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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2284175
log Bayes Factor = 75.4801
Chromosome 6   position 30,875,145  (GRCh37) Explore rs2284175 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.9 Without complications
0.000 0.002 0.998
L40.0 Psoriasis vulgaris
0.997 0.003 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.015 0.985
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.015 0.985
E10.4 With neurological complications
0.000 0.040 0.960
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.057 0.943
M07.39 Other psoriatic arthropathies (Site unspecified)
0.941 0.059 0.000
M07.3 Other psoriatic arthropathies
0.941 0.059 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.936 0.064 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.087 0.913
E10.3 With ophthalmic complications
0.000 0.097 0.903
E10.5 With peripheral circulatory complications
0.000 0.104 0.896
E16.2 Hypoglycaemia, unspecified
0.000 0.108 0.892
L40.8 Other psoriasis
0.891 0.109 0.000
E07 Other disorders of thyroid
0.000 0.121 0.879
E10.1 With ketoacidosis
0.000 0.128 0.872
L40.1 Generalised pustular psoriasis
0.854 0.146 0.000
E10.6 With other specified complications
0.000 0.167 0.833
E07.9 Disorder of thyroid, unspecified
0.000 0.171 0.829
M07.34 Other psoriatic arthropathies (Hand)
0.827 0.173 0.000
E10.2 With renal complications
0.000 0.187 0.813
E10.0 With coma
0.000 0.189 0.811
M07.36 Other psoriatic arthropathies (Lower leg)
0.803 0.197 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.199 0.801
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.782 0.218 0.000
E06 Thyroiditis
0.000 0.237 0.763
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.247 0.753
E50-E64 Other nutritional deficiencies
0.000 0.259 0.741
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.267 0.733
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.284 0.716
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.286 0.714
E12 Malnutrition-related diabetes mellitus
0.000 0.294 0.706
E15 Nondiabetic hypoglycaemic coma
0.000 0.324 0.676
M07.38 Other psoriatic arthropathies (Other)
0.674 0.325 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.674 0.325 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.674 0.325 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.674 0.325 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.674 0.325 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.346 0.654
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.346 0.654
E16.4 Abnormal secretion of gastrin
0.000 0.346 0.654
E16.3 Increased secretion of glucagon
0.000 0.346 0.654
E07.1 Dyshormogenetic goitre
0.000 0.370 0.630
E07.0 Hypersecretion of calcitonin
0.000 0.370 0.630
E03.8 Other specified hypothyroidism
0.000 0.397 0.602
E06.3 Autoimmune thyroiditis
0.000 0.412 0.588
E55 Vitamin D deficiency
0.000 0.415 0.585
E16.1 Other hypoglycaemia
0.000 0.439 0.561
E13 Other specified diabetes mellitus
0.000 0.440 0.560
E06.9 Thyroiditis, unspecified
0.000 0.447 0.553
E10.8 With unspecified complications
0.000 0.448 0.552
E06.5 Other chronic thyroiditis
0.000 0.453 0.547
E06.4 Drug-induced thyroiditis
0.000 0.453 0.547
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.453 0.547
E06.1 Subacute thyroiditis
0.000 0.453 0.547
E06.0 Acute thyroiditis
0.000 0.453 0.547
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.469 0.531
E63 Other nutritional deficiencies
0.000 0.469 0.531
E56 Other vitamin deficiencies
0.000 0.469 0.531
E51 Thiamine deficiency
0.000 0.469 0.531
E50 Vitamin A deficiency
0.000 0.469 0.531
E60 Dietary zinc deficiency
0.000 0.469 0.531
E59 Dietary selenium deficiency
0.000 0.469 0.531
E58 Dietary calcium deficiency
0.000 0.469 0.531
E54 Ascorbic acid deficiency
0.000 0.469 0.531
E52 Niacin deficiency [pellagra]
0.000 0.469 0.531
K90 Intestinal malabsorption
0.000 0.478 0.522
E53 Deficiency of other B group vitamins
0.000 0.478 0.522
E61 Deficiency of other nutrient elements
0.000 0.484 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E65-E68 Obesity and other hyperalimentation
0.000 0.488 0.512
E12.9 Without complications
0.000 0.494 0.506
E12.8 With unspecified complications
0.000 0.494 0.506
E12.7 With multiple complications
0.000 0.494 0.506
E12.6 With other specified complications
0.000 0.494 0.506
E12.5 With peripheral circulatory complications
0.000 0.494 0.506
E12.4 With neurological complications
0.000 0.494 0.506
E12.3 With ophthalmic complications
0.000 0.494 0.506
E12.2 With renal complications
0.000 0.494 0.506
E12.1 With ketoacidosis
0.000 0.494 0.506
E12.0 With coma
0.000 0.494 0.506
E40-E46 Malnutrition
0.001 0.510 0.489
E55.9 Vitamin D deficiency, unspecified
0.000 0.527 0.473
E14 Unspecified diabetes mellitus
0.000 0.528 0.472
E04 Other non-toxic goitre
0.000 0.555 0.445
E07.8 Other specified disorders of thyroid
0.000 0.556 0.444
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.562 0.438
E55.0 Rickets, active
0.000 0.580 0.419
E14.3 With ophthalmic complications
0.000 0.584 0.415
K90.9 Intestinal malabsorption, unspecified
0.000 0.587 0.413
M07 Psoriatic and enteropathic arthropathies
0.411 0.588 0.000
E13.8 With unspecified complications
0.000 0.598 0.401
E13.7 With multiple complications
0.000 0.598 0.401
E13.6 With other specified complications
0.000 0.598 0.401
E13.5 With peripheral circulatory complications
0.000 0.598 0.401
E13.4 With neurological complications
0.000 0.598 0.401
E13.3 With ophthalmic complications
0.000 0.598 0.401
E13.2 With renal complications
0.000 0.598 0.401
E13.1 With ketoacidosis
0.000 0.598 0.401
E13.0 With coma
0.000 0.598 0.401
E53.9 Vitamin B deficiency, unspecified
0.000 0.603 0.397
E50.9 Vitamin A deficiency, unspecified
0.000 0.619 0.381
E50.8 Other manifestations of vitamin A deficiency
0.000 0.619 0.381
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.619 0.381
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.619 0.381
E50.5 Vitamin A deficiency with night blindness
0.000 0.619 0.381
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.619 0.381
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.619 0.381
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.619 0.381
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.619 0.381
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.619 0.381
E51.9 Thiamine deficiency, unspecified
0.000 0.619 0.381
E51.8 Other manifestations of thiamine deficiency
0.000 0.619 0.381
E51.2 Wernicke's encephalopathy
0.000 0.619 0.381
E51.1 Beriberi
0.000 0.619 0.381
E56.9 Vitamin deficiency, unspecified
0.000 0.619 0.381
E56.8 Deficiency of other vitamins
0.000 0.619 0.381
E56.1 Deficiency of vitamin K
0.000 0.619 0.381
E56.0 Deficiency of vitamin E
0.000 0.619 0.381
E63.9 Nutritional deficiency, unspecified
0.000 0.619 0.381
E63.8 Other specified nutritional deficiencies
0.000 0.619 0.381
E63.1 Imbalance of constituents of food intake
0.000 0.619 0.381
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.619 0.381
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.619 0.381
E64.8 Sequelae of other nutritional deficiencies
0.000 0.619 0.381
E64.3 Sequelae of rickets
0.000 0.619 0.381
E64.2 Sequelae of vitamin C deficiency
0.000 0.619 0.381
E64.1 Sequelae of vitamin A deficiency
0.000 0.619 0.381
E64.0 Sequelae of protein-energy malnutrition
0.000 0.619 0.381
E61.2 Magnesium deficiency
0.000 0.623 0.377
K90.3 Pancreatic steatorrhoea
0.000 0.625 0.374
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.625 0.374
K90.1 Tropical sprue
0.000 0.625 0.374
E53.1 Pyridoxine deficiency
0.000 0.626 0.374
E53.0 Riboflavin deficiency
0.000 0.626 0.374
E61.9 Deficiency of nutrient element, unspecified
0.000 0.630 0.370
E61.8 Deficiency of other specified nutrient elements
0.000 0.630 0.370
E61.7 Deficiency of multiple nutrient elements
0.000 0.630 0.370
E61.6 Vanadium deficiency
0.000 0.630 0.370
E61.5 Molybdenum deficiency
0.000 0.630 0.370
E61.4 Chromium deficiency
0.000 0.630 0.370
E61.3 Manganese deficiency
0.000 0.630 0.370
E61.0 Copper deficiency
0.000 0.630 0.370
E67 Other hyperalimentation
0.000 0.633 0.367
E68 Sequelae of hyperalimentation
0.000 0.633 0.367
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.649 0.351
E45 Retarded development following protein-energy malnutrition
0.001 0.649 0.351
E43 Unspecified severe protein-energy malnutrition
0.001 0.649 0.351
E42 Marasmic kwashiorkor
0.001 0.649 0.351
E41 Nutritional marasmus
0.001 0.649 0.351
E40 Kwashiorkor
0.001 0.649 0.351
E04.9 Non-toxic goitre, unspecified
0.000 0.652 0.348
E61.1 Iron deficiency
0.000 0.653 0.346
E14.7 With multiple complications
0.000 0.662 0.338
E14.6 With other specified complications
0.000 0.662 0.338
E14.2 Withrenal complications
0.000 0.662 0.338
E14.0 With coma
0.000 0.662 0.338
E53.8 Deficiency of other specified B group vitamins
0.000 0.665 0.335
E14.1 With ketoacidosis
0.000 0.668 0.332
E14.8 With unspecified complications
0.000 0.677 0.323
E04.8 Other specified non-toxic goitre
0.000 0.681 0.319
E14.5 With peripheral circulatory complications
0.000 0.695 0.304
M07.6 Other enteropathic arthropathies
0.295 0.705 0.000
M07.5 Arthropathy in ulcerative colitis
0.295 0.705 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.295 0.705 0.000
M07.2 Psoriatic spondylitis
0.295 0.705 0.000
M07.1 Arthritis mutilans
0.295 0.705 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.295 0.705 0.000
E66 Obesity
0.000 0.707 0.293
E65 Localised adiposity
0.000 0.713 0.287
E14.4 With neurological complications
0.000 0.727 0.273
E04.0 Non-toxic diffuse goitre
0.000 0.728 0.272
E66.8 Other obesity
0.000 0.728 0.272
E20-E35 Disorders of other endocrine glands
0.000 0.734 0.266
E67.8 Other specified hyperalimentation
0.000 0.737 0.263
E67.3 Hypervitaminosis D
0.000 0.737 0.263
E67.2 Megavitamin-B6 syndrome
0.000 0.737 0.263
E67.1 Hypercarotenaemia
0.000 0.737 0.263
E67.0 Hypervitaminosis A
0.000 0.737 0.263
E13.9 Without complications
0.001 0.744 0.255
K90.8 Other intestinal malabsorption
0.001 0.745 0.254
E04.2 Non-toxic multinodular goitre
0.000 0.746 0.254
E44.1 Mild protein-energy malnutrition
0.001 0.748 0.251
E44.0 Moderate protein-energy malnutrition
0.001 0.748 0.251
E27 Other disorders of adrenal gland
0.000 0.761 0.239
E27.1 Primary adrenocortical insufficiency
0.000 0.765 0.235
L40-L45 Papulosquamous disorders
0.225 0.774 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.212 0.788 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.212 0.788 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.212 0.788 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.212 0.788 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.212 0.788 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.212 0.788 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.212 0.788 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.212 0.788 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.212 0.788 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.212 0.788 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.212 0.788 0.000
M07.18 Arthritis mutilans (Other)
0.212 0.788 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.212 0.788 0.000
M07.16 Arthritis mutilans (Lower leg)
0.212 0.788 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.212 0.788 0.000
M07.14 Arthritis mutilans (Hand)
0.212 0.788 0.000
M07.13 Arthritis mutilans (Forearm)
0.212 0.788 0.000
M07.12 Arthritis mutilans (Upper arm)
0.212 0.788 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.212 0.788 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.212 0.788 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.212 0.788 0.000
M07.28 Psoriatic spondylitis (Other)
0.212 0.788 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.212 0.788 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.212 0.788 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.212 0.788 0.000
M07.24 Psoriatic spondylitis (Hand)
0.212 0.788 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.212 0.788 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.212 0.788 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.212 0.788 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.212 0.788 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.212 0.788 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.212 0.788 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.212 0.788 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.212 0.788 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.212 0.788 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.212 0.788 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.212 0.788 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.212 0.788 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.212 0.788 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.212 0.788 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.212 0.788 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.212 0.788 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.212 0.788 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.212 0.788 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.212 0.788 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.212 0.788 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.212 0.788 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.212 0.788 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.212 0.788 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.212 0.788 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.212 0.788 0.000
M07.68 Other enteropathic arthropathies (Other)
0.212 0.788 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.212 0.788 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.212 0.788 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.212 0.788 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.212 0.788 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.212 0.788 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.212 0.788 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.212 0.788 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.212 0.788 0.000
E66.1 Drug-induced obesity
0.000 0.790 0.210
E04.1 Non-toxic single thyroid nodule
0.000 0.802 0.198
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.809 0.191
E32 Diseases of thymus
0.000 0.809 0.191
E31 Polyglandular dysfunction
0.000 0.809 0.191
E30 Disorders of puberty, not elsewhere classified
0.000 0.809 0.191
E25 Adrenogenital disorders
0.000 0.809 0.191
E34 Other endocrine disorders
0.000 0.812 0.188
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.818 0.182
E29 Testicular dysfunction
0.000 0.819 0.181
E20 Hypoparathyroidism
0.000 0.820 0.180
E27.8 Other specified disorders of adrenal gland
0.000 0.822 0.178
E27.5 Adrenomedullary hyperfunction
0.000 0.828 0.171
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.828 0.171
E27.0 Other adrenocortical overactivity
0.000 0.828 0.171
E22 Hyperfunction of pituitary gland
0.000 0.835 0.165
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.000 0.835 0.165
E26 Hyperaldosteronism
0.000 0.835 0.165
E24 Cushing's syndrome
0.000 0.837 0.163
L44 Other papulosquamous disorders
0.162 0.838 0.000
L41 Parapsoriasis
0.162 0.838 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.162 0.838 0.000
E27.2 Addisonian crisis
0.000 0.840 0.160
E28 Ovarian dysfunction
0.000 0.843 0.157
L42 Pityriasis rosea
0.157 0.843 0.000
E66.0 Obesity due to excess calories
0.000 0.844 0.155
E34.9 Endocrine disorder, unspecified
0.000 0.852 0.147
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.146 0.854 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.143 0.857 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.141 0.859 0.000
E34.0 Carcinoid syndrome
0.000 0.859 0.140
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.140 0.860 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.863 0.137
E25.8 Other adrenogenital disorders
0.000 0.863 0.137
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.863 0.137
E30.9 Disorder of puberty, unspecified
0.000 0.863 0.137
E30.8 Other disorders of puberty
0.000 0.863 0.137
E30.1 Precocious puberty
0.000 0.863 0.137
E30.0 Delayed puberty
0.000 0.863 0.137
E31.9 Polyglandular dysfunction, unspecified
0.000 0.863 0.137
E31.8 Other polyglandular dysfunction
0.000 0.863 0.137
E31.1 Polyglandular hyperfunction
0.000 0.863 0.137
E31.0 Autoimmune polyglandular failure
0.000 0.863 0.137
E32.9 Disease of thymus, unspecified
0.000 0.863 0.137
E32.8 Other diseases of thymus
0.000 0.863 0.137
E32.1 Abscess of thymus
0.000 0.863 0.137
E32.0 Persistent hyperplasia of thymus
0.000 0.863 0.137
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.863 0.137
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.863 0.137
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.863 0.137
E46 Unspecified protein-energy malnutrition
0.002 0.865 0.133
E34.5 Androgen resistance syndrome
0.000 0.865 0.135
E34.4 Constitutional tall stature
0.000 0.865 0.135
E34.3 Short stature, not elsewhere classified
0.000 0.865 0.135
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.865 0.135
E34.1 Other hypersecretion of intestinal hormones
0.000 0.865 0.135
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.134 0.866 0.000
T43.2 Other and unspecified antidepressants
0.132 0.868 0.000
E22.1 Hyperprolactinaemia
0.000 0.869 0.131
E29.9 Testicular dysfunction, unspecified
0.000 0.870 0.130
E29.8 Other testicular dysfunction
0.000 0.870 0.130
E29.0 Testicular hyperfunction
0.000 0.870 0.130
E20.8 Other hypoparathyroidism
0.000 0.871 0.129
E20.1 Pseudohypoparathyroidism
0.000 0.871 0.129
E20.0 Idiopathic hypoparathyroidism
0.000 0.871 0.129
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.125 0.875 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.124 0.876 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.123 0.877 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.122 0.878 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.879 0.121
E29.1 Testicular hypofunction
0.000 0.881 0.119
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.119 0.881 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.881 0.119
E22.8 Other hyperfunction of pituitary gland
0.000 0.881 0.119
E20.9 Hypoparathyroidism, unspecified
0.000 0.881 0.118
E24.2 Drug-induced Cushing's syndrome
0.000 0.882 0.118
E26.9 Hyperaldosteronism, unspecified
0.000 0.882 0.118
E26.8 Other hyperaldosteronism
0.000 0.882 0.118
E26.1 Secondary hyperaldosteronism
0.000 0.882 0.118
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.882 0.118
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.118 0.882 0.000
E24.8 Other Cushing's syndrome
0.000 0.883 0.117
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.883 0.117
E24.3 Ectopic ACTH syndrome
0.000 0.883 0.117
E24.1 Nelson's syndrome
0.000 0.883 0.117
L41.9 Parapsoriasis, unspecified
0.116 0.884 0.000
L41.8 Other parapsoriasis
0.116 0.884 0.000
L41.5 Retiform parapsoriasis
0.116 0.884 0.000
L41.4 Large plaque parapsoriasis
0.116 0.884 0.000
L41.3 Small plaque parapsoriasis
0.116 0.884 0.000
L41.2 Lymphomatoid papulosis
0.116 0.884 0.000
L41.1 Pityriasis lichenoides chronica
0.116 0.884 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.116 0.884 0.000
L44.9 Papulosquamous disorder, unspecified
0.116 0.884 0.000
L44.8 Other specified papulosquamous disorders
0.116 0.884 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.116 0.884 0.000
L44.3 Lichen ruber moniliformis
0.116 0.884 0.000
L44.2 Lichen striatus
0.116 0.884 0.000
L44.1 Lichen nitidus
0.116 0.884 0.000
L44.0 Pityriasis rubra pilaris
0.116 0.884 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.885 0.115
T43.6 Psychostimulants with abuse potential
0.115 0.885 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.887 0.113
E28.8 Other ovarian dysfunction
0.000 0.887 0.113
E28.1 Androgen excess
0.000 0.887 0.113
E28.0 Oestrogen excess
0.000 0.887 0.113
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.113 0.887 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.112 0.888 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.890 0.110
E28.3 Primary ovarian failure
0.000 0.890 0.109
T47.1 Other antacids and anti-gastric-secretion drugs
0.109 0.891 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.109 0.891 0.000
T36 Poisoning by systemic antibiotics
0.108 0.892 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.107 0.893 0.000
E27.9 Disorder of adrenal gland, unspecified
0.001 0.894 0.106
E24.0 Pituitary-dependent Cushing's disease
0.000 0.894 0.105
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.105 0.895 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.105 0.895 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.105 0.895 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.105 0.895 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.105 0.895 0.000
T44.0 Anticholinesterase agents
0.105 0.895 0.000
E34.8 Other specified endocrine disorders
0.000 0.895 0.104
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.104 0.896 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.104 0.896 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.897 0.103
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.103 0.897 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.103 0.897 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.103 0.897 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.103 0.897 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.102 0.898 0.000
T43.9 Psychotropic drug, unspecified
0.102 0.898 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.102 0.898 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.102 0.898 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.099 0.901 0.000
T47.4 Other laxatives
0.098 0.902 0.000
E26.0 Primary hyperaldosteronism
0.000 0.908 0.092
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.090 0.910 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.090 0.910 0.000
T47.7 Emetics
0.090 0.910 0.000
T47.6 Antidiarrhoeal drugs
0.090 0.910 0.000
T47.5 Digestants
0.090 0.910 0.000
T47.3 Saline and osmotic laxatives
0.090 0.910 0.000
T47.2 Stimulant laxatives
0.090 0.910 0.000
T47.0 Histamine H(2)-receptor antagonists
0.090 0.910 0.000
T50.8 Diagnostic agents
0.088 0.912 0.000
T50.7 Analeptics and opioid receptor antagonists
0.088 0.912 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.088 0.912 0.000
T50.5 Appetite depressants
0.088 0.912 0.000
T50.4 Drugs affecting uric acid metabolism
0.088 0.912 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.088 0.912 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.088 0.912 0.000
T50.1 Loop [high-ceiling] diuretics
0.088 0.912 0.000
T50.0 Mineralocorticoids and their antagonists
0.088 0.912 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.088 0.912 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.913 0.087
E23.1 Drug-induced hypopituitarism
0.000 0.913 0.087
T46.4 Angiotensin-converting-enzyme inhibitors
0.086 0.914 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.086 0.914 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.086 0.914 0.000
T42.3 Barbiturates
0.086 0.914 0.000
T42.2 Succinimides and oxazolidinediones
0.086 0.914 0.000
E23.0 Hypopituitarism
0.000 0.915 0.085
E28.2 Polycystic ovarian syndrome
0.000 0.915 0.085
T45.0 Antiallergic and antiemetic drugs
0.085 0.915 0.000
T38.1 Thyroid hormones and substitutes
0.084 0.915 0.000
T36.0 Penicillins
0.083 0.916 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.083 0.917 0.000
T42.0 Hydantoin derivatives
0.083 0.917 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.917 0.083
E21.2 Other hyperparathyroidism
0.000 0.917 0.083
E21.0 Primary hyperparathyroidism
0.000 0.918 0.082
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.918 0.081
E23.2 Diabetes insipidus
0.000 0.918 0.081
T42.1 Iminostilbenes
0.081 0.918 0.000
T38.9 Other and unspecified hormone antagonists
0.081 0.919 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.081 0.919 0.000
T38.7 Androgens and anabolic congeners
0.081 0.919 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.081 0.919 0.000
T38.5 Other oestrogens and progestogens
0.081 0.919 0.000
T38.4 Oral contraceptives
0.081 0.919 0.000
T38.2 Antithyroid drugs
0.081 0.919 0.000
T38.0 Glucocorticoids and synthetic analogues
0.081 0.919 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.081 0.919 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.080 0.920 0.000
L43 Lichen planus
0.079 0.920 0.001
T36.9 Systemic antibiotic, unspecified
0.078 0.922 0.000
T36.8 Other systemic antibiotics
0.078 0.922 0.000
T36.7 Antifungal antibiotics, systemically used
0.078 0.922 0.000
T36.6 Rifamycins
0.078 0.922 0.000
T36.5 Aminoglycosides
0.078 0.922 0.000
T36.4 Tetracyclines
0.078 0.922 0.000
T36.3 Macrolides
0.078 0.922 0.000
T36.2 Chloramphenicol group
0.078 0.922 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.078 0.922 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.077 0.923 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.077 0.923 0.000
T46.7 Peripheral vasodilators
0.077 0.923 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.077 0.923 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.077 0.923 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.077 0.923 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.076 0.924 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.925 0.075
T45.9 Primarily systemic and haematological agent, unspecified
0.074 0.925 0.000
T45.8 Other primarily systemic and haematological agents
0.074 0.925 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.074 0.925 0.000
T45.6 Fibrinolysis-affecting drugs
0.074 0.925 0.000
T45.4 Iron and its compounds
0.074 0.925 0.000
T45.3 Enzymes, not elsewhere classified
0.074 0.925 0.000
T45.2 Vitamins, not elsewhere classified
0.074 0.925 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.074 0.926 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.074 0.926 0.000
T37.5 Antiviral drugs
0.074 0.926 0.000
T37.4 Anthelminthics
0.074 0.926 0.000
T37.3 Other antiprotozoal drugs
0.074 0.926 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.074 0.926 0.000
T37.1 Antimycobacterial drugs
0.074 0.926 0.000
T37.0 Sulphonamides
0.074 0.926 0.000
T41.5 Therapeutic gases
0.074 0.926 0.000
T41.4 Anaesthetic, unspecified
0.074 0.926 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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