TreeWAS – Variant ID: rs2489715

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10 Insulin-dependent diabetes mellitus	0.000	0.004	0.996
E10-E14 Diabetes mellitus	0.000	0.012	0.988
E11 Non-insulin-dependent diabetes mellitus	0.000	0.029	0.971
E14 Unspecified diabetes mellitus	0.000	0.030	0.970
E10.9 Without complications	0.000	0.037	0.963
E10.3 With ophthalmic complications	0.000	0.038	0.962
E14.3 With ophthalmic complications	0.000	0.064	0.936
E11.4 With neurological complications	0.000	0.072	0.928
E10.6 With other specified complications	0.000	0.088	0.912
E10.5 With peripheral circulatory complications	0.000	0.089	0.911
E10.0 With coma	0.000	0.107	0.893
E10.4 With neurological complications	0.000	0.118	0.882
E11.3 With ophthalmic complications	0.000	0.123	0.877
E10.2 With renal complications	0.000	0.135	0.865
E11.0 With coma	0.000	0.157	0.843
E11.2 With renal complications	0.000	0.182	0.818
E10.1 With ketoacidosis	0.000	0.186	0.814
E14.6 With other specified complications	0.000	0.207	0.793
E14.1 With ketoacidosis	0.000	0.225	0.775
E14.2 Withrenal complications	0.000	0.230	0.770
E11.5 With peripheral circulatory complications	0.000	0.248	0.752
E11.6 With other specified complications	0.000	0.262	0.738
E14.5 With peripheral circulatory complications	0.000	0.270	0.730
E14.8 With unspecified complications	0.000	0.285	0.715
E12 Malnutrition-related diabetes mellitus	0.000	0.291	0.708
E11.7 With multiple complications	0.000	0.304	0.696
E14.7 With multiple complications	0.000	0.305	0.695
E14.0 With coma	0.000	0.305	0.695
E14.4 With neurological complications	0.000	0.328	0.672
E10.8 With unspecified complications	0.000	0.349	0.651
E10.7 With multiple complications	0.000	0.352	0.648
E11.1 With ketoacidosis	0.000	0.397	0.603
E14.9 Without complications	0.000	0.400	0.600
E13 Other specified diabetes mellitus	0.000	0.405	0.595
E11.8 With unspecified complications	0.000	0.420	0.580
E12.9 Without complications	0.000	0.492	0.508
E12.8 With unspecified complications	0.000	0.492	0.508
E12.7 With multiple complications	0.000	0.492	0.508
E12.6 With other specified complications	0.000	0.492	0.508
E12.5 With peripheral circulatory complications	0.000	0.492	0.508
E12.4 With neurological complications	0.000	0.492	0.508
E12.3 With ophthalmic complications	0.000	0.492	0.508
E12.2 With renal complications	0.000	0.492	0.508
E12.1 With ketoacidosis	0.000	0.492	0.508
E12.0 With coma	0.000	0.492	0.508
E13.8 With unspecified complications	0.000	0.573	0.427
E13.7 With multiple complications	0.000	0.573	0.427
E13.6 With other specified complications	0.000	0.573	0.427
E13.5 With peripheral circulatory complications	0.000	0.573	0.427
E13.4 With neurological complications	0.000	0.573	0.427
E13.2 With renal complications	0.000	0.573	0.427
E13.1 With ketoacidosis	0.000	0.573	0.427
E13.0 With coma	0.000	0.573	0.427
E13.3 With ophthalmic complications	0.000	0.619	0.380
E13.9 Without complications	0.000	0.626	0.374
H35.8 Other specified retinal disorders	0.000	0.731	0.269
E11.9 Without complications	0.000	0.750	0.250
H35 Other retinal disorders	0.000	0.756	0.244
H35.2 Other proliferative retinopathy	0.000	0.765	0.235
H35.0 Background retinopathy and retinal vascular changes	0.000	0.794	0.206
H35.9 Retinal disorder, unspecified	0.000	0.795	0.205
H30-H36 Disorders of choroid and retina	0.000	0.810	0.190
H36 Retinal disorders in diseases classified elsewhere	0.000	0.816	0.184
H36.0 Diabetic retinopathy	0.000	0.820	0.180
H35.1 Retinopathy of prematurity	0.000	0.825	0.175
H35.5 Hereditary retinal dystrophy	0.000	0.830	0.170
H35.7 Separation of retinal layers	0.000	0.833	0.167
H34 Retinal vascular occlusions	0.000	0.849	0.151
H31 Other disorders of choroid	0.000	0.851	0.149
H30 Chorioretinal inflammation	0.000	0.858	0.142
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.863	0.137
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.868	0.132
H35.3 Degeneration of macula and posterior pole	0.000	0.871	0.129
H34.1 Central retinal artery occlusion	0.000	0.876	0.123
H31.0 Chorioretinal scars	0.000	0.881	0.119
H31.3 Choroidal haemorrhage and rupture	0.000	0.881	0.119
H34.8 Other retinal vascular occlusions	0.000	0.881	0.119
H31.8 Other specified disorders of choroid	0.000	0.882	0.118
H35.6 Retinal haemorrhage	0.000	0.885	0.115
H30.2 Posterior cyclitis	0.000	0.890	0.110
H34.0 Transient retinal artery occlusion	0.000	0.892	0.108
H31.4 Choroidal detachment	0.000	0.893	0.107
H31.2 Hereditary choroidal dystrophy	0.000	0.893	0.107
H34.9 Retinal vascular occlusion, unspecified	0.000	0.895	0.105
H30.8 Other chorioretinal inflammations	0.000	0.898	0.102
H30.1 Disseminated chorioretinal inflammation	0.000	0.898	0.102
H30.0 Focal chorioretinal inflammation	0.000	0.898	0.102
H30.9 Chorioretinal inflammation, unspecified	0.000	0.900	0.100
H31.9 Disorder of choroid, unspecified	0.000	0.901	0.099
H35.4 Peripheral retinal degeneration	0.000	0.902	0.098
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.000	0.902	0.098
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.000	0.902	0.098
H34.2 Other retinal artery occlusions	0.000	0.903	0.097
H31.1 Choroidal degeneration	0.000	0.916	0.084
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.926	0.074
E20-E35 Disorders of other endocrine glands	0.000	0.931	0.069
E29 Testicular dysfunction	0.000	0.934	0.066
E27 Other disorders of adrenal gland	0.000	0.935	0.065
E29.1 Testicular hypofunction	0.000	0.935	0.065
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.936	0.064
E27.1 Primary adrenocortical insufficiency	0.000	0.942	0.058
E16 Other disorders of pancreatic internal secretion	0.000	0.943	0.057
E27.9 Disorder of adrenal gland, unspecified	0.000	0.943	0.057
E26 Hyperaldosteronism	0.000	0.946	0.054
E22 Hyperfunction of pituitary gland	0.000	0.947	0.053
E28 Ovarian dysfunction	0.000	0.948	0.052
E16.2 Hypoglycaemia, unspecified	0.000	0.949	0.051
E25 Adrenogenital disorders	0.000	0.950	0.050
E23 Hypofunction and other disorders of pituitary gland	0.000	0.950	0.050
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.950	0.050
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.950	0.050
E30 Disorders of puberty, not elsewhere classified	0.000	0.950	0.050
E27.2 Addisonian crisis	0.000	0.951	0.049
E31 Polyglandular dysfunction	0.000	0.951	0.049
E32 Diseases of thymus	0.000	0.952	0.047
E29.8 Other testicular dysfunction	0.000	0.952	0.047
E29.0 Testicular hyperfunction	0.000	0.952	0.047
E22.1 Hyperprolactinaemia	0.000	0.953	0.047
E27.5 Adrenomedullary hyperfunction	0.000	0.953	0.047
E27.0 Other adrenocortical overactivity	0.000	0.953	0.047
E15 Nondiabetic hypoglycaemic coma	0.000	0.954	0.046
E20 Hypoparathyroidism	0.000	0.954	0.045
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.956	0.044
E29.9 Testicular dysfunction, unspecified	0.000	0.956	0.043
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.957	0.043
E27.8 Other specified disorders of adrenal gland	0.000	0.957	0.043
E26.0 Primary hyperaldosteronism	0.000	0.958	0.041
E26.9 Hyperaldosteronism, unspecified	0.000	0.959	0.041
E23.6 Other disorders of pituitary gland	0.000	0.959	0.041
E24 Cushing's syndrome	0.000	0.959	0.041
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.959	0.041
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.959	0.041
E16.4 Abnormal secretion of gastrin	0.000	0.959	0.041
E16.3 Increased secretion of glucagon	0.000	0.959	0.041
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.959	0.040
E28.2 Polycystic ovarian syndrome	0.000	0.960	0.040
E16.1 Other hypoglycaemia	0.000	0.960	0.040
E26.8 Other hyperaldosteronism	0.000	0.961	0.039
E26.1 Secondary hyperaldosteronism	0.000	0.961	0.039
E22.8 Other hyperfunction of pituitary gland	0.000	0.961	0.038
E40-E46 Malnutrition	0.000	0.962	0.038
E23.0 Hypopituitarism	0.000	0.962	0.038
E28.9 Ovarian dysfunction, unspecified	0.000	0.962	0.038
E28.8 Other ovarian dysfunction	0.000	0.962	0.038
E28.3 Primary ovarian failure	0.000	0.962	0.038
E28.1 Androgen excess	0.000	0.962	0.038
E28.0 Oestrogen excess	0.000	0.962	0.038
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.963	0.037
E34 Other endocrine disorders	0.000	0.963	0.036
E23.7 Disorder of pituitary gland, unspecified	0.000	0.963	0.036
E25.9 Adrenogenital disorder, unspecified	0.000	0.964	0.036
E25.8 Other adrenogenital disorders	0.000	0.964	0.036
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.964	0.036
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.964	0.036
E23.1 Drug-induced hypopituitarism	0.000	0.964	0.036
E30.9 Disorder of puberty, unspecified	0.000	0.964	0.036
E30.8 Other disorders of puberty	0.000	0.964	0.036
E30.1 Precocious puberty	0.000	0.964	0.036
E30.0 Delayed puberty	0.000	0.964	0.036
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.964	0.036
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.964	0.036
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.964	0.036
E31.9 Polyglandular dysfunction, unspecified	0.000	0.965	0.035
E31.8 Other polyglandular dysfunction	0.000	0.965	0.035
E31.1 Polyglandular hyperfunction	0.000	0.965	0.035
E32.1 Abscess of thymus	0.000	0.966	0.034
E32.0 Persistent hyperplasia of thymus	0.000	0.966	0.034
E31.0 Autoimmune polyglandular failure	0.000	0.966	0.034
E32.9 Disease of thymus, unspecified	0.000	0.966	0.034
E20.0 Idiopathic hypoparathyroidism	0.000	0.967	0.033
E20.8 Other hypoparathyroidism	0.000	0.967	0.032
E32.8 Other diseases of thymus	0.000	0.967	0.032
E20.9 Hypoparathyroidism, unspecified	0.000	0.968	0.032
E24.0 Pituitary-dependent Cushing's disease	0.000	0.968	0.032
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.968	0.032
E65-E68 Obesity and other hyperalimentation	0.000	0.968	0.031
H33 Retinal detachments and breaks	0.000	0.969	0.031
E24.8 Other Cushing's syndrome	0.000	0.970	0.030
E20.1 Pseudohypoparathyroidism	0.000	0.970	0.030
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.970	0.030
E24.3 Ectopic ACTH syndrome	0.000	0.970	0.030
E24.1 Nelson's syndrome	0.000	0.970	0.030
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.972	0.027
E45 Retarded development following protein-energy malnutrition	0.000	0.972	0.027
E43 Unspecified severe protein-energy malnutrition	0.000	0.972	0.027
E42 Marasmic kwashiorkor	0.000	0.972	0.027
E41 Nutritional marasmus	0.000	0.972	0.027
E40 Kwashiorkor	0.000	0.972	0.027
E22.0 Acromegaly and pituitary gigantism	0.000	0.972	0.028
E34.3 Short stature, not elsewhere classified	0.000	0.973	0.027
E24.2 Drug-induced Cushing's syndrome	0.000	0.973	0.026
E34.5 Androgen resistance syndrome	0.000	0.973	0.026
E34.4 Constitutional tall stature	0.000	0.973	0.026
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.973	0.026
E34.1 Other hypersecretion of intestinal hormones	0.000	0.973	0.026
E23.2 Diabetes insipidus	0.000	0.975	0.025
E34.8 Other specified endocrine disorders	0.000	0.975	0.024
H33.5 Other retinal detachments	0.000	0.975	0.025
E34.0 Carcinoid syndrome	0.000	0.975	0.024
E67 Other hyperalimentation	0.000	0.977	0.023
E68 Sequelae of hyperalimentation	0.000	0.977	0.023
E21.2 Other hyperparathyroidism	0.000	0.977	0.023
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.978	0.022
E21.4 Other specified disorders of parathyroid gland	0.000	0.978	0.022
E50-E64 Other nutritional deficiencies	0.000	0.978	0.022
E21.3 Hyperparathyroidism, unspecified	0.000	0.978	0.022
E00-E07 Disorders of thyroid gland	0.000	0.979	0.021
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.979	0.020
E44.1 Mild protein-energy malnutrition	0.000	0.980	0.020
E44.0 Moderate protein-energy malnutrition	0.000	0.980	0.020
E24.9 Cushing's syndrome, unspecified	0.000	0.980	0.020
E34.9 Endocrine disorder, unspecified	0.000	0.981	0.019
H33.2 Serous retinal detachment	0.000	0.982	0.018
H33.4 Traction detachment of retina	0.000	0.982	0.018
E06 Thyroiditis	0.000	0.983	0.017
E21.0 Primary hyperparathyroidism	0.000	0.983	0.017
E54 Ascorbic acid deficiency	0.000	0.983	0.017
E58 Dietary calcium deficiency	0.000	0.983	0.017
E67.8 Other specified hyperalimentation	0.000	0.983	0.016
E67.3 Hypervitaminosis D	0.000	0.983	0.016
E67.2 Megavitamin-B6 syndrome	0.000	0.983	0.016
E67.1 Hypercarotenaemia	0.000	0.983	0.016
E67.0 Hypervitaminosis A	0.000	0.983	0.016
E66 Obesity	0.000	0.984	0.016
N80.0 Endometriosis of uterus	0.000	0.984	0.016
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.984	0.016
E50 Vitamin A deficiency	0.000	0.984	0.016
E60 Dietary zinc deficiency	0.000	0.984	0.016
E59 Dietary selenium deficiency	0.000	0.984	0.016
E52 Niacin deficiency [pellagra]	0.000	0.984	0.016
E06.3 Autoimmune thyroiditis	0.000	0.984	0.016
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.984	0.015
E56 Other vitamin deficiencies	0.000	0.984	0.015
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.984	0.015
E00 Congenital iodine-deficiency syndrome	0.000	0.984	0.015
E51 Thiamine deficiency	0.000	0.984	0.015
E63 Other nutritional deficiencies	0.000	0.985	0.015
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.985	0.015
E65 Localised adiposity	0.000	0.986	0.014
H33.1 Retinoschisis and retinal cysts	0.000	0.986	0.013
E46 Unspecified protein-energy malnutrition	0.001	0.987	0.013
H33.0 Retinal detachment with retinal break	0.000	0.987	0.013
E04 Other non-toxic goitre	0.000	0.987	0.013
E06.5 Other chronic thyroiditis	0.000	0.987	0.013
E06.1 Subacute thyroiditis	0.000	0.987	0.013
E06.4 Drug-induced thyroiditis	0.000	0.987	0.012
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.987	0.012
E06.0 Acute thyroiditis	0.000	0.987	0.012
E66.0 Obesity due to excess calories	0.000	0.987	0.012
E03 Other hypothyroidism	0.000	0.988	0.012
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.988	0.012
H33.3 Retinal breaks without detachment	0.000	0.988	0.012
E66.1 Drug-induced obesity	0.000	0.988	0.012
E55 Vitamin D deficiency	0.000	0.988	0.012
E50.9 Vitamin A deficiency, unspecified	0.000	0.988	0.011
E50.8 Other manifestations of vitamin A deficiency	0.000	0.988	0.011
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.988	0.011
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.988	0.011
E50.5 Vitamin A deficiency with night blindness	0.000	0.988	0.011
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.988	0.011
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.988	0.011
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.988	0.011
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.988	0.011
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.988	0.011
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.988	0.011
E64.8 Sequelae of other nutritional deficiencies	0.000	0.988	0.011
E64.3 Sequelae of rickets	0.000	0.988	0.011
E64.2 Sequelae of vitamin C deficiency	0.000	0.988	0.011
E64.1 Sequelae of vitamin A deficiency	0.000	0.988	0.011
E64.0 Sequelae of protein-energy malnutrition	0.000	0.988	0.011
E61 Deficiency of other nutrient elements	0.000	0.988	0.011
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.989	0.011
E56.9 Vitamin deficiency, unspecified	0.000	0.989	0.011
E56.8 Deficiency of other vitamins	0.000	0.989	0.011
E56.0 Deficiency of vitamin E	0.000	0.989	0.011
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.989	0.011
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.989	0.011
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.989	0.011
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.989	0.011
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.989	0.011
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.989	0.011
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.989	0.011
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.989	0.011
E51.9 Thiamine deficiency, unspecified	0.000	0.989	0.011
E51.8 Other manifestations of thiamine deficiency	0.000	0.989	0.011
E51.1 Beriberi	0.000	0.989	0.011
E04.2 Non-toxic multinodular goitre	0.000	0.989	0.011
E07 Other disorders of thyroid	0.000	0.989	0.011
E63.8 Other specified nutritional deficiencies	0.000	0.989	0.011
E63.1 Imbalance of constituents of food intake	0.000	0.989	0.011
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.989	0.011
E56.1 Deficiency of vitamin K	0.000	0.989	0.011
E51.2 Wernicke's encephalopathy	0.000	0.989	0.011
E03.8 Other specified hypothyroidism	0.000	0.989	0.010
E63.9 Nutritional deficiency, unspecified	0.000	0.990	0.010
E03.1 Congenital hypothyroidism without goitre	0.000	0.990	0.010
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.990	0.010
E04.8 Other specified non-toxic goitre	0.000	0.990	0.010
E04.9 Non-toxic goitre, unspecified	0.000	0.991	0.009
E04.0 Non-toxic diffuse goitre	0.000	0.991	0.009
E03.5 Myxoedema coma	0.000	0.991	0.009
E03.4 Atrophy of thyroid (acquired)	0.000	0.991	0.009
E03.3 Postinfectious hypothyroidism	0.000	0.991	0.009
E06.9 Thyroiditis, unspecified	0.000	0.991	0.009
E55.0 Rickets, active	0.000	0.991	0.009
E61.9 Deficiency of nutrient element, unspecified	0.000	0.991	0.008
E61.8 Deficiency of other specified nutrient elements	0.000	0.991	0.008
E61.7 Deficiency of multiple nutrient elements	0.000	0.991	0.008
E61.6 Vanadium deficiency	0.000	0.991	0.008
E61.5 Molybdenum deficiency	0.000	0.991	0.008
E61.4 Chromium deficiency	0.000	0.991	0.008
E61.3 Manganese deficiency	0.000	0.991	0.008
E61.0 Copper deficiency	0.000	0.991	0.008
E66.8 Other obesity	0.000	0.992	0.008
E07.1 Dyshormogenetic goitre	0.000	0.992	0.008
E07.0 Hypersecretion of calcitonin	0.000	0.992	0.008
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.992	0.008
E61.2 Magnesium deficiency	0.000	0.992	0.008
E07.8 Other specified disorders of thyroid	0.000	0.992	0.008
E53 Deficiency of other B group vitamins	0.000	0.992	0.007
R03.1 Nonspecific low blood-pressure reading	0.008	0.992	0.000
N41.1 Chronic prostatitis	0.007	0.993	0.000
Y84.6 Urinary catheterisation	0.000	0.993	0.007
Y84.8 Other medical procedures	0.000	0.993	0.007
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.993	0.007
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.006	0.994	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.994	0.006
M47.92 Spondylosis, unspecified (Cervical region)	0.006	0.994	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.006	0.994	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.994	0.006
E53.1 Pyridoxine deficiency	0.000	0.994	0.005
E53.0 Riboflavin deficiency	0.000	0.994	0.005
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.994	0.006
Y84.3 Shock therapy	0.000	0.994	0.006
H54.7 Unspecified visual loss	0.000	0.995	0.005
E61.1 Iron deficiency	0.000	0.995	0.005
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.995	0.005
C15.9 Oesophagus, unspecified	0.000	0.995	0.005
Y84.7 Blood-sampling	0.000	0.995	0.005
Y84.5 Insertion of gastric or duodenal sound	0.000	0.995	0.005
E07.9 Disorder of thyroid, unspecified	0.000	0.995	0.005
Y84.9 Medical procedure, unspecified	0.000	0.995	0.005
E55.9 Vitamin D deficiency, unspecified	0.000	0.995	0.005
Y84.1 Kidney dialysis	0.000	0.995	0.005
Y84.4 Aspiration of fluid	0.000	0.995	0.005
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.995	0.005
E04.1 Non-toxic single thyroid nodule	0.000	0.995	0.004
E53.9 Vitamin B deficiency, unspecified	0.001	0.996	0.004
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.996	0.004
I74 Arterial embolism and thrombosis	0.000	0.996	0.004
E05.5 Thyroid crisis or storm	0.000	0.996	0.004
E05.4 Thyrotoxicosis factitia	0.000	0.996	0.004
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.996	0.004
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.996	0.004
J69.0 Pneumonitis due to food and vomit	0.004	0.996	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.996	0.004
C15.4 Middle third of oesophagus	0.000	0.996	0.004
C15.5 Lower third of oesophagus	0.000	0.996	0.004
C18.0 Caecum	0.000	0.996	0.004
J43.9 Emphysema, unspecified	0.004	0.996	0.000
E05.8 Other thyrotoxicosis	0.000	0.996	0.004
I74.5 Embolism and thrombosis of iliac artery	0.000	0.996	0.004
H54 Blindness and low vision	0.000	0.996	0.004
T14.0 Superficial injury of unspecified body region	0.000	0.996	0.004
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.996	0.004
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.996	0.004
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.996	0.003
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.997	0.003
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.997	0.003
H54.0 Blindness, both eyes	0.000	0.997	0.003
T82.3 Mechanical complication of other vascular grafts	0.000	0.997	0.003
H54.2 Low vision, both eyes	0.000	0.997	0.003
C15.8 Overlapping lesion of oesophagus	0.000	0.997	0.003
C15.2 Abdominal part of oesophagus	0.000	0.997	0.003
C15.0 Cervical part of oesophagus	0.000	0.997	0.003
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.997	0.003
C15.1 Thoracic part of oesophagus	0.000	0.997	0.003
N21.0 Calculus in bladder	0.000	0.997	0.003
H54.6 Unqualified visual loss, one eye	0.000	0.997	0.003
C15.3 Upper third of oesophagus	0.000	0.997	0.003
H54.5 Low vision, one eye	0.000	0.997	0.003
H54.3 Unqualified visual loss, both eyes	0.000	0.997	0.003
H54.1 Blindness, one eye, low vision, other eye	0.000	0.997	0.003
I95.2 Hypotension due to drugs	0.000	0.997	0.003
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.997	0.003
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.997	0.003
H54.4 Blindness, one eye	0.000	0.997	0.003
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.997	0.003
H61.2 Impacted cerumen	0.003	0.997	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.997	0.003
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.997	0.002
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.997	0.002
I74.8 Embolism and thrombosis of other arteries	0.000	0.997	0.002
T82.1 Mechanical complication of cardiac electronic device	0.000	0.997	0.002
Y84.0 Cardiac catheterisation	0.000	0.997	0.002
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
D22.6 Melanocytic naevi of upper limb, including shoulder	0.002	0.998	0.000
J32.0 Chronic maxillary sinusitis	0.002	0.998	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.998	0.002
K25.4 Chronic or unspecified with haemorrhage	0.000	0.998	0.002
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
T14 Injury of unspecified body region	0.000	0.998	0.002
Y60.0 During surgical operation	0.002	0.998	0.000
G25 Other extrapyramidal and movement disorders	0.000	0.998	0.002
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.998	0.002
S06.5 Traumatic subdural haemorrhage	0.002	0.998	0.000
S06.3 Focal brain injury	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.002	0.998	0.000
G25.3 Myoclonus	0.000	0.998	0.002
S06.8 Other intracranial injuries	0.002	0.998	0.000
S06 Intracranial injury	0.002	0.998	0.000
H53-H54 Visual disturbances and blindness	0.000	0.998	0.002
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
J69 Pneumonitis due to solids and liquids	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
K25.5 Chronic or unspecified with perforation	0.000	0.998	0.002
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.998	0.002
I12.0 Hypertensive renal disease with renal failure	0.000	0.998	0.002
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.998	0.002
I87.1 Compression of vein	0.000	0.998	0.002
T14.6 Injury of tendons and muscles of unspecified body region	0.000	0.998	0.002
J43 Emphysema	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
G25.1 Drug-induced tremor	0.000	0.998	0.002
E05.9 Thyrotoxicosis, unspecified	0.000	0.998	0.002
R74.8 Abnormal levels of other serum enzymes	0.000	0.998	0.002
T14.2 Fracture of unspecified body region	0.000	0.998	0.002
T14.9 Injury, unspecified	0.000	0.998	0.002
T14.8 Other injuries of unspecified body region	0.000	0.998	0.002
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.000	0.998	0.002
T14.5 Injury of blood vessel(s) of unspecified body region	0.000	0.998	0.002
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.000	0.998	0.002
N41 Inflammatory diseases of prostate	0.002	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.998	0.002
G25.4 Drug-induced chorea	0.000	0.998	0.002
T14.4 Injury of nerve(s) of unspecified body region	0.000	0.998	0.002
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.998	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.002	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
K25 Gastric ulcer	0.000	0.998	0.002
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.998	0.002
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
T14.1 Open wound of unspecified body region	0.000	0.998	0.002
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.002	0.998	0.000
J69.1 Pneumonitis due to oils and essences	0.002	0.998	0.000
G25.2 Other specified forms of tremor	0.000	0.998	0.002
H53.4 Visual field defects	0.000	0.998	0.002
N41.8 Other inflammatory diseases of prostate	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
G25.5 Other chorea	0.000	0.998	0.001
H61.8 Other specified disorders of external ear	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.998	0.002
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.002	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.998	0.001
J43.1 Panlobular emphysema	0.002	0.998	0.000
J43.0 MacLeod's syndrome	0.002	0.998	0.000
K07.3 Anomalies of tooth position	0.000	0.998	0.002
M45.X9 Ankylosing spondylitis (Site unspecified)	0.002	0.998	0.000
H61 Other disorders of external ear	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
J43.2 Centrilobular emphysema	0.002	0.998	0.000
W19.3 Sports and athletics area	0.000	0.998	0.002
X68.9 Unspecified place	0.002	0.998	0.000
Y60.5 During heart catheterisation	0.002	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.001	0.998	0.000
S62.60 Fracture of other finger (closed)	0.000	0.998	0.002
J43.8 Other emphysema	0.002	0.998	0.000
J69.8 Pneumonitis due to other solids and liquids	0.001	0.998	0.000
K60.2 Anal fissure, unspecified	0.002	0.998	0.000
N41.2 Abscess of prostate	0.002	0.998	0.000
S06.0 Concussion	0.002	0.998	0.000
T14.21 Fracture of unspecified body region (open)	0.000	0.998	0.001
T14.20 Fracture of unspecified body region (closed)	0.000	0.998	0.001
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.998	0.002
H17.9 Corneal scar and opacity, unspecified	0.000	0.998	0.002
O36.8 Maternal care for other specified foetal problems	0.000	0.998	0.002
N41.3 Prostatocystitis	0.001	0.998	0.000
S06.4 Epidural haemorrhage	0.001	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
Y60.8 During other surgical and medical care	0.001	0.998	0.000
K25.2 Acute with both haemorrhage and perforation	0.000	0.998	0.001
O36.5 Maternal care for poor foetal growth	0.000	0.998	0.002
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.001	0.998	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.001	0.998	0.000
K82.8 Other specified diseases of gallbladder	0.000	0.998	0.002
F20 Schizophrenia	0.000	0.998	0.002
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.998	0.002
H17.8 Other corneal scars and opacities	0.000	0.998	0.001
F20.8 Other schizophrenia	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations