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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2516464
log Bayes Factor = 119.659
Chromosome 6   position 31,416,156  (GRCh37) Explore rs2516464 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
M45 Ankylosing spondylitis
0.000 0.004 0.996
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.009 0.991
E10 Insulin-dependent diabetes mellitus
0.000 0.016 0.984
E10.9 Without complications
0.000 0.017 0.983
E10-E14 Diabetes mellitus
0.000 0.024 0.976
E14 Unspecified diabetes mellitus
0.000 0.040 0.960
E14.3 With ophthalmic complications
0.000 0.048 0.952
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.049 0.951
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.064 0.936
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.067 0.933
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.068 0.932
E10.3 With ophthalmic complications
0.000 0.071 0.929
C85.1 B-cell lymphoma, unspecified
0.000 0.072 0.928
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.088 0.912
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.089 0.911
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.095 0.905
J45.9 Asthma, unspecified
0.000 0.096 0.904
E07 Other disorders of thyroid
0.000 0.100 0.900
E10.2 With renal complications
0.000 0.113 0.887
E10.1 With ketoacidosis
0.000 0.127 0.873
E03.8 Other specified hypothyroidism
0.000 0.138 0.862
E83.1 Disorders of iron metabolism
0.862 0.138 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.158 0.842
E07.9 Disorder of thyroid, unspecified
0.000 0.159 0.841
C83.3 Large cell (diffuse)
0.000 0.162 0.838
E06 Thyroiditis
0.000 0.201 0.799
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.215 0.785
E14.2 Withrenal complications
0.000 0.222 0.778
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.230 0.770
C82.3 Follicular lymphoma grade IIIa
0.000 0.234 0.766
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.242 0.758
E10.8 With unspecified complications
0.000 0.245 0.755
C81 Hodgkin's disease
0.000 0.255 0.745
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.262 0.738
E10.7 With multiple complications
0.000 0.274 0.726
E10.6 With other specified complications
0.000 0.275 0.725
E14.5 With peripheral circulatory complications
0.000 0.276 0.723
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.286 0.714
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.286 0.714
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.286 0.714
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.286 0.714
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.286 0.714
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.286 0.714
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.287 0.712
E14.1 With ketoacidosis
0.000 0.289 0.711
E14.8 With unspecified complications
0.000 0.290 0.710
C82.2 Large cell, follicular
0.000 0.295 0.705
E12 Malnutrition-related diabetes mellitus
0.000 0.300 0.699
C82.0 Small cleaved cell, follicular
0.000 0.301 0.699
E05.8 Other thyrotoxicosis
0.000 0.306 0.694
E10.4 With neurological complications
0.000 0.306 0.694
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.307 0.693
E14.7 With multiple complications
0.000 0.312 0.688
E14.6 With other specified complications
0.000 0.312 0.687
C83.7 Burkitt's tumour
0.000 0.315 0.685
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.315 0.685
C82.4 Follicular lymphoma grade IIIb
0.000 0.326 0.674
E06.3 Autoimmune thyroiditis
0.000 0.332 0.668
E14.4 With neurological complications
0.000 0.334 0.666
E14.0 With coma
0.000 0.334 0.666
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.335 0.665
C86 Other specified types of T/NK-cell lymphoma
0.000 0.335 0.665
C88 Malignant immunoproliferative diseases
0.000 0.337 0.663
E03.1 Congenital hypothyroidism without goitre
0.000 0.346 0.654
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.346 0.653
C82.6 Cutaneous follicle centre lymphoma
0.000 0.347 0.653
C82.5 Diffuse follicle centre lymphoma
0.000 0.347 0.653
C81.9 Hodgkin's disease, unspecified
0.000 0.348 0.652
E07.1 Dyshormogenetic goitre
0.000 0.355 0.645
E07.0 Hypersecretion of calcitonin
0.000 0.355 0.645
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.371 0.629
C85.0 Lymphosarcoma
0.000 0.372 0.627
E13 Other specified diabetes mellitus
0.000 0.380 0.620
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.381 0.619
E06.5 Other chronic thyroiditis
0.000 0.385 0.615
C84.5 Other and unspecified T-cell lymphomas
0.000 0.388 0.612
C83.6 Undifferentiated (diffuse)
0.000 0.396 0.604
C83.5 Lymphoblastic (diffuse)
0.000 0.396 0.604
C83.4 Immunoblastic (diffuse)
0.000 0.396 0.604
C83.2 Mixed small and large cell (diffuse)
0.000 0.396 0.604
C94 Other leukaemias of specified cell type
0.000 0.397 0.603
E10.0 With coma
0.000 0.407 0.593
E07.8 Other specified disorders of thyroid
0.000 0.414 0.586
C81.2 Mixed cellularity
0.000 0.418 0.582
C84.0 Mycosis fungoides
0.000 0.419 0.581
E06.4 Drug-induced thyroiditis
0.000 0.427 0.573
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.427 0.573
E06.0 Acute thyroiditis
0.000 0.427 0.573
E40-E46 Malnutrition
0.000 0.432 0.568
C93 Monocytic leukaemia
0.000 0.432 0.567
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.443 0.556
E06.9 Thyroiditis, unspecified
0.000 0.450 0.549
E10.5 With peripheral circulatory complications
0.000 0.451 0.549
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.452 0.548
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.456 0.543
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.456 0.543
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.456 0.543
C84.3 Lymphoepithelioid lymphoma
0.000 0.456 0.543
C84.2 T-zone lymphoma
0.000 0.456 0.543
C84.1 Sezary's diease
0.000 0.456 0.543
C95 Leukaemia of unspecified cell type
0.000 0.459 0.541
C83.1 Small cleaved cell (diffuse)
0.000 0.463 0.536
C91 Lymphoid leukaemia
0.000 0.464 0.536
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.466 0.534
C81.3 Lymphocytic depletion
0.000 0.466 0.534
E06.1 Subacute thyroiditis
0.000 0.475 0.524
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
C81.1 Nodular sclerosis
0.000 0.492 0.508
C81.7 Other Hodgkin's disease
0.000 0.492 0.508
E12.9 Without complications
0.000 0.498 0.501
E12.8 With unspecified complications
0.000 0.498 0.501
E12.7 With multiple complications
0.000 0.498 0.501
E12.6 With other specified complications
0.000 0.498 0.501
E12.5 With peripheral circulatory complications
0.000 0.498 0.501
E12.4 With neurological complications
0.000 0.498 0.501
E12.3 With ophthalmic complications
0.000 0.498 0.501
E12.2 With renal complications
0.000 0.498 0.501
E12.1 With ketoacidosis
0.000 0.498 0.501
E12.0 With coma
0.000 0.498 0.501
E16 Other disorders of pancreatic internal secretion
0.000 0.507 0.493
E15 Nondiabetic hypoglycaemic coma
0.000 0.509 0.491
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.512 0.488
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.513 0.486
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.523 0.477
C86.4 Blastic NK-cell lymphoma
0.000 0.523 0.477
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.523 0.477
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.523 0.477
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.523 0.477
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.523 0.477
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.524 0.476
C88.7 Other malignant immunoproliferative diseases
0.000 0.524 0.476
C88.3 Immunoproliferative small intestinal disease
0.000 0.524 0.476
C88.2 Gamma heavy chain disease
0.000 0.524 0.476
C88.1 Alpha heavy chain disease
0.000 0.524 0.476
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.531 0.469
C96.8 Histiocytic sarcoma
0.000 0.531 0.469
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.531 0.469
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.531 0.469
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.531 0.469
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.531 0.469
C96.3 True histiocytic lymphoma
0.000 0.531 0.469
C96.2 Malignant mast cell tumour
0.000 0.531 0.469
C96.1 Malignant histiocytosis
0.000 0.531 0.469
C96.0 Letterer-Siwe disease
0.000 0.531 0.469
C81.0 Lymphocytic predominance
0.000 0.535 0.465
C91.9 Lymphoid leukaemia, unspecified
0.000 0.537 0.463
E13.3 With ophthalmic complications
0.000 0.539 0.461
C84.4 Peripheral T-cell lymphoma
0.000 0.544 0.456
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.548 0.451
E13.8 With unspecified complications
0.000 0.555 0.444
E13.7 With multiple complications
0.000 0.555 0.444
E13.6 With other specified complications
0.000 0.555 0.444
E13.5 With peripheral circulatory complications
0.000 0.555 0.444
E13.4 With neurological complications
0.000 0.555 0.444
E13.2 With renal complications
0.000 0.555 0.444
E13.1 With ketoacidosis
0.000 0.555 0.444
E13.0 With coma
0.000 0.555 0.444
C94.7 Other specified leukaemias
0.000 0.567 0.432
C94.5 Acute myelofibrosis
0.000 0.567 0.432
C94.4 Acute panmyelosis
0.000 0.567 0.432
C94.3 Mast cell leukaemia
0.000 0.567 0.432
C94.2 Acute megakaryoblastic leukaemia
0.000 0.567 0.432
C94.1 Chronic erythraemia
0.000 0.567 0.432
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.567 0.432
C91.5 Adult T-cell leukaemia
0.000 0.580 0.420
C95.9 Leukaemia, unspecified
0.000 0.587 0.413
E16.1 Other hypoglycaemia
0.000 0.588 0.412
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.592 0.407
E45 Retarded development following protein-energy malnutrition
0.000 0.592 0.407
E43 Unspecified severe protein-energy malnutrition
0.000 0.592 0.407
E42 Marasmic kwashiorkor
0.000 0.592 0.407
E41 Nutritional marasmus
0.000 0.592 0.407
E40 Kwashiorkor
0.000 0.592 0.407
C93.9 Monocytic leukaemia, unspecified
0.000 0.593 0.407
C93.7 Other monocytic leukaemia
0.000 0.593 0.407
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.593 0.407
C93.2 Subacute monocytic leukaemia
0.000 0.593 0.407
C93.0 Acute monocytic leukaemia
0.000 0.593 0.407
C92 Myeloid leukaemia
0.000 0.604 0.396
C95.7 Other leukaemia of unspecified cell type
0.000 0.612 0.388
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.612 0.388
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.616 0.384
C91.7 Other lymphoid leukaemia
0.000 0.616 0.384
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.616 0.384
C91.3 Prolymphocytic leukaemia
0.000 0.616 0.384
C91.2 Subacute lymphocytic leukaemia
0.000 0.616 0.384
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.618 0.382
K90 Intestinal malabsorption
0.000 0.622 0.378
C91.0 Acute lymphoblastic leukaemia
0.000 0.636 0.364
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.645 0.355
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.646 0.354
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.646 0.354
E16.4 Abnormal secretion of gastrin
0.000 0.646 0.354
E16.3 Increased secretion of glucagon
0.000 0.646 0.354
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.649 0.351
C92.1 Chronic myeloid leukaemia
0.000 0.649 0.351
E50-E64 Other nutritional deficiencies
0.000 0.650 0.350
E13.9 Without complications
0.000 0.662 0.338
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.664 0.335
E14.9 Without complications
0.000 0.668 0.332
C93.1 Chronic monocytic leukaemia
0.001 0.679 0.320
C95.0 Acute leukaemia of unspecified cell type
0.001 0.696 0.303
E46 Unspecified protein-energy malnutrition
0.000 0.706 0.293
E44.1 Mild protein-energy malnutrition
0.000 0.708 0.292
E44.0 Moderate protein-energy malnutrition
0.000 0.708 0.292
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.716 0.284
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.716 0.284
C92.3 Myeloid sarcoma
0.000 0.716 0.284
C92.2 Subacute myeloid leukaemia
0.000 0.716 0.284
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.716 0.284
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.002 0.725 0.274
E58 Dietary calcium deficiency
0.000 0.725 0.275
K90.9 Intestinal malabsorption, unspecified
0.000 0.725 0.275
C92.5 Acute myelomonocytic leukaemia
0.000 0.725 0.274
K90.3 Pancreatic steatorrhoea
0.000 0.729 0.271
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.729 0.271
K90.1 Tropical sprue
0.000 0.729 0.271
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.001 0.743 0.256
E16.2 Hypoglycaemia, unspecified
0.000 0.744 0.256
C91.1 Chronic lymphocytic leukaemia
0.000 0.747 0.253
C90 Multiple myeloma and malignant plasma cell neoplasms
0.001 0.747 0.252
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.749 0.251
E63 Other nutritional deficiencies
0.000 0.749 0.251
E50 Vitamin A deficiency
0.000 0.749 0.251
E60 Dietary zinc deficiency
0.000 0.749 0.251
E59 Dietary selenium deficiency
0.000 0.749 0.251
E52 Niacin deficiency [pellagra]
0.000 0.749 0.251
E65-E68 Obesity and other hyperalimentation
0.000 0.750 0.249
C92.9 Myeloid leukaemia, unspecified
0.000 0.753 0.247
C92.7 Other myeloid leukaemia
0.000 0.756 0.243
E51 Thiamine deficiency
0.000 0.761 0.239
E54 Ascorbic acid deficiency
0.000 0.768 0.232
E56 Other vitamin deficiencies
0.000 0.772 0.228
E61 Deficiency of other nutrient elements
0.000 0.779 0.221
K90.8 Other intestinal malabsorption
0.000 0.780 0.219
E55 Vitamin D deficiency
0.000 0.781 0.219
C92.4 Acute promyelocytic leukaemia
0.000 0.786 0.214
C91.4 Hairy-cell leukaemia
0.001 0.809 0.190
C90.1 Plasma cell leukaemia
0.000 0.815 0.184
C90.3 Solitary plasmacytoma
0.000 0.816 0.184
E50.9 Vitamin A deficiency, unspecified
0.000 0.820 0.180
E50.8 Other manifestations of vitamin A deficiency
0.000 0.820 0.180
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.820 0.180
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.820 0.180
E50.5 Vitamin A deficiency with night blindness
0.000 0.820 0.180
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.820 0.180
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.820 0.180
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.820 0.180
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.820 0.180
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.820 0.180
E63.9 Nutritional deficiency, unspecified
0.000 0.820 0.180
E63.8 Other specified nutritional deficiencies
0.000 0.820 0.180
E63.1 Imbalance of constituents of food intake
0.000 0.820 0.180
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.820 0.180
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.820 0.180
E64.8 Sequelae of other nutritional deficiencies
0.000 0.820 0.180
E64.3 Sequelae of rickets
0.000 0.820 0.180
E64.2 Sequelae of vitamin C deficiency
0.000 0.820 0.180
E64.1 Sequelae of vitamin A deficiency
0.000 0.820 0.180
E64.0 Sequelae of protein-energy malnutrition
0.000 0.820 0.180
E67 Other hyperalimentation
0.001 0.821 0.179
E68 Sequelae of hyperalimentation
0.001 0.821 0.179
J45 Asthma
0.000 0.823 0.177
E51.9 Thiamine deficiency, unspecified
0.000 0.828 0.171
E51.8 Other manifestations of thiamine deficiency
0.000 0.828 0.171
E51.1 Beriberi
0.000 0.828 0.171
E56.9 Vitamin deficiency, unspecified
0.000 0.836 0.163
E56.8 Deficiency of other vitamins
0.000 0.836 0.163
E56.0 Deficiency of vitamin E
0.000 0.836 0.163
E61.2 Magnesium deficiency
0.000 0.837 0.163
E51.2 Wernicke's encephalopathy
0.000 0.840 0.160
E61.9 Deficiency of nutrient element, unspecified
0.000 0.841 0.159
E61.8 Deficiency of other specified nutrient elements
0.000 0.841 0.159
E61.7 Deficiency of multiple nutrient elements
0.000 0.841 0.159
E61.6 Vanadium deficiency
0.000 0.841 0.159
E61.5 Molybdenum deficiency
0.000 0.841 0.159
E61.4 Chromium deficiency
0.000 0.841 0.159
E61.3 Manganese deficiency
0.000 0.841 0.159
E61.0 Copper deficiency
0.000 0.841 0.159
E55.0 Rickets, active
0.000 0.843 0.157
E83 Disorders of mineral metabolism
0.148 0.851 0.002
E53 Deficiency of other B group vitamins
0.000 0.851 0.149
E04 Other non-toxic goitre
0.000 0.852 0.148
E56.1 Deficiency of vitamin K
0.000 0.860 0.140
E67.8 Other specified hyperalimentation
0.001 0.871 0.128
E67.3 Hypervitaminosis D
0.001 0.871 0.128
E67.2 Megavitamin-B6 syndrome
0.001 0.871 0.128
E67.1 Hypercarotenaemia
0.001 0.871 0.128
E67.0 Hypervitaminosis A
0.001 0.871 0.128
C83.0 Small cell (diffuse)
0.007 0.873 0.120
J45.8 Mixed asthma
0.000 0.873 0.127
J45.1 Nonallergic asthma
0.000 0.874 0.126
E55.9 Vitamin D deficiency, unspecified
0.000 0.875 0.125
E61.1 Iron deficiency
0.000 0.878 0.122
E83.9 Disorder of mineral metabolism, unspecified
0.115 0.884 0.001
C92.0 Acute myeloid leukaemia
0.000 0.888 0.112
E83.8 Other disorders of mineral metabolism
0.106 0.893 0.001
E83.2 Disorders of zinc metabolism
0.106 0.893 0.001
E83.0 Disorders of copper metabolism
0.106 0.893 0.001
E53.1 Pyridoxine deficiency
0.000 0.893 0.107
E53.0 Riboflavin deficiency
0.000 0.893 0.107
E04.8 Other specified non-toxic goitre
0.000 0.893 0.106
E83.3 Disorders of phosphorus metabolism
0.100 0.899 0.001
E53.9 Vitamin B deficiency, unspecified
0.000 0.901 0.099
E65 Localised adiposity
0.001 0.903 0.096
E04.0 Non-toxic diffuse goitre
0.000 0.908 0.092
C90.2 Plasmacytoma, extramedullary
0.001 0.916 0.083
E83.5 Disorders of calcium metabolism
0.082 0.918 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.925 0.075
K60.2 Anal fissure, unspecified
0.000 0.929 0.071
E20-E35 Disorders of other endocrine glands
0.000 0.930 0.070
E28 Ovarian dysfunction
0.000 0.939 0.061
E04.9 Non-toxic goitre, unspecified
0.000 0.940 0.060
E24 Cushing's syndrome
0.000 0.944 0.056
E29 Testicular dysfunction
0.000 0.946 0.054
G35 Multiple sclerosis
0.054 0.946 0.000
E28.3 Primary ovarian failure
0.000 0.948 0.052
E25 Adrenogenital disorders
0.000 0.949 0.051
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.950 0.050
E32 Diseases of thymus
0.000 0.950 0.050
E31 Polyglandular dysfunction
0.000 0.950 0.050
E30 Disorders of puberty, not elsewhere classified
0.000 0.950 0.050
K60 Fissure and fistula of anal and rectal regions
0.000 0.951 0.049
E28.2 Polycystic ovarian syndrome
0.000 0.952 0.048
E24.9 Cushing's syndrome, unspecified
0.000 0.954 0.045
E24.2 Drug-induced Cushing's syndrome
0.000 0.955 0.045
E28.9 Ovarian dysfunction, unspecified
0.000 0.956 0.044
E28.8 Other ovarian dysfunction
0.000 0.956 0.044
E28.1 Androgen excess
0.000 0.956 0.044
E28.0 Oestrogen excess
0.000 0.956 0.044
K60.5 Anorectal fistula
0.000 0.957 0.043
E29.1 Testicular hypofunction
0.000 0.958 0.042
K60.0 Acute anal fissure
0.000 0.958 0.042
K60.4 Rectal fistula
0.000 0.959 0.041
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.960 0.040
E24.3 Ectopic ACTH syndrome
0.000 0.960 0.040
E24.1 Nelson's syndrome
0.000 0.960 0.040
E23 Hypofunction and other disorders of pituitary gland
0.000 0.960 0.040
E24.0 Pituitary-dependent Cushing's disease
0.000 0.961 0.039
E26 Hyperaldosteronism
0.000 0.961 0.039
G35-G37 Demyelinating diseases of the central nervous system
0.039 0.961 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.961 0.039
E29.8 Other testicular dysfunction
0.000 0.961 0.039
E29.0 Testicular hyperfunction
0.000 0.961 0.039
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.962 0.038
E24.8 Other Cushing's syndrome
0.000 0.963 0.037
M45-M49 Spondylopathies
0.000 0.963 0.037
E25.9 Adrenogenital disorder, unspecified
0.000 0.963 0.037
E25.8 Other adrenogenital disorders
0.000 0.963 0.037
E30.9 Disorder of puberty, unspecified
0.000 0.964 0.036
E30.8 Other disorders of puberty
0.000 0.964 0.036
E30.1 Precocious puberty
0.000 0.964 0.036
E30.0 Delayed puberty
0.000 0.964 0.036
E31.9 Polyglandular dysfunction, unspecified
0.000 0.964 0.036
E31.8 Other polyglandular dysfunction
0.000 0.964 0.036
E31.1 Polyglandular hyperfunction
0.000 0.964 0.036
E31.0 Autoimmune polyglandular failure
0.000 0.964 0.036
E32.9 Disease of thymus, unspecified
0.000 0.964 0.036
E32.8 Other diseases of thymus
0.000 0.964 0.036
E32.1 Abscess of thymus
0.000 0.964 0.036
E32.0 Persistent hyperplasia of thymus
0.000 0.964 0.036
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.964 0.036
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.964 0.036
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.964 0.036
G37 Other demyelinating diseases of central nervous system
0.036 0.964 0.000
E83.4 Disorders of magnesium metabolism
0.035 0.964 0.001
G37.9 Demyelinating disease of central nervous system, unspecified
0.036 0.964 0.000
E20 Hypoparathyroidism
0.001 0.965 0.035
F20.9 Schizophrenia, unspecified
0.035 0.965 0.000
C90.0 Multiple myeloma
0.001 0.965 0.034
E22 Hyperfunction of pituitary gland
0.000 0.967 0.033
L40.9 Psoriasis, unspecified
0.033 0.967 0.000
E23.2 Diabetes insipidus
0.000 0.968 0.032
F20 Schizophrenia
0.031 0.969 0.000
J45.0 Predominantly allergic asthma
0.000 0.969 0.031
G37.8 Other specified demyelinating diseases of central nervous system
0.029 0.971 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.971 0.029
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.971 0.029
E23.1 Drug-induced hypopituitarism
0.000 0.971 0.029
E23.6 Other disorders of pituitary gland
0.000 0.971 0.029
E26.8 Other hyperaldosteronism
0.000 0.972 0.028
E26.1 Secondary hyperaldosteronism
0.000 0.972 0.028
E53.8 Deficiency of other specified B group vitamins
0.000 0.972 0.028
G36 Other acute disseminated demyelination
0.027 0.972 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.973 0.027
E26.9 Hyperaldosteronism, unspecified
0.000 0.973 0.027
F20.0 Paranoid schizophrenia
0.027 0.973 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.974 0.026
G37.5 Concentric sclerosis [Balo]
0.026 0.974 0.000
G37.4 Subacute necrotising myelitis
0.026 0.974 0.000
G37.2 Central pontine myelinolysis
0.026 0.974 0.000
G37.1 Central demyelination of corpus callosum
0.026 0.974 0.000
G37.0 Diffuse sclerosis
0.026 0.974 0.000
K60.1 Chronic anal fissure
0.000 0.974 0.026
M49 Spondylopathies in diseases classified elsewhere
0.000 0.974 0.026
E20.8 Other hypoparathyroidism
0.001 0.974 0.025
E20.0 Idiopathic hypoparathyroidism
0.001 0.974 0.025
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.024 0.976 0.000
E70-E90 Metabolic disorders
0.006 0.976 0.018
E22.8 Other hyperfunction of pituitary gland
0.000 0.976 0.024
E23.7 Disorder of pituitary gland, unspecified
0.000 0.976 0.024
E20.1 Pseudohypoparathyroidism
0.001 0.976 0.023
K60.3 Anal fistula
0.000 0.976 0.024
F20.2 Catatonic schizophrenia
0.023 0.976 0.000
E34 Other endocrine disorders
0.001 0.976 0.023
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.977 0.023
F22 Persistent delusional disorders
0.023 0.977 0.000
F20.5 Residual schizophrenia
0.023 0.977 0.000
F22.0 Delusional disorder
0.023 0.977 0.000
F60.3 Emotionally unstable personality disorder
0.023 0.977 0.000
F20.8 Other schizophrenia
0.022 0.977 0.000
F20.6 Simple schizophrenia
0.022 0.977 0.000
F20.4 Postschizophrenic depression
0.022 0.977 0.000
F20.3 Undifferentiated schizophrenia
0.022 0.977 0.000
F20.1 Hebephrenic schizophrenia
0.022 0.977 0.000
F60-F69 Disorders of adult personality and behaviour
0.022 0.978 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.978 0.022
F60 Specific personality disorders
0.022 0.978 0.000
K90-K93 Other diseases of the digestive system
0.000 0.978 0.022
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.021 0.979 0.000
Chapter V Mental and behavioural disorders
0.021 0.979 0.000
G36.9 Acute disseminated demyelination, unspecified
0.020 0.980 0.000
G36.8 Other specified acute disseminated demyelination
0.020 0.980 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.020 0.980 0.000
F69 Unspecified disorder of adult personality and behaviour
0.020 0.980 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.020 0.980 0.000
G36.0 Neuromyelitis optica [Devic]
0.019 0.981 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.019 0.981 0.000
E26.0 Primary hyperaldosteronism
0.000 0.981 0.019
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.981 0.019
M49.4 Neuropathic spondylopathy
0.000 0.981 0.019
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.981 0.019
M49.2 Enterobacterial spondylitis
0.000 0.981 0.019
M49.1 Brucella spondylitis
0.000 0.981 0.019
M49.0 Tuberculosis of spine
0.000 0.981 0.019
E73 Lactose intolerance
0.003 0.981 0.015
E22.1 Hyperprolactinaemia
0.000 0.981 0.018
F11 Mental and behavioural disorders due to use of opioids
0.019 0.981 0.000
E27 Other disorders of adrenal gland
0.000 0.982 0.018
E23.0 Hypopituitarism
0.000 0.982 0.018
G51.0 Bell's palsy
0.000 0.982 0.018
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.018 0.982 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.018 0.982 0.000
F60.9 Personality disorder, unspecified
0.018 0.982 0.000
E70 Disorders of aromatic amino-acid metabolism
0.004 0.982 0.014
F12.1 Harmful use
0.018 0.982 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.982 0.018
E66 Obesity
0.000 0.982 0.017
F28 Other nonorganic psychotic disorders
0.018 0.982 0.000
F24 Induced delusional disorder
0.018 0.982 0.000
F21 Schizotypal disorder
0.018 0.982 0.000
F60.0 Paranoid personality disorder
0.018 0.982 0.000
E77 Disorders of glycoprotein metabolism
0.005 0.982 0.013
E76 Disorders of glycosaminoglycan metabolism
0.005 0.982 0.013
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.005 0.982 0.013
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.005 0.982 0.013
F03 Unspecified dementia
0.017 0.983 0.000
F19.1 Harmful use
0.017 0.983 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.005 0.983 0.013
F23 Acute and transient psychotic disorders
0.017 0.983 0.000
C61 Malignant neoplasm of prostate
0.017 0.983 0.000
E84 Cystic fibrosis
0.005 0.983 0.012
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.983 0.017
E34.5 Androgen resistance syndrome
0.001 0.983 0.017
E34.4 Constitutional tall stature
0.001 0.983 0.017
E34.3 Short stature, not elsewhere classified
0.001 0.983 0.017
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.983 0.017
E34.1 Other hypersecretion of intestinal hormones
0.001 0.983 0.017
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.983 0.017
E72 Other disorders of amino-acid metabolism
0.005 0.983 0.012
F64 Gender identity disorders
0.017 0.983 0.000
F60.2 Dissocial personality disorder
0.017 0.983 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.983 0.017
F22.9 Persistent delusional disorder, unspecified
0.017 0.983 0.000
F22.8 Other persistent delusional disorders
0.017 0.983 0.000
E21.2 Other hyperparathyroidism
0.000 0.983 0.017
M46 Other inflammatory spondylopathies
0.000 0.983 0.017

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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