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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2253981
log Bayes Factor = 27.196
Chromosome 6   position 29,805,922  (GRCh37) Explore rs2253981 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.003 0.997
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.007 0.993
E70-E90 Metabolic disorders
0.000 0.007 0.993
E83 Disorders of mineral metabolism
0.000 0.008 0.992
E16 Other disorders of pancreatic internal secretion
0.000 0.010 0.990
E16.2 Hypoglycaemia, unspecified
0.000 0.012 0.988
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.020 0.980
E00-E07 Disorders of thyroid gland
0.000 0.021 0.979
E05.9 Thyrotoxicosis, unspecified
0.000 0.025 0.975
E10.9 Without complications
0.000 0.033 0.967
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.035 0.965
E10.1 With ketoacidosis
0.000 0.055 0.945
E10.3 With ophthalmic complications
0.000 0.055 0.945
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.080 0.920
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.082 0.918
E10.4 With neurological complications
0.000 0.122 0.878
E89.0 Postprocedural hypothyroidism
0.000 0.125 0.875
E80.4 Gilbert's syndrome
0.000 0.148 0.852
N40 Hyperplasia of prostate
0.848 0.152 0.000
L40.8 Other psoriasis
0.000 0.175 0.825
E10.6 With other specified complications
0.000 0.186 0.814
E85 Amyloidosis
0.000 0.190 0.810
E10.5 With peripheral circulatory complications
0.000 0.205 0.795
E10.0 With coma
0.000 0.210 0.790
E10.2 With renal complications
0.000 0.240 0.760
L40.3 Pustulosis palmaris et plantaris
0.000 0.258 0.742
E73 Lactose intolerance
0.000 0.258 0.742
E89.2 Postprocedural hypoparathyroidism
0.000 0.259 0.741
E14 Unspecified diabetes mellitus
0.000 0.262 0.738
E79 Disorders of purine and pyrimidine metabolism
0.000 0.279 0.721
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.285 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.286 0.714
E15 Nondiabetic hypoglycaemic coma
0.000 0.288 0.712
E84 Cystic fibrosis
0.000 0.288 0.712
E77 Disorders of glycoprotein metabolism
0.000 0.288 0.712
E76 Disorders of glycosaminoglycan metabolism
0.000 0.288 0.712
E72 Other disorders of amino-acid metabolism
0.000 0.288 0.712
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.288 0.712
E70 Disorders of aromatic amino-acid metabolism
0.000 0.288 0.712
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.288 0.712
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.289 0.711
E83.8 Other disorders of mineral metabolism
0.000 0.289 0.711
E83.2 Disorders of zinc metabolism
0.000 0.289 0.711
E83.0 Disorders of copper metabolism
0.000 0.289 0.711
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.290 0.710
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.290 0.710
E16.4 Abnormal secretion of gastrin
0.000 0.290 0.710
E16.3 Increased secretion of glucagon
0.000 0.290 0.710
E80.2 Other porphyria
0.000 0.292 0.708
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.293 0.707
E16.1 Other hypoglycaemia
0.000 0.295 0.705
E05.5 Thyroid crisis or storm
0.000 0.297 0.703
E05.4 Thyrotoxicosis factitia
0.000 0.297 0.703
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.297 0.703
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.297 0.703
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.298 0.702
E00 Congenital iodine-deficiency syndrome
0.000 0.298 0.702
E11 Non-insulin-dependent diabetes mellitus
0.000 0.299 0.701
E74 Other disorders of carbohydrate metabolism
0.000 0.299 0.701
E05.8 Other thyrotoxicosis
0.000 0.314 0.686
E89.4 Postprocedural ovarian failure
0.000 0.314 0.685
E14.3 With ophthalmic complications
0.000 0.317 0.683
E80.1 Porphyria cutanea tarda
0.000 0.318 0.682
E10.8 With unspecified complications
0.000 0.320 0.680
E11.3 With ophthalmic complications
0.000 0.323 0.677
E85.9 Amyloidosis, unspecified
0.000 0.328 0.672
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.340 0.660
E80.5 Crigler-Najjar syndrome
0.000 0.340 0.660
E80.3 Defects of catalase and peroxydase
0.000 0.340 0.660
E80.0 Hereditary erythropoietic porphyria
0.000 0.340 0.660
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.341 0.658
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.341 0.658
E89.5 Postprocedural testicular hypofunction
0.000 0.341 0.658
E80.6 Other disorders of bilirubin metabolism
0.000 0.343 0.657
E85.4 Organ-limited amyloidosis
0.000 0.346 0.654
L40.4 Guttate psoriasis
0.000 0.346 0.654
E13 Other specified diabetes mellitus
0.000 0.353 0.647
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.357 0.643
L40.0 Psoriasis vulgaris
0.000 0.366 0.634
E40-E46 Malnutrition
0.000 0.385 0.615
E89.3 Postprocedural hypopituitarism
0.000 0.390 0.610
E88 Other metabolic disorders
0.000 0.406 0.594
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.408 0.592
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.419 0.580
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.419 0.580
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.419 0.580
E89.1 Postprocedural hypoinsulinaemia
0.000 0.425 0.574
E11.5 With peripheral circulatory complications
0.000 0.427 0.573
E07 Other disorders of thyroid
0.000 0.429 0.571
E85.3 Secondary systemic amyloidosis
0.000 0.433 0.567
E73.9 Lactose intolerance, unspecified
0.000 0.438 0.562
E50-E64 Other nutritional deficiencies
0.000 0.440 0.560
E14.6 With other specified complications
0.000 0.443 0.557
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.448 0.552
E14.8 With unspecified complications
0.000 0.451 0.549
E14.5 With peripheral circulatory complications
0.000 0.451 0.549
E14.4 With neurological complications
0.000 0.465 0.535
E73.8 Other lactose intolerance
0.000 0.468 0.532
E73.1 Secondary lactase deficiency
0.000 0.468 0.532
E73.0 Congenital lactase deficiency
0.000 0.468 0.532
E11.1 With ketoacidosis
0.000 0.469 0.531
E14.7 With multiple complications
0.000 0.471 0.529
E14.0 With coma
0.000 0.471 0.529
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.474 0.526
E11.8 With unspecified complications
0.000 0.481 0.519
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.483 0.517
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.483 0.517
E79.1 Lesch-Nyhan syndrome
0.000 0.483 0.517
E14.1 With ketoacidosis
0.000 0.484 0.516
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.490 0.510
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.490 0.510
E70.3 Albinism
0.000 0.490 0.510
E70.2 Disorders of tyrosine metabolism
0.000 0.490 0.510
E70.1 Other hyperphenylalaninaemias
0.000 0.490 0.510
E70.0 Classical phenylketonuria
0.000 0.490 0.510
E71.3 Disorders of fatty-acid metabolism
0.000 0.490 0.510
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.490 0.510
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.490 0.510
E71.0 Maple-syrup-urine disease
0.000 0.490 0.510
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.490 0.510
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.490 0.510
E72.5 Disorders of glycine metabolism
0.000 0.490 0.510
E72.4 Disorders of ornithine metabolism
0.000 0.490 0.510
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.490 0.510
E72.2 Disorders of urea cycle metabolism
0.000 0.490 0.510
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.490 0.510
E72.0 Disorders of amino-acid transport
0.000 0.490 0.510
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.490 0.510
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.490 0.510
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.490 0.510
E76.2 Other mucopolysaccharidoses
0.000 0.490 0.510
E76.1 Mucopolysaccharidosis, type II
0.000 0.490 0.510
E76.0 Mucopolysaccharidosis, type I
0.000 0.490 0.510
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.490 0.510
E77.8 Other disorders of glycoprotein metabolism
0.000 0.490 0.510
E77.1 Defects in glycoprotein degradation
0.000 0.490 0.510
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.490 0.510
E84.9 Cystic fibrosis, unspecified
0.000 0.490 0.510
E84.8 Cystic fibrosis with other manifestations
0.000 0.490 0.510
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.490 0.510
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.490 0.510
E85.8 Other amyloidosis
0.000 0.494 0.505
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.496 0.503
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.496 0.503
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.496 0.503
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.496 0.503
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.496 0.503
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.496 0.503
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.496 0.503
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.496 0.503
E11.7 With multiple complications
0.000 0.497 0.503
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.497 0.503
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.497 0.503
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.497 0.503
E74.2 Disorders of galactose metabolism
0.000 0.497 0.503
E74.1 Disorders of fructose metabolism
0.000 0.497 0.503
E74.0 Glycogen storage disease
0.000 0.497 0.503
E03 Other hypothyroidism
0.000 0.498 0.502
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.508 0.492
E65-E68 Obesity and other hyperalimentation
0.000 0.517 0.483
E11.4 With neurological complications
0.000 0.531 0.469
E13.8 With unspecified complications
0.000 0.536 0.464
E13.7 With multiple complications
0.000 0.536 0.464
E13.6 With other specified complications
0.000 0.536 0.464
E13.5 With peripheral circulatory complications
0.000 0.536 0.464
E13.4 With neurological complications
0.000 0.536 0.464
E13.3 With ophthalmic complications
0.000 0.536 0.464
E13.2 With renal complications
0.000 0.536 0.464
E13.1 With ketoacidosis
0.000 0.536 0.464
E13.0 With coma
0.000 0.536 0.464
E83.3 Disorders of phosphorus metabolism
0.000 0.536 0.463
E75.6 Lipid storage disorder, unspecified
0.000 0.539 0.461
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.539 0.461
E75.3 Sphingolipidosis, unspecified
0.000 0.539 0.461
E75.2 Other sphingolipidosis
0.000 0.539 0.461
E75.1 Other gangliosidosis
0.000 0.539 0.461
E75.0 GM2 gangliosidosis
0.000 0.539 0.461
E14.2 Withrenal complications
0.000 0.541 0.459
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.547 0.453
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.559 0.441
E45 Retarded development following protein-energy malnutrition
0.000 0.559 0.441
E43 Unspecified severe protein-energy malnutrition
0.000 0.559 0.441
E42 Marasmic kwashiorkor
0.000 0.559 0.441
E41 Nutritional marasmus
0.000 0.559 0.441
E40 Kwashiorkor
0.000 0.559 0.441
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.568 0.431
K90 Intestinal malabsorption
0.000 0.570 0.430
E58 Dietary calcium deficiency
0.000 0.576 0.424
E07.1 Dyshormogenetic goitre
0.000 0.591 0.409
E07.0 Hypersecretion of calcitonin
0.000 0.591 0.409
E11.0 With coma
0.000 0.592 0.407
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.599 0.401
E63 Other nutritional deficiencies
0.000 0.599 0.401
E56 Other vitamin deficiencies
0.000 0.599 0.401
E50 Vitamin A deficiency
0.000 0.599 0.401
E60 Dietary zinc deficiency
0.000 0.599 0.401
E59 Dietary selenium deficiency
0.000 0.599 0.401
E54 Ascorbic acid deficiency
0.000 0.599 0.401
E52 Niacin deficiency [pellagra]
0.000 0.599 0.401
E51 Thiamine deficiency
0.000 0.600 0.400
E88.8 Other specified metabolic disorders
0.000 0.602 0.398
E13.9 Without complications
0.000 0.604 0.395
E75.5 Other lipid storage disorders
0.000 0.607 0.392
E88.3 Tumour lysis syndrome
0.000 0.608 0.391
E88.9 Metabolic disorder, unspecified
0.000 0.610 0.390
E53 Deficiency of other B group vitamins
0.000 0.610 0.390
E88.2 Lipomatosis, not elsewhere classified
0.000 0.612 0.387
E11.6 With other specified complications
0.000 0.615 0.384
E07.9 Disorder of thyroid, unspecified
0.000 0.620 0.380
E03.8 Other specified hypothyroidism
0.000 0.625 0.374
E03.5 Myxoedema coma
0.000 0.640 0.360
E03.4 Atrophy of thyroid (acquired)
0.000 0.640 0.360
E03.3 Postinfectious hypothyroidism
0.000 0.640 0.360
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.640 0.360
E65 Localised adiposity
0.000 0.645 0.355
E03.1 Congenital hypothyroidism without goitre
0.000 0.648 0.352
E61 Deficiency of other nutrient elements
0.000 0.648 0.352
K90.9 Intestinal malabsorption, unspecified
0.000 0.648 0.352
E11.2 With renal complications
0.000 0.649 0.351
E67 Other hyperalimentation
0.000 0.654 0.346
E68 Sequelae of hyperalimentation
0.000 0.654 0.346
E46 Unspecified protein-energy malnutrition
0.000 0.659 0.341
E07.8 Other specified disorders of thyroid
0.000 0.677 0.323
E44.1 Mild protein-energy malnutrition
0.000 0.683 0.316
E44.0 Moderate protein-energy malnutrition
0.000 0.683 0.316
K90.3 Pancreatic steatorrhoea
0.000 0.691 0.309
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.691 0.309
K90.1 Tropical sprue
0.000 0.691 0.309
K90.8 Other intestinal malabsorption
0.000 0.699 0.301
E55 Vitamin D deficiency
0.000 0.699 0.301
E03.9 Hypothyroidism, unspecified
0.000 0.709 0.291
E50.9 Vitamin A deficiency, unspecified
0.000 0.712 0.288
E50.8 Other manifestations of vitamin A deficiency
0.000 0.712 0.288
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.712 0.288
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.712 0.288
E50.5 Vitamin A deficiency with night blindness
0.000 0.712 0.288
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.712 0.288
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.712 0.288
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.712 0.288
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.712 0.288
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.712 0.288
E56.9 Vitamin deficiency, unspecified
0.000 0.712 0.288
E56.8 Deficiency of other vitamins
0.000 0.712 0.288
E56.1 Deficiency of vitamin K
0.000 0.712 0.288
E56.0 Deficiency of vitamin E
0.000 0.712 0.288
E63.9 Nutritional deficiency, unspecified
0.000 0.712 0.288
E63.8 Other specified nutritional deficiencies
0.000 0.712 0.288
E63.1 Imbalance of constituents of food intake
0.000 0.712 0.288
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.712 0.288
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.712 0.288
E64.8 Sequelae of other nutritional deficiencies
0.000 0.712 0.288
E64.3 Sequelae of rickets
0.000 0.712 0.288
E64.2 Sequelae of vitamin C deficiency
0.000 0.712 0.288
E64.1 Sequelae of vitamin A deficiency
0.000 0.712 0.288
E64.0 Sequelae of protein-energy malnutrition
0.000 0.712 0.288
E51.9 Thiamine deficiency, unspecified
0.000 0.713 0.287
E51.8 Other manifestations of thiamine deficiency
0.000 0.713 0.287
E51.1 Beriberi
0.000 0.713 0.287
E51.2 Wernicke's encephalopathy
0.000 0.714 0.286
E53.8 Deficiency of other specified B group vitamins
0.000 0.715 0.285
E53.1 Pyridoxine deficiency
0.000 0.720 0.280
E53.0 Riboflavin deficiency
0.000 0.720 0.280
E53.9 Vitamin B deficiency, unspecified
0.000 0.738 0.262
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.740 0.259
E61.9 Deficiency of nutrient element, unspecified
0.000 0.747 0.252
E61.8 Deficiency of other specified nutrient elements
0.000 0.747 0.252
E61.7 Deficiency of multiple nutrient elements
0.000 0.747 0.252
E61.6 Vanadium deficiency
0.000 0.747 0.252
E61.5 Molybdenum deficiency
0.000 0.747 0.252
E61.4 Chromium deficiency
0.000 0.747 0.252
E61.3 Manganese deficiency
0.000 0.747 0.252
E61.2 Magnesium deficiency
0.000 0.747 0.252
E61.0 Copper deficiency
0.000 0.747 0.252
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.749 0.251
E04 Other non-toxic goitre
0.000 0.751 0.249
E67.8 Other specified hyperalimentation
0.000 0.751 0.248
E67.3 Hypervitaminosis D
0.000 0.751 0.248
E67.2 Megavitamin-B6 syndrome
0.000 0.751 0.248
E67.1 Hypercarotenaemia
0.000 0.751 0.248
E67.0 Hypervitaminosis A
0.000 0.751 0.248
L40-L45 Papulosquamous disorders
0.000 0.766 0.234
E06 Thyroiditis
0.001 0.767 0.231
E83.4 Disorders of magnesium metabolism
0.000 0.767 0.233
E55.0 Rickets, active
0.000 0.784 0.216
E61.1 Iron deficiency
0.000 0.797 0.203
E04.8 Other specified non-toxic goitre
0.000 0.821 0.179
L44 Other papulosquamous disorders
0.000 0.832 0.168
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.832 0.168
E06.4 Drug-induced thyroiditis
0.001 0.833 0.166
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.001 0.833 0.166
E06.0 Acute thyroiditis
0.001 0.833 0.166
L42 Pityriasis rosea
0.000 0.833 0.167
E04.0 Non-toxic diffuse goitre
0.000 0.833 0.167
E04.1 Non-toxic single thyroid nodule
0.000 0.836 0.164
L41 Parapsoriasis
0.000 0.852 0.148
E06.1 Subacute thyroiditis
0.001 0.854 0.145
E06.5 Other chronic thyroiditis
0.001 0.858 0.141
E83.5 Disorders of calcium metabolism
0.000 0.866 0.134
L44.9 Papulosquamous disorder, unspecified
0.000 0.879 0.120
L44.8 Other specified papulosquamous disorders
0.000 0.879 0.120
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.879 0.120
L44.3 Lichen ruber moniliformis
0.000 0.879 0.120
L44.2 Lichen striatus
0.000 0.879 0.120
L44.1 Lichen nitidus
0.000 0.879 0.120
L44.0 Pityriasis rubra pilaris
0.000 0.879 0.120
E55.9 Vitamin D deficiency, unspecified
0.000 0.885 0.115
E06.9 Thyroiditis, unspecified
0.002 0.890 0.109
L43 Lichen planus
0.000 0.891 0.109
L41.9 Parapsoriasis, unspecified
0.000 0.894 0.106
L41.8 Other parapsoriasis
0.000 0.894 0.106
L41.5 Retiform parapsoriasis
0.000 0.894 0.106
L41.4 Large plaque parapsoriasis
0.000 0.894 0.106
L41.3 Small plaque parapsoriasis
0.000 0.894 0.106
L41.2 Lymphomatoid papulosis
0.000 0.894 0.106
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.894 0.106
E04.9 Non-toxic goitre, unspecified
0.000 0.901 0.099
E66 Obesity
0.000 0.910 0.090
L41.1 Pityriasis lichenoides chronica
0.001 0.914 0.086
L43.3 Subacute (active) lichen planus
0.000 0.921 0.079
L43.2 Lichenoid drug reaction
0.000 0.921 0.079
L43.1 Bullous lichen planus
0.000 0.921 0.079
L43.0 Hypertrophic lichen planus
0.000 0.921 0.079
E06.3 Autoimmune thyroiditis
0.001 0.923 0.076
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.923 0.076
E04.2 Non-toxic multinodular goitre
0.000 0.924 0.076
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.931 0.069
E78.8 Other disorders of lipoprotein metabolism
0.000 0.935 0.065
E66.1 Drug-induced obesity
0.000 0.935 0.065
L43.8 Other lichen planus
0.000 0.938 0.062
E78.6 Lipoprotein deficiency
0.000 0.940 0.060
E20-E35 Disorders of other endocrine glands
0.000 0.941 0.059
E66.0 Obesity due to excess calories
0.000 0.945 0.055
E78.4 Other hyperlipidaemia
0.000 0.949 0.051
L43.9 Lichen planus, unspecified
0.000 0.949 0.051
E78.3 Hyperchylomicronaemia
0.000 0.951 0.049
E34 Other endocrine disorders
0.000 0.952 0.048
E78.1 Pure hyperglyceridaemia
0.000 0.953 0.046
E24 Cushing's syndrome
0.000 0.954 0.046
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.957 0.043
E32 Diseases of thymus
0.000 0.957 0.043
E31 Polyglandular dysfunction
0.000 0.957 0.043
E30 Disorders of puberty, not elsewhere classified
0.000 0.957 0.043
E25 Adrenogenital disorders
0.000 0.958 0.042
E34.9 Endocrine disorder, unspecified
0.000 0.958 0.042
E78.2 Mixed hyperlipidaemia
0.000 0.958 0.041
E20 Hypoparathyroidism
0.000 0.959 0.041
E28 Ovarian dysfunction
0.000 0.962 0.038
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.962 0.038
N40-N51 Diseases of male genital organs
0.035 0.965 0.000
E29 Testicular dysfunction
0.000 0.965 0.035
E24.2 Drug-induced Cushing's syndrome
0.000 0.965 0.035
E34.5 Androgen resistance syndrome
0.000 0.965 0.034
E34.4 Constitutional tall stature
0.000 0.965 0.034
E34.3 Short stature, not elsewhere classified
0.000 0.965 0.034
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.965 0.034
E34.1 Other hypersecretion of intestinal hormones
0.000 0.965 0.034
E24.9 Cushing's syndrome, unspecified
0.000 0.966 0.034
E24.0 Pituitary-dependent Cushing's disease
0.000 0.966 0.033
E26 Hyperaldosteronism
0.000 0.967 0.033
N42.1 Congestion and haemorrhage of prostate
0.033 0.967 0.000
E24.8 Other Cushing's syndrome
0.000 0.967 0.033
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.967 0.033
E24.3 Ectopic ACTH syndrome
0.000 0.967 0.033
E24.1 Nelson's syndrome
0.000 0.967 0.033
E34.8 Other specified endocrine disorders
0.000 0.967 0.033
E28.3 Primary ovarian failure
0.000 0.967 0.033
N42 Other disorders of prostate
0.032 0.968 0.000
E34.0 Carcinoid syndrome
0.000 0.968 0.032
E30.9 Disorder of puberty, unspecified
0.000 0.969 0.031
E30.8 Other disorders of puberty
0.000 0.969 0.031
E30.1 Precocious puberty
0.000 0.969 0.031
E30.0 Delayed puberty
0.000 0.969 0.031
E31.9 Polyglandular dysfunction, unspecified
0.000 0.969 0.031
E31.8 Other polyglandular dysfunction
0.000 0.969 0.031
E31.1 Polyglandular hyperfunction
0.000 0.969 0.031
E31.0 Autoimmune polyglandular failure
0.000 0.969 0.031
E32.9 Disease of thymus, unspecified
0.000 0.969 0.031
E32.8 Other diseases of thymus
0.000 0.969 0.031
E32.1 Abscess of thymus
0.000 0.969 0.031
E32.0 Persistent hyperplasia of thymus
0.000 0.969 0.031
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.969 0.031
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.969 0.031
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.969 0.031
E27 Other disorders of adrenal gland
0.000 0.969 0.031
N41 Inflammatory diseases of prostate
0.031 0.969 0.000
E14.9 Without complications
0.000 0.969 0.031
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.969 0.031
E25.9 Adrenogenital disorder, unspecified
0.000 0.970 0.030
E25.8 Other adrenogenital disorders
0.000 0.970 0.030
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.970 0.030
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.970 0.030
N41.9 Inflammatory disease of prostate, unspecified
0.030 0.970 0.000
E20.8 Other hypoparathyroidism
0.000 0.970 0.029
E20.1 Pseudohypoparathyroidism
0.000 0.970 0.029
E20.0 Idiopathic hypoparathyroidism
0.000 0.970 0.029
E22 Hyperfunction of pituitary gland
0.000 0.971 0.029
E20.9 Hypoparathyroidism, unspecified
0.000 0.972 0.028
E28.9 Ovarian dysfunction, unspecified
0.000 0.972 0.028
E28.8 Other ovarian dysfunction
0.000 0.972 0.028
E28.1 Androgen excess
0.000 0.972 0.028
E28.0 Oestrogen excess
0.000 0.972 0.028
E87.3 Alkalosis
0.000 0.972 0.028
K90-K93 Other diseases of the digestive system
0.000 0.972 0.028
E27.1 Primary adrenocortical insufficiency
0.000 0.974 0.026
N46 Male infertility
0.026 0.974 0.000
L03.1 Cellulitis of other parts of limb
0.000 0.974 0.026
N42.0 Calculus of prostate
0.026 0.974 0.000
N44 Torsion of testis
0.026 0.974 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.026 0.974 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.974 0.025
E29.8 Other testicular dysfunction
0.000 0.974 0.025
E29.0 Testicular hyperfunction
0.000 0.974 0.025
I71 Aortic aneurysm and dissection
0.025 0.975 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.975 0.025
I71.0 Dissection of aorta [any part]
0.025 0.975 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.975 0.025
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.024 0.976 0.000
E26.8 Other hyperaldosteronism
0.000 0.976 0.024
E26.1 Secondary hyperaldosteronism
0.000 0.976 0.024
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.024 0.976 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.976 0.023
N42.3 Dysplasia of prostate
0.023 0.977 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.977 0.023
E27.2 Addisonian crisis
0.000 0.977 0.023
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.022 0.977 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.978 0.022
E27.0 Other adrenocortical overactivity
0.000 0.978 0.022
N41.8 Other inflammatory diseases of prostate
0.022 0.978 0.000
N41.3 Prostatocystitis
0.022 0.978 0.000
N41.2 Abscess of prostate
0.022 0.978 0.000
N42.8 Other specified disorders of prostate
0.022 0.978 0.000
E87.4 Mixed disorder of acid-base balance
0.000 0.978 0.022
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.979 0.021
E26.9 Hyperaldosteronism, unspecified
0.000 0.979 0.021
N45 Orchitis and epididymitis
0.021 0.979 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.021 0.979 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.979 0.021
E22.8 Other hyperfunction of pituitary gland
0.000 0.979 0.021
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.979 0.021
M06 Other rheumatoid arthritis
0.000 0.979 0.021
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.980 0.020
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.020 0.980 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.980 0.020
N42.2 Atrophy of prostate
0.020 0.980 0.000
N41.0 Acute prostatitis
0.020 0.980 0.000
N51.2 Balanitis in diseases classified elsewhere
0.019 0.981 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.019 0.981 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.981 0.019
E66.8 Other obesity
0.000 0.981 0.019
E26.0 Primary hyperaldosteronism
0.000 0.981 0.019
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.019 0.981 0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.019 0.981 0.000
N51.0 Disorders of prostate in diseases classified elsewhere
0.019 0.981 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.981 0.019
I71.8 Aortic aneurysm of unspecified site, ruptured
0.018 0.982 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.018 0.982 0.000
E29.1 Testicular hypofunction
0.000 0.982 0.018
M07.3 Other psoriatic arthropathies
0.000 0.982 0.018
N41.1 Chronic prostatitis
0.018 0.982 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.982 0.017
M06.3 Rheumatoid nodule
0.000 0.982 0.018
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.983 0.017
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.983 0.017
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.017 0.983 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.983 0.017
M06.4 Inflammatory polyarthropathy
0.000 0.983 0.017
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.017 0.983 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.983 0.016
N49.9 Inflammatory disorder of unspecified male genital organ
0.016 0.984 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.016 0.984 0.000
R60.9 Oedema, unspecified
0.000 0.984 0.016
E87.0 Hyperosmolality and hypernatraemia
0.000 0.984 0.016
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.984 0.016
M06.0 Seronegative rheumatoid arthritis
0.000 0.984 0.016
M06.8 Other specified rheumatoid arthritis
0.000 0.985 0.015
M06.2 Rheumatoid bursitis
0.000 0.985 0.015
M06.1 Adult-onset Still's disease
0.000 0.985 0.015
M07 Psoriatic and enteropathic arthropathies
0.000 0.985 0.015
L28.0 Lichen simplex chronicus
0.000 0.985 0.015
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.985 0.015

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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