TreeWAS – Variant ID: rs2459210

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K74.6 Other and unspecified cirrhosis of liver	0.406	0.594	0.000
K74 Fibrosis and cirrhosis of liver	0.388	0.612	0.000
K74.0 Hepatic fibrosis	0.355	0.645	0.000
K70-K77 Diseases of liver	0.342	0.658	0.000
K72 Hepatic failure, not elsewhere classified	0.336	0.664	0.000
K72.9 Hepatic failure, unspecified	0.333	0.667	0.000
K73 Chronic hepatitis, not elsewhere classified	0.296	0.704	0.000
K75 Other inflammatory liver diseases	0.295	0.705	0.000
K75.8 Other specified inflammatory liver diseases	0.287	0.713	0.000
K74.1 Hepatic sclerosis	0.285	0.715	0.000
K74.5 Biliary cirrhosis, unspecified	0.282	0.718	0.000
K74.4 Secondary biliary cirrhosis	0.278	0.722	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.278	0.722	0.000
K74.3 Primary biliary cirrhosis	0.266	0.734	0.000
K73.9 Chronic hepatitis, unspecified	0.261	0.739	0.000
K72.1 Chronic hepatic failure	0.255	0.745	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.244	0.756	0.000
K77 Liver disorders in diseases classified elsewhere	0.241	0.759	0.000
K76 Other diseases of liver	0.236	0.764	0.000
K72.0 Acute and subacute hepatic failure	0.231	0.769	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.230	0.770	0.000
K76.6 Portal hypertension	0.224	0.776	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.213	0.787	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.213	0.787	0.000
K75.2 Nonspecific reactive hepatitis	0.211	0.788	0.000
K75.1 Phlebitis of portal vein	0.211	0.788	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.199	0.801	0.000
K76.8 Other specified diseases of liver	0.193	0.807	0.000
K75.4 Autoimmune hepatitis	0.183	0.817	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.173	0.827	0.000
K76.5 Hepatic veno-occlusive disease	0.170	0.830	0.000
K76.4 Peliosis hepatis	0.170	0.830	0.000
K76.2 Central haemorrhagic necrosis of liver	0.170	0.830	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.168	0.832	0.000
K71 Toxic liver disease	0.166	0.833	0.000
K76.3 Infarction of liver	0.165	0.834	0.000
K76.1 Chronic passive congestion of liver	0.163	0.837	0.000
K76.7 Hepatorenal syndrome	0.156	0.844	0.000
K71.0 Toxic liver disease with cholestasis	0.120	0.879	0.000
K71.8 Toxic liver disease with other disorders of liver	0.119	0.880	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.119	0.880	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.119	0.880	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.119	0.880	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.119	0.880	0.000
K71.2 Toxic liver disease with acute hepatitis	0.119	0.880	0.000
K75.9 Inflammatory liver disease, unspecified	0.118	0.882	0.000
K75.0 Abscess of liver	0.106	0.894	0.000
K71.9 Toxic liver disease, unspecified	0.104	0.895	0.001
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.100	0.899	0.001
K71.1 Toxic liver disease with hepatic necrosis	0.098	0.902	0.001
K70 Alcoholic liver disease	0.090	0.910	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.090	0.910	0.000
K70.3 Alcoholic cirrhosis of liver	0.066	0.933	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.056	0.944	0.000
K70.1 Alcoholic hepatitis	0.055	0.945	0.000
K70.0 Alcoholic fatty liver	0.051	0.949	0.000
K70.9 Alcoholic liver disease, unspecified	0.050	0.950	0.000
K70.4 Alcoholic hepatic failure	0.047	0.952	0.000
K76.9 Liver disease, unspecified	0.044	0.956	0.000
D04.7 Skin of lower limb, including hip	0.026	0.974	0.000
D04 Carcinoma in situ of skin	0.025	0.975	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.024	0.976	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.024	0.976	0.000
D04.3 Skin of other and unspecified parts of face	0.023	0.977	0.000
D04.5 Skin of trunk	0.022	0.978	0.000
D04.2 Skin of ear and external auricular canal	0.022	0.978	0.000
D22 Melanocytic naevi	0.022	0.978	0.000
D04.6 Skin of upper limb, including shoulder	0.021	0.979	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.021	0.979	0.000
D04.0 Skin of lip	0.020	0.980	0.000
D04.4 Skin of scalp and neck	0.020	0.980	0.000
D22.4 Melanocytic naevi of scalp and neck	0.018	0.982	0.000
D04.8 Skin of other sites	0.018	0.982	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.982	0.018
D04.1 Skin of eyelid, including canthus	0.017	0.983	0.000
D22.0 Melanocytic naevi of lip	0.016	0.984	0.000
D04.9 Skin, unspecified	0.016	0.984	0.000
H81.1 Benign paroxysmal vertigo	0.016	0.984	0.000
D22.9 Melanocytic naevi, unspecified	0.015	0.985	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.014	0.986	0.000
H81 Disorders of vestibular function	0.014	0.986	0.000
H81.0 Meniere's disease	0.013	0.987	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.013	0.987	0.000
H81.2 Vestibular neuronitis	0.012	0.988	0.000
H81.3 Other peripheral vertigo	0.011	0.989	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.989	0.011
H81.4 Vertigo of central origin	0.010	0.989	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.990	0.010
H81.8 Other disorders of vestibular function	0.009	0.991	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.991	0.009
E89.4 Postprocedural ovarian failure	0.000	0.991	0.009
E89.5 Postprocedural testicular hypofunction	0.000	0.991	0.009
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.991	0.008
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.992	0.008
T42.4 Benzodiazepines	0.008	0.992	0.000
H81.9 Disorder of vestibular function, unspecified	0.008	0.992	0.000
E89.1 Postprocedural hypoinsulinaemia	0.000	0.992	0.008
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.992	0.008
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.008	0.992	0.000
D23.6 Skin of upper limb, including shoulder	0.007	0.993	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.007	0.993	0.000
D22.5 Melanocytic naevi of trunk	0.007	0.993	0.000
B34.9 Viral infection, unspecified	0.007	0.993	0.000
T42.3 Barbiturates	0.006	0.994	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.006	0.994	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.006	0.994	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.006	0.994	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.994	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.006	0.994	0.000
T42.0 Hydantoin derivatives	0.006	0.994	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.006	0.994	0.000
T36 Poisoning by systemic antibiotics	0.006	0.994	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.006	0.994	0.000
T42.2 Succinimides and oxazolidinediones	0.006	0.994	0.000
T39.1 4-Aminophenol derivatives	0.006	0.994	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
T42.1 Iminostilbenes	0.005	0.995	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.005	0.995	0.000
T39.0 Salicylates	0.005	0.995	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.005	0.995	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
I98.0 Cardiovascular syphilis	0.005	0.995	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
T46.1 Calcium-channel blockers	0.005	0.995	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.005	0.995	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.005	0.995	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.995	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
T36.3 Macrolides	0.005	0.995	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.005	0.995	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.005	0.995	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.005	0.995	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.005	0.995	0.000
B34 Viral infection of unspecified site	0.005	0.995	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.995	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.005	0.995	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.004	0.995	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.005	0.995	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.004	0.995	0.000
T36.4 Tetracyclines	0.004	0.996	0.000
T36.8 Other systemic antibiotics	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.996	0.000
T50.5 Appetite depressants	0.004	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.996	0.000
L53.9 Erythematous condition, unspecified	0.004	0.996	0.000
T50.8 Diagnostic agents	0.004	0.996	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.000	0.996	0.004
T47.4 Other laxatives	0.004	0.996	0.000
T36.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
T36.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
T36.6 Rifamycins	0.004	0.996	0.000
T36.5 Aminoglycosides	0.004	0.996	0.000
T36.2 Chloramphenicol group	0.004	0.996	0.000
T36.0 Penicillins	0.004	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.004	0.996	0.000
T39.2 Pyrazolone derivatives	0.004	0.996	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.004	0.996	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.004	0.996	0.000
T38.0 Glucocorticoids and synthetic analogues	0.004	0.996	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.004	0.996	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
T48.4 Expectorants	0.004	0.996	0.000
T48.3 Antitussives	0.004	0.996	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
T48.0 Oxytocic drugs	0.004	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
T47.7 Emetics	0.004	0.996	0.000
T47.5 Digestants	0.004	0.996	0.000
T47.3 Saline and osmotic laxatives	0.004	0.996	0.000
T38.5 Other oestrogens and progestogens	0.004	0.996	0.000
T47.6 Antidiarrhoeal drugs	0.004	0.996	0.000
T49.9 Topical agent, unspecified	0.004	0.996	0.000
T49.8 Other topical agents	0.004	0.996	0.000
T49.7 Dental drugs, topically applied	0.004	0.996	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.004	0.996	0.000
T49.5 Ophthalmological drugs and preparations	0.004	0.996	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.004	0.996	0.000
T49.3 Emollients, demulcents and protectants	0.004	0.996	0.000
T49.2 Local astringents and local detergents	0.004	0.996	0.000
T49.1 Antipruritics	0.004	0.996	0.000
M25.84 Other specified joint disorders (Hand)	0.000	0.996	0.004
T48.5 Anti-common-cold drugs	0.004	0.996	0.000
T43.2 Other and unspecified antidepressants	0.004	0.996	0.000
Z91.5 Personal history of self-harm	0.004	0.996	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.996	0.004
T38.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
T38.7 Androgens and anabolic congeners	0.004	0.996	0.000
T38.4 Oral contraceptives	0.004	0.996	0.000
T38.2 Antithyroid drugs	0.004	0.996	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.004	0.996	0.000
T47.0 Histamine H(2)-receptor antagonists	0.004	0.996	0.000
B34.4 Papovirus infection, unspecified	0.004	0.996	0.000
H66.9 Otitis media, unspecified	0.000	0.996	0.004
T41.5 Therapeutic gases	0.004	0.996	0.000
T41.4 Anaesthetic, unspecified	0.004	0.996	0.000
T41.3 Local anaesthetics	0.004	0.996	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
T41.1 Intravenous anaesthetics	0.004	0.996	0.000
T41.0 Inhaled anaesthetics	0.004	0.996	0.000
T47.2 Stimulant laxatives	0.004	0.996	0.000
B34.8 Other viral infections of unspecified site	0.004	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.004	0.996	0.000
B34.1 Enterovirus infection, unspecified	0.003	0.996	0.000
H18.4 Corneal degeneration	0.000	0.996	0.004
M94.8 Other specified disorders of cartilage	0.000	0.996	0.004
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.996	0.004
B34.2 Coronavirus infection, unspecified	0.003	0.996	0.000
B34.0 Adenovirus infection, unspecified	0.003	0.996	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.996	0.000
B34.3 Parvovirus infection, unspecified	0.003	0.996	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
T45.4 Iron and its compounds	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.997	0.003
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.997	0.000
L53.8 Other specified erythematous conditions	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.000	0.997	0.003
N28.1 Cyst of kidney, acquired	0.003	0.997	0.000
L53 Other erythematous conditions	0.003	0.997	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
M94.88 Other specified disorders of cartilage (Other)	0.000	0.997	0.003
T45.2 Vitamins, not elsewhere classified	0.003	0.997	0.000
Z22.5 Carrier of viral hepatitis	0.003	0.997	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.997	0.003
M94.81 Other specified disorders of cartilage (Shoulder region)	0.000	0.997	0.003
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.997	0.003
M25.8 Other specified joint disorders	0.000	0.997	0.003
M94.84 Other specified disorders of cartilage (Hand)	0.000	0.997	0.003
M94.83 Other specified disorders of cartilage (Forearm)	0.000	0.997	0.003
M94.82 Other specified disorders of cartilage (Upper arm)	0.000	0.997	0.003
M94.80 Other specified disorders of cartilage (Multiple sites)	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.997	0.003
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
T44.0 Anticholinesterase agents	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.997	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.997	0.000
T86.1 Kidney transplant failure and rejection	0.000	0.997	0.003
L53.3 Other chronic figurate erythema	0.002	0.997	0.000
L53.2 Erythema marginatum	0.002	0.997	0.000
L53.1 Erythema annulare centrifugum	0.002	0.997	0.000
L53.0 Toxic erythema	0.002	0.997	0.000
M25.88 Other specified joint disorders (Other)	0.000	0.998	0.002
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.000	0.998	0.002
M25.82 Other specified joint disorders (Upper arm)	0.000	0.998	0.002
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.998	0.002
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.998	0.002
J03.9 Acute tonsillitis, unspecified	0.002	0.998	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.998	0.002
B25-B34 Other viral diseases	0.002	0.998	0.000
I99 Other and unspecified disorders of circulatory system	0.002	0.998	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.998	0.002
I95-I99 Other and unspecified disorders of the circulatory system	0.002	0.998	0.000
K55.2 Angiodysplasia of colon	0.002	0.998	0.000
M25.83 Other specified joint disorders (Forearm)	0.000	0.998	0.002
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
T40.5 Cocaine	0.002	0.998	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
Z51.3 Blood transfusion without reported diagnosis	0.002	0.998	0.000
H80-H83 Diseases of inner ear	0.002	0.998	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.998	0.002
T40.1 Heroin	0.002	0.998	0.000
B27 Infectious mononucleosis	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
K61.3 Ischiorectal abscess	0.002	0.998	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.998	0.002
D76.3 Other histiocytosis syndromes	0.000	0.998	0.002
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.998	0.002
D09.0 Bladder	0.002	0.998	0.000
K60.1 Chronic anal fissure	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
B30 Viral conjunctivitis	0.002	0.998	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
B27.9 Infectious mononucleosis, unspecified	0.002	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.998	0.002
M60.05 Infective myositis (Pelvic region and thigh)	0.002	0.998	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.002	0.998	0.000
O63.1 Prolonged second stage (of labour)	0.002	0.998	0.000
L85.9 Epidermal thickening, unspecified	0.000	0.998	0.002
B26 Mumps	0.002	0.998	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.002	0.998	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.998	0.002
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.002	0.998	0.000
B25 Cytomegaloviral disease	0.002	0.998	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.998	0.002
B33 Other viral diseases, not elsewhere classified	0.002	0.998	0.000
M25.86 Other specified joint disorders (Lower leg)	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
B27.8 Other infectious mononucleosis	0.002	0.998	0.000
B27.1 Cytomegaloviral mononucleosis	0.002	0.998	0.000
B30.9 Viral conjunctivitis, unspecified	0.002	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.000	0.998	0.002
C48.2 Peritoneum, unspecified	0.002	0.998	0.000
D09 Carcinoma in situ of other and unspecified sites	0.002	0.998	0.000
B27.0 Gammaherpesviral mononucleosis	0.002	0.998	0.000
B30.8 Other viral conjunctivitis	0.001	0.998	0.000
B30.3 Acute epidemic haemorrhagic conjunctivitis (enteroviral)	0.001	0.998	0.000
B30.2 Viral pharyngoconjunctivitis	0.001	0.998	0.000
B30.1 Conjunctivitis due to adenovirus	0.001	0.998	0.000
B30.0 Keratoconjunctivitis due to adenovirus	0.001	0.998	0.000
D09.9 Carcinoma in situ, unspecified	0.002	0.998	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.000	0.998	0.002
M60.08 Infective myositis (Other)	0.002	0.998	0.000
D21.3 Connective and other soft tissue of thorax	0.002	0.998	0.000
B26.9 Mumps without complication	0.001	0.998	0.000
B26.8 Mumps with other complications	0.001	0.998	0.000
B26.3 Mumps pancreatitis	0.001	0.998	0.000
B26.2 Mumps encephalitis	0.001	0.998	0.000
B26.1 Mumps meningitis	0.001	0.998	0.000
B26.0 Mumps orchitis	0.001	0.998	0.000
D21.5 Connective and other soft tissue of pelvis	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.000	0.998	0.002
M23.30 Other meniscus derangements (Multiple sites)	0.002	0.998	0.000
B25.9 Cytomegaloviral disease, unspecified	0.002	0.998	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.002	0.998	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.998	0.002
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.998	0.002
M60.0 Infective myositis	0.002	0.998	0.000
B25.2 Cytomegaloviral pancreatitis	0.001	0.998	0.000
B25.1 Cytomegaloviral hepatitis	0.001	0.998	0.000
B33.8 Other specified viral diseases	0.001	0.998	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
B33.0 Epidemic myalgia	0.001	0.998	0.000
O62.1 Secondary uterine inertia	0.000	0.998	0.002
B33.4 Hantavirus (cardio-)pulmonary syndrome [HPS] [HCPS]	0.001	0.998	0.000
B33.3 Retrovirus infections, not elsewhere classified	0.001	0.998	0.000
B33.1 Ross River disease	0.001	0.998	0.000
B35.3 Tinea pedis	0.000	0.998	0.002
D09.7 Carcinoma in situ of other specified sites	0.001	0.998	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.001	0.998	0.000
B25.0 Cytomegaloviral pneumonitis	0.001	0.998	0.000
O62.2 Other uterine inertia	0.000	0.998	0.002
D21.4 Connective and other soft tissue of abdomen	0.001	0.998	0.000
H18.6 Keratoconus	0.000	0.998	0.002
S20.8 Superficial injuries of other and unspecified parts of thorax	0.002	0.998	0.000
B25.8 Other cytomegaloviral diseases	0.001	0.998	0.000
D09.3 Thyroid and other endocrine glands	0.001	0.998	0.000
D09.2 Eye	0.001	0.998	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.998	0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.000	0.999	0.001
O62.3 Precipitate labour	0.000	0.999	0.001
T40.4 Other synthetic narcotics	0.001	0.999	0.000
H35.6 Retinal haemorrhage	0.001	0.999	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.999	0.001
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.999	0.001
M60.09 Infective myositis (Site unspecified)	0.001	0.999	0.000
M60.07 Infective myositis (Ankle and foot)	0.001	0.999	0.000
M60.06 Infective myositis (Lower leg)	0.001	0.999	0.000
M60.04 Infective myositis (Hand)	0.001	0.999	0.000
M60.03 Infective myositis (Forearm)	0.001	0.999	0.000
M60.02 Infective myositis (Upper arm)	0.001	0.999	0.000
M60.01 Infective myositis (Shoulder region)	0.001	0.999	0.000
M60.00 Infective myositis (Multiple sites)	0.001	0.999	0.000
B33.2 Viral carditis	0.001	0.999	0.000
M94 Other disorders of cartilage	0.000	0.999	0.001
T40.6 Other and unspecified narcotics	0.001	0.999	0.000
D21.9 Connective and other soft tissue, unspecified	0.001	0.999	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.000	0.999	0.001
D09.1 Other and unspecified urinary organs	0.001	0.999	0.000
S01.7 Multiple open wounds of head	0.001	0.999	0.000
H80 Otosclerosis	0.001	0.999	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.999	0.001
H80.0 Otosclerosis involving oval window, nonobliterative	0.001	0.999	0.000
M75.2 Bicipital tendinitis	0.001	0.999	0.000
N80.1 Endometriosis of ovary	0.001	0.999	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.000	0.999	0.001
F32.1 Moderate depressive episode	0.001	0.999	0.000
H53.8 Other visual disturbances	0.001	0.999	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.001	0.999	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.999	0.000
H18 Other disorders of cornea	0.000	0.999	0.001
M40.24 Other and unspecified kyphosis (Thoracic region)	0.001	0.999	0.000
H18.7 Other corneal deformities	0.000	0.999	0.001
K06.1 Gingival enlargement	0.000	0.999	0.001
O62 Abnormalities of forces of labour	0.000	0.999	0.001
O62.9 Abnormality of forces of labour, unspecified	0.000	0.999	0.001
M41.92 Scoliosis, unspecified (Cervical region)	0.001	0.999	0.000
I97.0 Postcardiotomy syndrome	0.001	0.999	0.000
M94.3 Chondrolysis	0.000	0.999	0.001
M94.1 Relapsing polychondritis	0.000	0.999	0.001
C48.0 Retroperitoneum	0.001	0.999	0.000
D33.3 Cranial nerves	0.001	0.999	0.000
H18.0 Corneal pigmentations and deposits	0.000	0.999	0.001
H80.8 Other otosclerosis	0.001	0.999	0.000
H80.2 Cochlear otosclerosis	0.001	0.999	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.001	0.999	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.000	0.999	0.001
M40.26 Other and unspecified kyphosis (Lumbar region)	0.001	0.999	0.000
D00-D09 In situ neoplasms	0.001	0.999	0.000
M41.9 Scoliosis, unspecified	0.001	0.999	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.001	0.999	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.999	0.001
B00.9 Herpesviral infection, unspecified	0.001	0.999	0.000
I67.2 Cerebral atherosclerosis	0.000	0.999	0.001
I97.2 Postmastectomy lymphoedema syndrome	0.001	0.999	0.000
M40.2 Other and unspecified kyphosis	0.001	0.999	0.000
O62.8 Other abnormalities of forces of labour	0.000	0.999	0.001
Y65.4 Failure to introduce or to remove other tube or instrument	0.000	0.999	0.001
M40.29 Other and unspecified kyphosis (Site unspecified)	0.001	0.999	0.000
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.001	0.999	0.000
M40.22 Other and unspecified kyphosis (Cervical region)	0.001	0.999	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M94.19 Relapsing polychondritis (Site unspecified)	0.000	0.999	0.001
M94.18 Relapsing polychondritis (Other)	0.000	0.999	0.001
M94.17 Relapsing polychondritis (Ankle and foot)	0.000	0.999	0.001
M94.16 Relapsing polychondritis (Lower leg)	0.000	0.999	0.001
M94.15 Relapsing polychondritis (Pelvic region and thigh)	0.000	0.999	0.001
M94.14 Relapsing polychondritis (Hand)	0.000	0.999	0.001
M94.13 Relapsing polychondritis (Forearm)	0.000	0.999	0.001
M94.12 Relapsing polychondritis (Upper arm)	0.000	0.999	0.001
M94.11 Relapsing polychondritis (Shoulder region)	0.000	0.999	0.001
M94.10 Relapsing polychondritis (Multiple sites)	0.000	0.999	0.001
M94.39 Chondrolysis (Site unspecified)	0.000	0.999	0.001
M94.38 Chondrolysis (Other)	0.000	0.999	0.001
M94.37 Chondrolysis (Ankle and foot)	0.000	0.999	0.001
M94.36 Chondrolysis (Lower leg)	0.000	0.999	0.001
M94.35 Chondrolysis (Pelvic region and thigh)	0.000	0.999	0.001
M94.34 Chondrolysis (Hand)	0.000	0.999	0.001
M94.33 Chondrolysis (Forearm)	0.000	0.999	0.001
M94.32 Chondrolysis (Upper arm)	0.000	0.999	0.001
M94.31 Chondrolysis (Shoulder region)	0.000	0.999	0.001
M94.30 Chondrolysis (Multiple sites)	0.000	0.999	0.001
S82.30 Fracture of lower end of tibia (closed)	0.001	0.999	0.000
M94.9 Disorder of cartilage, unspecified	0.000	0.999	0.001
X67.9 Unspecified place	0.001	0.999	0.000
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.000	0.999	0.001
M94.07 Chondrocostal junction syndrome [Tietze]-Ankle/foot	0.000	0.999	0.001
M94.06 Chondrocostal junction syndrome [Tietze]-Lower leg	0.000	0.999	0.001
M94.05 Chondrocostal junction syndrome [Tietze]-Pelvic/thigh	0.000	0.999	0.001
M94.04 Chondrocostal junction syndrome [Tietze]-Hand	0.000	0.999	0.001
M94.03 Chondrocostal junction syndrome [Tietze]-Forearm	0.000	0.999	0.001
M94.02 Chondrocostal junction syndrome [Tietze]-Upper arm	0.000	0.999	0.001
M94.01 Chondrocostal junction syndrome [Tietze]-Shldr region	0.000	0.999	0.001
M94.00 Chondrocostal junction syndrome [Tietze]-Mult sites	0.000	0.999	0.001
G06.0 Intracranial abscess and granuloma	0.001	0.999	0.000
M23.3 Other meniscus derangements	0.001	0.999	0.000
O62.0 Primary inadequate contractions	0.000	0.999	0.001
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.999	0.001
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.999	0.001
D68.9 Coagulation defect, unspecified	0.001	0.999	0.000
H18.3 Changes in corneal membranes	0.000	0.999	0.001
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.999	0.001
S21.1 Open wound of front wall of thorax	0.000	0.999	0.001
S62.2 Fracture of first metacarpal bone	0.000	0.999	0.001
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.001	0.999	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.001	0.999	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations