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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2281727
log Bayes Factor = 2.07378
Chromosome 17   position 2,117,945  (GRCh37) Explore rs2281727 on Ensembl!
Variant rs2281727 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
0.981 0.019 0.000
I25 Chronic ischaemic heart disease
0.959 0.041 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.953 0.047 0.000
I25.5 Ischaemic cardiomyopathy
0.817 0.183 0.000
I25.4 Coronary artery aneurysm
0.803 0.197 0.000
I25.3 Aneurysm of heart
0.764 0.236 0.000
I25.6 Silent myocardial ischaemia
0.688 0.312 0.000
I25.2 Old myocardial infarction
0.685 0.315 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.570 0.430 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.431 0.569 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.425 0.575 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.416 0.584 0.000
M23 Internal derangement of knee
0.401 0.599 0.000
M17.9 Gonarthrosis, unspecified
0.380 0.620 0.000
M23.3 Other meniscus derangements
0.377 0.623 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.364 0.636 0.000
M17 Gonarthrosis [arthrosis of knee]
0.349 0.651 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.339 0.661 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.338 0.662 0.000
M23.9 Internal derangement of knee, unspecified
0.330 0.669 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.329 0.671 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.323 0.677 0.000
M17.1 Other primary gonarthrosis
0.305 0.695 0.000
M23.4 Loose body in knee
0.301 0.699 0.000
M17.0 Primary gonarthrosis, bilateral
0.299 0.701 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.298 0.702 0.000
M17.5 Other secondary gonarthrosis
0.297 0.703 0.000
M23.8 Other internal derangements of knee
0.292 0.708 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.292 0.708 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.274 0.726 0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.272 0.728 0.000
M23.1 Discoid meniscus (congenital)
0.270 0.730 0.000
M23.37 Other meniscus derangements-Capsular lig
0.270 0.730 0.000
M23.0 Cystic meniscus
0.270 0.730 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.269 0.731 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.269 0.731 0.000
M23.43 Loose body in knee-Med lig/oth men
0.268 0.732 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.264 0.736 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.264 0.736 0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)
0.261 0.738 0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)
0.261 0.738 0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp
0.261 0.738 0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn
0.261 0.738 0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.261 0.738 0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.261 0.738 0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.261 0.738 0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)
0.261 0.738 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.261 0.739 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.253 0.747 0.000
M20-M25 Other joint disorders
0.249 0.751 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.248 0.752 0.000
I20-I25 Ischaemic heart diseases
0.246 0.754 0.000
M15-M19 Arthrosis
0.246 0.754 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.245 0.755 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.242 0.758 0.000
M43 Other deforming dorsopathies
0.242 0.758 0.000
M40-M43 Deforming dorsopathies
0.241 0.759 0.000
M43.1 Spondylolisthesis
0.239 0.761 0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)
0.237 0.763 0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)
0.237 0.763 0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)
0.237 0.763 0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.237 0.763 0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.237 0.763 0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)
0.237 0.763 0.000
M86-M90 Other osteopathies
0.236 0.764 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.234 0.766 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.233 0.767 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.232 0.767 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.232 0.768 0.000
M65-M68 Disorders of synovium and tendon
0.232 0.768 0.000
M65 Synovitis and tenosynovitis
0.231 0.769 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.229 0.771 0.000
M89 Other disorders of bone
0.227 0.773 0.000
I22 Subsequent myocardial infarction
0.227 0.773 0.000
M23.5 Chronic instability of knee
0.223 0.777 0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)
0.223 0.777 0.000
M80-M85 Disorders of bone density and structure
0.221 0.779 0.000
M23.47 Loose body in knee-Capsular lig
0.216 0.784 0.000
M23.45 Loose body in knee-Pst hrn lat men
0.216 0.784 0.000
M23.44 Loose body in knee-Lat lig/ant men
0.216 0.784 0.000
M23.42 Loose body in knee-Pst lig/hrn men
0.216 0.784 0.000
M23.40 Loose body in knee-Mult sites
0.214 0.786 0.000
M43.2 Other fusion of spine
0.214 0.786 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.213 0.787 0.000
M81 Osteoporosis without pathological fracture
0.212 0.788 0.000
M24 Other specific joint derangements
0.211 0.789 0.000
M86 Osteomyelitis
0.210 0.790 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.209 0.790 0.000
M43.12 Spondylolisthesis (Cervical region)
0.209 0.791 0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.207 0.793 0.000
M23.46 Loose body in knee-O/unsp lat men
0.204 0.796 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.200 0.800 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.199 0.801 0.000
M81.4 Drug-induced osteoporosis
0.199 0.801 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.198 0.802 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.196 0.803 0.000
M34 Systemic sclerosis
0.196 0.803 0.000
M17.3 Other posttraumatic gonarthrosis
0.196 0.804 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.196 0.804 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.195 0.805 0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)
0.194 0.806 0.000
M23.17 Discoid meniscus (congenital)-Capsular lig
0.194 0.806 0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)
0.194 0.806 0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.194 0.806 0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)
0.194 0.806 0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.194 0.806 0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.194 0.806 0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)
0.194 0.806 0.000
M89.8 Other specified disorders of bone
0.194 0.806 0.000
M23.07 Cystic meniscus-Capsular lig
0.194 0.806 0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)
0.194 0.806 0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.194 0.806 0.000
M23.00 Cystic meniscus (Multiple sites)
0.194 0.806 0.000
M43.29 Other fusion of spine (Site unspecified)
0.193 0.806 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.193 0.807 0.000
M86.9 Osteomyelitis, unspecified
0.192 0.808 0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.192 0.808 0.000
M15 Polyarthrosis
0.192 0.808 0.000
M23.41 Loose body in knee-Ant lig/hrn men
0.191 0.809 0.000
M24.0 Loose body in joint
0.191 0.809 0.000
M90 Osteopathies in diseases classified elsewhere
0.190 0.810 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.190 0.810 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.189 0.811 0.000
M89.5 Osteolysis
0.188 0.811 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.188 0.812 0.000
M32 Systemic lupus erythematosus
0.188 0.812 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.188 0.812 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.188 0.812 0.000
I24 Other acute ischaemic heart diseases
0.187 0.813 0.000
M89.0 Algoneurodystrophy
0.186 0.814 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.186 0.814 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.186 0.814 0.000
M42 Spinal osteochondrosis
0.184 0.816 0.000
M65.2 Calcific tendinitis
0.183 0.817 0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.182 0.818 0.000
M23.49 Loose body in knee-Unspec lig/men
0.182 0.818 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.180 0.819 0.000
M89.3 Hypertrophy of bone
0.180 0.820 0.000
M43.9 Deforming dorsopathy, unspecified
0.180 0.820 0.000
M43.8 Other specified deforming dorsopathies
0.180 0.820 0.000
M24.1 Other articular cartilage disorders
0.180 0.820 0.000
M81.2 Osteoporosis of disuse
0.179 0.821 0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.178 0.822 0.000
M65.3 Trigger finger
0.178 0.822 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.177 0.823 0.000
M80 Osteoporosis with pathological fracture
0.176 0.824 0.000
M24.5 Contracture of joint
0.175 0.825 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.174 0.826 0.000
M43.5 Other recurrent vertebral subluxation
0.174 0.826 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.174 0.826 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.174 0.826 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.174 0.826 0.000
I23 Certain current complications following acute myocardial infarction
0.173 0.827 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.172 0.828 0.000
M22 Disorders of patella
0.172 0.828 0.000
M40 Kyphosis and lordosis
0.172 0.828 0.000
M43.6 Torticollis
0.171 0.828 0.000
M31 Other necrotising vasculopathies
0.171 0.829 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.171 0.829 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.171 0.829 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.171 0.829 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.171 0.829 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.171 0.829 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.171 0.829 0.000
M81.9 Osteoporosis, unspecified
0.171 0.829 0.000
M82 Osteoporosis in diseases classified elsewhere
0.170 0.830 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.168 0.832 0.000
I22.8 Subsequent myocardial infarction of other sites
0.168 0.832 0.000
M21 Other acquired deformities of limbs
0.167 0.833 0.000
M43.0 Spondylolysis
0.167 0.833 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.167 0.833 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.166 0.834 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.166 0.834 0.000
M65.0 Abscess of tendon sheath
0.166 0.834 0.000
M24.07 Loose body in joint (Ankle and foot)
0.166 0.834 0.000
M86.6 Other chronic osteomyelitis
0.165 0.835 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.164 0.836 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.164 0.836 0.000
M89.6 Osteopathy after poliomyelitis
0.163 0.837 0.000
M89.2 Other disorders of bone development and growth
0.163 0.837 0.000
M89.1 Epiphyseal arrest
0.163 0.837 0.000
M24.06 Loose body in joint-Lower leg
0.163 0.837 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.163 0.837 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.162 0.838 0.000
M24.2 Disorder of ligament
0.161 0.839 0.000
M89.55 Osteolysis (Pelvic region and thigh)
0.161 0.839 0.000
M22.4 Chondromalacia patellae
0.160 0.840 0.000
M23.57 Chronic instability of knee (Capsular ligament)
0.160 0.840 0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)
0.160 0.840 0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)
0.160 0.840 0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.160 0.840 0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.160 0.840 0.000
M23.50 Chronic instability of knee (Multiple sites)
0.160 0.840 0.000
M89.04 Algoneurodystrophy (Hand)
0.160 0.840 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.159 0.841 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.158 0.842 0.000
M81.98 Osteoporosis, unspecified (Other)
0.158 0.842 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.158 0.842 0.000
M83 Adult osteomalacia
0.157 0.843 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.156 0.844 0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)
0.156 0.844 0.000
M89.9 Disorder of bone, unspecified
0.156 0.844 0.000
M81.20 Osteoporosis of disuse (Multiple sites)
0.155 0.845 0.000
M21.3 Wrist or foot drop (acquired)
0.155 0.845 0.000
M34.1 CR(E)ST syndrome
0.155 0.845 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.155 0.845 0.000
M34.0 Progressive systemic sclerosis
0.154 0.846 0.000
M15.4 Erosive (osteo)arthrosis
0.153 0.846 0.000
M43.28 Other fusion of spine (Sacral and sacrococcygeal region)
0.153 0.847 0.000
M43.27 Other fusion of spine (Lumbosacral region)
0.153 0.847 0.000
M43.26 Other fusion of spine (Lumbar region)
0.153 0.847 0.000
M43.25 Other fusion of spine (Thoracolumbar region)
0.153 0.847 0.000
M43.24 Other fusion of spine (Thoracic region)
0.153 0.847 0.000
M43.23 Other fusion of spine (Cervicothoracic region)
0.153 0.847 0.000
M43.22 Other fusion of spine (Cervical region)
0.153 0.847 0.000
M43.21 Other fusion of spine (Occipito-atlanto-axial region)
0.153 0.847 0.000
M43.20 Other fusion of spine (Multiple sites in spine)
0.153 0.847 0.000
M89.03 Algoneurodystrophy (Forearm)
0.153 0.847 0.000
M00-M03 Infectious arthropathies
0.153 0.847 0.000
M81.8 Other osteoporosis
0.152 0.848 0.000
M81.6 Localised osteoporosis [Lequesne]
0.152 0.848 0.000
M81.5 Idiopathic osteoporosis
0.152 0.848 0.000
M81.1 Postoophorectomy osteoporosis
0.152 0.848 0.000
M24.9 Joint derangement, unspecified
0.152 0.848 0.000
M88 Paget's disease of bone [osteitis deformans]
0.152 0.848 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.151 0.849 0.000
M91-M94 Chondropathies
0.151 0.849 0.000
M86.1 Other acute osteomyelitis
0.151 0.849 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.151 0.849 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.151 0.849 0.000
M86.3 Chronic multifocal osteomyelitis
0.151 0.849 0.000
M86.2 Subacute osteomyelitis
0.151 0.849 0.000
M86.0 Acute haematogenous osteomyelitis
0.151 0.849 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.150 0.850 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.150 0.850 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.149 0.851 0.000
M89.84 Other specified disorders of bone (Hand)
0.149 0.851 0.000
M65.21 Calcific tendinitis (Shoulder region)
0.148 0.852 0.000
M43.09 Spondylolysis (Site unspecified)
0.148 0.852 0.000
M24.04 Loose body in joint (Hand)
0.147 0.853 0.000
M34.8 Other forms of systemic sclerosis
0.147 0.853 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.147 0.853 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.146 0.854 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.146 0.854 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.146 0.854 0.000
M85 Other disorders of bone density and structure
0.145 0.854 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.145 0.855 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.145 0.855 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.145 0.855 0.000
M86.98 Osteomyelitis, unspecified (Other)
0.145 0.855 0.000
M65.1 Other infective (teno)synovitis
0.145 0.855 0.000
M66 Spontaneous rupture of synovium and tendon
0.145 0.855 0.000
M33 Dermatopolymyositis
0.144 0.856 0.000
M22.3 Other derangements of patella
0.144 0.856 0.000
M81.0 Postmenopausal osteoporosis
0.144 0.856 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.143 0.856 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.143 0.857 0.000
M81.48 Drug-induced osteoporosis (Other)
0.142 0.857 0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.142 0.857 0.000
M81.46 Drug-induced osteoporosis (Lower leg)
0.142 0.857 0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.142 0.857 0.000
M81.44 Drug-induced osteoporosis (Hand)
0.142 0.857 0.000
M81.43 Drug-induced osteoporosis (Forearm)
0.142 0.857 0.000
M81.42 Drug-induced osteoporosis (Upper arm)
0.142 0.857 0.000
M81.41 Drug-induced osteoporosis (Shoulder region)
0.142 0.857 0.000
M42.0 Juvenile osteochondrosis of spine
0.142 0.857 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.142 0.858 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.142 0.858 0.000
M89.37 Hypertrophy of bone (Ankle and foot)
0.142 0.858 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.141 0.859 0.000
M36.3 Arthropathy in other blood disorders
0.141 0.859 0.000
M36.2 Haemophilic arthropathy
0.141 0.859 0.000
M36.1 Arthropathy in neoplastic disease
0.141 0.859 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.141 0.859 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.141 0.859 0.000
M15.9 Polyarthrosis, unspecified
0.141 0.859 0.000
M30 Polyarteritis nodosa and related conditions
0.141 0.859 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.140 0.860 0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)
0.140 0.860 0.000
M65.34 Trigger finger-Hand
0.140 0.860 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.139 0.861 0.000
M89.89 Other specified disorders of bone (Site unspecified)
0.139 0.861 0.000
M89.82 Other specified disorders of bone (Upper arm)
0.139 0.861 0.000
M89.80 Other specified disorders of bone (Multiple sites)
0.139 0.861 0.000
M24.52 Contracture of joint (Upper arm)
0.139 0.861 0.000
M86.93 Osteomyelitis, unspecified (Forearm)
0.138 0.862 0.000
M86.92 Osteomyelitis, unspecified (Upper arm)
0.138 0.862 0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.138 0.862 0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.138 0.862 0.000
M24.03 Loose body in joint (Forearm)
0.138 0.862 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.138 0.862 0.000
M15.0 Primary generalised (osteo)arthrosis
0.138 0.862 0.000
M89.83 Other specified disorders of bone (Forearm)
0.138 0.862 0.000
M15.1 Heberden's nodes (with arthropathy)
0.137 0.862 0.000
M24.6 Ankylosis of joint
0.137 0.863 0.000
M24.56 Contracture of joint (Lower leg)
0.137 0.863 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.137 0.863 0.000
M24.09 Loose body in joint (Site unspecified)
0.137 0.863 0.000
M24.08 Loose body in joint (Other)
0.137 0.863 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.137 0.863 0.000
M24.00 Loose body in joint (Multiple sites)
0.137 0.863 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.137 0.863 0.000
M90.6 Osteitis deformans in neoplastic disease
0.137 0.863 0.000
M90.5 Osteonecrosis in other diseases classified elsewhere
0.137 0.863 0.000
M90.4 Osteonecrosis due to heamoglobinopathy
0.137 0.863 0.000
M90.3 Osteonecrosis in caisson disease
0.137 0.863 0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.137 0.863 0.000
M90.0 Tuberculosis of bone
0.137 0.863 0.000
M90.7 Fracture of bone in neoplastic disease
0.136 0.864 0.000
M43.99 Deforming dorsopathy, unspecified (Site unspecified)
0.136 0.864 0.000
M89.38 Hypertrophy of bone (Other)
0.136 0.864 0.000
M43.86 Other specified deforming dorsopathies (Lumbar region)
0.135 0.865 0.000
M89.59 Osteolysis (Site unspecified)
0.135 0.865 0.000
M89.58 Osteolysis (Other)
0.135 0.865 0.000
M89.57 Osteolysis (Ankle and foot)
0.135 0.865 0.000
M89.56 Osteolysis (Lower leg)
0.135 0.865 0.000
M89.54 Osteolysis (Hand)
0.135 0.865 0.000
M89.53 Osteolysis (Forearm)
0.135 0.865 0.000
M89.52 Osteolysis (Upper arm)
0.135 0.865 0.000
M89.51 Osteolysis (Shoulder region)
0.135 0.865 0.000
M89.50 Osteolysis (Multiple sites)
0.135 0.865 0.000
M21.9 Acquired deformity of limb, unspecified
0.135 0.865 0.000
M24.54 Contracture of joint (Hand)
0.135 0.865 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.135 0.865 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.135 0.865 0.000
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)
0.135 0.865 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.134 0.866 0.000
M32.8 Other forms of systemic lupus erythematosus
0.134 0.866 0.000
M82.1 Osteoporosis in endocrine disorders
0.134 0.866 0.000
M40.2 Other and unspecified kyphosis
0.134 0.866 0.000
M89.08 Algoneurodystrophy (Other)
0.133 0.866 0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)
0.133 0.866 0.000
M89.02 Algoneurodystrophy (Upper arm)
0.133 0.866 0.000
M89.01 Algoneurodystrophy (Shoulder region)
0.133 0.866 0.000
M89.00 Algoneurodystrophy (Multiple sites)
0.133 0.866 0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)
0.133 0.867 0.000
M89.48 Other hypertrophic osteoarthropathy (Other)
0.133 0.867 0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)
0.133 0.867 0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)
0.133 0.867 0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)
0.133 0.867 0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)
0.133 0.867 0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)
0.133 0.867 0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)
0.133 0.867 0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)
0.133 0.867 0.000
M42.9 Spinal osteochondrosis, unspecified
0.132 0.868 0.000
M42.1 Adult osteochondrosis of spine
0.132 0.868 0.000
M41 Scoliosis
0.131 0.868 0.000
M65.29 Calcific tendinitis (Site unspecified)
0.131 0.869 0.000
M65.28 Calcific tendinitis (Other)
0.131 0.869 0.000
M65.27 Calcific tendinitis (Ankle and foot)
0.131 0.869 0.000
M65.26 Calcific tendinitis (Lower leg)
0.131 0.869 0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)
0.131 0.869 0.000
M65.24 Calcific tendinitis (Hand)
0.131 0.869 0.000
M65.23 Calcific tendinitis (Forearm)
0.131 0.869 0.000
M65.22 Calcific tendinitis (Upper arm)
0.131 0.869 0.000
M65.20 Calcific tendinitis (Multiple sites)
0.131 0.869 0.000
M31.8 Other specified necrotising vasculopathies
0.131 0.869 0.000
M24.01 Loose body in joint (Shoulder region)
0.131 0.869 0.000
M15.3 Secondary multiple arthrosis
0.131 0.869 0.000
M24.23 Disorder of ligament (Forearm)
0.131 0.869 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.131 0.869 0.000
I24.1 Dressler's syndrome
0.130 0.870 0.000
M89.39 Hypertrophy of bone (Site unspecified)
0.129 0.870 0.000
M89.36 Hypertrophy of bone (Lower leg)
0.129 0.870 0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)
0.129 0.870 0.000
M89.34 Hypertrophy of bone (Hand)
0.129 0.870 0.000
M89.33 Hypertrophy of bone (Forearm)
0.129 0.870 0.000
M89.32 Hypertrophy of bone (Upper arm)
0.129 0.870 0.000
M89.31 Hypertrophy of bone (Shoulder region)
0.129 0.870 0.000
M89.30 Hypertrophy of bone (Multiple sites)
0.129 0.870 0.000
M43.98 Deforming dorsopathy, unspecified (Sacral and sacrococcygeal region)
0.129 0.871 0.000
M43.97 Deforming dorsopathy, unspecified (Lumbosacral region)
0.129 0.871 0.000
M43.96 Deforming dorsopathy, unspecified (Lumbar region)
0.129 0.871 0.000
M43.95 Deforming dorsopathy, unspecified (Thoracolumbar region)
0.129 0.871 0.000
M43.94 Deforming dorsopathy, unspecified (Thoracic region)
0.129 0.871 0.000
M43.93 Deforming dorsopathy, unspecified (Cervicothoracic region)
0.129 0.871 0.000
M43.92 Deforming dorsopathy, unspecified (Cervical region)
0.129 0.871 0.000
M43.91 Deforming dorsopathy, unspecified (Occipito-atlanto-axial region)
0.129 0.871 0.000
M43.90 Deforming dorsopathy, unspecified (Multiple sites in spine)
0.129 0.871 0.000
M43.89 Other specified deforming dorsopathies (Site unspecified)
0.129 0.871 0.000
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)
0.129 0.871 0.000
M43.87 Other specified deforming dorsopathies (Lumbosacral region)
0.129 0.871 0.000
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)
0.129 0.871 0.000
M43.84 Other specified deforming dorsopathies (Thoracic region)
0.129 0.871 0.000
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)
0.129 0.871 0.000
M43.82 Other specified deforming dorsopathies (Cervical region)
0.129 0.871 0.000
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)
0.129 0.871 0.000
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)
0.129 0.871 0.000
M86.8 Other osteomyelitis
0.129 0.871 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.129 0.871 0.000
M24.18 Other articular cartilage disorders (Other)
0.129 0.871 0.000
M24.14 Other articular cartilage disorders (Hand)
0.129 0.871 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.129 0.871 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.129 0.871 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.129 0.871 0.000
M81.29 Osteoporosis of disuse (Site unspecified)
0.128 0.871 0.000
M81.28 Osteoporosis of disuse (Other)
0.128 0.871 0.000
M81.27 Osteoporosis of disuse (Ankle and foot)
0.128 0.871 0.000
M81.26 Osteoporosis of disuse (Lower leg)
0.128 0.871 0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)
0.128 0.871 0.000
M81.24 Osteoporosis of disuse (Hand)
0.128 0.871 0.000
M81.23 Osteoporosis of disuse (Forearm)
0.128 0.871 0.000
M81.22 Osteoporosis of disuse (Upper arm)
0.128 0.871 0.000
M81.21 Osteoporosis of disuse (Shoulder region)
0.128 0.871 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.128 0.872 0.000
M24.57 Contracture of joint (Ankle and foot)
0.128 0.872 0.000
M65.39 Trigger finger-Site unspec
0.128 0.872 0.000
M65.38 Trigger finger-Other
0.128 0.872 0.000
M65.37 Trigger finger-Ankle/foot
0.128 0.872 0.000
M65.36 Trigger finger-Lower leg
0.128 0.872 0.000
M65.35 Trigger finger-Pelvic/thigh
0.128 0.872 0.000
M65.33 Trigger finger-Forearm
0.128 0.872 0.000
M65.32 Trigger finger-Upper arm
0.128 0.872 0.000
M65.31 Trigger finger-Shldr region
0.128 0.872 0.000
M65.30 Trigger finger-Mult sites
0.128 0.872 0.000
M24.7 Protrusio acetabuli
0.127 0.873 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.127 0.873 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.127 0.873 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.127 0.873 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.127 0.873 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.127 0.873 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.127 0.873 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.127 0.873 0.000
M24.59 Contracture of joint (Site unspecified)
0.126 0.874 0.000
M24.58 Contracture of joint (Other)
0.126 0.874 0.000
M24.53 Contracture of joint (Forearm)
0.126 0.874 0.000
M24.50 Contracture of joint (Multiple sites)
0.126 0.874 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.125 0.875 0.000
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)
0.125 0.875 0.000
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)
0.125 0.875 0.000
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)
0.125 0.875 0.000
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)
0.125 0.875 0.000
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)
0.125 0.875 0.000
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)
0.125 0.875 0.000
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)
0.125 0.875 0.000
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)
0.125 0.875 0.000
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)
0.125 0.875 0.000
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)
0.125 0.875 0.000
M43.49 Other recurrent atlantoaxial subluxation-Site unspe
0.125 0.875 0.000
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ
0.125 0.875 0.000
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral
0.125 0.875 0.000
M43.46 Other recurrent atlantoaxial subluxation-Lumbar
0.125 0.875 0.000
M43.45 Other recurrent atlantoaxial subluxation-Thoracolumbar
0.125 0.875 0.000
M43.44 Other recurrent atlantoaxial subluxation-Thoracic
0.125 0.875 0.000
M43.43 Other recurrent atlantoaxial subluxation-Cervicothoracic
0.125 0.875 0.000
M43.42 Other recurrent atlantoaxial subluxation-Cervical
0.125 0.875 0.000
M43.41 Other recurrent atlantoaxial subluxation-Occipit-atl-axl
0.125 0.875 0.000
M43.40 Other recurrent atlantoaxial subluxation-Mult site
0.125 0.875 0.000
M43.59 Other recurrent vertebral subluxation (Site unspecified)
0.125 0.875 0.000
M43.58 Other recurrent vertebral subluxation (Sacral and sacrococcygeal region)
0.125 0.875 0.000
M43.57 Other recurrent vertebral subluxation (Lumbosacral region)
0.125 0.875 0.000
M43.56 Other recurrent vertebral subluxation (Lumbar region)
0.125 0.875 0.000
M43.55 Other recurrent vertebral subluxation (Thoracolumbar region)
0.125 0.875 0.000
M43.54 Other recurrent vertebral subluxation (Thoracic region)
0.125 0.875 0.000
M43.53 Other recurrent vertebral subluxation (Cervicothoracic region)
0.125 0.875 0.000
M43.52 Other recurrent vertebral subluxation (Cervical region)
0.125 0.875 0.000
M43.51 Other recurrent vertebral subluxation-Occipit-atl-axl
0.125 0.875 0.000
M43.50 Other recurrent vertebral subluxation (Multiple sites in spine)
0.125 0.875 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.125 0.875 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.124 0.875 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.124 0.875 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.124 0.875 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.124 0.875 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.124 0.875 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.124 0.875 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.124 0.875 0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.124 0.876 0.000
M86.66 Other chronic osteomyelitis (Lower leg)
0.124 0.876 0.000
M89.98 Disorder of bone, unspecified (Other)
0.124 0.876 0.000
M22.1 Recurrent subluxation of patella
0.124 0.876 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.123 0.876 0.000
M40.4 Other lordosis
0.123 0.876 0.000
M40.3 Flatback syndrome
0.123 0.876 0.000
M40.1 Other secondary kyphosis
0.123 0.876 0.000
M40.0 Postural kyphosis
0.123 0.876 0.000
M93 Other osteochondropathies
0.123 0.877 0.000
M34.9 Systemic sclerosis, unspecified
0.123 0.877 0.000
M43.69 Torticollis-Site unspe
0.123 0.877 0.000
M43.68 Torticollis-Sacral/sacrococ
0.123 0.877 0.000
M43.67 Torticollis-Lumbosacral
0.123 0.877 0.000
M43.66 Torticollis-Lumbar
0.123 0.877 0.000
M43.65 Torticollis-Thoracolumbar
0.123 0.877 0.000
M43.64 Torticollis-Thoracic
0.123 0.877 0.000
M43.63 Torticollis-Cervicothoracic
0.123 0.877 0.000
M43.61 Torticollis-Occipit-atl-axl
0.123 0.877 0.000
M43.60 Torticollis-Mult site
0.123 0.877 0.000
M31.7 Microscopic polyangiitis
0.123 0.877 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.123 0.877 0.000
M31.2 Lethal midline granuloma
0.123 0.877 0.000
M31.1 Thrombotic microangiopathy
0.123 0.877 0.000
M83.3 Adult osteomalacia due to malnutrition
0.123 0.877 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.123 0.877 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.123 0.877 0.000
M86.69 Other chronic osteomyelitis (Site unspecified)
0.122 0.877 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.122 0.877 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.122 0.878 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.122 0.878 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.122 0.878 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.122 0.878 0.000
M31.6 Other giant cell arteritis
0.122 0.878 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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