TreeWAS – Variant ID: rs2295664

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.999	0.001	0.000
M20-M25 Other joint disorders	0.998	0.002	0.000
M35.3 Polymyalgia rheumatica	0.997	0.003	0.000
M35 Other systemic involvement of connective tissue	0.997	0.003	0.000
M31 Other necrotising vasculopathies	0.995	0.005	0.000
E10.3 With ophthalmic complications	0.993	0.007	0.000
M31.6 Other giant cell arteritis	0.992	0.008	0.000
M45-M49 Spondylopathies	0.990	0.010	0.000
M05 Seropositive rheumatoid arthritis	0.990	0.010	0.000
M45 Ankylosing spondylitis	0.989	0.011	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.987	0.013	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.982	0.018	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.980	0.020	0.000
E10.1 With ketoacidosis	0.977	0.023	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.969	0.031	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.967	0.033	0.000
E10.2 With renal complications	0.944	0.056	0.000
E10.4 With neurological complications	0.943	0.057	0.000
M06.0 Seronegative rheumatoid arthritis	0.930	0.070	0.000
E10.5 With peripheral circulatory complications	0.924	0.076	0.000
M30 Polyarteritis nodosa and related conditions	0.908	0.092	0.000
M06.3 Rheumatoid nodule	0.888	0.112	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.886	0.114	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.861	0.139	0.000
M14 Arthropathies in other diseases classified elsewhere	0.861	0.139	0.000
E10.0 With coma	0.859	0.141	0.000
E10.6 With other specified complications	0.853	0.147	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.853	0.147	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.843	0.157	0.000
M60-M63 Disorders of muscles	0.842	0.158	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.829	0.171	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.807	0.193	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.799	0.201	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.797	0.203	0.000
M12 Other specific arthropathies	0.795	0.205	0.000
M49 Spondylopathies in diseases classified elsewhere	0.794	0.206	0.000
M80-M85 Disorders of bone density and structure	0.789	0.211	0.000
M00-M03 Infectious arthropathies	0.787	0.213	0.000
M07 Psoriatic and enteropathic arthropathies	0.775	0.224	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.775	0.225	0.000
M31.3 Wegener's granulomatosis	0.774	0.225	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.772	0.228	0.000
E10.8 With unspecified complications	0.769	0.231	0.000
M91-M94 Chondropathies	0.766	0.234	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.764	0.236	0.000
M14.6 Neuropathic arthropathy	0.761	0.239	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.759	0.241	0.000
M34 Systemic sclerosis	0.754	0.246	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.750	0.250	0.000
M62 Other disorders of muscle	0.748	0.252	0.000
M30.0 Polyarteritis nodosa	0.744	0.255	0.000
E10-E14 Diabetes mellitus	0.740	0.260	0.000
M95.0 Acquired deformity of nose	0.739	0.261	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.737	0.263	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.731	0.269	0.000
M06.34 Rheumatoid nodule (Hand)	0.728	0.272	0.000
M06.4 Inflammatory polyarthropathy	0.726	0.274	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.724	0.276	0.000
M46 Other inflammatory spondylopathies	0.723	0.277	0.000
E10.7 With multiple complications	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M35.2 Behcet's disease	0.716	0.284	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.715	0.285	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.714	0.285	0.000
M35.8 Other specified systemic involvement of connective tissue	0.714	0.285	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.714	0.285	0.000
M35.5 Multifocal fibrosclerosis	0.714	0.285	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.714	0.285	0.000
M31.9 Necrotising vasculopathy, unspecified	0.713	0.287	0.000
M31.8 Other specified necrotising vasculopathies	0.713	0.287	0.000
M31.7 Microscopic polyangiitis	0.713	0.287	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.713	0.287	0.000
M31.2 Lethal midline granuloma	0.713	0.287	0.000
M31.1 Thrombotic microangiopathy	0.713	0.287	0.000
M31.0 Hypersensitivity angiitis	0.713	0.287	0.000
M05.8 Other seropositive rheumatoid arthritis	0.709	0.290	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.709	0.290	0.000
M05.2 Rheumatoid vasculitis	0.709	0.290	0.000
M05.1 Rheumatoid lung disease	0.709	0.290	0.000
M05.0 Felty's syndrome	0.709	0.290	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.709	0.291	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.709	0.291	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.709	0.291	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.709	0.291	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.709	0.291	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.709	0.291	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.709	0.291	0.000
M24 Other specific joint derangements	0.705	0.295	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.704	0.296	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.704	0.296	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.704	0.296	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.704	0.296	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.704	0.296	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.704	0.296	0.000
M65-M68 Disorders of synovium and tendon	0.703	0.297	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.696	0.303	0.000
M11 Other crystal arthropathies	0.686	0.314	0.000
M86-M90 Other osteopathies	0.671	0.329	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.667	0.333	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.667	0.333	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.667	0.333	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.667	0.333	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.667	0.333	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.667	0.333	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.667	0.333	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.667	0.333	0.000
M62.8 Other specified disorders of muscle	0.664	0.336	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.662	0.338	0.000
M32 Systemic lupus erythematosus	0.654	0.346	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.654	0.346	0.000
M84 Disorders of continuity of bone	0.653	0.347	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.652	0.348	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.651	0.349	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.651	0.349	0.000
M30.2 Juvenile polyarteritis	0.651	0.349	0.000
E14 Unspecified diabetes mellitus	0.647	0.353	0.000
M12.2 Villonodular synovitis (pigmented)	0.643	0.356	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.637	0.363	0.000
M06.38 Rheumatoid nodule (Other)	0.637	0.363	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.637	0.363	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.637	0.363	0.000
M06.33 Rheumatoid nodule (Forearm)	0.637	0.363	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.637	0.363	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.637	0.363	0.000
E11 Non-insulin-dependent diabetes mellitus	0.636	0.364	0.000
M99 Biomechanical lesions, not elsewhere classified	0.636	0.364	0.000
M21 Other acquired deformities of limbs	0.633	0.367	0.000
M24.5 Contracture of joint	0.632	0.368	0.000
M35.7 Hypermobility syndrome	0.632	0.368	0.000
M82 Osteoporosis in diseases classified elsewhere	0.624	0.376	0.000
M02 Reactive arthropathies	0.620	0.380	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.617	0.383	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.617	0.383	0.000
M14.4 Arthropathy in amyloidosis	0.617	0.383	0.000
M14.3 Lipoid dermatoarthritis	0.617	0.383	0.000
M14.2 Diabetic arthropathy	0.617	0.383	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.617	0.383	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.617	0.383	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.617	0.383	0.000
M07.3 Other psoriatic arthropathies	0.615	0.385	0.000
M92 Other juvenile osteochondrosis	0.614	0.386	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.611	0.389	0.000
E11.4 With neurological complications	0.606	0.394	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.604	0.396	0.000
M61 Calcification and ossification of muscle	0.604	0.396	0.000
M34.9 Systemic sclerosis, unspecified	0.594	0.406	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.585	0.414	0.000
M00 Pyogenic arthritis	0.583	0.417	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.577	0.423	0.000
M12.3 Palindromic rheumatism	0.576	0.424	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.571	0.429	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.571	0.429	0.000
M95.5 Acquired deformity of pelvis	0.571	0.429	0.000
M95.4 Acquired deformity of chest and rib	0.571	0.429	0.000
M95.3 Acquired deformity of neck	0.571	0.429	0.000
M95.1 Cauliflower ear	0.571	0.429	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.570	0.430	0.000
M12.5 Traumatic arthropathy	0.570	0.430	0.000
M12.4 Intermittent hydrarthrosis	0.570	0.430	0.000
M12.1 Kaschin-Beck disease	0.570	0.430	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.570	0.430	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.569	0.430	0.000
M49.4 Neuropathic spondylopathy	0.569	0.430	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.569	0.430	0.000
M49.2 Enterobacterial spondylitis	0.569	0.430	0.000
M49.1 Brucella spondylitis	0.569	0.430	0.000
M49.0 Tuberculosis of spine	0.569	0.430	0.000
M35.1 Other overlap syndromes	0.569	0.431	0.000
M83 Adult osteomalacia	0.566	0.434	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.564	0.436	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.564	0.436	0.000
M93 Other osteochondropathies	0.564	0.436	0.000
M60 Myositis	0.560	0.440	0.000
M07.6 Other enteropathic arthropathies	0.556	0.444	0.000
M07.5 Arthropathy in ulcerative colitis	0.556	0.444	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.556	0.444	0.000
M07.2 Psoriatic spondylitis	0.556	0.444	0.000
M07.1 Arthritis mutilans	0.556	0.444	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.556	0.444	0.000
E14.6 With other specified complications	0.556	0.444	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.555	0.445	0.000
M85 Other disorders of bone density and structure	0.554	0.446	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.552	0.448	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.551	0.449	0.000
E11.0 With coma	0.551	0.449	0.000
M24.54 Contracture of joint (Hand)	0.549	0.451	0.000
M84.0 Malunion of fracture	0.548	0.451	0.000
M95.2 Other acquired deformity of head	0.545	0.455	0.000
M81 Osteoporosis without pathological fracture	0.543	0.457	0.000
M24.2 Disorder of ligament	0.542	0.458	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.541	0.459	0.000
M34.0 Progressive systemic sclerosis	0.541	0.459	0.000
M86 Osteomyelitis	0.540	0.460	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.539	0.460	0.000
M34.8 Other forms of systemic sclerosis	0.537	0.463	0.000
M46.0 Spinal enthesopathy	0.537	0.463	0.000
E11.5 With peripheral circulatory complications	0.536	0.464	0.000
M24.7 Protrusio acetabuli	0.536	0.464	0.000
M62.9 Disorder of muscle, unspecified	0.536	0.464	0.000
M62.6 Muscle strain	0.536	0.464	0.000
M62.4 Contracture of muscle	0.536	0.464	0.000
M62.3 Immobility syndrome (paraplegic)	0.536	0.464	0.000
M62.2 Ischaemic infarction of muscle	0.536	0.464	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.536	0.464	0.000
M62.0 Diastasis of muscle	0.536	0.464	0.000
M12.24 Villonodular synovitis (pigmented) (Hand)	0.535	0.465	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.531	0.469	0.000
E12 Malnutrition-related diabetes mellitus	0.530	0.469	0.000
M33 Dermatopolymyositis	0.530	0.470	0.000
M11.9 Crystal arthropathy, unspecified	0.528	0.472	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.527	0.472	0.000
M24.0 Loose body in joint	0.527	0.473	0.000
M34.1 CR(E)ST syndrome	0.526	0.474	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.526	0.474	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.526	0.474	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.525	0.475	0.000
M84.3 Stress fracture, not elsewhere classified	0.525	0.475	0.000
E14.2 Withrenal complications	0.524	0.476	0.000
M67 Other disorders of synovium and tendon	0.524	0.476	0.000
M84.4 Pathological fracture, not elsewhere classified	0.521	0.479	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.521	0.479	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.521	0.479	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.521	0.479	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.521	0.479	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.521	0.479	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.521	0.479	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.521	0.479	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.521	0.479	0.000
M46.8 Other specified inflammatory spondylopathies	0.518	0.481	0.000
M46.5 Other infective spondylopathies	0.518	0.481	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.518	0.481	0.000
M46.2 Osteomyelitis of vertebra	0.518	0.481	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.517	0.483	0.000
E14.5 With peripheral circulatory complications	0.515	0.485	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.514	0.486	0.000
M06.18 Adult-onset Still's disease (Other)	0.514	0.486	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.514	0.486	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.514	0.486	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.514	0.486	0.000
M06.14 Adult-onset Still's disease (Hand)	0.514	0.486	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.514	0.486	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.514	0.486	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.514	0.486	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.514	0.486	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.514	0.486	0.000
M06.28 Rheumatoid bursitis (Other)	0.514	0.486	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.514	0.486	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.514	0.486	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.514	0.486	0.000
M06.24 Rheumatoid bursitis (Hand)	0.514	0.486	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.514	0.486	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.514	0.486	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.514	0.486	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.514	0.486	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.514	0.486	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.514	0.486	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.514	0.486	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.514	0.486	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.514	0.486	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.514	0.486	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.514	0.486	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.514	0.486	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.514	0.486	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.514	0.486	0.000
M08.9 Juvenile arthritis, unspecified	0.514	0.486	0.000
M08.8 Other juvenile arthritis	0.514	0.486	0.000
M08.4 Pauciarticular juvenile arthritis	0.514	0.486	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.514	0.486	0.000
M08.2 Juvenile arthritis with systemic onset	0.514	0.486	0.000
M08.1 Juvenile ankylosing spondylitis	0.514	0.486	0.000
M08.0 Juvenile rheumatoid arthritis	0.514	0.486	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.514	0.486	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.514	0.486	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.514	0.486	0.000
M09.0 Juvenile arthritis in psoriasis	0.514	0.486	0.000
E14.8 With unspecified complications	0.514	0.486	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.513	0.486	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.513	0.487	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.513	0.487	0.000
M36.3 Arthropathy in other blood disorders	0.513	0.487	0.000
M36.2 Haemophilic arthropathy	0.513	0.487	0.000
M36.1 Arthropathy in neoplastic disease	0.513	0.487	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.513	0.487	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.512	0.488	0.000
M65 Synovitis and tenosynovitis	0.512	0.488	0.000
M24.6 Ankylosis of joint	0.512	0.488	0.000
M05.09 Felty's syndrome (Site unspecified)	0.509	0.491	0.000
M05.08 Felty's syndrome (Other)	0.509	0.491	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.509	0.491	0.000
M05.06 Felty's syndrome (Lower leg)	0.509	0.491	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.509	0.491	0.000
M05.04 Felty's syndrome (Hand)	0.509	0.491	0.000
M05.03 Felty's syndrome (Forearm)	0.509	0.491	0.000
M05.02 Felty's syndrome (Upper arm)	0.509	0.491	0.000
M05.01 Felty's syndrome (Shoulder region)	0.509	0.491	0.000
M05.00 Felty's syndrome (Multiple sites)	0.509	0.491	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.509	0.491	0.000
M05.18 Rheumatoid lung disease (Other)	0.509	0.491	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.509	0.491	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.509	0.491	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.509	0.491	0.000
M05.14 Rheumatoid lung disease (Hand)	0.509	0.491	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.509	0.491	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.509	0.491	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.509	0.491	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.509	0.491	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.509	0.491	0.000
M05.28 Rheumatoid vasculitis (Other)	0.509	0.491	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.509	0.491	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.509	0.491	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.509	0.491	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.509	0.491	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.509	0.491	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.509	0.491	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.509	0.491	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.509	0.491	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.509	0.491	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.509	0.491	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.509	0.491	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.509	0.491	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.509	0.491	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.509	0.491	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.509	0.491	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.509	0.491	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.509	0.491	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.509	0.491	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.509	0.491	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.509	0.491	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.509	0.491	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.509	0.491	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.509	0.491	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.509	0.491	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.509	0.491	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.509	0.491	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.509	0.491	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.509	0.491	0.000
M94 Other disorders of cartilage	0.506	0.494	0.000
M24.9 Joint derangement, unspecified	0.506	0.494	0.000
M82.1 Osteoporosis in endocrine disorders	0.505	0.494	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.504	0.496	0.000
M80 Osteoporosis with pathological fracture	0.502	0.498	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.502	0.498	0.000
M02.3 Reiter's disease	0.501	0.499	0.000
M24.57 Contracture of joint (Ankle and foot)	0.501	0.499	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.501	0.499	0.000
M21.7 Unequal limb length (acquired)	0.499	0.501	0.000
E13 Other specified diabetes mellitus	0.498	0.502	0.000
M46.4 Discitis, unspecified	0.495	0.505	0.000
E11.1 With ketoacidosis	0.493	0.507	0.000
M11.8 Other specified crystal arthropathies	0.492	0.508	0.000
M11.1 Familial chondrocalcinosis	0.492	0.508	0.000
M11.0 Hydroxyapatite deposition disease	0.492	0.508	0.000
M84.8 Other disorders of continuity of bone	0.492	0.508	0.000
M21.3 Wrist or foot drop (acquired)	0.490	0.510	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.487	0.513	0.000
M24.56 Contracture of joint (Lower leg)	0.486	0.514	0.000
K90 Intestinal malabsorption	0.000	0.518	0.482
E11.8 With unspecified complications	0.480	0.520	0.000
M89 Other disorders of bone	0.479	0.521	0.000
M21.4 Flat foot [pes planus] (acquired)	0.479	0.521	0.000
M10 Gout	0.478	0.522	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.477	0.522	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.476	0.524	0.000
M62.84 Other specified disorders of muscle (Hand)	0.476	0.524	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.476	0.524	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.474	0.526	0.000
M96.5 Postradiation scoliosis	0.474	0.526	0.000
M96.4 Postsurgical lordosis	0.474	0.526	0.000
M96.3 Postlaminectomy kyphosis	0.474	0.526	0.000
M96.2 Postradiation kyphosis	0.474	0.526	0.000
M62.88 Other specified disorders of muscle (Other)	0.474	0.526	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.471	0.529	0.000
M90 Osteopathies in diseases classified elsewhere	0.470	0.530	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.469	0.531	0.000
M32.8 Other forms of systemic lupus erythematosus	0.469	0.531	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.469	0.531	0.000
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.469	0.531	0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.469	0.531	0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.469	0.531	0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.469	0.531	0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.469	0.531	0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.469	0.531	0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.469	0.531	0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.469	0.531	0.000
M84.9 Disorder of continuity of bone, unspecified	0.468	0.532	0.000
M84.2 Delayed union of fracture	0.468	0.532	0.000
M88 Paget's disease of bone [osteitis deformans]	0.467	0.533	0.000
E14.7 With multiple complications	0.464	0.536	0.000
E14.1 With ketoacidosis	0.464	0.536	0.000
E14.0 With coma	0.464	0.536	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.462	0.538	0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.461	0.538	0.000
M12.28 Villonodular synovitis (pigmented) (Other)	0.461	0.538	0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.461	0.538	0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.461	0.538	0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.461	0.538	0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.461	0.538	0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.461	0.538	0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.461	0.538	0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.461	0.538	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.461	0.539	0.000
M66 Spontaneous rupture of synovium and tendon	0.458	0.542	0.000
M84.03 Malunion of fracture (Forearm)	0.458	0.542	0.000
M24.24 Disorder of ligament (Hand)	0.457	0.543	0.000
E11.7 With multiple complications	0.456	0.544	0.000
M99.9 Biomechanical lesion, unspecified	0.456	0.544	0.000
M99.8 Other biomechanical lesions	0.456	0.544	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.456	0.544	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.456	0.544	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.456	0.544	0.000
M99.4 Connective tissue stenosis of neural canal	0.456	0.544	0.000
M99.3 Osseous stenosis of neural canal	0.456	0.544	0.000
M99.2 Subluxation stenosis of neural canal	0.456	0.544	0.000
M99.1 Subluxation complex (vertebral)	0.456	0.544	0.000
M99.0 Segmental and somatic dysfunction	0.456	0.544	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.455	0.545	0.000
M84.01 Malunion of fracture (Shoulder region)	0.455	0.545	0.000
E14.4 With neurological complications	0.454	0.546	0.000
M21.9 Acquired deformity of limb, unspecified	0.454	0.546	0.000
M21.8 Other specified acquired deformities of limbs	0.454	0.546	0.000
M24.59 Contracture of joint (Site unspecified)	0.453	0.547	0.000
M24.58 Contracture of joint (Other)	0.453	0.547	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.453	0.547	0.000
M24.53 Contracture of joint (Forearm)	0.453	0.547	0.000
M24.52 Contracture of joint (Upper arm)	0.453	0.547	0.000
M24.50 Contracture of joint (Multiple sites)	0.453	0.547	0.000
M93.1 Kienbock's disease of adults	0.448	0.552	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.447	0.552	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.447	0.552	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.447	0.552	0.000
M21.0 Valgus deformity, not elsewhere classified	0.445	0.555	0.000
M02.9 Reactive arthopathy, unspecified	0.445	0.555	0.000
M02.8 Other reactive arthropathies	0.445	0.555	0.000
M02.2 Postimmunisation arthropathy	0.445	0.555	0.000
M02.1 Postdysenteric arthropathy	0.445	0.555	0.000
M02.0 Arthropathy following intestinal bypass	0.445	0.555	0.000
M86.6 Other chronic osteomyelitis	0.443	0.557	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.443	0.557	0.000
M24.51 Contracture of joint (Shoulder region)	0.443	0.557	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.442	0.558	0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.442	0.558	0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.442	0.558	0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.442	0.558	0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.442	0.558	0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.442	0.558	0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.442	0.558	0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.442	0.558	0.000
M07.38 Other psoriatic arthropathies (Other)	0.441	0.559	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.441	0.559	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.441	0.559	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.441	0.559	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.441	0.559	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.441	0.559	0.000
M92.5 Juvenile osteochondrosis of tibia and fibula	0.440	0.560	0.000
M92.1 Juvenile osteochondrosis of radius and ulna	0.440	0.560	0.000
M92.9 Juvenile osteochondrosis, unspecified	0.440	0.560	0.000
M92.8 Other specified juvenile osteochondrosis	0.440	0.560	0.000
M92.4 Juvenile osteochondrosis of patella	0.440	0.560	0.000
M92.3 Other juvenile osteochondrosis of upper limb	0.440	0.560	0.000
M92.2 Juvenile osteochondrosis of hand	0.440	0.560	0.000
M92.0 Juvenile osteochondrosis of humerus	0.440	0.560	0.000
M00.9 Pyogenic arthritis, unspecified	0.437	0.562	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.436	0.563	0.000
M21.6 Other acquired deformities of ankle and foot	0.436	0.564	0.000
M85.6 Other cyst of bone	0.434	0.566	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.433	0.566	0.000
M61.9 Calcification and ossification of muscle, unspecified	0.433	0.567	0.000
M61.5 Other ossification of muscle	0.433	0.567	0.000
M61.4 Other calcification of muscle	0.433	0.567	0.000
M61.3 Calcification and ossification of muscles associated with burns	0.433	0.567	0.000
M61.2 Paralytic calcification and ossification of muscle	0.433	0.567	0.000
M61.1 Myositis ossificans progressiva	0.433	0.567	0.000
M61.0 Myositis ossificans traumatica	0.433	0.567	0.000
M63.8 Other disorders of muscle in diseases classified elsewhere	0.433	0.567	0.000
M63.3 Myositis in sarcoidosis	0.433	0.567	0.000
M63.2 Myositis in other infectious diseases classified elsewhere	0.433	0.567	0.000
M63.1 Myositis in protozoal and parasitic infections classified elsewhere	0.433	0.567	0.000
M63.0 Myositis in bacterial diseases classified elsewhere	0.433	0.567	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.427	0.573	0.000
M35.0 Sicca syndrome [Sjogren]	0.426	0.574	0.000
M24.04 Loose body in joint (Hand)	0.426	0.574	0.000
M48 Other spondylopathies	0.423	0.577	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.422	0.578	0.000
M81.9 Osteoporosis, unspecified	0.421	0.579	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.421	0.579	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.421	0.579	0.000
M12.39 Palindromic rheumatism (Site unspecified)	0.419	0.581	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.418	0.582	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations