TreeWAS – Variant ID: rs2412970

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.209	0.791
E03.8 Other specified hypothyroidism	0.000	0.328	0.672
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.363	0.637
E03.1 Congenital hypothyroidism without goitre	0.000	0.369	0.631
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.409	0.591
E03.5 Myxoedema coma	0.000	0.433	0.567
E03.4 Atrophy of thyroid (acquired)	0.000	0.433	0.567
E03.3 Postinfectious hypothyroidism	0.000	0.433	0.567
E00-E07 Disorders of thyroid gland	0.000	0.846	0.154
E06 Thyroiditis	0.000	0.868	0.131
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.882	0.118
E06.3 Autoimmune thyroiditis	0.000	0.882	0.118
E07 Other disorders of thyroid	0.000	0.884	0.116
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.889	0.111
E00 Congenital iodine-deficiency syndrome	0.000	0.889	0.111
E06.5 Other chronic thyroiditis	0.000	0.901	0.099
E06.9 Thyroiditis, unspecified	0.000	0.902	0.098
E07.9 Disorder of thyroid, unspecified	0.000	0.902	0.098
E06.4 Drug-induced thyroiditis	0.000	0.905	0.094
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.905	0.094
E06.0 Acute thyroiditis	0.000	0.905	0.094
E07.1 Dyshormogenetic goitre	0.000	0.916	0.083
E07.0 Hypersecretion of calcitonin	0.000	0.916	0.083
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.920	0.080
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.920	0.080
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.920	0.080
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.920	0.080
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.920	0.080
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.920	0.080
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.920	0.080
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.920	0.080
E06.1 Subacute thyroiditis	0.000	0.923	0.076
S22.40 Multiple fractures of ribs (closed)	0.000	0.930	0.070
E07.8 Other specified disorders of thyroid	0.000	0.934	0.066
E04 Other non-toxic goitre	0.000	0.958	0.042
E10.3 With ophthalmic complications	0.000	0.958	0.042
E10 Insulin-dependent diabetes mellitus	0.000	0.958	0.042
E10.1 With ketoacidosis	0.000	0.959	0.041
E10.2 With renal complications	0.000	0.962	0.038
E10.4 With neurological complications	0.000	0.963	0.037
S22.4 Multiple fractures of ribs	0.000	0.966	0.034
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.034	0.966	0.000
E10.9 Without complications	0.000	0.968	0.032
E04.9 Non-toxic goitre, unspecified	0.000	0.968	0.032
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.031	0.969	0.000
E04.8 Other specified non-toxic goitre	0.000	0.969	0.030
E10.7 With multiple complications	0.000	0.970	0.030
E10.8 With unspecified complications	0.000	0.971	0.029
E10.6 With other specified complications	0.000	0.971	0.028
H83.0 Labyrinthitis	0.000	0.972	0.028
I80 Phlebitis and thrombophlebitis	0.027	0.973	0.000
E10.5 With peripheral circulatory complications	0.000	0.974	0.026
S22.41 Multiple fractures of ribs (open)	0.000	0.976	0.024
E04.0 Non-toxic diffuse goitre	0.000	0.976	0.024
E10.0 With coma	0.000	0.979	0.020
I80.8 Phlebitis and thrombophlebitis of other sites	0.018	0.982	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.982	0.018
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.018	0.982	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.984	0.016
S80.9 Superficial injury of lower leg, unspecified	0.000	0.984	0.016
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.015	0.985	0.000
S82.40 Fracture of fibula alone (closed)	0.000	0.985	0.015
E04.1 Non-toxic single thyroid nodule	0.000	0.987	0.013
S82.4 Fracture of fibula alone	0.000	0.987	0.013
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.013	0.987	0.000
D50.8 Other iron deficiency anaemias	0.000	0.987	0.013
S82 Fracture of lower leg, including ankle	0.000	0.987	0.013
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.987	0.012
S82.2 Fracture of shaft of tibia	0.000	0.988	0.012
E05.5 Thyroid crisis or storm	0.000	0.988	0.012
E05.4 Thyrotoxicosis factitia	0.000	0.988	0.012
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.988	0.012
S82.20 Fracture of shaft of tibia (closed)	0.000	0.988	0.012
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.012	0.988	0.000
S82.7 Multiple fractures of lower leg	0.000	0.988	0.012
S82.70 Multiple fractures of lower leg (closed)	0.000	0.989	0.011
E10-E14 Diabetes mellitus	0.000	0.989	0.011
S82.6 Fracture of lateral malleolus	0.000	0.989	0.011
S82.0 Fracture of patella	0.000	0.989	0.011
S82.21 Fracture of shaft of tibia (open)	0.000	0.990	0.010
S82.01 Fracture of patella (open)	0.000	0.990	0.010
H83 Other diseases of inner ear	0.000	0.990	0.010
Z45.2 Adjustment and management of vascular access device	0.000	0.990	0.010
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.990	0.010
S82.9 Fracture of lower leg, part unspecified	0.000	0.990	0.010
S82.41 Fracture of fibula alone (open)	0.000	0.990	0.010
M21.3 Wrist or foot drop (acquired)	0.010	0.990	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.990	0.010
S80 Superficial injury of lower leg	0.000	0.990	0.009
E05.8 Other thyrotoxicosis	0.000	0.991	0.009
S82.60 Fracture of lateral malleolus (closed)	0.000	0.991	0.009
Y40.0 Penicillins	0.000	0.991	0.009
S80-S89 Injuries to the knee and lower leg	0.000	0.991	0.009
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.991	0.009
S81 Open wound of lower leg	0.000	0.991	0.009
S81.8 Open wound of other parts of lower leg	0.000	0.991	0.009
M21 Other acquired deformities of limbs	0.009	0.991	0.000
S82.61 Fracture of lateral malleolus (open)	0.000	0.991	0.009
S82.71 Multiple fractures of lower leg (open)	0.000	0.991	0.008
M21.8 Other specified acquired deformities of limbs	0.008	0.992	0.000
S82.5 Fracture of medial malleolus	0.000	0.992	0.008
S81.7 Multiple open wounds of lower leg	0.000	0.992	0.008
E12 Malnutrition-related diabetes mellitus	0.000	0.992	0.008
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.992	0.008
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.992	0.008
H83.2 Labyrinthine dysfunction	0.000	0.992	0.008
S81.9 Open wound of lower leg, part unspecified	0.000	0.992	0.008
H83.1 Labyrinthine fistula	0.000	0.992	0.007
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.008	0.992	0.000
M21.0 Valgus deformity, not elsewhere classified	0.007	0.992	0.000
H83.8 Other specified diseases of inner ear	0.000	0.993	0.007
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.993	0.007
N18.5 Chronic kidney disease, stage 5	0.000	0.993	0.007
M21.4 Flat foot [pes planus] (acquired)	0.007	0.993	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.007	0.993	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.007	0.993	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.007	0.993	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.007	0.993	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.007	0.993	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.007	0.993	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.007	0.993	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.007	0.993	0.000
M21.6 Other acquired deformities of ankle and foot	0.007	0.993	0.000
H83.9 Disease of inner ear, unspecified	0.000	0.993	0.007
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.007	0.993	0.000
S87 Crushing injury of lower leg	0.000	0.993	0.007
M21.9 Acquired deformity of limb, unspecified	0.007	0.993	0.000
S88 Traumatic amputation of lower leg	0.000	0.993	0.007
S85 Injury of blood vessels at lower leg level	0.000	0.993	0.007
S84 Injury of nerves at lower leg level	0.000	0.993	0.007
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.007	0.993	0.000
B37.8 Candidiasis of other sites	0.000	0.993	0.007
M21.33 Wrist or foot drop (acquired) (Forearm)	0.006	0.993	0.000
S82.00 Fracture of patella (closed)	0.000	0.993	0.007
M21.1 Varus deformity, not elsewhere classified	0.007	0.993	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.007	0.993	0.000
M21.2 Flexion deformity	0.006	0.993	0.000
H83.3 Noise effects on inner ear	0.000	0.993	0.006
S80.0 Contusion of knee	0.000	0.994	0.006
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.006	0.994	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.006	0.994	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.006	0.994	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.006	0.994	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.006	0.994	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.006	0.994	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.006	0.994	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.006	0.994	0.000
F03 Unspecified dementia	0.000	0.994	0.006
E13 Other specified diabetes mellitus	0.000	0.994	0.006
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.006	0.994	0.000
E12.9 Without complications	0.000	0.994	0.006
E12.8 With unspecified complications	0.000	0.994	0.006
E12.7 With multiple complications	0.000	0.994	0.006
E12.6 With other specified complications	0.000	0.994	0.006
E12.5 With peripheral circulatory complications	0.000	0.994	0.006
E12.4 With neurological complications	0.000	0.994	0.006
E12.3 With ophthalmic complications	0.000	0.994	0.006
E12.2 With renal complications	0.000	0.994	0.006
E12.1 With ketoacidosis	0.000	0.994	0.006
E12.0 With coma	0.000	0.994	0.006
M21.7 Unequal limb length (acquired)	0.006	0.994	0.000
S80.7 Multiple superficial injuries of lower leg	0.000	0.994	0.006
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.006	0.994	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.994	0.006
S22.8 Fracture of other parts of bony thorax	0.000	0.994	0.006
S82.51 Fracture of medial malleolus (open)	0.000	0.994	0.006
S89 Other and unspecified injuries of lower leg	0.000	0.994	0.006
M21.26 Flexion deformity (Lower leg)	0.006	0.994	0.000
Q61.3 Polycystic kidney, unspecified	0.006	0.994	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.994	0.006
S86 Injury of muscle and tendon at lower leg level	0.000	0.994	0.006
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.005	0.994	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.005	0.994	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.005	0.994	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.005	0.994	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.005	0.994	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.005	0.994	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.005	0.994	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.005	0.994	0.000
S22.5 Flail chest	0.000	0.994	0.006
S82.1 Fracture of upper end of tibia	0.000	0.994	0.006
S82.8 Fractures of other parts of lower leg	0.000	0.994	0.006
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.005	0.994	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.005	0.994	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.005	0.994	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.005	0.994	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.005	0.994	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.005	0.994	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.005	0.994	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.005	0.994	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.005	0.994	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.005	0.994	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.005	0.995	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.005	0.995	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.005	0.995	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.005	0.995	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.005	0.995	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.005	0.995	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.005	0.995	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.005	0.995	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.005	0.995	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.005	0.995	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.995	0.005
S22.1 Multiple fractures of thoracic spine	0.000	0.995	0.005
S22.3 Fracture of rib	0.000	0.995	0.005
S80.8 Other superficial injuries of lower leg	0.000	0.995	0.005
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.995	0.005
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.005	0.995	0.000
S22.2 Fracture of sternum	0.000	0.995	0.005
M21.94 Acquired deformity of limb, unspecified (Hand)	0.005	0.995	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.995	0.005
Z49.1 Extracorporeal dialysis	0.000	0.995	0.005
E14 Unspecified diabetes mellitus	0.000	0.995	0.005
S87.0 Crushing injury of knee	0.000	0.995	0.005
N02.8 Other	0.000	0.995	0.005
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.005	0.995	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.005	0.995	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.005	0.995	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.005	0.995	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.005	0.995	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.005	0.995	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.005	0.995	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.995	0.005
S82.3 Fracture of lower end of tibia	0.000	0.995	0.005
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.995	0.005
S84.8 Injury of other nerves at lower leg level	0.000	0.995	0.005
S84.7 Injury of multiple nerves at lower leg level	0.000	0.995	0.005
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.995	0.005
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.995	0.005
S84.0 Injury of tibial nerve at lower leg level	0.000	0.995	0.005
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.995	0.005
S85.8 Injury of other blood vessels at lower leg level	0.000	0.995	0.005
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.995	0.005
S85.5 Injury of popliteal vein	0.000	0.995	0.005
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.995	0.005
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.995	0.005
S85.2 Injury of peroneal artery	0.000	0.995	0.005
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.995	0.005
S85.0 Injury of popliteal artery	0.000	0.995	0.005
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.995	0.005
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.995	0.005
S88.0 Traumatic amputation at knee level	0.000	0.995	0.005
J31.0 Chronic rhinitis	0.005	0.995	0.000
H44.2 Degenerative myopia	0.000	0.995	0.005
L90.0 Lichen sclerosus et atrophicus	0.005	0.995	0.000
Q61 Cystic kidney disease	0.005	0.995	0.000
M21.22 Flexion deformity (Upper arm)	0.005	0.995	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.005	0.995	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.005	0.995	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.005	0.995	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.005	0.995	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
E14.2 Withrenal complications	0.000	0.995	0.005
M21.29 Flexion deformity (Site unspecified)	0.005	0.995	0.000
M21.28 Flexion deformity (Other)	0.005	0.995	0.000
M21.23 Flexion deformity (Forearm)	0.005	0.995	0.000
M21.21 Flexion deformity (Shoulder region)	0.005	0.995	0.000
M21.20 Flexion deformity (Multiple sites)	0.005	0.995	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.005	0.995	0.000
E40-E46 Malnutrition	0.000	0.995	0.005
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.995	0.005
E13.8 With unspecified complications	0.000	0.995	0.005
E13.7 With multiple complications	0.000	0.995	0.005
E13.6 With other specified complications	0.000	0.995	0.005
E13.5 With peripheral circulatory complications	0.000	0.995	0.005
E13.4 With neurological complications	0.000	0.995	0.005
E13.3 With ophthalmic complications	0.000	0.995	0.005
E13.2 With renal complications	0.000	0.995	0.005
E13.1 With ketoacidosis	0.000	0.995	0.005
E13.0 With coma	0.000	0.995	0.005
E14.1 With ketoacidosis	0.000	0.995	0.005
M21.79 Unequal limb length (acquired) (Site unspecified)	0.004	0.995	0.000
M21.78 Unequal limb length (acquired)-Other	0.004	0.995	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.004	0.995	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.004	0.995	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.004	0.995	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.004	0.995	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.004	0.995	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.995	0.005
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.004	0.995	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.004	0.995	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.004	0.995	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.004	0.995	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.004	0.995	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.004	0.995	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.004	0.995	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.004	0.995	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.995	0.004
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.995	0.004
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.995	0.004
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.995	0.004
K25.7 Chronic without haemorrhage or perforation	0.000	0.995	0.005
Q61.2 Polycystic kidney, adult type	0.005	0.995	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.995	0.004
S89.8 Other specified injuries of lower leg	0.000	0.995	0.004
M21.76 Unequal limb length (acquired) (Lower leg)	0.004	0.995	0.000
H44 Disorders of globe	0.000	0.995	0.005
S89.7 Multiple injuries of lower leg	0.000	0.995	0.004
S89.1 Other specified injuries of lower leg	0.000	0.995	0.004
S89.0 Multiple injuries of lower leg	0.000	0.995	0.004
H44.0 Purulent endophthalmitis	0.000	0.996	0.004
H44.4 Hypotony of eye	0.000	0.996	0.004
E15 Nondiabetic hypoglycaemic coma	0.000	0.996	0.004
Q61.0 Congenital single renal cyst	0.004	0.996	0.000
S86.0 Injury of Achilles tendon	0.000	0.996	0.004
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.996	0.004
S22.51 Flail chest (open)	0.000	0.996	0.004
S82.86 Maisonneuve's fracture	0.000	0.996	0.004
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.996	0.004
M41.9 Scoliosis, unspecified	0.000	0.996	0.004
E14.5 With peripheral circulatory complications	0.000	0.996	0.004
S22.01 Fracture of thoracic vertebra (open)	0.000	0.996	0.004
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.996	0.004
S22.31 Fracture of rib (open)	0.000	0.996	0.004
M46.46 Discitis, unspecified (Lumbar region)	0.000	0.996	0.004
S22.21 Fracture of sternum (open)	0.000	0.996	0.004
Q61.5 Medullary cystic kidney	0.004	0.996	0.000
M21.27 Flexion deformity (Ankle and foot)	0.004	0.996	0.000
E14.7 With multiple complications	0.000	0.996	0.004
E14.0 With coma	0.000	0.996	0.004
Q61.9 Cystic kidney disease, unspecified	0.004	0.996	0.000
H44.8 Other disorders of globe	0.000	0.996	0.004
M21.73 Unequal limb length (acquired) (Forearm)	0.004	0.996	0.000
Q61.8 Other cystic kidney diseases	0.004	0.996	0.000
Q61.1 Polycystic kidney, infantile type	0.004	0.996	0.000
S22.50 Flail chest (closed)	0.000	0.996	0.004
Q61.4 Renal dysplasia	0.004	0.996	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.996	0.004
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.996	0.003
E45 Retarded development following protein-energy malnutrition	0.000	0.996	0.003
E43 Unspecified severe protein-energy malnutrition	0.000	0.996	0.003
E42 Marasmic kwashiorkor	0.000	0.996	0.003
E41 Nutritional marasmus	0.000	0.996	0.003
E40 Kwashiorkor	0.000	0.996	0.003
R76.8 Other specified abnormal immunological findings in serum	0.004	0.996	0.000
E14.6 With other specified complications	0.000	0.996	0.004
H44.5 Degenerated conditions of globe	0.000	0.996	0.004
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.996	0.004
E14.8 With unspecified complications	0.000	0.996	0.003
M21.24 Flexion deformity (Hand)	0.003	0.996	0.000
E14.4 With neurological complications	0.000	0.996	0.003
R52.1 Chronic intractable pain	0.000	0.996	0.004
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.996	0.003
H44.3 Other degenerative disorders of globe	0.000	0.996	0.003
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.996	0.004
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.997	0.003
N18.0 End-stage renal disease	0.000	0.997	0.003
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.997	0.003
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.997	0.003
S82.11 Fracture of upper end of tibia (open)	0.000	0.997	0.003
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
S86.00 Unspecified injury of Achilles tendon	0.000	0.997	0.003
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.003	0.997	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.997	0.003
S22.30 Fracture of rib (closed)	0.000	0.997	0.003
J35.1 Hypertrophy of tonsils	0.000	0.997	0.003
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.997	0.003
E65-E68 Obesity and other hyperalimentation	0.000	0.997	0.003
S82.81 Fractures of other parts of lower leg (open)	0.000	0.997	0.003
E16 Other disorders of pancreatic internal secretion	0.000	0.997	0.003
S89.9 Unspecified injury of lower leg	0.000	0.997	0.003
H61.8 Other specified disorders of external ear	0.003	0.997	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.997	0.003
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.997	0.003
S22.20 Fracture of sternum (closed)	0.000	0.997	0.003
E50-E64 Other nutritional deficiencies	0.000	0.997	0.003
C22.1 Intrahepatic bile duct carcinoma	0.003	0.997	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.997	0.003
Z99.8 Dependence on other enabling machines and devices	0.000	0.997	0.003
H44.9 Disorder of globe, unspecified	0.000	0.997	0.003
Z99.3 Dependence on wheelchair	0.000	0.997	0.003
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.997	0.003
C85.1 B-cell lymphoma, unspecified	0.000	0.997	0.003
H44.1 Other endophthalmitis	0.000	0.997	0.003
S14.3 Injury of brachial plexus	0.000	0.997	0.003
Z99.2 Dependence on renal dialysis	0.000	0.997	0.003
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.997	0.003
K52.8 Other specified non-infective gastro-enteritis and colitis	0.003	0.997	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.997	0.003
E44.0 Moderate protein-energy malnutrition	0.000	0.997	0.003
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.003	0.997	0.000
E16.1 Other hypoglycaemia	0.000	0.997	0.003
S14.1 Other and unspecified injuries of cervical spinal cord	0.000	0.997	0.003
I12.9 Hypertensive renal disease without renal failure	0.000	0.997	0.003
S81.0 Open wound of knee	0.000	0.997	0.003
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.997	0.003
R76.0 Raised antibody titer	0.003	0.997	0.000
M79.18 Myalgia (Other)	0.000	0.997	0.003
E51 Thiamine deficiency	0.000	0.997	0.003
E67 Other hyperalimentation	0.000	0.997	0.003
E68 Sequelae of hyperalimentation	0.000	0.997	0.003
S82.31 Fracture of lower end of tibia (open)	0.000	0.997	0.002
E13.9 Without complications	0.000	0.997	0.002
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.997	0.003
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.997	0.003
E16.4 Abnormal secretion of gastrin	0.000	0.997	0.003
E16.3 Increased secretion of glucagon	0.000	0.997	0.003
E56 Other vitamin deficiencies	0.000	0.997	0.003
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.000	0.997	0.003
E58 Dietary calcium deficiency	0.000	0.997	0.003
S14 Injury of nerves and spinal cord at neck level	0.000	0.997	0.003
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.997	0.003
K25.4 Chronic or unspecified with haemorrhage	0.000	0.997	0.003
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.997	0.002
E63 Other nutritional deficiencies	0.000	0.997	0.002
E50 Vitamin A deficiency	0.000	0.997	0.002
E60 Dietary zinc deficiency	0.000	0.997	0.002
E59 Dietary selenium deficiency	0.000	0.997	0.002
E52 Niacin deficiency [pellagra]	0.000	0.997	0.002
N18.8 Other chronic renal failure	0.000	0.997	0.003
R76 Other abnormal immunological findings in serum	0.003	0.997	0.000
M85.0 Fibrous dysplasia (monostotic)	0.003	0.997	0.000
K25 Gastric ulcer	0.000	0.997	0.003
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
C18.9 Colon, unspecified	0.000	0.997	0.003
M85.66 Other cyst of bone (Lower leg)	0.002	0.997	0.000
N18 Chronic renal failure	0.000	0.997	0.003
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
N41.0 Acute prostatitis	0.002	0.998	0.000
Q64.4 Malformation of urachus	0.002	0.998	0.000
E14.3 With ophthalmic complications	0.000	0.998	0.002
M85.6 Other cyst of bone	0.002	0.998	0.000
E55 Vitamin D deficiency	0.000	0.998	0.002
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.002	0.998	0.000
N02 Recurrent and persistent haematuria	0.000	0.998	0.002
Q63.2 Ectopic kidney	0.002	0.998	0.000
Y77.3 Surgical instruments, materials and devices (including sutures)	0.000	0.998	0.002
B25.9 Cytomegaloviral disease, unspecified	0.000	0.998	0.002
E51.2 Wernicke's encephalopathy	0.000	0.998	0.002
K25.0 Acute with haemorrhage	0.000	0.998	0.002
Z94.0 Kidney transplant status	0.000	0.998	0.002
S82.10 Fracture of upper end of tibia (closed)	0.000	0.998	0.002
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.998	0.002
H66.9 Otitis media, unspecified	0.000	0.998	0.002
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
K25.5 Chronic or unspecified with perforation	0.000	0.998	0.002
S82.30 Fracture of lower end of tibia (closed)	0.000	0.998	0.002
D16.4 Bones of skull and face	0.000	0.998	0.002
E56.1 Deficiency of vitamin K	0.000	0.998	0.002
E54 Ascorbic acid deficiency	0.000	0.998	0.002
E51.9 Thiamine deficiency, unspecified	0.000	0.998	0.002
E51.8 Other manifestations of thiamine deficiency	0.000	0.998	0.002
E51.1 Beriberi	0.000	0.998	0.002
E67.8 Other specified hyperalimentation	0.000	0.998	0.002
E67.3 Hypervitaminosis D	0.000	0.998	0.002
E67.2 Megavitamin-B6 syndrome	0.000	0.998	0.002
E67.1 Hypercarotenaemia	0.000	0.998	0.002
E67.0 Hypervitaminosis A	0.000	0.998	0.002
E56.9 Vitamin deficiency, unspecified	0.000	0.998	0.002
E56.8 Deficiency of other vitamins	0.000	0.998	0.002
E56.0 Deficiency of vitamin E	0.000	0.998	0.002
N95.2 Postmenopausal atrophic vaginitis	0.002	0.998	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.002	0.998	0.000
Z99.4 Dependence on artificial heart	0.000	0.998	0.002
H66.3 Other chronic suppurative otitis media	0.000	0.998	0.002
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
S14.6 Injury of other and unspecified nerves of neck	0.000	0.998	0.002
S14.5 Injury of cervical sympathetic nerves	0.000	0.998	0.002
S14.4 Injury of peripheral nerves of neck	0.000	0.998	0.002
S14.2 Injury of nerve root of cervical spine	0.000	0.998	0.002
S14.0 Concussion and oedema of cervical spinal cord	0.000	0.998	0.002
Z49 Care involving dialysis	0.000	0.998	0.002
E50.9 Vitamin A deficiency, unspecified	0.000	0.998	0.002
E50.8 Other manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.998	0.002
E50.5 Vitamin A deficiency with night blindness	0.000	0.998	0.002
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.998	0.002
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.998	0.002
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.998	0.002
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.998	0.002
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.998	0.002
E63.9 Nutritional deficiency, unspecified	0.000	0.998	0.002
E63.8 Other specified nutritional deficiencies	0.000	0.998	0.002
E63.1 Imbalance of constituents of food intake	0.000	0.998	0.002
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.998	0.002
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.998	0.002
E64.8 Sequelae of other nutritional deficiencies	0.000	0.998	0.002
E64.3 Sequelae of rickets	0.000	0.998	0.002
E64.2 Sequelae of vitamin C deficiency	0.000	0.998	0.002
E64.1 Sequelae of vitamin A deficiency	0.000	0.998	0.002
E64.0 Sequelae of protein-energy malnutrition	0.000	0.998	0.002
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.002	0.998	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.002	0.998	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.002	0.998	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.002	0.998	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.002	0.998	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.002	0.998	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations