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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2516448
log Bayes Factor = 89.2843
Chromosome 6   position 31,390,410  (GRCh37) Explore rs2516448 on Ensembl!
Variant rs2516448 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
R31 Unspecified haematuria
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E27 Other disorders of adrenal gland
0.000 0.003 0.997
E10.9 Without complications
0.000 0.005 0.995
E10 Insulin-dependent diabetes mellitus
0.000 0.006 0.994
E20-E35 Disorders of other endocrine glands
0.000 0.006 0.994
E10-E14 Diabetes mellitus
0.000 0.006 0.994
I77.1 Stricture of artery
0.000 0.010 0.990
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.012 0.988
I77 Other disorders of arteries and arterioles
0.000 0.014 0.986
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.022 0.978
I73 Other peripheral vascular diseases
0.000 0.027 0.973
I73.0 Raynaud's syndrome
0.000 0.040 0.960
L40.0 Psoriasis vulgaris
0.950 0.050 0.000
E10.1 With ketoacidosis
0.000 0.052 0.948
M45 Ankylosing spondylitis
0.935 0.065 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.919 0.081 0.000
E27.2 Addisonian crisis
0.000 0.092 0.908
I77.6 Arteritis, unspecified
0.000 0.100 0.900
I73.9 Peripheral vascular disease, unspecified
0.000 0.104 0.896
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.104 0.896
L40.4 Guttate psoriasis
0.861 0.139 0.000
I74 Arterial embolism and thrombosis
0.000 0.150 0.850
I72 Other aneurysm
0.000 0.162 0.838
L40.8 Other psoriasis
0.831 0.169 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.176 0.824
K90 Intestinal malabsorption
0.000 0.189 0.811
E20 Hypoparathyroidism
0.000 0.192 0.808
I71 Aortic aneurysm and dissection
0.000 0.198 0.802
I77.8 Other specified disorders of arteries and arterioles
0.000 0.203 0.797
D69.6 Thrombocytopenia, unspecified
0.000 0.213 0.787
D69 Purpura and other haemorrhagic conditions
0.000 0.215 0.785
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.217 0.783
E07 Other disorders of thyroid
0.000 0.217 0.783
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.220 0.780
I74.8 Embolism and thrombosis of other arteries
0.000 0.229 0.771
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.231 0.768
E28 Ovarian dysfunction
0.000 0.242 0.758
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.244 0.756
E10.0 With coma
0.000 0.245 0.755
K90.9 Intestinal malabsorption, unspecified
0.000 0.246 0.754
E10.2 With renal complications
0.000 0.248 0.752
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.248 0.752
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.250 0.750
I72.8 Aneurysm of other specified arteries
0.000 0.257 0.743
L40.1 Generalised pustular psoriasis
0.737 0.262 0.000
E50-E64 Other nutritional deficiencies
0.000 0.263 0.737
E06 Thyroiditis
0.000 0.263 0.736
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.270 0.730
I77.2 Rupture of artery
0.000 0.270 0.730
E10.3 With ophthalmic complications
0.000 0.271 0.729
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.274 0.726
E07.8 Other specified disorders of thyroid
0.000 0.276 0.724
I72.3 Aneurysm of iliac artery
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.282 0.718
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E27.5 Adrenomedullary hyperfunction
0.000 0.285 0.715
E27.0 Other adrenocortical overactivity
0.000 0.285 0.715
D69.5 Secondary thrombocytopenia
0.000 0.287 0.713
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.287 0.712
E32 Diseases of thymus
0.000 0.287 0.712
E31 Polyglandular dysfunction
0.000 0.287 0.712
E30 Disorders of puberty, not elsewhere classified
0.000 0.287 0.712
E12 Malnutrition-related diabetes mellitus
0.000 0.288 0.712
E10.6 With other specified complications
0.000 0.288 0.712
L40.3 Pustulosis palmaris et plantaris
0.710 0.290 0.000
I77.5 Necrosis of artery
0.000 0.293 0.707
I77.4 Coeliac artery compression syndrome
0.000 0.293 0.707
I77.3 Arterial fibromuscular dysplasia
0.000 0.293 0.707
E03.8 Other specified hypothyroidism
0.000 0.297 0.703
E53 Deficiency of other B group vitamins
0.000 0.298 0.702
E25 Adrenogenital disorders
0.000 0.302 0.698
E34 Other endocrine disorders
0.000 0.310 0.690
M45.X6 Ankylosing spondylitis (Lumbar region)
0.685 0.314 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.325 0.675
E53.8 Deficiency of other specified B group vitamins
0.000 0.327 0.673
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.670 0.330 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.670 0.330 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.670 0.330 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.670 0.330 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.670 0.330 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.670 0.330 0.000
E28.3 Primary ovarian failure
0.000 0.331 0.669
E03.1 Congenital hypothyroidism without goitre
0.000 0.332 0.667
I71.0 Dissection of aorta [any part]
0.000 0.332 0.667
M45.X2 Ankylosing spondylitis (Cervical region)
0.665 0.335 0.000
E06.3 Autoimmune thyroiditis
0.000 0.335 0.664
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.337 0.663
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.341 0.659
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.344 0.656
E40-E46 Malnutrition
0.000 0.348 0.652
L40-L45 Papulosquamous disorders
0.644 0.356 0.000
D69.4 Other primary thrombocytopenia
0.000 0.374 0.626
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.380 0.620
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.380 0.620
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.381 0.619
I72.4 Aneurysm of artery of lower extremity
0.000 0.384 0.616
I73.8 Other specified peripheral vascular diseases
0.000 0.386 0.614
I72.9 Aneurysm of unspecified site
0.000 0.387 0.613
E22 Hyperfunction of pituitary gland
0.000 0.387 0.613
D69.2 Other nonthrombocytopenic purpura
0.000 0.391 0.609
E05.8 Other thyrotoxicosis
0.000 0.391 0.608
E10.8 With unspecified complications
0.000 0.392 0.608
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.393 0.606
E10.5 With peripheral circulatory complications
0.000 0.394 0.606
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.399 0.601
I79.1 Aortitis in diseases classified elsewhere
0.000 0.409 0.591
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.409 0.591
I72.2 Aneurysm of renal artery
0.000 0.415 0.585
K90.3 Pancreatic steatorrhoea
0.000 0.418 0.582
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.418 0.582
K90.1 Tropical sprue
0.000 0.418 0.582
D69.0 Allergic purpura
0.000 0.419 0.581
E34.8 Other specified endocrine disorders
0.000 0.419 0.581
E20.8 Other hypoparathyroidism
0.000 0.421 0.579
E20.1 Pseudohypoparathyroidism
0.000 0.421 0.579
E20.0 Idiopathic hypoparathyroidism
0.000 0.421 0.579
I77.0 Arteriovenous fistula, acquired
0.000 0.421 0.579
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.425 0.575
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.425 0.575
E16 Other disorders of pancreatic internal secretion
0.000 0.427 0.573
I74.5 Embolism and thrombosis of iliac artery
0.000 0.428 0.572
E13 Other specified diabetes mellitus
0.000 0.428 0.572
K90.8 Other intestinal malabsorption
0.000 0.432 0.568
E27.9 Disorder of adrenal gland, unspecified
0.000 0.432 0.568
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.435 0.565
I72.1 Aneurysm of artery of upper extremity
0.000 0.436 0.564
D69.8 Other specified haemorrhagic conditions
0.000 0.437 0.563
E27.8 Other specified disorders of adrenal gland
0.000 0.437 0.563
E29 Testicular dysfunction
0.000 0.438 0.562
E07.1 Dyshormogenetic goitre
0.000 0.438 0.562
E07.0 Hypersecretion of calcitonin
0.000 0.438 0.562
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.449 0.551
E23 Hypofunction and other disorders of pituitary gland
0.000 0.451 0.549
E28.9 Ovarian dysfunction, unspecified
0.000 0.457 0.543
E28.8 Other ovarian dysfunction
0.000 0.457 0.543
E28.1 Androgen excess
0.000 0.457 0.543
E28.0 Oestrogen excess
0.000 0.457 0.543
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.459 0.540
E15 Nondiabetic hypoglycaemic coma
0.000 0.462 0.538
E34.9 Endocrine disorder, unspecified
0.000 0.465 0.535
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.467 0.532
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.471 0.528
E63 Other nutritional deficiencies
0.000 0.471 0.528
E50 Vitamin A deficiency
0.000 0.471 0.528
E60 Dietary zinc deficiency
0.000 0.471 0.528
E59 Dietary selenium deficiency
0.000 0.471 0.528
E52 Niacin deficiency [pellagra]
0.000 0.471 0.528
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.472 0.528
E53.9 Vitamin B deficiency, unspecified
0.000 0.472 0.528
E06.4 Drug-induced thyroiditis
0.000 0.472 0.528
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.472 0.528
E06.0 Acute thyroiditis
0.000 0.472 0.528
D69.1 Qualitative platelet defects
0.000 0.475 0.524
L43 Lichen planus
0.521 0.479 0.000
E14 Unspecified diabetes mellitus
0.000 0.481 0.519
E10.4 With neurological complications
0.000 0.482 0.518
D69.9 Haemorrhagic condition, unspecified
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E51 Thiamine deficiency
0.000 0.486 0.514
L42 Pityriasis rosea
0.513 0.486 0.000
L41 Parapsoriasis
0.513 0.487 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.489 0.511
E30.8 Other disorders of puberty
0.000 0.489 0.511
E30.1 Precocious puberty
0.000 0.489 0.511
E30.0 Delayed puberty
0.000 0.489 0.511
E31.9 Polyglandular dysfunction, unspecified
0.000 0.489 0.511
E31.8 Other polyglandular dysfunction
0.000 0.489 0.511
E31.1 Polyglandular hyperfunction
0.000 0.489 0.511
E31.0 Autoimmune polyglandular failure
0.000 0.489 0.511
E32.9 Disease of thymus, unspecified
0.000 0.489 0.511
E32.8 Other diseases of thymus
0.000 0.489 0.511
E32.1 Abscess of thymus
0.000 0.489 0.511
E32.0 Persistent hyperplasia of thymus
0.000 0.489 0.511
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.489 0.511
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.489 0.511
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.489 0.511
E12.9 Without complications
0.000 0.489 0.511
E12.8 With unspecified complications
0.000 0.489 0.511
E12.7 With multiple complications
0.000 0.489 0.511
E12.6 With other specified complications
0.000 0.489 0.511
E12.5 With peripheral circulatory complications
0.000 0.489 0.511
E12.4 With neurological complications
0.000 0.489 0.511
E12.3 With ophthalmic complications
0.000 0.489 0.511
E12.2 With renal complications
0.000 0.489 0.511
E12.1 With ketoacidosis
0.000 0.489 0.511
E12.0 With coma
0.000 0.489 0.511
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.492 0.508
I70 Atherosclerosis
0.000 0.495 0.505
E53.1 Pyridoxine deficiency
0.000 0.497 0.503
E53.0 Riboflavin deficiency
0.000 0.497 0.503
E56 Other vitamin deficiencies
0.000 0.499 0.501
E25.9 Adrenogenital disorder, unspecified
0.000 0.499 0.500
E25.8 Other adrenogenital disorders
0.000 0.499 0.500
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.504 0.496
E34.5 Androgen resistance syndrome
0.000 0.505 0.494
E34.4 Constitutional tall stature
0.000 0.505 0.494
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.505 0.494
E34.1 Other hypersecretion of intestinal hormones
0.000 0.505 0.494
E54 Ascorbic acid deficiency
0.000 0.507 0.493
E06.5 Other chronic thyroiditis
0.000 0.511 0.489
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.511 0.489
E23.2 Diabetes insipidus
0.000 0.513 0.487
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.514 0.486
J84 Other interstitial pulmonary diseases
0.000 0.519 0.481
E16.2 Hypoglycaemia, unspecified
0.000 0.520 0.480
I72.0 Aneurysm of carotid artery
0.000 0.523 0.477
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.525 0.475
E26 Hyperaldosteronism
0.001 0.529 0.470
E06.9 Thyroiditis, unspecified
0.000 0.532 0.468
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.532 0.468
E45 Retarded development following protein-energy malnutrition
0.000 0.532 0.468
E43 Unspecified severe protein-energy malnutrition
0.000 0.532 0.468
E42 Marasmic kwashiorkor
0.000 0.532 0.468
E41 Nutritional marasmus
0.000 0.532 0.468
E40 Kwashiorkor
0.000 0.532 0.468
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.534 0.466
E34.3 Short stature, not elsewhere classified
0.000 0.538 0.462
L45 Papulosquamous disorders in diseases classified elsewhere
0.461 0.538 0.000
E58 Dietary calcium deficiency
0.000 0.558 0.442
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.560 0.439
E22.8 Other hyperfunction of pituitary gland
0.000 0.560 0.439
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.561 0.439
J33.0 Polyp of nasal cavity
0.000 0.564 0.436
L44 Other papulosquamous disorders
0.434 0.566 0.000
E22.1 Hyperprolactinaemia
0.000 0.568 0.432
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.572 0.427
J84.8 Other specified interstitial pulmonary diseases
0.000 0.577 0.423
L41.1 Pityriasis lichenoides chronica
0.419 0.581 0.000
E55 Vitamin D deficiency
0.000 0.581 0.419
E29.9 Testicular dysfunction, unspecified
0.000 0.587 0.413
L43.8 Other lichen planus
0.412 0.588 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.589 0.411
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.589 0.411
E16.4 Abnormal secretion of gastrin
0.000 0.589 0.411
E16.3 Increased secretion of glucagon
0.000 0.589 0.411
E13.8 With unspecified complications
0.000 0.590 0.410
E13.7 With multiple complications
0.000 0.590 0.410
E13.6 With other specified complications
0.000 0.590 0.410
E13.5 With peripheral circulatory complications
0.000 0.590 0.410
E13.4 With neurological complications
0.000 0.590 0.410
E13.2 With renal complications
0.000 0.590 0.410
E13.1 With ketoacidosis
0.000 0.590 0.410
E13.0 With coma
0.000 0.590 0.410
E46 Unspecified protein-energy malnutrition
0.000 0.595 0.405
E29.8 Other testicular dysfunction
0.000 0.597 0.403
E29.0 Testicular hyperfunction
0.000 0.597 0.403
E14.5 With peripheral circulatory complications
0.000 0.599 0.401
E14.2 Withrenal complications
0.000 0.602 0.398
L43.9 Lichen planus, unspecified
0.395 0.604 0.000
E16.1 Other hypoglycaemia
0.000 0.606 0.394
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.606 0.394
E23.1 Drug-induced hypopituitarism
0.000 0.606 0.394
I70.9 Generalised and unspecified atherosclerosis
0.000 0.613 0.387
E14.6 With other specified complications
0.000 0.618 0.382
E13.3 With ophthalmic complications
0.000 0.618 0.381
L43.0 Hypertrophic lichen planus
0.381 0.619 0.000
E06.1 Subacute thyroiditis
0.001 0.620 0.379
E50.9 Vitamin A deficiency, unspecified
0.000 0.621 0.379
E50.8 Other manifestations of vitamin A deficiency
0.000 0.621 0.379
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.621 0.379
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.621 0.379
E50.5 Vitamin A deficiency with night blindness
0.000 0.621 0.379
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.621 0.379
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.621 0.379
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.621 0.379
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.621 0.379
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.621 0.379
E63.9 Nutritional deficiency, unspecified
0.000 0.621 0.379
E63.8 Other specified nutritional deficiencies
0.000 0.621 0.379
E63.1 Imbalance of constituents of food intake
0.000 0.621 0.379
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.621 0.379
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.621 0.379
E64.8 Sequelae of other nutritional deficiencies
0.000 0.621 0.379
E64.3 Sequelae of rickets
0.000 0.621 0.379
E64.2 Sequelae of vitamin C deficiency
0.000 0.621 0.379
E64.1 Sequelae of vitamin A deficiency
0.000 0.621 0.379
E64.0 Sequelae of protein-energy malnutrition
0.000 0.621 0.379
E61 Deficiency of other nutrient elements
0.000 0.622 0.378
L43.3 Subacute (active) lichen planus
0.373 0.626 0.000
L43.2 Lichenoid drug reaction
0.373 0.626 0.000
L43.1 Bullous lichen planus
0.373 0.626 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.627 0.373
E14.7 With multiple complications
0.000 0.628 0.372
E14.0 With coma
0.000 0.628 0.372
E23.6 Other disorders of pituitary gland
0.000 0.628 0.372
E51.9 Thiamine deficiency, unspecified
0.000 0.631 0.368
E51.8 Other manifestations of thiamine deficiency
0.000 0.631 0.368
E51.1 Beriberi
0.000 0.631 0.368
L41.9 Parapsoriasis, unspecified
0.368 0.632 0.000
L41.8 Other parapsoriasis
0.368 0.632 0.000
L41.5 Retiform parapsoriasis
0.368 0.632 0.000
L41.4 Large plaque parapsoriasis
0.368 0.632 0.000
L41.3 Small plaque parapsoriasis
0.368 0.632 0.000
L41.2 Lymphomatoid papulosis
0.368 0.632 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.368 0.632 0.000
I78 Diseases of capillaries
0.000 0.640 0.360
E56.9 Vitamin deficiency, unspecified
0.000 0.640 0.359
E56.8 Deficiency of other vitamins
0.000 0.640 0.359
E56.0 Deficiency of vitamin E
0.000 0.640 0.359
I70.1 Atherosclerosis of renal artery
0.000 0.645 0.355
I70.8 Atherosclerosis of other arteries
0.000 0.646 0.354
E51.2 Wernicke's encephalopathy
0.000 0.646 0.354
E22.0 Acromegaly and pituitary gigantism
0.000 0.648 0.351
E14.1 With ketoacidosis
0.000 0.649 0.351
E24 Cushing's syndrome
0.001 0.650 0.349
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.650 0.350
E28.2 Polycystic ovarian syndrome
0.000 0.652 0.348
E14.3 With ophthalmic complications
0.000 0.652 0.348
E14.4 With neurological complications
0.000 0.655 0.345
D80-D89 Certain disorders involving the immune mechanism
0.000 0.662 0.338
E26.8 Other hyperaldosteronism
0.001 0.662 0.337
E26.1 Secondary hyperaldosteronism
0.001 0.662 0.337
E44.1 Mild protein-energy malnutrition
0.000 0.664 0.335
E44.0 Moderate protein-energy malnutrition
0.000 0.664 0.335
E56.1 Deficiency of vitamin K
0.000 0.668 0.332
D55-D59 Haemolytic anaemias
0.000 0.678 0.322
J84.0 Alveolar and parietoalveolar conditions
0.000 0.679 0.321
D86.9 Sarcoidosis, unspecified
0.000 0.684 0.316
E13.9 Without complications
0.000 0.685 0.315
D86 Sarcoidosis
0.000 0.686 0.314
L44.9 Papulosquamous disorder, unspecified
0.311 0.688 0.000
L44.8 Other specified papulosquamous disorders
0.311 0.688 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.311 0.688 0.000
L44.3 Lichen ruber moniliformis
0.311 0.688 0.000
L44.2 Lichen striatus
0.311 0.688 0.000
L44.1 Lichen nitidus
0.311 0.688 0.000
D59 Acquired haemolytic anaemia
0.000 0.691 0.309
E14.8 With unspecified complications
0.000 0.693 0.306
E04 Other non-toxic goitre
0.000 0.695 0.305
E23.7 Disorder of pituitary gland, unspecified
0.000 0.696 0.304
D50-D53 Nutritional anaemias
0.000 0.696 0.304
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.698 0.302
E55.0 Rickets, active
0.000 0.699 0.300
D59.1 Other autoimmune haemolytic anaemias
0.000 0.705 0.295
I70.0 Atherosclerosis of aorta
0.000 0.706 0.294
D68 Other coagulation defects
0.000 0.706 0.294
E65-E68 Obesity and other hyperalimentation
0.000 0.710 0.290
D80 Immunodeficiency with predominantly antibody defects
0.000 0.710 0.290
E26.9 Hyperaldosteronism, unspecified
0.001 0.712 0.288
L44.0 Pityriasis rubra pilaris
0.284 0.716 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.720 0.280
D50 Iron deficiency anaemia
0.000 0.721 0.279
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.722 0.277
E14.9 Without complications
0.000 0.725 0.275
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.726 0.274
I78.9 Disease of capillaries, unspecified
0.000 0.727 0.273
E61.9 Deficiency of nutrient element, unspecified
0.000 0.729 0.271
E61.8 Deficiency of other specified nutrient elements
0.000 0.729 0.271
E61.7 Deficiency of multiple nutrient elements
0.000 0.729 0.271
E61.6 Vanadium deficiency
0.000 0.729 0.271
E61.5 Molybdenum deficiency
0.000 0.729 0.271
E61.4 Chromium deficiency
0.000 0.729 0.271
E61.3 Manganese deficiency
0.000 0.729 0.271
E61.0 Copper deficiency
0.000 0.729 0.271
E61.2 Magnesium deficiency
0.000 0.734 0.266
E34.0 Carcinoid syndrome
0.001 0.734 0.265
D66 Hereditary factor VIII deficiency
0.000 0.735 0.265
D83 Common variable immunodeficiency
0.000 0.737 0.263
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.742 0.258
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.745 0.255
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.746 0.254
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.746 0.254
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.746 0.254
D84 Other immunodeficiencies
0.000 0.749 0.251
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.749 0.251
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.749 0.250
E24.3 Ectopic ACTH syndrome
0.001 0.749 0.250
E24.1 Nelson's syndrome
0.001 0.749 0.250
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.751 0.249
E04.0 Non-toxic diffuse goitre
0.000 0.752 0.248
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.752 0.248
D50.9 Iron deficiency anaemia, unspecified
0.000 0.752 0.248
I78.8 Other diseases of capillaries
0.000 0.753 0.247
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.753 0.246
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.755 0.245
J33 Nasal polyp
0.000 0.755 0.245
D81 Combined immunodeficiencies
0.000 0.757 0.242
D52 Folate deficiency anaemia
0.000 0.758 0.242
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.759 0.241
E24.8 Other Cushing's syndrome
0.001 0.763 0.236
E24.2 Drug-induced Cushing's syndrome
0.001 0.764 0.235
D67 Hereditary factor IX deficiency
0.000 0.764 0.236
D58 Other hereditary haemolytic anaemias
0.000 0.767 0.233
E29.1 Testicular hypofunction
0.000 0.768 0.232
D82 Immunodeficiency associated with other major defects
0.000 0.768 0.232
D55 Anaemia due to enzyme disorders
0.000 0.769 0.231
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.773 0.226
D50.8 Other iron deficiency anaemias
0.000 0.775 0.225
D53 Other nutritional anaemias
0.000 0.778 0.222
D59.8 Other acquired haemolytic anaemias
0.000 0.778 0.222
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.778 0.222
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.778 0.222
D59.3 Haemolytic-uraemic syndrome
0.000 0.778 0.222
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.778 0.222
D57 Sickle-cell disorders
0.000 0.781 0.219
E04.8 Other specified non-toxic goitre
0.000 0.781 0.219
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.782 0.218
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.783 0.217
D68.5 Primary Thrombophilia
0.000 0.783 0.217
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.783 0.217
D86.1 Sarcoidosis of lymph nodes
0.000 0.784 0.216
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.787 0.213
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.789 0.211
D68.9 Coagulation defect, unspecified
0.000 0.790 0.210
D83.9 Common variable immunodeficiency, unspecified
0.000 0.791 0.209
E67 Other hyperalimentation
0.000 0.792 0.208
E68 Sequelae of hyperalimentation
0.000 0.792 0.208
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.792 0.208
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.792 0.208
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.792 0.208
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.792 0.208
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.792 0.208
E07.9 Disorder of thyroid, unspecified
0.000 0.793 0.207
D56 Thalassaemia
0.000 0.795 0.205
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.795 0.205
D86.3 Sarcoidosis of skin
0.000 0.797 0.203
J33.8 Other polyp of sinus
0.000 0.798 0.202
D50.1 Sideropenic dysphagia
0.000 0.800 0.200
D68.1 Hereditary factor XI deficiency
0.000 0.800 0.200
D58.0 Hereditary spherocytosis
0.000 0.801 0.199
E26.0 Primary hyperaldosteronism
0.001 0.802 0.197
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.802 0.198
D52.9 Folate deficiency anaemia, unspecified
0.000 0.803 0.197
E24.0 Pituitary-dependent Cushing's disease
0.001 0.803 0.196
D68.4 Acquired coagulation factor deficiency
0.000 0.804 0.196
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.808 0.192
E55.9 Vitamin D deficiency, unspecified
0.000 0.809 0.191
J33.1 Polypoid sinus degeneration
0.000 0.810 0.190
J81 Pulmonary oedema
0.000 0.810 0.190
D68.2 Hereditary deficiency of other clotting factors
0.000 0.811 0.189
D83.8 Other common variable immunodeficiencies
0.000 0.811 0.189
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.811 0.189
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.811 0.189
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.811 0.189
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.812 0.188
D84.1 Defects in the complement system
0.000 0.812 0.188
D84.9 Immunodeficiency, unspecified
0.000 0.814 0.186
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.816 0.184
D68.6 Other Thrombophilia
0.000 0.817 0.183
M35.0 Sicca syndrome [Sjogren]
0.000 0.817 0.183
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.818 0.182
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.819 0.180
M35.3 Polymyalgia rheumatica
0.000 0.820 0.180
D89.3 Immune reconstitution syndrome
0.000 0.820 0.180
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.821 0.179
D68.0 Von Willebrand's disease
0.000 0.821 0.179
M35 Other systemic involvement of connective tissue
0.000 0.823 0.177
D84.8 Other specified immunodeficiencies
0.000 0.824 0.175
D81.9 Combined immunodeficiency, unspecified
0.000 0.826 0.174
D81.8 Other combined immunodeficiencies
0.000 0.826 0.174
D81.7 Major histocompatibility complex class II deficiency
0.000 0.826 0.174
D81.6 Major histocompatibility complex class I deficiency
0.000 0.826 0.174
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.826 0.174
D81.4 Nezelof's syndrome
0.000 0.826 0.174
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.826 0.174
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.826 0.174
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.826 0.174
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.826 0.174
D52.8 Other folate deficiency anaemias
0.000 0.826 0.173
D52.1 Drug-induced folate deficiency anaemia
0.000 0.826 0.173
D52.0 Dietary folate deficiency anaemia
0.000 0.826 0.173
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.827 0.173
J80 Adult respiratory distress syndrome
0.000 0.831 0.169
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.832 0.168
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.001 0.832 0.167
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.833 0.167
D58.1 Hereditary elliptocytosis
0.000 0.833 0.167
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.834 0.166
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.834 0.166
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.834 0.166
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.834 0.166
D82.2 Immunodeficiency with short-limbed stature
0.000 0.834 0.166

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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