TreeWAS – Variant ID: rs2286492

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H66 Suppurative and unspecified otitis media	0.057	0.943	0.000
H65-H75 Diseases of middle ear and mastoid	0.054	0.946	0.000
H66.3 Other chronic suppurative otitis media	0.053	0.947	0.000
H66.9 Otitis media, unspecified	0.051	0.949	0.000
Chapter VIII Diseases of the ear and mastoid process	0.049	0.951	0.000
H70 Mastoiditis and related conditions	0.049	0.951	0.000
H66.0 Acute suppurative otitis media	0.048	0.952	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.048	0.952	0.000
H60-H62 Diseases of external ear	0.047	0.953	0.000
H71 Cholesteatoma of middle ear	0.044	0.956	0.000
H80-H83 Diseases of inner ear	0.044	0.956	0.000
H60 Otitis externa	0.043	0.957	0.000
H61 Other disorders of external ear	0.042	0.958	0.000
H81 Disorders of vestibular function	0.042	0.958	0.000
H70.9 Mastoiditis, unspecified	0.042	0.958	0.000
H66.4 Suppurative otitis media, unspecified	0.041	0.959	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.041	0.959	0.000
H60.9 Otitis externa, unspecified	0.040	0.960	0.000
H72 Perforation of tympanic membrane	0.040	0.960	0.000
H61.8 Other specified disorders of external ear	0.040	0.960	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.039	0.961	0.000
H68 Eustachian salpingitis and obstruction	0.039	0.961	0.000
H67 Otitis media in diseases classified elsewhere	0.039	0.961	0.000
H70.8 Other mastoiditis and related conditions	0.038	0.961	0.000
H81.0 Meniere's disease	0.039	0.961	0.000
H70.1 Chronic mastoiditis	0.038	0.962	0.000
H73 Other disorders of tympanic membrane	0.038	0.962	0.000
H69 Other disorders of Eustachian tube	0.037	0.963	0.000
H80 Otosclerosis	0.036	0.964	0.000
H61.2 Impacted cerumen	0.036	0.964	0.000
H81.2 Vestibular neuronitis	0.035	0.965	0.000
H70.2 Petrositis	0.035	0.965	0.000
H70.0 Acute mastoiditis	0.035	0.965	0.000
H65 Nonsuppurative otitis media	0.035	0.965	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.034	0.966	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.034	0.966	0.000
H60.1 Cellulitis of external ear	0.032	0.968	0.000
H90-H95 Other disorders of ear	0.032	0.968	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.032	0.968	0.000
H60.5 Acute otitis externa, non-infective	0.031	0.969	0.000
H60.2 Malignant otitis externa	0.031	0.969	0.000
H60.0 Abscess of external ear	0.031	0.969	0.000
H81.3 Other peripheral vertigo	0.031	0.969	0.000
H60.4 Cholesteatoma of external ear	0.031	0.969	0.000
H72.1 Attic perforation of tympanic membrane	0.031	0.969	0.000
H80.9 Otosclerosis, unspecified	0.030	0.970	0.000
H61.9 Disorder of external ear, unspecified	0.030	0.970	0.000
H81.9 Disorder of vestibular function, unspecified	0.030	0.970	0.000
H81.8 Other disorders of vestibular function	0.030	0.970	0.000
H81.4 Vertigo of central origin	0.030	0.970	0.000
H60.3 Other infective otitis externa	0.030	0.970	0.000
H81.1 Benign paroxysmal vertigo	0.030	0.970	0.000
H74 Other disorders of middle ear and mastoid	0.030	0.970	0.000
H60.8 Other otitis externa	0.029	0.971	0.000
H65.4 Other chronic nonsuppurative otitis media	0.029	0.971	0.000
H72.8 Other perforations of tympanic membrane	0.028	0.971	0.000
H61.1 Non-infective disorders of pinna	0.028	0.972	0.000
H69.9 Eustachian tube disorder, unspecified	0.028	0.972	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.028	0.972	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.028	0.972	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.028	0.972	0.000
H68.1 Obstruction of Eustachian tube	0.028	0.972	0.000
H68.0 Eustachian salpingitis	0.028	0.972	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.028	0.972	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.028	0.972	0.000
H73.1 Chronic myringitis	0.027	0.973	0.000
H73.0 Acute myringitis	0.027	0.973	0.000
H73.8 Other specified disorders of tympanic membrane	0.027	0.973	0.000
H61.3 Acquired stenosis of external ear canal	0.027	0.973	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.027	0.973	0.000
H72.2 Other marginal perforations of tympanic membrane	0.027	0.973	0.000
H69.0 Patulous Eustachian tube	0.026	0.973	0.000
H80.8 Other otosclerosis	0.026	0.974	0.000
H80.2 Cochlear otosclerosis	0.026	0.974	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.026	0.974	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.026	0.974	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.026	0.974	0.000
H65.1 Other acute nonsuppurative otitis media	0.025	0.975	0.000
H65.0 Acute serous otitis media	0.025	0.975	0.000
H92 Otalgia and effusion of ear	0.025	0.975	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.024	0.975	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.024	0.975	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.024	0.975	0.000
H62.2 Otitis externa in mycoses	0.024	0.975	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.024	0.975	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.024	0.975	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.024	0.976	0.000
H83 Other diseases of inner ear	0.023	0.977	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.023	0.977	0.000
H61.0 Perichondritis of external ear	0.023	0.977	0.000
H72.0 Central perforation of tympanic membrane	0.023	0.977	0.000
H90 Conductive and sensorineural hearing loss	0.022	0.978	0.000
H65.2 Chronic serous otitis media	0.022	0.978	0.000
H69.8 Other specified disorders of Eustachian tube	0.022	0.978	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.021	0.978	0.000
H74.1 Adhesive middle ear disease	0.021	0.978	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.021	0.979	0.000
H91 Other hearing loss	0.021	0.979	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.021	0.979	0.000
H74.0 Tympanosclerosis	0.021	0.979	0.000
H95.1 Other disorders following mastoidectomy	0.021	0.979	0.000
H92.0 Otalgia	0.021	0.979	0.000
H74.4 Polyp of middle ear	0.020	0.980	0.000
H90.2 Conductive hearing loss, unspecified	0.020	0.980	0.000
H65.3 Chronic mucoid otitis media	0.019	0.981	0.000
M54.56 Low back pain (Lumbar region)	0.000	0.981	0.019
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.018	0.981	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.018	0.981	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.018	0.981	0.000
H83.9 Disease of inner ear, unspecified	0.018	0.981	0.000
H90.0 Conductive hearing loss, bilateral	0.018	0.982	0.000
H92.2 Otorrhagia	0.018	0.982	0.000
H93 Other disorders of ear, not elsewhere classified	0.018	0.982	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.018	0.982	0.000
H83.8 Other specified diseases of inner ear	0.017	0.983	0.000
H83.3 Noise effects on inner ear	0.017	0.983	0.000
H83.2 Labyrinthine dysfunction	0.017	0.983	0.000
H83.1 Labyrinthine fistula	0.017	0.983	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.017	0.983	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.017	0.983	0.000
H91.3 Deaf mutism, not elsewhere classified	0.016	0.984	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.016	0.984	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.016	0.984	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.016	0.984	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.016	0.984	0.000
H91.2 Sudden idiopathic hearing loss	0.016	0.984	0.000
H91.1 Presbycusis	0.016	0.984	0.000
H91.0 Ototoxic hearing loss	0.016	0.984	0.000
H92.1 Otorrhoea	0.015	0.984	0.000
H91.8 Other specified hearing loss	0.015	0.985	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.015	0.985	0.000
H91.9 Hearing loss, unspecified	0.013	0.987	0.000
H93.3 Disorders of acoustic nerve	0.013	0.987	0.000
H93.2 Other abnormal auditory perceptions	0.013	0.987	0.000
H93.0 Degenerative and vascular disorders of ear	0.013	0.987	0.000
H93.9 Disorder of ear, unspecified	0.012	0.988	0.000
H93.8 Other specified disorders of ear	0.011	0.988	0.000
H93.1 Tinnitus	0.011	0.989	0.000
H90.5 Sensorineural hearing loss, unspecified	0.011	0.989	0.000
H90.3 Sensorineural hearing loss, bilateral	0.010	0.989	0.000
M54.5 Low back pain	0.000	0.993	0.007
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.007	0.993	0.000
M54.50 Low back pain (Multiple sites in spine)	0.000	0.993	0.007
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.000	0.994	0.006
R59.9 Enlarged lymph nodes, unspecified	0.000	0.994	0.006
J03.9 Acute tonsillitis, unspecified	0.006	0.994	0.000
H52.1 Myopia	0.006	0.994	0.000
M54.54 Low back pain-Thoracic	0.000	0.995	0.005
M54.53 Low back pain-Cervicothoracic	0.000	0.995	0.005
M54.52 Low back pain-Cervical	0.000	0.995	0.005
M54.51 Low back pain-Occipit-atl-axl	0.000	0.995	0.005
M54.55 Low back pain (Thoracolumbar region)	0.000	0.995	0.005
R21 Rash and other nonspecific skin eruption	0.005	0.995	0.000
M24.2 Disorder of ligament	0.005	0.995	0.000
M24.23 Disorder of ligament (Forearm)	0.005	0.995	0.000
M24.26 Disorder of ligament (Lower leg)	0.004	0.996	0.000
R59 Enlarged lymph nodes	0.000	0.996	0.004
R59.0 Localised enlarged lymph nodes	0.000	0.996	0.004
N43.3 Hydrocele, unspecified	0.000	0.996	0.004
D48.5 Skin	0.004	0.996	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.996	0.004
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.004	0.996	0.000
H83.0 Labyrinthitis	0.003	0.996	0.001
M24.24 Disorder of ligament (Hand)	0.004	0.996	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.004	0.996	0.000
M23.8 Other internal derangements of knee	0.004	0.996	0.000
E55.9 Vitamin D deficiency, unspecified	0.004	0.996	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.996	0.004
M23.3 Other meniscus derangements	0.004	0.996	0.000
M24 Other specific joint derangements	0.004	0.996	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.004	0.996	0.000
M24.29 Disorder of ligament (Site unspecified)	0.003	0.996	0.000
M24.28 Disorder of ligament (Other)	0.003	0.996	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.003	0.996	0.000
M24.22 Disorder of ligament (Upper arm)	0.003	0.996	0.000
M24.21 Disorder of ligament (Shoulder region)	0.003	0.996	0.000
M24.20 Disorder of ligament (Multiple sites)	0.003	0.996	0.000
R56.8 Other and unspecified convulsions	0.000	0.996	0.004
M25.57 Pain in joint (Ankle and foot)	0.004	0.996	0.000
S92.00 Fracture of calcaneus (closed)	0.004	0.996	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.003	0.997	0.000
Z95.2 Presence of prosthetic heart valve	0.003	0.997	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.003	0.997	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.997	0.003
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
M24.0 Loose body in joint	0.003	0.997	0.000
R19.5 Other fecal abnormalities	0.000	0.997	0.003
H52 Disorders of refraction and accommodation	0.003	0.997	0.000
M23 Internal derangement of knee	0.003	0.997	0.000
M24.6 Ankylosis of joint	0.003	0.997	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.003	0.997	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.003	0.997	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.997	0.003
M24.8 Other specific joint derangements, not elsewhere classified	0.003	0.997	0.000
J03 Acute tonsillitis	0.003	0.997	0.000
H52.2 Astigmatism	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.000	0.997	0.003
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.003	0.997	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.003	0.997	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.003	0.997	0.000
J18.9 Pneumonia, unspecified	0.003	0.997	0.000
M23.1 Discoid meniscus (congenital)	0.003	0.997	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.003	0.997	0.000
S02.4 Fracture of malar and maxillary bones	0.000	0.997	0.003
M23.37 Other meniscus derangements-Capsular lig	0.003	0.997	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.003	0.997	0.000
D18.0 Haemangioma, any site	0.003	0.997	0.000
H50.2 Vertical strabismus	0.003	0.997	0.000
M24.9 Joint derangement, unspecified	0.003	0.997	0.000
M24.7 Protrusio acetabuli	0.003	0.997	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.003	0.997	0.000
M24.1 Other articular cartilage disorders	0.003	0.997	0.000
R00.0 Tachycardia, unspecified	0.003	0.997	0.000
J09-J18 Influenza and pneumonia	0.003	0.997	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.000	0.997	0.003
M24.02 Loose body in joint (Upper arm)	0.003	0.997	0.000
M23.9 Internal derangement of knee, unspecified	0.003	0.997	0.000
M24.03 Loose body in joint (Forearm)	0.003	0.997	0.000
M23.0 Cystic meniscus	0.003	0.997	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.003	0.997	0.000
J10 Influenza due to identified influenza virus	0.003	0.997	0.000
M24.66 Ankylosis of joint (Lower leg)	0.003	0.997	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.997	0.003
N76.2 Acute vulvitis	0.000	0.997	0.003
S02.0 Fracture of vault of skull	0.000	0.997	0.003
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.003	0.997	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.003	0.997	0.000
N18.3 Chronic kidney disease, stage 3	0.003	0.997	0.000
J17 Pneumonia in diseases classified elsewhere	0.003	0.997	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M24.5 Contracture of joint	0.003	0.997	0.000
J12 Viral pneumonia, not elsewhere classified	0.003	0.997	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.003	0.997	0.000
J18.0 Bronchopneumonia, unspecified	0.003	0.997	0.000
H50 Other strabismus	0.003	0.997	0.000
J18 Pneumonia, organism unspecified	0.003	0.997	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.003	0.997	0.000
M24.09 Loose body in joint (Site unspecified)	0.003	0.997	0.000
M24.08 Loose body in joint (Other)	0.003	0.997	0.000
M24.06 Loose body in joint-Lower leg	0.003	0.997	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.04 Loose body in joint (Hand)	0.003	0.997	0.000
M24.01 Loose body in joint (Shoulder region)	0.003	0.997	0.000
M24.00 Loose body in joint (Multiple sites)	0.003	0.997	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.003	0.997	0.000
M24.07 Loose body in joint (Ankle and foot)	0.003	0.997	0.000
J12.9 Viral pneumonia, unspecified	0.003	0.997	0.000
M23.4 Loose body in knee	0.003	0.997	0.000
S02.2 Fracture of nasal bones	0.000	0.997	0.003
J11 Influenza, virus not identified	0.003	0.997	0.000
J43.9 Emphysema, unspecified	0.003	0.997	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.002	0.997	0.000
R10.4 Other and unspecified abdominal pain	0.003	0.997	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.002	0.997	0.000
S02.8 Fractures of other skull and facial bones	0.000	0.997	0.003
H52.6 Other disorders of refraction	0.002	0.997	0.000
H52.5 Disorders of accommodation	0.002	0.997	0.000
H52.4 Presbyopia	0.002	0.997	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.997	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.002	0.997	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.002	0.997	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.002	0.997	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.002	0.997	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.002	0.997	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.002	0.997	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.002	0.997	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.002	0.997	0.000
M24.68 Ankylosis of joint (Other)	0.002	0.997	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.002	0.997	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.002	0.997	0.000
M24.64 Ankylosis of joint (Hand)	0.002	0.997	0.000
M24.63 Ankylosis of joint (Forearm)	0.002	0.997	0.000
M24.62 Ankylosis of joint (Upper arm)	0.002	0.997	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.002	0.997	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.002	0.997	0.000
M54.57 Low back pain (Lumbosacral region)	0.000	0.997	0.003
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.997	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.997	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.997	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.997	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.997	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.997	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.997	0.000
J03.8 Acute tonsillitis due to other specified organisms	0.002	0.997	0.000
J03.0 Streptococcal tonsillitis	0.002	0.997	0.000
S02.11 Fracture of base of skull (open)	0.000	0.997	0.002
S02.20 Fracture of nasal bones (closed)	0.000	0.997	0.002
J11.0 Influenza with pneumonia, virus not identified	0.002	0.997	0.000
M77.1 Lateral epicondylitis	0.002	0.997	0.000
N84.1 Polyp of cervix uteri	0.000	0.997	0.003
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.002	0.998	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.002	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.002	0.998	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.998	0.002
C67.9 Bladder, unspecified	0.002	0.998	0.000
D48.7 Other specified sites	0.002	0.998	0.000
H52.3 Anisometropia and aniseikonia	0.002	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
N82.3 Fistula of vagina to large intestine	0.002	0.998	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.002	0.998	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M24.79 Protrusio acetabuli-Site unspec	0.002	0.998	0.000
M24.78 Protrusio acetabuli-Other	0.002	0.998	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.002	0.998	0.000
M24.76 Protrusio acetabuli-Lower leg	0.002	0.998	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.002	0.998	0.000
M24.74 Protrusio acetabuli-Hand	0.002	0.998	0.000
M24.73 Protrusio acetabuli-Forearm	0.002	0.998	0.000
M24.72 Protrusio acetabuli-Upper arm	0.002	0.998	0.000
M24.71 Protrusio acetabuli-Shldr region	0.002	0.998	0.000
M24.70 Protrusio acetabuli-Mult sites	0.002	0.998	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.002	0.998	0.000
M24.98 Joint derangement, unspecified (Other)	0.002	0.998	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.002	0.998	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.002	0.998	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M24.94 Joint derangement, unspecified (Hand)	0.002	0.998	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.002	0.998	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.002	0.998	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.002	0.998	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.002	0.998	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.002	0.998	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.002	0.998	0.000
C67.6 Ureteric orifice	0.002	0.998	0.000
C67.1 Dome of bladder	0.002	0.998	0.000
S02.6 Fracture of mandible	0.000	0.998	0.002
M24.19 Other articular cartilage disorders (Site unspecified)	0.002	0.998	0.000
M24.18 Other articular cartilage disorders (Other)	0.002	0.998	0.000
M24.14 Other articular cartilage disorders (Hand)	0.002	0.998	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.002	0.998	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.002	0.998	0.000
H50.5 Heterophoria	0.002	0.998	0.000
C67 Malignant neoplasm of bladder	0.002	0.998	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.002	0.998	0.000
J09 Influenza due to certain identified influenza virus	0.002	0.998	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.002	0.998	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.002	0.998	0.000
M24.56 Contracture of joint (Lower leg)	0.002	0.998	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M23.07 Cystic meniscus-Capsular lig	0.002	0.998	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M23.00 Cystic meniscus (Multiple sites)	0.002	0.998	0.000
N32.9 Bladder disorder, unspecified	0.002	0.998	0.000
M23.46 Loose body in knee-O/unsp lat men	0.002	0.998	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.002	0.998	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.002	0.998	0.000
N23 Unspecified renal colic	0.000	0.998	0.002
S02.01 Fracture of vault of skull (open)	0.000	0.998	0.002
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.998	0.002
H52.7 Disorder of refraction, unspecified	0.002	0.998	0.000
J15.9 Bacterial pneumonia, unspecified	0.002	0.998	0.000
J15.8 Other bacterial pneumonia	0.002	0.998	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.002	0.998	0.000
J15.5 Pneumonia due to Escherichia coli	0.002	0.998	0.000
J15.4 Pneumonia due to other streptococci	0.002	0.998	0.000
J15.3 Pneumonia due to streptococcus, group B	0.002	0.998	0.000
S02.5 Fracture of tooth	0.000	0.998	0.002
J17.8 Pneumonia in other diseases classified elsewhere	0.002	0.998	0.000
J17.2 Pneumonia in mycoses	0.002	0.998	0.000
J17.1 Pneumonia in viral diseases classified elsewhere	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
M24.59 Contracture of joint (Site unspecified)	0.002	0.998	0.000
M24.58 Contracture of joint (Other)	0.002	0.998	0.000
M24.57 Contracture of joint (Ankle and foot)	0.002	0.998	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.002	0.998	0.000
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.002	0.998	0.000
J12.8 Other viral pneumonia	0.002	0.998	0.000
J12.3 Human metapneumovirus pneumonia	0.002	0.998	0.000
J12.2 Parainfluenza virus pneumonia	0.002	0.998	0.000
J12.1 Respiratory syncytial virus pneumonia	0.002	0.998	0.000
J12.0 Adenoviral pneumonia	0.002	0.998	0.000
J43 Emphysema	0.002	0.998	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
H50.9 Strabismus, unspecified	0.002	0.998	0.000
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.002	0.998	0.000
M77.4 Metatarsalgia	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.000	0.998	0.002
J14 Pneumonia due to Haemophilus influenzae	0.002	0.998	0.000
H50.8 Other specified strabismus	0.002	0.998	0.000
H50.6 Mechanical strabismus	0.002	0.998	0.000
H50.3 Intermittent heterotropia	0.002	0.998	0.000
J18.8 Other pneumonia, organism unspecified	0.002	0.998	0.000
J18.2 Hypostatic pneumonia, unspecified	0.002	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.998	0.002
S92.0 Fracture of calcaneus	0.002	0.998	0.000
M23.43 Loose body in knee-Med lig/oth men	0.002	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.002	0.998	0.000
H50.4 Other and unspecified heterotropia	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.000	0.998	0.002
J40 Bronchitis, not specified as acute or chronic	0.002	0.998	0.000
M23.47 Loose body in knee-Capsular lig	0.002	0.998	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.002	0.998	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.002	0.998	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.002	0.998	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.002	0.998	0.000
M23.40 Loose body in knee-Mult sites	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
J11.8 Influenza with other manifestations, virus not identified	0.002	0.998	0.000
M24.51 Contracture of joint (Shoulder region)	0.002	0.998	0.000
M23.5 Chronic instability of knee	0.002	0.998	0.000
S02.81 Fractures of other skull and facial bones (open)	0.000	0.998	0.002
J11.1 Influenza with other respiratory manifestations, virus not identified	0.002	0.998	0.000
J15.2 Pneumonia due to staphylococcus	0.002	0.998	0.000
J43.2 Centrilobular emphysema	0.002	0.998	0.000
M77.9 Enthesopathy, unspecified	0.002	0.998	0.000
M77 Other enthesopathies	0.002	0.998	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
C67.4 Posterior wall of bladder	0.002	0.998	0.000
C67.3 Anterior wall of bladder	0.002	0.998	0.000
C67.0 Trigone of bladder	0.002	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
M54.59 Low back pain (Site unspecified)	0.000	0.998	0.002
M77.19 Lateral epicondylitis (Site unspecified)	0.002	0.998	0.000
M77.18 Lateral epicondylitis-Other	0.002	0.998	0.000
M77.17 Lateral epicondylitis-Ankle/Foot	0.002	0.998	0.000
M77.16 Lateral epicondylitis (Lower leg)	0.002	0.998	0.000
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.002	0.998	0.000
M77.14 Lateral epicondylitis-Hand	0.002	0.998	0.000
M77.13 Lateral epicondylitis-Forearm	0.002	0.998	0.000
M77.11 Lateral epicondylitis-Shldr region	0.002	0.998	0.000
M77.10 Lateral epicondylitis (Multiple sites)	0.002	0.998	0.000
J17.3 Pneumonia in parasitic diseases	0.002	0.998	0.000
M23.49 Loose body in knee-Unspec lig/men	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.002	0.998	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.002	0.998	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.002	0.998	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
E55 Vitamin D deficiency	0.002	0.998	0.000
H49 Paralytic strabismus	0.002	0.998	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.002	0.998	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
D48.0 Bone and articular cartilage	0.002	0.998	0.000
M77.0 Medial epicondylitis	0.002	0.998	0.000
N60.4 Mammary duct ectasia	0.000	0.998	0.002
S02.61 Fracture of mandible (open)	0.000	0.998	0.002
S02.60 Fracture of mandible (closed)	0.000	0.998	0.002
E83.1 Disorders of iron metabolism	0.002	0.998	0.000
H51 Other disorders of binocular movement	0.002	0.998	0.000
C67.8 Overlapping lesion of bladder	0.002	0.998	0.000
C67.7 Urachus	0.002	0.998	0.000
J16.8 Pneumonia due to other specified infectious organisms	0.002	0.998	0.000
J16.0 Chlamydial pneumonia	0.002	0.998	0.000
C67.2 Lateral wall of bladder	0.002	0.998	0.000
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
Q61 Cystic kidney disease	0.002	0.998	0.000
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.998	0.000
D48.4 Peritoneum	0.002	0.998	0.000
D48.3 Retroperitoneum	0.002	0.998	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.998	0.002
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
M77.02 Medial epicondylitis (Upper arm)	0.002	0.998	0.000
S02.51 Fracture of tooth (open)	0.000	0.998	0.002
J43.8 Other emphysema	0.002	0.998	0.000
J43.1 Panlobular emphysema	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations