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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2516472
log Bayes Factor = 23.2465
Chromosome 6   position 31,394,700  (GRCh37) Explore rs2516472 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.003 0.997
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.004 0.996
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.009 0.991
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.009 0.991
E10.9 Without complications
0.000 0.012 0.988
Chapter I Certain infectious and parasitic diseases
0.000 0.014 0.986
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.015 0.985
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.021 0.979
D50-D53 Nutritional anaemias
0.000 0.022 0.978
E10.3 With ophthalmic complications
0.000 0.025 0.975
D50 Iron deficiency anaemia
0.000 0.027 0.973
L57.0 Actinic keratosis
0.000 0.029 0.971
M07 Psoriatic and enteropathic arthropathies
0.000 0.029 0.971
D50.9 Iron deficiency anaemia, unspecified
0.000 0.030 0.970
B25-B34 Other viral diseases
0.000 0.033 0.967
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.039 0.961
M07.3 Other psoriatic arthropathies
0.000 0.050 0.950
B34 Viral infection of unspecified site
0.000 0.053 0.947
L08 Other local infections of skin and subcutaneous tissue
0.000 0.058 0.942
B35-B49 Mycoses
0.000 0.063 0.937
D60-D64 Aplastic and other anaemias
0.000 0.063 0.937
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.065 0.935
B34.9 Viral infection, unspecified
0.000 0.067 0.933
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.000 0.067 0.933
L20-L30 Dermatitis and eczema
0.000 0.076 0.924
M20-M25 Other joint disorders
0.000 0.076 0.924
M35 Other systemic involvement of connective tissue
0.000 0.078 0.922
E50-E64 Other nutritional deficiencies
0.000 0.079 0.921
C44 Other malignant neoplasms of skin
0.000 0.081 0.919
C44.3 Skin of other and unspecified parts of face
0.000 0.082 0.918
M35.3 Polymyalgia rheumatica
0.000 0.085 0.915
E10.1 With ketoacidosis
0.000 0.087 0.913
M06.0 Seronegative rheumatoid arthritis
0.000 0.088 0.912
B37 Candidiasis
0.000 0.089 0.911
D64 Other anaemias
0.000 0.089 0.911
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.091 0.909
R47-R49 Symptoms and signs involving speech and voice
0.000 0.093 0.907
E06 Thyroiditis
0.000 0.094 0.906
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.096 0.904
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.096 0.904
C44.4 Skin of scalp and neck
0.000 0.098 0.902
B37.8 Candidiasis of other sites
0.000 0.098 0.902
M45-M49 Spondylopathies
0.000 0.100 0.900
Chapter II Neoplasms
0.000 0.101 0.899
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.000 0.104 0.896
R41 Other symptoms and signs involving cognitive functions and awareness
0.000 0.106 0.894
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.107 0.893
D64.9 Anaemia, unspecified
0.000 0.107 0.893
D80-D89 Certain disorders involving the immune mechanism
0.000 0.109 0.891
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.109 0.891
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.116 0.884
M45 Ankylosing spondylitis
0.000 0.118 0.882
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.000 0.119 0.881
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.120 0.880
M05 Seropositive rheumatoid arthritis
0.000 0.125 0.875
R41.0 Disorientation, unspecified
0.000 0.126 0.874
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.129 0.871
Chapter IX Diseases of the circulatory system
0.000 0.130 0.870
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.131 0.869
R47 Speech disturbances, not elsewhere classified
0.000 0.134 0.866
E65-E68 Obesity and other hyperalimentation
0.000 0.138 0.862
I60-I69 Cerebrovascular diseases
0.000 0.141 0.859
R41.3 Other amnesia
0.000 0.145 0.855
E53 Deficiency of other B group vitamins
0.000 0.148 0.852
Chapter VIII Diseases of the ear and mastoid process
0.000 0.149 0.851
E10.4 With neurological complications
0.000 0.150 0.850
R26 Abnormalities of gait and mobility
0.000 0.151 0.849
L29 Pruritus
0.000 0.152 0.848
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.156 0.844
E06.3 Autoimmune thyroiditis
0.000 0.165 0.835
D86 Sarcoidosis
0.000 0.169 0.831
R47.0 Dysphasia and aphasia
0.000 0.173 0.827
C44.1 Skin of eyelid, including canthus
0.000 0.176 0.824
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.183 0.817
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.183 0.817
M35.0 Sicca syndrome [Sjogren]
0.000 0.184 0.816
C64-C68 Malignant neoplasms of urinary tract
0.000 0.186 0.814
L40.0 Psoriasis vulgaris
0.000 0.188 0.812
R26.8 Other and unspecified abnormalities of gait and mobility
0.000 0.188 0.812
B35 Dermatophytosis
0.000 0.188 0.811
R93 Abnormal findings on diagnostic imaging of other body structures
0.000 0.189 0.811
B99-B99 Other infectious diseases
0.000 0.190 0.810
M95.0 Acquired deformity of nose
0.000 0.190 0.810
L29.0 Pruritus ani
0.000 0.197 0.803
E53.8 Deficiency of other specified B group vitamins
0.000 0.197 0.803
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.000 0.199 0.801
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.200 0.800
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.200 0.800
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.201 0.799
R91 Abnormal findings on diagnostic imaging of lung
0.000 0.202 0.798
E14 Unspecified diabetes mellitus
0.000 0.202 0.798
I60 Subarachnoid haemorrhage
0.000 0.203 0.797
R49 Voice disturbances
0.000 0.210 0.790
I67 Other cerebrovascular diseases
0.000 0.211 0.789
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.214 0.786
L30 Other dermatitis
0.000 0.214 0.786
E10.5 With peripheral circulatory complications
0.000 0.216 0.784
I69 Sequelae of cerebrovascular disease
0.000 0.218 0.782
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.219 0.781
E66 Obesity
0.000 0.219 0.781
R47.1 Dysarthria and anarthria
0.000 0.222 0.778
B25 Cytomegaloviral disease
0.000 0.225 0.775
E10.2 With renal complications
0.000 0.228 0.772
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.231 0.769
I63 Cerebral infarction
0.000 0.234 0.766
E66.8 Other obesity
0.000 0.235 0.765
D86.9 Sarcoidosis, unspecified
0.000 0.235 0.765
C44.7 Skin of lower limb, including hip
0.000 0.236 0.764
H65-H75 Diseases of middle ear and mastoid
0.000 0.237 0.763
I20-I25 Ischaemic heart diseases
0.000 0.238 0.762
C44.2 Skin of ear and external auricular canal
0.000 0.238 0.762
M00-M03 Infectious arthropathies
0.000 0.238 0.762
C34 Malignant neoplasm of bronchus and lung
0.000 0.240 0.760
I67.8 Other specified cerebrovascular diseases
0.000 0.243 0.757
M34 Systemic sclerosis
0.000 0.243 0.757
M60-M63 Disorders of muscles
0.000 0.245 0.755
M22 Disorders of patella
0.000 0.247 0.753
M35.7 Hypermobility syndrome
0.000 0.247 0.753
A30-A49 Other bacterial diseases
0.000 0.248 0.752
D55-D59 Haemolytic anaemias
0.000 0.254 0.746
I21 Acute myocardial infarction
0.000 0.255 0.745
E55 Vitamin D deficiency
0.000 0.255 0.745
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.259 0.741
M46 Other inflammatory spondylopathies
0.000 0.260 0.740
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.260 0.740
H72 Perforation of tympanic membrane
0.000 0.261 0.739
E70-E90 Metabolic disorders
0.000 0.261 0.739
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.265 0.735
I62 Other nontraumatic intracranial haemorrhage
0.000 0.265 0.735
R41.2 Retrograde amnesia
0.000 0.267 0.733
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.269 0.731
Chapter XXII Codes for special purposes
0.000 0.270 0.730
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.000 0.272 0.728
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.276 0.724
I05-I09 Chronic rheumatic heart diseases
0.000 0.277 0.723
C34.9 Bronchus or lung, unspecified
0.000 0.279 0.721
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.000 0.279 0.721
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.280 0.720
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.282 0.718
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M12 Other specific arthropathies
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
C67 Malignant neoplasm of bladder
0.000 0.285 0.715
B37.0 Candidal stomatitis
0.000 0.285 0.715
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.287 0.713
L04 Acute lymphadenitis
0.000 0.289 0.711
L01 Impetigo
0.000 0.289 0.711
L00 Staphylococcal scalded skin syndrome
0.000 0.289 0.711
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.290 0.710
L58 Radiodermatitis
0.000 0.290 0.710
L55 Sunburn
0.000 0.290 0.710
I63.9 Cerebral infarction, unspecified
0.000 0.290 0.710
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.293 0.707
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.293 0.707
A75-A79 Rickettsioses
0.000 0.293 0.707
A70-A74 Other diseases caused by chlamydiae
0.000 0.293 0.707
A65-A69 Other spirochaetal diseases
0.000 0.293 0.707
A20-A28 Certain zoonotic bacterial diseases
0.000 0.293 0.707
A15-A19 Tuberculosis
0.000 0.293 0.707
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.294 0.706
L57.5 Actinic granuloma
0.000 0.294 0.706
L57.3 Poikiloderma of Civatte
0.000 0.294 0.706
L57.2 Cutis rhomboidalis nuchae
0.000 0.294 0.706
L57.1 Actinic reticuloid
0.000 0.294 0.706
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.295 0.705
R26.2 Difficulty in walking, not elsewhere classified
0.000 0.295 0.705
D86.0 Sarcoidosis of lung
0.000 0.296 0.704
R90 Abnormal findings on diagnostic imaging of central nervous system
0.000 0.296 0.704
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.297 0.703
B50-B64 Protozoal diseases
0.000 0.298 0.702
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.298 0.702
I69.3 Sequelae of cerebral infarction
0.000 0.299 0.701
D50.1 Sideropenic dysphagia
0.000 0.302 0.698
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.303 0.697
M07.6 Other enteropathic arthropathies
0.000 0.304 0.696
M07.5 Arthropathy in ulcerative colitis
0.000 0.304 0.696
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.304 0.696
M07.2 Psoriatic spondylitis
0.000 0.304 0.696
M07.1 Arthritis mutilans
0.000 0.304 0.696
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.304 0.696
L05 Pilonidal cyst
0.000 0.305 0.695
M14 Arthropathies in other diseases classified elsewhere
0.000 0.305 0.695
E13 Other specified diabetes mellitus
0.000 0.305 0.695
B33 Other viral diseases, not elsewhere classified
0.000 0.307 0.693
B30 Viral conjunctivitis
0.000 0.307 0.693
B27 Infectious mononucleosis
0.000 0.307 0.693
B26 Mumps
0.000 0.307 0.693
E40-E46 Malnutrition
0.000 0.307 0.692
L27 Dermatitis due to substances taken internally
0.000 0.308 0.692
R26.3 Immobility
0.000 0.308 0.692
H80-H83 Diseases of inner ear
0.000 0.309 0.691
A00-A09 Intestinal infectious diseases
0.000 0.311 0.689
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.311 0.689
L10-L14 Bullous disorders
0.000 0.311 0.689
I21.9 Acute myocardial infarction, unspecified
0.000 0.312 0.688
M11 Other crystal arthropathies
0.000 0.312 0.688
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.313 0.687
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.314 0.686
B99 Other and unspecified infectious diseases
0.000 0.316 0.684
E03.8 Other specified hypothyroidism
0.000 0.317 0.682
B35.1 Tinea unguium
0.000 0.318 0.681
M07.38 Other psoriatic arthropathies (Other)
0.000 0.319 0.681
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.319 0.681
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.319 0.681
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.319 0.681
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.319 0.681
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.319 0.681
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.319 0.681
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.319 0.681
B34.8 Other viral infections of unspecified site
0.000 0.321 0.679
B34.4 Papovirus infection, unspecified
0.000 0.321 0.679
B34.3 Parvovirus infection, unspecified
0.000 0.321 0.679
B34.2 Coronavirus infection, unspecified
0.000 0.321 0.679
B34.1 Enterovirus infection, unspecified
0.000 0.321 0.679
B34.0 Adenovirus infection, unspecified
0.000 0.321 0.679
L30.8 Other specified dermatitis
0.000 0.322 0.678
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.322 0.678
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.323 0.677
L08.1 Erythrasma
0.000 0.325 0.675
L08.0 Pyoderma
0.000 0.325 0.675
L29.9 Pruritus, unspecified
0.000 0.325 0.675
R49.0 Dysphonia
0.000 0.325 0.675
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.326 0.674
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.326 0.674
B48 Other mycoses, not elsewhere classified
0.000 0.328 0.672
B47 Mycetoma
0.000 0.328 0.672
B46 Zygomycosis
0.000 0.328 0.672
B45 Cryptococcosis
0.000 0.328 0.672
B43 Chromomycosis and phaeomycotic abscess
0.000 0.328 0.672
B42 Sporotrichosis
0.000 0.328 0.672
B41 Paracoccidioidomycosis
0.000 0.328 0.672
B40 Blastomycosis
0.000 0.328 0.672
B39 Histoplasmosis
0.000 0.328 0.672
B38 Coccidioidomycosis
0.000 0.328 0.672
B36 Other superficial mycoses
0.000 0.328 0.672
B65-B83 Helminthiases
0.000 0.328 0.671
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.328 0.671
R95-R99 Ill-defined and unknown causes of mortality
0.000 0.331 0.669
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.332 0.668
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.334 0.666
D64.8 Other specified anaemias
0.000 0.337 0.663
L24 Irritant contact dermatitis
0.000 0.337 0.662
L21 Seborrhoeic dermatitis
0.000 0.337 0.662
L26 Exfoliative dermatitis
0.000 0.337 0.662
L22 Diaper [napkin] dermatitis
0.000 0.337 0.662
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.338 0.662
M32 Systemic lupus erythematosus
0.000 0.338 0.662
E06.9 Thyroiditis, unspecified
0.000 0.338 0.662
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.339 0.661
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.339 0.661
M35.8 Other specified systemic involvement of connective tissue
0.000 0.339 0.661
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.339 0.661
M35.5 Multifocal fibrosclerosis
0.000 0.339 0.661
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.339 0.661
M35.2 Behcet's disease
0.000 0.339 0.661
M35.1 Other overlap syndromes
0.000 0.339 0.661
A80-A89 Viral infections of the central nervous system
0.000 0.339 0.661
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.339 0.660
E63 Other nutritional deficiencies
0.000 0.339 0.660
E56 Other vitamin deficiencies
0.000 0.339 0.660
E51 Thiamine deficiency
0.000 0.339 0.660
E50 Vitamin A deficiency
0.000 0.339 0.660
E60 Dietary zinc deficiency
0.000 0.339 0.660
E59 Dietary selenium deficiency
0.000 0.339 0.660
E58 Dietary calcium deficiency
0.000 0.339 0.660
E54 Ascorbic acid deficiency
0.000 0.339 0.660
E52 Niacin deficiency [pellagra]
0.000 0.339 0.660
C44.8 Overlapping lesion of skin
0.000 0.341 0.659
D61 Other aplastic anaemias
0.000 0.341 0.659
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.341 0.659
M06.3 Rheumatoid nodule
0.000 0.342 0.658
E10.6 With other specified complications
0.000 0.343 0.656
M31 Other necrotising vasculopathies
0.000 0.344 0.656
M30 Polyarteritis nodosa and related conditions
0.000 0.346 0.654
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.346 0.654
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.346 0.654
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.346 0.654
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.346 0.654
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.346 0.654
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.346 0.654
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.346 0.654
B37.7 Candidal septicaemia
0.000 0.346 0.653
B37.6 Candidal endocarditis
0.000 0.346 0.653
B37.5 Candidal meningitis
0.000 0.346 0.653
B37.2 Candidiasis of skin and nail
0.000 0.346 0.653
D64.4 Congenital dyserythropoietic anaemia
0.000 0.347 0.653
D64.3 Other sideroblastic anaemias
0.000 0.347 0.653
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.347 0.653
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.347 0.653
D64.0 Hereditary sideroblastic anaemia
0.000 0.347 0.653
H72.0 Central perforation of tympanic membrane
0.000 0.347 0.653
M23 Internal derangement of knee
0.000 0.347 0.653
B35.3 Tinea pedis
0.000 0.348 0.652
A41 Other septicaemia
0.000 0.348 0.652
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.349 0.651
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.000 0.350 0.650
E06.5 Other chronic thyroiditis
0.000 0.351 0.649
E06.4 Drug-induced thyroiditis
0.000 0.351 0.649
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.351 0.649
E06.1 Subacute thyroiditis
0.000 0.351 0.649
E06.0 Acute thyroiditis
0.000 0.351 0.649
E14.9 Without complications
0.000 0.351 0.649
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.352 0.648
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.000 0.355 0.645
L28 Lichen simplex chronicus and prurigo
0.000 0.359 0.641
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.359 0.641
R41.1 Anterograde amnesia
0.000 0.359 0.641
R87 Abnormal findings in specimens from female genital organs
0.000 0.359 0.641
D84 Other immunodeficiencies
0.000 0.361 0.639
D83 Common variable immunodeficiency
0.000 0.361 0.639
D82 Immunodeficiency associated with other major defects
0.000 0.361 0.639
D81 Combined immunodeficiencies
0.000 0.361 0.639
M99 Biomechanical lesions, not elsewhere classified
0.000 0.361 0.639
H60-H62 Diseases of external ear
0.000 0.361 0.638
L20 Atopic dermatitis
0.000 0.362 0.638
B25.9 Cytomegaloviral disease, unspecified
0.000 0.362 0.638
M34.9 Systemic sclerosis, unspecified
0.000 0.362 0.637
I05 Rheumatic mitral valve diseases
0.000 0.363 0.637
E20-E35 Disorders of other endocrine glands
0.000 0.363 0.637
E11 Non-insulin-dependent diabetes mellitus
0.000 0.364 0.636
L25 Unspecified contact dermatitis
0.000 0.365 0.634
C66 Malignant neoplasm of ureter
0.000 0.366 0.634
B37.1 Pulmonary candidiasis
0.000 0.366 0.634
C67.2 Lateral wall of bladder
0.000 0.367 0.633
R27 Other lack of coordination
0.000 0.367 0.633
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.368 0.632
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.368 0.632
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.368 0.632
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.368 0.632
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.368 0.632
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.368 0.632
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.368 0.632
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.368 0.632
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.368 0.632
M49 Spondylopathies in diseases classified elsewhere
0.000 0.368 0.632
M06.4 Inflammatory polyarthropathy
0.000 0.368 0.631
D53 Other nutritional anaemias
0.000 0.369 0.631
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.371 0.629
L57.4 Cutis laxa senilis
0.000 0.371 0.629
Chapter V Mental and behavioural disorders
0.000 0.372 0.628
M05.8 Other seropositive rheumatoid arthritis
0.000 0.372 0.628
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.372 0.628
M05.2 Rheumatoid vasculitis
0.000 0.372 0.628
M05.1 Rheumatoid lung disease
0.000 0.372 0.628
M05.0 Felty's syndrome
0.000 0.372 0.628
R49.8 Other and unspecified voice disturbances
0.000 0.374 0.626
I67.2 Cerebral atherosclerosis
0.000 0.374 0.626
D80 Immunodeficiency with predominantly antibody defects
0.000 0.375 0.625
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.376 0.624
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.376 0.624
I00-I02 Acute rheumatic fever
0.000 0.376 0.623
D52 Folate deficiency anaemia
0.000 0.377 0.623
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.000 0.377 0.623
B15-B19 Viral hepatitis
0.000 0.378 0.622
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.378 0.621
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.379 0.621
L23 Allergic contact dermatitis
0.000 0.381 0.619
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.381 0.619
M22.8 Other disorders of patella
0.000 0.381 0.619
E67 Other hyperalimentation
0.000 0.382 0.618
E68 Sequelae of hyperalimentation
0.000 0.382 0.618
E55.9 Vitamin D deficiency, unspecified
0.000 0.382 0.618
M80-M85 Disorders of bone density and structure
0.001 0.382 0.618
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.382 0.618
D50.8 Other iron deficiency anaemias
0.000 0.382 0.618
C65 Malignant neoplasm of renal pelvis
0.000 0.383 0.617
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.384 0.616
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.384 0.616
I73 Other peripheral vascular diseases
0.000 0.386 0.614
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.387 0.613
M33 Dermatopolymyositis
0.000 0.387 0.613
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.388 0.612
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.389 0.611
E53.9 Vitamin B deficiency, unspecified
0.000 0.389 0.611
E53.1 Pyridoxine deficiency
0.000 0.389 0.611
E53.0 Riboflavin deficiency
0.000 0.389 0.611
M23.3 Other meniscus derangements
0.000 0.389 0.611
C73 Malignant neoplasm of thyroid gland
0.000 0.389 0.611
E05.9 Thyrotoxicosis, unspecified
0.000 0.390 0.610
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.390 0.610
R26.1 Paralytic gait
0.000 0.391 0.609
L29.8 Other pruritus
0.000 0.392 0.608
L29.3 Anogenital pruritus, unspecified
0.000 0.392 0.608
L29.1 Pruritus scroti
0.000 0.392 0.608
E86 Volume depletion
0.000 0.392 0.608
E61 Deficiency of other nutrient elements
0.000 0.394 0.606
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.394 0.606
I77 Other disorders of arteries and arterioles
0.000 0.394 0.606
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.000 0.395 0.605
M95.8 Other specified acquired deformities of musculoskeletal system
0.000 0.395 0.605
M95.5 Acquired deformity of pelvis
0.000 0.395 0.605
M95.4 Acquired deformity of chest and rib
0.000 0.395 0.605
M95.3 Acquired deformity of neck
0.000 0.395 0.605
M95.2 Other acquired deformity of head
0.000 0.395 0.605
M95.1 Cauliflower ear
0.000 0.395 0.605
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.395 0.605
L50-L54 Urticaria and erythema
0.000 0.397 0.603
L42 Pityriasis rosea
0.000 0.397 0.603
E11.3 With ophthalmic complications
0.000 0.398 0.602
R87.6 Abnormal cytological findings
0.000 0.398 0.602
M62 Other disorders of muscle
0.000 0.399 0.601
H80 Otosclerosis
0.000 0.400 0.600
R46 Symptoms and signs involving appearance and behaviour
0.000 0.400 0.600
E27 Other disorders of adrenal gland
0.000 0.401 0.599
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.401 0.599
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.402 0.598
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.402 0.598
M91-M94 Chondropathies
0.000 0.403 0.596
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.404 0.596
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.404 0.596
D86.3 Sarcoidosis of skin
0.000 0.404 0.596
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.404 0.596
D86.1 Sarcoidosis of lymph nodes
0.000 0.404 0.596
R26.0 Ataxic gait
0.000 0.405 0.595
R43 Disturbances of smell and taste
0.000 0.407 0.593
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.408 0.592
M00 Pyogenic arthritis
0.000 0.409 0.591
M22.3 Other derangements of patella
0.000 0.410 0.590
H65 Nonsuppurative otitis media
0.000 0.411 0.589
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.412 0.588
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.413 0.587
C79 Secondary malignant neoplasm of other sites
0.000 0.413 0.587
I73.0 Raynaud's syndrome
0.000 0.413 0.587
H73 Other disorders of tympanic membrane
0.000 0.413 0.587
C34.1 Upper lobe, bronchus or lung
0.000 0.414 0.586
A41.9 Septicaemia, unspecified
0.000 0.416 0.584
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.416 0.584
C34.3 Lower lobe, bronchus or lung
0.000 0.416 0.584
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.416 0.583
B37.4 Candidiasis of other urogenital sites
0.000 0.418 0.582
A08 Viral and other specified intestinal infections
0.000 0.418 0.582
B35.9 Dermatophytosis, unspecified
0.000 0.418 0.582
B35.8 Other dermatophytoses
0.000 0.418 0.582
B35.6 Tinea cruris
0.000 0.418 0.582
B35.5 Tinea imbricata
0.000 0.418 0.582
B35.4 Tinea corporis
0.000 0.418 0.582
B35.2 Tinea manuum
0.000 0.418 0.582
B35.0 Tinea barbae and tinea capitis
0.000 0.418 0.582
L30.9 Dermatitis, unspecified
0.000 0.418 0.582
R93.6 Abnormal findings on diagnostic imaging of limbs
0.000 0.418 0.582
D62 Acute posthaemorrhagic anaemia
0.000 0.418 0.582
D59 Acquired haemolytic anaemia
0.000 0.419 0.581
R44 Other symptoms and signs involving general sensations and perceptions
0.000 0.419 0.581
M23.4 Loose body in knee
0.000 0.419 0.581
I08 Multiple valve diseases
0.000 0.419 0.581
R90.0 Intracranial space-occupying lesion
0.000 0.420 0.580
A02 Other Salmonella infections
0.000 0.421 0.579
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.421 0.579
E66.0 Obesity due to excess calories
0.000 0.422 0.578
I22 Subsequent myocardial infarction
0.000 0.423 0.577
M80 Osteoporosis with pathological fracture
0.000 0.423 0.577
E14.3 With ophthalmic complications
0.000 0.423 0.577
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.423 0.577
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.000 0.423 0.577
D51 Vitamin B12 deficiency anaemia
0.000 0.423 0.576
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.423 0.577
B37.3 Candidiasis of vulva and vagina
0.000 0.425 0.575
M10 Gout
0.000 0.426 0.574

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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