TreeWAS – Variant ID: rs2261181

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	0.999	0.001	0.000
E10-E14 Diabetes mellitus	0.970	0.030	0.000
E14 Unspecified diabetes mellitus	0.954	0.046	0.000
E14.9 Without complications	0.939	0.061	0.000
E11.3 With ophthalmic complications	0.929	0.071	0.000
E11.2 With renal complications	0.918	0.082	0.000
E10 Insulin-dependent diabetes mellitus	0.899	0.101	0.000
E10.9 Without complications	0.857	0.143	0.000
E11.5 With peripheral circulatory complications	0.857	0.143	0.000
E11.6 With other specified complications	0.852	0.148	0.000
E11.8 With unspecified complications	0.807	0.193	0.000
E11.1 With ketoacidosis	0.783	0.217	0.000
E10.4 With neurological complications	0.768	0.232	0.000
E10.8 With unspecified complications	0.752	0.248	0.000
E14.5 With peripheral circulatory complications	0.744	0.256	0.000
E11.7 With multiple complications	0.716	0.283	0.000
E14.3 With ophthalmic complications	0.698	0.302	0.000
E12 Malnutrition-related diabetes mellitus	0.695	0.305	0.000
E14.8 With unspecified complications	0.684	0.316	0.000
E14.7 With multiple complications	0.684	0.316	0.000
E14.6 With other specified complications	0.684	0.316	0.000
E14.4 With neurological complications	0.684	0.316	0.000
E14.2 Withrenal complications	0.684	0.316	0.000
E14.1 With ketoacidosis	0.684	0.316	0.000
E14.0 With coma	0.684	0.316	0.000
E11.0 With coma	0.666	0.334	0.000
E10.1 With ketoacidosis	0.652	0.348	0.000
E10.2 With renal complications	0.651	0.349	0.000
E10.7 With multiple complications	0.644	0.356	0.000
E11.4 With neurological complications	0.629	0.370	0.000
E10.0 With coma	0.627	0.373	0.000
E10.6 With other specified complications	0.617	0.383	0.000
E13 Other specified diabetes mellitus	0.551	0.449	0.000
E12.9 Without complications	0.498	0.501	0.000
E12.8 With unspecified complications	0.498	0.501	0.000
E12.7 With multiple complications	0.498	0.501	0.000
E12.6 With other specified complications	0.498	0.501	0.000
E12.5 With peripheral circulatory complications	0.498	0.501	0.000
E12.4 With neurological complications	0.498	0.501	0.000
E12.3 With ophthalmic complications	0.498	0.501	0.000
E12.2 With renal complications	0.498	0.501	0.000
E12.1 With ketoacidosis	0.498	0.501	0.000
E12.0 With coma	0.498	0.501	0.000
E10.5 With peripheral circulatory complications	0.412	0.587	0.001
E10.3 With ophthalmic complications	0.400	0.600	0.000
E13.8 With unspecified complications	0.395	0.605	0.000
E13.7 With multiple complications	0.395	0.605	0.000
E13.6 With other specified complications	0.395	0.605	0.000
E13.5 With peripheral circulatory complications	0.395	0.605	0.000
E13.4 With neurological complications	0.395	0.605	0.000
E13.3 With ophthalmic complications	0.395	0.605	0.000
E13.2 With renal complications	0.395	0.605	0.000
E13.1 With ketoacidosis	0.395	0.605	0.000
E13.0 With coma	0.395	0.605	0.000
E13.9 Without complications	0.250	0.749	0.001
M17.1 Other primary gonarthrosis	0.000	0.759	0.241
Chapter IV Endocrine, nutritional and metabolic diseases	0.055	0.945	0.000
E20-E35 Disorders of other endocrine glands	0.046	0.954	0.000
E23 Hypofunction and other disorders of pituitary gland	0.045	0.955	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.043	0.957	0.000
E28 Ovarian dysfunction	0.040	0.960	0.000
E23.2 Diabetes insipidus	0.040	0.960	0.000
E23.0 Hypopituitarism	0.039	0.961	0.000
E50-E64 Other nutritional deficiencies	0.037	0.963	0.000
E40-E46 Malnutrition	0.036	0.964	0.000
E28.2 Polycystic ovarian syndrome	0.036	0.964	0.000
E23.7 Disorder of pituitary gland, unspecified	0.036	0.964	0.000
E34 Other endocrine disorders	0.034	0.966	0.000
E16 Other disorders of pancreatic internal secretion	0.034	0.966	0.000
E26 Hyperaldosteronism	0.034	0.966	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.033	0.967	0.000
E32 Diseases of thymus	0.033	0.967	0.000
E31 Polyglandular dysfunction	0.033	0.967	0.000
E30 Disorders of puberty, not elsewhere classified	0.033	0.967	0.000
E25 Adrenogenital disorders	0.033	0.967	0.000
E20 Hypoparathyroidism	0.033	0.967	0.000
E29 Testicular dysfunction	0.033	0.967	0.000
E61 Deficiency of other nutrient elements	0.033	0.967	0.000
M17 Gonarthrosis [arthrosis of knee]	0.000	0.967	0.033
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.032	0.968	0.000
E23.1 Drug-induced hypopituitarism	0.032	0.968	0.000
E27 Other disorders of adrenal gland	0.032	0.968	0.000
E23.6 Other disorders of pituitary gland	0.032	0.968	0.000
E24 Cushing's syndrome	0.031	0.969	0.000
E15 Nondiabetic hypoglycaemic coma	0.031	0.969	0.000
E28.3 Primary ovarian failure	0.030	0.970	0.000
E28.9 Ovarian dysfunction, unspecified	0.029	0.971	0.000
E28.8 Other ovarian dysfunction	0.029	0.971	0.000
E28.1 Androgen excess	0.029	0.971	0.000
E28.0 Oestrogen excess	0.029	0.971	0.000
E61.1 Iron deficiency	0.029	0.971	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.027	0.973	0.000
Z36.8 Other antenatal screening	0.000	0.973	0.027
E64 Sequelae of malnutrition and other nutritional deficiencies	0.027	0.973	0.000
E63 Other nutritional deficiencies	0.027	0.973	0.000
E56 Other vitamin deficiencies	0.027	0.973	0.000
E51 Thiamine deficiency	0.027	0.973	0.000
E50 Vitamin A deficiency	0.027	0.973	0.000
E60 Dietary zinc deficiency	0.027	0.973	0.000
E59 Dietary selenium deficiency	0.027	0.973	0.000
E58 Dietary calcium deficiency	0.027	0.973	0.000
E54 Ascorbic acid deficiency	0.027	0.973	0.000
E52 Niacin deficiency [pellagra]	0.027	0.973	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.973	0.027
E44 Protein-energy malnutrition of moderate and mild degree	0.026	0.974	0.000
E45 Retarded development following protein-energy malnutrition	0.026	0.974	0.000
E43 Unspecified severe protein-energy malnutrition	0.026	0.974	0.000
E42 Marasmic kwashiorkor	0.026	0.974	0.000
E41 Nutritional marasmus	0.026	0.974	0.000
E40 Kwashiorkor	0.026	0.974	0.000
Z36 Antenatal screening	0.000	0.974	0.026
E16.1 Other hypoglycaemia	0.026	0.974	0.000
E65-E68 Obesity and other hyperalimentation	0.026	0.974	0.000
E34.9 Endocrine disorder, unspecified	0.025	0.974	0.000
M17.3 Other posttraumatic gonarthrosis	0.000	0.975	0.025
E34.0 Carcinoid syndrome	0.025	0.975	0.000
E16.2 Hypoglycaemia, unspecified	0.025	0.975	0.000
E26.0 Primary hyperaldosteronism	0.025	0.975	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.025	0.975	0.000
E34.8 Other specified endocrine disorders	0.025	0.975	0.000
E34.5 Androgen resistance syndrome	0.025	0.975	0.000
E34.4 Constitutional tall stature	0.025	0.975	0.000
E34.3 Short stature, not elsewhere classified	0.025	0.975	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.025	0.975	0.000
E34.1 Other hypersecretion of intestinal hormones	0.025	0.975	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.025	0.975	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.025	0.975	0.000
E16.4 Abnormal secretion of gastrin	0.025	0.975	0.000
E16.3 Increased secretion of glucagon	0.025	0.975	0.000
E26.9 Hyperaldosteronism, unspecified	0.024	0.975	0.000
E26.8 Other hyperaldosteronism	0.024	0.975	0.000
E26.1 Secondary hyperaldosteronism	0.024	0.975	0.000
E20.9 Hypoparathyroidism, unspecified	0.024	0.976	0.000
E20.8 Other hypoparathyroidism	0.024	0.976	0.000
E20.1 Pseudohypoparathyroidism	0.024	0.976	0.000
E20.0 Idiopathic hypoparathyroidism	0.024	0.976	0.000
E25.9 Adrenogenital disorder, unspecified	0.024	0.976	0.000
E25.8 Other adrenogenital disorders	0.024	0.976	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.024	0.976	0.000
E30.9 Disorder of puberty, unspecified	0.024	0.976	0.000
E30.8 Other disorders of puberty	0.024	0.976	0.000
E30.1 Precocious puberty	0.024	0.976	0.000
E30.0 Delayed puberty	0.024	0.976	0.000
E31.9 Polyglandular dysfunction, unspecified	0.024	0.976	0.000
E31.8 Other polyglandular dysfunction	0.024	0.976	0.000
E31.1 Polyglandular hyperfunction	0.024	0.976	0.000
E31.0 Autoimmune polyglandular failure	0.024	0.976	0.000
E32.9 Disease of thymus, unspecified	0.024	0.976	0.000
E32.8 Other diseases of thymus	0.024	0.976	0.000
E32.1 Abscess of thymus	0.024	0.976	0.000
E32.0 Persistent hyperplasia of thymus	0.024	0.976	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.024	0.976	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.024	0.976	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.024	0.976	0.000
E27.2 Addisonian crisis	0.024	0.976	0.000
E29.9 Testicular dysfunction, unspecified	0.023	0.976	0.000
E29.8 Other testicular dysfunction	0.023	0.976	0.000
E29.0 Testicular hyperfunction	0.023	0.976	0.000
E61.9 Deficiency of nutrient element, unspecified	0.023	0.976	0.000
E61.8 Deficiency of other specified nutrient elements	0.023	0.976	0.000
E61.7 Deficiency of multiple nutrient elements	0.023	0.976	0.000
E61.6 Vanadium deficiency	0.023	0.976	0.000
E61.5 Molybdenum deficiency	0.023	0.976	0.000
E61.4 Chromium deficiency	0.023	0.976	0.000
E61.3 Manganese deficiency	0.023	0.976	0.000
E61.2 Magnesium deficiency	0.023	0.976	0.000
E61.0 Copper deficiency	0.023	0.976	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.976	0.024
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.976	0.024
E27.8 Other specified disorders of adrenal gland	0.023	0.977	0.000
E46 Unspecified protein-energy malnutrition	0.023	0.977	0.000
E55 Vitamin D deficiency	0.023	0.977	0.000
E27.5 Adrenomedullary hyperfunction	0.023	0.977	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.023	0.977	0.000
E27.0 Other adrenocortical overactivity	0.023	0.977	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.977	0.023
E29.1 Testicular hypofunction	0.023	0.977	0.000
M17.5 Other secondary gonarthrosis	0.000	0.977	0.023
E24.8 Other Cushing's syndrome	0.022	0.977	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.022	0.977	0.000
E24.3 Ectopic ACTH syndrome	0.022	0.977	0.000
E24.2 Drug-induced Cushing's syndrome	0.022	0.977	0.000
E24.1 Nelson's syndrome	0.022	0.977	0.000
E24.0 Pituitary-dependent Cushing's disease	0.022	0.977	0.000
E22 Hyperfunction of pituitary gland	0.022	0.978	0.000
E27.9 Disorder of adrenal gland, unspecified	0.022	0.978	0.000
E27.1 Primary adrenocortical insufficiency	0.020	0.980	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.980	0.020
E24.9 Cushing's syndrome, unspecified	0.020	0.980	0.000
E50.9 Vitamin A deficiency, unspecified	0.019	0.980	0.000
E50.8 Other manifestations of vitamin A deficiency	0.019	0.980	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.019	0.980	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.019	0.980	0.000
E50.5 Vitamin A deficiency with night blindness	0.019	0.980	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.019	0.980	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.019	0.980	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.019	0.980	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.019	0.980	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.019	0.980	0.000
E51.9 Thiamine deficiency, unspecified	0.019	0.980	0.000
E51.8 Other manifestations of thiamine deficiency	0.019	0.980	0.000
E51.2 Wernicke's encephalopathy	0.019	0.980	0.000
E51.1 Beriberi	0.019	0.980	0.000
E56.9 Vitamin deficiency, unspecified	0.019	0.980	0.000
E56.8 Deficiency of other vitamins	0.019	0.980	0.000
E56.1 Deficiency of vitamin K	0.019	0.980	0.000
E56.0 Deficiency of vitamin E	0.019	0.980	0.000
E63.9 Nutritional deficiency, unspecified	0.019	0.980	0.000
E63.8 Other specified nutritional deficiencies	0.019	0.980	0.000
E63.1 Imbalance of constituents of food intake	0.019	0.980	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.019	0.980	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.019	0.980	0.000
E64.8 Sequelae of other nutritional deficiencies	0.019	0.980	0.000
E64.3 Sequelae of rickets	0.019	0.980	0.000
E64.2 Sequelae of vitamin C deficiency	0.019	0.980	0.000
E64.1 Sequelae of vitamin A deficiency	0.019	0.980	0.000
E64.0 Sequelae of protein-energy malnutrition	0.019	0.980	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.980	0.020
E44.1 Mild protein-energy malnutrition	0.019	0.981	0.000
E44.0 Moderate protein-energy malnutrition	0.019	0.981	0.000
Z36.5 Antenatal screening for isoimmunisation	0.000	0.981	0.019
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.981	0.019
E53 Deficiency of other B group vitamins	0.019	0.981	0.000
E67 Other hyperalimentation	0.019	0.981	0.000
E68 Sequelae of hyperalimentation	0.019	0.981	0.000
E65 Localised adiposity	0.019	0.981	0.000
M17.0 Primary gonarthrosis, bilateral	0.000	0.982	0.018
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.982	0.017
K70.3 Alcoholic cirrhosis of liver	0.000	0.983	0.017
E55.0 Rickets, active	0.017	0.983	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.983	0.017
K70 Alcoholic liver disease	0.000	0.983	0.017
E22.9 Hyperfunction of pituitary gland, unspecified	0.016	0.984	0.000
E22.8 Other hyperfunction of pituitary gland	0.016	0.984	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.015	0.985	0.000
K70.4 Alcoholic hepatic failure	0.000	0.986	0.014
E22.0 Acromegaly and pituitary gigantism	0.014	0.986	0.000
K70.0 Alcoholic fatty liver	0.000	0.986	0.014
K70.1 Alcoholic hepatitis	0.000	0.986	0.014
E53.9 Vitamin B deficiency, unspecified	0.014	0.986	0.000
E53.1 Pyridoxine deficiency	0.014	0.986	0.000
E53.0 Riboflavin deficiency	0.014	0.986	0.000
E22.1 Hyperprolactinaemia	0.013	0.986	0.000
K70-K77 Diseases of liver	0.000	0.986	0.014
E67.8 Other specified hyperalimentation	0.013	0.986	0.000
E67.3 Hypervitaminosis D	0.013	0.986	0.000
E67.2 Megavitamin-B6 syndrome	0.013	0.986	0.000
E67.1 Hypercarotenaemia	0.013	0.986	0.000
E67.0 Hypervitaminosis A	0.013	0.986	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.986	0.014
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.013	0.987	0.000
E55.9 Vitamin D deficiency, unspecified	0.013	0.987	0.000
K75 Other inflammatory liver diseases	0.000	0.987	0.013
K75.0 Abscess of liver	0.000	0.987	0.013
K72 Hepatic failure, not elsewhere classified	0.000	0.988	0.012
K72.9 Hepatic failure, unspecified	0.000	0.988	0.012
E21.5 Disorder of parathyroid gland, unspecified	0.011	0.989	0.000
E21.4 Other specified disorders of parathyroid gland	0.011	0.989	0.000
E21.2 Other hyperparathyroidism	0.011	0.989	0.000
K76 Other diseases of liver	0.000	0.989	0.011
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.989	0.011
K76.9 Liver disease, unspecified	0.000	0.989	0.011
K73 Chronic hepatitis, not elsewhere classified	0.000	0.989	0.010
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.010	0.989	0.000
K75.4 Autoimmune hepatitis	0.000	0.990	0.010
K75.9 Inflammatory liver disease, unspecified	0.000	0.990	0.010
K77 Liver disorders in diseases classified elsewhere	0.000	0.990	0.010
K71 Toxic liver disease	0.000	0.990	0.010
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.990	0.010
K75.2 Nonspecific reactive hepatitis	0.000	0.990	0.010
K75.1 Phlebitis of portal vein	0.000	0.990	0.010
K76.6 Portal hypertension	0.000	0.990	0.010
K72.1 Chronic hepatic failure	0.000	0.991	0.009
K72.0 Acute and subacute hepatic failure	0.000	0.991	0.008
K75.8 Other specified inflammatory liver diseases	0.000	0.992	0.008
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.992	0.008
C50.4 Upper-outer quadrant of breast	0.008	0.992	0.000
L03.0 Cellulitis of finger and toe	0.008	0.992	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.992	0.008
K76.4 Peliosis hepatis	0.000	0.992	0.008
K76.3 Infarction of liver	0.000	0.992	0.008
K76.2 Central haemorrhagic necrosis of liver	0.000	0.992	0.008
K76.1 Chronic passive congestion of liver	0.000	0.992	0.008
K73.9 Chronic hepatitis, unspecified	0.000	0.992	0.008
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.992	0.008
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.992	0.008
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.992	0.008
E21.0 Primary hyperparathyroidism	0.007	0.992	0.000
K76.7 Hepatorenal syndrome	0.000	0.992	0.007
K71.9 Toxic liver disease, unspecified	0.000	0.992	0.007
K71.8 Toxic liver disease with other disorders of liver	0.000	0.992	0.007
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.992	0.007
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.992	0.007
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.992	0.007
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.992	0.007
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.992	0.007
K71.2 Toxic liver disease with acute hepatitis	0.000	0.992	0.007
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.992	0.007
K71.0 Toxic liver disease with cholestasis	0.000	0.992	0.007
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.992	0.007
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.992	0.007
K74 Fibrosis and cirrhosis of liver	0.000	0.993	0.007
M06.9 Rheumatoid arthritis, unspecified	0.000	0.993	0.007
Z89.6 Acquired absence of leg above knee	0.007	0.993	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.993	0.007
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.994	0.006
K74.5 Biliary cirrhosis, unspecified	0.000	0.994	0.006
Z89 Acquired absence of limb	0.006	0.994	0.000
Z89.5 Acquired absence of leg at or below knee	0.006	0.994	0.000
K74.3 Primary biliary cirrhosis	0.000	0.994	0.006
K74.4 Secondary biliary cirrhosis	0.000	0.994	0.005
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.994	0.005
K74.1 Hepatic sclerosis	0.000	0.994	0.005
K76.8 Other specified diseases of liver	0.000	0.994	0.005
E53.8 Deficiency of other specified B group vitamins	0.005	0.995	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.995	0.005
Z89.4 Acquired absence of foot and ankle	0.005	0.995	0.000
E21.3 Hyperparathyroidism, unspecified	0.005	0.995	0.001
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.995	0.005
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.995	0.005
K74.0 Hepatic fibrosis	0.000	0.995	0.005
E66 Obesity	0.005	0.995	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.995	0.005
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.005	0.995	0.000
Y95 Nosocomial condition	0.005	0.995	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.004	0.996	0.000
Z89.9 Acquired absence of limb, unspecified	0.004	0.996	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.004	0.996	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.004	0.996	0.000
Z89.2 Acquired absence of upper limb above wrist	0.004	0.996	0.000
Z89.1 Acquired absence of hand and wrist	0.004	0.996	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.004	0.996	0.000
E00-E07 Disorders of thyroid gland	0.004	0.996	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.996	0.004
E66.0 Obesity due to excess calories	0.004	0.996	0.000
H53.1 Subjective visual disturbances	0.004	0.996	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.004	0.996	0.000
E66.1 Drug-induced obesity	0.004	0.996	0.000
I51.8 Other ill-defined heart diseases	0.000	0.996	0.004
N20.2 Calculus of kidney with calculus of ureter	0.000	0.997	0.003
M06 Other rheumatoid arthritis	0.000	0.997	0.003
R07.2 Precordial pain	0.003	0.997	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.003	0.997	0.000
R42 Dizziness and giddiness	0.003	0.997	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.003	0.997	0.000
E00 Congenital iodine-deficiency syndrome	0.003	0.997	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.003	0.997	0.000
N20 Calculus of kidney and ureter	0.000	0.997	0.003
N20.0 Calculus of kidney	0.000	0.997	0.003
Z88.1 Personal history of allergy to other antibiotic agents	0.003	0.997	0.000
R73.0 Abnormal glucose tolerance test	0.003	0.997	0.000
Z03.8 Observation for other suspected diseases and conditions	0.000	0.997	0.003
H25.8 Other senile cataract	0.003	0.997	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.000	0.997	0.003
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.003	0.997	0.000
M65.34 Trigger finger-Hand	0.003	0.997	0.000
H53.8 Other visual disturbances	0.003	0.997	0.000
N20.1 Calculus of ureter	0.000	0.997	0.003
S09.9 Unspecified injury of head	0.003	0.997	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.997	0.003
N21.0 Calculus in bladder	0.000	0.997	0.003
Z32.0 Pregnancy, not (yet) confirmed	0.000	0.997	0.003
M06.3 Rheumatoid nodule	0.000	0.997	0.003
K82.8 Other specified diseases of gallbladder	0.000	0.997	0.003
M06.8 Other specified rheumatoid arthritis	0.000	0.997	0.003
M06.4 Inflammatory polyarthropathy	0.000	0.997	0.003
M06.2 Rheumatoid bursitis	0.000	0.997	0.003
M06.1 Adult-onset Still's disease	0.000	0.997	0.003
M06.0 Seronegative rheumatoid arthritis	0.000	0.997	0.003
N20.9 Urinary calculus, unspecified	0.000	0.997	0.003
Z32 Pregnancy examination and test	0.000	0.997	0.003
H43.8 Other disorders of vitreous body	0.003	0.997	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.997	0.003
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.000	0.997	0.003
M06.34 Rheumatoid nodule (Hand)	0.000	0.997	0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.997	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.997	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.997	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.997	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.997	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.997	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.997	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.997	0.000
E07 Other disorders of thyroid	0.002	0.997	0.001
E06 Thyroiditis	0.002	0.997	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.997	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.002	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.002	0.998	0.000
Y98 Lifestyle-related condition	0.002	0.998	0.000
Y97 Environmental-pollution-related condition	0.002	0.998	0.000
Y96 Work-related condition	0.002	0.998	0.000
N95.0 Postmenopausal bleeding	0.002	0.998	0.000
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
H53 Visual disturbances	0.002	0.998	0.000
C50.2 Upper-inner quadrant of breast	0.002	0.998	0.000
Z39.0 Care and examination immediately after delivery	0.000	0.998	0.002
S12 Fracture of neck	0.002	0.998	0.000
J38.0 Paralysis of vocal cords and larynx	0.000	0.998	0.002
Z32.1 Pregnancy confirmed	0.000	0.998	0.002
D03.5 Melanoma in situ of trunk	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
I67.2 Cerebral atherosclerosis	0.002	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.002	0.998	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.998	0.002
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.998	0.002
M06.38 Rheumatoid nodule (Other)	0.000	0.998	0.002
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.998	0.002
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.998	0.002
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.998	0.002
M06.33 Rheumatoid nodule (Forearm)	0.000	0.998	0.002
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.998	0.002
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.998	0.002
K62.6 Ulcer of anus and rectum	0.000	0.998	0.002
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.002	0.998	0.000
Y45.1 Salicylates	0.002	0.998	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.002	0.998	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.998	0.002
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.998	0.002
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.998	0.002
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.998	0.002
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.998	0.002
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.998	0.002
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.998	0.002
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.998	0.002
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.998	0.002
M06.18 Adult-onset Still's disease (Other)	0.000	0.998	0.002
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.998	0.002
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.998	0.002
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.998	0.002
M06.14 Adult-onset Still's disease (Hand)	0.000	0.998	0.002
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.998	0.002
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.998	0.002
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.998	0.002
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.998	0.002
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.998	0.002
M06.28 Rheumatoid bursitis (Other)	0.000	0.998	0.002
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.998	0.002
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.998	0.002
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.998	0.002
M06.24 Rheumatoid bursitis (Hand)	0.000	0.998	0.002
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.998	0.002
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.998	0.002
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.998	0.002
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.998	0.002
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.998	0.002
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.998	0.002
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.998	0.002
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.998	0.002
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.998	0.002
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.998	0.002
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.998	0.002
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.998	0.002
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.998	0.002
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.998	0.002
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.998	0.002
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.998	0.002
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.998	0.002
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.998	0.002
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.998	0.002
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.998	0.002
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
M25.84 Other specified joint disorders (Hand)	0.000	0.998	0.002
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.000	0.998	0.002
Z32.9 Pregnancy confirmed (erroneous code. See Z321)	0.000	0.998	0.002
Z39 Postpartum care and examination	0.000	0.998	0.002
Z33 Pregnant state, incidental	0.000	0.998	0.002
X60-X84 Intentional self-harm	0.002	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.998	0.002
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.998	0.002
I47.1 Supraventricular tachycardia	0.000	0.998	0.002
N50.8 Other specified disorders of male genital organs	0.000	0.998	0.002
X78 Intentional self-harm by sharp object	0.002	0.998	0.000
Z35 Supervision of high-risk pregnancy	0.000	0.998	0.002
X78.0 Home	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
E07.1 Dyshormogenetic goitre	0.002	0.998	0.001
E07.0 Hypersecretion of calcitonin	0.002	0.998	0.001
H53.4 Visual field defects	0.002	0.998	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.002	0.998	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.002	0.998	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.002	0.998	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.002	0.998	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.002	0.998	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.002	0.998	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.002	0.998	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.002	0.998	0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations