	0.925	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.075	0.925	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.075	0.925	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.075	0.925	0.000
M81.58 Idiopathic osteoporosis (Other)	0.075	0.925	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.075	0.925	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.075	0.925	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.075	0.925	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.075	0.925	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.075	0.925	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.075	0.925	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.075	0.925	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.075	0.925	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.075	0.925	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.075	0.925	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.075	0.925	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.075	0.925	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.075	0.925	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.075	0.925	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.075	0.925	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.075	0.925	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.075	0.925	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.075	0.925	0.000
S32.30 Fracture of ilium (closed)	0.075	0.925	0.000
M85.29 Hyperostosis of skull-Site unspec	0.074	0.926	0.000
M85.28 Hyperostosis of skull-Other	0.074	0.926	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.074	0.926	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.074	0.926	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.074	0.926	0.000
M85.24 Hyperostosis of skull-Hand	0.074	0.926	0.000
M85.23 Hyperostosis of skull-Forearm	0.074	0.926	0.000
M85.22 Hyperostosis of skull-Upper arm	0.074	0.926	0.000
M85.21 Hyperostosis of skull-Shldr region	0.074	0.926	0.000
M95.1 Cauliflower ear	0.074	0.926	0.000
M10.4 Other secondary gout	0.074	0.926	0.000
M10.3 Gout due to impairment of renal function	0.074	0.926	0.000
M10.2 Drug-induced gout	0.074	0.926	0.000
M10.1 Lead-induced gout	0.074	0.926	0.000
M62 Other disorders of muscle	0.074	0.926	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.074	0.926	0.000
M49 Spondylopathies in diseases classified elsewhere	0.074	0.926	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.074	0.926	0.000
M80.8 Other osteoporosis with pathological fracture	0.073	0.927	0.000
M45 Ankylosing spondylitis	0.073	0.927	0.000
M83.9 Adult osteomalacia, unspecified	0.073	0.927	0.000
M83.5 Other drug-induced osteomalacia in adults	0.073	0.927	0.000
M83.4 Aluminum bone disease	0.073	0.927	0.000
M83.3 Adult osteomalacia due to malnutrition	0.073	0.927	0.000
M83.2 Adult osteomalacia due to malabsorption	0.073	0.927	0.000
M83.0 Puerperal osteomalacia	0.073	0.927	0.000
M99.53 Intervertebral disc stenosis of neural canal (Lumbar region)	0.073	0.927	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.073	0.927	0.000
M86 Osteomyelitis	0.073	0.927	0.000
M92.6 Juvenile osteochondrosis of tarsus	0.072	0.927	0.000
M48.8 Other specified spondylopathies	0.072	0.928	0.000
M05.18 Rheumatoid lung disease (Other)	0.072	0.928	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.072	0.928	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.072	0.928	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.072	0.928	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations