TreeWAS – Variant ID: rs2395909

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R21 Rash and other nonspecific skin eruption	0.000	0.828	0.172
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.878	0.122
R23 Other skin changes	0.000	0.879	0.121
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.000	0.881	0.119
R23.1 Pallor	0.000	0.882	0.118
R23.4 Changes in skin texture	0.000	0.889	0.111
R23.2 Flushing	0.000	0.903	0.097
R23.0 Cyanosis	0.000	0.914	0.085
R23.3 Spontaneous ecchymoses	0.000	0.915	0.085
R23.8 Other and unspecified skin changes	0.000	0.917	0.083
O72.1 Other immediate postpartum haemorrhage	0.000	0.965	0.035
R20 Disturbances of skin sensation	0.000	0.965	0.035
Z89.5 Acquired absence of leg at or below knee	0.000	0.970	0.030
R20.3 Hyperaesthesia	0.000	0.971	0.029
R20.0 Anaesthesia of skin	0.000	0.973	0.027
O72 Postpartum haemorrhage	0.000	0.976	0.024
R20.1 Hypoaesthesia of skin	0.000	0.976	0.023
Z89 Acquired absence of limb	0.000	0.976	0.024
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.978	0.022
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.978	0.022
I42.0 Dilated cardiomyopathy	0.000	0.979	0.021
Z89.6 Acquired absence of leg above knee	0.000	0.979	0.021
Z89.9 Acquired absence of limb, unspecified	0.000	0.980	0.020
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.980	0.020
Z89.4 Acquired absence of foot and ankle	0.000	0.980	0.020
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.981	0.019
O72.0 Third-stage haemorrhage	0.000	0.982	0.018
I42 Cardiomyopathy	0.000	0.982	0.018
O72.3 Postpartum coagulation defects	0.000	0.983	0.017
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.983	0.017
Z89.1 Acquired absence of hand and wrist	0.000	0.983	0.017
R22.1 Localised swelling, mass and lump, neck	0.000	0.983	0.017
R22.0 Localised swelling, mass and lump, head	0.000	0.983	0.017
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.983	0.016
I42.2 Other hypertrophic cardiomyopathy	0.000	0.984	0.016
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.984	0.016
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.984	0.016
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.986	0.014
Z89.2 Acquired absence of upper limb above wrist	0.000	0.987	0.013
I42.4 Endocardial fibroelastosis	0.000	0.987	0.013
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.987	0.013
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.987	0.013
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.987	0.013
I42.5 Other restrictive cardiomyopathy	0.000	0.988	0.012
I42.6 Alcoholic cardiomyopathy	0.000	0.988	0.012
I25.5 Ischaemic cardiomyopathy	0.000	0.988	0.012
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.990	0.010
I25 Chronic ischaemic heart disease	0.000	0.990	0.010
I42.8 Other cardiomyopathies	0.000	0.990	0.010
R22.2 Localised swelling, mass and lump, trunk	0.000	0.991	0.009
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.991	0.009
M13.91 Arthritis, unspecified (Shoulder region)	0.009	0.991	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.991	0.009
I25.3 Aneurysm of heart	0.000	0.991	0.009
T88 Other complications of surgical and medical care, not elsewhere classified	0.000	0.991	0.009
T88.4 Failed or difficult intubation	0.000	0.991	0.009
I25.6 Silent myocardial ischaemia	0.000	0.992	0.008
D12.7 Rectosigmoid junction	0.008	0.992	0.000
I25.1 Atherosclerotic heart disease	0.000	0.992	0.008
G70.0 Myasthenia gravis	0.008	0.992	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.992	0.008
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.993	0.007
L05.9 Pilonidal cyst without abscess	0.000	0.993	0.007
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.993	0.007
G71.1 Myotonic disorders	0.007	0.993	0.000
T88.2 Shock due to anaesthesia	0.000	0.993	0.007
G71 Primary disorders of muscles	0.007	0.993	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.000	0.993	0.006
T88.1 Other complications following immunisation, not elsewhere classified	0.000	0.993	0.006
T88.0 Infection following immunisation	0.000	0.993	0.006
G70 Myasthenia gravis and other myoneural disorders	0.006	0.993	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.994	0.006
T88.9 Complication of surgical and medical care, unspecified	0.000	0.994	0.006
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.006	0.994	0.000
G71.0 Muscular dystrophy	0.006	0.994	0.000
G70-G73 Diseases of myoneural junction and muscle	0.006	0.994	0.000
N92.4 Excessive bleeding in the premenopausal period	0.000	0.994	0.006
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.000	0.995	0.005
G71.3 Mitochondrial myopathy, not elsewhere classified	0.005	0.995	0.000
G47.9 Sleep disorder, unspecified	0.005	0.995	0.000
S92.30 Fracture of metatarsal bone (closed)	0.005	0.995	0.000
D22.5 Melanocytic naevi of trunk	0.000	0.995	0.005
G71.9 Primary disorder of muscle, unspecified	0.005	0.995	0.000
G71.8 Other primary disorders of muscles	0.005	0.995	0.000
G71.2 Congenital myopathies	0.005	0.995	0.000
T88.5 Other complications of anaesthesia	0.000	0.995	0.005
I25.4 Coronary artery aneurysm	0.000	0.995	0.005
G70.2 Congenital and developmental myasthenia	0.005	0.995	0.000
G70.1 Toxic myoneural disorders	0.005	0.995	0.000
G72 Other myopathies	0.005	0.995	0.000
G70.9 Myoneural disorder, unspecified	0.005	0.995	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.005	0.995	0.000
G70.8 Other specified myoneural disorders	0.004	0.995	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.004	0.995	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.995	0.005
R46.8 Other symptoms and signs involving appearance and behaviour	0.004	0.996	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.004	0.996	0.000
G72.1 Alcoholic myopathy	0.004	0.996	0.000
G72.9 Myopathy, unspecified	0.004	0.996	0.000
L05 Pilonidal cyst	0.000	0.996	0.004
K22.5 Diverticulum of oesophagus, acquired	0.000	0.996	0.004
Q61.2 Polycystic kidney, adult type	0.000	0.996	0.004
G72.3 Periodic paralysis	0.004	0.996	0.000
G72.2 Myopathy due to other toxic agents	0.004	0.996	0.000
S27.0 Traumatic pneumothorax	0.004	0.996	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.996	0.004
Q61.9 Cystic kidney disease, unspecified	0.000	0.996	0.004
G73.7 Myopathy other diseases classified elsewhere	0.003	0.996	0.000
S92.3 Fracture of metatarsal bone	0.004	0.996	0.000
G73.6 Myopathy in metabolic diseases	0.003	0.996	0.000
G73.5 Myopathy in endocrine diseases	0.003	0.996	0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.003	0.996	0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.003	0.996	0.000
G73.2 Other myasthenic syndromes in neoplastic disease	0.003	0.996	0.000
G73.1 Eaton-Lambert syndrome	0.003	0.996	0.000
G73.0 Myasthenic syndromes in endocrine diseases	0.003	0.996	0.000
G72.8 Other specified myopathies	0.003	0.997	0.000
K55.9 Vascular disorder of intestine, unspecified	0.000	0.997	0.003
S42.00 Fracture of clavicle (closed)	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.003	0.997	0.000
G72.0 Drug-induced myopathy	0.003	0.997	0.000
M89.9 Disorder of bone, unspecified	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.997	0.003
Q61 Cystic kidney disease	0.000	0.997	0.003
R46 Symptoms and signs involving appearance and behaviour	0.003	0.997	0.000
R09.0 Asphyxia	0.003	0.997	0.000
D37.0 Lip, oral cavity and pharynx	0.003	0.997	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.003	0.997	0.000
L05.0 Pilonidal cyst with abscess	0.000	0.997	0.003
R46.4 Slowness and poor responsiveness	0.003	0.997	0.000
R46.2 Strange and inexplicable behaviour	0.003	0.997	0.000
R20.2 Paraesthesia of skin	0.000	0.997	0.003
M89.55 Osteolysis (Pelvic region and thigh)	0.003	0.997	0.000
I65.2 Occlusion and stenosis of carotid artery	0.000	0.997	0.003
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.997	0.003
S92.31 Fracture of metatarsal bone (open)	0.003	0.997	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M89.0 Algoneurodystrophy	0.003	0.997	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.003	0.997	0.000
M89.5 Osteolysis	0.003	0.997	0.000
G25.3 Myoclonus	0.003	0.997	0.000
G40.9 Epilepsy, unspecified	0.000	0.997	0.003
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.002	0.997	0.000
G25 Other extrapyramidal and movement disorders	0.003	0.997	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.002	0.997	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.997	0.003
M89.92 Disorder of bone, unspecified (Upper arm)	0.002	0.997	0.000
Q61.8 Other cystic kidney diseases	0.000	0.997	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.997	0.002
M89.94 Disorder of bone, unspecified (Hand)	0.003	0.997	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.997	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.997	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.997	0.000
G25.1 Drug-induced tremor	0.002	0.997	0.000
D16.3 Short bones of lower limb	0.000	0.997	0.003
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.002	0.997	0.000
R46.6 Undue concern and preoccupation with stressful events	0.002	0.997	0.000
R46.5 Suspiciousness and marked evasiveness	0.002	0.997	0.000
R46.3 Overactivity	0.002	0.997	0.000
R46.1 Bizarre personal appearance	0.002	0.997	0.000
M89 Other disorders of bone	0.003	0.997	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.002	0.997	0.000
S27 Injury of other and unspecified intrathoracic organs	0.002	0.997	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.998	0.002
Z93.5 Cystostomy status	0.002	0.998	0.000
M94.88 Other specified disorders of cartilage (Other)	0.002	0.998	0.000
R46.0 Very low level of personal hygiene	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.000	0.998	0.002
R01.1 Cardiac murmur, unspecified	0.000	0.998	0.002
S22.20 Fracture of sternum (closed)	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
S92.4 Fracture of great toe	0.002	0.998	0.000
W19.4 Street and highway	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.002	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.000	0.998	0.002
M89.91 Disorder of bone, unspecified (Shoulder region)	0.002	0.998	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.002	0.998	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.998	0.002
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
S27.3 Other injuries of lung	0.002	0.998	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.002	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.002	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.002	0.998	0.000
M89.58 Osteolysis (Other)	0.002	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.998	0.000
M89.54 Osteolysis (Hand)	0.002	0.998	0.000
M89.53 Osteolysis (Forearm)	0.002	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.998	0.000
G25.5 Other chorea	0.002	0.998	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.000	0.998	0.002
R16.0 Hepatomegaly, not elsewhere classified	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.002	0.998	0.000
G25.4 Drug-induced chorea	0.002	0.998	0.000
M70.4 Prepatellar bursitis	0.000	0.998	0.002
Z53.9 Procedure not carried out, unspecified reason	0.002	0.998	0.000
M89.98 Disorder of bone, unspecified (Other)	0.002	0.998	0.000
H40.5 Glaucoma secondary to other eye disorders	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.998	0.002
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
H40.0 Glaucoma suspect	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.002	0.998	0.000
M89.2 Other disorders of bone development and growth	0.002	0.998	0.000
M89.1 Epiphyseal arrest	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.000	0.998	0.002
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
S27.9 Injury of unspecified intrathoracic organ	0.002	0.998	0.000
S27.7 Multiple injuries of intrathoracic organs	0.002	0.998	0.000
S27.6 Injury of pleura	0.002	0.998	0.000
S27.5 Injury of thoracic trachea	0.002	0.998	0.000
S27.4 Injury of bronchus	0.002	0.998	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.998	0.002
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
D48.5 Skin	0.002	0.998	0.000
R47.1 Dysarthria and anarthria	0.000	0.998	0.002
B44.9 Aspergillosis, unspecified	0.000	0.998	0.002
G54.0 Brachial plexus disorders	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.998	0.002
M94.8 Other specified disorders of cartilage	0.002	0.998	0.000
I67.2 Cerebral atherosclerosis	0.000	0.998	0.002
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.000	0.998	0.002
S92.5 Fracture of other toe	0.002	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.002	0.998	0.000
L03.2 Cellulitis of face	0.000	0.998	0.002
S27.1 Traumatic haemothorax	0.002	0.998	0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.002	0.998	0.000
M89.3 Hypertrophy of bone	0.002	0.998	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.002	0.998	0.000
G54.4 Lumbosacral root disorders, not elsewhere classified	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.002	0.998	0.000
G25.2 Other specified forms of tremor	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.000	0.998	0.002
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
T79.7 Traumatic subcutaneous emphysema	0.002	0.998	0.000
F40.2 Specific (isolated) phobias	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.998	0.002
M94.81 Other specified disorders of cartilage (Shoulder region)	0.002	0.998	0.000
G54 Nerve root and plexus disorders	0.002	0.998	0.000
M70.49 Prepatellar bursitis-Site unspec	0.000	0.998	0.002
M70.48 Prepatellar bursitis-Other	0.000	0.998	0.002
M70.47 Prepatellar bursitis-Ankle/Foot	0.000	0.998	0.002
M70.45 Prepatellar bursitis-Pelvic/Thigh	0.000	0.998	0.002
M70.44 Prepatellar bursitis-Hand	0.000	0.998	0.002
M70.43 Prepatellar bursitis-Forearm	0.000	0.998	0.002
M70.42 Prepatellar bursitis-Upper arm	0.000	0.998	0.002
M70.41 Prepatellar bursitis-Shldr region	0.000	0.998	0.002
M70.40 Prepatellar bursitis-Mult sites	0.000	0.998	0.002
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.002	0.998	0.000
N05.9 Unspecified	0.000	0.998	0.002
N61 Inflammatory disorders of breast	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.002	0.998	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.998	0.002
Z01.5 Diagnostic skin and sensitisation tests	0.000	0.998	0.002
M89.19 Epiphyseal arrest (Site unspecified)	0.002	0.998	0.000
M89.18 Epiphyseal arrest (Other)	0.002	0.998	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.002	0.998	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.002	0.998	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.002	0.998	0.000
M89.14 Epiphyseal arrest (Hand)	0.002	0.998	0.000
M89.13 Epiphyseal arrest (Forearm)	0.002	0.998	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.002	0.998	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.002	0.998	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.002	0.998	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.002	0.998	0.000
M89.28 Other disorders of bone development and growth (Other)	0.002	0.998	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.002	0.998	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.002	0.998	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.002	0.998	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.002	0.998	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.002	0.998	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.002	0.998	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.002	0.998	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.002	0.998	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.002	0.998	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.002	0.998	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.002	0.998	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.002	0.998	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.002	0.998	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.002	0.998	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.002	0.998	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.002	0.998	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.002	0.998	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.998	0.002
I65.1 Occlusion and stenosis of basilar artery	0.000	0.998	0.002
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.998	0.002
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.002	0.998	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.002	0.998	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.002	0.998	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.002	0.998	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.002	0.998	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.002	0.998	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.002	0.998	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.002	0.998	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.002	0.998	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.002	0.998	0.000
I25.2 Old myocardial infarction	0.000	0.998	0.002
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.998	0.002
M94.84 Other specified disorders of cartilage (Hand)	0.002	0.998	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.002	0.998	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.002	0.998	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.002	0.998	0.000
G54.8 Other nerve root and plexus disorders	0.002	0.998	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.001	0.998	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.998	0.002
S22.2 Fracture of sternum	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.998	0.002
Q60-Q64 Congenital malformations of the urinary system	0.000	0.998	0.002
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.001	0.998	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.001	0.998	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.001	0.998	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.001	0.998	0.000
M89.34 Hypertrophy of bone (Hand)	0.001	0.998	0.000
M89.33 Hypertrophy of bone (Forearm)	0.001	0.998	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.001	0.998	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.001	0.998	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.001	0.998	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.001	0.998	0.000
S42.0 Fracture of clavicle	0.002	0.998	0.000
X62.9 Unspecified place	0.000	0.998	0.002
M76.67 Achilles tendinitis (Ankle and foot)	0.000	0.998	0.002
S92.71 Multiple fractures of foot (open)	0.001	0.998	0.000
G25.0 Essential tremor	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.000	0.998	0.001
Q76.8 Other congenital malformations of bony thorax	0.000	0.998	0.001
Q76.7 Congenital malformation of sternum	0.000	0.998	0.001
Q76.6 Other congenital malformations of ribs	0.000	0.998	0.001
Q76.3 Congenital scoliosis due to congenital bony malformation	0.000	0.998	0.001
Q76.2 Congenital spondylolisthesis	0.000	0.998	0.001
S92.51 Fracture of other toe (open)	0.001	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.000	0.998	0.002
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
M79.54 Residual foreign body in soft tissue (Hand)	0.000	0.998	0.002
G54.7 Phantom limb syndrome without pain	0.001	0.998	0.000
G54.5 Neuralgic amyotrophy	0.001	0.998	0.000
G54.3 Thoracic root disorders, not elsewhere classified	0.001	0.998	0.000
G54.1 Lumbosacral plexus disorders	0.001	0.998	0.000
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
Q74 Other congenital malformations of limb(s)	0.000	0.998	0.002
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.000	0.998	0.001
Q76.1 Klippel-Feil syndrome	0.000	0.998	0.001
C48.2 Peritoneum, unspecified	0.000	0.998	0.002
L03.8 Cellulitis of other sites	0.000	0.998	0.002
L00-L08 Infections of the skin and subcutaneous tissue	0.000	0.998	0.002
M89.37 Hypertrophy of bone (Ankle and foot)	0.001	0.998	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.998	0.002
Q62.5 Duplication of ureter	0.000	0.998	0.001
R00.8 Other and unspecified abnormalities of heart beat	0.000	0.998	0.002
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.998	0.001
Q68 Other congenital musculoskeletal deformities	0.000	0.998	0.001
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.000	0.998	0.002
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.001	0.998	0.000
H21.0 Hyphaema	0.000	0.998	0.001
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.001	0.998	0.000
Q54.9 Hypospadias, unspecified	0.000	0.998	0.001
Q76.5 Cervical rib	0.000	0.998	0.001
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.998	0.001
M43.19 Spondylolisthesis (Site unspecified)	0.001	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.001	0.998	0.000
G54.2 Cervical root disorders, not elsewhere classified	0.001	0.998	0.000
L04 Acute lymphadenitis	0.000	0.998	0.001
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.001	0.998	0.000
S22.21 Fracture of sternum (open)	0.001	0.998	0.000
L04.2 Acute lymphadenitis of upper limb	0.000	0.998	0.001
Y42.0 Glucocorticoids and synthetic analogs	0.001	0.998	0.000
L01 Impetigo	0.000	0.998	0.001
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.001	0.999	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
S42.01 Fracture of clavicle (open)	0.001	0.999	0.000
L04.9 Acute lymphadenitis, unspecified	0.000	0.999	0.001
S92.70 Multiple fractures of foot (closed)	0.001	0.999	0.000
H10.9 Conjunctivitis, unspecified	0.000	0.999	0.001
M18.1 Other primary arthrosis of first carpometacarpal joint	0.001	0.999	0.000
Q25.4 Other congenital malformations of aorta	0.000	0.999	0.001
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.999	0.000
Q65 Congenital deformities of hip	0.000	0.999	0.001
L01.0 Impetigo [any organism] [any site]	0.000	0.999	0.001
Q66.7 Pes cavus	0.000	0.999	0.001
Q74.9 Unspecified congenital malformation of limb(s)	0.000	0.999	0.001
Q74.8 Other specified congenital malformations of limb(s)	0.000	0.999	0.001
Q74.3 Arthrogryposis multiplex congenita	0.000	0.999	0.001
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.001	0.999	0.000
G54.6 Phantom limb syndrome with pain	0.001	0.999	0.000
H21.2 Degeneration of iris and ciliary body	0.000	0.999	0.001
Q65.1 Congenital dislocation of hip, bilateral	0.000	0.999	0.001
Q78.0 Osteogenesis imperfecta	0.000	0.999	0.001
I67 Other cerebrovascular diseases	0.000	0.999	0.001
Q78 Other osteochondrodysplasias	0.000	0.999	0.001
M11.26 Other chondrocalcinosis (Lower leg)	0.001	0.999	0.000
B44.1 Other pulmonary aspergillosis	0.000	0.999	0.001
Q68.5 Congenital bowing of long bones of leg, unspecified	0.000	0.999	0.001
Q68.4 Congenital bowing of tibia and fibula	0.000	0.999	0.001
Q68.3 Congenital bowing of femur	0.000	0.999	0.001
Q68.2 Congenital deformity of knee	0.000	0.999	0.001
Q68.1 Congenital deformity of hand	0.000	0.999	0.001
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.000	0.999	0.001
Y85.0 Sequelae of motor-vehicle accident	0.001	0.999	0.000
L00 Staphylococcal scalded skin syndrome	0.000	0.999	0.001
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.001	0.999	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.001	0.999	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.001	0.999	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.001	0.999	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.001	0.999	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.001	0.999	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.001	0.999	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.001	0.999	0.000
Q43.8 Other specified congenital malformations of intestine	0.001	0.999	0.000
Q60.6 Potter's syndrome	0.000	0.999	0.001
Q60.5 Renal hypoplasia, unspecified	0.000	0.999	0.001
Q60.4 Renal hypoplasia, bilateral	0.000	0.999	0.001
Q60.1 Renal agenesis, bilateral	0.000	0.999	0.001
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.999	0.001
Q62.6 Malposition of ureter	0.000	0.999	0.001
Q62.4 Agenesis of ureter	0.000	0.999	0.001
Q62.0 Congenital hydronephrosis	0.000	0.999	0.001
Q65.2 Congenital dislocation of hip, unspecified	0.000	0.999	0.001
Q75 Other congenital malformations of skull and face bones	0.000	0.999	0.001
Q73 Reduction defects of unspecified limb	0.000	0.999	0.001
Q72 Reduction defects of lower limb	0.000	0.999	0.001
Q71 Reduction defects of upper limb	0.000	0.999	0.001
Q70 Syndactyly	0.000	0.999	0.001
Q69 Polydactyly	0.000	0.999	0.001
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.999	0.001
L04.1 Acute lymphadenitis of trunk	0.000	0.999	0.001
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.999	0.001
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.999	0.001
Q62.2 Congenital megaloureter	0.000	0.999	0.001
Q62.1 Atresia and stenosis of ureter	0.000	0.999	0.001
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.999	0.001
L03.1 Cellulitis of other parts of limb	0.000	0.999	0.001
L04.8 Acute lymphadenitis of other sites	0.000	0.999	0.001
L04.3 Acute lymphadenitis of lower limb	0.000	0.999	0.001
Q66.0 Talipes equinovarus	0.000	0.999	0.001
S21.1 Open wound of front wall of thorax	0.001	0.999	0.000
L03 Cellulitis	0.000	0.999	0.001
N89 Other noninflammatory disorders of vagina	0.000	0.999	0.001
L01.1 Impetiginisation of other dermatoses	0.000	0.999	0.001
Q60.3 Renal hypoplasia, unilateral	0.000	0.999	0.001
Q62.8 Other congenital malformations of ureter	0.000	0.999	0.001
Q65.9 Congenital deformity of hip, unspecified	0.000	0.999	0.001
S92.0 Fracture of calcaneus	0.001	0.999	0.000
X59.3 Sports and athletics area	0.000	0.999	0.001
H21 Other disorders of iris and ciliary body	0.000	0.999	0.001
Q66 Congenital deformities of feet	0.000	0.999	0.001
G11.4 Hereditary spastic paraplegia	0.000	0.999	0.001
H21.4 Pupillary membranes	0.000	0.999	0.001
M35.3 Polymyalgia rheumatica	0.001	0.999	0.000
M89.8 Other specified disorders of bone	0.001	0.999	0.000
Q65.6 Unstable hip	0.000	0.999	0.001
Q65.5 Congenital subluxation of hip, unspecified	0.000	0.999	0.001
Q65.4 Congenital subluxation of hip, bilateral	0.000	0.999	0.001
Q65.3 Congenital subluxation of hip, unilateral	0.000	0.999	0.001
S21.0 Open wound of breast	0.001	0.999	0.000
U81.0 Vancomycin resistant agent	0.001	0.999	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.000	0.999	0.001
S21 Open wound of thorax	0.001	0.999	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.001	0.999	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.001	0.999	0.000
I67.5 Moyamoya disease	0.000	0.999	0.001
I67.3 Progressive vascular leukoencephalopathy	0.000	0.999	0.001
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.999	0.001
N89.4 Leukoplakia of vagina	0.000	0.999	0.001
Q65.0 Congenital dislocation of hip, unilateral	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations