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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2496644
log Bayes Factor = 15.9721
Chromosome 6   position 41,482,745  (GRCh37) Explore rs2496644 on Ensembl!
Variant rs2496644 is part of Cluster X0106

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.997 0.003 0.000
N40-N51 Diseases of male genital organs
0.996 0.004 0.000
Z51 Other medical care
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.992 0.008 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.988 0.012 0.000
D10-D36 Benign neoplasms
0.987 0.013 0.000
Z51.0 Radiotherapy session
0.981 0.019 0.000
N40 Hyperplasia of prostate
0.980 0.020 0.000
M05-M14 Inflammatory polyarthropathies
0.978 0.022 0.000
Chapter VIII Diseases of the ear and mastoid process
0.978 0.022 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.975 0.025 0.000
Z51.5 Palliative care
0.974 0.026 0.000
C15-C26 Malignant neoplasms of digestive organs
0.974 0.026 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.974 0.026 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.970 0.030 0.000
M45-M49 Spondylopathies
0.969 0.031 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.966 0.034 0.000
M06 Other rheumatoid arthritis
0.963 0.037 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.962 0.038 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.961 0.039 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.957 0.043 0.000
M06.9 Rheumatoid arthritis, unspecified
0.948 0.052 0.000
M47 Spondylosis
0.943 0.057 0.000
N10-N16 Renal tubulo-interstitial diseases
0.941 0.059 0.000
N60-N64 Disorders of breast
0.940 0.060 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.938 0.062 0.000
Z93 Artificial opening status
0.936 0.064 0.000
C15 Malignant neoplasm of oesophagus
0.923 0.077 0.000
Z87 Personal history of other diseases and conditions
0.923 0.077 0.000
M47.8 Other spondylosis
0.920 0.080 0.000
N13 Obstructive and reflux uropathy
0.919 0.081 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.919 0.081 0.000
N72 Inflammatory disease of cervix uteri
0.918 0.082 0.000
Z51.3 Blood transfusion without reported diagnosis
0.918 0.082 0.000
Z98 Other postsurgical states
0.918 0.082 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.917 0.083 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.916 0.084 0.000
D60-D64 Aplastic and other anaemias
0.913 0.087 0.000
N50 Other disorders of male genital organs
0.912 0.088 0.000
Z45 Adjustment and management of implanted device
0.910 0.090 0.000
H80-H83 Diseases of inner ear
0.901 0.099 0.000
H65-H75 Diseases of middle ear and mastoid
0.900 0.100 0.000
N93 Other abnormal uterine and vaginal bleeding
0.898 0.102 0.000
Z87.1 Personal history of diseases of the digestive system
0.896 0.104 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.893 0.107 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.889 0.111 0.000
C51-C58 Malignant neoplasms of female genital organs
0.889 0.111 0.000
N87 Dysplasia of cervix uteri
0.885 0.115 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.883 0.117 0.000
O60-O75 Complications of labour and delivery
0.880 0.120 0.000
Z97 Presence of other devices
0.876 0.124 0.000
M47.82 Other spondylosis (Cervical region)
0.876 0.124 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.872 0.128 0.000
Chapter XX External causes of morbidity and mortality
0.871 0.129 0.000
Chapter XI Diseases of the digestive system
0.867 0.133 0.000
D24 Benign neoplasm of breast
0.867 0.133 0.000
N64 Other disorders of breast
0.863 0.137 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.863 0.137 0.000
N41 Inflammatory diseases of prostate
0.859 0.141 0.000
N00-N08 Glomerular diseases
0.857 0.143 0.000
Z96 Presence of other functional implants
0.854 0.146 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.854 0.146 0.000
H83 Other diseases of inner ear
0.854 0.146 0.000
S70-S79 Injuries to the hip and thigh
0.854 0.146 0.000
D64 Other anaemias
0.853 0.147 0.000
N93.0 Postcoital and contact bleeding
0.853 0.147 0.000
N99-N99 Other disorders of the genitourinary system
0.852 0.148 0.000
Chapter V Mental and behavioural disorders
0.852 0.148 0.000
M50-M54 Other dorsopathies
0.852 0.148 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.850 0.150 0.000
N13.3 Other and unspecified hydronephrosis
0.849 0.151 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.848 0.152 0.000
N60 Benign mammary dysplasia
0.847 0.153 0.000
Z93.2 Ileostomy status
0.844 0.156 0.000
Z98.0 Intestinal bypass and anastomosis status
0.842 0.158 0.000
O42 Premature rupture of membranes
0.842 0.158 0.000
H72 Perforation of tympanic membrane
0.840 0.160 0.000
C15.9 Oesophagus, unspecified
0.839 0.161 0.000
O36 Maternal care for other known or suspected foetal problems
0.839 0.161 0.000
Z45.8 Adjustment and management of other implanted devices
0.837 0.163 0.000
D12.5 Sigmoid colon
0.836 0.164 0.000
R21 Rash and other nonspecific skin eruption
0.836 0.164 0.000
N17-N19 Renal failure
0.835 0.165 0.000
C16 Malignant neoplasm of stomach
0.833 0.167 0.000
K90-K93 Other diseases of the digestive system
0.832 0.168 0.000
Z80 Family history of malignant neoplasm
0.831 0.169 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.831 0.169 0.000
Z93.6 Other artificial openings of urinary tract status
0.829 0.171 0.000
N48 Other disorders of penis
0.828 0.172 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.827 0.173 0.000
M48 Other spondylopathies
0.823 0.177 0.000
T66-T78 Other and unspecified effects of external causes
0.822 0.178 0.000
H83.0 Labyrinthitis
0.820 0.180 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.820 0.180 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.820 0.180 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.818 0.182 0.000
O48 Prolonged pregnancy
0.817 0.183 0.000
Z83 Family history of other specific disorders
0.816 0.184 0.000
N76 Other inflammation of vagina and vulva
0.816 0.184 0.000
C54 Malignant neoplasm of corpus uteri
0.815 0.185 0.000
Z43 Attention to artificial openings
0.814 0.186 0.000
Z96.0 Presence of urogenital implants
0.812 0.188 0.000
C15.5 Lower third of oesophagus
0.810 0.190 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.810 0.190 0.000
D64.9 Anaemia, unspecified
0.810 0.190 0.000
K50-K52 Noninfective enteritis and colitis
0.809 0.191 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.808 0.192 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.805 0.195 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.804 0.196 0.000
N50.8 Other specified disorders of male genital organs
0.804 0.196 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.803 0.197 0.000
M47.86 Other spondylosis (Lumbar region)
0.802 0.198 0.000
M11 Other crystal arthropathies
0.801 0.199 0.000
R20 Disturbances of skin sensation
0.800 0.200 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.800 0.200 0.000
N87.0 Mild cervical dysplasia
0.798 0.202 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.795 0.205 0.000
Z51.9 Medical care, unspecified
0.794 0.206 0.000
M47.89 Other spondylosis (Site unspecified)
0.793 0.207 0.000
Z97.8 Presence of other specified devices
0.792 0.208 0.000
Z44 Fitting and adjustment of external prosthetic device
0.792 0.208 0.000
D36 Benign neoplasm of other and unspecified sites
0.792 0.208 0.000
T81 Complications of procedures, not elsewhere classified
0.791 0.209 0.000
D12.6 Colon, unspecified
0.790 0.210 0.000
D12.2 Ascending colon
0.788 0.212 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.787 0.213 0.000
M80-M85 Disorders of bone density and structure
0.787 0.213 0.000
D70 Agranulocytosis
0.786 0.214 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.785 0.215 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.785 0.215 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.784 0.216 0.000
Z90.7 Acquired absence of genital organ(s)
0.783 0.217 0.000
R94 Abnormal results of function studies
0.783 0.217 0.000
M06.0 Seronegative rheumatoid arthritis
0.781 0.219 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.780 0.220 0.000
Z90.1 Acquired absence of breast(s)
0.775 0.225 0.000
C60-C63 Malignant neoplasms of male genital organs
0.774 0.226 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.773 0.226 0.000
K92 Other diseases of digestive system
0.772 0.228 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.771 0.229 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.771 0.229 0.000
N50.1 Vascular disorders of male genital organs
0.770 0.230 0.000
D12.8 Rectum
0.769 0.231 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.768 0.232 0.000
D17 Benign lipomatous neoplasm
0.767 0.233 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.766 0.234 0.000
R80 Isolated proteinuria
0.766 0.234 0.000
C21 Malignant neoplasm of anus and anal canal
0.765 0.235 0.000
Z98.1 Arthrodesis status
0.765 0.235 0.000
N86 Erosion and ectropion of cervix uteri
0.765 0.235 0.000
N43 Hydrocele and spermatocele
0.764 0.236 0.000
S40-S49 Injuries to the shoulder and upper arm
0.763 0.237 0.000
C54.1 Endometrium
0.762 0.238 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.762 0.238 0.000
N13.6 Pyonephrosis
0.761 0.239 0.000
S72 Fracture of femur
0.761 0.239 0.000
Z90.5 Acquired absence of kidney
0.759 0.241 0.000
C25 Malignant neoplasm of pancreas
0.759 0.241 0.000
N45 Orchitis and epididymitis
0.758 0.242 0.000
D32 Benign neoplasm of meninges
0.757 0.243 0.000
M40-M43 Deforming dorsopathies
0.756 0.244 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.755 0.245 0.000
M65-M68 Disorders of synovium and tendon
0.755 0.245 0.000
N13.4 Hydroureter
0.753 0.247 0.000
O80-O84 Delivery
0.752 0.247 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.751 0.249 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.750 0.250 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.750 0.250 0.000
N64.8 Other specified disorders of breast
0.749 0.251 0.000
Z94 Transplanted organ and tissue status
0.748 0.252 0.000
N73 Other female pelvic inflammatory diseases
0.747 0.253 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.747 0.253 0.000
M54 Dorsalgia
0.747 0.253 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.746 0.254 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.746 0.254 0.000
N19 Unspecified renal failure
0.745 0.255 0.000
M86-M90 Other osteopathies
0.744 0.256 0.000
N92 Excessive, frequent and irregular menstruation
0.744 0.256 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.743 0.257 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.743 0.257 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.742 0.258 0.000
N30-N39 Other diseases of urinary system
0.741 0.259 0.000
M07 Psoriatic and enteropathic arthropathies
0.740 0.260 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.740 0.260 0.000
H60-H62 Diseases of external ear
0.740 0.260 0.000
N60.8 Other benign mammary dysplasias
0.739 0.261 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.738 0.262 0.000
D25 Leiomyoma of uterus
0.738 0.262 0.000
K50 Crohn's disease [regional enteritis]
0.737 0.263 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.736 0.264 0.000
D22 Melanocytic naevi
0.736 0.264 0.000
Z48 Other surgical follow-up care
0.735 0.264 0.000
D00-D09 In situ neoplasms
0.735 0.265 0.000
K70-K77 Diseases of liver
0.735 0.265 0.000
H90-H95 Other disorders of ear
0.735 0.265 0.000
R87 Abnormal findings in specimens from female genital organs
0.734 0.266 0.000
D34 Benign neoplasm of thyroid gland
0.733 0.267 0.000
S50-S59 Injuries to the elbow and forearm
0.732 0.268 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.731 0.269 0.000
Chapter X Diseases of the respiratory system
0.731 0.269 0.000
D80-D89 Certain disorders involving the immune mechanism
0.730 0.270 0.000
M47.9 Spondylosis, unspecified
0.730 0.270 0.000
R20.2 Paraesthesia of skin
0.730 0.270 0.000
D12.0 Caecum
0.728 0.272 0.000
Z73 Problems related to life-management difficulty
0.728 0.272 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.727 0.273 0.000
C16.0 Cardia
0.726 0.274 0.000
O00-O08 Pregnancy with abortive outcome
0.726 0.274 0.000
N20-N23 Urolithiasis
0.725 0.275 0.000
N80 Endometriosis
0.724 0.276 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.723 0.277 0.000
C20 Malignant neoplasm of rectum
0.723 0.277 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.723 0.277 0.000
Chapter VI Diseases of the nervous system
0.719 0.281 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.719 0.281 0.000
M48.0 Spinal stenosis
0.718 0.282 0.000
N97 Female infertility
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
Z90.0 Acquired absence of part of head and neck
0.717 0.283 0.000
R94.5 Abnormal results of liver function studies
0.717 0.283 0.000
D27 Benign neoplasm of ovary
0.716 0.284 0.000
Z54 Convalescence
0.715 0.285 0.000
Z52 Donors of organs and tissues
0.715 0.285 0.000
Z49 Care involving dialysis
0.715 0.285 0.000
N71 Inflammatory disease of uterus, except cervix
0.715 0.285 0.000
O70 Perineal laceration during delivery
0.715 0.285 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.714 0.286 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.714 0.286 0.000
N46 Male infertility
0.714 0.286 0.000
N44 Torsion of testis
0.714 0.286 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.714 0.286 0.000
N94.1 Dyspareunia
0.714 0.286 0.000
Z51.6 Desensitisation to allergens
0.713 0.286 0.000
T78 Adverse effects, not elsewhere classified
0.712 0.288 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.712 0.288 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
K51 Ulcerative colitis
0.712 0.288 0.000
Z89 Acquired absence of limb
0.711 0.289 0.000
Z84 Family history of other conditions
0.711 0.289 0.000
Z81 Family history of mental and behavioural disorders
0.711 0.289 0.000
O73 Retained placenta and membranes, without haemorrhage
0.711 0.289 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.711 0.289 0.000
D10 Benign neoplasm of mouth and pharynx
0.710 0.290 0.000
D50-D53 Nutritional anaemias
0.710 0.290 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.710 0.290 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.709 0.291 0.000
N94.3 Premenstrual tension syndrome
0.709 0.291 0.000
N41.1 Chronic prostatitis
0.709 0.291 0.000
O85-O92 Complications predominantly related to the puerperium
0.708 0.292 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.708 0.292 0.000
D31 Benign neoplasm of eye and adnexa
0.708 0.292 0.000
D30 Benign neoplasm of urinary organs
0.708 0.292 0.000
D29 Benign neoplasm of male genital organs
0.708 0.292 0.000
D26 Other benign neoplasms of uterus
0.708 0.292 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.708 0.292 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.708 0.292 0.000
D19 Benign neoplasm of mesothelial tissue
0.708 0.292 0.000
D16 Benign neoplasm of bone and articular cartilage
0.708 0.292 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.708 0.292 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.708 0.292 0.000
D11 Benign neoplasm of major salivary glands
0.708 0.292 0.000
Z71.8 Other specified counselling
0.707 0.293 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.707 0.293 0.000
O63 Long labour
0.706 0.294 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.705 0.294 0.000
N94.6 Dysmenorrhoea, unspecified
0.705 0.295 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.704 0.296 0.000
H66 Suppurative and unspecified otitis media
0.703 0.297 0.000
N64.9 Disorder of breast, unspecified
0.701 0.299 0.000
M14 Arthropathies in other diseases classified elsewhere
0.701 0.299 0.000
M12 Other specific arthropathies
0.701 0.299 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.701 0.299 0.000
M08 Juvenile arthritis
0.701 0.299 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.701 0.299 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.701 0.299 0.000
Z72 Problems related to lifestyle
0.701 0.299 0.000
Z45.1 Adjustment and management of infusion pump
0.701 0.299 0.000
H65 Nonsuppurative otitis media
0.699 0.301 0.000
T79-T79 Certain early complications of trauma
0.699 0.301 0.000
T33-T35 Frostbite
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.699 0.301 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.699 0.301 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.699 0.301 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.699 0.301 0.000
T00-T07 Injuries involving multiple body regions
0.699 0.301 0.000
S10-S19 Injuries to the neck
0.699 0.301 0.000
Z96.8 Presence of other specified functional implants
0.699 0.301 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.699 0.301 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.699 0.301 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.699 0.301 0.000
C17 Malignant neoplasm of small intestine
0.699 0.301 0.000
C23 Malignant neoplasm of gallbladder
0.699 0.301 0.000
D55-D59 Haemolytic anaemias
0.698 0.301 0.000
Z51.8 Other specified medical care
0.698 0.302 0.000
Z93.5 Cystostomy status
0.697 0.303 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.697 0.303 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.697 0.303 0.000
Z90.3 Acquired absence of part of stomach
0.697 0.303 0.000
N98 Complications associated with artificial fertilisation
0.695 0.305 0.000
N91 Absent, scanty and rare menstruation
0.695 0.305 0.000
N82 Fistulae involving female genital tract
0.695 0.305 0.000
N96 Habitual aborter
0.695 0.305 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.695 0.305 0.000
D12.4 Descending colon
0.695 0.305 0.000
M49 Spondylopathies in diseases classified elsewhere
0.695 0.305 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.695 0.305 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.694 0.306 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.694 0.306 0.000
Z75 Problems related to medical facilities and other health care
0.693 0.307 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.693 0.307 0.000
N02 Recurrent and persistent haematuria
0.692 0.308 0.000
N60.4 Mammary duct ectasia
0.692 0.308 0.000
Z43.2 Attention to ileostomy
0.691 0.309 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.691 0.309 0.000
M06.8 Other specified rheumatoid arthritis
0.691 0.309 0.000
M06.4 Inflammatory polyarthropathy
0.691 0.309 0.000
M06.3 Rheumatoid nodule
0.691 0.309 0.000
M06.2 Rheumatoid bursitis
0.691 0.309 0.000
M06.1 Adult-onset Still's disease
0.691 0.309 0.000
Z99.1 Dependence on respirator
0.691 0.309 0.000
Z42 Follow-up care involving plastic surgery
0.690 0.310 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.690 0.310 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.690 0.310 0.000
R25 Abnormal involuntary movements
0.690 0.310 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.690 0.310 0.000
M05 Seropositive rheumatoid arthritis
0.689 0.310 0.000
Z90.8 Acquired absence of other organs
0.689 0.311 0.000
Z87.8 Personal history of other specified conditions
0.689 0.311 0.000
S90-S99 Injuries to the ankle and foot
0.689 0.311 0.000
K92.1 Melaena
0.688 0.312 0.000
N64.5 Other signs and symptoms in breast
0.687 0.313 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.687 0.313 0.000
O45 Premature separation of placenta [abruptio placentae]
0.686 0.314 0.000
O44 Placenta praevia
0.686 0.314 0.000
O43 Placental disorders
0.686 0.314 0.000
O41 Other disorders of amniotic fluid and membranes
0.686 0.314 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.686 0.314 0.000
O33 Maternal care for known or suspected disproportion
0.686 0.314 0.000
O31 Complications specific to multiple gestation
0.686 0.314 0.000
O30 Multiple gestation
0.686 0.314 0.000
O40 Polyhydramnios
0.686 0.314 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.685 0.315 0.000
C18 Malignant neoplasm of colon
0.685 0.315 0.000
J20-J22 Other acute lower respiratory infections
0.683 0.317 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.682 0.318 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.680 0.320 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.679 0.320 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.679 0.320 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.679 0.320 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.679 0.320 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.679 0.321 0.000
Z45.2 Adjustment and management of vascular access device
0.678 0.322 0.000
K35-K38 Diseases of appendix
0.678 0.322 0.000
N76.8 Other specified inflammation of vagina and vulva
0.678 0.322 0.000
M13 Other arthritis
0.676 0.323 0.000
M47.2 Other spondylosis with radiculopathy
0.676 0.324 0.000
M47.1 Other spondylosis with myelopathy
0.676 0.324 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.676 0.324 0.000
Z96.7 Presence of other bone and tendon implants
0.676 0.324 0.000
N48.6 Balanitis xerotica obliterans
0.676 0.324 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.675 0.325 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.675 0.325 0.000
N15 Other renal tubulo-interstitial diseases
0.675 0.325 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.675 0.325 0.000
N11 Chronic tubulo-interstitial nephritis
0.675 0.325 0.000
N10 Acute tubulo-interstitial nephritis
0.675 0.325 0.000
M11.2 Other chondrocalcinosis
0.674 0.326 0.000
Z74 Problems related to care-provider dependency
0.674 0.326 0.000
D28.0 Vulva
0.674 0.326 0.000
C73 Malignant neoplasm of thyroid gland
0.674 0.326 0.000
R11 Nausea and vomiting
0.673 0.327 0.000
N17 Acute renal failure
0.673 0.327 0.000
D12.9 Anus and anal canal
0.672 0.327 0.000
D12.1 Appendix
0.672 0.327 0.000
O42.9 Premature rupture of membranes, unspecified
0.672 0.328 0.000
Z93.9 Artificial opening status, unspecified
0.671 0.329 0.000
Z93.8 Other artificial opening status
0.671 0.329 0.000
Z93.0 Tracheostomy status
0.671 0.329 0.000
N41.0 Acute prostatitis
0.671 0.329 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.670 0.330 0.000
O36.8 Maternal care for other specified foetal problems
0.670 0.330 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.670 0.330 0.000
R27 Other lack of coordination
0.669 0.331 0.000
M46 Other inflammatory spondylopathies
0.668 0.332 0.000
Z83.5 Family history of eye and ear disorders
0.667 0.333 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.665 0.335 0.000
N62 Hypertrophy of breast
0.665 0.335 0.000
N81 Female genital prolapse
0.665 0.335 0.000
R87.6 Abnormal cytological findings
0.664 0.336 0.000
N61 Inflammatory disorders of breast
0.664 0.336 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.662 0.338 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.662 0.338 0.000
C15.8 Overlapping lesion of oesophagus
0.662 0.338 0.000
C15.4 Middle third of oesophagus
0.662 0.338 0.000
C15.3 Upper third of oesophagus
0.662 0.338 0.000
C15.2 Abdominal part of oesophagus
0.662 0.338 0.000
C15.1 Thoracic part of oesophagus
0.662 0.338 0.000
C15.0 Cervical part of oesophagus
0.662 0.338 0.000
Z47 Other orthopaedic follow-up care
0.662 0.338 0.000
Chapter I Certain infectious and parasitic diseases
0.662 0.338 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.661 0.338 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.661 0.338 0.000
M54.3 Sciatica
0.662 0.338 0.000
M84 Disorders of continuity of bone
0.661 0.339 0.000
D61 Other aplastic anaemias
0.660 0.340 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.660 0.340 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.660 0.340 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.660 0.340 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.660 0.340 0.000
M47.84 Other spondylosis (Thoracic region)
0.660 0.340 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.660 0.340 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.660 0.340 0.000
N03 Chronic nephritic syndrome
0.659 0.341 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.659 0.341 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.659 0.341 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.659 0.341 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.659 0.341 0.000
Z76 Persons encountering health services in other circumstances
0.659 0.341 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.659 0.341 0.000
R45 Symptoms and signs involving emotional state
0.659 0.341 0.000
H72.0 Central perforation of tympanic membrane
0.658 0.342 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.658 0.342 0.000
R23 Other skin changes
0.657 0.343 0.000
O36.9 Maternal care for foetal problem, unspecified
0.657 0.343 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.657 0.343 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.656 0.343 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.656 0.344 0.000
D18 Haemangioma and lymphangioma, any site
0.655 0.344 0.000
S20-S29 Injuries to the thorax
0.655 0.345 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.655 0.345 0.000
D62 Acute posthaemorrhagic anaemia
0.655 0.345 0.000
N50.9 Disorder of male genital organs, unspecified
0.654 0.346 0.000
N50.0 Atrophy of testis
0.654 0.346 0.000
N13.8 Other obstructive and reflux uropathy
0.654 0.346 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.654 0.346 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.654 0.346 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.653 0.347 0.000
O47 False labour
0.653 0.347 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.653 0.347 0.000
Z45.3 Adjustment and management of implanted hearing device
0.653 0.347 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.653 0.347 0.000
M45 Ankylosing spondylitis
0.653 0.347 0.000
R46 Symptoms and signs involving appearance and behaviour
0.653 0.347 0.000
C64-C68 Malignant neoplasms of urinary tract
0.652 0.348 0.000
M51 Other intervertebral disk disorders
0.652 0.348 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.651 0.349 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.651 0.349 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.651 0.349 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.650 0.349 0.000
R90.0 Intracranial space-occupying lesion
0.649 0.351 0.000
W00-W19 Falls
0.649 0.351 0.000
J22 Unspecified acute lower respiratory infection
0.649 0.351 0.000
N05 Unspecified nephritic syndrome
0.647 0.353 0.000
N25-N29 Other disorders of kidney and ureter
0.646 0.354 0.000
O66 Other obstructed labour
0.646 0.354 0.000
H80 Otosclerosis
0.646 0.354 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.646 0.354 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.645 0.355 0.000
H74 Other disorders of middle ear and mastoid
0.645 0.355 0.000
H70 Mastoiditis and related conditions
0.645 0.355 0.000
H69 Other disorders of Eustachian tube
0.645 0.355 0.000
H68 Eustachian salpingitis and obstruction
0.645 0.355 0.000
H67 Otitis media in diseases classified elsewhere
0.645 0.355 0.000
Z44.3 Fitting and adjustment of external breast prosthesis
0.645 0.355 0.000
F10.0 Acute intoxication
0.645 0.355 0.000
L90 Atrophic disorders of skin
0.645 0.355 0.000
S72.1 Pertrochanteric fracture
0.643 0.357 0.000
F80-F89 Disorders of psychological development
0.642 0.358 0.000
D75 Other diseases of blood and blood-forming organs
0.642 0.358 0.000
N04 Nephrotic syndrome
0.642 0.358 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.640 0.360 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.640 0.360 0.000
N94.5 Secondary dysmenorrhoea
0.640 0.360 0.000
N94.4 Primary dysmenorrhoea
0.640 0.360 0.000
N94.2 Vaginismus
0.640 0.360 0.000
N94.0 Mittelschmerz
0.640 0.360 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.640 0.360 0.000
K74 Fibrosis and cirrhosis of liver
0.640 0.360 0.000
R10 Abdominal and pelvic pain
0.639 0.361 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.639 0.361 0.000
N92.3 Ovulation bleeding
0.639 0.361 0.000
M10 Gout
0.638 0.362 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.637 0.363 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.637 0.363 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.637 0.363 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.637 0.363 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.637 0.363 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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