TreeWAS – Variant ID: rs225190

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z95.3 Presence of xenogenic heart valve	0.021	0.979	0.000
Z95.4 Presence of other heart-valve replacement	0.021	0.979	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.019	0.981	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.018	0.982	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.017	0.983	0.000
Z95.2 Presence of prosthetic heart valve	0.017	0.983	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.984	0.016
Z95.0 Presence of cardiac pacemaker	0.014	0.986	0.000
N62 Hypertrophy of breast	0.014	0.986	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.988	0.012
T92.2 Sequelae of fracture at wrist and hand level	0.008	0.992	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.007
Y42.5 Other oestrogens and progestogens	0.007	0.993	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.993	0.007
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.007	0.993	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.007	0.993	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.007	0.993	0.000
O16 Unspecified maternal hypertension	0.000	0.993	0.007
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
Y42.7 Androgens and anabolic congeners	0.006	0.994	0.000
N20.1 Calculus of ureter	0.000	0.994	0.006
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.994	0.006
Y42.9 Other and unspecified hormone antagonists	0.006	0.994	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.006	0.994	0.000
Y42.2 Antithyroid drugs	0.006	0.994	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.994	0.005
Y42.1 Thyroid hormones and substitutes	0.005	0.995	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.995	0.005
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.995	0.005
G30 Alzheimer's disease	0.000	0.995	0.005
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O14.9 Preeclampsia, unspecified	0.000	0.995	0.005
M75.3 Calcific tendinitis of shoulder	0.000	0.995	0.005
M54.39 Sciatica (Site unspecified)	0.005	0.995	0.000
T92 Sequelae of injuries of upper limb	0.005	0.995	0.000
Y42.4 Oral contraceptives	0.005	0.995	0.000
O15 Eclampsia	0.000	0.995	0.005
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.004
O14.1 Severe preeclampsia	0.000	0.996	0.004
O14.0 Moderate preeclampsia	0.000	0.996	0.004
O14.2 HELLP syndrome	0.000	0.996	0.004
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.996	0.004
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.996	0.004
K35 Acute appendicitis	0.000	0.996	0.004
G30.1 Alzheimer's disease with late onset	0.000	0.996	0.004
G30.0 Alzheimer's disease with early onset	0.000	0.996	0.004
O36.6 Maternal care for excessive foetal growth	0.000	0.996	0.004
K51.8 Other ulcerative colitis	0.000	0.996	0.004
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.996	0.004
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.004	0.996	0.000
K35.3 Acute appendicitis with localized peritonitis	0.000	0.996	0.004
O15.9 Eclampsia, unspecified as to time period	0.000	0.996	0.003
O15.2 Eclampsia in the puerperium	0.000	0.996	0.003
O15.1 Eclampsia in labour	0.000	0.996	0.003
O15.0 Eclampsia in pregnancy	0.000	0.996	0.003
T92.4 Sequelae of injury of nerve of upper limb	0.004	0.996	0.000
O12.0 Gestational oedema	0.000	0.996	0.003
T92.9 Sequelae of unspecified injury of upper limb	0.003	0.996	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.004	0.996	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.996	0.003
S72.10 Pertrochanteric fracture (closed)	0.003	0.997	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.997	0.003
M84.06 Malunion of fracture (Lower leg)	0.003	0.997	0.000
M93.9 Osteochondropathy, unspecified	0.003	0.997	0.000
G30.8 Other Alzheimer's disease	0.000	0.997	0.003
G30-G32 Other degenerative diseases of the nervous system	0.000	0.997	0.003
T92.8 Sequelae of other specified injuries of upper limb	0.003	0.997	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.997	0.003
G31.0 Circumscribed brain atrophy	0.000	0.997	0.003
K75.8 Other specified inflammatory liver diseases	0.003	0.997	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
K86.2 Cyst of pancreas	0.000	0.997	0.003
M84.07 Malunion of fracture (Ankle and foot)	0.003	0.997	0.000
C85.0 Lymphosarcoma	0.000	0.997	0.003
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.003	0.997	0.000
T92.0 Sequelae of open wound of upper limb	0.003	0.997	0.000
M84.0 Malunion of fracture	0.003	0.997	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.997	0.003
O12.2 Gestational oedema with proteinuria	0.000	0.997	0.003
K70.4 Alcoholic hepatic failure	0.000	0.997	0.003
K35.8 Acute appendicitis, other and unspecified	0.000	0.997	0.003
K75.4 Autoimmune hepatitis	0.003	0.997	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.003	0.997	0.000
Q05.9 Spina bifida, unspecified	0.003	0.997	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.997	0.003
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.997	0.003
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.997	0.003
N85.4 Malposition of uterus	0.000	0.997	0.003
K75 Other inflammatory liver diseases	0.003	0.997	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.997	0.003
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.997	0.003
G31.8 Other specified degenerative diseases of nervous system	0.000	0.997	0.003
O12.1 Gestational proteinuria	0.000	0.997	0.003
M84.02 Malunion of fracture (Upper arm)	0.003	0.997	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.000	0.997	0.003
K75.0 Abscess of liver	0.003	0.997	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.997	0.003
H47.3 Other disorders of optic disk	0.000	0.997	0.003
S72.1 Pertrochanteric fracture	0.003	0.997	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.997	0.002
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.997	0.003
M31.6 Other giant cell arteritis	0.003	0.997	0.000
H52.3 Anisometropia and aniseikonia	0.000	0.997	0.003
M54.3 Sciatica	0.003	0.997	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.997	0.003
S43.0 Dislocation of shoulder joint	0.003	0.997	0.000
M54.37 Sciatica (Lumbosacral region)	0.002	0.997	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
K62.4 Stenosis of anus and rectum	0.002	0.998	0.000
G63.2 Diabetic polyneuropathy	0.000	0.998	0.002
N11 Chronic tubulo-interstitial nephritis	0.000	0.998	0.002
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
O36.9 Maternal care for foetal problem, unspecified	0.000	0.998	0.002
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
N11.1 Chronic obstructive pyelonephritis	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
K74.6 Other and unspecified cirrhosis of liver	0.002	0.998	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
K75.2 Nonspecific reactive hepatitis	0.002	0.998	0.000
K75.1 Phlebitis of portal vein	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.998	0.002
K75.3 Granulomatous hepatitis, not elsewhere classified	0.002	0.998	0.000
K51 Ulcerative colitis	0.000	0.998	0.002
Q05 Spina bifida	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.998	0.002
O36 Maternal care for other known or suspected foetal problems	0.000	0.998	0.002
S72.11 Pertrochanteric fracture (open)	0.002	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.000	0.998	0.002
Q05.4 Unspecified spina bifida with hydrocephalus	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
J81 Pulmonary oedema	0.000	0.998	0.002
M54.35 Sciatica (Thoracolumbar region)	0.002	0.998	0.000
M54.34 Sciatica-Thoracic	0.002	0.998	0.000
M54.33 Sciatica-Cervicothoracic	0.002	0.998	0.000
M54.32 Sciatica-Cervical	0.002	0.998	0.000
M54.31 Sciatica-Occipit-atl-axl	0.002	0.998	0.000
M54.30 Sciatica (Multiple sites in spine)	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.998	0.002
Q24.6 Congenital heart block	0.002	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
M93 Other osteochondropathies	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
K65.8 Other peritonitis	0.000	0.998	0.002
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.998	0.002
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.998	0.002
S72.3 Fracture of shaft of femur	0.002	0.998	0.000
K51.5 Mucosal proctocolitis	0.000	0.998	0.002
S70.9 Superficial injury of hip and thigh, unspecified	0.002	0.998	0.000
K74 Fibrosis and cirrhosis of liver	0.002	0.998	0.000
K51.4 Pseudopolyposis of colon	0.000	0.998	0.002
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.998	0.002
O36.1 Maternal care for other isoimmunisation	0.000	0.998	0.002
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.000	0.998	0.002
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.002	0.998	0.000
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
K73 Chronic hepatitis, not elsewhere classified	0.002	0.998	0.000
K74.1 Hepatic sclerosis	0.002	0.998	0.000
M93.1 Kienbock's disease of adults	0.002	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.998	0.002
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.998	0.002
S72 Fracture of femur	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.998	0.002
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.998	0.002
K73.9 Chronic hepatitis, unspecified	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
S72.31 Fracture of shaft of femur (open)	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
Y65.8 Other specified misadventures during surgical and medical care	0.002	0.998	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.002	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.002	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.002	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.000	0.998	0.002
O36.2 Maternal care for hydrops foetalis	0.000	0.998	0.002
Q05.7 Lumbar spina bifida without hydrocephalus	0.002	0.998	0.000
Q24.0 Dextrocardia	0.002	0.998	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
K73.2 Chronic active hepatitis, not elsewhere classified	0.002	0.998	0.000
Z51.8 Other specified medical care	0.000	0.998	0.002
K86 Other diseases of pancreas	0.000	0.998	0.002
K74.0 Hepatic fibrosis	0.002	0.998	0.000
M93.8 Other specified osteochondropathies	0.002	0.998	0.000
M93.2 Osteochondritis dissecans	0.002	0.998	0.000
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.002	0.998	0.000
K72 Hepatic failure, not elsewhere classified	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.998	0.002
O46.9 Antepartum haemorrhage, unspecified	0.000	0.998	0.002
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.002	0.998	0.000
K74.5 Biliary cirrhosis, unspecified	0.002	0.998	0.000
K74.4 Secondary biliary cirrhosis	0.002	0.998	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.002	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.998	0.002
K51.9 Ulcerative colitis, unspecified	0.000	0.998	0.002
O36.8 Maternal care for other specified foetal problems	0.000	0.998	0.002
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
S70.0 Contusion of hip	0.002	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M54.36 Sciatica (Lumbar region)	0.002	0.998	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.002	0.998	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.002	0.998	0.000
R90.0 Intracranial space-occupying lesion	0.002	0.998	0.000
K72.1 Chronic hepatic failure	0.002	0.998	0.000
I50.9 Heart failure, unspecified	0.002	0.998	0.000
R22.0 Localised swelling, mass and lump, head	0.002	0.998	0.000
S70 Superficial injury of hip and thigh	0.002	0.998	0.000
H52.2 Astigmatism	0.000	0.998	0.002
N03.9 Unspecified	0.000	0.998	0.002
S72.2 Subtrochanteric fracture	0.002	0.998	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.998	0.002
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.998	0.001
S72.7 Multiple fractures of femur	0.001	0.998	0.000
S72.4 Fracture of lower end of femur	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.001	0.998	0.000
S01.2 Open wound of nose	0.002	0.998	0.000
S79.8 Other specified injuries of hip and thigh	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.998	0.001
C12 Malignant neoplasm of pyriform sinus	0.002	0.998	0.000
K70-K77 Diseases of liver	0.002	0.998	0.000
M93.26 Osteochondritis dissecans knee	0.001	0.998	0.000
M93.86 Other specified osteochondropathies, lower leg	0.001	0.998	0.000
K74.3 Primary biliary cirrhosis	0.002	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.001	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.001	0.998	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.998	0.001
S72.8 Fractures of other parts of femur	0.001	0.998	0.000
Q25 Congenital malformations of great arteries	0.001	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.002	0.998	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
E22.1 Hyperprolactinaemia	0.000	0.998	0.001
I08.0 Disorders of both mitral and aortic valves	0.002	0.998	0.000
Q25.6 Stenosis of pulmonary artery	0.001	0.998	0.000
S72.9 Fracture of femur, part unspecified	0.001	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.001	0.998	0.000
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
K26.4 Chronic or unspecified with haemorrhage	0.002	0.998	0.000
R27.0 Ataxia, unspecified	0.001	0.998	0.000
T92.1 Sequelae of fracture of arm	0.001	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.001	0.999	0.000
I20.8 Other forms of angina pectoris	0.001	0.999	0.000
Q21.0 Ventricular septal defect	0.001	0.999	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.999	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.001	0.999	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.001	0.999	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.999	0.001
Q22.1 Congenital pulmonary valve stenosis	0.001	0.999	0.000
Q28 Other congenital malformations of circulatory system	0.001	0.999	0.000
S79 Other and unspecified injuries of hip and thigh	0.001	0.999	0.000
S72.21 Subtrochanteric fracture (open)	0.001	0.999	0.000
S72.41 Fracture of lower end of femur (open)	0.001	0.999	0.000
S72.71 Multiple fractures of femur (open)	0.001	0.999	0.000
K75.9 Inflammatory liver disease, unspecified	0.001	0.999	0.000
O72.0 Third-stage haemorrhage	0.000	0.999	0.001
Q23.0 Congenital stenosis of aortic valve	0.001	0.999	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.001	0.999	0.000
Q26.8 Other congenital malformations of great veins	0.001	0.999	0.000
Q26.6 Portal vein-hepatic artery fistula	0.001	0.999	0.000
Q26.5 Anomalous portal venous connexion	0.001	0.999	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.001	0.999	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.001	0.999	0.000
Q26.1 Persistent left superior vena cava	0.001	0.999	0.000
Q26.0 Congenital stenosis of vena cava	0.001	0.999	0.000
N03.1 Focal and segmental glomerular lesions	0.000	0.999	0.001
O36.5 Maternal care for poor foetal growth	0.000	0.999	0.001
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.001	0.999	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.001	0.999	0.000
Q22.6 Hypoplastic right heart syndrome	0.001	0.999	0.000
Q22.5 Ebstein's anomaly	0.001	0.999	0.000
Q22.4 Congenital tricuspid stenosis	0.001	0.999	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.001	0.999	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.001	0.999	0.000
Q22.0 Pulmonary valve atresia	0.001	0.999	0.000
S40.0 Contusion of shoulder and upper arm	0.001	0.999	0.000
S70-S79 Injuries to the hip and thigh	0.001	0.999	0.000
S72.70 Multiple fractures of femur (closed)	0.001	0.999	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.001	0.999	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.001	0.999	0.000
Q20.6 Isomerism of atrial appendages	0.001	0.999	0.000
Q20.5 Discordant atrioventricular connexion	0.001	0.999	0.000
Q20.4 Double inlet ventricle	0.001	0.999	0.000
Q20.3 Discordant ventriculoarterial connexion	0.001	0.999	0.000
Q20.2 Double outlet left ventricle	0.001	0.999	0.000
Q20.1 Double outlet right ventricle	0.001	0.999	0.000
Q20.0 Common arterial trunk	0.001	0.999	0.000
Z94.4 Liver transplant status	0.001	0.999	0.000
S72.20 Subtrochanteric fracture (closed)	0.001	0.999	0.000
S72.81 Fractures of other parts of femur (open)	0.001	0.999	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.999	0.001
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.999	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.999	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.999	0.000
Q25.2 Atresia of aorta	0.001	0.999	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.001	0.999	0.000
Q51.3 Bicornate uterus	0.001	0.999	0.000
M79.18 Myalgia (Other)	0.001	0.999	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.001	0.999	0.000
E22 Hyperfunction of pituitary gland	0.000	0.999	0.001
K77 Liver disorders in diseases classified elsewhere	0.001	0.999	0.000
S75 Injury of blood vessels at hip and thigh level	0.001	0.999	0.000
S72.91 Fracture of femur, part unspecified (open)	0.001	0.999	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.999	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.999	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.999	0.000
Q23.2 Congenital mitral stenosis	0.001	0.999	0.000
Q21 Congenital malformations of cardiac septa	0.001	0.999	0.000
S75.0 Injury of femoral artery	0.001	0.999	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.999	0.001
Q12.0 Congenital cataract	0.001	0.999	0.000
J46 Status asthmaticus	0.000	0.999	0.001
M25.88 Other specified joint disorders (Other)	0.000	0.999	0.001
S72.40 Fracture of lower end of femur (closed)	0.001	0.999	0.000
E21.0 Primary hyperparathyroidism	0.000	0.999	0.001
K00.6 Disturbances in tooth eruption	0.001	0.999	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.001	0.999	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.001	0.999	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.001	0.999	0.000
Q28.1 Other malformations of precerebral vessels	0.001	0.999	0.000
S79.7 Multiple injuries of hip and thigh	0.001	0.999	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.001	0.999	0.000
S74 Injury of nerves at hip and thigh level	0.001	0.999	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.001	0.999	0.000
Q00-Q07 Congenital malformations of the nervous system	0.001	0.999	0.000
Q25.3 Stenosis of aorta	0.001	0.999	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.999	0.001
S78 Traumatic amputation of hip and thigh	0.001	0.999	0.000
S77 Crushing injury of hip and thigh	0.001	0.999	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.999	0.001
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.999	0.001
S72.80 Fractures of other parts of femur (closed)	0.001	0.999	0.000
M31.8 Other specified necrotising vasculopathies	0.001	0.999	0.000
R47.8 Other and unspecified speech disturbances	0.001	0.999	0.000
Y57.9 Drug or medicament, unspecified	0.001	0.999	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.999	0.001
M31 Other necrotising vasculopathies	0.001	0.999	0.000
Q07 Other congenital malformations of nervous system	0.001	0.999	0.000
E22.8 Other hyperfunction of pituitary gland	0.000	0.999	0.001
E89.3 Postprocedural hypopituitarism	0.001	0.999	0.000
H47.2 Optic atrophy	0.000	0.999	0.001
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
O36.4 Maternal care for intra-uterine death	0.000	0.999	0.001
Q25.1 Coarctation of aorta	0.001	0.999	0.000
Q28.3 Other malformations of cerebral vessels	0.001	0.999	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.999	0.001
S43.4 Sprain and strain of shoulder joint	0.001	0.999	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.001	0.999	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.001	0.999	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.001	0.999	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.001	0.999	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.001	0.999	0.000
X41.9 Unspecified place	0.000	0.999	0.001
S40 Superficial injury of shoulder and upper arm	0.001	0.999	0.000
S92.00 Fracture of calcaneus (closed)	0.001	0.999	0.000
H49.0 Third [oculomotor] nerve palsy	0.001	0.999	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.999	0.001
N97.9 Female infertility, unspecified	0.001	0.999	0.000
Q07.8 Other specified congenital malformations of nervous system	0.001	0.999	0.000
Q21.4 Aortopulmonary septal defect	0.001	0.999	0.000
Q21.3 Tetralogy of Fallot	0.001	0.999	0.000
Q21.2 Atrioventricular septal defect	0.001	0.999	0.000
Q25.0 Patent ductus arteriosus	0.001	0.999	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.001	0.999	0.000
S70.8 Other superficial injuries of hip and thigh	0.001	0.999	0.000
S73.0 Dislocation of hip	0.001	0.999	0.000
H52 Disorders of refraction and accommodation	0.000	0.999	0.001
M43.17 Spondylolisthesis (Lumbosacral region)	0.001	0.999	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.001	0.999	0.000
M31.9 Necrotising vasculopathy, unspecified	0.001	0.999	0.000
M33.1 Other dermatomyositis	0.000	0.999	0.001
S19.9 Unspecified injury of neck	0.000	0.999	0.001
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.001	0.999	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.001	0.999	0.000
S43.2 Dislocation of sternoclavicular joint	0.001	0.999	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.001	0.999	0.000
S74.8 Injury of other nerves at hip and thigh level	0.001	0.999	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.001	0.999	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.001	0.999	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.001	0.999	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.001	0.999	0.000
K70 Alcoholic liver disease	0.000	0.999	0.001
Q06 Other congenital malformations of spinal cord	0.001	0.999	0.000
Q04 Other congenital malformations of brain	0.001	0.999	0.000
Q01 Encephalocele	0.001	0.999	0.000
Q00 Anencephaly and similar malformations	0.001	0.999	0.000
Q02 Microcephaly	0.001	0.999	0.000
M25.82 Other specified joint disorders (Upper arm)	0.000	0.999	0.001
S72.90 Fracture of femur, part unspecified (closed)	0.001	0.999	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.999	0.001
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.999	0.001
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.999	0.001
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.999	0.001
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.999	0.001
G63.1 Polyneuropathy in neoplastic disease	0.000	0.999	0.001
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
J20.8 Acute bronchitis due to other specified organisms	0.000	0.999	0.001
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.999	0.001
K72.0 Acute and subacute hepatic failure	0.001	0.999	0.000
N03.8 Other	0.000	0.999	0.001
Q07.9 Congenital malformation of nervous system, unspecified	0.001	0.999	0.000
Q07.0 Arnold-Chiari syndrome	0.001	0.999	0.000
S77.2 Crushing injury of hip with thigh	0.001	0.999	0.000
S77.1 Crushing injury of thigh	0.001	0.999	0.000
S77.0 Crushing injury of hip	0.001	0.999	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.001	0.999	0.000
S78.1 Traumatic amputation at level between hip and knee	0.001	0.999	0.000
S78.0 Traumatic amputation at hip joint	0.001	0.999	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.999	0.001
H47.7 Disorder of visual pathways, unspecified	0.000	0.999	0.001
H47.6 Disorders of visual cortex	0.000	0.999	0.001
H47.4 Disorders of optic chiasm	0.000	0.999	0.001
H52.4 Presbyopia	0.000	0.999	0.001
M31.7 Microscopic polyangiitis	0.001	0.999	0.000
M31.2 Lethal midline granuloma	0.001	0.999	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.001	0.999	0.000
S70.1 Contusion of thigh	0.001	0.999	0.000
X23.0 Home	0.000	0.999	0.001
X78.0 Home	0.001	0.999	0.000
Y52.1 Calcium-channel blockers	0.001	0.999	0.000
Z95.1 Presence of aortocoronary bypass graft	0.001	0.999	0.000
H52.6 Other disorders of refraction	0.000	0.999	0.001
H52.5 Disorders of accommodation	0.000	0.999	0.001
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.999	0.001
M31.4 Aortic arch syndrome [Takayasu]	0.001	0.999	0.000
Q04.8 Other specified congenital malformations of brain	0.001	0.999	0.000
Q21.8 Other congenital malformations of cardiac septa	0.001	0.999	0.000
S79.9 Unspecified injury of hip and thigh	0.001	0.999	0.000
K71 Toxic liver disease	0.001	0.999	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.999	0.001
H47.5 Disorders of other visual pathways	0.000	0.999	0.001
Q04.9 Congenital malformation of brain, unspecified	0.001	0.999	0.000
Q04.5 Megalencephaly	0.001	0.999	0.000
Q04.4 Septo-optic dysplasia	0.001	0.999	0.000
Q04.3 Other reduction deformities of brain	0.001	0.999	0.000
Q04.2 Holoprosencephaly	0.001	0.999	0.000
Q04.1 Arhinencephaly	0.001	0.999	0.000
Q04.0 Congenital malformations of corpus callosum	0.001	0.999	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.001	0.999	0.000
S73.1 Sprain and strain of hip	0.001	0.999	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.999	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.001	0.999	0.000
Z97.3 Presence of spectacles and contact lenses	0.001	0.999	0.000
N03 Chronic nephritic syndrome	0.000	0.999	0.001
Q03 Congenital hydrocephalus	0.001	0.999	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.001	0.999	0.000
M25.86 Other specified joint disorders (Lower leg)	0.000	0.999	0.001
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.001	0.999	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.999	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.999	0.001
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.001	0.999	0.000
M31.3 Wegener's granulomatosis	0.001	0.999	0.000
O41.0 Oligohydramnios	0.001	0.999	0.000
Q00.2 Iniencephaly	0.001	0.999	0.000
Q00.1 Craniorachischisis	0.001	0.999	0.000
Q00.0 Anencephaly	0.001	0.999	0.000
Q01.9 Encephalocele, unspecified	0.001	0.999	0.000
Q01.8 Encephalocele of other sites	0.001	0.999	0.000
Q01.2 Occipital encephalocele	0.001	0.999	0.000
Q01.1 Nasofrontal encephalocele	0.001	0.999	0.000
Q01.0 Frontal encephalocele	0.001	0.999	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.001	0.999	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.001	0.999	0.000
Q06.4 Hydromyelia	0.001	0.999	0.000
Q06.3 Other congenital cauda equina malformations	0.001	0.999	0.000
Q06.2 Diastematomyelia	0.001	0.999	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.001	0.999	0.000
Q06.0 Amyelia	0.001	0.999	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.001	0.999	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.001	0.999	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.999	0.001
A60.0 Herpesviral infection of genitalia and urogenital tract	0.001	0.999	0.000
M16.3 Other dysplastic coxarthrosis	0.001	0.999	0.000
M31.1 Thrombotic microangiopathy	0.001	0.999	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.001	0.999	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations