TreeWAS – Variant ID: rs2427345

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E04.9 Non-toxic goitre, unspecified	0.291	0.709	0.000
E04 Other non-toxic goitre	0.201	0.799	0.000
E05.9 Thyrotoxicosis, unspecified	0.177	0.823	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.174	0.826	0.000
E00-E07 Disorders of thyroid gland	0.173	0.827	0.000
E04.2 Non-toxic multinodular goitre	0.159	0.841	0.000
E04.8 Other specified non-toxic goitre	0.144	0.856	0.000
E28.2 Polycystic ovarian syndrome	0.144	0.856	0.000
E28 Ovarian dysfunction	0.131	0.869	0.000
E06 Thyroiditis	0.130	0.870	0.000
E04.0 Non-toxic diffuse goitre	0.130	0.870	0.000
E05.8 Other thyrotoxicosis	0.126	0.874	0.000
E20-E35 Disorders of other endocrine glands	0.125	0.875	0.000
E05.5 Thyroid crisis or storm	0.125	0.875	0.000
E05.4 Thyrotoxicosis factitia	0.125	0.875	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.125	0.875	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.125	0.875	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.124	0.876	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.124	0.876	0.000
E00 Congenital iodine-deficiency syndrome	0.124	0.876	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.124	0.876	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.123	0.877	0.000
E40-E46 Malnutrition	0.116	0.884	0.000
E26 Hyperaldosteronism	0.113	0.887	0.000
E06.9 Thyroiditis, unspecified	0.113	0.887	0.000
E46 Unspecified protein-energy malnutrition	0.111	0.889	0.000
E22 Hyperfunction of pituitary gland	0.108	0.891	0.000
E26.0 Primary hyperaldosteronism	0.104	0.896	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.103	0.897	0.000
E34 Other endocrine disorders	0.100	0.900	0.000
E06.5 Other chronic thyroiditis	0.095	0.904	0.000
E20 Hypoparathyroidism	0.095	0.905	0.000
E28.9 Ovarian dysfunction, unspecified	0.094	0.906	0.000
E28.8 Other ovarian dysfunction	0.094	0.906	0.000
E28.1 Androgen excess	0.094	0.906	0.000
E28.0 Oestrogen excess	0.094	0.906	0.000
E06.4 Drug-induced thyroiditis	0.094	0.906	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.094	0.906	0.000
E06.1 Subacute thyroiditis	0.094	0.906	0.000
E06.0 Acute thyroiditis	0.094	0.906	0.000
E25 Adrenogenital disorders	0.090	0.909	0.000
E31 Polyglandular dysfunction	0.090	0.910	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.090	0.910	0.000
E32 Diseases of thymus	0.090	0.910	0.000
E30 Disorders of puberty, not elsewhere classified	0.090	0.910	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.089	0.911	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.089	0.911	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.089	0.911	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.089	0.911	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.089	0.911	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.089	0.911	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.089	0.911	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.089	0.911	0.000
E50-E64 Other nutritional deficiencies	0.089	0.911	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.083	0.917	0.000
E45 Retarded development following protein-energy malnutrition	0.083	0.917	0.000
E43 Unspecified severe protein-energy malnutrition	0.083	0.917	0.000
E42 Marasmic kwashiorkor	0.083	0.917	0.000
E41 Nutritional marasmus	0.083	0.917	0.000
E40 Kwashiorkor	0.083	0.917	0.000
E34.0 Carcinoid syndrome	0.082	0.918	0.000
E26.8 Other hyperaldosteronism	0.081	0.919	0.000
E26.1 Secondary hyperaldosteronism	0.081	0.919	0.000
E61 Deficiency of other nutrient elements	0.081	0.919	0.000
E29 Testicular dysfunction	0.081	0.919	0.000
E24 Cushing's syndrome	0.081	0.919	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.080	0.920	0.000
E23 Hypofunction and other disorders of pituitary gland	0.080	0.920	0.000
E26.9 Hyperaldosteronism, unspecified	0.080	0.920	0.000
E34.9 Endocrine disorder, unspecified	0.079	0.921	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.078	0.922	0.000
E22.8 Other hyperfunction of pituitary gland	0.078	0.922	0.000
E61.1 Iron deficiency	0.078	0.922	0.000
E07 Other disorders of thyroid	0.078	0.922	0.000
E28.3 Primary ovarian failure	0.076	0.924	0.000
E20.9 Hypoparathyroidism, unspecified	0.073	0.927	0.000
E34.5 Androgen resistance syndrome	0.072	0.928	0.000
E34.4 Constitutional tall stature	0.072	0.928	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.072	0.928	0.000
E34.1 Other hypersecretion of intestinal hormones	0.072	0.928	0.000
E34.3 Short stature, not elsewhere classified	0.072	0.928	0.000
E22.0 Acromegaly and pituitary gigantism	0.072	0.928	0.000
E20.8 Other hypoparathyroidism	0.068	0.932	0.000
E20.1 Pseudohypoparathyroidism	0.068	0.932	0.000
E20.0 Idiopathic hypoparathyroidism	0.068	0.932	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.065	0.934	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.065	0.934	0.000
E31.0 Autoimmune polyglandular failure	0.065	0.935	0.000
E25.9 Adrenogenital disorder, unspecified	0.065	0.935	0.000
E25.8 Other adrenogenital disorders	0.065	0.935	0.000
E31.9 Polyglandular dysfunction, unspecified	0.065	0.935	0.000
E31.8 Other polyglandular dysfunction	0.065	0.935	0.000
E31.1 Polyglandular hyperfunction	0.065	0.935	0.000
E30.9 Disorder of puberty, unspecified	0.065	0.935	0.000
E30.8 Other disorders of puberty	0.065	0.935	0.000
E30.1 Precocious puberty	0.065	0.935	0.000
E30.0 Delayed puberty	0.065	0.935	0.000
E32.9 Disease of thymus, unspecified	0.065	0.935	0.000
E32.8 Other diseases of thymus	0.065	0.935	0.000
E32.1 Abscess of thymus	0.065	0.935	0.000
E32.0 Persistent hyperplasia of thymus	0.065	0.935	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.065	0.935	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.065	0.935	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.065	0.935	0.000
E55 Vitamin D deficiency	0.065	0.935	0.000
E24.2 Drug-induced Cushing's syndrome	0.064	0.936	0.000
E06.3 Autoimmune thyroiditis	0.064	0.936	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.064	0.936	0.000
E63 Other nutritional deficiencies	0.064	0.936	0.000
E50 Vitamin A deficiency	0.064	0.936	0.000
E60 Dietary zinc deficiency	0.064	0.936	0.000
E59 Dietary selenium deficiency	0.064	0.936	0.000
E54 Ascorbic acid deficiency	0.064	0.936	0.000
E52 Niacin deficiency [pellagra]	0.064	0.936	0.000
E34.8 Other specified endocrine disorders	0.064	0.936	0.000
E27 Other disorders of adrenal gland	0.064	0.936	0.000
E23.6 Other disorders of pituitary gland	0.063	0.937	0.000
E44.1 Mild protein-energy malnutrition	0.060	0.940	0.000
E44.0 Moderate protein-energy malnutrition	0.060	0.940	0.000
E04.1 Non-toxic single thyroid nodule	0.060	0.940	0.000
E56 Other vitamin deficiencies	0.060	0.940	0.000
E22.1 Hyperprolactinaemia	0.059	0.941	0.000
E58 Dietary calcium deficiency	0.059	0.941	0.000
E61.9 Deficiency of nutrient element, unspecified	0.058	0.942	0.000
E61.8 Deficiency of other specified nutrient elements	0.058	0.942	0.000
E61.7 Deficiency of multiple nutrient elements	0.058	0.942	0.000
E61.6 Vanadium deficiency	0.058	0.942	0.000
E61.5 Molybdenum deficiency	0.058	0.942	0.000
E61.4 Chromium deficiency	0.058	0.942	0.000
E61.3 Manganese deficiency	0.058	0.942	0.000
E61.0 Copper deficiency	0.058	0.942	0.000
E29.9 Testicular dysfunction, unspecified	0.058	0.942	0.000
E29.8 Other testicular dysfunction	0.058	0.942	0.000
E29.0 Testicular hyperfunction	0.058	0.942	0.000
E24.8 Other Cushing's syndrome	0.058	0.942	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.058	0.942	0.000
E24.3 Ectopic ACTH syndrome	0.058	0.942	0.000
E24.1 Nelson's syndrome	0.058	0.942	0.000
E23.7 Disorder of pituitary gland, unspecified	0.058	0.942	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.058	0.942	0.000
E23.1 Drug-induced hypopituitarism	0.058	0.942	0.000
E07.1 Dyshormogenetic goitre	0.056	0.944	0.000
E07.0 Hypersecretion of calcitonin	0.056	0.944	0.000
E51 Thiamine deficiency	0.055	0.945	0.000
E27.8 Other specified disorders of adrenal gland	0.050	0.950	0.000
E23.0 Hypopituitarism	0.050	0.950	0.000
E24.0 Pituitary-dependent Cushing's disease	0.049	0.950	0.000
E53 Deficiency of other B group vitamins	0.049	0.951	0.000
E29.1 Testicular hypofunction	0.049	0.951	0.000
E24.9 Cushing's syndrome, unspecified	0.049	0.951	0.000
E27.9 Disorder of adrenal gland, unspecified	0.048	0.952	0.000
E61.2 Magnesium deficiency	0.048	0.952	0.000
E23.2 Diabetes insipidus	0.048	0.952	0.000
E15 Nondiabetic hypoglycaemic coma	0.047	0.953	0.000
E55.9 Vitamin D deficiency, unspecified	0.047	0.953	0.000
E55.0 Rickets, active	0.046	0.953	0.000
E50.9 Vitamin A deficiency, unspecified	0.046	0.954	0.000
E50.8 Other manifestations of vitamin A deficiency	0.046	0.954	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.046	0.954	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.046	0.954	0.000
E50.5 Vitamin A deficiency with night blindness	0.046	0.954	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.046	0.954	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.046	0.954	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.046	0.954	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.046	0.954	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.046	0.954	0.000
E63.9 Nutritional deficiency, unspecified	0.046	0.954	0.000
E63.8 Other specified nutritional deficiencies	0.046	0.954	0.000
E63.1 Imbalance of constituents of food intake	0.046	0.954	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.046	0.954	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.046	0.954	0.000
E64.8 Sequelae of other nutritional deficiencies	0.046	0.954	0.000
E64.3 Sequelae of rickets	0.046	0.954	0.000
E64.2 Sequelae of vitamin C deficiency	0.046	0.954	0.000
E64.1 Sequelae of vitamin A deficiency	0.046	0.954	0.000
E64.0 Sequelae of protein-energy malnutrition	0.046	0.954	0.000
E27.5 Adrenomedullary hyperfunction	0.046	0.954	0.000
E27.0 Other adrenocortical overactivity	0.046	0.954	0.000
M31.6 Other giant cell arteritis	0.045	0.955	0.000
E07.9 Disorder of thyroid, unspecified	0.044	0.956	0.000
E65-E68 Obesity and other hyperalimentation	0.043	0.957	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.043	0.957	0.000
E56.9 Vitamin deficiency, unspecified	0.043	0.957	0.000
E56.8 Deficiency of other vitamins	0.043	0.957	0.000
E56.0 Deficiency of vitamin E	0.043	0.957	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.043	0.957	0.000
E27.2 Addisonian crisis	0.041	0.959	0.000
E10-E14 Diabetes mellitus	0.040	0.960	0.000
E51.9 Thiamine deficiency, unspecified	0.039	0.960	0.000
E51.8 Other manifestations of thiamine deficiency	0.039	0.960	0.000
E51.1 Beriberi	0.039	0.960	0.000
E56.1 Deficiency of vitamin K	0.039	0.961	0.000
E03 Other hypothyroidism	0.038	0.962	0.000
E53.1 Pyridoxine deficiency	0.036	0.964	0.000
E53.0 Riboflavin deficiency	0.036	0.964	0.000
E07.8 Other specified disorders of thyroid	0.034	0.966	0.000
E53.9 Vitamin B deficiency, unspecified	0.032	0.968	0.000
E67 Other hyperalimentation	0.031	0.969	0.000
E68 Sequelae of hyperalimentation	0.031	0.969	0.000
E51.2 Wernicke's encephalopathy	0.030	0.970	0.001
E10 Insulin-dependent diabetes mellitus	0.030	0.970	0.000
E12 Malnutrition-related diabetes mellitus	0.029	0.971	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.029	0.971	0.000
O72.1 Other immediate postpartum haemorrhage	0.000	0.972	0.028
E10.4 With neurological complications	0.028	0.972	0.000
E03.5 Myxoedema coma	0.027	0.973	0.000
E03.4 Atrophy of thyroid (acquired)	0.027	0.973	0.000
E03.3 Postinfectious hypothyroidism	0.027	0.973	0.000
E53.8 Deficiency of other specified B group vitamins	0.027	0.973	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.026	0.973	0.000
E14 Unspecified diabetes mellitus	0.026	0.974	0.000
E03.1 Congenital hypothyroidism without goitre	0.026	0.974	0.000
E10.1 With ketoacidosis	0.026	0.974	0.000
E65 Localised adiposity	0.026	0.974	0.000
O72.0 Third-stage haemorrhage	0.000	0.975	0.025
E10.3 With ophthalmic complications	0.025	0.975	0.000
E13 Other specified diabetes mellitus	0.024	0.975	0.000
E16 Other disorders of pancreatic internal secretion	0.024	0.976	0.000
O72 Postpartum haemorrhage	0.000	0.976	0.024
E14.6 With other specified complications	0.024	0.976	0.000
E10.7 With multiple complications	0.024	0.976	0.000
E10.6 With other specified complications	0.024	0.976	0.000
E27.1 Primary adrenocortical insufficiency	0.023	0.977	0.000
E67.8 Other specified hyperalimentation	0.023	0.977	0.000
E67.3 Hypervitaminosis D	0.023	0.977	0.000
E67.2 Megavitamin-B6 syndrome	0.023	0.977	0.000
E67.1 Hypercarotenaemia	0.023	0.977	0.000
E67.0 Hypervitaminosis A	0.023	0.977	0.000
E10.8 With unspecified complications	0.022	0.978	0.000
E14.5 With peripheral circulatory complications	0.022	0.978	0.000
E12.9 Without complications	0.021	0.979	0.000
E12.8 With unspecified complications	0.021	0.979	0.000
E12.7 With multiple complications	0.021	0.979	0.000
E12.6 With other specified complications	0.021	0.979	0.000
E12.5 With peripheral circulatory complications	0.021	0.979	0.000
E12.4 With neurological complications	0.021	0.979	0.000
E12.3 With ophthalmic complications	0.021	0.979	0.000
E12.2 With renal complications	0.021	0.979	0.000
E12.1 With ketoacidosis	0.021	0.979	0.000
E12.0 With coma	0.021	0.979	0.000
E10.2 With renal complications	0.020	0.980	0.000
E14.3 With ophthalmic complications	0.020	0.980	0.000
E14.8 With unspecified complications	0.020	0.980	0.000
E13.3 With ophthalmic complications	0.019	0.980	0.000
E14.7 With multiple complications	0.019	0.981	0.000
E14.0 With coma	0.019	0.981	0.000
E14.4 With neurological complications	0.018	0.982	0.000
E14.1 With ketoacidosis	0.018	0.982	0.000
E13.8 With unspecified complications	0.018	0.982	0.000
E13.7 With multiple complications	0.018	0.982	0.000
E13.6 With other specified complications	0.018	0.982	0.000
E13.5 With peripheral circulatory complications	0.018	0.982	0.000
E13.4 With neurological complications	0.018	0.982	0.000
E13.2 With renal complications	0.018	0.982	0.000
E13.1 With ketoacidosis	0.018	0.982	0.000
E13.0 With coma	0.018	0.982	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.018	0.982	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.018	0.982	0.000
E16.4 Abnormal secretion of gastrin	0.018	0.982	0.000
E16.3 Increased secretion of glucagon	0.018	0.982	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.017	0.982	0.000
O72.3 Postpartum coagulation defects	0.000	0.983	0.017
E16.1 Other hypoglycaemia	0.017	0.983	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.016	0.984	0.000
E10.0 With coma	0.015	0.985	0.000
Z97.4 Presence of external hearing-aid	0.000	0.985	0.015
E14.2 Withrenal complications	0.014	0.985	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.986	0.014
E10.5 With peripheral circulatory complications	0.013	0.987	0.000
E21.4 Other specified disorders of parathyroid gland	0.012	0.988	0.000
E03.8 Other specified hypothyroidism	0.012	0.988	0.001
E21.2 Other hyperparathyroidism	0.012	0.988	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.011	0.988	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.012	0.988	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.011	0.989	0.000
M31 Other necrotising vasculopathies	0.010	0.990	0.000
E13.9 Without complications	0.009	0.991	0.000
K02.9 Dental caries, unspecified	0.009	0.991	0.000
M31.8 Other specified necrotising vasculopathies	0.008	0.992	0.000
M31.0 Hypersensitivity angiitis	0.008	0.992	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.008	0.992	0.000
M31.2 Lethal midline granuloma	0.008	0.992	0.000
Z03.4 Observation for suspected myocardial infarction	0.000	0.992	0.008
M31.7 Microscopic polyangiitis	0.007	0.993	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.007	0.993	0.000
N70.1 Chronic salpingitis and oophoritis	0.007	0.993	0.000
M31.9 Necrotising vasculopathy, unspecified	0.007	0.993	0.000
M31.1 Thrombotic microangiopathy	0.006	0.993	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.993	0.007
D22.5 Melanocytic naevi of trunk	0.006	0.994	0.000
O04.4 Incomplete, without complication	0.006	0.994	0.000
M31.3 Wegener's granulomatosis	0.005	0.995	0.000
C15.5 Lower third of oesophagus	0.000	0.995	0.005
W02.9 Unspecified place	0.005	0.995	0.000
N70 Salpingitis and oophoritis	0.005	0.995	0.000
E21.0 Primary hyperparathyroidism	0.005	0.995	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.005	0.995	0.000
E14.9 Without complications	0.005	0.995	0.000
R06.2 Wheezing	0.000	0.995	0.005
K46 Unspecified abdominal hernia	0.005	0.995	0.000
E66 Obesity	0.004	0.996	0.000
N70.0 Acute salpingitis and oophoritis	0.004	0.996	0.000
O04 Medical abortion	0.004	0.996	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
C67.2 Lateral wall of bladder	0.004	0.996	0.000
K09.2 Other cysts of jaw	0.004	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
K02 Dental caries	0.004	0.996	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.003	0.996	0.000
K09 Cysts of oral region, not elsewhere classified	0.003	0.997	0.000
C67.4 Posterior wall of bladder	0.003	0.997	0.000
E66.1 Drug-induced obesity	0.003	0.997	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.003	0.997	0.000
K09.9 Cyst of oral region, unspecified	0.003	0.997	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.003	0.997	0.000
C67.6 Ureteric orifice	0.003	0.997	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.003	0.997	0.000
O04.9 Complete or unspecified, without complication	0.003	0.997	0.000
O04.7 Complete or unspecified, complicated by embolism	0.003	0.997	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.003	0.997	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.003	0.997	0.000
O04.3 Incomplete, with other and unspecified complications	0.003	0.997	0.000
O04.2 Incomplete, complicated by embolism	0.003	0.997	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.003	0.997	0.000
C48.2 Peritoneum, unspecified	0.003	0.997	0.000
K02.1 Caries of dentin	0.003	0.997	0.000
C67 Malignant neoplasm of bladder	0.003	0.997	0.000
Y85.0 Sequelae of motor-vehicle accident	0.003	0.997	0.000
N48.0 Leukoplakia of penis	0.000	0.997	0.003
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.997	0.003
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.997	0.003
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.003	0.997	0.000
N81.3 Complete uterovaginal prolapse	0.000	0.997	0.003
E21.3 Hyperparathyroidism, unspecified	0.003	0.997	0.000
K70.3 Alcoholic cirrhosis of liver	0.003	0.997	0.000
C48.1 Specified parts of peritoneum	0.003	0.997	0.000
E66.0 Obesity due to excess calories	0.003	0.997	0.000
C67.3 Anterior wall of bladder	0.003	0.997	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.003	0.997	0.000
K02.5 Caries with pulp exposure	0.003	0.997	0.000
K02.4 Odontoclasia	0.003	0.997	0.000
K02.3 Arrested dental caries	0.003	0.997	0.000
K02.2 Caries of cementum	0.003	0.997	0.000
K02.0 Caries limited to enamel	0.003	0.997	0.000
E11 Non-insulin-dependent diabetes mellitus	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
K09.0 Developmental odontogenic cysts	0.003	0.997	0.000
E11.7 With multiple complications	0.003	0.997	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.997	0.003
C67.1 Dome of bladder	0.003	0.997	0.000
N76.4 Abscess of vulva	0.000	0.997	0.003
N76.0 Acute vaginitis	0.000	0.997	0.003
C67.8 Overlapping lesion of bladder	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.003	0.997	0.000
C67.7 Urachus	0.002	0.997	0.000
E11.8 With unspecified complications	0.002	0.997	0.000
N76.2 Acute vulvitis	0.000	0.997	0.003
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.997	0.002
M25.86 Other specified joint disorders (Lower leg)	0.000	0.997	0.002
N76 Other inflammation of vagina and vulva	0.000	0.998	0.002
H40.9 Glaucoma, unspecified	0.002	0.998	0.000
C48.0 Retroperitoneum	0.002	0.998	0.000
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.998	0.002
O62.1 Secondary uterine inertia	0.000	0.998	0.002
O70.2 Third degree perineal laceration during delivery	0.000	0.998	0.002
K59.4 Anal spasm	0.002	0.998	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.002	0.998	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.002	0.998	0.000
R79.0 Abnormal level of blood mineral	0.002	0.998	0.000
N76.8 Other specified inflammation of vagina and vulva	0.000	0.998	0.002
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
N76.1 Subacute and chronic vaginitis	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
K02.8 Other dental caries	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
G44.2 Tension-type headache	0.002	0.998	0.000
Z01.4 Gynaecological examination (general)(routine)	0.000	0.998	0.002
S51.9 Open wound of forearm, part unspecified	0.002	0.998	0.000
C67.5 Bladder neck	0.002	0.998	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
G95.2 Cord compression, unspecified	0.000	0.998	0.002
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.998	0.002
L85.8 Other specified epidermal thickening	0.002	0.998	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.998	0.002
E11.4 With neurological complications	0.002	0.998	0.000
K70.1 Alcoholic hepatitis	0.002	0.998	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.002	0.998	0.000
M70.22 Olecranon bursitis-Upper arm	0.000	0.998	0.002
T11.0 Superficial injury of upper limb, level unspecified	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.002	0.998	0.000
K14.0 Glossitis	0.000	0.998	0.002
N76.6 Ulceration of vulva	0.000	0.998	0.002
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.998	0.002
M47.96 Spondylosis, unspecified (Lumbar region)	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
I72.3 Aneurysm of iliac artery	0.002	0.998	0.000
G44.8 Other specified headache syndromes	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
E11.6 With other specified complications	0.002	0.998	0.000
L85.9 Epidermal thickening, unspecified	0.002	0.998	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.002	0.998	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.998	0.002
N48 Other disorders of penis	0.000	0.998	0.002
C67.0 Trigone of bladder	0.002	0.998	0.000
W02.8 Other specified place	0.002	0.998	0.000
W02.3 Sports and athletics area	0.002	0.998	0.000
W02.7 Farm	0.002	0.998	0.000
W02.6 Industrial and construction area	0.002	0.998	0.000
W02.5 Trade and service area	0.002	0.998	0.000
W02.4 Street and highway	0.002	0.998	0.000
W02.2 School, other institution and public administrative area	0.002	0.998	0.000
W02.1 Residential institution	0.002	0.998	0.000
W02.0 Home	0.002	0.998	0.000
Y85 Sequelae of transport accidents	0.002	0.998	0.000
C17.2 Ileum	0.002	0.998	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.002	0.998	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.002	0.998	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.002	0.998	0.000
N76.5 Ulceration of vagina	0.000	0.998	0.002
N48.9 Disorder of penis, unspecified	0.000	0.998	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
O62.3 Precipitate labour	0.000	0.998	0.002
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.998	0.002
C49.4 Connective and soft tissue of abdomen	0.002	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.002	0.998	0.000
O62 Abnormalities of forces of labour	0.000	0.998	0.002
E11.0 With coma	0.002	0.998	0.000
J33.0 Polyp of nasal cavity	0.000	0.998	0.002
O62.2 Other uterine inertia	0.000	0.998	0.002
L85 Other epidermal thickening	0.002	0.998	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
C15.3 Upper third of oesophagus	0.000	0.998	0.002
E11.1 With ketoacidosis	0.002	0.998	0.000
N48.5 Ulcer of penis	0.000	0.998	0.002
S00.1 Contusion of eyelid and periocular area	0.000	0.998	0.002
C15.8 Overlapping lesion of oesophagus	0.000	0.998	0.002
C15.2 Abdominal part of oesophagus	0.000	0.998	0.002
N42.2 Atrophy of prostate	0.000	0.998	0.002
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
N48.8 Other specified disorders of penis	0.000	0.998	0.002
N48.4 Impotence of organic origin	0.000	0.998	0.002
M76.67 Achilles tendinitis (Ankle and foot)	0.002	0.998	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.002	0.998	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
C49.9 Connective and soft tissue, unspecified	0.002	0.998	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.998	0.002
M54.29 Cervicalgia-Site unspe	0.002	0.998	0.000
C15.1 Thoracic part of oesophagus	0.000	0.998	0.002
G44 Other headache syndromes	0.002	0.998	0.000
C49.5 Connective and soft tissue of pelvis	0.002	0.998	0.000
N48.3 Priapism	0.000	0.998	0.002
C18.6 Descending colon	0.002	0.998	0.000
E11.3 With ophthalmic complications	0.002	0.998	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.998	0.002
M21.0 Valgus deformity, not elsewhere classified	0.000	0.998	0.002
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.998	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.002	0.998	0.000
W02.31 Fall involving ice-skates, skis, roller-skates or skateboards; Sports and athletics area; While engaged in leisure activity	0.001	0.998	0.000
W02.30 Fall involving ice-skates, skis, roller-skates or skateboards; Sports and athletics area; While engaged in sports activity	0.001	0.998	0.000
W02.81 Fall involving ice-skates, skis, roller-skates or skateboards; Other specified places; While engaged in leisure activity	0.001	0.998	0.000
K70 Alcoholic liver disease	0.002	0.998	0.000
O66 Other obstructed labour	0.000	0.998	0.002
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.998	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.002	0.998	0.000
O70 Perineal laceration during delivery	0.000	0.998	0.002
M22.4 Chondromalacia patellae	0.002	0.998	0.000
B80 Enterobiasis	0.002	0.998	0.000
N48.1 Balanoposthitis	0.000	0.998	0.002
O62.8 Other abnormalities of forces of labour	0.000	0.998	0.001
C15.4 Middle third of oesophagus	0.000	0.998	0.002
E11.2 With renal complications	0.002	0.998	0.000
G44.1 Vascular headache, not elsewhere classified	0.002	0.998	0.000
H15.8 Other disorders of sclera	0.002	0.998	0.000
L85.3 Xerosis cutis	0.001	0.998	0.000
L85.2 Keratosis punctata (palmaris et plantaris)	0.001	0.998	0.000
L85.0 Acquired ichthyosis	0.001	0.998	0.000
O62.9 Abnormality of forces of labour, unspecified	0.000	0.998	0.001
S61.8 Open wound of other parts of wrist and hand	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.001	0.998	0.000
C46 Kaposi's sarcoma	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations