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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2394403
log Bayes Factor = 65.7521
Chromosome 6   position 30,767,869  (GRCh37) Explore rs2394403 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.008 0.992
E50-E64 Other nutritional deficiencies
0.000 0.010 0.990
L40.0 Psoriasis vulgaris
0.981 0.019 0.000
E53 Deficiency of other B group vitamins
0.000 0.020 0.980
E10.3 With ophthalmic complications
0.000 0.024 0.976
E53.8 Deficiency of other specified B group vitamins
0.000 0.027 0.973
E10.4 With neurological complications
0.000 0.030 0.970
T36-T50 Poisoning by drugs, medicaments and biological substances
0.965 0.035 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.962 0.038 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.950 0.050 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.944 0.056 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.933 0.067 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.933 0.067 0.000
E10.5 With peripheral circulatory complications
0.000 0.068 0.932
T43.2 Other and unspecified antidepressants
0.925 0.075 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.920 0.080 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.884 0.116 0.000
L40.1 Generalised pustular psoriasis
0.875 0.125 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.873 0.127 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.861 0.139 0.000
E55 Vitamin D deficiency
0.000 0.164 0.835
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.834 0.166 0.000
E06 Thyroiditis
0.000 0.177 0.823
E10.2 With renal complications
0.000 0.185 0.815
T42.4 Benzodiazepines
0.811 0.189 0.000
E10.8 With unspecified complications
0.000 0.191 0.809
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.192 0.808
E10.6 With other specified complications
0.000 0.208 0.792
T43.4 Butyrophenone and thioxanthene neuroleptics
0.791 0.209 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.791 0.209 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.778 0.222 0.000
E10.0 With coma
0.000 0.236 0.763
T43.6 Psychostimulants with abuse potential
0.749 0.251 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.743 0.257 0.000
L40.8 Other psoriasis
0.739 0.261 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.733 0.267 0.000
E06.3 Autoimmune thyroiditis
0.000 0.275 0.725
E55.9 Vitamin D deficiency, unspecified
0.000 0.275 0.725
E10.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E04 Other non-toxic goitre
0.000 0.287 0.713
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.290 0.710
E63 Other nutritional deficiencies
0.000 0.290 0.710
E56 Other vitamin deficiencies
0.000 0.290 0.710
E51 Thiamine deficiency
0.000 0.290 0.710
E50 Vitamin A deficiency
0.000 0.290 0.710
E60 Dietary zinc deficiency
0.000 0.290 0.710
E59 Dietary selenium deficiency
0.000 0.290 0.710
E58 Dietary calcium deficiency
0.000 0.290 0.710
E54 Ascorbic acid deficiency
0.000 0.290 0.710
E52 Niacin deficiency [pellagra]
0.000 0.290 0.710
E07 Other disorders of thyroid
0.000 0.292 0.708
E10.1 With ketoacidosis
0.000 0.293 0.707
E53.9 Vitamin B deficiency, unspecified
0.000 0.297 0.702
E53.1 Pyridoxine deficiency
0.000 0.297 0.702
E53.0 Riboflavin deficiency
0.000 0.297 0.702
T36 Poisoning by systemic antibiotics
0.700 0.300 0.000
T39.1 4-Aminophenol derivatives
0.692 0.308 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.692 0.308 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.692 0.308 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.692 0.308 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.692 0.308 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.309 0.691
T43.9 Psychotropic drug, unspecified
0.690 0.310 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.690 0.310 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.690 0.310 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.690 0.310 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.681 0.319 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.681 0.319 0.000
T42.3 Barbiturates
0.681 0.319 0.000
T42.2 Succinimides and oxazolidinediones
0.681 0.319 0.000
T42.0 Hydantoin derivatives
0.681 0.319 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.680 0.320 0.000
T50.8 Diagnostic agents
0.677 0.323 0.000
T50.7 Analeptics and opioid receptor antagonists
0.677 0.323 0.000
T50.5 Appetite depressants
0.677 0.323 0.000
T50.4 Drugs affecting uric acid metabolism
0.677 0.323 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.677 0.323 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.677 0.323 0.000
T50.1 Loop [high-ceiling] diuretics
0.677 0.323 0.000
T50.0 Mineralocorticoids and their antagonists
0.677 0.323 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.329 0.671
E04.9 Non-toxic goitre, unspecified
0.000 0.329 0.671
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.669 0.331 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.669 0.331 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.669 0.331 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.669 0.331 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.669 0.331 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.669 0.331 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.669 0.331 0.000
T44.0 Anticholinesterase agents
0.669 0.331 0.000
E61 Deficiency of other nutrient elements
0.000 0.335 0.665
T47.0 Histamine H(2)-receptor antagonists
0.662 0.338 0.000
E13 Other specified diabetes mellitus
0.000 0.340 0.660
T43.5 Other and unspecified antipsychotics and neuroleptics
0.654 0.346 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.361 0.638
E40-E46 Malnutrition
0.000 0.371 0.629
M07.30 Other psoriatic arthropathies (Multiple sites)
0.624 0.376 0.000
M07.3 Other psoriatic arthropathies
0.619 0.381 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.612 0.388 0.000
T42.1 Iminostilbenes
0.610 0.390 0.000
E03.8 Other specified hypothyroidism
0.000 0.394 0.606
E55.0 Rickets, active
0.000 0.401 0.599
E07.9 Disorder of thyroid, unspecified
0.000 0.406 0.594
E06.5 Other chronic thyroiditis
0.000 0.410 0.590
E06.4 Drug-induced thyroiditis
0.000 0.410 0.590
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.410 0.590
E06.1 Subacute thyroiditis
0.000 0.410 0.590
E06.0 Acute thyroiditis
0.000 0.410 0.590
T46.4 Angiotensin-converting-enzyme inhibitors
0.588 0.412 0.000
T39.0 Salicylates
0.582 0.418 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.421 0.579
T47.1 Other antacids and anti-gastric-secretion drugs
0.574 0.426 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.567 0.433 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.567 0.433 0.000
T47.7 Emetics
0.567 0.433 0.000
T47.6 Antidiarrhoeal drugs
0.567 0.433 0.000
T47.5 Digestants
0.567 0.433 0.000
T47.4 Other laxatives
0.567 0.433 0.000
T47.3 Saline and osmotic laxatives
0.567 0.433 0.000
T47.2 Stimulant laxatives
0.567 0.433 0.000
K90 Intestinal malabsorption
0.000 0.433 0.567
T45.0 Antiallergic and antiemetic drugs
0.562 0.437 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.450 0.550
T38.1 Thyroid hormones and substitutes
0.541 0.459 0.000
T39.4 Antirheumatics, not elsewhere classified
0.533 0.467 0.000
T39.2 Pyrazolone derivatives
0.533 0.467 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.528 0.472 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.525 0.475 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.525 0.475 0.000
T46.7 Peripheral vasodilators
0.525 0.475 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.525 0.475 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.525 0.475 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.525 0.475 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.525 0.475 0.000
E06.9 Thyroiditis, unspecified
0.000 0.480 0.520
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.480 0.519
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.483 0.516
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.515 0.485 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.515 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
T38.9 Other and unspecified hormone antagonists
0.513 0.487 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.513 0.487 0.000
T38.7 Androgens and anabolic congeners
0.513 0.487 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.513 0.487 0.000
T38.5 Other oestrogens and progestogens
0.513 0.487 0.000
T38.4 Oral contraceptives
0.513 0.487 0.000
T38.2 Antithyroid drugs
0.513 0.487 0.000
T38.0 Glucocorticoids and synthetic analogues
0.513 0.487 0.000
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E04.8 Other specified non-toxic goitre
0.000 0.489 0.511
T36.0 Penicillins
0.510 0.490 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.491 0.509
E50.8 Other manifestations of vitamin A deficiency
0.000 0.491 0.509
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.491 0.509
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.491 0.509
E50.5 Vitamin A deficiency with night blindness
0.000 0.491 0.509
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.491 0.509
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.491 0.509
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.491 0.509
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.491 0.509
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.491 0.509
E51.9 Thiamine deficiency, unspecified
0.000 0.491 0.509
E51.8 Other manifestations of thiamine deficiency
0.000 0.491 0.509
E51.2 Wernicke's encephalopathy
0.000 0.491 0.509
E51.1 Beriberi
0.000 0.491 0.509
E56.9 Vitamin deficiency, unspecified
0.000 0.491 0.509
E56.8 Deficiency of other vitamins
0.000 0.491 0.509
E56.1 Deficiency of vitamin K
0.000 0.491 0.509
E56.0 Deficiency of vitamin E
0.000 0.491 0.509
E63.9 Nutritional deficiency, unspecified
0.000 0.491 0.509
E63.8 Other specified nutritional deficiencies
0.000 0.491 0.509
E63.1 Imbalance of constituents of food intake
0.000 0.491 0.509
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.491 0.509
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.491 0.509
E64.8 Sequelae of other nutritional deficiencies
0.000 0.491 0.509
E64.3 Sequelae of rickets
0.000 0.491 0.509
E64.2 Sequelae of vitamin C deficiency
0.000 0.491 0.509
E64.1 Sequelae of vitamin A deficiency
0.000 0.491 0.509
E64.0 Sequelae of protein-energy malnutrition
0.000 0.491 0.509
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.508 0.492 0.000
E07.1 Dyshormogenetic goitre
0.000 0.492 0.507
E07.0 Hypersecretion of calcitonin
0.000 0.492 0.507
M07.34 Other psoriatic arthropathies (Hand)
0.507 0.493 0.000
T46.1 Calcium-channel blockers
0.505 0.495 0.000
T36.9 Systemic antibiotic, unspecified
0.502 0.498 0.000
T36.8 Other systemic antibiotics
0.502 0.498 0.000
T36.7 Antifungal antibiotics, systemically used
0.502 0.498 0.000
T36.6 Rifamycins
0.502 0.498 0.000
T36.5 Aminoglycosides
0.502 0.498 0.000
T36.4 Tetracyclines
0.502 0.498 0.000
T36.3 Macrolides
0.502 0.498 0.000
T36.2 Chloramphenicol group
0.502 0.498 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.502 0.498 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.500 0.500
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.496 0.504 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.496 0.504 0.000
T37.5 Antiviral drugs
0.496 0.504 0.000
T37.4 Anthelminthics
0.496 0.504 0.000
T37.3 Other antiprotozoal drugs
0.496 0.504 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.496 0.504 0.000
T37.1 Antimycobacterial drugs
0.496 0.504 0.000
T37.0 Sulphonamides
0.496 0.504 0.000
T41.5 Therapeutic gases
0.496 0.504 0.000
T41.4 Anaesthetic, unspecified
0.496 0.504 0.000
T41.3 Local anaesthetics
0.496 0.504 0.000
T41.2 Other and unspecified general anaesthetics
0.496 0.504 0.000
T41.1 Intravenous anaesthetics
0.496 0.504 0.000
T41.0 Inhaled anaesthetics
0.496 0.504 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.496 0.504 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.496 0.504 0.000
T48.5 Anti-common-cold drugs
0.496 0.504 0.000
T48.4 Expectorants
0.496 0.504 0.000
T48.3 Antitussives
0.496 0.504 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.496 0.504 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.496 0.504 0.000
T48.0 Oxytocic drugs
0.496 0.504 0.000
T49.9 Topical agent, unspecified
0.496 0.504 0.000
T49.8 Other topical agents
0.496 0.504 0.000
T49.7 Dental drugs, topically applied
0.496 0.504 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.496 0.504 0.000
T49.5 Ophthalmological drugs and preparations
0.496 0.504 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.496 0.504 0.000
T49.3 Emollients, demulcents and protectants
0.496 0.504 0.000
T49.2 Local astringents and local detergents
0.496 0.504 0.000
T49.1 Antipruritics
0.496 0.504 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.496 0.504 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.509 0.491
T45.9 Primarily systemic and haematological agent, unspecified
0.487 0.512 0.000
T45.8 Other primarily systemic and haematological agents
0.487 0.512 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.487 0.512 0.000
T45.6 Fibrinolysis-affecting drugs
0.487 0.512 0.000
T45.4 Iron and its compounds
0.487 0.512 0.000
T45.3 Enzymes, not elsewhere classified
0.487 0.512 0.000
T45.2 Vitamins, not elsewhere classified
0.487 0.512 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.519 0.481
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.519 0.481
E16.4 Abnormal secretion of gastrin
0.000 0.519 0.481
E16.3 Increased secretion of glucagon
0.000 0.519 0.481
E16.1 Other hypoglycaemia
0.000 0.523 0.477
E61.9 Deficiency of nutrient element, unspecified
0.000 0.523 0.477
E61.8 Deficiency of other specified nutrient elements
0.000 0.523 0.477
E61.7 Deficiency of multiple nutrient elements
0.000 0.523 0.477
E61.6 Vanadium deficiency
0.000 0.523 0.477
E61.5 Molybdenum deficiency
0.000 0.523 0.477
E61.4 Chromium deficiency
0.000 0.523 0.477
E61.3 Manganese deficiency
0.000 0.523 0.477
E61.2 Magnesium deficiency
0.000 0.523 0.477
E61.0 Copper deficiency
0.000 0.523 0.477
E13.8 With unspecified complications
0.000 0.526 0.473
E13.7 With multiple complications
0.000 0.526 0.473
E13.6 With other specified complications
0.000 0.526 0.473
E13.5 With peripheral circulatory complications
0.000 0.526 0.473
E13.4 With neurological complications
0.000 0.526 0.473
E13.3 With ophthalmic complications
0.000 0.526 0.473
E13.2 With renal complications
0.000 0.526 0.473
E13.1 With ketoacidosis
0.000 0.526 0.473
E13.0 With coma
0.000 0.526 0.473
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.473 0.527 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.457 0.542 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.546 0.454
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.549 0.451
E45 Retarded development following protein-energy malnutrition
0.000 0.549 0.451
E43 Unspecified severe protein-energy malnutrition
0.000 0.549 0.451
E42 Marasmic kwashiorkor
0.000 0.549 0.451
E41 Nutritional marasmus
0.000 0.549 0.451
E40 Kwashiorkor
0.000 0.549 0.451
M07.38 Other psoriatic arthropathies (Other)
0.444 0.556 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.444 0.556 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.444 0.556 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.444 0.556 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.444 0.556 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.435 0.564 0.000
E61.1 Iron deficiency
0.000 0.568 0.432
E13.9 Without complications
0.000 0.582 0.418
K90.3 Pancreatic steatorrhoea
0.000 0.593 0.407
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.593 0.407
K90.1 Tropical sprue
0.000 0.593 0.407
E14 Unspecified diabetes mellitus
0.000 0.604 0.395
T45.5 Anticoagulants
0.390 0.609 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.610 0.390
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.616 0.383
K90.8 Other intestinal malabsorption
0.000 0.627 0.373
E46 Unspecified protein-energy malnutrition
0.000 0.635 0.364
E67 Other hyperalimentation
0.000 0.648 0.352
E68 Sequelae of hyperalimentation
0.000 0.648 0.352
E07.8 Other specified disorders of thyroid
0.001 0.660 0.339
E44.1 Mild protein-energy malnutrition
0.000 0.676 0.324
E44.0 Moderate protein-energy malnutrition
0.000 0.676 0.324
E14.3 With ophthalmic complications
0.000 0.698 0.302
E14.8 With unspecified complications
0.000 0.716 0.284
E14.7 With multiple complications
0.000 0.716 0.284
E14.6 With other specified complications
0.000 0.716 0.284
E14.2 Withrenal complications
0.000 0.716 0.284
E14.0 With coma
0.000 0.716 0.284
E20-E35 Disorders of other endocrine glands
0.000 0.725 0.275
M07 Psoriatic and enteropathic arthropathies
0.269 0.728 0.004
E14.4 With neurological complications
0.000 0.728 0.272
E65 Localised adiposity
0.000 0.731 0.269
E66 Obesity
0.000 0.738 0.262
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.257 0.742 0.001
E14.5 With peripheral circulatory complications
0.000 0.744 0.256
E14.1 With ketoacidosis
0.000 0.746 0.254
E67.8 Other specified hyperalimentation
0.000 0.747 0.252
E67.3 Hypervitaminosis D
0.000 0.747 0.252
E67.2 Megavitamin-B6 syndrome
0.000 0.747 0.252
E67.1 Hypercarotenaemia
0.000 0.747 0.252
E67.0 Hypervitaminosis A
0.000 0.747 0.252
E27 Other disorders of adrenal gland
0.000 0.760 0.240
E04.2 Non-toxic multinodular goitre
0.000 0.761 0.239
E27.1 Primary adrenocortical insufficiency
0.000 0.773 0.227
E66.8 Other obesity
0.000 0.774 0.226
L40-L45 Papulosquamous disorders
0.222 0.777 0.001
E24 Cushing's syndrome
0.000 0.797 0.203
E34 Other endocrine disorders
0.000 0.801 0.199
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.802 0.197
E32 Diseases of thymus
0.000 0.802 0.197
E31 Polyglandular dysfunction
0.000 0.802 0.197
E30 Disorders of puberty, not elsewhere classified
0.000 0.802 0.197
E25 Adrenogenital disorders
0.000 0.802 0.197
M07.6 Other enteropathic arthropathies
0.193 0.804 0.003
M07.5 Arthropathy in ulcerative colitis
0.193 0.804 0.003
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.193 0.804 0.003
M07.2 Psoriatic spondylitis
0.193 0.804 0.003
M07.1 Arthritis mutilans
0.193 0.804 0.003
M07.0 Distal interphalangeal psoriatic arthropathy
0.193 0.804 0.003
E66.1 Drug-induced obesity
0.000 0.812 0.188
E29 Testicular dysfunction
0.000 0.812 0.188
E22 Hyperfunction of pituitary gland
0.000 0.812 0.187
M06.9 Rheumatoid arthritis, unspecified
0.000 0.813 0.187
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.813 0.187
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.184 0.815 0.001
T40.8 Lysergide [LSD]
0.184 0.815 0.001
T40.7 Cannabis (derivatives)
0.184 0.815 0.001
T40.5 Cocaine
0.184 0.815 0.001
T40.3 Methadone
0.184 0.815 0.001
T40.1 Heroin
0.184 0.815 0.001
T40.0 Opium
0.184 0.815 0.001
E27.8 Other specified disorders of adrenal gland
0.000 0.815 0.185
E27.2 Addisonian crisis
0.000 0.815 0.185
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.816 0.184
E28 Ovarian dysfunction
0.000 0.820 0.179
E27.5 Adrenomedullary hyperfunction
0.000 0.828 0.172
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.828 0.172
E27.0 Other adrenocortical overactivity
0.000 0.828 0.172
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.828 0.172
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.171 0.828 0.001
E20 Hypoparathyroidism
0.000 0.831 0.169
T40.6 Other and unspecified narcotics
0.167 0.832 0.001
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.832 0.168
E66.0 Obesity due to excess calories
0.000 0.833 0.167
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.837 0.163
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.837 0.163
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.161 0.839 0.000
L44 Other papulosquamous disorders
0.159 0.840 0.001
L41 Parapsoriasis
0.159 0.840 0.001
L45 Papulosquamous disorders in diseases classified elsewhere
0.159 0.840 0.001
E34.8 Other specified endocrine disorders
0.000 0.842 0.158
E26 Hyperaldosteronism
0.001 0.844 0.156
E24.9 Cushing's syndrome, unspecified
0.000 0.844 0.155
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.848 0.152
E28.3 Primary ovarian failure
0.000 0.849 0.151
T20-T25 Burns and corrosions of external body surface, specified by site
0.150 0.850 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.149 0.851 0.000
E22.1 Hyperprolactinaemia
0.000 0.851 0.149
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.851 0.148
S80-S89 Injuries to the knee and lower leg
0.148 0.852 0.000
E24.8 Other Cushing's syndrome
0.000 0.854 0.145
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.854 0.145
E24.3 Ectopic ACTH syndrome
0.000 0.854 0.145
E24.1 Nelson's syndrome
0.000 0.854 0.145
E24.0 Pituitary-dependent Cushing's disease
0.000 0.854 0.145
S82 Fracture of lower leg, including ankle
0.144 0.856 0.000
E34.5 Androgen resistance syndrome
0.000 0.857 0.143
E34.4 Constitutional tall stature
0.000 0.857 0.143
E34.3 Short stature, not elsewhere classified
0.000 0.857 0.143
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.857 0.143
E34.1 Other hypersecretion of intestinal hormones
0.000 0.857 0.143
L42 Pityriasis rosea
0.141 0.858 0.001
E25.9 Adrenogenital disorder, unspecified
0.000 0.858 0.142
E25.8 Other adrenogenital disorders
0.000 0.858 0.142
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.858 0.142
E30.9 Disorder of puberty, unspecified
0.000 0.858 0.142
E30.8 Other disorders of puberty
0.000 0.858 0.142
E30.1 Precocious puberty
0.000 0.858 0.142
E30.0 Delayed puberty
0.000 0.858 0.142
E31.9 Polyglandular dysfunction, unspecified
0.000 0.858 0.142
E31.8 Other polyglandular dysfunction
0.000 0.858 0.142
E31.1 Polyglandular hyperfunction
0.000 0.858 0.142
E31.0 Autoimmune polyglandular failure
0.000 0.858 0.142
E32.9 Disease of thymus, unspecified
0.000 0.858 0.142
E32.8 Other diseases of thymus
0.000 0.858 0.142
E32.1 Abscess of thymus
0.000 0.858 0.142
E32.0 Persistent hyperplasia of thymus
0.000 0.858 0.142
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.858 0.142
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.858 0.142
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.858 0.142
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.859 0.141
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.138 0.860 0.002
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.138 0.860 0.002
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.138 0.860 0.002
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.138 0.860 0.002
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.138 0.860 0.002
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.138 0.860 0.002
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.138 0.860 0.002
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.138 0.860 0.002
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.138 0.860 0.002
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.138 0.860 0.002
M07.19 Arthritis mutilans (Site unspecified)
0.138 0.860 0.002
M07.18 Arthritis mutilans (Other)
0.138 0.860 0.002
M07.17 Arthritis mutilans (Ankle and foot)
0.138 0.860 0.002
M07.16 Arthritis mutilans (Lower leg)
0.138 0.860 0.002
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.138 0.860 0.002
M07.14 Arthritis mutilans (Hand)
0.138 0.860 0.002
M07.13 Arthritis mutilans (Forearm)
0.138 0.860 0.002
M07.12 Arthritis mutilans (Upper arm)
0.138 0.860 0.002
M07.11 Arthritis mutilans (Shoulder region)
0.138 0.860 0.002
M07.10 Arthritis mutilans (Multiple sites)
0.138 0.860 0.002
M07.29 Psoriatic spondylitis (Site unspecified)
0.138 0.860 0.002
M07.28 Psoriatic spondylitis (Other)
0.138 0.860 0.002
M07.27 Psoriatic spondylitis (Ankle and foot)
0.138 0.860 0.002
M07.26 Psoriatic spondylitis (Lower leg)
0.138 0.860 0.002
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.138 0.860 0.002
M07.24 Psoriatic spondylitis (Hand)
0.138 0.860 0.002
M07.23 Psoriatic spondylitis (Forearm)
0.138 0.860 0.002
M07.22 Psoriatic spondylitis (Upper arm)
0.138 0.860 0.002
M07.21 Psoriatic spondylitis (Shoulder region)
0.138 0.860 0.002
M07.20 Psoriatic spondylitis (Multiple sites)
0.138 0.860 0.002
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.138 0.860 0.002
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.138 0.860 0.002
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.138 0.860 0.002
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.138 0.860 0.002
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.138 0.860 0.002
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.138 0.860 0.002
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.138 0.860 0.002
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.138 0.860 0.002
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.138 0.860 0.002
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.138 0.860 0.002
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.138 0.860 0.002
M07.58 Arthropathy in ulcerative colitis (Other)
0.138 0.860 0.002
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.138 0.860 0.002
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.138 0.860 0.002
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.138 0.860 0.002
M07.54 Arthropathy in ulcerative colitis (Hand)
0.138 0.860 0.002
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.138 0.860 0.002
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.138 0.860 0.002
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.138 0.860 0.002
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.138 0.860 0.002
M07.69 Other enteropathic arthropathies (Site unspecified)
0.138 0.860 0.002
M07.68 Other enteropathic arthropathies (Other)
0.138 0.860 0.002
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.138 0.860 0.002
M07.66 Other enteropathic arthropathies (Lower leg)
0.138 0.860 0.002
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.138 0.860 0.002
M07.64 Other enteropathic arthropathies (Hand)
0.138 0.860 0.002
M07.63 Other enteropathic arthropathies (Forearm)
0.138 0.860 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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