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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2280406
log Bayes Factor = 5.26177
Chromosome 3   position 49,941,436  (GRCh37) Explore rs2280406 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.006 0.994
E11.4 With neurological complications
0.000 0.014 0.986
E14 Unspecified diabetes mellitus
0.000 0.016 0.984
E14.9 Without complications
0.000 0.037 0.963
E11.2 With renal complications
0.000 0.059 0.941
E10 Insulin-dependent diabetes mellitus
0.000 0.066 0.934
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.000 0.086 0.914
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.000 0.098 0.902
E10.4 With neurological complications
0.000 0.145 0.855
G55.2 Nerve root and plexus compressions in spondylosis
0.000 0.146 0.854
E11.1 With ketoacidosis
0.000 0.152 0.848
E14.4 With neurological complications
0.000 0.166 0.834
G50-G59 Nerve, nerve root and plexus disorders
0.000 0.172 0.828
G56 Mononeuropathies of upper limb
0.000 0.178 0.822
G56.0 Carpal tunnel syndrome
0.000 0.183 0.817
E10.5 With peripheral circulatory complications
0.000 0.190 0.810
E14.2 Withrenal complications
0.000 0.218 0.782
E10.6 With other specified complications
0.000 0.219 0.781
E11.6 With other specified complications
0.000 0.222 0.778
E14.1 With ketoacidosis
0.000 0.224 0.776
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.000 0.226 0.774
G59 Mononeuropathy in diseases classified elsewhere
0.000 0.233 0.767
E14.8 With unspecified complications
0.000 0.248 0.752
E14.3 With ophthalmic complications
0.000 0.256 0.744
G56.3 Lesion of radial nerve
0.000 0.259 0.741
G56.8 Other mononeuropathies of upper limb
0.000 0.265 0.735
E11.8 With unspecified complications
0.000 0.267 0.733
E10.7 With multiple complications
0.000 0.274 0.726
E10.2 With renal complications
0.000 0.276 0.724
G59.0 Diabetic mononeuropathy
0.000 0.277 0.723
G55.0 Nerve root and plexus compressions in neoplastic disease
0.000 0.281 0.719
E11.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.287 0.712
E66.9 Obesity, unspecified
0.000 0.291 0.709
E14.7 With multiple complications
0.000 0.294 0.706
E66 Obesity
0.000 0.298 0.702
E14.6 With other specified complications
0.000 0.302 0.698
E14.0 With coma
0.000 0.309 0.691
E11.5 With peripheral circulatory complications
0.000 0.317 0.683
E10.0 With coma
0.000 0.319 0.681
E65-E68 Obesity and other hyperalimentation
0.000 0.330 0.670
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.359 0.641
G51 Facial nerve disorders
0.000 0.374 0.626
E10.3 With ophthalmic complications
0.000 0.376 0.624
E66.0 Obesity due to excess calories
0.000 0.382 0.618
E66.8 Other obesity
0.000 0.394 0.606
E10.8 With unspecified complications
0.000 0.402 0.598
E11.0 With coma
0.000 0.407 0.593
E14.5 With peripheral circulatory complications
0.000 0.414 0.585
G50 Disorders of trigeminal nerve
0.000 0.436 0.564
G59.8 Other mononeuropathies in diseases classified elsewhere
0.000 0.450 0.550
G51.3 Clonic hemifacial spasm
0.000 0.458 0.542
E10.9 Without complications
0.000 0.461 0.539
E10.1 With ketoacidosis
0.000 0.463 0.537
G53 Cranial nerve disorders in diseases classified elsewhere
0.000 0.469 0.531
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.471 0.529
E13 Other specified diabetes mellitus
0.000 0.475 0.525
G58 Other mononeuropathies
0.000 0.477 0.523
E65 Localised adiposity
0.000 0.481 0.519
E12.9 Without complications
0.000 0.489 0.511
E12.8 With unspecified complications
0.000 0.489 0.511
E12.7 With multiple complications
0.000 0.489 0.511
E12.6 With other specified complications
0.000 0.489 0.511
E12.5 With peripheral circulatory complications
0.000 0.489 0.511
E12.4 With neurological complications
0.000 0.489 0.511
E12.3 With ophthalmic complications
0.000 0.489 0.511
E12.2 With renal complications
0.000 0.489 0.511
E12.1 With ketoacidosis
0.000 0.489 0.511
E12.0 With coma
0.000 0.489 0.511
G56.2 Lesion of ulnar nerve
0.000 0.491 0.509
G52 Disorders of other cranial nerves
0.000 0.495 0.505
E66.1 Drug-induced obesity
0.000 0.496 0.504
E67 Other hyperalimentation
0.000 0.519 0.480
E68 Sequelae of hyperalimentation
0.000 0.519 0.480
G55.3 Nerve root and plexus compressions in other dorsopathies
0.000 0.527 0.473
G56.1 Other lesions of median nerve
0.000 0.533 0.467
G51.8 Other disorders of facial nerve
0.000 0.535 0.465
G50.9 Disorder of trigeminal nerve, unspecified
0.000 0.539 0.461
G50.8 Other disorders of trigeminal nerve
0.000 0.550 0.450
G51.4 Facial myokymia
0.000 0.551 0.449
G51.2 Melkersson's syndrome
0.000 0.551 0.449
G51.1 Geniculate ganglionitis
0.000 0.551 0.449
G56.4 Causalgia
0.000 0.562 0.437
E11.3 With ophthalmic complications
0.000 0.570 0.430
G58.7 Mononeuritis multiplex
0.000 0.571 0.429
G51.0 Bell's palsy
0.000 0.585 0.415
G54 Nerve root and plexus disorders
0.000 0.591 0.409
G52.9 Cranial nerve disorder, unspecified
0.000 0.601 0.399
G56.9 Mononeuropathy of upper limb, unspecified
0.001 0.604 0.395
E13.3 With ophthalmic complications
0.000 0.618 0.382
G53.8 Other cranial nerve disorders in other diseases classified elsewhere
0.000 0.619 0.381
G53.3 Multiple cranial nerve palsies in neoplastic disease
0.000 0.619 0.381
G53.2 Multiple cranial nerve palsies in sarcoidosis
0.000 0.619 0.381
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere
0.000 0.619 0.381
E13.8 With unspecified complications
0.000 0.623 0.377
E13.7 With multiple complications
0.000 0.623 0.377
E13.6 With other specified complications
0.000 0.623 0.377
E13.5 With peripheral circulatory complications
0.000 0.623 0.377
E13.4 With neurological complications
0.000 0.623 0.377
E13.2 With renal complications
0.000 0.623 0.377
E13.1 With ketoacidosis
0.000 0.623 0.377
E13.0 With coma
0.000 0.623 0.377
G58.0 Intercostal neuropathy
0.000 0.625 0.375
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.633 0.367
G52.7 Disorders of multiple cranial nerves
0.000 0.638 0.362
G52.0 Disorders of olfactory nerve
0.000 0.638 0.362
G50.1 Atypical facial pain
0.000 0.641 0.359
G52.1 Disorders of glossopharyngeal nerve
0.000 0.646 0.354
G51.9 Disorder of facial nerve, unspecified
0.000 0.655 0.345
E67.8 Other specified hyperalimentation
0.000 0.655 0.344
E67.3 Hypervitaminosis D
0.000 0.655 0.344
E67.2 Megavitamin-B6 syndrome
0.000 0.655 0.344
E67.1 Hypercarotenaemia
0.000 0.655 0.344
E67.0 Hypervitaminosis A
0.000 0.655 0.344
G52.2 Disorders of vagus nerve
0.000 0.660 0.340
G58.8 Other specified mononeuropathies
0.000 0.666 0.334
G57 Mononeuropathies of lower limb
0.000 0.669 0.331
G54.4 Lumbosacral root disorders, not elsewhere classified
0.000 0.676 0.323
E40-E46 Malnutrition
0.000 0.680 0.319
G52.3 Disorders of hypoglossal nerve
0.000 0.682 0.318
G53.0 Postzoster neuralgia
0.000 0.682 0.318
G52.8 Disorders of other specified cranial nerves
0.000 0.690 0.310
G54.0 Brachial plexus disorders
0.000 0.691 0.309
G54.5 Neuralgic amyotrophy
0.000 0.691 0.309
G54.7 Phantom limb syndrome without pain
0.000 0.707 0.293
G54.3 Thoracic root disorders, not elsewhere classified
0.000 0.707 0.293
G57.8 Other mononeuropathies of lower limb
0.000 0.726 0.274
E15 Nondiabetic hypoglycaemic coma
0.000 0.736 0.263
G54.2 Cervical root disorders, not elsewhere classified
0.000 0.741 0.259
G54.9 Nerve root and plexus disorder, unspecified
0.000 0.746 0.254
G58.9 Mononeuropathy, unspecified
0.000 0.746 0.254
G54.6 Phantom limb syndrome with pain
0.000 0.746 0.254
G54.8 Other nerve root and plexus disorders
0.000 0.747 0.253
G57.9 Mononeuropathy of lower limb, unspecified
0.000 0.748 0.251
G50.0 Trigeminal neuralgia
0.000 0.753 0.246
G57.4 Lesion of medial popliteal nerve
0.000 0.763 0.237
G57.2 Lesion of femoral nerve
0.000 0.763 0.237
G54.1 Lumbosacral plexus disorders
0.000 0.764 0.235
G57.0 Lesion of sciatic nerve
0.000 0.767 0.233
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.771 0.229
E45 Retarded development following protein-energy malnutrition
0.000 0.771 0.229
E43 Unspecified severe protein-energy malnutrition
0.000 0.771 0.229
E42 Marasmic kwashiorkor
0.000 0.771 0.229
E41 Nutritional marasmus
0.000 0.771 0.229
E40 Kwashiorkor
0.000 0.771 0.229
G57.3 Lesion of lateral popliteal nerve
0.000 0.773 0.227
G57.5 Tarsal tunnel syndrome
0.000 0.774 0.226
E20-E35 Disorders of other endocrine glands
0.000 0.793 0.207
E50-E64 Other nutritional deficiencies
0.000 0.794 0.206
E13.9 Without complications
0.001 0.823 0.176
E25 Adrenogenital disorders
0.000 0.826 0.174
E24 Cushing's syndrome
0.000 0.828 0.172
E16 Other disorders of pancreatic internal secretion
0.000 0.829 0.171
E23 Hypofunction and other disorders of pituitary gland
0.000 0.831 0.169
G57.1 Meralgia paraesthetica
0.000 0.832 0.168
E44.1 Mild protein-energy malnutrition
0.000 0.835 0.164
E44.0 Moderate protein-energy malnutrition
0.000 0.835 0.164
E28 Ovarian dysfunction
0.000 0.836 0.164
E56 Other vitamin deficiencies
0.000 0.838 0.162
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.849 0.151
E63 Other nutritional deficiencies
0.000 0.850 0.150
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.852 0.148
E30 Disorders of puberty, not elsewhere classified
0.000 0.852 0.148
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.852 0.148
E50 Vitamin A deficiency
0.000 0.852 0.148
E60 Dietary zinc deficiency
0.000 0.852 0.148
E59 Dietary selenium deficiency
0.000 0.852 0.148
E52 Niacin deficiency [pellagra]
0.000 0.852 0.148
E54 Ascorbic acid deficiency
0.000 0.856 0.144
E24.2 Drug-induced Cushing's syndrome
0.000 0.856 0.144
E28.2 Polycystic ovarian syndrome
0.000 0.858 0.142
E51 Thiamine deficiency
0.000 0.861 0.139
E32 Diseases of thymus
0.000 0.862 0.138
E31 Polyglandular dysfunction
0.000 0.862 0.137
E23.6 Other disorders of pituitary gland
0.000 0.863 0.137
E34 Other endocrine disorders
0.000 0.863 0.137
E24.0 Pituitary-dependent Cushing's disease
0.000 0.864 0.136
E23.0 Hypopituitarism
0.000 0.866 0.134
E20 Hypoparathyroidism
0.000 0.867 0.133
E22 Hyperfunction of pituitary gland
0.000 0.868 0.132
E56.1 Deficiency of vitamin K
0.000 0.869 0.131
E26 Hyperaldosteronism
0.000 0.869 0.131
E29 Testicular dysfunction
0.000 0.870 0.130
E24.9 Cushing's syndrome, unspecified
0.000 0.870 0.130
E23.7 Disorder of pituitary gland, unspecified
0.000 0.871 0.128
E16.1 Other hypoglycaemia
0.000 0.873 0.127
E25.9 Adrenogenital disorder, unspecified
0.000 0.875 0.125
E25.8 Other adrenogenital disorders
0.000 0.875 0.125
E61 Deficiency of other nutrient elements
0.000 0.876 0.124
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.876 0.123
E24.3 Ectopic ACTH syndrome
0.000 0.876 0.123
E24.1 Nelson's syndrome
0.000 0.876 0.123
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.877 0.123
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.877 0.123
E16.4 Abnormal secretion of gastrin
0.000 0.877 0.123
E16.3 Increased secretion of glucagon
0.000 0.877 0.123
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.878 0.121
E23.1 Drug-induced hypopituitarism
0.000 0.878 0.121
E53 Deficiency of other B group vitamins
0.000 0.881 0.119
E28.9 Ovarian dysfunction, unspecified
0.000 0.882 0.118
E28.8 Other ovarian dysfunction
0.000 0.882 0.118
E28.1 Androgen excess
0.000 0.882 0.118
E28.0 Oestrogen excess
0.000 0.882 0.118
E58 Dietary calcium deficiency
0.000 0.883 0.116
E56.9 Vitamin deficiency, unspecified
0.000 0.884 0.116
E56.8 Deficiency of other vitamins
0.000 0.884 0.116
E56.0 Deficiency of vitamin E
0.000 0.884 0.116
E63.9 Nutritional deficiency, unspecified
0.000 0.890 0.110
E34.8 Other specified endocrine disorders
0.000 0.891 0.109
E63.8 Other specified nutritional deficiencies
0.000 0.892 0.108
E63.1 Imbalance of constituents of food intake
0.000 0.892 0.108
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.892 0.108
E22.0 Acromegaly and pituitary gigantism
0.000 0.893 0.107
E30.9 Disorder of puberty, unspecified
0.000 0.893 0.106
E30.8 Other disorders of puberty
0.000 0.893 0.106
E30.1 Precocious puberty
0.000 0.893 0.106
E30.0 Delayed puberty
0.000 0.893 0.106
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.893 0.106
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.893 0.106
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.893 0.106
E50.9 Vitamin A deficiency, unspecified
0.000 0.894 0.106
E50.8 Other manifestations of vitamin A deficiency
0.000 0.894 0.106
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.894 0.106
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.894 0.106
E50.5 Vitamin A deficiency with night blindness
0.000 0.894 0.106
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.894 0.106
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.894 0.106
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.894 0.106
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.894 0.106
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.894 0.106
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.894 0.106
E64.8 Sequelae of other nutritional deficiencies
0.000 0.894 0.106
E64.3 Sequelae of rickets
0.000 0.894 0.106
E64.2 Sequelae of vitamin C deficiency
0.000 0.894 0.106
E64.1 Sequelae of vitamin A deficiency
0.000 0.894 0.106
E64.0 Sequelae of protein-energy malnutrition
0.000 0.894 0.106
E24.8 Other Cushing's syndrome
0.000 0.894 0.105
E23.2 Diabetes insipidus
0.000 0.895 0.105
E28.3 Primary ovarian failure
0.000 0.899 0.101
E51.9 Thiamine deficiency, unspecified
0.000 0.900 0.099
E51.8 Other manifestations of thiamine deficiency
0.000 0.900 0.099
E51.1 Beriberi
0.000 0.900 0.099
E32.8 Other diseases of thymus
0.000 0.901 0.099
E32.1 Abscess of thymus
0.000 0.901 0.099
E32.0 Persistent hyperplasia of thymus
0.000 0.901 0.099
E31.9 Polyglandular dysfunction, unspecified
0.000 0.901 0.099
E31.8 Other polyglandular dysfunction
0.000 0.901 0.099
E31.1 Polyglandular hyperfunction
0.000 0.901 0.099
E26.9 Hyperaldosteronism, unspecified
0.000 0.901 0.098
E34.5 Androgen resistance syndrome
0.000 0.902 0.098
E34.4 Constitutional tall stature
0.000 0.902 0.098
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.902 0.098
E34.1 Other hypersecretion of intestinal hormones
0.000 0.902 0.098
E22.1 Hyperprolactinaemia
0.000 0.903 0.097
E55 Vitamin D deficiency
0.000 0.904 0.096
E34.3 Short stature, not elsewhere classified
0.000 0.904 0.096
E20.8 Other hypoparathyroidism
0.000 0.904 0.095
E20.1 Pseudohypoparathyroidism
0.000 0.904 0.095
E20.0 Idiopathic hypoparathyroidism
0.000 0.904 0.095
E22.8 Other hyperfunction of pituitary gland
0.000 0.905 0.095
E61.2 Magnesium deficiency
0.000 0.905 0.095
E26.8 Other hyperaldosteronism
0.000 0.906 0.094
E26.1 Secondary hyperaldosteronism
0.000 0.906 0.094
E00-E07 Disorders of thyroid gland
0.000 0.907 0.093
E29.8 Other testicular dysfunction
0.000 0.907 0.093
E29.0 Testicular hyperfunction
0.000 0.907 0.093
E51.2 Wernicke's encephalopathy
0.000 0.909 0.091
E34.9 Endocrine disorder, unspecified
0.000 0.910 0.090
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.911 0.089
E32.9 Disease of thymus, unspecified
0.000 0.911 0.089
E46 Unspecified protein-energy malnutrition
0.001 0.911 0.089
E61.9 Deficiency of nutrient element, unspecified
0.000 0.911 0.089
E61.8 Deficiency of other specified nutrient elements
0.000 0.911 0.089
E61.7 Deficiency of multiple nutrient elements
0.000 0.911 0.089
E61.6 Vanadium deficiency
0.000 0.911 0.089
E61.5 Molybdenum deficiency
0.000 0.911 0.089
E61.4 Chromium deficiency
0.000 0.911 0.089
E61.3 Manganese deficiency
0.000 0.911 0.089
E61.0 Copper deficiency
0.000 0.911 0.089
E53.9 Vitamin B deficiency, unspecified
0.000 0.911 0.089
E31.0 Autoimmune polyglandular failure
0.000 0.912 0.088
E29.1 Testicular hypofunction
0.000 0.914 0.086
E53.1 Pyridoxine deficiency
0.000 0.915 0.085
E53.0 Riboflavin deficiency
0.000 0.915 0.085
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.915 0.085
E16.2 Hypoglycaemia, unspecified
0.000 0.915 0.085
E34.0 Carcinoid syndrome
0.000 0.916 0.084
E29.9 Testicular dysfunction, unspecified
0.000 0.916 0.083
E06 Thyroiditis
0.000 0.917 0.083
E20.9 Hypoparathyroidism, unspecified
0.000 0.920 0.080
E06.3 Autoimmune thyroiditis
0.000 0.929 0.071
E06.9 Thyroiditis, unspecified
0.000 0.929 0.071
E55.0 Rickets, active
0.000 0.931 0.069
F33.1 Recurrent depressive disorder, current episode moderate
0.000 0.932 0.068
E26.0 Primary hyperaldosteronism
0.000 0.932 0.068
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.933 0.067
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.933 0.067
E00 Congenital iodine-deficiency syndrome
0.000 0.933 0.067
F33 Recurrent depressive disorder
0.000 0.933 0.067
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.939 0.061
E06.4 Drug-induced thyroiditis
0.000 0.940 0.059
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.940 0.059
E06.0 Acute thyroiditis
0.000 0.940 0.059
F33.9 Recurrent depressive disorder, unspecified
0.000 0.940 0.060
E06.1 Subacute thyroiditis
0.000 0.942 0.058
E27 Other disorders of adrenal gland
0.000 0.942 0.057
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.945 0.055
E06.5 Other chronic thyroiditis
0.000 0.945 0.055
F33.0 Recurrent depressive disorder, current episode mild
0.000 0.945 0.055
E61.1 Iron deficiency
0.000 0.945 0.055
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.952 0.048
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.952 0.048
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.952 0.048
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.952 0.048
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.952 0.048
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.952 0.048
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.952 0.048
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.952 0.048
E53.8 Deficiency of other specified B group vitamins
0.000 0.952 0.048
F33.4 Recurrent depressive disorder, currently in remission
0.000 0.953 0.047
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.000 0.954 0.046
E27.8 Other specified disorders of adrenal gland
0.000 0.955 0.045
F33.8 Other recurrent depressive disorders
0.000 0.955 0.045
E03 Other hypothyroidism
0.000 0.956 0.044
E27.5 Adrenomedullary hyperfunction
0.000 0.958 0.041
E27.0 Other adrenocortical overactivity
0.000 0.958 0.041
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.960 0.040
E07 Other disorders of thyroid
0.000 0.961 0.039
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.961 0.039
E27.2 Addisonian crisis
0.000 0.962 0.038
E03.8 Other specified hypothyroidism
0.000 0.966 0.034
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.966 0.034
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.966 0.034
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.967 0.033
E27.9 Disorder of adrenal gland, unspecified
0.000 0.967 0.033
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.967 0.032
E03.5 Myxoedema coma
0.000 0.968 0.032
E03.4 Atrophy of thyroid (acquired)
0.000 0.968 0.032
E03.3 Postinfectious hypothyroidism
0.000 0.968 0.032
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.970 0.030
E05.5 Thyroid crisis or storm
0.000 0.972 0.028
E05.4 Thyrotoxicosis factitia
0.000 0.972 0.028
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.972 0.028
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.972 0.028
E07.1 Dyshormogenetic goitre
0.000 0.972 0.028
E07.0 Hypersecretion of calcitonin
0.000 0.972 0.028
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.973 0.027
E03.1 Congenital hypothyroidism without goitre
0.000 0.973 0.027
E05.9 Thyrotoxicosis, unspecified
0.000 0.974 0.026
G57.6 Lesion of plantar nerve
0.000 0.975 0.025
M25.5 Pain in joint
0.000 0.976 0.024
E21.4 Other specified disorders of parathyroid gland
0.000 0.976 0.024
M25.57 Pain in joint (Ankle and foot)
0.000 0.976 0.024
M25.56 Pain in joint (Lower leg)
0.000 0.976 0.024
E07.8 Other specified disorders of thyroid
0.000 0.976 0.023
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.023 0.977 0.000
M85.8 Other specified disorders of bone density and structure
0.023 0.977 0.000
E05.8 Other thyrotoxicosis
0.000 0.978 0.021
E21.3 Hyperparathyroidism, unspecified
0.000 0.978 0.022
M25.53 Pain in joint (Forearm)
0.000 0.979 0.021
M25.58 Pain in joint (Other)
0.000 0.979 0.021
M80.0 Postmenopausal osteoporosis with pathological fracture
0.021 0.979 0.000
E21.2 Other hyperparathyroidism
0.000 0.979 0.020
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.979 0.020
M85 Other disorders of bone density and structure
0.020 0.979 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.020 0.980 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.020 0.980 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.980 0.019
M25.51 Pain in joint (Shoulder region)
0.000 0.981 0.019
M80 Osteoporosis with pathological fracture
0.019 0.981 0.000
M80-M85 Disorders of bone density and structure
0.019 0.981 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.019 0.981 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.018 0.981 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.018 0.982 0.000
M25.59 Pain in joint (Site unspecified)
0.000 0.982 0.018
E55.9 Vitamin D deficiency, unspecified
0.000 0.982 0.017
M85.0 Fibrous dysplasia (monostotic)
0.017 0.982 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.017 0.983 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.016 0.984 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.016 0.984 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.016 0.984 0.000
M82 Osteoporosis in diseases classified elsewhere
0.016 0.984 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.016 0.984 0.000
M85.2 Hyperostosis of skull
0.015 0.984 0.000
M85.9 Disorder of bone density and structure, unspecified
0.015 0.984 0.000
M85.4 Solitary bone cyst
0.015 0.985 0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)
0.015 0.985 0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)
0.015 0.985 0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)
0.015 0.985 0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)
0.015 0.985 0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)
0.015 0.985 0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)
0.015 0.985 0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)
0.015 0.985 0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)
0.015 0.985 0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)
0.015 0.985 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.015 0.985 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.015 0.985 0.000
M85.5 Aneurysmal bone cyst
0.015 0.985 0.000
M85.3 Osteitis condensans
0.015 0.985 0.000
M85.1 Skeletal fluorosis
0.015 0.985 0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.015 0.985 0.000
M82.1 Osteoporosis in endocrine disorders
0.015 0.985 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.014 0.986 0.000
M81 Osteoporosis without pathological fracture
0.014 0.986 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.986 0.014
M83 Adult osteomalacia
0.014 0.986 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.014 0.986 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.014 0.986 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.014 0.986 0.000
E87.5 Hyperkalaemia
0.000 0.986 0.014
M80.5 Idiopathic osteoporosis with pathological fracture
0.014 0.986 0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)
0.013 0.987 0.000
M80.8 Other osteoporosis with pathological fracture
0.013 0.987 0.000
E27.1 Primary adrenocortical insufficiency
0.001 0.987 0.012
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)
0.013 0.987 0.000
M85.08 Fibrous dysplasia (monostotic) (Other)
0.013 0.987 0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)
0.013 0.987 0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)
0.013 0.987 0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)
0.013 0.987 0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)
0.013 0.987 0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)
0.013 0.987 0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)
0.013 0.987 0.000
M84 Disorders of continuity of bone
0.013 0.987 0.000
J32.0 Chronic maxillary sinusitis
0.000 0.988 0.012
M85.20 Hyperostosis of skull-Mult sites
0.012 0.988 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.012 0.988 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.012 0.988 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.012 0.988 0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)
0.012 0.988 0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)
0.012 0.988 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.012 0.988 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.988 0.012
E04 Other non-toxic goitre
0.000 0.988 0.012
Q38.7 Pharyngeal pouch
0.000 0.988 0.012
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.011 0.989 0.000
M85.29 Hyperostosis of skull-Site unspec
0.011 0.989 0.000
M85.28 Hyperostosis of skull-Other
0.011 0.989 0.000
M85.27 Hyperostosis of skull-Ankle/Foot
0.011 0.989 0.000
M85.26 Hyperostosis of skull-Lower Leg
0.011 0.989 0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh
0.011 0.989 0.000
M85.24 Hyperostosis of skull-Hand
0.011 0.989 0.000
M85.23 Hyperostosis of skull-Forearm
0.011 0.989 0.000
M85.21 Hyperostosis of skull-Shldr region
0.011 0.989 0.000
M85.98 Disorder of bone density and structure, unspecified (Other)
0.011 0.989 0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)
0.011 0.989 0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)
0.011 0.989 0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)
0.011 0.989 0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)
0.011 0.989 0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)
0.011 0.989 0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)
0.011 0.989 0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)
0.011 0.989 0.000
M85.22 Hyperostosis of skull-Upper arm
0.011 0.989 0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)
0.011 0.989 0.000
G63.2 Diabetic polyneuropathy
0.000 0.989 0.011
M85.49 Solitary bone cyst (Site unspecified)
0.011 0.989 0.000
M85.48 Solitary bone cyst (Other)
0.011 0.989 0.000
M85.46 Solitary bone cyst (Lower leg)
0.011 0.989 0.000
M85.44 Solitary bone cyst (Hand)
0.011 0.989 0.000
M85.43 Solitary bone cyst (Forearm)
0.011 0.989 0.000
M85.42 Solitary bone cyst (Upper arm)
0.011 0.989 0.000
M85.41 Solitary bone cyst (Shoulder region)
0.011 0.989 0.000
M85.40 Solitary bone cyst (Multiple sites)
0.011 0.989 0.000
M83.8 Other adult osteomalacia
0.011 0.989 0.000
M81.0 Postmenopausal osteoporosis
0.011 0.989 0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.011 0.989 0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.011 0.989 0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.011 0.989 0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.011 0.989 0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.011 0.989 0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.011 0.989 0.000
M81.9 Osteoporosis, unspecified
0.011 0.989 0.000
M85.19 Skeletal fluorosis (Site unspecified)
0.011 0.989 0.000
M85.18 Skeletal fluorosis (Other)
0.011 0.989 0.000
M85.17 Skeletal fluorosis (Ankle and foot)
0.011 0.989 0.000
M85.16 Skeletal fluorosis (Lower leg)
0.011 0.989 0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)
0.011 0.989 0.000
M85.14 Skeletal fluorosis (Hand)
0.011 0.989 0.000
M85.13 Skeletal fluorosis (Forearm)
0.011 0.989 0.000
M85.12 Skeletal fluorosis (Upper arm)
0.011 0.989 0.000
M85.11 Skeletal fluorosis (Shoulder region)
0.011 0.989 0.000
M85.10 Skeletal fluorosis (Multiple sites)
0.011 0.989 0.000
M85.39 Osteitis condensans (Site unspecified)
0.011 0.989 0.000
M85.38 Osteitis condensans (Other)
0.011 0.989 0.000
M85.37 Osteitis condensans (Ankle and foot)
0.011 0.989 0.000
M85.36 Osteitis condensans (Lower leg)
0.011 0.989 0.000
M85.35 Osteitis condensans (Pelvic region and thigh)
0.011 0.989 0.000
M85.34 Osteitis condensans (Hand)
0.011 0.989 0.000
M85.33 Osteitis condensans (Forearm)
0.011 0.989 0.000
M85.32 Osteitis condensans (Upper arm)
0.011 0.989 0.000
M85.31 Osteitis condensans (Shoulder region)
0.011 0.989 0.000
M85.30 Osteitis condensans (Multiple sites)
0.011 0.989 0.000
M85.59 Aneurysmal bone cyst (Site unspecified)
0.011 0.989 0.000
M85.58 Aneurysmal bone cyst (Other)
0.011 0.989 0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)
0.011 0.989 0.000
M85.56 Aneurysmal bone cyst (Lower leg)
0.011 0.989 0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)
0.011 0.989 0.000
M85.54 Aneurysmal bone cyst (Hand)
0.011 0.989 0.000
M85.53 Aneurysmal bone cyst (Forearm)
0.011 0.989 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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