TreeWAS – Variant ID: rs2284386

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C44 Other malignant neoplasms of skin	1.000	0.000	0.000
C43 Malignant melanoma of skin	1.000	0.000	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.999	0.001	0.000
C44.4 Skin of scalp and neck	0.999	0.001	0.000
C44.6 Skin of upper limb, including shoulder	0.998	0.002	0.000
C44.5 Skin of trunk	0.994	0.006	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.992	0.008	0.000
C43.5 Malignant melanoma of trunk	0.986	0.014	0.000
C43.4 Malignant melanoma of scalp and neck	0.962	0.038	0.000
C44.3 Skin of other and unspecified parts of face	0.954	0.046	0.000
C44.0 Skin of lip	0.905	0.095	0.000
C44.2 Skin of ear and external auricular canal	0.875	0.125	0.000
C43.9 Malignant melanoma of skin, unspecified	0.846	0.154	0.000
C44.7 Skin of lower limb, including hip	0.812	0.188	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.804	0.196	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.780	0.220	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.751	0.249	0.000
C44.8 Overlapping lesion of skin	0.717	0.283	0.000
C43.8 Overlapping malignant melanoma of skin	0.717	0.283	0.000
C43.0 Malignant melanoma of lip	0.717	0.283	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.716	0.284	0.000
C44.1 Skin of eyelid, including canthus	0.607	0.393	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.563	0.437	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.450	0.550	0.000
E11.9 Without complications	0.000	0.571	0.429
E11 Non-insulin-dependent diabetes mellitus	0.000	0.581	0.419
E11.5 With peripheral circulatory complications	0.000	0.585	0.415
E11.3 With ophthalmic complications	0.000	0.615	0.385
E11.1 With ketoacidosis	0.000	0.661	0.339
C43.7 Malignant melanoma of lower limb, including hip	0.326	0.674	0.000
E11.8 With unspecified complications	0.000	0.695	0.305
E11.7 With multiple complications	0.000	0.699	0.301
E11.6 With other specified complications	0.000	0.705	0.294
L57.0 Actinic keratosis	0.293	0.707	0.000
E11.4 With neurological complications	0.000	0.712	0.288
E11.2 With renal complications	0.000	0.723	0.277
E11.0 With coma	0.000	0.755	0.244
L57 Skin changes due to chronic exposure to nonionising radiation	0.144	0.856	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.118	0.882	0.000
L57.5 Actinic granuloma	0.103	0.896	0.000
L57.3 Poikiloderma of Civatte	0.103	0.896	0.000
L57.2 Cutis rhomboidalis nuchae	0.103	0.896	0.000
L57.1 Actinic reticuloid	0.103	0.896	0.000
Z35.5 Supervision of elderly primigravida	0.098	0.902	0.000
L57.4 Cutis laxa senilis	0.093	0.907	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.091	0.909	0.000
Z35 Supervision of high-risk pregnancy	0.083	0.917	0.000
R32 Unspecified urinary incontinence	0.000	0.924	0.076
Z35.0 Supervision of pregnancy with history of infertility	0.075	0.925	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.071	0.929	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.070	0.930	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.070	0.930	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.066	0.934	0.000
L55 Sunburn	0.065	0.935	0.000
L58 Radiodermatitis	0.065	0.935	0.000
Z35.8 Supervision of other high-risk pregnancies	0.063	0.937	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.063	0.937	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.060	0.939	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.060	0.940	0.000
Z35.6 Supervision of very young primigravida	0.060	0.940	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.060	0.940	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.060	0.940	0.000
L85.9 Epidermal thickening, unspecified	0.059	0.941	0.000
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified	0.057	0.943	0.000
L85 Other epidermal thickening	0.055	0.945	0.000
L85.8 Other specified epidermal thickening	0.053	0.947	0.000
L56.4 Polymorphous light eruption	0.051	0.949	0.000
L56.3 Solar urticaria	0.051	0.949	0.000
L56.2 Photocontact dermatitis [berloque dermatitis]	0.051	0.949	0.000
L56.1 Drug photoallergic response	0.051	0.949	0.000
L56.0 Drug phototoxic response	0.051	0.949	0.000
L59.0 Erythema ab igne [dermatitis ab igne]	0.050	0.949	0.000
E10-E14 Diabetes mellitus	0.000	0.950	0.050
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation	0.049	0.951	0.000
L55.9 Sunburn, unspecified	0.047	0.953	0.000
L55.8 Other sunburn	0.047	0.953	0.000
L55.2 Sunburn of third degree	0.047	0.953	0.000
L55.1 Sunburn of second degree	0.047	0.953	0.000
L55.0 Sunburn of first degree	0.047	0.953	0.000
L58.1 Chronic radiodermatitis	0.047	0.953	0.000
L58.0 Acute radiodermatitis	0.047	0.953	0.000
L58.9 Radiodermatitis, unspecified	0.047	0.953	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.045	0.955	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.043	0.957	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.043	0.957	0.000
L85.3 Xerosis cutis	0.040	0.960	0.000
L85.2 Keratosis punctata (palmaris et plantaris)	0.040	0.960	0.000
L85.0 Acquired ichthyosis	0.040	0.960	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.039	0.961	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.037	0.963	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.964	0.036
L80-L99 Other disorders of the skin and subcutaneous tissue	0.036	0.964	0.000
L82 Seborrhoeic keratosis	0.034	0.966	0.000
E13 Other specified diabetes mellitus	0.000	0.967	0.032
L84 Corns and callosities	0.032	0.968	0.000
E14 Unspecified diabetes mellitus	0.000	0.969	0.031
L98.4 Chronic ulcer of skin, not elsewhere classified	0.031	0.969	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.031	0.969	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.031	0.969	0.000
L93 Lupus erythematosus	0.030	0.969	0.000
E14.3 With ophthalmic complications	0.000	0.970	0.030
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.030	0.970	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.029	0.971	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.028	0.972	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.028	0.972	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.973	0.027
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.027	0.973	0.000
L93.0 Discoid lupus erythematosus	0.027	0.973	0.000
E12.9 Without complications	0.000	0.974	0.026
E12.8 With unspecified complications	0.000	0.974	0.026
E12.7 With multiple complications	0.000	0.974	0.026
E12.6 With other specified complications	0.000	0.974	0.026
E12.5 With peripheral circulatory complications	0.000	0.974	0.026
E12.4 With neurological complications	0.000	0.974	0.026
E12.3 With ophthalmic complications	0.000	0.974	0.026
E12.2 With renal complications	0.000	0.974	0.026
E12.1 With ketoacidosis	0.000	0.974	0.026
E12.0 With coma	0.000	0.974	0.026
L87 Transepidermal elimination disorders	0.026	0.974	0.000
L86 Keratoderma in diseases classified elsewhere	0.026	0.974	0.000
L98.1 Factitial dermatitis	0.026	0.974	0.000
L90 Atrophic disorders of skin	0.025	0.975	0.000
L94 Other localised connective tissue disorders	0.025	0.975	0.000
L83 Acanthosis nigricans	0.025	0.975	0.000
E14.2 Withrenal complications	0.000	0.976	0.024
E13.8 With unspecified complications	0.000	0.976	0.023
E13.7 With multiple complications	0.000	0.976	0.023
E13.6 With other specified complications	0.000	0.976	0.023
E13.5 With peripheral circulatory complications	0.000	0.976	0.023
E13.4 With neurological complications	0.000	0.976	0.023
E13.3 With ophthalmic complications	0.000	0.976	0.023
E13.2 With renal complications	0.000	0.976	0.023
E13.1 With ketoacidosis	0.000	0.976	0.023
E13.0 With coma	0.000	0.976	0.023
L95.8 Other vasculitis limited to skin	0.023	0.977	0.000
E14.4 With neurological complications	0.000	0.977	0.023
E14.7 With multiple complications	0.000	0.977	0.023
L98.7 Excessive and redundant skin and subcutaneous tissue	0.023	0.977	0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.023	0.977	0.000
L98.3 Eosinophilic cellulitis [Wells]	0.023	0.977	0.000
L10-L14 Bullous disorders	0.023	0.977	0.000
L20-L30 Dermatitis and eczema	0.023	0.977	0.000
E14.8 With unspecified complications	0.000	0.977	0.023
L95.9 Vasculitis limited to skin, unspecified	0.023	0.977	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.022	0.978	0.000
L93.2 Other local lupus erythematosus	0.022	0.978	0.000
L93.1 Subacute cutaneous lupus erythematosus	0.022	0.978	0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.022	0.978	0.000
L99.8 Other specified disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.022	0.978	0.000
L30.8 Other specified dermatitis	0.022	0.978	0.000
E14.6 With other specified complications	0.000	0.978	0.021
L88 Pyoderma gangrenosum	0.021	0.978	0.000
L95.1 Erythema elevatum diutinum	0.021	0.979	0.000
L95.0 Livedoid vasculitis	0.021	0.979	0.000
L94.2 Calcinosis cutis	0.021	0.979	0.000
L90.5 Scar conditions and fibrosis of skin	0.021	0.979	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.021	0.979	0.000
E14.0 With coma	0.000	0.979	0.020
L30 Other dermatitis	0.021	0.979	0.000
M23.3 Other meniscus derangements	0.020	0.980	0.000
L94.8 Other specified localised connective tissue disorders	0.020	0.980	0.000
L99.0 Amyloidosis of skin	0.020	0.980	0.000
M23 Internal derangement of knee	0.020	0.980	0.000
E13.9 Without complications	0.000	0.980	0.020
L29 Pruritus	0.020	0.980	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.020	0.980	0.000
L90.9 Atrophic disorder of skin, unspecified	0.020	0.980	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.019	0.981	0.000
E14.1 With ketoacidosis	0.000	0.981	0.019
E14.5 With peripheral circulatory complications	0.000	0.981	0.019
L87.9 Transepidermal elimination disorder, unspecified	0.019	0.981	0.000
L87.8 Other transepidermal elimination disorders	0.019	0.981	0.000
L87.2 Elastosis perforans serpiginosa	0.019	0.981	0.000
L87.1 Reactive perforating collagenosis	0.019	0.981	0.000
L87.0 Keratosis follicularis et parafollicularis in cutem penetrans [Kyrle]	0.019	0.981	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.000	0.981	0.019
T85 Complications of other internal prosthetic devices, implants and grafts	0.000	0.981	0.019
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.019	0.981	0.000
L90.6 Striae atrophicae	0.018	0.981	0.000
L90.4 Acrodermatitis chronica atrophicans	0.018	0.981	0.000
L90.3 Atrophoderma of Pasini and Pierini	0.018	0.981	0.000
L90.2 Anetoderma of Jadassohn-Pellizzari	0.018	0.981	0.000
L90.1 Anetoderma of Schweninger-Buzzi	0.018	0.981	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.018	0.982	0.000
L94.6 Ainhum	0.018	0.982	0.000
L94.5 Poikiloderma vasculare atrophicans	0.018	0.982	0.000
L94.4 Gottron's papules	0.018	0.982	0.000
L94.3 Sclerodactyly	0.018	0.982	0.000
L94.1 Linear scleroderma	0.018	0.982	0.000
L11 Other acantholytic disorders	0.018	0.982	0.000
C61 Malignant neoplasm of prostate	0.018	0.982	0.000
L29.8 Other pruritus	0.018	0.982	0.000
C71 Malignant neoplasm of brain	0.018	0.982	0.000
L10 Pemphigus	0.018	0.982	0.000
L90.8 Other atrophic disorders of skin	0.018	0.982	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.018	0.982	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.982	0.018
L92.0 Granuloma annulare	0.018	0.982	0.000
L98.5 Mucinosis of skin	0.017	0.983	0.000
L98.0 Pyogenic granuloma	0.017	0.983	0.000
T85.2 Mechanical complication of intraocular lens	0.000	0.983	0.017
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.983	0.017
L21 Seborrhoeic dermatitis	0.017	0.983	0.000
L29.2 Pruritus vulvae	0.017	0.983	0.000
L14 Bullous disorders in diseases classified elsewhere	0.016	0.983	0.000
C60-C63 Malignant neoplasms of male genital organs	0.017	0.983	0.000
L24 Irritant contact dermatitis	0.016	0.983	0.000
L26 Exfoliative dermatitis	0.016	0.983	0.000
L22 Diaper [napkin] dermatitis	0.016	0.983	0.000
C69 Malignant neoplasm of eye and adnexa	0.017	0.983	0.000
C71.9 Brain, unspecified	0.016	0.984	0.000
L29.0 Pruritus ani	0.016	0.984	0.000
L81 Other disorders of pigmentation	0.016	0.984	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.016	0.984	0.000
L30.3 Infective dermatitis	0.016	0.984	0.000
Chapter II Neoplasms	0.016	0.984	0.000
C71.0 Cerebrum, except lobes and ventricles	0.016	0.984	0.000
D07.5 Prostate	0.016	0.984	0.000
C71.4 Occipital lobe	0.016	0.984	0.000
L13 Other bullous disorders	0.015	0.984	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.016	0.984	0.000
L20 Atopic dermatitis	0.015	0.984	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.015	0.985	0.000
M23.5 Chronic instability of knee	0.015	0.985	0.000
M23.0 Cystic meniscus	0.015	0.985	0.000
M23.1 Discoid meniscus (congenital)	0.015	0.985	0.000
L30.4 Erythema intertrigo	0.015	0.985	0.000
L94.0 Localised scleroderma [morphea]	0.015	0.985	0.000
L30.5 Pityriasis alba	0.015	0.985	0.000
L30.2 Cutaneous autosensitisation	0.015	0.985	0.000
L30.0 Nummular dermatitis	0.015	0.985	0.000
L11.0 Acquired keratosis follicularis	0.015	0.985	0.000
M23.9 Internal derangement of knee, unspecified	0.015	0.985	0.000
J91 Pleural effusion in conditions classified elsewhere	0.000	0.985	0.015
J94 Other pleural conditions	0.000	0.985	0.015
M23.37 Other meniscus derangements-Capsular lig	0.015	0.985	0.000
C71.1 Frontal lobe	0.015	0.985	0.000
J90-J94 Other diseases of pleura	0.000	0.985	0.015
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.014	0.985	0.000
L29.1 Pruritus scroti	0.014	0.985	0.000
L12 Pemphigoid	0.014	0.985	0.000
L29.3 Anogenital pruritus, unspecified	0.014	0.986	0.000
L28 Lichen simplex chronicus and prurigo	0.014	0.986	0.000
C71.3 Parietal lobe	0.014	0.986	0.000
L30.1 Dyshidrosis [pompholyx]	0.014	0.986	0.000
C69.0 Conjunctiva	0.014	0.986	0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.014	0.986	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.014	0.986	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.986	0.014
C69.9 Eye, unspecified	0.014	0.986	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.014	0.986	0.000
L10.0 Pemphigus vulgaris	0.014	0.986	0.000
L94.9 Localised connective tissue disorder, unspecified	0.014	0.986	0.000
L25 Unspecified contact dermatitis	0.014	0.986	0.000
L50-L54 Urticaria and erythema	0.014	0.986	0.000
D00-D09 In situ neoplasms	0.014	0.986	0.000
L27 Dermatitis due to substances taken internally	0.014	0.986	0.000
L10.9 Pemphigus, unspecified	0.013	0.986	0.000
L81.8 Other specified disorders of pigmentation	0.013	0.987	0.000
L11.9 Acantholytic disorder, unspecified	0.013	0.987	0.000
L11.8 Other specified acantholytic disorders	0.013	0.987	0.000
L11.1 Transient acantholytic dermatosis [Grover]	0.013	0.987	0.000
J90 Pleural effusion, not elsewhere classified	0.000	0.987	0.013
C71.7 Brain stem	0.013	0.987	0.000
C71.6 Cerebellum	0.013	0.987	0.000
C71.5 Cerebral ventricle	0.013	0.987	0.000
J94.2 Haemothorax	0.000	0.987	0.013
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.013	0.987	0.000
J92 Pleural plaque	0.000	0.987	0.013
L23 Allergic contact dermatitis	0.013	0.987	0.000
C69.2 Retina	0.013	0.987	0.000
L81.2 Freckles	0.013	0.987	0.000
J94.1 Fibrothorax	0.000	0.987	0.013
L10.8 Other pemphigus	0.013	0.987	0.000
L10.5 Drug-induced pemphigus	0.013	0.987	0.000
L10.4 Pemphigus erythematosus	0.013	0.987	0.000
L10.3 Brazilian pemphigus [fogo selvagem]	0.013	0.987	0.000
L10.2 Pemphigus foliaceus	0.013	0.987	0.000
L10.1 Pemphigus vegetans	0.013	0.987	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.013	0.987	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.013	0.987	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.013	0.987	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.013	0.987	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.987	0.013
L21.9 Seborrhoeic dermatitis, unspecified	0.013	0.987	0.000
C69.4 Ciliary body	0.013	0.987	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.013	0.987	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.013	0.987	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.013	0.987	0.000
D03 Melanoma in situ	0.012	0.988	0.000
L21.8 Other seborrhoeic dermatitis	0.012	0.988	0.000
L21.1 Seborrhoeic infantile dermatitis	0.012	0.988	0.000
L21.0 Seborrhoea capitis	0.012	0.988	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.012	0.988	0.000
C70 Malignant neoplasm of meninges	0.012	0.988	0.000
C69.3 Choroid	0.012	0.988	0.000
J94.8 Other specified pleural conditions	0.000	0.988	0.012
D07.0 Endometrium	0.012	0.988	0.000
L27.2 Dermatitis due to ingested food	0.012	0.988	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.012	0.988	0.000
L24.9 Irritant contact dermatitis, unspecified cause	0.012	0.988	0.000
L24.8 Irritant contact dermatitis due to other agents	0.012	0.988	0.000
L24.7 Irritant contact dermatitis due to plants, except food	0.012	0.988	0.000
L24.6 Irritant contact dermatitis due to food in contact with the skin	0.012	0.988	0.000
L24.5 Irritant contact dermatitis due to other chemical products	0.012	0.988	0.000
L24.4 Irritant contact dermatitis due to drugs in contact with the skin	0.012	0.988	0.000
L24.3 Irritant contact dermatitis due to cosmetics	0.012	0.988	0.000
L24.2 Irritant contact dermatitis due to solvents	0.012	0.988	0.000
L24.1 Irritant contact dermatitis due to oils and greases	0.012	0.988	0.000
L24.0 Irritant contact dermatitis due to detergents	0.012	0.988	0.000
L90.0 Lichen sclerosus et atrophicus	0.012	0.988	0.000
C69.8 Overlapping lesion of eye and adnexa	0.012	0.988	0.000
C69.5 Lachrymal gland and duct	0.012	0.988	0.000
C69.1 Cornea	0.012	0.988	0.000
C71.2 Temporal lobe	0.012	0.988	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.000	0.988	0.012
D03.6 Melanoma in situ of upper limb, including shoulder	0.012	0.988	0.000
L81.7 Pigmented purpuric dermatosis	0.012	0.988	0.000
L81.6 Other disorders of diminished melanin formation	0.012	0.988	0.000
L81.5 Leukoderma, not elsewhere classified	0.012	0.988	0.000
L81.3 Cafe au lait spots	0.012	0.988	0.000
L81.1 Chloasma	0.012	0.988	0.000
H18 Other disorders of cornea	0.012	0.988	0.000
L81.0 Postinflammatory hyperpigmentation	0.012	0.988	0.000
C60 Malignant neoplasm of penis	0.012	0.988	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.012	0.988	0.000
H18.8 Other specified disorders of cornea	0.012	0.988	0.000
D03.5 Melanoma in situ of trunk	0.012	0.988	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.011	0.988	0.000
C12 Malignant neoplasm of pyriform sinus	0.011	0.988	0.000
C62 Malignant neoplasm of testis	0.011	0.988	0.000
H16.0 Corneal ulcer	0.011	0.989	0.000
L13.9 Bullous disorder, unspecified	0.011	0.989	0.000
L13.8 Other specified bullous disorders	0.011	0.989	0.000
L13.1 Subcorneal pustular dermatitis	0.011	0.989	0.000
L20.8 Other atopic dermatitis	0.011	0.989	0.000
L20.0 Besnier's prurigo	0.011	0.989	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.011	0.989	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.011	0.989	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.011	0.989	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.011	0.989	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.011	0.989	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.011	0.989	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.011	0.989	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.011	0.989	0.000
M23.07 Cystic meniscus-Capsular lig	0.011	0.989	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.011	0.989	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.011	0.989	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.011	0.989	0.000
M23.00 Cystic meniscus (Multiple sites)	0.011	0.989	0.000
D04 Carcinoma in situ of skin	0.011	0.989	0.000
C06.0 Cheek mucosa	0.011	0.989	0.000
H18.2 Other corneal oedema	0.011	0.989	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.011	0.989	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.011	0.989	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.011	0.989	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.011	0.989	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.011	0.989	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.011	0.989	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.011	0.989	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.011	0.989	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.011	0.989	0.000
L12.9 Pemphigoid, unspecified	0.011	0.989	0.000
H18.4 Corneal degeneration	0.011	0.989	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.011	0.989	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.011	0.989	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.011	0.989	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.011	0.989	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.011	0.989	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.011	0.989	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.011	0.989	0.000
C69.6 Orbit	0.011	0.989	0.000
J94.9 Pleural condition, unspecified	0.000	0.989	0.011
J94.0 Chylous effusion	0.000	0.989	0.011
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.011	0.989	0.000
C71.8 Overlapping lesion of brain	0.011	0.989	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.011	0.989	0.000
L28.2 Other prurigo	0.011	0.989	0.000
L12.8 Other pemphigoid	0.010	0.989	0.000
L12.3 Acquired epidermolysis bullosa	0.010	0.989	0.000
L12.2 Chronic bullous disease of childhood	0.010	0.989	0.000
D07.4 Penis	0.011	0.989	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.000	0.989	0.010
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.000	0.989	0.010
H18.1 Bullous keratopathy	0.010	0.990	0.000
D07.6 Other and unspecified male genital organs	0.010	0.990	0.000
D07.3 Other and unspecified female genital organs	0.010	0.990	0.000
G93.9 Disorder of brain, unspecified	0.010	0.990	0.000
D04.5 Skin of trunk	0.010	0.990	0.000
D07.2 Vagina	0.010	0.990	0.000
C06.2 Retromolar area	0.010	0.990	0.000
L13.0 Dermatitis herpetiformis	0.010	0.990	0.000
D03.8 Melanoma in situ of other sites	0.010	0.990	0.000
C06.9 Mouth, unspecified	0.010	0.990	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.010	0.990	0.000
C13 Malignant neoplasm of hypopharynx	0.010	0.990	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.010	0.990	0.000
L20.9 Atopic dermatitis, unspecified	0.010	0.990	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.010	0.990	0.000
C11 Malignant neoplasm of nasopharynx	0.010	0.990	0.000
H16 Keratitis	0.010	0.990	0.000
L12.1 Cicatricial pemphigoid	0.010	0.990	0.000
L25.8 Unspecified contact dermatitis due to other agents	0.010	0.990	0.000
L25.5 Unspecified contact dermatitis due to plants, except food	0.010	0.990	0.000
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.010	0.990	0.000
L25.3 Unspecified contact dermatitis due to other chemical products	0.010	0.990	0.000
L25.2 Unspecified contact dermatitis due to dyes	0.010	0.990	0.000
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin	0.010	0.990	0.000
L25.0 Unspecified contact dermatitis due to cosmetics	0.010	0.990	0.000
L51 Erythema multiforme	0.010	0.990	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.010	0.990	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.010	0.990	0.000
L54 Erythema in diseases classified elsewhere	0.010	0.990	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.010	0.990	0.000
L27.8 Dermatitis due to other substances taken internally	0.010	0.990	0.000
C72.0 Spinal cord	0.010	0.990	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.010	0.990	0.000
I26 Pulmonary embolism	0.000	0.990	0.010
L80 Vitiligo	0.008	0.990	0.002
C63.2 Scrotum	0.010	0.990	0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.010	0.990	0.000
C03 Malignant neoplasm of gum	0.010	0.990	0.000
C72.9 Central nervous system, unspecified	0.010	0.990	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.010	0.990	0.000
C72.5 Other and unspecified cranial nerves	0.010	0.990	0.000
C72.4 Acoustic nerve	0.010	0.990	0.000
C72.3 Optic nerve	0.010	0.990	0.000
C72.2 Olfactory nerve	0.010	0.990	0.000
C72.1 Cauda equina	0.010	0.990	0.000
L23.8 Allergic contact dermatitis due to other agents	0.010	0.990	0.000
L23.7 Allergic contact dermatitis due to plants, except food	0.010	0.990	0.000
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.010	0.990	0.000
L23.4 Allergic contact dermatitis due to dyes	0.010	0.990	0.000
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.010	0.990	0.000
L23.2 Allergic contact dermatitis due to cosmetics	0.010	0.990	0.000
L23.0 Allergic contact dermatitis due to metals	0.010	0.990	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.010	0.990	0.000
D04.6 Skin of upper limb, including shoulder	0.010	0.990	0.000
C10 Malignant neoplasm of oropharynx	0.010	0.990	0.000
C64-C68 Malignant neoplasms of urinary tract	0.010	0.990	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.010	0.990	0.000
C62.1 Descended testis	0.010	0.990	0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)	0.009	0.990	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.009	0.990	0.000
G60.0 Hereditary motor and sensory neuropathy	0.000	0.990	0.010
L28.1 Prurigo nodularis	0.009	0.990	0.000
D03.0 Melanoma in situ of lip	0.009	0.991	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.009	0.991	0.000
C04 Malignant neoplasm of floor of mouth	0.009	0.991	0.000
L28.0 Lichen simplex chronicus	0.009	0.991	0.000
C41.1 Mandible	0.009	0.991	0.000
C63.9 Male genital organ, unspecified	0.009	0.991	0.000
C63.8 Overlapping lesion of male genital organs	0.009	0.991	0.000
C63.7 Other specified male genital organs	0.009	0.991	0.000
C63.1 Spermatic cord	0.009	0.991	0.000
C63.0 Epididymis	0.009	0.991	0.000
L52 Erythema nodosum	0.009	0.991	0.000
U80.1 Methicillin resistant agent	0.000	0.991	0.009
M23.8 Other internal derangements of knee	0.009	0.991	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.991	0.009
D04.7 Skin of lower limb, including hip	0.009	0.991	0.000
C66 Malignant neoplasm of ureter	0.009	0.991	0.000
J93 Pneumothorax	0.000	0.991	0.009
D03.9 Melanoma in situ, unspecified	0.009	0.991	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.009	0.991	0.000
C06.1 Vestibule of mouth	0.009	0.991	0.000
C70.9 Meninges, unspecified	0.009	0.991	0.000
C70.1 Spinal meninges	0.009	0.991	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.009	0.991	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.009	0.991	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.009	0.991	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.009	0.991	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.009	0.991	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.009	0.991	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.009	0.991	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.009	0.991	0.000
D05 Carcinoma in situ of breast	0.009	0.991	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.009	0.991	0.000
C00 Malignant neoplasm of lip	0.009	0.991	0.000
C60.0 Prepuce	0.009	0.991	0.000
L50 Urticaria	0.009	0.991	0.000
L91 Hypertrophic disorders of skin	0.009	0.991	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.009	0.991	0.000
C41.0 Bones of skull and face	0.009	0.991	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.009	0.991	0.000
D04.2 Skin of ear and external auricular canal	0.009	0.991	0.000
H18.7 Other corneal deformities	0.009	0.991	0.000
H18.3 Changes in corneal membranes	0.009	0.991	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.008	0.991	0.000
C74 Malignant neoplasm of adrenal gland	0.009	0.991	0.000
C13.9 Hypopharynx, unspecified	0.009	0.991	0.000
D05.0 Lobular carcinoma in situ	0.009	0.991	0.000
C60.8 Overlapping lesion of penis	0.008	0.991	0.000
C60.2 Body of penis	0.008	0.991	0.000
D09 Carcinoma in situ of other and unspecified sites	0.009	0.991	0.000
C60.9 Penis, unspecified	0.008	0.991	0.000
H20 Iridocyclitis	0.009	0.991	0.000
L40-L45 Papulosquamous disorders	0.009	0.991	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.008	0.991	0.000
L12.0 Bullous pemphigoid	0.008	0.991	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations