TreeWAS – Variant ID: rs2455826

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J31.0 Chronic rhinitis	0.080	0.920	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.067	0.933	0.000
J31.1 Chronic nasopharyngitis	0.061	0.939	0.000
J31.2 Chronic pharyngitis	0.059	0.941	0.000
D47.1 Chronic myeloproliferative disease	0.048	0.952	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.045	0.955	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.957	0.043
D47.3 Essential (haemorrhagic) thrombocythaemia	0.040	0.960	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.038	0.962	0.000
D37.4 Colon	0.037	0.963	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.037	0.963	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.037	0.963	0.000
D37.6 Liver, gallbladder and bile ducts	0.035	0.965	0.000
D47.4 Osteomyelofibrosis	0.034	0.966	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.034	0.966	0.000
D47.2 Monoclonal gammopathy	0.033	0.967	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.032	0.967	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.032	0.967	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.032	0.967	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.032	0.968	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.031	0.969	0.000
D45 Polycythaemia vera	0.031	0.969	0.000
D40.0 Prostate	0.028	0.972	0.000
D37.3 Appendix	0.028	0.972	0.000
D37.2 Small intestine	0.028	0.972	0.000
D46 Myelodysplastic syndromes	0.027	0.973	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.027	0.973	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.026	0.973	0.000
D44.9 Endocrine gland, unspecified	0.026	0.974	0.000
D37.7 Other digestive organs	0.025	0.975	0.000
D37.9 Digestive organ, unspecified	0.025	0.975	0.000
D44.4 Craniopharyngeal duct	0.025	0.975	0.000
D40.1 Testis	0.024	0.976	0.000
D44.1 Adrenal gland	0.024	0.976	0.000
D40.7 Other male genital organs	0.023	0.976	0.000
D44.7 Aortic body and other paraganglia	0.023	0.977	0.000
D40.9 Male genital organ, unspecified	0.023	0.977	0.000
D43.0 Brain, supratentorial	0.023	0.977	0.000
D37.1 Stomach	0.023	0.977	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.023	0.977	0.000
D44.0 Thyroid gland	0.023	0.977	0.000
D44.6 Carotid body	0.022	0.978	0.000
D44.5 Pineal gland	0.022	0.978	0.000
D44.2 Parathyroid gland	0.022	0.978	0.000
D46.2 Refractory anaemia with excess of blasts	0.021	0.979	0.000
D37.0 Lip, oral cavity and pharynx	0.020	0.979	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.020	0.980	0.000
D44.8 Pluriglandular involvement	0.020	0.980	0.000
D43.4 Spinal cord	0.020	0.980	0.000
D43.1 Brain, infratentorial	0.020	0.980	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.020	0.980	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.019	0.980	0.000
D46.4 Refractory anaemia, unspecified	0.019	0.980	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.019	0.980	0.000
D46.1 Refractory anaemia with sideroblasts	0.019	0.980	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.019	0.980	0.000
D43.9 Central nervous system, unspecified	0.019	0.980	0.000
D43.7 Other parts of central nervous system	0.019	0.980	0.000
D43.3 Cranial nerves	0.019	0.980	0.000
D46.7 Other myelodysplastic syndromes	0.019	0.981	0.000
D42.9 Meninges, unspecified	0.019	0.981	0.000
D42.1 Spinal meninges	0.019	0.981	0.000
D42.0 Cerebral meninges	0.019	0.981	0.000
D37.5 Rectum	0.019	0.981	0.000
I67 Other cerebrovascular diseases	0.000	0.981	0.019
D44.3 Pituitary gland	0.018	0.982	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.982	0.018
D46.9 Myelodysplastic syndrome, unspecified	0.018	0.982	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.017	0.983	0.000
I67.2 Cerebral atherosclerosis	0.000	0.983	0.017
D38.0 Larynx	0.017	0.983	0.000
D38.6 Respiratory organ, unspecified	0.016	0.983	0.000
D38.5 Other respiratory organs	0.016	0.983	0.000
D38.4 Thymus	0.016	0.983	0.000
D38.3 Mediastinum	0.016	0.983	0.000
D38.2 Pleura	0.016	0.983	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.016	0.984	0.000
D39.9 Female genital organ, unspecified	0.014	0.986	0.000
D39.2 Placenta	0.014	0.986	0.000
D39.7 Other female genital organs	0.014	0.986	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.014	0.986	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.986	0.014
I67.5 Moyamoya disease	0.000	0.986	0.014
I67.4 Hypertensive encephalopathy	0.000	0.986	0.014
I67.3 Progressive vascular leukoencephalopathy	0.000	0.986	0.014
D48.3 Retroperitoneum	0.014	0.986	0.000
D48.0 Bone and articular cartilage	0.013	0.987	0.000
D48.4 Peritoneum	0.012	0.987	0.000
D38.1 Trachea, bronchus and lung	0.012	0.988	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.012	0.988	0.000
D43.2 Brain, unspecified	0.012	0.988	0.000
H50.9 Strabismus, unspecified	0.012	0.988	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.988	0.012
D39.0 Uterus	0.012	0.988	0.000
D41.0 Kidney	0.012	0.988	0.000
D41.9 Urinary organ, unspecified	0.012	0.988	0.000
D41.7 Other urinary organs	0.012	0.988	0.000
D41.3 Urethra	0.012	0.988	0.000
D41.1 Renal pelvis	0.012	0.988	0.000
D39.1 Ovary	0.011	0.988	0.000
D48.6 Breast	0.011	0.988	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.011	0.989	0.000
D48.7 Other specified sites	0.011	0.989	0.000
D48.5 Skin	0.010	0.990	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.010	0.990	0.000
D41.2 Ureter	0.009	0.991	0.000
H50 Other strabismus	0.009	0.991	0.000
H26.4 After-cataract	0.008	0.992	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.008	0.992	0.000
S06 Intracranial injury	0.008	0.992	0.000
S06.2 Diffuse brain injury	0.008	0.992	0.000
H52.0 Hypermetropia	0.008	0.992	0.000
H00.1 Chalazion	0.000	0.992	0.008
S06.5 Traumatic subdural haemorrhage	0.008	0.992	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.007	0.993	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.007	0.993	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.007	0.993	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.007	0.993	0.000
H16.0 Corneal ulcer	0.007	0.993	0.000
H50.1 Divergent concomitant strabismus	0.007	0.993	0.000
S32.50 Fracture of pubis (closed)	0.000	0.993	0.007
D48.1 Connective and other soft tissue	0.007	0.993	0.000
S06.4 Epidural haemorrhage	0.007	0.993	0.000
H50.5 Heterophoria	0.007	0.993	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.993	0.007
H50.6 Mechanical strabismus	0.006	0.993	0.000
H50.3 Intermittent heterotropia	0.006	0.993	0.000
H49 Paralytic strabismus	0.007	0.993	0.000
H50.8 Other specified strabismus	0.006	0.994	0.000
D41.4 Bladder	0.006	0.994	0.000
S06.8 Other intracranial injuries	0.006	0.994	0.000
H52 Disorders of refraction and accommodation	0.006	0.994	0.000
S06.3 Focal brain injury	0.006	0.994	0.000
S06.7 Intracranial injury with prolonged coma	0.006	0.994	0.000
S06.1 Traumatic cerebral oedema	0.006	0.994	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.006	0.994	0.000
H50.2 Vertical strabismus	0.006	0.994	0.000
H50.4 Other and unspecified heterotropia	0.006	0.994	0.000
S06.0 Concussion	0.006	0.994	0.000
H49.2 Sixth [abducent] nerve palsy	0.006	0.994	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.006	0.994	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.006	0.994	0.000
H51 Other disorders of binocular movement	0.006	0.994	0.000
H52.4 Presbyopia	0.006	0.994	0.000
H16 Keratitis	0.006	0.994	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.005	0.994	0.000
H49.8 Other paralytic strabismus	0.005	0.995	0.000
S06.9 Intracranial injury, unspecified	0.005	0.995	0.000
H49.1 Fourth [trochlear] nerve palsy	0.005	0.995	0.000
H50.0 Convergent concomitant strabismus	0.005	0.995	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.005	0.995	0.000
H49.0 Third [oculomotor] nerve palsy	0.005	0.995	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.005	0.995	0.000
E53.8 Deficiency of other specified B group vitamins	0.005	0.995	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.005	0.995	0.000
E87.5 Hyperkalaemia	0.005	0.995	0.000
H49.4 Progressive external ophthalmoplegia	0.005	0.995	0.000
H49.3 Total (external) ophthalmoplegia	0.005	0.995	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.005	0.995	0.000
H52.6 Other disorders of refraction	0.005	0.995	0.000
H52.5 Disorders of accommodation	0.005	0.995	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.005	0.995	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.005	0.995	0.000
H16.4 Corneal neovascularisation	0.005	0.995	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.005	0.995	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.005	0.995	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.005	0.995	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.004	0.995	0.000
K04.8 Radicular cyst	0.005	0.995	0.000
H51.2 Internuclear ophthalmoplegia	0.005	0.995	0.000
H16.9 Keratitis, unspecified	0.005	0.995	0.000
H52.7 Disorder of refraction, unspecified	0.004	0.995	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.004	0.995	0.000
H16.2 Keratoconjunctivitis	0.004	0.995	0.000
S06.01 Concussion (with open intracranial wound)	0.004	0.996	0.000
H52.2 Astigmatism	0.004	0.996	0.000
H51.9 Disorder of binocular movement, unspecified	0.004	0.996	0.000
H51.8 Other specified disorders of binocular movement	0.004	0.996	0.000
H51.1 Convergence insufficiency and excess	0.004	0.996	0.000
H51.0 Palsy of conjugate gaze	0.004	0.996	0.000
I67.1 Cerebral aneurysm, nonruptured	0.000	0.996	0.004
H16.3 Interstitial and deep keratitis	0.004	0.996	0.000
H49.9 Paralytic strabismus, unspecified	0.004	0.996	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.004	0.996	0.000
S32.5 Fracture of pubis	0.000	0.996	0.004
H16.8 Other keratitis	0.004	0.996	0.000
S06.00 Concussion (without open intracranial wound)	0.004	0.996	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.004	0.996	0.000
H52.3 Anisometropia and aniseikonia	0.004	0.996	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.004	0.996	0.000
Z50.0 Cardiac rehabilitation	0.000	0.996	0.004
H26.0 Infantile, juvenile and presenile cataract	0.004	0.996	0.000
M21.24 Flexion deformity (Hand)	0.004	0.996	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.004	0.996	0.000
H26 Other cataract	0.004	0.996	0.000
M45 Ankylosing spondylitis	0.004	0.996	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.003	0.997	0.000
H05.0 Acute inflammation of orbit	0.003	0.997	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M48 Other spondylopathies	0.003	0.997	0.000
K51.9 Ulcerative colitis, unspecified	0.003	0.997	0.000
M21.2 Flexion deformity	0.003	0.997	0.000
M21.23 Flexion deformity (Forearm)	0.003	0.997	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.003	0.997	0.000
H26.2 Complicated cataract	0.003	0.997	0.000
M47.2 Other spondylosis with radiculopathy	0.003	0.997	0.000
S32.51 Fracture of pubis (open)	0.000	0.997	0.003
M80.0 Postmenopausal osteoporosis with pathological fracture	0.003	0.997	0.000
M45-M49 Spondylopathies	0.003	0.997	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.003	0.997	0.000
L81.4 Other melanin hyperpigmentation	0.000	0.997	0.003
Z98.0 Intestinal bypass and anastomosis status	0.003	0.997	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.003	0.997	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.003	0.997	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.003	0.997	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.003	0.997	0.000
K04.5 Chronic apical periodontitis	0.000	0.997	0.003
M46 Other inflammatory spondylopathies	0.003	0.997	0.000
M48.9 Spondylopathy, unspecified	0.003	0.997	0.000
K04.6 Periapical abscess with sinus	0.000	0.997	0.003
M21.25 Flexion deformity (Pelvic region and thigh)	0.003	0.997	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.003	0.997	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.003	0.997	0.000
H26.3 Drug-induced cataract	0.003	0.997	0.000
M50.0 Cervical disk disorder with myelopathy	0.003	0.997	0.000
M48.8 Other specified spondylopathies	0.003	0.997	0.000
M46.44 Discitis, unspecified (Thoracic region)	0.003	0.997	0.000
M46.4 Discitis, unspecified	0.003	0.997	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.003	0.997	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.003	0.997	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.003	0.997	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.003	0.997	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.003	0.997	0.000
M21.26 Flexion deformity (Lower leg)	0.003	0.997	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.003	0.997	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.003	0.997	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.003	0.997	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.003	0.997	0.000
I78.1 Naevus, nonneoplastic	0.003	0.997	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.003	0.997	0.000
M47 Spondylosis	0.003	0.997	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.003	0.997	0.000
W02.9 Unspecified place	0.000	0.997	0.003
M46.2 Osteomyelitis of vertebra	0.003	0.997	0.000
M48.4 Fatigue fracture of vertebra	0.003	0.997	0.000
M48.3 Traumatic spondylopathy	0.003	0.997	0.000
M48.2 Kissing spine	0.003	0.997	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.003	0.997	0.000
K05.1 Chronic gingivitis	0.000	0.997	0.003
M21.29 Flexion deformity (Site unspecified)	0.002	0.997	0.000
M21.28 Flexion deformity (Other)	0.002	0.997	0.000
M21.22 Flexion deformity (Upper arm)	0.002	0.997	0.000
M21.21 Flexion deformity (Shoulder region)	0.002	0.997	0.000
M21.20 Flexion deformity (Multiple sites)	0.002	0.997	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.003	0.997	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.002	0.997	0.000
Z98.1 Arthrodesis status	0.003	0.997	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.003	0.997	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.002	0.997	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.002	0.997	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.002	0.997	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.002	0.997	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.002	0.997	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.002	0.997	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.002	0.997	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.002	0.997	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.002	0.997	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.002	0.997	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.997	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.002	0.997	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.002	0.997	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.002	0.997	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.002	0.997	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.002	0.997	0.000
E53 Deficiency of other B group vitamins	0.002	0.997	0.000
M47.1 Other spondylosis with myelopathy	0.002	0.997	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
M46.8 Other specified inflammatory spondylopathies	0.002	0.998	0.000
M46.5 Other infective spondylopathies	0.002	0.998	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.002	0.998	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.002	0.998	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.002	0.998	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.998	0.002
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.002	0.998	0.000
M46.0 Spinal enthesopathy	0.002	0.998	0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.002	0.998	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.002	0.998	0.000
M21.27 Flexion deformity (Ankle and foot)	0.002	0.998	0.000
M46.49 Discitis, unspecified (Site unspecified)	0.002	0.998	0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.47 Discitis, unspecified (Lumbosacral region)	0.002	0.998	0.000
M46.45 Discitis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M46.43 Discitis, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M46.42 Discitis, unspecified (Cervical region)	0.002	0.998	0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.002	0.998	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.002	0.998	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.002	0.998	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.002	0.998	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.002	0.998	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.002	0.998	0.000
M49 Spondylopathies in diseases classified elsewhere	0.002	0.998	0.000
K05.6 Periodontal disease, unspecified	0.000	0.998	0.002
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.002	0.998	0.000
H05.2 Exophthalmic conditions	0.002	0.998	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.002	0.998	0.000
H17.8 Other corneal scars and opacities	0.002	0.998	0.000
C67.2 Lateral wall of bladder	0.002	0.998	0.000
H26.8 Other specified cataract	0.002	0.998	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.002	0.998	0.000
H17 Corneal scars and opacities	0.002	0.998	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.002	0.998	0.000
H05 Disorders of orbit	0.002	0.998	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.002	0.998	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.002	0.998	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.002	0.998	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.002	0.998	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.002	0.998	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.002	0.998	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.002	0.998	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.002	0.998	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.002	0.998	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.002	0.998	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.002	0.998	0.000
M48.29 Kissing spine (Site unspecified)	0.002	0.998	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.27 Kissing spine (Lumbosacral region)	0.002	0.998	0.000
M48.26 Kissing spine (Lumbar region)	0.002	0.998	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.002	0.998	0.000
M48.24 Kissing spine (Thoracic region)	0.002	0.998	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.002	0.998	0.000
M48.22 Kissing spine (Cervical region)	0.002	0.998	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.002	0.998	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.002	0.998	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.002	0.998	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.002	0.998	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.002	0.998	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.002	0.998	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.002	0.998	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.002	0.998	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.002	0.998	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.002	0.998	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.002	0.998	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.002	0.998	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.002	0.998	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.002	0.998	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.002	0.998	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.002	0.998	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.002	0.998	0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.002	0.998	0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.002	0.998	0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.002	0.998	0.000
M46.22 Osteomyelitis of vertebra (Cervical region)	0.002	0.998	0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.002	0.998	0.000
H26.1 Traumatic cataract	0.002	0.998	0.000
H00 Hordeolum and chalazion	0.000	0.998	0.002
K05 Gingivitis and periodontal diseases	0.000	0.998	0.002
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.002	0.998	0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.002	0.998	0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.002	0.998	0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.002	0.998	0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.002	0.998	0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.002	0.998	0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.002	0.998	0.000
H15 Disorders of sclera	0.002	0.998	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.002	0.998	0.000
R27.0 Ataxia, unspecified	0.000	0.998	0.002
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.998	0.002
E53.1 Pyridoxine deficiency	0.002	0.998	0.000
E53.0 Riboflavin deficiency	0.002	0.998	0.000
H05.1 Chronic inflammatory disorders of orbit	0.002	0.998	0.000
K05.3 Chronic periodontitis	0.000	0.998	0.002
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.002	0.998	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.002	0.998	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.002	0.998	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.002	0.998	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.002	0.998	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
M46.59 Other infective spondylopathies (Site unspecified)	0.002	0.998	0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.57 Other infective spondylopathies (Lumbosacral region)	0.002	0.998	0.000
M46.56 Other infective spondylopathies (Lumbar region)	0.002	0.998	0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.002	0.998	0.000
M46.54 Other infective spondylopathies (Thoracic region)	0.002	0.998	0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.002	0.998	0.000
M46.52 Other infective spondylopathies (Cervical region)	0.002	0.998	0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.002	0.998	0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.002	0.998	0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)	0.002	0.998	0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)	0.002	0.998	0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)	0.002	0.998	0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)	0.002	0.998	0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)	0.002	0.998	0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)	0.002	0.998	0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)	0.002	0.998	0.000
C67.4 Posterior wall of bladder	0.002	0.998	0.000
H20 Iridocyclitis	0.002	0.998	0.000
E53.9 Vitamin B deficiency, unspecified	0.002	0.998	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.002	0.998	0.000
M46.09 Spinal enthesopathy (Site unspecified)	0.002	0.998	0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M46.07 Spinal enthesopathy (Lumbosacral region)	0.002	0.998	0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.002	0.998	0.000
M46.04 Spinal enthesopathy (Thoracic region)	0.002	0.998	0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.002	0.998	0.000
M46.02 Spinal enthesopathy (Cervical region)	0.002	0.998	0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.002	0.998	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
Z98 Other postsurgical states	0.002	0.998	0.000
L57.0 Actinic keratosis	0.000	0.998	0.002
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
H05.9 Disorder of orbit, unspecified	0.002	0.998	0.000
H15.1 Episcleritis	0.002	0.998	0.000
K05.5 Other periodontal diseases	0.000	0.998	0.002
M49.8 Spondylopathy in other diseases classified elsewhere	0.002	0.998	0.000
M49.4 Neuropathic spondylopathy	0.002	0.998	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
M49.2 Enterobacterial spondylitis	0.002	0.998	0.000
M49.1 Brucella spondylitis	0.002	0.998	0.000
M49.0 Tuberculosis of spine	0.002	0.998	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.002	0.998	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.002	0.998	0.000
R27.8 Other and unspecified lack of coordination	0.000	0.998	0.002
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.002	0.998	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.002	0.998	0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.002	0.998	0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.002	0.998	0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.002	0.998	0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.002	0.998	0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.002	0.998	0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.002	0.998	0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.002	0.998	0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.002	0.998	0.000
H05.4 Enophthalmos	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.002	0.998	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.002	0.998	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
H17.1 Other central corneal opacity	0.002	0.998	0.000
H17.0 Adherent leukoma	0.002	0.998	0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.5 Reovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.002	0.998	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.002	0.998	0.000
H05.3 Deformity of orbit	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.002	0.998	0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.002	0.998	0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.002	0.998	0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.002	0.998	0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.002	0.998	0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.002	0.998	0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.002	0.998	0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.002	0.998	0.000
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.002	0.998	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.002	0.998	0.000
H15.0 Scleritis	0.002	0.998	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.998	0.002
S32.30 Fracture of ilium (closed)	0.000	0.998	0.002
S32.3 Fracture of ilium	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations