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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2285319
log Bayes Factor = 59.6334
Chromosome 6   position 30,887,972  (GRCh37) Explore rs2285319 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.003 0.997
E10.9 Without complications
0.000 0.005 0.995
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.007 0.993
L40.0 Psoriasis vulgaris
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.016 0.984
E10-E14 Diabetes mellitus
0.000 0.016 0.984
E10.4 With neurological complications
0.000 0.052 0.948
E10.3 With ophthalmic complications
0.000 0.090 0.910
E10.5 With peripheral circulatory complications
0.000 0.103 0.897
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.114 0.886
E50-E64 Other nutritional deficiencies
0.000 0.119 0.881
L40.8 Other psoriasis
0.855 0.145 0.000
L40.1 Generalised pustular psoriasis
0.844 0.156 0.000
E07 Other disorders of thyroid
0.000 0.170 0.830
E16 Other disorders of pancreatic internal secretion
0.000 0.184 0.816
E55 Vitamin D deficiency
0.000 0.190 0.810
E10.6 With other specified complications
0.000 0.195 0.805
E10.1 With ketoacidosis
0.000 0.197 0.803
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.198 0.802
E10.2 With renal complications
0.000 0.210 0.790
E10.0 With coma
0.000 0.220 0.780
E06 Thyroiditis
0.000 0.223 0.777
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.227 0.773
E16.2 Hypoglycaemia, unspecified
0.000 0.231 0.769
E07.9 Disorder of thyroid, unspecified
0.000 0.234 0.765
E55.9 Vitamin D deficiency, unspecified
0.000 0.241 0.759
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.723 0.277 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.722 0.278 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.720 0.280 0.000
T43.2 Other and unspecified antidepressants
0.717 0.283 0.000
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.285 0.714
E12 Malnutrition-related diabetes mellitus
0.000 0.295 0.705
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.700 0.300 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.657 0.343 0.000
E03.8 Other specified hypothyroidism
0.000 0.364 0.635
E15 Nondiabetic hypoglycaemic coma
0.000 0.365 0.635
E61 Deficiency of other nutrient elements
0.000 0.366 0.633
T43.0 Tricyclic and tetracyclic antidepressants
0.632 0.368 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.368 0.631
E63 Other nutritional deficiencies
0.000 0.368 0.631
E56 Other vitamin deficiencies
0.000 0.368 0.631
E51 Thiamine deficiency
0.000 0.368 0.631
E50 Vitamin A deficiency
0.000 0.368 0.631
E60 Dietary zinc deficiency
0.000 0.368 0.631
E59 Dietary selenium deficiency
0.000 0.368 0.631
E58 Dietary calcium deficiency
0.000 0.368 0.631
E54 Ascorbic acid deficiency
0.000 0.368 0.631
E52 Niacin deficiency [pellagra]
0.000 0.368 0.631
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.620 0.380 0.000
E53 Deficiency of other B group vitamins
0.000 0.381 0.619
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.383 0.617
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.611 0.389 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.611 0.389 0.000
E13 Other specified diabetes mellitus
0.000 0.398 0.602
E06.3 Autoimmune thyroiditis
0.000 0.398 0.602
T43.6 Psychostimulants with abuse potential
0.599 0.401 0.000
E07.1 Dyshormogenetic goitre
0.000 0.405 0.595
E07.0 Hypersecretion of calcitonin
0.000 0.405 0.595
T46 Poisoning by agents primarily affecting the cardiovascular system
0.592 0.408 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.586 0.414 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.414 0.586
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.415 0.585
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.415 0.585
E16.4 Abnormal secretion of gastrin
0.000 0.415 0.585
E16.3 Increased secretion of glucagon
0.000 0.415 0.585
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.584 0.416 0.000
E55.0 Rickets, active
0.000 0.419 0.581
E06.9 Thyroiditis, unspecified
0.000 0.425 0.575
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.565 0.435 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.562 0.438 0.000
E06.5 Other chronic thyroiditis
0.000 0.443 0.557
E06.4 Drug-induced thyroiditis
0.000 0.443 0.557
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.443 0.557
E06.1 Subacute thyroiditis
0.000 0.443 0.557
E06.0 Acute thyroiditis
0.000 0.443 0.557
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.555 0.445 0.000
E10.8 With unspecified complications
0.000 0.449 0.551
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.538 0.461 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.534 0.466 0.000
E16.1 Other hypoglycaemia
0.000 0.470 0.530
T47.1 Other antacids and anti-gastric-secretion drugs
0.521 0.479 0.000
T43.9 Psychotropic drug, unspecified
0.519 0.481 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.519 0.481 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.519 0.481 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.517 0.482 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.517 0.482 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.517 0.482 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.517 0.482 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.516 0.484 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.516 0.484 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.516 0.484 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.516 0.484 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.516 0.484 0.000
T44.0 Anticholinesterase agents
0.516 0.484 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
Chapter V Mental and behavioural disorders
0.510 0.490 0.000
F30-F39 Mood [affective] disorders
0.509 0.491 0.000
F33 Recurrent depressive disorder
0.509 0.491 0.000
E12.9 Without complications
0.000 0.494 0.506
E12.8 With unspecified complications
0.000 0.494 0.506
E12.7 With multiple complications
0.000 0.494 0.506
E12.6 With other specified complications
0.000 0.494 0.506
E12.5 With peripheral circulatory complications
0.000 0.494 0.506
E12.4 With neurological complications
0.000 0.494 0.506
E12.3 With ophthalmic complications
0.000 0.494 0.506
E12.2 With renal complications
0.000 0.494 0.506
E12.1 With ketoacidosis
0.000 0.494 0.506
E12.0 With coma
0.000 0.494 0.506
E40-E46 Malnutrition
0.001 0.496 0.504
T36 Poisoning by systemic antibiotics
0.504 0.496 0.000
F33.9 Recurrent depressive disorder, unspecified
0.501 0.499 0.000
T47.4 Other laxatives
0.490 0.510 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.486 0.514 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.486 0.514 0.000
F60-F69 Disorders of adult personality and behaviour
0.485 0.515 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.482 0.518 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.482 0.518 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.478 0.522 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.475 0.525 0.000
F60 Specific personality disorders
0.472 0.528 0.000
E61.2 Magnesium deficiency
0.000 0.530 0.470
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.469 0.531 0.000
F40 Phobic anxiety disorders
0.463 0.537 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.460 0.540 0.000
T45.0 Antiallergic and antiemetic drugs
0.457 0.542 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.546 0.454
E61.8 Deficiency of other specified nutrient elements
0.000 0.546 0.454
E61.7 Deficiency of multiple nutrient elements
0.000 0.546 0.454
E61.6 Vanadium deficiency
0.000 0.546 0.454
E61.5 Molybdenum deficiency
0.000 0.546 0.454
E61.4 Chromium deficiency
0.000 0.546 0.454
E61.3 Manganese deficiency
0.000 0.546 0.454
E61.0 Copper deficiency
0.000 0.546 0.454
T46.5 Other antihypertensive drugs, not elsewhere classified
0.454 0.546 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.453 0.547 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.547 0.453
E50.8 Other manifestations of vitamin A deficiency
0.000 0.547 0.453
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.547 0.453
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.547 0.453
E50.5 Vitamin A deficiency with night blindness
0.000 0.547 0.453
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.547 0.453
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.547 0.453
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.547 0.453
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.547 0.453
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.547 0.453
E51.9 Thiamine deficiency, unspecified
0.000 0.547 0.453
E51.8 Other manifestations of thiamine deficiency
0.000 0.547 0.453
E51.2 Wernicke's encephalopathy
0.000 0.547 0.453
E51.1 Beriberi
0.000 0.547 0.453
E56.9 Vitamin deficiency, unspecified
0.000 0.547 0.453
E56.8 Deficiency of other vitamins
0.000 0.547 0.453
E56.1 Deficiency of vitamin K
0.000 0.547 0.453
E56.0 Deficiency of vitamin E
0.000 0.547 0.453
E63.9 Nutritional deficiency, unspecified
0.000 0.547 0.453
E63.8 Other specified nutritional deficiencies
0.000 0.547 0.453
E63.1 Imbalance of constituents of food intake
0.000 0.547 0.453
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.547 0.453
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.547 0.453
E64.8 Sequelae of other nutritional deficiencies
0.000 0.547 0.453
E64.3 Sequelae of rickets
0.000 0.547 0.453
E64.2 Sequelae of vitamin C deficiency
0.000 0.547 0.453
E64.1 Sequelae of vitamin A deficiency
0.000 0.547 0.453
E64.0 Sequelae of protein-energy malnutrition
0.000 0.547 0.453
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.444 0.555 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.444 0.555 0.000
T47.7 Emetics
0.444 0.555 0.000
T47.6 Antidiarrhoeal drugs
0.444 0.555 0.000
T47.5 Digestants
0.444 0.555 0.000
T47.3 Saline and osmotic laxatives
0.444 0.555 0.000
T47.2 Stimulant laxatives
0.444 0.555 0.000
T47.0 Histamine H(2)-receptor antagonists
0.444 0.555 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.556 0.444
E53.1 Pyridoxine deficiency
0.000 0.556 0.444
E53.0 Riboflavin deficiency
0.000 0.556 0.444
E61.1 Iron deficiency
0.000 0.561 0.439
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.438 0.562 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.438 0.562 0.000
T42.3 Barbiturates
0.438 0.562 0.000
T42.2 Succinimides and oxazolidinediones
0.438 0.562 0.000
F60.3 Emotionally unstable personality disorder
0.433 0.567 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.432 0.567 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.568 0.432
E13.8 With unspecified complications
0.000 0.568 0.432
E13.7 With multiple complications
0.000 0.568 0.432
E13.6 With other specified complications
0.000 0.568 0.432
E13.5 With peripheral circulatory complications
0.000 0.568 0.432
E13.4 With neurological complications
0.000 0.568 0.432
E13.3 With ophthalmic complications
0.000 0.568 0.432
E13.2 With renal complications
0.000 0.568 0.432
E13.1 With ketoacidosis
0.000 0.568 0.432
E13.0 With coma
0.000 0.568 0.432
E04 Other non-toxic goitre
0.000 0.569 0.431
T38.1 Thyroid hormones and substitutes
0.431 0.569 0.000
F40.2 Specific (isolated) phobias
0.431 0.569 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.425 0.575 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.425 0.575 0.000
T46.7 Peripheral vasodilators
0.425 0.575 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.425 0.575 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.425 0.575 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.425 0.575 0.000
F34 Persistent mood [affective] disorders
0.422 0.578 0.000
F48 Other neurotic disorders
0.421 0.579 0.000
E67 Other hyperalimentation
0.000 0.580 0.420
E68 Sequelae of hyperalimentation
0.000 0.580 0.420
F52 Sexual dysfunction, not caused by organic disorder or disease
0.420 0.580 0.000
T38.9 Other and unspecified hormone antagonists
0.419 0.581 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.419 0.581 0.000
T38.7 Androgens and anabolic congeners
0.419 0.581 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.419 0.581 0.000
T38.5 Other oestrogens and progestogens
0.419 0.581 0.000
T38.4 Oral contraceptives
0.419 0.581 0.000
T38.2 Antithyroid drugs
0.419 0.581 0.000
T38.0 Glucocorticoids and synthetic analogues
0.419 0.581 0.000
K90 Intestinal malabsorption
0.000 0.582 0.418
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.416 0.583 0.000
T39.0 Salicylates
0.415 0.585 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.415 0.585 0.000
E66 Obesity
0.000 0.585 0.415
M07.30 Other psoriatic arthropathies (Multiple sites)
0.412 0.588 0.000
M07.3 Other psoriatic arthropathies
0.411 0.589 0.000
T46.1 Calcium-channel blockers
0.408 0.591 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.406 0.594 0.000
F11 Mental and behavioural disorders due to use of opioids
0.406 0.594 0.000
T50.8 Diagnostic agents
0.405 0.595 0.000
T50.7 Analeptics and opioid receptor antagonists
0.405 0.595 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.405 0.595 0.000
T50.5 Appetite depressants
0.405 0.595 0.000
T50.4 Drugs affecting uric acid metabolism
0.405 0.595 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.405 0.595 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.405 0.595 0.000
T50.1 Loop [high-ceiling] diuretics
0.405 0.595 0.000
T50.0 Mineralocorticoids and their antagonists
0.405 0.595 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.405 0.595 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.404 0.596 0.000
T42.0 Hydantoin derivatives
0.403 0.597 0.000
T42.1 Iminostilbenes
0.403 0.597 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.403 0.597 0.000
E14 Unspecified diabetes mellitus
0.000 0.597 0.403
F17 Mental and behavioural disorders due to use of tobacco
0.402 0.598 0.000
F30 Manic episode
0.401 0.599 0.000
F22 Persistent delusional disorders
0.400 0.600 0.000
F25 Schizoaffective disorders
0.398 0.602 0.000
F60.7 Dependent personality disorder
0.395 0.605 0.000
F44 Dissociative [conversion] disorders
0.393 0.607 0.000
E66.8 Other obesity
0.000 0.608 0.392
F50 Eating disorders
0.390 0.610 0.000
F32 Depressive episode
0.387 0.613 0.000
E07.8 Other specified disorders of thyroid
0.001 0.613 0.386
T45.9 Primarily systemic and haematological agent, unspecified
0.386 0.614 0.000
T45.8 Other primarily systemic and haematological agents
0.386 0.614 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.386 0.614 0.000
T45.6 Fibrinolysis-affecting drugs
0.386 0.614 0.000
T45.4 Iron and its compounds
0.386 0.614 0.000
T45.3 Enzymes, not elsewhere classified
0.386 0.614 0.000
T45.2 Vitamins, not elsewhere classified
0.386 0.614 0.000
F17.1 Harmful use
0.386 0.614 0.000
F52.2 Failure of genital response
0.385 0.615 0.000
F60.5 Anankastic personality disorder
0.385 0.615 0.000
F23 Acute and transient psychotic disorders
0.384 0.616 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.380 0.620 0.000
F12.1 Harmful use
0.378 0.622 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.372 0.628 0.000
F70-F79 Mental retardation
0.372 0.628 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.371 0.629 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.371 0.629 0.000
T37.5 Antiviral drugs
0.371 0.629 0.000
T37.4 Anthelminthics
0.371 0.629 0.000
T37.3 Other antiprotozoal drugs
0.371 0.629 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.371 0.629 0.000
T37.1 Antimycobacterial drugs
0.371 0.629 0.000
T37.0 Sulphonamides
0.371 0.629 0.000
T41.5 Therapeutic gases
0.371 0.629 0.000
T41.4 Anaesthetic, unspecified
0.371 0.629 0.000
T41.3 Local anaesthetics
0.371 0.629 0.000
T41.2 Other and unspecified general anaesthetics
0.371 0.629 0.000
T41.1 Intravenous anaesthetics
0.371 0.629 0.000
T41.0 Inhaled anaesthetics
0.371 0.629 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.371 0.629 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.371 0.629 0.000
T48.5 Anti-common-cold drugs
0.371 0.629 0.000
T48.4 Expectorants
0.371 0.629 0.000
T48.3 Antitussives
0.371 0.629 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.371 0.629 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.371 0.629 0.000
T48.0 Oxytocic drugs
0.371 0.629 0.000
T49.9 Topical agent, unspecified
0.371 0.629 0.000
T49.8 Other topical agents
0.371 0.629 0.000
T49.7 Dental drugs, topically applied
0.371 0.629 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.371 0.629 0.000
T49.5 Ophthalmological drugs and preparations
0.371 0.629 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.371 0.629 0.000
T49.3 Emollients, demulcents and protectants
0.371 0.629 0.000
T49.2 Local astringents and local detergents
0.371 0.629 0.000
T49.1 Antipruritics
0.371 0.629 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.371 0.629 0.000
F40.9 Phobic anxiety disorder, unspecified
0.370 0.630 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.370 0.630 0.000
F60.9 Personality disorder, unspecified
0.368 0.631 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.368 0.631 0.000
F42 Obsessive-compulsive disorder
0.368 0.632 0.000
T39.1 4-Aminophenol derivatives
0.368 0.632 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.366 0.634 0.000
F38 Other mood [affective] disorders
0.365 0.635 0.000
F33.8 Other recurrent depressive disorders
0.365 0.635 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.365 0.635 0.000
F48.0 Neurasthenia
0.362 0.638 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.638 0.361
E45 Retarded development following protein-energy malnutrition
0.001 0.638 0.361
E43 Unspecified severe protein-energy malnutrition
0.001 0.638 0.361
E42 Marasmic kwashiorkor
0.001 0.638 0.361
E41 Nutritional marasmus
0.001 0.638 0.361
E40 Kwashiorkor
0.001 0.638 0.361
T36.9 Systemic antibiotic, unspecified
0.361 0.639 0.000
T36.8 Other systemic antibiotics
0.361 0.639 0.000
T36.7 Antifungal antibiotics, systemically used
0.361 0.639 0.000
T36.6 Rifamycins
0.361 0.639 0.000
T36.5 Aminoglycosides
0.361 0.639 0.000
T36.4 Tetracyclines
0.361 0.639 0.000
T36.3 Macrolides
0.361 0.639 0.000
T36.2 Chloramphenicol group
0.361 0.639 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.361 0.639 0.000
F43 Reaction to severe stress, and adjustment disorders
0.360 0.640 0.000
F34.1 Dysthymia
0.359 0.641 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.358 0.642 0.000
F60.6 Anxious [avoidant] personality disorder
0.357 0.642 0.000
F22.0 Delusional disorder
0.357 0.643 0.000
F40.0 Agoraphobia
0.354 0.646 0.000
F69 Unspecified disorder of adult personality and behaviour
0.354 0.646 0.000
T42.4 Benzodiazepines
0.352 0.648 0.000
F32.0 Mild depressive episode
0.350 0.650 0.000
F68 Other disorders of adult personality and behaviour
0.348 0.652 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.348 0.652 0.000
F65 Disorders of sexual preference
0.348 0.652 0.000
F63 Habit and impulse disorders
0.348 0.652 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.348 0.652 0.000
F61 Mixed and other personality disorders
0.348 0.652 0.000
T36.0 Penicillins
0.347 0.652 0.000
F40.8 Other phobic anxiety disorders
0.346 0.654 0.000
F39 Unspecified mood [affective] disorder
0.346 0.654 0.000
T39.4 Antirheumatics, not elsewhere classified
0.345 0.654 0.000
T39.2 Pyrazolone derivatives
0.345 0.654 0.000
F25.9 Schizoaffective disorder, unspecified
0.344 0.656 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.342 0.658 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.341 0.659 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.341 0.659 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.341 0.659 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.341 0.659 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.659 0.340
F60.8 Other specific personality disorders
0.338 0.661 0.000
F60.4 Histrionic personality disorder
0.338 0.661 0.000
F60.2 Dissocial personality disorder
0.338 0.661 0.000
F60.1 Schizoid personality disorder
0.338 0.661 0.000
F60.0 Paranoid personality disorder
0.338 0.661 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.338 0.662 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.338 0.662 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.336 0.663 0.000
F51 Nonorganic sleep disorders
0.336 0.663 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.336 0.663 0.000
F55 Abuse of non-dependence-producing substances
0.336 0.663 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.336 0.663 0.000
E14.3 With ophthalmic complications
0.000 0.665 0.335
F40.1 Social phobias
0.332 0.668 0.000
F30.1 Mania without psychotic symptoms
0.330 0.670 0.000
F28 Other nonorganic psychotic disorders
0.330 0.670 0.000
F24 Induced delusional disorder
0.330 0.670 0.000
F21 Schizotypal disorder
0.330 0.670 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.330 0.670 0.000
F48.9 Neurotic disorder, unspecified
0.329 0.671 0.000
E13.9 Without complications
0.000 0.671 0.328
F30.2 Mania with psychotic symptoms
0.327 0.673 0.000
F11.2 Dependence syndrome
0.326 0.674 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.675 0.325
F43.2 Adjustment disorders
0.325 0.675 0.000
F20 Schizophrenia
0.322 0.678 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.321 0.678 0.000
F11.1 Harmful use
0.320 0.680 0.000
F25.0 Schizoaffective disorder, manic type
0.318 0.681 0.000
F50.0 Anorexia nervosa
0.315 0.685 0.000
F44.5 Dissociative convulsions
0.311 0.689 0.000
F11.3 Withdrawal state
0.311 0.689 0.000
F23.3 Other acute predominantly delusional psychotic disorders
0.310 0.690 0.000
E04.8 Other specified non-toxic goitre
0.000 0.690 0.309
E65 Localised adiposity
0.000 0.691 0.309
F45 Somatoform disorders
0.307 0.693 0.000
F44.9 Dissociative [conversion] disorder, unspecified
0.304 0.696 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.696 0.304
F34.9 Persistent mood [affective] disorder, unspecified
0.303 0.697 0.000
F34.8 Other persistent mood [affective] disorders
0.303 0.697 0.000
F34.0 Cyclothymia
0.303 0.697 0.000
F48.8 Other specified neurotic disorders
0.302 0.698 0.000
F48.1 Depersonalisation-derealisation syndrome
0.302 0.698 0.000
F50.9 Eating disorder, unspecified
0.302 0.698 0.000
E67.8 Other specified hyperalimentation
0.000 0.699 0.301
E67.3 Hypervitaminosis D
0.000 0.699 0.301
E67.2 Megavitamin-B6 syndrome
0.000 0.699 0.301
E67.1 Hypercarotenaemia
0.000 0.699 0.301
E67.0 Hypervitaminosis A
0.000 0.699 0.301
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease
0.301 0.699 0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease
0.301 0.699 0.000
F52.7 Excessive sexual drive
0.301 0.699 0.000
F52.6 Nonorganic dyspareunia
0.301 0.699 0.000
F52.5 Nonorganic vaginismus
0.301 0.699 0.000
F52.4 Premature ejaculation
0.301 0.699 0.000
F52.3 Orgasmic dysfunction
0.301 0.699 0.000
F52.1 Sexual aversion and lack of sexual enjoyment
0.301 0.699 0.000
F52.0 Lack or loss of sexual desire
0.301 0.699 0.000
F42.0 Predominantly obsessional thoughts or ruminations
0.300 0.700 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.700 0.300
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.700 0.300
K90.1 Tropical sprue
0.000 0.700 0.300
F12.9 Unspecified mental and behavioural disorder
0.298 0.702 0.000
F12.8 Other mental and behavioural disorders
0.298 0.702 0.000
F12.7 Residual and late-onset psychotic disorder
0.298 0.702 0.000
F12.6 Amnesic syndrome
0.298 0.702 0.000
F12.5 Psychotic disorder
0.298 0.702 0.000
F12.4 Withdrawal state with delirium
0.298 0.702 0.000
F12.3 Withdrawal state
0.298 0.702 0.000
F12.0 Acute intoxication
0.298 0.702 0.000
E66.1 Drug-induced obesity
0.000 0.702 0.298
M07.38 Other psoriatic arthropathies (Other)
0.295 0.705 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.295 0.705 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.295 0.705 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.295 0.705 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.295 0.705 0.000
F19.1 Harmful use
0.294 0.706 0.000
F64 Gender identity disorders
0.293 0.707 0.000
F32.9 Depressive episode, unspecified
0.292 0.708 0.000
F11.9 Unspecified mental and behavioural disorder
0.291 0.709 0.000
F11.8 Other mental and behavioural disorders
0.291 0.709 0.000
F11.7 Residual and late-onset psychotic disorder
0.291 0.709 0.000
F11.6 Amnesic syndrome
0.291 0.709 0.000
F11.5 Psychotic disorder
0.291 0.709 0.000
F11.4 Withdrawal state with delirium
0.291 0.709 0.000
F11.0 Acute intoxication
0.291 0.709 0.000
F32.8 Other depressive episodes
0.289 0.711 0.000
E14.7 With multiple complications
0.000 0.711 0.289
E14.6 With other specified complications
0.000 0.711 0.289
E14.2 Withrenal complications
0.000 0.711 0.289
E14.0 With coma
0.000 0.711 0.289
F17.9 Unspecified mental and behavioural disorder
0.288 0.712 0.000
F17.8 Other mental and behavioural disorders
0.288 0.712 0.000
F17.7 Residual and late-onset psychotic disorder
0.288 0.712 0.000
F17.6 Amnesic syndrome
0.288 0.712 0.000
F17.5 Psychotic disorder
0.288 0.712 0.000
F17.4 Withdrawal state with delirium
0.288 0.712 0.000
F17.3 Withdrawal state
0.288 0.712 0.000
F17.0 Acute intoxication
0.288 0.712 0.000
F30.8 Other manic episodes
0.287 0.713 0.000
F50.2 Bulimia nervosa
0.287 0.713 0.000
F22.9 Persistent delusional disorder, unspecified
0.287 0.713 0.000
F22.8 Other persistent delusional disorders
0.287 0.713 0.000
F25.8 Other schizoaffective disorders
0.286 0.714 0.000
F25.2 Schizoaffective disorder, mixed type
0.286 0.714 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.284 0.716 0.000
F44.8 Other dissociative [conversion] disorders
0.282 0.718 0.000
F44.7 Mixed dissociative [conversion] disorders
0.282 0.718 0.000
F44.6 Dissociative anaesthesia and sensory loss
0.282 0.718 0.000
F44.4 Dissociative motor disorders
0.282 0.718 0.000
F44.3 Trance and possession disorders
0.282 0.718 0.000
F44.2 Dissociative stupor
0.282 0.718 0.000
F44.1 Dissociative fugue
0.282 0.718 0.000
F44.0 Dissociative amnesia
0.282 0.718 0.000
F12.2 Dependence syndrome
0.282 0.718 0.000
E14.8 With unspecified complications
0.000 0.719 0.281
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.719 0.281
F50.8 Other eating disorders
0.280 0.720 0.000
F50.5 Vomiting associated with other psychological disturbances
0.280 0.720 0.000
F50.4 Overeating associated with other psychological disturbances
0.280 0.720 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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