TreeWAS – Variant ID: rs2307022

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.645	0.355
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.842	0.158
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.000	0.886	0.113
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.000	0.886	0.113
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.898	0.102
M50.0 Cervical disk disorder with myelopathy	0.000	0.941	0.059
Q61.2 Polycystic kidney, adult type	0.000	0.949	0.051
Q61 Cystic kidney disease	0.000	0.950	0.050
Q61.3 Polycystic kidney, unspecified	0.000	0.952	0.048
G90-G99 Other disorders of the nervous system	0.000	0.954	0.046
G90 Disorders of autonomic nervous system	0.000	0.955	0.045
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.956	0.044
Q61.0 Congenital single renal cyst	0.000	0.958	0.042
Q61.5 Medullary cystic kidney	0.000	0.958	0.042
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.958	0.041
G96 Other disorders of central nervous system	0.000	0.961	0.039
G90.2 Horner's syndrome	0.000	0.962	0.038
Q61.9 Cystic kidney disease, unspecified	0.000	0.962	0.038
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.964	0.036
Q61.8 Other cystic kidney diseases	0.000	0.964	0.036
Q61.1 Polycystic kidney, infantile type	0.000	0.964	0.036
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.965	0.035
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.966	0.034
Q61.4 Renal dysplasia	0.000	0.966	0.034
G90.8 Other disorders of autonomic nervous system	0.000	0.966	0.033
G92 Toxic encephalopathy	0.000	0.966	0.033
G90.4 Autonomic dysreflexia	0.000	0.968	0.032
G90.1 Familial dysautonomia [Riley-Day]	0.000	0.968	0.032
G95 Other diseases of spinal cord	0.000	0.968	0.032
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.970	0.030
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.970	0.030
G90.3 Multisystem degeneration	0.000	0.970	0.029
G96.9 Disorder of central nervous system, unspecified	0.000	0.972	0.028
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.972	0.028
G96.8 Other specified disorders of central nervous system	0.000	0.972	0.028
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.974	0.026
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.974	0.026
G97.8 Other postprocedural disorders of nervous system	0.000	0.974	0.026
G95.8 Other specified diseases of spinal cord	0.000	0.974	0.026
G96.0 Cerebrospinal fluid leak	0.000	0.975	0.025
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.976	0.024
G95.0 Syringomyelia and syringobulbia	0.000	0.977	0.023
G95.1 Vascular myelopathies	0.000	0.977	0.023
G95.9 Disease of spinal cord, unspecified	0.000	0.977	0.023
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.000	0.978	0.022
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.000	0.978	0.022
G94.1 Hydrocephalus in neoplastic disease	0.000	0.979	0.021
G94.2 Hydrocephalus in other diseases classified elsewhere	0.000	0.980	0.020
S02.4 Fracture of malar and maxillary bones	0.000	0.983	0.017
G95.2 Cord compression, unspecified	0.000	0.985	0.015
Q60-Q64 Congenital malformations of the urinary system	0.000	0.987	0.013
L53.9 Erythematous condition, unspecified	0.000	0.988	0.012
G91 Hydrocephalus	0.000	0.989	0.011
N81.5 Vaginal enterocele	0.011	0.989	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.990	0.010
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.990	0.010
K14.0 Glossitis	0.009	0.991	0.000
Q64 Other congenital malformations of urinary system	0.000	0.991	0.009
K60.2 Anal fissure, unspecified	0.000	0.991	0.009
G91.8 Other hydrocephalus	0.000	0.992	0.008
Q62.5 Duplication of ureter	0.000	0.992	0.008
T87.6 Other and unspecified complications of amputation stump	0.008	0.992	0.000
T87.4 Infection of amputation stump	0.008	0.992	0.000
R10.0 Acute abdomen	0.007	0.993	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.993	0.007
Q62.1 Atresia and stenosis of ureter	0.000	0.993	0.007
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.993	0.007
Q62.8 Other congenital malformations of ureter	0.000	0.993	0.007
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.993	0.007
Q62.6 Malposition of ureter	0.000	0.993	0.007
Q62.4 Agenesis of ureter	0.000	0.993	0.007
Q62.0 Congenital hydronephrosis	0.000	0.993	0.007
G91.0 Communicating hydrocephalus	0.000	0.993	0.007
Q63 Other congenital malformations of kidney	0.000	0.993	0.007
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.993	0.007
M81.99 Osteoporosis, unspecified (Site unspecified)	0.007	0.993	0.000
G91.2 Normal-pressure hydrocephalus	0.000	0.993	0.007
Z98.8 Other specified postsurgical states	0.000	0.993	0.007
Q62.2 Congenital megaloureter	0.000	0.993	0.007
T87 Complications peculiar to reattachment and amputation	0.007	0.993	0.000
Q64.4 Malformation of urachus	0.000	0.993	0.007
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.993	0.006
Q64.8 Other specified congenital malformations of urinary system	0.000	0.993	0.006
Q64.6 Congenital diverticulum of bladder	0.000	0.993	0.006
Q64.5 Congenital absence of bladder and urethra	0.000	0.993	0.006
Q64.2 Congenital posterior urethral valves	0.000	0.993	0.006
Q64.1 Exstrophy of urinary bladder	0.000	0.993	0.006
Q64.0 Epispadias	0.000	0.993	0.006
M81.9 Osteoporosis, unspecified	0.007	0.993	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.994	0.006
K60.0 Acute anal fissure	0.000	0.994	0.006
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.994	0.006
K60 Fissure and fistula of anal and rectal regions	0.000	0.994	0.006
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.006	0.994	0.000
K60.5 Anorectal fistula	0.000	0.994	0.006
Q60.3 Renal hypoplasia, unilateral	0.000	0.994	0.006
G91.9 Hydrocephalus, unspecified	0.000	0.994	0.006
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.006	0.994	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.006	0.994	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.005	0.994	0.000
G91.1 Obstructive hydrocephalus	0.000	0.994	0.005
Q60.6 Potter's syndrome	0.000	0.994	0.005
Q60.5 Renal hypoplasia, unspecified	0.000	0.994	0.005
Q60.4 Renal hypoplasia, bilateral	0.000	0.994	0.005
Q60.1 Renal agenesis, bilateral	0.000	0.994	0.005
M81 Osteoporosis without pathological fracture	0.006	0.994	0.000
Q63.3 Hyperplastic and giant kidney	0.000	0.995	0.005
Q63.2 Ectopic kidney	0.000	0.995	0.005
M81.96 Osteoporosis, unspecified (Lower leg)	0.005	0.995	0.000
T87.3 Neuroma of amputation stump	0.005	0.995	0.000
Q63.0 Accessory kidney	0.000	0.995	0.005
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.995	0.005
G60.0 Hereditary motor and sensory neuropathy	0.005	0.995	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.005	0.995	0.000
Q63.8 Other specified congenital malformations of kidney	0.000	0.995	0.005
T87.2 Complications of other reattached body part	0.005	0.995	0.000
T87.1 Complications of reattached (part of) lower extremity	0.005	0.995	0.000
T87.0 Complications of reattached (part of) upper extremity	0.005	0.995	0.000
M81.2 Osteoporosis of disuse	0.005	0.995	0.000
M81.4 Drug-induced osteoporosis	0.005	0.995	0.000
T87.5 Necrosis of amputation stump	0.005	0.995	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.005	0.995	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.005	0.995	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.005	0.995	0.000
M81.0 Postmenopausal osteoporosis	0.005	0.995	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.995	0.005
K14 Diseases of tongue	0.005	0.995	0.000
Q60.2 Renal agenesis, unspecified	0.000	0.995	0.004
G60.8 Other hereditary and idiopathic neuropathies	0.005	0.995	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.995	0.004
M81.94 Osteoporosis, unspecified (Hand)	0.004	0.995	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.000	0.995	0.005
K60.1 Chronic anal fissure	0.000	0.996	0.004
M81.1 Postoophorectomy osteoporosis	0.004	0.996	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.004	0.996	0.000
K60.4 Rectal fistula	0.000	0.996	0.004
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.996	0.004
I30.9 Acute pericarditis, unspecified	0.004	0.996	0.000
M50 Cervical disk disorders	0.000	0.996	0.004
Q60.0 Renal agenesis, unilateral	0.000	0.996	0.004
M81.6 Localised osteoporosis [Lequesne]	0.004	0.996	0.000
M81.5 Idiopathic osteoporosis	0.004	0.996	0.000
K14.6 Glossodynia	0.004	0.996	0.000
G60 Hereditary and idiopathic neuropathy	0.004	0.996	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.996	0.004
M81.3 Postsurgical malabsorption osteoporosis	0.004	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
S02.8 Fractures of other skull and facial bones	0.000	0.996	0.004
K14.3 Hypertrophy of tongue papillae	0.004	0.996	0.000
M50.8 Other cervical disk disorders	0.000	0.996	0.004
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.004	0.996	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.004	0.996	0.000
M81.28 Osteoporosis of disuse (Other)	0.004	0.996	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.004	0.996	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.004	0.996	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.004	0.996	0.000
M81.24 Osteoporosis of disuse (Hand)	0.004	0.996	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.004	0.996	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.004	0.996	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.004	0.996	0.000
K14.8 Other diseases of tongue	0.004	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.004	0.996	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.996	0.004
K14.2 Median rhomboid glossitis	0.004	0.996	0.000
M81.8 Other osteoporosis	0.004	0.996	0.000
M81.48 Drug-induced osteoporosis (Other)	0.004	0.996	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.004	0.996	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.004	0.996	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.004	0.996	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.004	0.996	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.004	0.996	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.004	0.996	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.004	0.996	0.000
L53 Other erythematous conditions	0.000	0.996	0.004
S02 Fracture of skull and facial bones	0.000	0.996	0.004
M81.08 Postmenopausal osteoporosis (Other)	0.004	0.996	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.004	0.996	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.004	0.996	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.004	0.996	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.004	0.996	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.004	0.996	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.004	0.996	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.004	0.996	0.000
G25.3 Myoclonus	0.000	0.996	0.004
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
O26.9 Pregnancy-related condition, unspecified	0.004	0.996	0.000
Q82.5 Congenital nonneoplastic naevus	0.000	0.996	0.004
G25 Other extrapyramidal and movement disorders	0.000	0.996	0.004
K14.5 Plicated tongue	0.004	0.996	0.000
K14.4 Atrophy of tongue papillae	0.004	0.996	0.000
F31 Bipolar affective disorder	0.000	0.996	0.004
M81.49 Drug-induced osteoporosis (Site unspecified)	0.003	0.996	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.996	0.004
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.003	0.996	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.003	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.003	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.003	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.003	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.003	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.003	0.997	0.000
M23.8 Other internal derangements of knee	0.000	0.997	0.003
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.997	0.003
M81.59 Idiopathic osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.003	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.003	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.003	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.003	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.003	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.003	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.003	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.003	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.003	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.003	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.003	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.003	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.003	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.003	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.003	0.997	0.000
F17.2 Dependence syndrome	0.003	0.997	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.997	0.003
F31.9 Bipolar affective disorder, unspecified	0.000	0.997	0.003
Q82 Other congenital malformations of skin	0.000	0.997	0.003
G60.3 Idiopathic progressive neuropathy	0.003	0.997	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.003	0.997	0.000
G60.1 Refsum's disease	0.003	0.997	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.997	0.003
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.997	0.003
G25.2 Other specified forms of tremor	0.000	0.997	0.003
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.997	0.003
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.003	0.997	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.997	0.003
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.003
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.003	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.003	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.003	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.003	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.003	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.003	0.997	0.000
S02.81 Fractures of other skull and facial bones (open)	0.000	0.997	0.003
F31.8 Other bipolar affective disorders	0.000	0.997	0.003
G25.1 Drug-induced tremor	0.000	0.997	0.003
S02.6 Fracture of mandible	0.000	0.997	0.003
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
Q82.2 Mastocytosis	0.000	0.997	0.003
K14.1 Geographic tongue	0.003	0.997	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
T46.7 Peripheral vasodilators	0.003	0.997	0.000
M81.89 Other osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.88 Other osteoporosis (Other)	0.003	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.003	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.003	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.003	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.003	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.003	0.997	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.997	0.003
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.997	0.003
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
L53.3 Other chronic figurate erythema	0.000	0.997	0.003
L53.2 Erythema marginatum	0.000	0.997	0.003
L53.1 Erythema annulare centrifugum	0.000	0.997	0.003
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.003	0.997	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
K56.0 Paralytic ileus	0.000	0.997	0.003
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.997	0.003
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.997	0.003
G25.4 Drug-induced chorea	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
L53.0 Toxic erythema	0.000	0.997	0.003
T36.0 Penicillins	0.003	0.997	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.000	0.997	0.003
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
J02.9 Acute pharyngitis, unspecified	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.000	0.997	0.003
M81.80 Other osteoporosis (Multiple sites)	0.002	0.997	0.000
J92.0 Pleural plaque with presence of asbestos	0.003	0.997	0.000
Q82.0 Hereditary lymphoedema	0.000	0.997	0.003
S02.7 Multiple fractures involving skull and facial bones	0.000	0.997	0.003
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.997	0.003
K56.1 Intussusception	0.000	0.997	0.003
O67.9 Intrapartum haemorrhage, unspecified	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
Q82.9 Congenital malformation of skin, unspecified	0.000	0.997	0.002
Q82.4 Ectodermal dysplasia (anhidrotic)	0.000	0.997	0.002
Q82.3 Incontinentia pigmenti	0.000	0.997	0.002
Q82.1 Xeroderma pigmentosum	0.000	0.997	0.002
K14.9 Disease of tongue, unspecified	0.003	0.997	0.000
K60.3 Anal fistula	0.000	0.997	0.003
S02.60 Fracture of mandible (closed)	0.000	0.997	0.003
T36.4 Tetracyclines	0.003	0.997	0.000
G25.5 Other chorea	0.000	0.997	0.002
M50.3 Other cervical disk degeneration	0.000	0.997	0.003
Q80-Q89 Other congenital malformations	0.000	0.997	0.003
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.997	0.002
Q85.8 Other phakomatoses, not elsewhere classified	0.000	0.997	0.003
T38.5 Other oestrogens and progestogens	0.002	0.997	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.002
G25.0 Essential tremor	0.000	0.997	0.003
T38.1 Thyroid hormones and substitutes	0.002	0.997	0.000
S02.61 Fracture of mandible (open)	0.000	0.997	0.002
K56.2 Volvulus	0.000	0.997	0.003
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.997	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.002
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.997	0.002
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.997	0.002
L53.8 Other specified erythematous conditions	0.000	0.997	0.002
M50.9 Cervical disk disorder, unspecified	0.000	0.997	0.002
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.997	0.002
T46.1 Calcium-channel blockers	0.002	0.997	0.000
B91 Sequelae of poliomyelitis	0.000	0.997	0.002
S02.0 Fracture of vault of skull	0.000	0.998	0.002
N90.4 Leukoplakia of vulva	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.000	0.998	0.002
K56.4 Other impaction of intestine	0.000	0.998	0.002
Q44.6 Cystic disease of liver	0.000	0.998	0.002
S02.5 Fracture of tooth	0.000	0.998	0.002
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.998	0.002
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.000	0.998	0.002
S02.2 Fracture of nasal bones	0.000	0.998	0.002
T85.2 Mechanical complication of intraocular lens	0.000	0.998	0.002
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
S02.31 Fracture of orbital floor (open)	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.002	0.998	0.000
K56.7 Ileus, unspecified	0.000	0.998	0.002
T36.3 Macrolides	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.000	0.998	0.002
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.998	0.002
Q83 Congenital malformations of breast	0.000	0.998	0.002
T36.8 Other systemic antibiotics	0.002	0.998	0.000
I30 Acute pericarditis	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.000	0.998	0.002
Q84 Other congenital malformations of integument	0.000	0.998	0.002
Q81 Epidermolysis bullosa	0.000	0.998	0.002
G93 Other disorders of brain	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
K38.1 Appendicular concretions	0.002	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.000	0.998	0.002
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.000	0.998	0.002
M77.1 Lateral epicondylitis	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.000	0.998	0.002
T42.0 Hydantoin derivatives	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
Q80 Congenital ichthyosis	0.000	0.998	0.002
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Q83.8 Other congenital malformations of breast	0.000	0.998	0.002
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.000	0.998	0.002
Q00-Q07 Congenital malformations of the nervous system	0.000	0.998	0.002
S02.51 Fracture of tooth (open)	0.000	0.998	0.002
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
S02.30 Fracture of orbital floor (closed)	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
I30.1 Infective pericarditis	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.000	0.998	0.002
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
T42.3 Barbiturates	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
G20-G26 Extrapyramidal and movement disorders	0.000	0.998	0.002
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.998	0.002
G93.5 Compression of brain	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
Q07 Other congenital malformations of nervous system	0.000	0.998	0.002
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.000	0.998	0.002
F30.0 Hypomania	0.000	0.998	0.002
I30.8 Other forms of acute pericarditis	0.002	0.998	0.000
Q83.9 Congenital malformation of breast, unspecified	0.000	0.998	0.002
Q83.2 Absent nipple	0.000	0.998	0.002
Q83.0 Congenital absence of breast with absent nipple	0.000	0.998	0.002
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.002	0.998	0.000
M77.13 Lateral epicondylitis-Forearm	0.000	0.998	0.002
G40.8 Other epilepsy	0.000	0.998	0.002
I30.0 Acute nonspecific idiopathic pericarditis	0.002	0.998	0.000
Q07.8 Other specified congenital malformations of nervous system	0.000	0.998	0.002
Q83.1 Accessory breast	0.000	0.998	0.002
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.000	0.998	0.002
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.998	0.002
S02.01 Fracture of vault of skull (open)	0.000	0.998	0.001
Q85.1 Tuberous sclerosis	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.000	0.998	0.002
G93.9 Disorder of brain, unspecified	0.000	0.998	0.002
G93.7 Reye's syndrome	0.000	0.998	0.002
K56.3 Gallstone ileus	0.000	0.998	0.002
Q44.4 Choledochal cyst	0.000	0.998	0.002
Q81.9 Epidermolysis bullosa, unspecified	0.000	0.998	0.002
Q81.8 Other epidermolysis bullosa	0.000	0.998	0.002
Q81.2 Epidermolysis bullosa dystrophica	0.000	0.998	0.002
Q81.1 Epidermolysis bullosa letalis	0.000	0.998	0.002
Q81.0 Epidermolysis bullosa simplex	0.000	0.998	0.002
Q84.9 Congenital malformation of integument, unspecified	0.000	0.998	0.002
Q84.8 Other specified congenital malformations of integument	0.000	0.998	0.002
Q84.6 Other congenital malformations of nails	0.000	0.998	0.002
Q84.5 Enlarged and hypertrophic nails	0.000	0.998	0.002
Q84.4 Congenital leukonychia	0.000	0.998	0.002
Q84.3 Anonychia	0.000	0.998	0.002
Q84.2 Other congenital malformations of hair	0.000	0.998	0.002
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.000	0.998	0.002
Q84.0 Congenital alopecia	0.000	0.998	0.002
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.000	0.998	0.002
Q86.2 Dysmorphism due to warfarin	0.000	0.998	0.002
Q86.1 Foetal hydantoin syndrome	0.000	0.998	0.002
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
Q05 Spina bifida	0.000	0.998	0.002
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.000	0.998	0.002
Q87.3 Congenital malformation syndromes involving early overgrowth	0.000	0.998	0.002
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.000	0.998	0.002
M77.19 Lateral epicondylitis (Site unspecified)	0.000	0.998	0.002
M77.18 Lateral epicondylitis-Other	0.000	0.998	0.002
M77.17 Lateral epicondylitis-Ankle/Foot	0.000	0.998	0.002
M77.16 Lateral epicondylitis (Lower leg)	0.000	0.998	0.002
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.000	0.998	0.002
M77.14 Lateral epicondylitis-Hand	0.000	0.998	0.002
M77.11 Lateral epicondylitis-Shldr region	0.000	0.998	0.002
M77.10 Lateral epicondylitis (Multiple sites)	0.000	0.998	0.002
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
T42.1 Iminostilbenes	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.000	0.998	0.002
Q80.8 Other congenital ichthyosis	0.000	0.998	0.002
Q80.4 Harlequin foetus	0.000	0.998	0.002
Q80.3 Congenital bullous ichthyosiform erythroderma	0.000	0.998	0.002
Q80.2 Lamellar ichthyosis	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations