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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2394963
log Bayes Factor = 43.7365
Chromosome 6   position 31,251,462  (GRCh37) Explore rs2394963 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.006 0.994
M45 Ankylosing spondylitis
0.000 0.035 0.965
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.059 0.941
L40.0 Psoriasis vulgaris
0.000 0.068 0.932
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.108 0.892
L40.8 Other psoriasis
0.000 0.204 0.796
L40.3 Pustulosis palmaris et plantaris
0.000 0.246 0.754
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.308 0.692
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.308 0.692
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.308 0.692
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.308 0.692
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.308 0.692
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.308 0.692
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.308 0.692
E03 Other hypothyroidism
0.000 0.352 0.648
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.413 0.587
M07.3 Other psoriatic arthropathies
0.000 0.437 0.563
E03.8 Other specified hypothyroidism
0.000 0.443 0.557
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.446 0.553
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.448 0.552
G35 Multiple sclerosis
0.000 0.459 0.541
E03.5 Myxoedema coma
0.000 0.535 0.465
E03.4 Atrophy of thyroid (acquired)
0.000 0.535 0.465
E03.3 Postinfectious hypothyroidism
0.000 0.535 0.465
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.550 0.450
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.551 0.449
G30-G32 Other degenerative diseases of the nervous system
0.000 0.556 0.444
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.566 0.434
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.566 0.434
Chapter VI Diseases of the nervous system
0.000 0.577 0.423
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.578 0.422
E03.1 Congenital hypothyroidism without goitre
0.000 0.593 0.407
G30 Alzheimer's disease
0.000 0.594 0.406
G31.2 Degeneration of nervous system due to alcohol
0.000 0.595 0.405
M07.38 Other psoriatic arthropathies (Other)
0.000 0.596 0.403
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.596 0.403
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.596 0.403
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.596 0.403
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.596 0.403
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.596 0.403
G31.8 Other specified degenerative diseases of nervous system
0.000 0.599 0.401
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.603 0.396
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.611 0.389
G30.9 Alzheimer's disease, unspecified
0.000 0.629 0.371
G31.0 Circumscribed brain atrophy
0.000 0.634 0.366
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.640 0.360
G62 Other polyneuropathies
0.000 0.644 0.356
G70-G73 Diseases of myoneural junction and muscle
0.000 0.654 0.346
G62.9 Polyneuropathy, unspecified
0.000 0.659 0.341
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.660 0.340
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.660 0.340
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.678 0.322
G30.1 Alzheimer's disease with late onset
0.000 0.688 0.312
G83 Other paralytic syndromes
0.000 0.688 0.312
G61 Inflammatory polyneuropathy
0.000 0.696 0.303
G30.0 Alzheimer's disease with early onset
0.000 0.699 0.301
G36 Other acute disseminated demyelination
0.000 0.700 0.300
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.701 0.299
G60 Hereditary and idiopathic neuropathy
0.000 0.703 0.297
G03 Meningitis due to other and unspecified causes
0.000 0.707 0.293
G83.4 Cauda equina syndrome
0.000 0.708 0.292
G00 Bacterial meningitis, not elsewhere classified
0.000 0.713 0.287
G30.8 Other Alzheimer's disease
0.000 0.715 0.285
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.715 0.285
G62.1 Alcoholic polyneuropathy
0.000 0.718 0.282
G64 Other disorders of peripheral nervous system
0.000 0.721 0.279
G71 Primary disorders of muscles
0.000 0.721 0.279
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.730 0.270
G83.9 Paralytic syndrome, unspecified
0.000 0.733 0.267
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.735 0.265
G61.8 Other inflammatory polyneuropathies
0.000 0.736 0.264
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.737 0.263
K90 Intestinal malabsorption
0.000 0.738 0.262
G72 Other myopathies
0.000 0.739 0.261
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.740 0.260
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.741 0.258
G62.2 Polyneuropathy due to other toxic agents
0.000 0.744 0.255
G70 Myasthenia gravis and other myoneural disorders
0.000 0.747 0.253
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.752 0.248
G60.0 Hereditary motor and sensory neuropathy
0.000 0.752 0.248
G81 Hemiplegia
0.000 0.754 0.246
G03.9 Meningitis, unspecified
0.000 0.756 0.244
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.756 0.244
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.758 0.242
M07 Psoriatic and enteropathic arthropathies
0.001 0.758 0.241
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.760 0.240
G06.0 Intracranial abscess and granuloma
0.000 0.760 0.240
G06.1 Intraspinal abscess and granuloma
0.000 0.760 0.240
G62.8 Other specified polyneuropathies
0.000 0.765 0.235
G00.1 Pneumococcal meningitis
0.000 0.768 0.232
G83.1 Monoplegia of lower limb
0.000 0.770 0.230
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.771 0.228
G83.5 Locked-in syndrome
0.000 0.776 0.224
G83.3 Monoplegia, unspecified
0.000 0.776 0.224
G83.0 Diplegia of upper limbs
0.000 0.776 0.224
L40-L45 Papulosquamous disorders
0.000 0.777 0.223
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.777 0.223
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.778 0.221
G61.1 Serum neuropathy
0.000 0.782 0.218
G36.9 Acute disseminated demyelination, unspecified
0.000 0.784 0.215
G36.8 Other specified acute disseminated demyelination
0.000 0.784 0.215
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.784 0.215
G60.3 Idiopathic progressive neuropathy
0.000 0.787 0.213
G60.2 Neuropathy in association with hereditary ataxia
0.000 0.787 0.213
G60.1 Refsum's disease
0.000 0.787 0.213
G00.9 Bacterial meningitis, unspecified
0.000 0.789 0.211
G03.8 Meningitis due to other specified causes
0.000 0.790 0.210
G03.2 Benign recurrent meningitis [Mollaret]
0.000 0.790 0.210
G03.1 Chronic meningitis
0.000 0.790 0.210
G03.0 Nonpyogenic meningitis
0.000 0.790 0.210
G06.2 Extradural and subdural abscess, unspecified
0.000 0.791 0.208
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.000 0.792 0.208
G72.9 Myopathy, unspecified
0.000 0.793 0.207
G00.8 Other bacterial meningitis
0.000 0.794 0.206
G00.3 Staphylococcal meningitis
0.000 0.794 0.206
G00.2 Streptococcal meningitis
0.000 0.794 0.206
G00.0 Haemophilus meningitis
0.000 0.794 0.206
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.794 0.206
G82 Paraplegia and tetraplegia
0.000 0.795 0.205
G81.1 Spastic hemiplegia
0.000 0.796 0.204
G71.9 Primary disorder of muscle, unspecified
0.000 0.800 0.200
G71.8 Other primary disorders of muscles
0.000 0.800 0.200
G71.2 Congenital myopathies
0.000 0.800 0.200
G83.8 Other specified paralytic syndromes
0.000 0.800 0.200
G70.0 Myasthenia gravis
0.000 0.800 0.200
G61.0 Guillain-Barre syndrome
0.000 0.800 0.200
G71.1 Myotonic disorders
0.000 0.801 0.199
G80 Infantile cerebral palsy
0.000 0.803 0.197
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.000 0.806 0.194
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.000 0.806 0.194
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.000 0.806 0.194
G61.9 Inflammatory polyneuropathy, unspecified
0.000 0.806 0.194
G36.0 Neuromyelitis optica [Devic]
0.000 0.807 0.193
G60.8 Other hereditary and idiopathic neuropathies
0.000 0.808 0.191
G12 Spinal muscular atrophy and related syndromes
0.000 0.810 0.190
G62.0 Drug-induced polyneuropathy
0.000 0.810 0.189
G72.8 Other specified myopathies
0.000 0.811 0.189
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.812 0.188
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.812 0.188
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.812 0.188
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.812 0.188
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.812 0.188
G63.1 Polyneuropathy in neoplastic disease
0.000 0.812 0.188
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.812 0.188
G72.0 Drug-induced myopathy
0.000 0.812 0.188
K90.3 Pancreatic steatorrhoea
0.000 0.812 0.188
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.812 0.188
K90.1 Tropical sprue
0.000 0.812 0.188
G72.3 Periodic paralysis
0.000 0.813 0.187
G72.2 Myopathy due to other toxic agents
0.000 0.813 0.187
G72.1 Alcoholic myopathy
0.000 0.813 0.187
G37 Other demyelinating diseases of central nervous system
0.000 0.815 0.185
K90.8 Other intestinal malabsorption
0.000 0.817 0.182
G70.8 Other specified myoneural disorders
0.000 0.818 0.182
G70.2 Congenital and developmental myasthenia
0.000 0.818 0.182
G70.1 Toxic myoneural disorders
0.000 0.818 0.182
G71.0 Muscular dystrophy
0.000 0.821 0.179
G73.7 Myopathy other diseases classified elsewhere
0.000 0.822 0.178
G73.6 Myopathy in metabolic diseases
0.000 0.822 0.178
G73.5 Myopathy in endocrine diseases
0.000 0.822 0.178
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.000 0.822 0.178
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.000 0.822 0.178
G73.2 Other myasthenic syndromes in neoplastic disease
0.000 0.822 0.178
G73.1 Eaton-Lambert syndrome
0.000 0.822 0.178
G73.0 Myasthenic syndromes in endocrine diseases
0.000 0.822 0.178
G81.0 Flaccid hemiplegia
0.000 0.823 0.176
G72.4 Inflammatory myopathy, not elsewhere classified
0.000 0.826 0.174
M07.6 Other enteropathic arthropathies
0.001 0.827 0.173
M07.5 Arthropathy in ulcerative colitis
0.001 0.827 0.173
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.827 0.173
M07.2 Psoriatic spondylitis
0.001 0.827 0.173
M07.1 Arthritis mutilans
0.001 0.827 0.173
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.827 0.173
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.828 0.172
G63.2 Diabetic polyneuropathy
0.000 0.828 0.172
G82.1 Spastic paraplegia
0.000 0.831 0.169
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.000 0.833 0.167
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.000 0.836 0.164
G02.1 Meningitis in mycoses
0.000 0.836 0.164
G70.9 Myoneural disorder, unspecified
0.000 0.836 0.164
G83.2 Monoplegia of upper limb
0.000 0.837 0.162
L44 Other papulosquamous disorders
0.000 0.840 0.160
L41 Parapsoriasis
0.000 0.840 0.160
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.840 0.160
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.000 0.840 0.160
G04.1 Tropical spastic paraplegia
0.000 0.840 0.160
G11 Hereditary ataxia
0.000 0.842 0.158
L42 Pityriasis rosea
0.000 0.845 0.155
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.845 0.154
G12.2 Motor neuron disease
0.000 0.846 0.154
K90.9 Intestinal malabsorption, unspecified
0.000 0.849 0.151
G14 Postpolio syndrome
0.000 0.850 0.150
G80.2 Infantile hemiplegia
0.000 0.851 0.149
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.000 0.851 0.149
G82.3 Flaccid tetraplegia
0.000 0.853 0.147
G82.0 Flaccid paraplegia
0.000 0.853 0.147
G80.0 Spastic cerebral palsy
0.000 0.854 0.146
G82.4 Spastic tetraplegia
0.000 0.858 0.142
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.859 0.141
G82.5 Tetraplegia, unspecified
0.000 0.859 0.141
G80.8 Other infantile cerebral palsy
0.000 0.859 0.141
G80.4 Ataxic cerebral palsy
0.000 0.859 0.141
G80.3 Dyskinetic cerebral palsy
0.000 0.859 0.141
D64.9 Anaemia, unspecified
0.000 0.859 0.141
G12.9 Spinal muscular atrophy, unspecified
0.000 0.863 0.136
G12.8 Other spinal muscular atrophies and related syndromes
0.000 0.863 0.136
G12.1 Other inherited spinal muscular atrophy
0.000 0.863 0.136
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.000 0.863 0.136
G02.0 Meningitis in viral diseases classified elsewhere
0.000 0.866 0.134
D64 Other anaemias
0.000 0.866 0.134
G81.9 Hemiplegia, unspecified
0.000 0.866 0.134
G37.5 Concentric sclerosis [Balo]
0.000 0.867 0.133
G37.4 Subacute necrotising myelitis
0.000 0.867 0.133
G37.2 Central pontine myelinolysis
0.000 0.867 0.133
G37.1 Central demyelination of corpus callosum
0.000 0.867 0.133
G37.0 Diffuse sclerosis
0.000 0.867 0.133
G04.0 Acute disseminated encephalitis
0.000 0.869 0.130
G10 Huntington's disease
0.000 0.871 0.129
G80.1 Spastic diplegia
0.000 0.875 0.125
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.875 0.124
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.001 0.875 0.124
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.001 0.875 0.124
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.001 0.875 0.124
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.001 0.875 0.124
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.001 0.875 0.124
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.001 0.875 0.124
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.001 0.875 0.124
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.001 0.875 0.124
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.001 0.875 0.124
M07.19 Arthritis mutilans (Site unspecified)
0.001 0.875 0.124
M07.18 Arthritis mutilans (Other)
0.001 0.875 0.124
M07.17 Arthritis mutilans (Ankle and foot)
0.001 0.875 0.124
M07.16 Arthritis mutilans (Lower leg)
0.001 0.875 0.124
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.001 0.875 0.124
M07.14 Arthritis mutilans (Hand)
0.001 0.875 0.124
M07.13 Arthritis mutilans (Forearm)
0.001 0.875 0.124
M07.12 Arthritis mutilans (Upper arm)
0.001 0.875 0.124
M07.11 Arthritis mutilans (Shoulder region)
0.001 0.875 0.124
M07.10 Arthritis mutilans (Multiple sites)
0.001 0.875 0.124
M07.29 Psoriatic spondylitis (Site unspecified)
0.001 0.875 0.124
M07.28 Psoriatic spondylitis (Other)
0.001 0.875 0.124
M07.27 Psoriatic spondylitis (Ankle and foot)
0.001 0.875 0.124
M07.26 Psoriatic spondylitis (Lower leg)
0.001 0.875 0.124
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.001 0.875 0.124
M07.24 Psoriatic spondylitis (Hand)
0.001 0.875 0.124
M07.23 Psoriatic spondylitis (Forearm)
0.001 0.875 0.124
M07.22 Psoriatic spondylitis (Upper arm)
0.001 0.875 0.124
M07.21 Psoriatic spondylitis (Shoulder region)
0.001 0.875 0.124
M07.20 Psoriatic spondylitis (Multiple sites)
0.001 0.875 0.124
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.001 0.875 0.124
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.001 0.875 0.124
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.001 0.875 0.124
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.001 0.875 0.124
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.001 0.875 0.124
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.001 0.875 0.124
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.001 0.875 0.124
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.001 0.875 0.124
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.001 0.875 0.124
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.001 0.875 0.124
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.001 0.875 0.124
M07.58 Arthropathy in ulcerative colitis (Other)
0.001 0.875 0.124
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.001 0.875 0.124
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.001 0.875 0.124
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.001 0.875 0.124
M07.54 Arthropathy in ulcerative colitis (Hand)
0.001 0.875 0.124
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.001 0.875 0.124
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.001 0.875 0.124
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.001 0.875 0.124
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.001 0.875 0.124
M07.69 Other enteropathic arthropathies (Site unspecified)
0.001 0.875 0.124
M07.68 Other enteropathic arthropathies (Other)
0.001 0.875 0.124
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.001 0.875 0.124
M07.66 Other enteropathic arthropathies (Lower leg)
0.001 0.875 0.124
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.001 0.875 0.124
M07.64 Other enteropathic arthropathies (Hand)
0.001 0.875 0.124
M07.63 Other enteropathic arthropathies (Forearm)
0.001 0.875 0.124
M07.62 Other enteropathic arthropathies (Upper arm)
0.001 0.875 0.124
M07.61 Other enteropathic arthropathies (Shoulder region)
0.001 0.875 0.124
M07.60 Other enteropathic arthropathies (Multiple sites)
0.001 0.875 0.124
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.000 0.876 0.124
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.000 0.876 0.124
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.000 0.876 0.124
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.000 0.876 0.124
D60-D64 Aplastic and other anaemias
0.000 0.876 0.124
G11.4 Hereditary spastic paraplegia
0.000 0.879 0.121
D50 Iron deficiency anaemia
0.000 0.880 0.120
D50-D53 Nutritional anaemias
0.000 0.880 0.120
D61 Other aplastic anaemias
0.000 0.881 0.119
D50.9 Iron deficiency anaemia, unspecified
0.000 0.883 0.117
D61.9 Aplastic anaemia, unspecified
0.000 0.883 0.117
D64.8 Other specified anaemias
0.000 0.885 0.115
L41.9 Parapsoriasis, unspecified
0.000 0.885 0.115
L41.8 Other parapsoriasis
0.000 0.885 0.115
L41.5 Retiform parapsoriasis
0.000 0.885 0.115
L41.4 Large plaque parapsoriasis
0.000 0.885 0.115
L41.3 Small plaque parapsoriasis
0.000 0.885 0.115
L41.2 Lymphomatoid papulosis
0.000 0.885 0.115
L41.1 Pityriasis lichenoides chronica
0.000 0.885 0.115
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.885 0.115
L44.9 Papulosquamous disorder, unspecified
0.000 0.885 0.115
L44.8 Other specified papulosquamous disorders
0.000 0.885 0.115
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.885 0.115
L44.3 Lichen ruber moniliformis
0.000 0.885 0.115
L44.2 Lichen striatus
0.000 0.885 0.115
L44.1 Lichen nitidus
0.000 0.885 0.115
L44.0 Pityriasis rubra pilaris
0.000 0.885 0.115
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.886 0.114
G11.8 Other hereditary ataxias
0.000 0.886 0.114
G11.3 Cerebellar ataxia with defective DNA repair
0.000 0.886 0.114
G11.2 Late-onset cerebellar ataxia
0.000 0.886 0.114
G11.0 Congenital nonprogressive ataxia
0.000 0.886 0.114
G20-G26 Extrapyramidal and movement disorders
0.000 0.888 0.112
D50.8 Other iron deficiency anaemias
0.000 0.891 0.109
G11.1 Early-onset cerebellar ataxia
0.000 0.895 0.104
D80-D89 Certain disorders involving the immune mechanism
0.000 0.895 0.105
D51 Vitamin B12 deficiency anaemia
0.000 0.897 0.103
G11.9 Hereditary ataxia, unspecified
0.000 0.900 0.100
D52 Folate deficiency anaemia
0.000 0.902 0.098
D64.4 Congenital dyserythropoietic anaemia
0.000 0.904 0.096
D64.3 Other sideroblastic anaemias
0.000 0.904 0.096
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.904 0.096
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.904 0.096
D64.0 Hereditary sideroblastic anaemia
0.000 0.904 0.096
G80.9 Infantile cerebral palsy, unspecified
0.000 0.904 0.096
D80 Immunodeficiency with predominantly antibody defects
0.000 0.905 0.095
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.908 0.092
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.910 0.090
G90-G99 Other disorders of the nervous system
0.000 0.910 0.090
D53 Other nutritional anaemias
0.000 0.911 0.089
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.911 0.089
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.913 0.087
D50.1 Sideropenic dysphagia
0.000 0.914 0.086
D61.8 Other specified aplastic anaemias
0.000 0.915 0.085
D61.3 Idiopathic aplastic anaemia
0.000 0.915 0.085
D61.2 Aplastic anaemia due to other external agents
0.000 0.915 0.085
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.915 0.085
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.917 0.083
D52.9 Folate deficiency anaemia, unspecified
0.000 0.917 0.083
M45-M49 Spondylopathies
0.000 0.918 0.082
G25 Other extrapyramidal and movement disorders
0.000 0.918 0.081
G21 Secondary Parkinsonism
0.000 0.920 0.080
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.920 0.080
G22 Parkinsonism in diseases classified elsewhere
0.000 0.920 0.080
G98 Other disorders of nervous system, not elsewhere classified
0.000 0.920 0.080
D61.0 Constitutional aplastic anaemia
0.000 0.920 0.080
K75 Other inflammatory liver diseases
0.000 0.922 0.078
D86 Sarcoidosis
0.000 0.922 0.078
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.923 0.077
D61.1 Drug-induced aplastic anaemia
0.000 0.923 0.077
D55-D59 Haemolytic anaemias
0.000 0.923 0.077
G93 Other disorders of brain
0.000 0.924 0.076
D83 Common variable immunodeficiency
0.000 0.924 0.076
K75.8 Other specified inflammatory liver diseases
0.000 0.924 0.076
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.924 0.076
D81 Combined immunodeficiencies
0.000 0.925 0.075
G23 Other degenerative diseases of basal ganglia
0.000 0.925 0.075
N39.3 Stress incontinence
0.075 0.925 0.000
K75.4 Autoimmune hepatitis
0.000 0.925 0.075
D51.2 Transcobalamin II deficiency
0.000 0.926 0.074
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.926 0.074
G82.2 Paraplegia, unspecified
0.000 0.926 0.074
D84 Other immunodeficiencies
0.000 0.926 0.073
K75.0 Abscess of liver
0.000 0.927 0.073
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.928 0.072
K70-K77 Diseases of liver
0.000 0.928 0.072
G93.0 Cerebral cysts
0.000 0.928 0.072
K70 Alcoholic liver disease
0.000 0.928 0.072
D52.8 Other folate deficiency anaemias
0.000 0.929 0.071
D52.1 Drug-induced folate deficiency anaemia
0.000 0.929 0.071
D52.0 Dietary folate deficiency anaemia
0.000 0.929 0.071
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.930 0.070
G94 Other disorders of brain in diseases classified elsewhere
0.000 0.931 0.069
D86.3 Sarcoidosis of skin
0.000 0.931 0.069
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.932 0.068
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.932 0.068
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.932 0.068
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.932 0.068
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.932 0.068
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.932 0.068
D86.0 Sarcoidosis of lung
0.000 0.932 0.068
D53.9 Nutritional anaemia, unspecified
0.000 0.933 0.067
K72 Hepatic failure, not elsewhere classified
0.000 0.933 0.067
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.933 0.067
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.933 0.067
D82 Immunodeficiency associated with other major defects
0.000 0.933 0.066
G25.0 Essential tremor
0.000 0.933 0.067
K70.1 Alcoholic hepatitis
0.000 0.933 0.067
K73 Chronic hepatitis, not elsewhere classified
0.000 0.933 0.066
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.934 0.066
G93.5 Compression of brain
0.000 0.934 0.066
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.934 0.066
G25.3 Myoclonus
0.000 0.934 0.066
L43 Lichen planus
0.001 0.935 0.064
G92 Toxic encephalopathy
0.000 0.935 0.065
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.935 0.065
D53.8 Other specified nutritional anaemias
0.000 0.936 0.064
D53.2 Scorbutic anaemia
0.000 0.936 0.064
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.936 0.064
D53.0 Protein deficiency anaemia
0.000 0.936 0.064
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.936 0.064
D60.8 Other acquired pure red cell aplasias
0.000 0.936 0.064
D60.1 Transient acquired pure red cell aplasia
0.000 0.936 0.064
D60.0 Chronic acquired pure red cell aplasia
0.000 0.936 0.064
K70.4 Alcoholic hepatic failure
0.000 0.936 0.064
K70.0 Alcoholic fatty liver
0.000 0.936 0.064
D89.1 Cryoglobulinaemia
0.000 0.937 0.063
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.937 0.063
D89.3 Immune reconstitution syndrome
0.000 0.937 0.063
G91 Hydrocephalus
0.000 0.938 0.062
G25.2 Other specified forms of tremor
0.000 0.939 0.061
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.001 0.939 0.060
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.000 0.940 0.060
K72.9 Hepatic failure, unspecified
0.000 0.940 0.060
D84.9 Immunodeficiency, unspecified
0.000 0.940 0.060
E00-E07 Disorders of thyroid gland
0.000 0.940 0.060
D59 Acquired haemolytic anaemia
0.000 0.941 0.059
G93.8 Other specified disorders of brain
0.000 0.941 0.059
D62 Acute posthaemorrhagic anaemia
0.000 0.941 0.059
G25.6 Drug-induced tics and other tics of organic origin
0.000 0.941 0.059
G25.5 Other chorea
0.000 0.941 0.059
G25.4 Drug-induced chorea
0.000 0.941 0.059
G25.1 Drug-induced tremor
0.000 0.941 0.059
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.942 0.058
K72.0 Acute and subacute hepatic failure
0.000 0.942 0.058
G21.9 Secondary Parkinsonism, unspecified
0.000 0.942 0.058
G21.8 Other secondary Parkinsonism
0.000 0.942 0.058
G21.4 Vascular parkinsonism
0.000 0.942 0.058
G21.3 Postencephalitic Parkinsonism
0.000 0.942 0.058
G21.2 Secondary Parkinsonism due to other external agents
0.000 0.942 0.058
G21.1 Other drug-induced secondary Parkinsonism
0.000 0.942 0.058
G21.0 Malignant neuroleptic syndrome
0.000 0.942 0.058
M46 Other inflammatory spondylopathies
0.000 0.943 0.057
K73.9 Chronic hepatitis, unspecified
0.000 0.943 0.057
D86.1 Sarcoidosis of lymph nodes
0.000 0.943 0.057
G93.1 Anoxic brain damage, not elsewhere classified
0.000 0.943 0.057
K75.2 Nonspecific reactive hepatitis
0.000 0.944 0.056
K75.1 Phlebitis of portal vein
0.000 0.944 0.056
D83.9 Common variable immunodeficiency, unspecified
0.000 0.944 0.056
D55 Anaemia due to enzyme disorders
0.000 0.945 0.055
G93.7 Reye's syndrome
0.000 0.945 0.055
D83.8 Other common variable immunodeficiencies
0.000 0.945 0.055
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.945 0.055
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.945 0.055
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.945 0.055
G94.1 Hydrocephalus in neoplastic disease
0.000 0.945 0.054
D81.9 Combined immunodeficiency, unspecified
0.000 0.946 0.054
D81.8 Other combined immunodeficiencies
0.000 0.946 0.054
D81.7 Major histocompatibility complex class II deficiency
0.000 0.946 0.054
D81.6 Major histocompatibility complex class I deficiency
0.000 0.946 0.054
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.946 0.054
D81.4 Nezelof's syndrome
0.000 0.946 0.054
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.946 0.054
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.946 0.054
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.946 0.054
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.946 0.054
G23.9 Degenerative disease of basal ganglia, unspecified
0.000 0.946 0.054
G23.3 Multiple system atrophy, cerebellar type
0.000 0.946 0.054
G23.2 Striatonigral degeneration
0.000 0.946 0.054
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.000 0.946 0.054
G23.0 Hallervorden-Spatz disease
0.000 0.946 0.054
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.947 0.053
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.947 0.053
G25.9 Extrapyramidal and movement disorder, unspecified
0.000 0.947 0.053
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.947 0.052
K70.9 Alcoholic liver disease, unspecified
0.000 0.948 0.052
K77 Liver disorders in diseases classified elsewhere
0.000 0.948 0.052
D58 Other hereditary haemolytic anaemias
0.000 0.948 0.052
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.948 0.052
D56 Thalassaemia
0.000 0.948 0.052
D84.1 Defects in the complement system
0.000 0.948 0.051
D57 Sickle-cell disorders
0.000 0.948 0.051
G93.2 Benign intracranial hypertension
0.000 0.949 0.051
G91.1 Obstructive hydrocephalus
0.000 0.949 0.051
M49 Spondylopathies in diseases classified elsewhere
0.000 0.949 0.051
G24 Dystonia
0.000 0.949 0.051
G93.4 Encephalopathy, unspecified
0.000 0.949 0.051
R31 Unspecified haematuria
0.051 0.949 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.000 0.950 0.050
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.000 0.950 0.050
G93.3 Postviral fatigue syndrome
0.000 0.950 0.050
G97.8 Other postprocedural disorders of nervous system
0.000 0.950 0.050
G94.2 Hydrocephalus in other diseases classified elsewhere
0.000 0.950 0.049
G23.8 Other specified degenerative diseases of basal ganglia
0.000 0.951 0.048
G93.9 Disorder of brain, unspecified
0.000 0.951 0.049
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.952 0.048
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.952 0.048
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.952 0.048
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.952 0.048
D82.2 Immunodeficiency with short-limbed stature
0.000 0.952 0.048
D82.0 Wiskott-Aldrich syndrome
0.000 0.952 0.048
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.952 0.048
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.952 0.048

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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