TreeWAS – Variant ID: rs2290402

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T43.0 Tricyclic and tetracyclic antidepressants	0.034	0.966	0.000
K60.2 Anal fissure, unspecified	0.033	0.967	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.032	0.968	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.030	0.970	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.030	0.970	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.029	0.971	0.000
T42.4 Benzodiazepines	0.028	0.972	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.026	0.974	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.025	0.975	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.024	0.975	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.024	0.976	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.023	0.977	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.023	0.977	0.000
T43.9 Psychotropic drug, unspecified	0.023	0.977	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.023	0.977	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.023	0.977	0.000
T36 Poisoning by systemic antibiotics	0.022	0.978	0.000
T43.2 Other and unspecified antidepressants	0.022	0.978	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.021	0.978	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.021	0.978	0.000
T42.3 Barbiturates	0.021	0.978	0.000
T42.2 Succinimides and oxazolidinediones	0.021	0.978	0.000
T42.0 Hydantoin derivatives	0.021	0.978	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.021	0.978	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.021	0.978	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.021	0.978	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.021	0.978	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.021	0.978	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.022	0.978	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.021	0.978	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.021	0.979	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.021	0.979	0.000
T47.6 Antidiarrhoeal drugs	0.020	0.980	0.000
G20 Parkinson's disease	0.020	0.980	0.000
T43.6 Psychostimulants with abuse potential	0.019	0.980	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.019	0.981	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.019	0.981	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.019	0.981	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.019	0.981	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.019	0.981	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.018	0.981	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.018	0.982	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.018	0.982	0.000
T40.2 Other opioids	0.018	0.982	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.018	0.982	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.018	0.982	0.000
T47.7 Emetics	0.018	0.982	0.000
T47.5 Digestants	0.018	0.982	0.000
T47.4 Other laxatives	0.018	0.982	0.000
T47.3 Saline and osmotic laxatives	0.018	0.982	0.000
T47.2 Stimulant laxatives	0.018	0.982	0.000
T47.0 Histamine H(2)-receptor antagonists	0.018	0.982	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.017	0.982	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.017	0.982	0.000
T46.7 Peripheral vasodilators	0.017	0.982	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.017	0.982	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.017	0.982	0.000
T42.1 Iminostilbenes	0.017	0.982	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.017	0.983	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.017	0.983	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.017	0.983	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.017	0.983	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.017	0.983	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.017	0.983	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.017	0.983	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.017	0.983	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.017	0.983	0.000
T44.0 Anticholinesterase agents	0.017	0.983	0.000
T36.0 Penicillins	0.017	0.983	0.000
T46.1 Calcium-channel blockers	0.016	0.984	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.016	0.984	0.000
T36.9 Systemic antibiotic, unspecified	0.016	0.984	0.000
T36.8 Other systemic antibiotics	0.016	0.984	0.000
T36.7 Antifungal antibiotics, systemically used	0.016	0.984	0.000
T36.6 Rifamycins	0.016	0.984	0.000
T36.5 Aminoglycosides	0.016	0.984	0.000
T36.4 Tetracyclines	0.016	0.984	0.000
T36.3 Macrolides	0.016	0.984	0.000
T36.2 Chloramphenicol group	0.016	0.984	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.016	0.984	0.000
T39.0 Salicylates	0.016	0.984	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.016	0.984	0.000
T45.8 Other primarily systemic and haematological agents	0.016	0.984	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.016	0.984	0.000
T45.6 Fibrinolysis-affecting drugs	0.016	0.984	0.000
T45.4 Iron and its compounds	0.016	0.984	0.000
T45.3 Enzymes, not elsewhere classified	0.016	0.984	0.000
T38.9 Other and unspecified hormone antagonists	0.016	0.984	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.016	0.984	0.000
T38.7 Androgens and anabolic congeners	0.016	0.984	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.016	0.984	0.000
T38.5 Other oestrogens and progestogens	0.016	0.984	0.000
T38.4 Oral contraceptives	0.016	0.984	0.000
T38.2 Antithyroid drugs	0.016	0.984	0.000
T38.0 Glucocorticoids and synthetic analogues	0.016	0.984	0.000
T39.4 Antirheumatics, not elsewhere classified	0.016	0.984	0.000
T39.2 Pyrazolone derivatives	0.016	0.984	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.015	0.984	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.015	0.984	0.000
T37.5 Antiviral drugs	0.015	0.984	0.000
T37.4 Anthelminthics	0.015	0.984	0.000
T37.3 Other antiprotozoal drugs	0.015	0.984	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.015	0.984	0.000
T37.1 Antimycobacterial drugs	0.015	0.984	0.000
T37.0 Sulphonamides	0.015	0.984	0.000
T41.5 Therapeutic gases	0.015	0.984	0.000
T41.4 Anaesthetic, unspecified	0.015	0.984	0.000
T41.3 Local anaesthetics	0.015	0.984	0.000
T41.2 Other and unspecified general anaesthetics	0.015	0.984	0.000
T41.1 Intravenous anaesthetics	0.015	0.984	0.000
T41.0 Inhaled anaesthetics	0.015	0.984	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.015	0.984	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.015	0.984	0.000
T48.5 Anti-common-cold drugs	0.015	0.984	0.000
T48.4 Expectorants	0.015	0.984	0.000
T48.3 Antitussives	0.015	0.984	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.015	0.984	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.015	0.984	0.000
T48.0 Oxytocic drugs	0.015	0.984	0.000
T49.9 Topical agent, unspecified	0.015	0.984	0.000
T49.8 Other topical agents	0.015	0.984	0.000
T49.7 Dental drugs, topically applied	0.015	0.984	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.015	0.984	0.000
T49.5 Ophthalmological drugs and preparations	0.015	0.984	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.015	0.984	0.000
T49.3 Emollients, demulcents and protectants	0.015	0.984	0.000
T49.2 Local astringents and local detergents	0.015	0.984	0.000
T49.1 Antipruritics	0.015	0.984	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.015	0.984	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.015	0.985	0.000
T40.8 Lysergide [LSD]	0.015	0.985	0.000
T40.7 Cannabis (derivatives)	0.015	0.985	0.000
T40.5 Cocaine	0.015	0.985	0.000
T40.3 Methadone	0.015	0.985	0.000
T40.1 Heroin	0.015	0.985	0.000
T40.0 Opium	0.015	0.985	0.000
T45.0 Antiallergic and antiemetic drugs	0.015	0.985	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.015	0.985	0.000
T45.2 Vitamins, not elsewhere classified	0.015	0.985	0.000
T38.1 Thyroid hormones and substitutes	0.015	0.985	0.000
T40.6 Other and unspecified narcotics	0.014	0.986	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.014	0.986	0.000
G20-G26 Extrapyramidal and movement disorders	0.013	0.987	0.000
T50.8 Diagnostic agents	0.012	0.987	0.000
T50.7 Analeptics and opioid receptor antagonists	0.012	0.987	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.012	0.987	0.000
T50.5 Appetite depressants	0.012	0.987	0.000
T50.4 Drugs affecting uric acid metabolism	0.012	0.987	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.012	0.987	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.012	0.987	0.000
T50.1 Loop [high-ceiling] diuretics	0.012	0.987	0.000
T50.0 Mineralocorticoids and their antagonists	0.012	0.987	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.988	0.012
T40.4 Other synthetic narcotics	0.012	0.988	0.000
G24 Dystonia	0.011	0.989	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.989	0.011
T45.5 Anticoagulants	0.010	0.989	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.989	0.011
G24.9 Dystonia, unspecified	0.010	0.990	0.000
G25 Other extrapyramidal and movement disorders	0.010	0.990	0.000
G23 Other degenerative diseases of basal ganglia	0.009	0.991	0.000
G21 Secondary Parkinsonism	0.009	0.991	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.009	0.991	0.000
G22 Parkinsonism in diseases classified elsewhere	0.009	0.991	0.000
G24.8 Other dystonia	0.009	0.991	0.000
G25.0 Essential tremor	0.009	0.991	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.008	0.992	0.000
G25.5 Other chorea	0.008	0.992	0.000
N90.5 Atrophy of vulva	0.008	0.992	0.000
G24.4 Idiopathic orofacial dystonia	0.008	0.992	0.000
G24.2 Idiopathic nonfamilial dystonia	0.008	0.992	0.000
G24.1 Idiopathic familial dystonia	0.008	0.992	0.000
G24.0 Drug-induced dystonia	0.008	0.992	0.000
G25.3 Myoclonus	0.008	0.992	0.000
G24.3 Spasmodic torticollis	0.008	0.992	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.992	0.008
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.992	0.008
D51.2 Transcobalamin II deficiency	0.000	0.992	0.008
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.992	0.008
G25.9 Extrapyramidal and movement disorder, unspecified	0.008	0.992	0.000
E55.9 Vitamin D deficiency, unspecified	0.008	0.992	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.007	0.992	0.000
G25.4 Drug-induced chorea	0.007	0.992	0.000
G25.2 Other specified forms of tremor	0.007	0.992	0.000
G25.1 Drug-induced tremor	0.007	0.992	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.008	0.992	0.000
G21.9 Secondary Parkinsonism, unspecified	0.007	0.993	0.000
G21.8 Other secondary Parkinsonism	0.007	0.993	0.000
G21.4 Vascular parkinsonism	0.007	0.993	0.000
G21.3 Postencephalitic Parkinsonism	0.007	0.993	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.007	0.993	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.007	0.993	0.000
G21.0 Malignant neuroleptic syndrome	0.007	0.993	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.007	0.993	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.007	0.993	0.000
G23.3 Multiple system atrophy, cerebellar type	0.007	0.993	0.000
G23.2 Striatonigral degeneration	0.007	0.993	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.007	0.993	0.000
G23.0 Hallervorden-Spatz disease	0.007	0.993	0.000
N90.7 Vulvar cyst	0.007	0.993	0.000
N90.1 Moderate vulvar dysplasia	0.007	0.993	0.000
G24.5 Blepharospasm	0.007	0.993	0.000
N90.3 Dysplasia of vulva, unspecified	0.006	0.994	0.000
N90.6 Hypertrophy of vulva	0.006	0.994	0.000
D24 Benign neoplasm of breast	0.000	0.994	0.006
V23.4 Driver injured in traffic accident	0.000	0.994	0.006
N90.4 Leukoplakia of vulva	0.006	0.994	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.006	0.994	0.000
N90.0 Mild vulvar dysplasia	0.006	0.994	0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.006	0.994	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.005	0.995	0.000
H93.1 Tinnitus	0.000	0.995	0.005
C78.0 Secondary malignant neoplasm of lung	0.005	0.995	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.005	0.995	0.000
Q05.9 Spina bifida, unspecified	0.004	0.996	0.000
Q05 Spina bifida	0.004	0.996	0.000
T39.1 4-Aminophenol derivatives	0.004	0.996	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.004	0.996	0.000
E55 Vitamin D deficiency	0.004	0.996	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.004	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.996	0.004
Q07.0 Arnold-Chiari syndrome	0.004	0.996	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.996	0.004
Q07 Other congenital malformations of nervous system	0.004	0.996	0.000
N73.6 Female pelvic peritoneal adhesions	0.004	0.996	0.000
H93.9 Disorder of ear, unspecified	0.000	0.997	0.003
Q05.8 Sacral spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.003	0.997	0.000
L89.1 Stage II decubitus ulcer	0.000	0.997	0.003
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.000	0.997	0.003
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.997	0.003
Q03 Congenital hydrocephalus	0.003	0.997	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.997	0.003
D50-D53 Nutritional anaemias	0.000	0.997	0.003
Q04 Other congenital malformations of brain	0.003	0.997	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.997	0.003
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.997	0.003
E55.0 Rickets, active	0.003	0.997	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.997	0.003
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
Q83.1 Accessory breast	0.003	0.997	0.000
H93.3 Disorders of acoustic nerve	0.000	0.997	0.003
H93.2 Other abnormal auditory perceptions	0.000	0.997	0.003
H93.0 Degenerative and vascular disorders of ear	0.000	0.997	0.003
Q07.9 Congenital malformation of nervous system, unspecified	0.003	0.997	0.000
Q07.8 Other specified congenital malformations of nervous system	0.003	0.997	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.997	0.003
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.997	0.000
H93.8 Other specified disorders of ear	0.000	0.997	0.003
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
L89 Decubitus ulcer	0.000	0.997	0.003
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.997	0.003
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.997	0.003
V23.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.997	0.002
V23.5 Passenger injured in traffic accident	0.000	0.997	0.002
V23.3 Person injured while boarding or alighting	0.000	0.997	0.002
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.997	0.002
V23.1 Passenger injured in nontraffic accident	0.000	0.997	0.002
V23.0 Driver injured in nontraffic accident	0.000	0.997	0.002
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.003	0.997	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.997	0.003
Q04.6 Congenital cerebral cysts	0.002	0.997	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.997	0.003
Z13.6 Special screening examination for cardiovascular disorders	0.003	0.997	0.000
B34.9 Viral infection, unspecified	0.003	0.997	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.002	0.997	0.000
Q03.8 Other congenital hydrocephalus	0.002	0.997	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.002	0.997	0.000
D52 Folate deficiency anaemia	0.000	0.997	0.002
Q83 Congenital malformations of breast	0.002	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.997	0.000
T82.3 Mechanical complication of other vascular grafts	0.000	0.997	0.002
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.997	0.002
Q04.9 Congenital malformation of brain, unspecified	0.002	0.997	0.000
Q04.8 Other specified congenital malformations of brain	0.002	0.997	0.000
Q04.5 Megalencephaly	0.002	0.997	0.000
Q04.4 Septo-optic dysplasia	0.002	0.997	0.000
Q04.3 Other reduction deformities of brain	0.002	0.997	0.000
Q04.2 Holoprosencephaly	0.002	0.997	0.000
Q04.1 Arhinencephaly	0.002	0.997	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
L89.2 Stage III decubitus ulcer	0.000	0.998	0.002
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
N73.0 Acute parametritis and pelvic cellulitis	0.002	0.998	0.000
D53 Other nutritional anaemias	0.000	0.998	0.002
Q00.2 Iniencephaly	0.002	0.998	0.000
Q00.1 Craniorachischisis	0.002	0.998	0.000
Q00.0 Anencephaly	0.002	0.998	0.000
Q01.9 Encephalocele, unspecified	0.002	0.998	0.000
Q01.8 Encephalocele of other sites	0.002	0.998	0.000
Q01.2 Occipital encephalocele	0.002	0.998	0.000
Q01.1 Nasofrontal encephalocele	0.002	0.998	0.000
Q01.0 Frontal encephalocele	0.002	0.998	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.002	0.998	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.002	0.998	0.000
Q06.4 Hydromyelia	0.002	0.998	0.000
Q06.3 Other congenital cauda equina malformations	0.002	0.998	0.000
Q06.2 Diastematomyelia	0.002	0.998	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.002	0.998	0.000
Q06.0 Amyelia	0.002	0.998	0.000
N73 Other female pelvic inflammatory diseases	0.002	0.998	0.000
W13.9 Unspecified place	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.998	0.002
Q54 Hypospadias	0.002	0.998	0.000
N73.5 Female pelvic peritonitis, unspecified	0.002	0.998	0.000
Q83.8 Other congenital malformations of breast	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
H80.9 Otosclerosis, unspecified	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.002	0.998	0.000
I84.1 Internal haemorrhoids with other complications	0.000	0.998	0.002
N73.1 Chronic parametritis and pelvic cellulitis	0.002	0.998	0.000
V23.99 Motorcycle rider injured in collision with car, pick-up truck or van, Unspecified motorcycle rider injured in traffic accident, Unspecified place	0.000	0.998	0.002
C18.0 Caecum	0.002	0.998	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.998	0.002
D52.8 Other folate deficiency anaemias	0.000	0.998	0.002
D52.1 Drug-induced folate deficiency anaemia	0.000	0.998	0.002
D52.0 Dietary folate deficiency anaemia	0.000	0.998	0.002
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
L30.8 Other specified dermatitis	0.000	0.998	0.002
Q83.9 Congenital malformation of breast, unspecified	0.002	0.998	0.000
Q83.3 Accessory nipple	0.002	0.998	0.000
Q83.2 Absent nipple	0.002	0.998	0.000
Q83.0 Congenital absence of breast with absent nipple	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
L89.3 Stage IV decubitus ulcer	0.000	0.998	0.002
Q54.1 Hypospadias, penile	0.002	0.998	0.000
Z93.2 Ileostomy status	0.000	0.998	0.002
M06.34 Rheumatoid nodule (Hand)	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
D53.8 Other specified nutritional anaemias	0.000	0.998	0.002
D53.2 Scorbutic anaemia	0.000	0.998	0.002
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.998	0.002
D53.0 Protein deficiency anaemia	0.000	0.998	0.002
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
N73.8 Other specified female pelvic inflammatory diseases	0.002	0.998	0.000
N73.4 Female chronic pelvic peritonitis	0.002	0.998	0.000
N73.3 Female acute pelvic peritonitis	0.002	0.998	0.000
N73.2 Unspecified parametritis and pelvic cellulitis	0.002	0.998	0.000
B34 Viral infection of unspecified site	0.002	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.998	0.002
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.002	0.998	0.000
D53.9 Nutritional anaemia, unspecified	0.000	0.998	0.002
Q54.8 Other hypospadias	0.002	0.998	0.000
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
N36.2 Urethral caruncle	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.998	0.002
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.002	0.998	0.000
M70.22 Olecranon bursitis-Upper arm	0.000	0.998	0.002
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.998	0.002
I46.9 Cardiac arrest, unspecified	0.000	0.998	0.002
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.002	0.998	0.000
B34.4 Papovirus infection, unspecified	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q11.1 Other anophthalmos	0.002	0.998	0.000
K60 Fissure and fistula of anal and rectal regions	0.002	0.998	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.002	0.998	0.000
B34.8 Other viral infections of unspecified site	0.002	0.998	0.000
K50.1 Crohn's disease of large intestine	0.002	0.998	0.000
N43.3 Hydrocele, unspecified	0.002	0.998	0.000
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
D36.7 Other specified sites	0.002	0.998	0.000
M06.3 Rheumatoid nodule	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
H90 Conductive and sensorineural hearing loss	0.000	0.998	0.002
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
B34.3 Parvovirus infection, unspecified	0.002	0.998	0.000
B34.2 Coronavirus infection, unspecified	0.002	0.998	0.000
B34.1 Enterovirus infection, unspecified	0.002	0.998	0.000
B34.0 Adenovirus infection, unspecified	0.002	0.998	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.998	0.002
Q89.2 Congenital malformations of other endocrine glands	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
D36.0 Lymph nodes	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.001	0.998	0.000
Y83.6 Removal of other organ (partial) (total)	0.002	0.998	0.000
Q53 Undescended testicle	0.001	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.001	0.998	0.000
Q15 Other congenital malformations of eye	0.001	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.001	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.001	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.001	0.998	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.002	0.998	0.000
C15.5 Lower third of oesophagus	0.000	0.998	0.002
Q10.0 Congenital ptosis	0.001	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.001	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.001	0.998	0.000
Q55.6 Other congenital malformations of penis	0.001	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.001	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.001	0.998	0.000
Q55.3 Atresia of vas deferens	0.001	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.001	0.998	0.000
Q55.0 Absence and aplasia of testis	0.001	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.001	0.998	0.000
Q89.8 Other specified congenital malformations	0.001	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.001	0.998	0.000
Q89.4 Conjoined twins	0.001	0.998	0.000
Q89.3 Situs inversus	0.001	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.001	0.998	0.000
Q89.0 Congenital malformations of spleen	0.001	0.998	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.002	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.001	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.001	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.001	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.001	0.998	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.001	0.998	0.000
Q12 Congenital lens malformations	0.001	0.998	0.000
H90-H95 Other disorders of ear	0.000	0.998	0.002
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.998	0.002
B27.9 Infectious mononucleosis, unspecified	0.001	0.998	0.000
Q11.3 Macrophthalmos	0.001	0.998	0.000
Q11.2 Microphthalmos	0.001	0.998	0.000
Q11.0 Cystic eyeball	0.001	0.998	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.001	0.998	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.001	0.998	0.000
Q18 Other congenital malformations of face and neck	0.001	0.998	0.000
K26.4 Chronic or unspecified with haemorrhage	0.002	0.998	0.000
Q80.9 Congenital ichthyosis, unspecified	0.001	0.998	0.000
Q80.8 Other congenital ichthyosis	0.001	0.998	0.000
Q80.4 Harlequin foetus	0.001	0.998	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.001	0.998	0.000
Q80.2 Lamellar ichthyosis	0.001	0.998	0.000
Q80.1 X-linked ichthyosis	0.001	0.998	0.000
Q80.0 Ichthyosis vulgaris	0.001	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.001	0.998	0.000
Q81.8 Other epidermolysis bullosa	0.001	0.998	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.001	0.998	0.000
Q81.1 Epidermolysis bullosa letalis	0.001	0.998	0.000
Q81.0 Epidermolysis bullosa simplex	0.001	0.998	0.000
Q84.9 Congenital malformation of integument, unspecified	0.001	0.998	0.000
Q84.8 Other specified congenital malformations of integument	0.001	0.998	0.000
Q84.6 Other congenital malformations of nails	0.001	0.998	0.000
Q84.5 Enlarged and hypertrophic nails	0.001	0.998	0.000
Q84.4 Congenital leukonychia	0.001	0.998	0.000
Q84.3 Anonychia	0.001	0.998	0.000
Q84.2 Other congenital malformations of hair	0.001	0.998	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.001	0.998	0.000
Q84.0 Congenital alopecia	0.001	0.998	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.001	0.998	0.000
Q86.2 Dysmorphism due to warfarin	0.001	0.998	0.000
Q86.1 Foetal hydantoin syndrome	0.001	0.998	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.001	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.001	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.001	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.001	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.001	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations