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Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2456973
log Bayes Factor = 8.46648
Chromosome 12   position 56,416,928  (GRCh37) Explore rs2456973 on Ensembl!
Variant rs2456973 is listed in the   GWAS Catalog   ⇪
Variant rs2456973 is part of Cluster X0215

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J45.9 Asthma, unspecified
1.000 0.000 0.000
J33.9 Nasal polyp, unspecified
0.991 0.009 0.000
E10 Insulin-dependent diabetes mellitus
0.987 0.013 0.000
E10.9 Without complications
0.987 0.013 0.000
J33 Nasal polyp
0.986 0.014 0.000
J33.8 Other polyp of sinus
0.980 0.020 0.000
E10.3 With ophthalmic complications
0.965 0.035 0.000
J33.0 Polyp of nasal cavity
0.928 0.072 0.000
E10.1 With ketoacidosis
0.921 0.079 0.000
E10.5 With peripheral circulatory complications
0.911 0.089 0.000
E10.4 With neurological complications
0.868 0.132 0.000
E10.0 With coma
0.831 0.169 0.000
E10.6 With other specified complications
0.794 0.206 0.000
E10.2 With renal complications
0.783 0.217 0.000
E03.9 Hypothyroidism, unspecified
0.779 0.221 0.000
J33.1 Polypoid sinus degeneration
0.754 0.245 0.000
E10.8 With unspecified complications
0.706 0.294 0.000
E10.7 With multiple complications
0.678 0.322 0.000
E03 Other hypothyroidism
0.357 0.643 0.000
J45 Asthma
0.301 0.699 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.285 0.715 0.000
E03.5 Myxoedema coma
0.256 0.744 0.000
E03.4 Atrophy of thyroid (acquired)
0.256 0.744 0.000
E03.3 Postinfectious hypothyroidism
0.256 0.744 0.000
E03.1 Congenital hypothyroidism without goitre
0.252 0.748 0.000
E03.8 Other specified hypothyroidism
0.244 0.756 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.222 0.778 0.000
J45.1 Nonallergic asthma
0.217 0.782 0.000
J45.8 Mixed asthma
0.213 0.787 0.000
J45.0 Predominantly allergic asthma
0.153 0.847 0.000
E10-E14 Diabetes mellitus
0.145 0.855 0.000
E12 Malnutrition-related diabetes mellitus
0.104 0.896 0.000
E13 Other specified diabetes mellitus
0.099 0.901 0.000
E00-E07 Disorders of thyroid gland
0.083 0.917 0.000
E13.3 With ophthalmic complications
0.078 0.922 0.000
E12.9 Without complications
0.075 0.925 0.000
E12.8 With unspecified complications
0.075 0.925 0.000
E12.7 With multiple complications
0.075 0.925 0.000
E12.6 With other specified complications
0.075 0.925 0.000
E12.5 With peripheral circulatory complications
0.075 0.925 0.000
E12.4 With neurological complications
0.075 0.925 0.000
E12.3 With ophthalmic complications
0.075 0.925 0.000
E12.2 With renal complications
0.075 0.925 0.000
E12.1 With ketoacidosis
0.075 0.925 0.000
E12.0 With coma
0.075 0.925 0.000
E13.8 With unspecified complications
0.071 0.928 0.000
E13.7 With multiple complications
0.071 0.928 0.000
E13.6 With other specified complications
0.071 0.928 0.000
E13.5 With peripheral circulatory complications
0.071 0.928 0.000
E13.4 With neurological complications
0.071 0.928 0.000
E13.2 With renal complications
0.071 0.928 0.000
E13.1 With ketoacidosis
0.071 0.928 0.000
E13.0 With coma
0.071 0.928 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.068 0.932 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.068 0.932 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.060 0.940 0.000
E00 Congenital iodine-deficiency syndrome
0.060 0.940 0.000
E13.9 Without complications
0.057 0.943 0.000
E14 Unspecified diabetes mellitus
0.055 0.945 0.000
E40-E46 Malnutrition
0.052 0.948 0.000
E07 Other disorders of thyroid
0.051 0.949 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.043 0.957 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.043 0.957 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.043 0.957 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.043 0.957 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.043 0.957 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.043 0.957 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.043 0.957 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.043 0.957 0.000
E14.1 With ketoacidosis
0.042 0.957 0.000
E14.2 Withrenal complications
0.042 0.958 0.000
E14.6 With other specified complications
0.042 0.958 0.000
E14.7 With multiple complications
0.040 0.960 0.000
E14.0 With coma
0.040 0.960 0.000
E07.8 Other specified disorders of thyroid
0.040 0.960 0.000
E46 Unspecified protein-energy malnutrition
0.040 0.960 0.000
E14.8 With unspecified complications
0.038 0.961 0.000
E14.5 With peripheral circulatory complications
0.038 0.962 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.037 0.963 0.000
E45 Retarded development following protein-energy malnutrition
0.037 0.963 0.000
E43 Unspecified severe protein-energy malnutrition
0.037 0.963 0.000
E42 Marasmic kwashiorkor
0.037 0.963 0.000
E41 Nutritional marasmus
0.037 0.963 0.000
E40 Kwashiorkor
0.037 0.963 0.000
E07.1 Dyshormogenetic goitre
0.037 0.963 0.000
E07.0 Hypersecretion of calcitonin
0.037 0.963 0.000
E14.4 With neurological complications
0.036 0.964 0.000
E50-E64 Other nutritional deficiencies
0.035 0.964 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.035 0.965 0.000
E06 Thyroiditis
0.033 0.967 0.000
I65.2 Occlusion and stenosis of carotid artery
0.030 0.970 0.000
E14.9 Without complications
0.029 0.971 0.000
E56 Other vitamin deficiencies
0.028 0.972 0.000
E54 Ascorbic acid deficiency
0.028 0.972 0.000
E63 Other nutritional deficiencies
0.028 0.972 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.028 0.972 0.000
E44.1 Mild protein-energy malnutrition
0.027 0.973 0.000
E44.0 Moderate protein-energy malnutrition
0.027 0.973 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.974 0.026
E64 Sequelae of malnutrition and other nutritional deficiencies
0.026 0.974 0.000
E50 Vitamin A deficiency
0.026 0.974 0.000
E60 Dietary zinc deficiency
0.026 0.974 0.000
E59 Dietary selenium deficiency
0.026 0.974 0.000
E52 Niacin deficiency [pellagra]
0.026 0.974 0.000
E15 Nondiabetic hypoglycaemic coma
0.025 0.974 0.000
E51 Thiamine deficiency
0.025 0.975 0.000
E58 Dietary calcium deficiency
0.025 0.975 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.976 0.024
E06.4 Drug-induced thyroiditis
0.024 0.976 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.024 0.976 0.000
E06.1 Subacute thyroiditis
0.024 0.976 0.000
E06.0 Acute thyroiditis
0.024 0.976 0.000
E65-E68 Obesity and other hyperalimentation
0.023 0.976 0.000
E56.1 Deficiency of vitamin K
0.023 0.977 0.000
E07.9 Disorder of thyroid, unspecified
0.023 0.977 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.000 0.977 0.023
E63.9 Nutritional deficiency, unspecified
0.022 0.978 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.000 0.978 0.022
E05.8 Other thyrotoxicosis
0.022 0.978 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.022 0.978 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.022 0.978 0.000
E06.5 Other chronic thyroiditis
0.022 0.978 0.000
E53 Deficiency of other B group vitamins
0.021 0.979 0.000
E56.9 Vitamin deficiency, unspecified
0.020 0.979 0.000
E56.8 Deficiency of other vitamins
0.020 0.979 0.000
E56.0 Deficiency of vitamin E
0.020 0.979 0.000
E63.8 Other specified nutritional deficiencies
0.020 0.980 0.000
E63.1 Imbalance of constituents of food intake
0.020 0.980 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.020 0.980 0.000
E05.5 Thyroid crisis or storm
0.020 0.980 0.000
E05.4 Thyrotoxicosis factitia
0.020 0.980 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.020 0.980 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.000 0.980 0.020
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.019 0.981 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.019 0.981 0.000
E06.9 Thyroiditis, unspecified
0.019 0.981 0.000
J40-J47 Chronic lower respiratory diseases
0.019 0.981 0.000
E50.9 Vitamin A deficiency, unspecified
0.018 0.981 0.000
E50.8 Other manifestations of vitamin A deficiency
0.018 0.981 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.018 0.981 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.018 0.981 0.000
E50.5 Vitamin A deficiency with night blindness
0.018 0.981 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.018 0.981 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.018 0.981 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.018 0.981 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.018 0.981 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.018 0.981 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.018 0.981 0.000
E64.8 Sequelae of other nutritional deficiencies
0.018 0.981 0.000
E64.3 Sequelae of rickets
0.018 0.981 0.000
E64.2 Sequelae of vitamin C deficiency
0.018 0.981 0.000
E64.1 Sequelae of vitamin A deficiency
0.018 0.981 0.000
E64.0 Sequelae of protein-energy malnutrition
0.018 0.981 0.000
E51.9 Thiamine deficiency, unspecified
0.018 0.982 0.000
E51.8 Other manifestations of thiamine deficiency
0.018 0.982 0.000
E51.1 Beriberi
0.018 0.982 0.000
E61 Deficiency of other nutrient elements
0.018 0.982 0.000
J43 Emphysema
0.018 0.982 0.000
E51.2 Wernicke's encephalopathy
0.018 0.982 0.000
E14.3 With ophthalmic complications
0.018 0.982 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.000 0.982 0.018
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.000 0.982 0.018
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.000 0.982 0.018
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.000 0.982 0.018
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.000 0.982 0.018
J43.9 Emphysema, unspecified
0.018 0.982 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.000 0.982 0.017
I65.1 Occlusion and stenosis of basilar artery
0.017 0.983 0.000
E67 Other hyperalimentation
0.017 0.983 0.000
E68 Sequelae of hyperalimentation
0.017 0.983 0.000
E55 Vitamin D deficiency
0.017 0.983 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.016 0.984 0.000
E53.1 Pyridoxine deficiency
0.015 0.984 0.000
E53.0 Riboflavin deficiency
0.015 0.984 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.015 0.985 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.015 0.985 0.000
E06.3 Autoimmune thyroiditis
0.014 0.985 0.000
J47 Bronchiectasis
0.014 0.986 0.000
E53.8 Deficiency of other specified B group vitamins
0.014 0.986 0.000
E65 Localised adiposity
0.013 0.986 0.000
J43.8 Other emphysema
0.014 0.986 0.000
I60 Subarachnoid haemorrhage
0.013 0.986 0.000
J41 Simple and mucopurulent chronic bronchitis
0.013 0.987 0.000
E53.9 Vitamin B deficiency, unspecified
0.013 0.987 0.000
E61.9 Deficiency of nutrient element, unspecified
0.013 0.987 0.000
E61.8 Deficiency of other specified nutrient elements
0.013 0.987 0.000
E61.7 Deficiency of multiple nutrient elements
0.013 0.987 0.000
E61.6 Vanadium deficiency
0.013 0.987 0.000
E61.5 Molybdenum deficiency
0.013 0.987 0.000
E61.4 Chromium deficiency
0.013 0.987 0.000
E61.3 Manganese deficiency
0.013 0.987 0.000
E61.0 Copper deficiency
0.013 0.987 0.000
I69.3 Sequelae of cerebral infarction
0.013 0.987 0.000
J43.1 Panlobular emphysema
0.013 0.987 0.000
J43.0 MacLeod's syndrome
0.013 0.987 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.013 0.987 0.000
E04 Other non-toxic goitre
0.012 0.987 0.001
I69 Sequelae of cerebrovascular disease
0.013 0.987 0.000
E67.8 Other specified hyperalimentation
0.012 0.987 0.000
E67.3 Hypervitaminosis D
0.012 0.987 0.000
E67.2 Megavitamin-B6 syndrome
0.012 0.987 0.000
E67.1 Hypercarotenaemia
0.012 0.987 0.000
E67.0 Hypervitaminosis A
0.012 0.987 0.000
E55.0 Rickets, active
0.012 0.988 0.000
J43.2 Centrilobular emphysema
0.012 0.988 0.000
I60.8 Other subarachnoid haemorrhage
0.012 0.988 0.000
E16 Other disorders of pancreatic internal secretion
0.012 0.988 0.000
I60-I69 Cerebrovascular diseases
0.012 0.988 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.012 0.988 0.000
R44.1 Visual hallucinations
0.012 0.988 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.011 0.988 0.000
E61.2 Magnesium deficiency
0.011 0.989 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.011 0.989 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.011 0.989 0.000
E11 Non-insulin-dependent diabetes mellitus
0.011 0.989 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.011 0.989 0.000
F31 Bipolar affective disorder
0.011 0.989 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.011 0.989 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.010 0.990 0.000
E04.0 Non-toxic diffuse goitre
0.010 0.990 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.010 0.990 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.010 0.990 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.010 0.990 0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.010 0.990 0.000
J41.1 Mucopurulent chronic bronchitis
0.010 0.990 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.010 0.990 0.000
I62 Other nontraumatic intracranial haemorrhage
0.010 0.990 0.000
E04.8 Other specified non-toxic goitre
0.009 0.990 0.001
J41.0 Simple chronic bronchitis
0.009 0.991 0.000
E11.7 With multiple complications
0.009 0.991 0.000
E11.0 With coma
0.009 0.991 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.009 0.991 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.009 0.991 0.000
E11.8 With unspecified complications
0.009 0.991 0.000
E61.1 Iron deficiency
0.009 0.991 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.009 0.991 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.009 0.991 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.009 0.991 0.000
E16.4 Abnormal secretion of gastrin
0.009 0.991 0.000
E16.3 Increased secretion of glucagon
0.009 0.991 0.000
J46 Status asthmaticus
0.009 0.991 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.009 0.991 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.009 0.991 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.008 0.992 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.008 0.992 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.008 0.992 0.000
E16.1 Other hypoglycaemia
0.008 0.992 0.000
F31.8 Other bipolar affective disorders
0.008 0.992 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.008 0.992 0.000
I63.9 Cerebral infarction, unspecified
0.008 0.992 0.000
C09.9 Tonsil, unspecified
0.000 0.992 0.008
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.008 0.992 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.008 0.992 0.000
R44.0 Auditory hallucinations
0.008 0.992 0.000
R59.1 Generalised enlarged lymph nodes
0.000 0.992 0.008
E05.0 Thyrotoxicosis with diffuse goitre
0.008 0.992 0.000
R44.3 Hallucinations, unspecified
0.008 0.992 0.000
F31.7 Bipolar affective disorder, currently in remission
0.007 0.993 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.007 0.993 0.000
E11.1 With ketoacidosis
0.007 0.993 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.007 0.993 0.000
E11.2 With renal complications
0.007 0.993 0.000
I62.1 Nontraumatic extradural haemorrhage
0.007 0.993 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.006 0.993 0.000
R80 Isolated proteinuria
0.000 0.993 0.007
R44.2 Other hallucinations
0.006 0.993 0.000
E11.6 With other specified complications
0.006 0.994 0.000
M17.0 Primary gonarthrosis, bilateral
0.000 0.994 0.006
J42 Unspecified chronic bronchitis
0.006 0.994 0.000
F31.9 Bipolar affective disorder, unspecified
0.006 0.994 0.000
H43.1 Vitreous haemorrhage
0.006 0.994 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.006 0.994 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.006 0.994 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.006 0.994 0.000
I63 Cerebral infarction
0.006 0.994 0.000
D47.1 Chronic myeloproliferative disease
0.000 0.994 0.006
E04.9 Non-toxic goitre, unspecified
0.000 0.994 0.005
E11.5 With peripheral circulatory complications
0.006 0.994 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.006 0.994 0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions
0.006 0.994 0.000
E20-E35 Disorders of other endocrine glands
0.006 0.994 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.005 0.994 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.005 0.994 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.005 0.994 0.000
I66.1 Occlusion and stenosis of anterior cerebral artery
0.005 0.994 0.000
C09 Malignant neoplasm of tonsil
0.000 0.995 0.005
E04.2 Non-toxic multinodular goitre
0.005 0.995 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.005 0.995 0.000
J40 Bronchitis, not specified as acute or chronic
0.005 0.995 0.000
I61 Intracerebral haemorrhage
0.005 0.995 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.005 0.995 0.000
I68.0 Cerebral amyloid angiopathy
0.005 0.995 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.000 0.995 0.005
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.005 0.995 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.005 0.995 0.000
E31 Polyglandular dysfunction
0.005 0.995 0.000
C01 Malignant neoplasm of base of tongue
0.000 0.995 0.005
I61.9 Intracerebral haemorrhage, unspecified
0.005 0.995 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.000 0.995 0.005
E11.3 With ophthalmic complications
0.005 0.995 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.995 0.005
C45.0 Mesothelioma of pleura
0.005 0.995 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.004 0.995 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.004 0.995 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.004 0.996 0.000
E20 Hypoparathyroidism
0.004 0.996 0.000
E27.1 Primary adrenocortical insufficiency
0.004 0.996 0.000
E27 Other disorders of adrenal gland
0.004 0.996 0.000
M46 Other inflammatory spondylopathies
0.000 0.996 0.004
E35 Disorders of endocrine glands in diseases classified elsewhere
0.004 0.996 0.000
E32 Diseases of thymus
0.004 0.996 0.000
E30 Disorders of puberty, not elsewhere classified
0.004 0.996 0.000
E26 Hyperaldosteronism
0.004 0.996 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.004 0.996 0.000
G40 Epilepsy
0.004 0.996 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.004 0.996 0.000
E31.0 Autoimmune polyglandular failure
0.004 0.996 0.000
E25 Adrenogenital disorders
0.004 0.996 0.000
E27.2 Addisonian crisis
0.004 0.996 0.000
C09.8 Overlapping lesion of tonsil
0.000 0.996 0.004
C09.1 Tonsillar pillar (anterior) (posterior)
0.000 0.996 0.004
C09.0 Tonsillar fossa
0.000 0.996 0.004
I61.8 Other intracerebral haemorrhage
0.004 0.996 0.000
E28 Ovarian dysfunction
0.004 0.996 0.000
Z83.5 Family history of eye and ear disorders
0.004 0.996 0.000
E24 Cushing's syndrome
0.004 0.996 0.000
G40.8 Other epilepsy
0.004 0.996 0.000
D47.4 Osteomyelofibrosis
0.000 0.996 0.004
C45 Mesothelioma
0.004 0.996 0.000
A04.8 Other specified bacterial intestinal infections
0.000 0.996 0.004
I61.3 Intracerebral haemorrhage in brain stem
0.004 0.996 0.000
E31.9 Polyglandular dysfunction, unspecified
0.004 0.996 0.000
E31.8 Other polyglandular dysfunction
0.004 0.996 0.000
E31.1 Polyglandular hyperfunction
0.004 0.996 0.000
K62.7 Radiation proctitis
0.000 0.996 0.004
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.004 0.996 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.996 0.004
C45.9 Mesothelioma, unspecified
0.004 0.996 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.003 0.996 0.000
E20.9 Hypoparathyroidism, unspecified
0.003 0.996 0.000
E55.9 Vitamin D deficiency, unspecified
0.003 0.996 0.000
K74.5 Biliary cirrhosis, unspecified
0.000 0.997 0.003
E20.8 Other hypoparathyroidism
0.003 0.997 0.000
E20.1 Pseudohypoparathyroidism
0.003 0.997 0.000
E20.0 Idiopathic hypoparathyroidism
0.003 0.997 0.000
Z11.2 Special screening examination for other bacterial diseases
0.000 0.997 0.003
E27.4 Other and unspecified adrenocortical insufficiency
0.003 0.997 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.997 0.003
M46.8 Other specified inflammatory spondylopathies
0.000 0.997 0.003
M46.5 Other infective spondylopathies
0.000 0.997 0.003
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.997 0.003
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.997 0.003
E27.5 Adrenomedullary hyperfunction
0.003 0.997 0.000
E27.0 Other adrenocortical overactivity
0.003 0.997 0.000
E26.9 Hyperaldosteronism, unspecified
0.003 0.997 0.000
E26.8 Other hyperaldosteronism
0.003 0.997 0.000
E26.1 Secondary hyperaldosteronism
0.003 0.997 0.000
E30.9 Disorder of puberty, unspecified
0.003 0.997 0.000
E30.8 Other disorders of puberty
0.003 0.997 0.000
E30.1 Precocious puberty
0.003 0.997 0.000
E30.0 Delayed puberty
0.003 0.997 0.000
E32.9 Disease of thymus, unspecified
0.003 0.997 0.000
E32.8 Other diseases of thymus
0.003 0.997 0.000
E32.1 Abscess of thymus
0.003 0.997 0.000
E32.0 Persistent hyperplasia of thymus
0.003 0.997 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.003 0.997 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.003 0.997 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.003 0.997 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.003 0.997 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.003 0.997 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.003 0.997 0.000
J30-J39 Other diseases of upper respiratory tract
0.003 0.997 0.000
E26.0 Primary hyperaldosteronism
0.003 0.997 0.000
E28.3 Primary ovarian failure
0.003 0.997 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.000 0.997 0.003
H47.3 Other disorders of optic disk
0.003 0.997 0.000
E04.1 Non-toxic single thyroid nodule
0.003 0.997 0.000
E25.9 Adrenogenital disorder, unspecified
0.003 0.997 0.000
E25.8 Other adrenogenital disorders
0.003 0.997 0.000
E29 Testicular dysfunction
0.003 0.997 0.000
J32.9 Chronic sinusitis, unspecified
0.003 0.997 0.000
C45.7 Mesothelioma of other sites
0.003 0.997 0.000
M46.0 Spinal enthesopathy
0.000 0.997 0.003
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.003 0.997 0.000
E28.9 Ovarian dysfunction, unspecified
0.003 0.997 0.000
E28.8 Other ovarian dysfunction
0.003 0.997 0.000
E28.1 Androgen excess
0.003 0.997 0.000
E28.0 Oestrogen excess
0.003 0.997 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.000 0.997 0.003
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.003 0.997 0.000
M46.2 Osteomyelitis of vertebra
0.000 0.997 0.003
E24.8 Other Cushing's syndrome
0.003 0.997 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.003 0.997 0.000
E24.3 Ectopic ACTH syndrome
0.003 0.997 0.000
E24.2 Drug-induced Cushing's syndrome
0.003 0.997 0.000
E24.1 Nelson's syndrome
0.003 0.997 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.000 0.997 0.003
C10 Malignant neoplasm of oropharynx
0.000 0.997 0.003
E24.9 Cushing's syndrome, unspecified
0.003 0.997 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.003 0.997 0.000
E05.9 Thyrotoxicosis, unspecified
0.003 0.997 0.000
H47.1 Papilloedema, unspecified
0.003 0.997 0.000
R40.0 Somnolence
0.000 0.997 0.003
C04.9 Floor of mouth, unspecified
0.000 0.997 0.003
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.003 0.997 0.000
H52.1 Myopia
0.003 0.997 0.000
C04 Malignant neoplasm of floor of mouth
0.000 0.997 0.003
E23 Hypofunction and other disorders of pituitary gland
0.003 0.997 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.003 0.997 0.000
C45.2 Mesothelioma of pericardium
0.003 0.997 0.000
C45.1 Mesothelioma of peritoneum
0.003 0.997 0.000
G40.9 Epilepsy, unspecified
0.003 0.997 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.003 0.997 0.000
H25.0 Senile incipient cataract
0.003 0.997 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.003 0.997 0.000
C10.9 Oropharynx, unspecified
0.000 0.997 0.003
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.003 0.997 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.003 0.997 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.997 0.003
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.997 0.003
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.997 0.003
I77.6 Arteritis, unspecified
0.000 0.997 0.003
C03 Malignant neoplasm of gum
0.000 0.997 0.003
E34 Other endocrine disorders
0.003 0.997 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.003 0.997 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.003 0.997 0.000
G51.9 Disorder of facial nerve, unspecified
0.003 0.997 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.003 0.997 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.997 0.003
J37 Chronic laryngitis and laryngotracheitis
0.003 0.997 0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)
0.000 0.997 0.003
E24.0 Pituitary-dependent Cushing's disease
0.003 0.997 0.000
M95.4 Acquired deformity of chest and rib
0.000 0.997 0.003
M46.59 Other infective spondylopathies (Site unspecified)
0.000 0.997 0.002
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.000 0.997 0.002
M46.57 Other infective spondylopathies (Lumbosacral region)
0.000 0.997 0.002
M46.56 Other infective spondylopathies (Lumbar region)
0.000 0.997 0.002
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.000 0.997 0.002
M46.54 Other infective spondylopathies (Thoracic region)
0.000 0.997 0.002
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.000 0.997 0.002
M46.52 Other infective spondylopathies (Cervical region)
0.000 0.997 0.002
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.000 0.997 0.002
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.000 0.997 0.002
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.000 0.997 0.002
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.000 0.997 0.002
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.000 0.997 0.002
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.000 0.997 0.002
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.000 0.997 0.002
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.000 0.997 0.002
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)
0.000 0.997 0.002
M46.82 Other specified inflammatory spondylopathies (Cervical region)
0.000 0.997 0.002
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)
0.000 0.997 0.002
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)
0.000 0.997 0.002
C80.9 Malignant neoplasm, unspecified
0.000 0.997 0.003
J32 Chronic sinusitis
0.003 0.997 0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)
0.000 0.997 0.002
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)
0.000 0.997 0.002
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)
0.000 0.997 0.002
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)
0.000 0.997 0.002
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)
0.000 0.997 0.002
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)
0.000 0.997 0.002
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)
0.000 0.997 0.002
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)
0.000 0.997 0.002
C02.9 Tongue, unspecified
0.000 0.997 0.003
E28.2 Polycystic ovarian syndrome
0.003 0.997 0.000
M95.0 Acquired deformity of nose
0.000 0.997 0.003
E66 Obesity
0.002 0.997 0.000
E29.9 Testicular dysfunction, unspecified
0.002 0.997 0.000
E29.8 Other testicular dysfunction
0.002 0.997 0.000
E29.0 Testicular hyperfunction
0.002 0.997 0.000
C02.4 Lingual tonsil
0.000 0.997 0.002
M46.09 Spinal enthesopathy (Site unspecified)
0.000 0.997 0.002
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.000 0.997 0.002
M46.07 Spinal enthesopathy (Lumbosacral region)
0.000 0.997 0.002
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.000 0.997 0.002
M46.04 Spinal enthesopathy (Thoracic region)
0.000 0.997 0.002
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.000 0.997 0.002
M46.02 Spinal enthesopathy (Cervical region)
0.000 0.997 0.002
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.000 0.997 0.002
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.000 0.997 0.002
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.997 0.003
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.000 0.997 0.002
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.000 0.997 0.002
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.000 0.997 0.002
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.000 0.997 0.002
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.000 0.997 0.002
M46.22 Osteomyelitis of vertebra (Cervical region)
0.000 0.997 0.002
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.000 0.997 0.002
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.000 0.997 0.002
C05 Malignant neoplasm of palate
0.000 0.997 0.002
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.000 0.997 0.002
C11 Malignant neoplasm of nasopharynx
0.000 0.997 0.002
C07 Malignant neoplasm of parotid gland
0.000 0.997 0.002
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)
0.000 0.997 0.002
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.997 0.003
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.000 0.997 0.002
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.000 0.997 0.002
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.000 0.997 0.002
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.000 0.997 0.002
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.000 0.997 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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