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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2507985
log Bayes Factor = 108.149
Chromosome 6   position 31,343,100  (GRCh37) Explore rs2507985 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E14.9 Without complications
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
M45 Ankylosing spondylitis
0.999 0.001 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.998 0.002 0.000
E10.1 With ketoacidosis
0.000 0.002 0.998
E11 Non-insulin-dependent diabetes mellitus
0.000 0.003 0.997
K51.4 Pseudopolyposis of colon
0.995 0.005 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.012 0.988
E20-E35 Disorders of other endocrine glands
0.000 0.016 0.984
E10.4 With neurological complications
0.000 0.019 0.981
K51.2 Ulcerative (chronic) proctitis
0.981 0.019 0.000
G35 Multiple sclerosis
0.980 0.020 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.021 0.979
E00-E07 Disorders of thyroid gland
0.000 0.022 0.978
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.022 0.978
E05.9 Thyrotoxicosis, unspecified
0.000 0.026 0.974
K51.3 Ulcerative (chronic) rectosigmoiditis
0.973 0.027 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.027 0.973
E11.1 With ketoacidosis
0.000 0.046 0.954
E27 Other disorders of adrenal gland
0.000 0.047 0.953
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.062 0.938
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.065 0.935
E10.0 With coma
0.000 0.068 0.932
E11.3 With ophthalmic complications
0.000 0.069 0.931
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.076 0.924
E11.0 With coma
0.000 0.085 0.915
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.090 0.910
E10.8 With unspecified complications
0.000 0.093 0.907
E27.1 Primary adrenocortical insufficiency
0.000 0.115 0.885
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.124 0.876
E14.1 With ketoacidosis
0.000 0.127 0.873
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.131 0.869
K51.8 Other ulcerative colitis
0.869 0.131 0.000
E10.6 With other specified complications
0.000 0.132 0.868
E11.9 Without complications
0.000 0.135 0.865
K51.5 Mucosal proctocolitis
0.863 0.137 0.000
E14.3 With ophthalmic complications
0.000 0.153 0.847
E23 Hypofunction and other disorders of pituitary gland
0.000 0.157 0.843
E22 Hyperfunction of pituitary gland
0.000 0.159 0.841
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.165 0.835
E11.5 With peripheral circulatory complications
0.000 0.170 0.830
E10.2 With renal complications
0.000 0.174 0.826
E14.6 With other specified complications
0.000 0.174 0.825
M45.X2 Ankylosing spondylitis (Cervical region)
0.825 0.175 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.185 0.815
E24 Cushing's syndrome
0.000 0.188 0.812
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.808 0.192 0.000
E13 Other specified diabetes mellitus
0.000 0.192 0.808
G35-G37 Demyelinating diseases of the central nervous system
0.803 0.197 0.000
E10.5 With peripheral circulatory complications
0.000 0.210 0.790
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.217 0.783
E16.1 Other hypoglycaemia
0.000 0.220 0.780
M45.X6 Ankylosing spondylitis (Lumbar region)
0.779 0.221 0.000
E05.8 Other thyrotoxicosis
0.000 0.223 0.777
E14.2 Withrenal complications
0.000 0.227 0.773
E23.2 Diabetes insipidus
0.000 0.233 0.767
E40-E46 Malnutrition
0.000 0.239 0.760
G37 Other demyelinating diseases of central nervous system
0.759 0.241 0.000
J45 Asthma
0.000 0.253 0.747
E07 Other disorders of thyroid
0.000 0.256 0.744
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.262 0.738
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.267 0.733
G37.9 Demyelinating disease of central nervous system, unspecified
0.726 0.274 0.000
E14.8 With unspecified complications
0.000 0.277 0.722
E28 Ovarian dysfunction
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.716 0.284 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.716 0.284 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.716 0.284 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.716 0.284 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.716 0.284 0.000
E11.7 With multiple complications
0.000 0.285 0.715
E25 Adrenogenital disorders
0.000 0.290 0.710
E34 Other endocrine disorders
0.000 0.292 0.708
E24.0 Pituitary-dependent Cushing's disease
0.000 0.292 0.708
E10.7 With multiple complications
0.000 0.293 0.706
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.294 0.706
E32 Diseases of thymus
0.000 0.294 0.706
E30 Disorders of puberty, not elsewhere classified
0.000 0.294 0.706
M06 Other rheumatoid arthritis
0.010 0.296 0.694
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.297 0.703
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.299 0.701
E00 Congenital iodine-deficiency syndrome
0.000 0.299 0.701
E05.5 Thyroid crisis or storm
0.000 0.299 0.701
E05.4 Thyrotoxicosis factitia
0.000 0.299 0.701
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.299 0.701
E14.5 With peripheral circulatory complications
0.000 0.302 0.698
E22.0 Acromegaly and pituitary gigantism
0.000 0.305 0.695
K51.0 Ulcerative (chronic) enterocolitis
0.693 0.307 0.000
E29 Testicular dysfunction
0.000 0.312 0.688
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.312 0.687
E31 Polyglandular dysfunction
0.000 0.314 0.686
E27.5 Adrenomedullary hyperfunction
0.000 0.317 0.683
E27.0 Other adrenocortical overactivity
0.000 0.317 0.683
E13.9 Without complications
0.000 0.320 0.680
M06.3 Rheumatoid nodule
0.002 0.320 0.677
E20 Hypoparathyroidism
0.000 0.326 0.674
E23.7 Disorder of pituitary gland, unspecified
0.000 0.331 0.669
E11.4 With neurological complications
0.000 0.336 0.664
E26 Hyperaldosteronism
0.000 0.338 0.661
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.350 0.650
E14.4 With neurological complications
0.000 0.351 0.649
E11.8 With unspecified complications
0.000 0.353 0.647
K90 Intestinal malabsorption
0.000 0.353 0.647
M06.34 Rheumatoid nodule (Hand)
0.001 0.362 0.638
E27.8 Other specified disorders of adrenal gland
0.000 0.367 0.632
E11.6 With other specified complications
0.000 0.368 0.632
J45.0 Predominantly allergic asthma
0.000 0.371 0.629
J45.1 Nonallergic asthma
0.000 0.383 0.617
G36 Other acute disseminated demyelination
0.615 0.385 0.000
E07.8 Other specified disorders of thyroid
0.000 0.388 0.612
K51.1 Ulcerative (chronic) ileocolitis
0.609 0.391 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.396 0.604
E23.1 Drug-induced hypopituitarism
0.000 0.396 0.604
E24.2 Drug-induced Cushing's syndrome
0.000 0.396 0.604
E22.8 Other hyperfunction of pituitary gland
0.000 0.397 0.603
E28.2 Polycystic ovarian syndrome
0.000 0.402 0.598
E11.2 With renal complications
0.000 0.403 0.596
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.405 0.595
E23.6 Other disorders of pituitary gland
0.000 0.406 0.593
M06.32 Rheumatoid nodule (Upper arm)
0.001 0.407 0.592
J45.8 Mixed asthma
0.000 0.407 0.593
E46 Unspecified protein-energy malnutrition
0.000 0.411 0.589
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.416 0.584
E22.1 Hyperprolactinaemia
0.000 0.417 0.583
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.418 0.582
E24.3 Ectopic ACTH syndrome
0.000 0.418 0.582
E24.1 Nelson's syndrome
0.000 0.418 0.582
E13.8 With unspecified complications
0.000 0.421 0.579
E13.7 With multiple complications
0.000 0.421 0.579
E13.6 With other specified complications
0.000 0.421 0.579
E13.5 With peripheral circulatory complications
0.000 0.421 0.579
E13.4 With neurological complications
0.000 0.421 0.579
E13.2 With renal complications
0.000 0.421 0.579
E13.1 With ketoacidosis
0.000 0.421 0.579
E13.0 With coma
0.000 0.421 0.579
G37.8 Other specified demyelinating diseases of central nervous system
0.577 0.423 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.425 0.575
E13.3 With ophthalmic complications
0.000 0.439 0.561
E24.9 Cushing's syndrome, unspecified
0.000 0.439 0.561
K90.9 Intestinal malabsorption, unspecified
0.000 0.448 0.552
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.455 0.545
E45 Retarded development following protein-energy malnutrition
0.000 0.455 0.545
E43 Unspecified severe protein-energy malnutrition
0.000 0.455 0.545
E42 Marasmic kwashiorkor
0.000 0.455 0.545
E41 Nutritional marasmus
0.000 0.455 0.545
E40 Kwashiorkor
0.000 0.455 0.545
G37.5 Concentric sclerosis [Balo]
0.545 0.455 0.000
G37.4 Subacute necrotising myelitis
0.545 0.455 0.000
G37.2 Central pontine myelinolysis
0.545 0.455 0.000
G37.1 Central demyelination of corpus callosum
0.545 0.455 0.000
G37.0 Diffuse sclerosis
0.545 0.455 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.460 0.540
E27.2 Addisonian crisis
0.000 0.462 0.538
E24.8 Other Cushing's syndrome
0.000 0.462 0.537
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.463 0.537
M06.37 Rheumatoid nodule (Ankle and foot)
0.001 0.464 0.535
E34.9 Endocrine disorder, unspecified
0.000 0.466 0.534
E07.1 Dyshormogenetic goitre
0.000 0.467 0.533
E07.0 Hypersecretion of calcitonin
0.000 0.467 0.533
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.525 0.475 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.485 0.514
E28.9 Ovarian dysfunction, unspecified
0.000 0.485 0.514
E28.8 Other ovarian dysfunction
0.000 0.485 0.514
E28.1 Androgen excess
0.000 0.485 0.514
E28.0 Oestrogen excess
0.000 0.485 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.486 0.514
M06.8 Other specified rheumatoid arthritis
0.007 0.487 0.506
E25.9 Adrenogenital disorder, unspecified
0.000 0.490 0.509
E25.8 Other adrenogenital disorders
0.000 0.490 0.509
K90.8 Other intestinal malabsorption
0.000 0.492 0.508
E34.0 Carcinoid syndrome
0.000 0.492 0.508
E34.5 Androgen resistance syndrome
0.000 0.492 0.507
E34.4 Constitutional tall stature
0.000 0.492 0.507
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.492 0.507
E34.1 Other hypersecretion of intestinal hormones
0.000 0.492 0.507
E30.9 Disorder of puberty, unspecified
0.000 0.494 0.506
E30.8 Other disorders of puberty
0.000 0.494 0.506
E30.1 Precocious puberty
0.000 0.494 0.506
E30.0 Delayed puberty
0.000 0.494 0.506
E32.9 Disease of thymus, unspecified
0.000 0.494 0.506
E32.8 Other diseases of thymus
0.000 0.494 0.506
E32.1 Abscess of thymus
0.000 0.494 0.506
E32.0 Persistent hyperplasia of thymus
0.000 0.494 0.506
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.494 0.506
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.494 0.506
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.494 0.506
M06.2 Rheumatoid bursitis
0.008 0.495 0.498
M06.1 Adult-onset Still's disease
0.008 0.495 0.498
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.497 0.503
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.497 0.503
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.497 0.503
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.497 0.503
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.497 0.503
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.497 0.503
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.497 0.503
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.497 0.503
M06.30 Rheumatoid nodule (Multiple sites)
0.002 0.501 0.497
E34.8 Other specified endocrine disorders
0.000 0.504 0.496
E29.9 Testicular dysfunction, unspecified
0.000 0.507 0.493
E29.8 Other testicular dysfunction
0.000 0.507 0.493
E29.0 Testicular hyperfunction
0.000 0.507 0.493
E31.9 Polyglandular dysfunction, unspecified
0.000 0.508 0.492
E31.8 Other polyglandular dysfunction
0.000 0.508 0.492
E31.1 Polyglandular hyperfunction
0.000 0.508 0.492
E34.3 Short stature, not elsewhere classified
0.000 0.509 0.491
M06.39 Rheumatoid nodule (Site unspecified)
0.002 0.513 0.486
M06.38 Rheumatoid nodule (Other)
0.002 0.513 0.486
M06.36 Rheumatoid nodule (Lower leg)
0.002 0.513 0.486
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.002 0.513 0.486
M06.33 Rheumatoid nodule (Forearm)
0.002 0.513 0.486
M06.31 Rheumatoid nodule (Shoulder region)
0.002 0.513 0.486
E20.8 Other hypoparathyroidism
0.000 0.517 0.483
E20.1 Pseudohypoparathyroidism
0.000 0.517 0.483
E20.0 Idiopathic hypoparathyroidism
0.000 0.517 0.483
G36.0 Neuromyelitis optica [Devic]
0.480 0.519 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.524 0.476
E29.1 Testicular hypofunction
0.000 0.525 0.475
E26.8 Other hyperaldosteronism
0.000 0.525 0.474
E26.1 Secondary hyperaldosteronism
0.000 0.525 0.474
E31.0 Autoimmune polyglandular failure
0.000 0.528 0.472
K90.3 Pancreatic steatorrhoea
0.000 0.536 0.464
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.536 0.464
K90.1 Tropical sprue
0.000 0.536 0.464
E06 Thyroiditis
0.000 0.540 0.459
E20.9 Hypoparathyroidism, unspecified
0.000 0.549 0.451
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.556 0.444
G36.9 Acute disseminated demyelination, unspecified
0.441 0.559 0.000
G36.8 Other specified acute disseminated demyelination
0.441 0.559 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.441 0.559 0.000
M06.4 Inflammatory polyarthropathy
0.007 0.565 0.429
E03 Other hypothyroidism
0.000 0.576 0.424
E23.0 Hypopituitarism
0.000 0.581 0.419
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.595 0.405
E28.3 Primary ovarian failure
0.000 0.609 0.391
E44.1 Mild protein-energy malnutrition
0.000 0.609 0.391
E44.0 Moderate protein-energy malnutrition
0.000 0.609 0.391
E21.4 Other specified disorders of parathyroid gland
0.000 0.615 0.385
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.005 0.624 0.371
E21.0 Primary hyperparathyroidism
0.000 0.626 0.374
M06.88 Other specified rheumatoid arthritis (Other)
0.005 0.632 0.363
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.005 0.632 0.363
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.005 0.632 0.363
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.005 0.632 0.363
M06.84 Other specified rheumatoid arthritis (Hand)
0.005 0.632 0.363
M06.83 Other specified rheumatoid arthritis (Forearm)
0.005 0.632 0.363
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.005 0.632 0.363
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.005 0.632 0.363
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.005 0.632 0.363
E26.0 Primary hyperaldosteronism
0.000 0.633 0.367
M06.19 Adult-onset Still's disease (Site unspecified)
0.006 0.638 0.357
M06.18 Adult-onset Still's disease (Other)
0.006 0.638 0.357
M06.17 Adult-onset Still's disease (Ankle and foot)
0.006 0.638 0.357
M06.16 Adult-onset Still's disease (Lower leg)
0.006 0.638 0.357
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.006 0.638 0.357
M06.14 Adult-onset Still's disease (Hand)
0.006 0.638 0.357
M06.13 Adult-onset Still's disease (Forearm)
0.006 0.638 0.357
M06.12 Adult-onset Still's disease (Upper arm)
0.006 0.638 0.357
M06.11 Adult-onset Still's disease (Shoulder region)
0.006 0.638 0.357
M06.10 Adult-onset Still's disease (Multiple sites)
0.006 0.638 0.357
M06.29 Rheumatoid bursitis (Site unspecified)
0.006 0.638 0.357
M06.28 Rheumatoid bursitis (Other)
0.006 0.638 0.357
M06.27 Rheumatoid bursitis (Ankle and foot)
0.006 0.638 0.357
M06.26 Rheumatoid bursitis (Lower leg)
0.006 0.638 0.357
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.006 0.638 0.357
M06.24 Rheumatoid bursitis (Hand)
0.006 0.638 0.357
M06.23 Rheumatoid bursitis (Forearm)
0.006 0.638 0.357
M06.22 Rheumatoid bursitis (Upper arm)
0.006 0.638 0.357
M06.21 Rheumatoid bursitis (Shoulder region)
0.006 0.638 0.357
M06.20 Rheumatoid bursitis (Multiple sites)
0.006 0.638 0.357
E65-E68 Obesity and other hyperalimentation
0.000 0.647 0.353
H20.9 Iridocyclitis, unspecified
0.343 0.657 0.000
E21.2 Other hyperparathyroidism
0.000 0.658 0.341
E21.3 Hyperparathyroidism, unspecified
0.000 0.659 0.341
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.670 0.330
E06.4 Drug-induced thyroiditis
0.000 0.670 0.329
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.670 0.329
E06.0 Acute thyroiditis
0.000 0.670 0.329
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.671 0.329
E06.1 Subacute thyroiditis
0.000 0.671 0.328
E06.5 Other chronic thyroiditis
0.000 0.685 0.315
M06.48 Inflammatory polyarthropathy (Other)
0.005 0.688 0.307
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.005 0.688 0.307
M06.46 Inflammatory polyarthropathy (Lower leg)
0.005 0.688 0.307
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.005 0.688 0.307
M06.44 Inflammatory polyarthropathy (Hand)
0.005 0.688 0.307
M06.43 Inflammatory polyarthropathy (Forearm)
0.005 0.688 0.307
M06.42 Inflammatory polyarthropathy (Upper arm)
0.005 0.688 0.307
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.005 0.688 0.307
K50-K52 Noninfective enteritis and colitis
0.306 0.694 0.000
E03.5 Myxoedema coma
0.000 0.696 0.304
E03.4 Atrophy of thyroid (acquired)
0.000 0.696 0.304
E03.3 Postinfectious hypothyroidism
0.000 0.696 0.304
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.696 0.304
H20 Iridocyclitis
0.301 0.699 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.005 0.702 0.293
E03.1 Congenital hypothyroidism without goitre
0.000 0.710 0.290
E03.8 Other specified hypothyroidism
0.000 0.712 0.288
E50-E64 Other nutritional deficiencies
0.000 0.719 0.281
H20.0 Acute and subacute iridocyclitis
0.264 0.736 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.005 0.737 0.258
E06.3 Autoimmune thyroiditis
0.000 0.738 0.261
H20.1 Chronic iridocyclitis
0.256 0.744 0.000
E67 Other hyperalimentation
0.000 0.746 0.253
E68 Sequelae of hyperalimentation
0.000 0.746 0.253
H20.8 Other iridocyclitis
0.245 0.755 0.000
E06.9 Thyroiditis, unspecified
0.000 0.758 0.242
K50 Crohn's disease [regional enteritis]
0.221 0.779 0.000
E83 Disorders of mineral metabolism
0.218 0.781 0.001
H20.2 Lens-induced iridocyclitis
0.216 0.784 0.000
E51 Thiamine deficiency
0.000 0.786 0.214
E58 Dietary calcium deficiency
0.000 0.796 0.204
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.798 0.202
E63 Other nutritional deficiencies
0.000 0.798 0.202
E50 Vitamin A deficiency
0.000 0.798 0.202
E60 Dietary zinc deficiency
0.000 0.798 0.202
E59 Dietary selenium deficiency
0.000 0.798 0.202
E54 Ascorbic acid deficiency
0.000 0.798 0.202
E52 Niacin deficiency [pellagra]
0.000 0.798 0.202
E65 Localised adiposity
0.000 0.803 0.197
K50.9 Crohn's disease, unspecified
0.195 0.805 0.000
E67.8 Other specified hyperalimentation
0.000 0.818 0.182
E67.3 Hypervitaminosis D
0.000 0.818 0.182
E67.2 Megavitamin-B6 syndrome
0.000 0.818 0.182
E67.1 Hypercarotenaemia
0.000 0.818 0.182
E67.0 Hypervitaminosis A
0.000 0.818 0.182
H36.0 Diabetic retinopathy
0.000 0.819 0.181
E56 Other vitamin deficiencies
0.000 0.820 0.180
K50.1 Crohn's disease of large intestine
0.180 0.820 0.000
M07.3 Other psoriatic arthropathies
0.173 0.827 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.170 0.830 0.000
E51.2 Wernicke's encephalopathy
0.000 0.834 0.166
M07.39 Other psoriatic arthropathies (Site unspecified)
0.161 0.838 0.000
K52 Other non-infective gastro-enteritis and colitis
0.161 0.839 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.157 0.842 0.001
E83.8 Other disorders of mineral metabolism
0.157 0.842 0.001
E83.2 Disorders of zinc metabolism
0.157 0.842 0.001
E83.0 Disorders of copper metabolism
0.157 0.842 0.001
E51.9 Thiamine deficiency, unspecified
0.000 0.846 0.153
E51.8 Other manifestations of thiamine deficiency
0.000 0.846 0.153
E51.1 Beriberi
0.000 0.846 0.153
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.149 0.851 0.000
E55 Vitamin D deficiency
0.000 0.851 0.149
K52.3 Indeterminate colitis
0.148 0.852 0.000
E61 Deficiency of other nutrient elements
0.000 0.854 0.146
E50.9 Vitamin A deficiency, unspecified
0.000 0.855 0.145
E50.8 Other manifestations of vitamin A deficiency
0.000 0.855 0.145
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.855 0.145
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.855 0.145
E50.5 Vitamin A deficiency with night blindness
0.000 0.855 0.145
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.855 0.145
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.855 0.145
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.855 0.145
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.855 0.145
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.855 0.145
E63.9 Nutritional deficiency, unspecified
0.000 0.855 0.145
E63.8 Other specified nutritional deficiencies
0.000 0.855 0.145
E63.1 Imbalance of constituents of food intake
0.000 0.855 0.145
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.855 0.145
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.855 0.145
E64.8 Sequelae of other nutritional deficiencies
0.000 0.855 0.145
E64.3 Sequelae of rickets
0.000 0.855 0.145
E64.2 Sequelae of vitamin C deficiency
0.000 0.855 0.145
E64.1 Sequelae of vitamin A deficiency
0.000 0.855 0.145
E64.0 Sequelae of protein-energy malnutrition
0.000 0.855 0.145
M45-M49 Spondylopathies
0.144 0.856 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.143 0.857 0.000
E83.3 Disorders of phosphorus metabolism
0.142 0.857 0.001
M07.34 Other psoriatic arthropathies (Hand)
0.140 0.859 0.000
M06.0 Seronegative rheumatoid arthritis
0.009 0.861 0.129
M07.36 Other psoriatic arthropathies (Lower leg)
0.135 0.865 0.000
M07 Psoriatic and enteropathic arthropathies
0.122 0.865 0.013
M07.31 Other psoriatic arthropathies (Shoulder region)
0.134 0.866 0.000
M07.38 Other psoriatic arthropathies (Other)
0.133 0.867 0.000
E83.4 Disorders of magnesium metabolism
0.133 0.867 0.000
K52.1 Toxic gastro-enteritis and colitis
0.132 0.868 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.871 0.129
E56.8 Deficiency of other vitamins
0.000 0.871 0.129
E56.0 Deficiency of vitamin E
0.000 0.871 0.129
K52.0 Gastro-enteritis and colitis due to radiation
0.125 0.875 0.000
K50.0 Crohn's disease of small intestine
0.125 0.875 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.124 0.876 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.124 0.876 0.000
E83.5 Disorders of calcium metabolism
0.122 0.878 0.000
M05-M14 Inflammatory polyarthropathies
0.085 0.884 0.031
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.111 0.889 0.000
E04 Other non-toxic goitre
0.000 0.890 0.110
H36 Retinal disorders in diseases classified elsewhere
0.000 0.891 0.109
E56.1 Deficiency of vitamin K
0.001 0.892 0.107
E55.0 Rickets, active
0.000 0.893 0.107
E53 Deficiency of other B group vitamins
0.000 0.893 0.107
E61.9 Deficiency of nutrient element, unspecified
0.000 0.895 0.105
E61.8 Deficiency of other specified nutrient elements
0.000 0.895 0.105
E61.7 Deficiency of multiple nutrient elements
0.000 0.895 0.105
E61.6 Vanadium deficiency
0.000 0.895 0.105
E61.5 Molybdenum deficiency
0.000 0.895 0.105
E61.4 Chromium deficiency
0.000 0.895 0.105
E61.3 Manganese deficiency
0.000 0.895 0.105
E61.0 Copper deficiency
0.000 0.895 0.105
H21 Other disorders of iris and ciliary body
0.104 0.896 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.104 0.896 0.000
M48 Other spondylopathies
0.101 0.899 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.007 0.900 0.093
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.007 0.900 0.093
M06.04 Seronegative rheumatoid arthritis (Hand)
0.007 0.900 0.093
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.007 0.900 0.093
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.007 0.900 0.093
I10 Essential (primary) hypertension
0.000 0.901 0.099
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.098 0.902 0.000
M07.6 Other enteropathic arthropathies
0.089 0.902 0.009
M07.5 Arthropathy in ulcerative colitis
0.088 0.903 0.009
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.088 0.903 0.009
M07.2 Psoriatic spondylitis
0.088 0.903 0.009
M07.1 Arthritis mutilans
0.088 0.903 0.009
M07.0 Distal interphalangeal psoriatic arthropathy
0.088 0.903 0.009
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.007 0.908 0.084
K75.4 Autoimmune hepatitis
0.000 0.908 0.092
M48.5 Collapsed vertebra, not elsewhere classified
0.090 0.910 0.000
M00-M03 Infectious arthropathies
0.089 0.911 0.000
M00 Pyogenic arthritis
0.088 0.912 0.000
E61.1 Iron deficiency
0.000 0.912 0.088
M49 Spondylopathies in diseases classified elsewhere
0.088 0.912 0.000
M00.9 Pyogenic arthritis, unspecified
0.086 0.914 0.000
K75 Other inflammatory liver diseases
0.000 0.914 0.086
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.085 0.915 0.000
M02 Reactive arthropathies
0.085 0.915 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.085 0.915 0.000
M08 Juvenile arthritis
0.063 0.916 0.022
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.008 0.916 0.077
I83 Varicose veins of lower extremities
0.084 0.916 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.061 0.916 0.023
H21.8 Other specified disorders of iris and ciliary body
0.083 0.917 0.000
K70-K77 Diseases of liver
0.000 0.917 0.083
K50.8 Other Crohn's disease
0.083 0.917 0.000
K74 Fibrosis and cirrhosis of liver
0.000 0.917 0.083
M12 Other specific arthropathies
0.062 0.918 0.021
M05 Seropositive rheumatoid arthritis
0.055 0.918 0.027
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.082 0.918 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.081 0.919 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.080 0.920 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.920 0.080
M11 Other crystal arthropathies
0.064 0.920 0.016
E04.8 Other specified non-toxic goitre
0.000 0.921 0.079
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.921 0.078
I83.1 Varicose veins of lower extremities with inflammation
0.078 0.922 0.000
K72.9 Hepatic failure, unspecified
0.000 0.922 0.078
M02.3 Reiter's disease
0.077 0.923 0.000
E53.1 Pyridoxine deficiency
0.000 0.923 0.077
E53.0 Riboflavin deficiency
0.000 0.923 0.077
E61.2 Magnesium deficiency
0.001 0.923 0.076
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.076 0.924 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.076 0.924 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.076 0.924 0.000
M48.9 Spondylopathy, unspecified
0.076 0.924 0.000
H21.2 Degeneration of iris and ciliary body
0.076 0.924 0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)
0.076 0.924 0.000
M02.9 Reactive arthopathy, unspecified
0.076 0.924 0.000
K74.6 Other and unspecified cirrhosis of liver
0.000 0.924 0.076
M00.0 Staphylococcal arthritis and polyarthritis
0.076 0.924 0.000
M14 Arthropathies in other diseases classified elsewhere
0.054 0.925 0.022
K73 Chronic hepatitis, not elsewhere classified
0.000 0.925 0.075
H21.4 Pupillary membranes
0.075 0.925 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.075 0.925 0.000
K74.3 Primary biliary cirrhosis
0.000 0.925 0.075
K75.8 Other specified inflammatory liver diseases
0.000 0.925 0.075
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.073 0.926 0.000
M48.4 Fatigue fracture of vertebra
0.072 0.928 0.000
M48.3 Traumatic spondylopathy
0.072 0.928 0.000
M48.2 Kissing spine
0.072 0.928 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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