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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2395182
log Bayes Factor = 227.918
Chromosome 6   position 32,413,317  (GRCh37) Explore rs2395182 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
E11.9 Without complications
0.000 0.000 1.000
K51 Ulcerative colitis
0.999 0.001 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.999 0.001 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
G37 Other demyelinating diseases of central nervous system
0.999 0.001 0.000
E14.3 With ophthalmic complications
0.000 0.002 0.998
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.002 0.998
L40-L45 Papulosquamous disorders
0.000 0.002 0.998
G37.9 Demyelinating disease of central nervous system, unspecified
0.998 0.002 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.004 0.996
L40.5 Arthropathic psoriasis
0.000 0.004 0.996
L43 Lichen planus
0.000 0.005 0.995
E83.1 Disorders of iron metabolism
0.994 0.006 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.993 0.007 0.000
L43.9 Lichen planus, unspecified
0.000 0.008 0.992
M35.3 Polymyalgia rheumatica
0.000 0.010 0.990
L40.9 Psoriasis, unspecified
0.000 0.012 0.988
M06.0 Seronegative rheumatoid arthritis
0.000 0.017 0.983
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.018 0.982
E14.9 Without complications
0.000 0.019 0.981
K51.2 Ulcerative (chronic) proctitis
0.979 0.021 0.000
E10.2 With renal complications
0.000 0.022 0.978
E11.1 With ketoacidosis
0.000 0.022 0.978
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.022 0.978
M07 Psoriatic and enteropathic arthropathies
0.000 0.023 0.977
E10.5 With peripheral circulatory complications
0.000 0.030 0.970
M07.3 Other psoriatic arthropathies
0.000 0.037 0.963
K90 Intestinal malabsorption
0.000 0.038 0.962
H36 Retinal disorders in diseases classified elsewhere
0.000 0.040 0.960
K90-K93 Other diseases of the digestive system
0.000 0.046 0.954
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.049 0.951
K82.8 Other specified diseases of gallbladder
0.000 0.049 0.951
K82 Other diseases of gallbladder
0.000 0.052 0.948
K51.8 Other ulcerative colitis
0.948 0.052 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.054 0.946
M35 Other systemic involvement of connective tissue
0.000 0.054 0.946
Chapter XI Diseases of the digestive system
0.000 0.056 0.944
# Top node
0.000 0.057 0.943
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.058 0.942
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.934 0.064 0.001
M20-M25 Other joint disorders
0.000 0.065 0.935
E06 Thyroiditis
0.000 0.069 0.931
M06.3 Rheumatoid nodule
0.000 0.069 0.931
H30-H36 Disorders of choroid and retina
0.000 0.069 0.931
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.069 0.931
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.929 0.071 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.071 0.929
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.071 0.929
E11.4 With neurological complications
0.000 0.071 0.929
D80-D89 Certain disorders involving the immune mechanism
0.927 0.073 0.000
D68 Other coagulation defects
0.927 0.073 0.000
J45 Asthma
0.000 0.074 0.926
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.074 0.926
L40.0 Psoriasis vulgaris
0.000 0.075 0.925
E10.8 With unspecified complications
0.000 0.076 0.924
D86 Sarcoidosis
0.924 0.076 0.000
D50-D53 Nutritional anaemias
0.921 0.079 0.000
D86.0 Sarcoidosis of lung
0.920 0.080 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.084 0.916
E11.5 With peripheral circulatory complications
0.000 0.084 0.916
D51 Vitamin B12 deficiency anaemia
0.911 0.089 0.000
E13 Other specified diabetes mellitus
0.000 0.089 0.911
E11.3 With ophthalmic complications
0.000 0.090 0.910
D68.9 Coagulation defect, unspecified
0.907 0.093 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.094 0.906
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.102 0.898
D55-D59 Haemolytic anaemias
0.897 0.102 0.001
H43-H45 Disorders of vitreous body and globe
0.000 0.103 0.897
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.104 0.896
J40-J47 Chronic lower respiratory diseases
0.000 0.106 0.894
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.891 0.109 0.000
H43 Disorders of vitreous body
0.000 0.109 0.891
H34 Retinal vascular occlusions
0.000 0.112 0.888
E06.3 Autoimmune thyroiditis
0.000 0.118 0.882
E11.6 With other specified complications
0.000 0.122 0.878
D59 Acquired haemolytic anaemia
0.869 0.131 0.000
E11.2 With renal complications
0.000 0.131 0.869
J46 Status asthmaticus
0.000 0.135 0.865
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.139 0.861
K91.3 Postoperative intestinal obstruction
0.000 0.140 0.860
Chapter X Diseases of the respiratory system
0.000 0.143 0.857
K70-K77 Diseases of liver
0.000 0.144 0.856
M06.34 Rheumatoid nodule (Hand)
0.000 0.145 0.855
K82.1 Hydrops of gallbladder
0.000 0.145 0.855
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.147 0.853
K81 Cholecystitis
0.000 0.152 0.848
E13.9 Without complications
0.000 0.154 0.846
E03.8 Other specified hypothyroidism
0.000 0.156 0.844
M14 Arthropathies in other diseases classified elsewhere
0.000 0.157 0.843
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.843 0.157 0.000
D52 Folate deficiency anaemia
0.842 0.158 0.000
D59.1 Other autoimmune haemolytic anaemias
0.842 0.158 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.163 0.837
H43.3 Other vitreous opacities
0.000 0.165 0.835
E16.1 Other hypoglycaemia
0.000 0.170 0.830
M06.4 Inflammatory polyarthropathy
0.000 0.171 0.829
L43.8 Other lichen planus
0.000 0.179 0.821
K81.1 Chronic cholecystitis
0.000 0.179 0.821
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.179 0.821
K75 Other inflammatory liver diseases
0.000 0.181 0.819
M30 Polyarteritis nodosa and related conditions
0.000 0.181 0.819
D68.5 Primary Thrombophilia
0.815 0.185 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.814 0.186 0.000
H43.1 Vitreous haemorrhage
0.000 0.190 0.810
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.191 0.809
D68.8 Other specified coagulation defects
0.809 0.191 0.000
Chapter VI Diseases of the nervous system
0.802 0.192 0.006
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.193 0.807
K51.5 Mucosal proctocolitis
0.806 0.194 0.000
K75.4 Autoimmune hepatitis
0.000 0.201 0.799
G37.8 Other specified demyelinating diseases of central nervous system
0.798 0.201 0.000
E11.8 With unspecified complications
0.000 0.202 0.798
E14.4 With neurological complications
0.000 0.207 0.792
J43 Emphysema
0.000 0.209 0.791
E14.8 With unspecified complications
0.000 0.211 0.789
D52.9 Folate deficiency anaemia, unspecified
0.786 0.214 0.000
H43.8 Other disorders of vitreous body
0.000 0.216 0.784
E07 Other disorders of thyroid
0.000 0.219 0.780
K82.2 Perforation of gallbladder
0.000 0.220 0.780
H34.2 Other retinal artery occlusions
0.000 0.221 0.779
G20-G26 Extrapyramidal and movement disorders
0.776 0.222 0.001
M24 Other specific joint derangements
0.000 0.228 0.772
L40.8 Other psoriasis
0.000 0.232 0.768
G80-G83 Cerebral palsy and other paralytic syndromes
0.765 0.234 0.001
M14.6 Neuropathic arthropathy
0.000 0.235 0.765
H34.8 Other retinal vascular occlusions
0.000 0.236 0.764
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.239 0.761
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.243 0.757
K91.1 Postgastric surgery syndromes
0.000 0.246 0.754
E05.9 Thyrotoxicosis, unspecified
0.000 0.247 0.753
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.248 0.752
G25 Other extrapyramidal and movement disorders
0.747 0.253 0.000
M34 Systemic sclerosis
0.000 0.256 0.744
M24.1 Other articular cartilage disorders
0.000 0.258 0.742
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.263 0.737
J33.9 Nasal polyp, unspecified
0.000 0.263 0.737
G50-G59 Nerve, nerve root and plexus disorders
0.730 0.266 0.004
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.267 0.733
K73 Chronic hepatitis, not elsewhere classified
0.000 0.267 0.733
G57 Mononeuropathies of lower limb
0.731 0.268 0.000
D68.1 Hereditary factor XI deficiency
0.731 0.269 0.000
M35.7 Hypermobility syndrome
0.000 0.270 0.730
D86.1 Sarcoidosis of lymph nodes
0.729 0.271 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.728 0.272 0.000
D68.2 Hereditary deficiency of other clotting factors
0.727 0.273 0.000
H34.1 Central retinal artery occlusion
0.000 0.273 0.727
J44 Other chronic obstructive pulmonary disease
0.000 0.273 0.727
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.277 0.723
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.278 0.722
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.721 0.279 0.000
K82.3 Fistula of gallbladder
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.716 0.283 0.000
L40.4 Guttate psoriasis
0.000 0.284 0.716
L40.3 Pustulosis palmaris et plantaris
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
L40.1 Generalised pustular psoriasis
0.000 0.284 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
L44 Other papulosquamous disorders
0.000 0.285 0.715
L41 Parapsoriasis
0.000 0.285 0.715
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.285 0.715
M35.1 Other overlap syndromes
0.000 0.286 0.714
M91-M94 Chondropathies
0.000 0.286 0.714
L43.3 Subacute (active) lichen planus
0.000 0.287 0.713
L43.2 Lichenoid drug reaction
0.000 0.287 0.713
L43.1 Bullous lichen planus
0.000 0.287 0.713
L43.0 Hypertrophic lichen planus
0.000 0.287 0.713
E40-E46 Malnutrition
0.000 0.288 0.712
H30 Chorioretinal inflammation
0.000 0.291 0.709
J33 Nasal polyp
0.000 0.292 0.708
D68.6 Other Thrombophilia
0.706 0.294 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.295 0.705
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.295 0.705
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.295 0.705
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.295 0.705
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.295 0.705
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.295 0.705
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.295 0.705
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.296 0.704
K72 Hepatic failure, not elsewhere classified
0.000 0.297 0.703
M35.2 Behcet's disease
0.000 0.297 0.703
D66 Hereditary factor VIII deficiency
0.702 0.298 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.702 0.298 0.000
M07.5 Arthropathy in ulcerative colitis
0.000 0.299 0.701
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.299 0.701
M07.2 Psoriatic spondylitis
0.000 0.299 0.701
M07.1 Arthritis mutilans
0.000 0.299 0.701
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.299 0.701
G20 Parkinson's disease
0.698 0.302 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.305 0.695
G57.6 Lesion of plantar nerve
0.694 0.306 0.000
M12 Other specific arthropathies
0.000 0.306 0.694
M07.38 Other psoriatic arthropathies (Other)
0.000 0.309 0.691
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.309 0.691
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.309 0.691
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.309 0.691
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.309 0.691
J43.9 Emphysema, unspecified
0.000 0.310 0.690
D84 Other immunodeficiencies
0.690 0.310 0.000
G83 Other paralytic syndromes
0.690 0.310 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.310 0.690
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.310 0.690
K90.1 Tropical sprue
0.000 0.310 0.690
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.312 0.688
M45-M49 Spondylopathies
0.000 0.312 0.688
H43.9 Disorder of vitreous body, unspecified
0.000 0.315 0.685
D59.9 Acquired haemolytic anaemia, unspecified
0.684 0.316 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.316 0.684
M30.0 Polyarteritis nodosa
0.000 0.318 0.682
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.319 0.681
K74 Fibrosis and cirrhosis of liver
0.000 0.319 0.681
D57 Sickle-cell disorders
0.680 0.320 0.001
M11 Other crystal arthropathies
0.000 0.321 0.679
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.322 0.678
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.322 0.678
M35.5 Multifocal fibrosclerosis
0.000 0.322 0.678
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.322 0.678
K81.9 Cholecystitis, unspecified
0.000 0.322 0.678
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.322 0.678
H43.2 Crystalline deposits in vitreous body
0.000 0.323 0.677
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.324 0.676
M65-M68 Disorders of synovium and tendon
0.000 0.324 0.676
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.676 0.324 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.324 0.676
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.324 0.675
D68.4 Acquired coagulation factor deficiency
0.674 0.326 0.000
K86 Other diseases of pancreas
0.000 0.326 0.674
J86 Pyothorax
0.000 0.327 0.673
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.330 0.670
D86.9 Sarcoidosis, unspecified
0.670 0.330 0.000
K75.9 Inflammatory liver disease, unspecified
0.000 0.331 0.669
E06.5 Other chronic thyroiditis
0.000 0.332 0.668
E06.4 Drug-induced thyroiditis
0.000 0.332 0.668
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.332 0.668
E06.1 Subacute thyroiditis
0.000 0.332 0.668
E06.0 Acute thyroiditis
0.000 0.332 0.668
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.332 0.668
M06.38 Rheumatoid nodule (Other)
0.000 0.332 0.668
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.332 0.668
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.332 0.668
M06.33 Rheumatoid nodule (Forearm)
0.000 0.332 0.668
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.332 0.668
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.332 0.668
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.332 0.668
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.332 0.667
M45 Ankylosing spondylitis
0.000 0.334 0.666
D67 Hereditary factor IX deficiency
0.666 0.334 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.334 0.666
E06.9 Thyroiditis, unspecified
0.000 0.334 0.666
D83 Common variable immunodeficiency
0.664 0.335 0.000
D82 Immunodeficiency associated with other major defects
0.664 0.335 0.000
D81 Combined immunodeficiencies
0.664 0.335 0.000
J45.1 Nonallergic asthma
0.000 0.336 0.664
H34.9 Retinal vascular occlusion, unspecified
0.000 0.337 0.663
D86.3 Sarcoidosis of skin
0.662 0.337 0.000
L42 Pityriasis rosea
0.000 0.338 0.662
M07.6 Other enteropathic arthropathies
0.000 0.339 0.660
D86.8 Sarcoidosis of other and combined sites
0.659 0.340 0.000
E11.0 With coma
0.000 0.343 0.656
K82.9 Disease of gallbladder, unspecified
0.000 0.344 0.656
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.654 0.346 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.653 0.347 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.653 0.347 0.000
D51.2 Transcobalamin II deficiency
0.653 0.347 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.653 0.347 0.000
E13.8 With unspecified complications
0.000 0.347 0.653
E13.7 With multiple complications
0.000 0.347 0.653
E13.6 With other specified complications
0.000 0.347 0.653
E13.5 With peripheral circulatory complications
0.000 0.347 0.653
E13.4 With neurological complications
0.000 0.347 0.653
E13.3 With ophthalmic complications
0.000 0.347 0.653
E13.2 With renal complications
0.000 0.347 0.653
E13.1 With ketoacidosis
0.000 0.347 0.653
E13.0 With coma
0.000 0.347 0.653
G57.8 Other mononeuropathies of lower limb
0.653 0.347 0.000
G57.1 Meralgia paraesthetica
0.652 0.348 0.000
D56 Thalassaemia
0.651 0.349 0.001
K51.4 Pseudopolyposis of colon
0.649 0.351 0.000
D55 Anaemia due to enzyme disorders
0.643 0.356 0.001
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.357 0.643
G81 Hemiplegia
0.640 0.359 0.000
M10 Gout
0.000 0.361 0.639
L10-L14 Bullous disorders
0.000 0.361 0.639
H43.0 Vitreous prolapse
0.000 0.361 0.639
J30-J39 Other diseases of upper respiratory tract
0.000 0.362 0.638
K90.9 Intestinal malabsorption, unspecified
0.000 0.362 0.638
H34.0 Transient retinal artery occlusion
0.000 0.363 0.637
K51.0 Ulcerative (chronic) enterocolitis
0.636 0.364 0.000
G82 Paraplegia and tetraplegia
0.636 0.364 0.000
J33.8 Other polyp of sinus
0.000 0.364 0.636
H40-H42 Glaucoma
0.000 0.366 0.634
M34.1 CR(E)ST syndrome
0.000 0.366 0.634
M24.11 Other articular cartilage disorders (Shoulder region)
0.000 0.367 0.633
M00-M03 Infectious arthropathies
0.000 0.367 0.632
M31 Other necrotising vasculopathies
0.000 0.369 0.631
M21 Other acquired deformities of limbs
0.000 0.371 0.629
M94 Other disorders of cartilage
0.000 0.372 0.628
K51.1 Ulcerative (chronic) ileocolitis
0.628 0.372 0.000
G57.5 Tarsal tunnel syndrome
0.627 0.372 0.000
J43.2 Centrilobular emphysema
0.000 0.376 0.624
K86.2 Cyst of pancreas
0.000 0.377 0.623
D59.8 Other acquired haemolytic anaemias
0.623 0.377 0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.623 0.377 0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.623 0.377 0.000
D59.4 Other nonautoimmune haemolytic anaemias
0.623 0.377 0.000
D59.3 Haemolytic-uraemic syndrome
0.623 0.377 0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.623 0.377 0.000
D59.0 Drug-induced autoimmune haemolytic anaemia
0.623 0.377 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.378 0.622
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.382 0.618
K82.0 Obstruction of gallbladder
0.000 0.383 0.617
K91.5 Postcholecystectomy syndrome
0.000 0.384 0.616
Chapter VIII Diseases of the ear and mastoid process
0.000 0.385 0.615
K77 Liver disorders in diseases classified elsewhere
0.000 0.386 0.614
K71 Toxic liver disease
0.000 0.386 0.614
G57.9 Mononeuropathy of lower limb, unspecified
0.612 0.388 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.388 0.612
D58 Other hereditary haemolytic anaemias
0.610 0.389 0.001
J45.8 Mixed asthma
0.000 0.391 0.609
M24.6 Ankylosis of joint
0.000 0.395 0.605
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.395 0.604
M14.4 Arthropathy in amyloidosis
0.000 0.395 0.604
M14.3 Lipoid dermatoarthritis
0.000 0.395 0.604
M14.2 Diabetic arthropathy
0.000 0.395 0.604
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.395 0.604
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.395 0.604
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.396 0.604
D52.8 Other folate deficiency anaemias
0.604 0.396 0.000
D52.1 Drug-induced folate deficiency anaemia
0.604 0.396 0.000
D52.0 Dietary folate deficiency anaemia
0.604 0.396 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.602 0.397 0.001
D53 Other nutritional anaemias
0.602 0.397 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.399 0.601
G55.0 Nerve root and plexus compressions in neoplastic disease
0.600 0.399 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.401 0.599
G25.1 Drug-induced tremor
0.597 0.403 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.000 0.403 0.597
G58 Other mononeuropathies
0.595 0.403 0.001
H60-H62 Diseases of external ear
0.000 0.403 0.597
E03.1 Congenital hypothyroidism without goitre
0.000 0.404 0.596
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.404 0.596
K81.8 Other cholecystitis
0.000 0.404 0.596
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.406 0.594
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.406 0.594
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.406 0.594
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.406 0.594
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.406 0.594
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.406 0.594
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.406 0.594
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.406 0.594
K73.9 Chronic hepatitis, unspecified
0.000 0.406 0.594
G83.9 Paralytic syndrome, unspecified
0.591 0.408 0.000
J41 Simple and mucopurulent chronic bronchitis
0.000 0.411 0.588
K75.2 Nonspecific reactive hepatitis
0.000 0.413 0.587
K75.1 Phlebitis of portal vein
0.000 0.413 0.587
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.413 0.587
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.413 0.587
M30.2 Juvenile polyarteritis
0.000 0.413 0.587
D68.0 Von Willebrand's disease
0.587 0.413 0.000
M35.8 Other specified systemic involvement of connective tissue
0.000 0.415 0.585
K74.6 Other and unspecified cirrhosis of liver
0.000 0.416 0.584
G82.1 Spastic paraplegia
0.584 0.416 0.000
G83.1 Monoplegia of lower limb
0.581 0.419 0.000
E05.5 Thyroid crisis or storm
0.000 0.420 0.580
E05.4 Thyrotoxicosis factitia
0.000 0.420 0.580
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.420 0.580
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.420 0.580
J86.9 Pyothorax without fistula
0.000 0.420 0.580
H31 Other disorders of choroid
0.000 0.421 0.578
M65 Synovitis and tenosynovitis
0.000 0.421 0.579
M13 Other arthritis
0.000 0.422 0.578
M32 Systemic lupus erythematosus
0.000 0.422 0.578
K85 Acute pancreatitis
0.000 0.422 0.578
K86.3 Pseudocyst of pancreas
0.000 0.423 0.577
M24.4 Recurrent dislocation and subluxation of joint
0.000 0.423 0.577
J85 Abscess of lung and mediastinum
0.000 0.424 0.575
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.426 0.574
M60-M63 Disorders of muscles
0.000 0.427 0.572
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.428 0.572
G25.9 Extrapyramidal and movement disorder, unspecified
0.572 0.428 0.000
J43.8 Other emphysema
0.000 0.430 0.570
G81.9 Hemiplegia, unspecified
0.569 0.431 0.000
J45.0 Predominantly allergic asthma
0.000 0.431 0.569
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.432 0.568
J43.1 Panlobular emphysema
0.000 0.433 0.567
J43.0 MacLeod's syndrome
0.000 0.433 0.567
H61 Other disorders of external ear
0.000 0.434 0.566
K50-K52 Noninfective enteritis and colitis
0.106 0.434 0.460
H10-H13 Disorders of conjunctiva
0.000 0.435 0.565
E07.8 Other specified disorders of thyroid
0.000 0.438 0.562
K90.8 Other intestinal malabsorption
0.000 0.438 0.562
G30-G32 Other degenerative diseases of the nervous system
0.557 0.440 0.003
E07.1 Dyshormogenetic goitre
0.000 0.440 0.560
E07.0 Hypersecretion of calcitonin
0.000 0.440 0.560
K72.9 Hepatic failure, unspecified
0.000 0.441 0.559
G83.4 Cauda equina syndrome
0.559 0.441 0.000
M86-M90 Other osteopathies
0.000 0.442 0.558
G23 Other degenerative diseases of basal ganglia
0.557 0.442 0.001
G21 Secondary Parkinsonism
0.557 0.442 0.001
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.557 0.442 0.001
G22 Parkinsonism in diseases classified elsewhere
0.557 0.442 0.001
G25.2 Other specified forms of tremor
0.557 0.442 0.000
K75.8 Other specified inflammatory liver diseases
0.000 0.445 0.554
M33 Dermatopolymyositis
0.000 0.446 0.554
M24.9 Joint derangement, unspecified
0.000 0.446 0.554
M24.7 Protrusio acetabuli
0.000 0.446 0.554
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.448 0.552
G25.0 Essential tremor
0.552 0.448 0.000
K72.0 Acute and subacute hepatic failure
0.000 0.448 0.552
M34.9 Systemic sclerosis, unspecified
0.000 0.450 0.550
H30.9 Chorioretinal inflammation, unspecified
0.000 0.450 0.550
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.450 0.550
J86.0 Pyothorax with fistula
0.000 0.452 0.548
G50 Disorders of trigeminal nerve
0.546 0.453 0.001
J33.0 Polyp of nasal cavity
0.000 0.453 0.547
G80 Infantile cerebral palsy
0.546 0.453 0.001
G25.3 Myoclonus
0.545 0.454 0.000
D84.1 Defects in the complement system
0.545 0.454 0.000
G57.0 Lesion of sciatic nerve
0.544 0.456 0.000
M94.2 Chondromalacia
0.000 0.461 0.539
G25.6 Drug-induced tics and other tics of organic origin
0.536 0.464 0.000
G25.5 Other chorea
0.536 0.464 0.000
G25.4 Drug-induced chorea
0.536 0.464 0.000
M94.8 Other specified disorders of cartilage
0.000 0.465 0.535
M24.5 Contracture of joint
0.000 0.466 0.534
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.466 0.534
M34.0 Progressive systemic sclerosis
0.000 0.466 0.534
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.467 0.533
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.001 0.468 0.532

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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