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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2516518
log Bayes Factor = 13.8223
Chromosome 6   position 31,435,119  (GRCh37) Explore rs2516518 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.003 0.997
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.005 0.995
L40-L45 Papulosquamous disorders
0.000 0.008 0.992
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.010 0.990
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.023 0.977
E10.3 With ophthalmic complications
0.000 0.028 0.972
L20-L30 Dermatitis and eczema
0.000 0.031 0.969
E65-E68 Obesity and other hyperalimentation
0.000 0.031 0.969
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.032 0.968
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.041 0.959
M06 Other rheumatoid arthritis
0.000 0.047 0.953
E66 Obesity
0.000 0.048 0.952
E10.1 With ketoacidosis
0.000 0.050 0.950
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.050 0.950
E66.8 Other obesity
0.000 0.051 0.949
L29 Pruritus
0.000 0.052 0.948
L57.0 Actinic keratosis
0.000 0.054 0.946
E14 Unspecified diabetes mellitus
0.000 0.058 0.942
L29.0 Pruritus ani
0.000 0.081 0.919
E06 Thyroiditis
0.000 0.082 0.918
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.084 0.916
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.099 0.901
E10.4 With neurological complications
0.000 0.107 0.893
L08 Other local infections of skin and subcutaneous tissue
0.000 0.110 0.890
E14.9 Without complications
0.000 0.113 0.887
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.118 0.882
M06.0 Seronegative rheumatoid arthritis
0.000 0.121 0.879
E05.9 Thyrotoxicosis, unspecified
0.000 0.124 0.876
M05-M14 Inflammatory polyarthropathies
0.000 0.133 0.867
E06.3 Autoimmune thyroiditis
0.000 0.145 0.855
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.151 0.849
E50-E64 Other nutritional deficiencies
0.000 0.165 0.835
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.165 0.835
E10.5 With peripheral circulatory complications
0.000 0.168 0.832
M07 Psoriatic and enteropathic arthropathies
0.000 0.178 0.822
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.191 0.809
L30 Other dermatitis
0.000 0.193 0.807
L29.9 Pruritus, unspecified
0.000 0.194 0.806
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.201 0.799
E10.2 With renal complications
0.000 0.202 0.798
L40.0 Psoriasis vulgaris
0.000 0.203 0.797
# Top node
0.000 0.205 0.795
Chapter I Certain infectious and parasitic diseases
0.000 0.208 0.792
M07.3 Other psoriatic arthropathies
0.000 0.210 0.790
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.220 0.780
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.221 0.779
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.227 0.773
B25-B34 Other viral diseases
0.000 0.231 0.769
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.238 0.762
E14.3 With ophthalmic complications
0.000 0.240 0.760
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.245 0.755
E66.0 Obesity due to excess calories
0.000 0.248 0.752
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.249 0.751
B34 Viral infection of unspecified site
0.000 0.250 0.750
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.253 0.747
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.256 0.744
L40.8 Other psoriasis
0.000 0.257 0.743
E10.0 With coma
0.000 0.258 0.742
B35-B49 Mycoses
0.000 0.258 0.742
E53 Deficiency of other B group vitamins
0.000 0.258 0.742
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.259 0.741
L21 Seborrhoeic dermatitis
0.000 0.259 0.741
M35.3 Polymyalgia rheumatica
0.000 0.269 0.731
M35 Other systemic involvement of connective tissue
0.000 0.271 0.729
L28 Lichen simplex chronicus and prurigo
0.000 0.274 0.726
B37 Candidiasis
0.000 0.275 0.725
B34.9 Viral infection, unspecified
0.000 0.277 0.723
L29.8 Other pruritus
0.000 0.277 0.723
M20-M25 Other joint disorders
0.000 0.279 0.721
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
L30.8 Other specified dermatitis
0.000 0.284 0.716
B37.8 Candidiasis of other sites
0.000 0.288 0.712
L44 Other papulosquamous disorders
0.000 0.288 0.711
L41 Parapsoriasis
0.000 0.288 0.711
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.288 0.711
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.296 0.704
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.299 0.700
L58 Radiodermatitis
0.000 0.299 0.700
L55 Sunburn
0.000 0.299 0.700
E10.8 With unspecified complications
0.000 0.300 0.700
E11 Non-insulin-dependent diabetes mellitus
0.000 0.300 0.700
A30-A49 Other bacterial diseases
0.000 0.300 0.700
D80-D89 Certain disorders involving the immune mechanism
0.000 0.304 0.696
E20-E35 Disorders of other endocrine glands
0.001 0.305 0.695
L24 Irritant contact dermatitis
0.000 0.305 0.695
L26 Exfoliative dermatitis
0.000 0.305 0.695
L22 Diaper [napkin] dermatitis
0.000 0.305 0.695
E67 Other hyperalimentation
0.000 0.305 0.695
E68 Sequelae of hyperalimentation
0.000 0.305 0.695
L27 Dermatitis due to substances taken internally
0.000 0.306 0.694
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.306 0.694
L57.5 Actinic granuloma
0.000 0.306 0.694
L57.3 Poikiloderma of Civatte
0.000 0.306 0.694
L57.2 Cutis rhomboidalis nuchae
0.000 0.306 0.694
L57.1 Actinic reticuloid
0.000 0.306 0.694
E04 Other non-toxic goitre
0.000 0.309 0.691
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.309 0.691
E27 Other disorders of adrenal gland
0.000 0.313 0.687
L10-L14 Bullous disorders
0.000 0.313 0.687
M06.8 Other specified rheumatoid arthritis
0.000 0.317 0.683
M06.2 Rheumatoid bursitis
0.000 0.317 0.683
M06.1 Adult-onset Still's disease
0.000 0.317 0.683
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.317 0.683
E66.1 Drug-induced obesity
0.000 0.317 0.683
E05.5 Thyroid crisis or storm
0.000 0.319 0.681
E05.4 Thyrotoxicosis factitia
0.000 0.319 0.681
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.319 0.681
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.319 0.681
E06.9 Thyroiditis, unspecified
0.000 0.320 0.680
L29.3 Anogenital pruritus, unspecified
0.000 0.320 0.679
L29.1 Pruritus scroti
0.000 0.320 0.679
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.324 0.676
E14.8 With unspecified complications
0.000 0.324 0.675
E14.7 With multiple complications
0.000 0.324 0.675
E14.6 With other specified complications
0.000 0.324 0.675
E14.5 With peripheral circulatory complications
0.000 0.324 0.675
E14.2 Withrenal complications
0.000 0.324 0.675
E14.1 With ketoacidosis
0.000 0.324 0.675
E14.0 With coma
0.000 0.324 0.675
E53.8 Deficiency of other specified B group vitamins
0.000 0.324 0.676
E03.8 Other specified hypothyroidism
0.000 0.326 0.674
B99-B99 Other infectious diseases
0.000 0.330 0.670
L25 Unspecified contact dermatitis
0.000 0.330 0.670
M14 Arthropathies in other diseases classified elsewhere
0.000 0.331 0.669
E27.1 Primary adrenocortical insufficiency
0.000 0.336 0.664
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.337 0.663
E40-E46 Malnutrition
0.000 0.339 0.661
E11.3 With ophthalmic complications
0.000 0.340 0.660
E06.5 Other chronic thyroiditis
0.000 0.341 0.658
E06.4 Drug-induced thyroiditis
0.000 0.341 0.658
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.341 0.658
E06.1 Subacute thyroiditis
0.000 0.341 0.658
E06.0 Acute thyroiditis
0.000 0.341 0.658
L04 Acute lymphadenitis
0.000 0.343 0.657
L01 Impetigo
0.000 0.343 0.657
L00 Staphylococcal scalded skin syndrome
0.000 0.343 0.657
A00-A09 Intestinal infectious diseases
0.000 0.350 0.650
E14.4 With neurological complications
0.000 0.352 0.648
D86 Sarcoidosis
0.000 0.354 0.646
B34.8 Other viral infections of unspecified site
0.000 0.357 0.643
M06.4 Inflammatory polyarthropathy
0.000 0.360 0.640
L08.1 Erythrasma
0.000 0.362 0.638
L08.0 Pyoderma
0.000 0.362 0.638
E13 Other specified diabetes mellitus
0.000 0.362 0.638
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.362 0.638
D60-D64 Aplastic and other anaemias
0.000 0.363 0.637
B37.0 Candidal stomatitis
0.000 0.364 0.636
M06.3 Rheumatoid nodule
0.000 0.365 0.635
D55-D59 Haemolytic anaemias
0.000 0.366 0.634
L20 Atopic dermatitis
0.000 0.366 0.634
A41 Other septicaemia
0.000 0.366 0.634
E55 Vitamin D deficiency
0.000 0.368 0.632
M45-M49 Spondylopathies
0.000 0.368 0.632
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.368 0.631
L23 Allergic contact dermatitis
0.000 0.369 0.631
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.370 0.630
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.370 0.630
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.370 0.630
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.370 0.630
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.370 0.630
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.370 0.630
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.370 0.630
L29.2 Pruritus vulvae
0.000 0.375 0.625
M12 Other specific arthropathies
0.000 0.378 0.622
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.378 0.622
M08 Juvenile arthritis
0.000 0.378 0.622
M35.7 Hypermobility syndrome
0.000 0.380 0.620
M34 Systemic sclerosis
0.000 0.382 0.618
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.385 0.615
D50-D53 Nutritional anaemias
0.000 0.386 0.614
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.386 0.614
M45 Ankylosing spondylitis
0.000 0.388 0.612
R26 Abnormalities of gait and mobility
0.000 0.390 0.610
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.000 0.391 0.609
M31 Other necrotising vasculopathies
0.000 0.391 0.609
D86.9 Sarcoidosis, unspecified
0.000 0.392 0.608
E65 Localised adiposity
0.000 0.393 0.607
E03.1 Congenital hypothyroidism without goitre
0.000 0.393 0.607
M35.0 Sicca syndrome [Sjogren]
0.000 0.398 0.602
L57.4 Cutis laxa senilis
0.000 0.398 0.602
D64 Other anaemias
0.000 0.400 0.599
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.401 0.598
E63 Other nutritional deficiencies
0.000 0.401 0.598
E56 Other vitamin deficiencies
0.000 0.401 0.598
E51 Thiamine deficiency
0.000 0.401 0.598
E50 Vitamin A deficiency
0.000 0.401 0.598
E60 Dietary zinc deficiency
0.000 0.401 0.598
E59 Dietary selenium deficiency
0.000 0.401 0.598
E58 Dietary calcium deficiency
0.000 0.401 0.598
E54 Ascorbic acid deficiency
0.000 0.401 0.598
E52 Niacin deficiency [pellagra]
0.000 0.401 0.598
B50-B64 Protozoal diseases
0.000 0.405 0.595
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.407 0.593
L50-L54 Urticaria and erythema
0.000 0.408 0.592
M07.6 Other enteropathic arthropathies
0.000 0.411 0.589
M07.5 Arthropathy in ulcerative colitis
0.000 0.411 0.589
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.411 0.589
M07.2 Psoriatic spondylitis
0.000 0.411 0.589
M07.1 Arthritis mutilans
0.000 0.411 0.589
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.411 0.589
B25 Cytomegaloviral disease
0.000 0.414 0.586
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.417 0.583
B99 Other and unspecified infectious diseases
0.000 0.417 0.583
R47-R49 Symptoms and signs involving speech and voice
0.000 0.418 0.582
L42 Pityriasis rosea
0.000 0.418 0.581
E11.5 With peripheral circulatory complications
0.000 0.418 0.582
M05 Seropositive rheumatoid arthritis
0.000 0.419 0.581
L30.5 Pityriasis alba
0.000 0.421 0.578
L30.4 Erythema intertrigo
0.000 0.421 0.578
L30.3 Infective dermatitis
0.000 0.421 0.578
L30.2 Cutaneous autosensitisation
0.000 0.421 0.578
L30.1 Dyshidrosis [pompholyx]
0.000 0.421 0.578
L30.0 Nummular dermatitis
0.000 0.421 0.578
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.422 0.578
R26.8 Other and unspecified abnormalities of gait and mobility
0.000 0.424 0.576
A41.8 Other specified septicaemia
0.000 0.425 0.575
D73 Diseases of spleen
0.000 0.425 0.575
D64.9 Anaemia, unspecified
0.000 0.425 0.575
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.426 0.574
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.427 0.573
R26.2 Difficulty in walking, not elsewhere classified
0.000 0.427 0.573
B35 Dermatophytosis
0.000 0.429 0.571
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.430 0.570
L05 Pilonidal cyst
0.000 0.431 0.569
R27 Other lack of coordination
0.000 0.431 0.569
M60-M63 Disorders of muscles
0.000 0.432 0.568
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.432 0.568
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.432 0.568
A75-A79 Rickettsioses
0.000 0.432 0.568
A70-A74 Other diseases caused by chlamydiae
0.000 0.432 0.568
A65-A69 Other spirochaetal diseases
0.000 0.432 0.568
A20-A28 Certain zoonotic bacterial diseases
0.000 0.432 0.568
M07.38 Other psoriatic arthropathies (Other)
0.000 0.434 0.566
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.434 0.566
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.434 0.566
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.434 0.566
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.434 0.566
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.434 0.566
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.434 0.566
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.434 0.566
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.436 0.564
L28.0 Lichen simplex chronicus
0.000 0.437 0.563
R47 Speech disturbances, not elsewhere classified
0.000 0.439 0.561
A02 Other Salmonella infections
0.000 0.440 0.560
B37.1 Pulmonary candidiasis
0.000 0.441 0.559
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.443 0.557
M31.3 Wegener's granulomatosis
0.000 0.444 0.556
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.445 0.555
L60-L75 Disorders of skin appendages
0.000 0.448 0.552
B33 Other viral diseases, not elsewhere classified
0.000 0.448 0.552
B30 Viral conjunctivitis
0.000 0.448 0.552
B26 Mumps
0.000 0.448 0.552
A15-A19 Tuberculosis
0.000 0.449 0.551
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.449 0.550
B27 Infectious mononucleosis
0.000 0.450 0.550
A40 Streptococcal septicaemia
0.000 0.450 0.550
E07 Other disorders of thyroid
0.000 0.451 0.549
A04 Other bacterial intestinal infections
0.000 0.451 0.549
R47.0 Dysphasia and aphasia
0.000 0.451 0.549
E05.8 Other thyrotoxicosis
0.000 0.453 0.547
A41.9 Septicaemia, unspecified
0.000 0.453 0.547
E04.0 Non-toxic diffuse goitre
0.000 0.454 0.546
A49 Bacterial infection of unspecified site
0.000 0.454 0.546
E11.1 With ketoacidosis
0.000 0.455 0.545
M34.9 Systemic sclerosis, unspecified
0.000 0.456 0.544
R27.0 Ataxia, unspecified
0.000 0.458 0.542
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.458 0.542
M22 Disorders of patella
0.000 0.458 0.542
M00-M03 Infectious arthropathies
0.000 0.460 0.539
B34.3 Parvovirus infection, unspecified
0.000 0.462 0.538
B34.2 Coronavirus infection, unspecified
0.000 0.462 0.538
B34.1 Enterovirus infection, unspecified
0.000 0.462 0.538
B34.0 Adenovirus infection, unspecified
0.000 0.462 0.538
R26.3 Immobility
0.000 0.463 0.537
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.464 0.536
B34.4 Papovirus infection, unspecified
0.000 0.464 0.536
E27.8 Other specified disorders of adrenal gland
0.000 0.465 0.535
B48 Other mycoses, not elsewhere classified
0.000 0.468 0.532
B47 Mycetoma
0.000 0.468 0.532
B46 Zygomycosis
0.000 0.468 0.532
B45 Cryptococcosis
0.000 0.468 0.532
B43 Chromomycosis and phaeomycotic abscess
0.000 0.468 0.532
B42 Sporotrichosis
0.000 0.468 0.532
B41 Paracoccidioidomycosis
0.000 0.468 0.532
B40 Blastomycosis
0.000 0.468 0.532
B39 Histoplasmosis
0.000 0.468 0.532
B38 Coccidioidomycosis
0.000 0.468 0.532
E53.9 Vitamin B deficiency, unspecified
0.000 0.468 0.532
E53.1 Pyridoxine deficiency
0.000 0.468 0.532
E53.0 Riboflavin deficiency
0.000 0.468 0.532
M11 Other crystal arthropathies
0.000 0.468 0.532
D50 Iron deficiency anaemia
0.000 0.468 0.532
L21.8 Other seborrhoeic dermatitis
0.000 0.469 0.531
L21.1 Seborrhoeic infantile dermatitis
0.000 0.469 0.531
L21.0 Seborrhoea capitis
0.000 0.469 0.531
B65-B83 Helminthiases
0.000 0.469 0.530
D59 Acquired haemolytic anaemia
0.000 0.469 0.530
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.470 0.530
M14.6 Neuropathic arthropathy
0.000 0.473 0.527
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.473 0.526
L43 Lichen planus
0.000 0.477 0.523
D73.0 Hyposplenism
0.000 0.477 0.523
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.477 0.523
M35.8 Other specified systemic involvement of connective tissue
0.000 0.477 0.523
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.477 0.523
M35.5 Multifocal fibrosclerosis
0.000 0.477 0.523
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.477 0.523
M35.2 Behcet's disease
0.000 0.477 0.523
M35.1 Other overlap syndromes
0.000 0.477 0.523
B37.4 Candidiasis of other urogenital sites
0.000 0.477 0.523
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.479 0.521
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.479 0.521
L28.2 Other prurigo
0.000 0.479 0.520
B37.7 Candidal septicaemia
0.000 0.480 0.520
B37.6 Candidal endocarditis
0.000 0.480 0.520
B37.5 Candidal meningitis
0.000 0.480 0.520
B37.2 Candidiasis of skin and nail
0.000 0.480 0.520
E04.1 Non-toxic single thyroid nodule
0.000 0.480 0.520
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.480 0.520
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.483 0.517
M32 Systemic lupus erythematosus
0.000 0.483 0.517
L30.9 Dermatitis, unspecified
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
D50.9 Iron deficiency anaemia, unspecified
0.000 0.486 0.514
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.000 0.487 0.513
L41.9 Parapsoriasis, unspecified
0.000 0.490 0.510
L41.8 Other parapsoriasis
0.000 0.490 0.510
L41.5 Retiform parapsoriasis
0.000 0.490 0.510
L41.4 Large plaque parapsoriasis
0.000 0.490 0.510
L41.3 Small plaque parapsoriasis
0.000 0.490 0.510
L41.2 Lymphomatoid papulosis
0.000 0.490 0.510
L41.1 Pityriasis lichenoides chronica
0.000 0.490 0.510
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.490 0.510
L44.9 Papulosquamous disorder, unspecified
0.000 0.490 0.510
L44.8 Other specified papulosquamous disorders
0.000 0.490 0.510
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.490 0.510
L44.3 Lichen ruber moniliformis
0.000 0.490 0.510
L44.2 Lichen striatus
0.000 0.490 0.510
L44.1 Lichen nitidus
0.000 0.490 0.510
L44.0 Pityriasis rubra pilaris
0.000 0.490 0.510
E11.8 With unspecified complications
0.000 0.490 0.510
L28.1 Prurigo nodularis
0.000 0.494 0.506
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.495 0.505
L56.4 Polymorphous light eruption
0.000 0.495 0.505
L56.3 Solar urticaria
0.000 0.495 0.505
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.495 0.505
L56.1 Drug photoallergic response
0.000 0.495 0.505
L56.0 Drug phototoxic response
0.000 0.495 0.505
A04.7 Enterocolitis due to Clostridium difficile
0.000 0.495 0.505
M46 Other inflammatory spondylopathies
0.000 0.496 0.504
B36 Other superficial mycoses
0.000 0.497 0.503
L55.9 Sunburn, unspecified
0.000 0.498 0.502
L55.8 Other sunburn
0.000 0.498 0.502
L55.2 Sunburn of third degree
0.000 0.498 0.502
L55.1 Sunburn of second degree
0.000 0.498 0.502
L55.0 Sunburn of first degree
0.000 0.498 0.502
L58.9 Radiodermatitis, unspecified
0.000 0.498 0.502
L58.1 Chronic radiodermatitis
0.000 0.498 0.502
L58.0 Acute radiodermatitis
0.000 0.498 0.502
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.498 0.502
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.498 0.502
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.498 0.502
E11.7 With multiple complications
0.000 0.498 0.502
A44 Bartonellosis
0.000 0.498 0.502
A43 Nocardiosis
0.000 0.498 0.502
A42 Actinomycosis
0.000 0.498 0.502
A39 Meningococcal infection
0.000 0.498 0.502
A37 Whooping cough
0.000 0.498 0.502
A36 Diphtheria
0.000 0.498 0.502
A32 Listeriosis
0.000 0.498 0.502
A31 Infection due to other mycobacteria
0.000 0.498 0.502
A30 Leprosy [Hansen's disease]
0.000 0.498 0.502
A38 Scarlet fever
0.000 0.498 0.502
A35 Other tetanus
0.000 0.498 0.502
A34 Obstetrical tetanus
0.000 0.498 0.502
A33 Tetanus neonatorum
0.000 0.498 0.502
E26 Hyperaldosteronism
0.000 0.499 0.501
D70 Agranulocytosis
0.000 0.499 0.501
E11.2 With renal complications
0.000 0.500 0.500
D84 Other immunodeficiencies
0.000 0.501 0.499
D83 Common variable immunodeficiency
0.000 0.501 0.499
D82 Immunodeficiency associated with other major defects
0.000 0.501 0.499
D81 Combined immunodeficiencies
0.000 0.501 0.499
D86.0 Sarcoidosis of lung
0.000 0.501 0.499
E35 Disorders of endocrine glands in diseases classified elsewhere
0.001 0.501 0.498
E32 Diseases of thymus
0.001 0.501 0.498
E31 Polyglandular dysfunction
0.001 0.501 0.498
E30 Disorders of puberty, not elsewhere classified
0.001 0.501 0.498
E25 Adrenogenital disorders
0.001 0.501 0.498
L24.9 Irritant contact dermatitis, unspecified cause
0.000 0.502 0.498
L24.8 Irritant contact dermatitis due to other agents
0.000 0.502 0.498
L24.7 Irritant contact dermatitis due to plants, except food
0.000 0.502 0.498
L24.6 Irritant contact dermatitis due to food in contact with the skin
0.000 0.502 0.498
L24.5 Irritant contact dermatitis due to other chemical products
0.000 0.502 0.498
L24.4 Irritant contact dermatitis due to drugs in contact with the skin
0.000 0.502 0.498
L24.3 Irritant contact dermatitis due to cosmetics
0.000 0.502 0.498
L24.2 Irritant contact dermatitis due to solvents
0.000 0.502 0.498
L24.1 Irritant contact dermatitis due to oils and greases
0.000 0.502 0.498
L24.0 Irritant contact dermatitis due to detergents
0.000 0.502 0.498
E67.8 Other specified hyperalimentation
0.000 0.502 0.498
E67.3 Hypervitaminosis D
0.000 0.502 0.498
E67.2 Megavitamin-B6 syndrome
0.000 0.502 0.498
E67.1 Hypercarotenaemia
0.000 0.502 0.498
E67.0 Hypervitaminosis A
0.000 0.502 0.498
A41.0 Septicaemia due to Staphylococcus aureus
0.000 0.502 0.498
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.502 0.498
L27.8 Dermatitis due to other substances taken internally
0.000 0.502 0.498
L27.2 Dermatitis due to ingested food
0.000 0.502 0.498
D72 Other disorders of white blood cells
0.000 0.503 0.497
E04.8 Other specified non-toxic goitre
0.000 0.504 0.496
A02.0 Salmonella gastro-enteritis
0.000 0.505 0.495
D62 Acute posthaemorrhagic anaemia
0.000 0.507 0.493
E27.5 Adrenomedullary hyperfunction
0.000 0.507 0.493
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.507 0.493
E27.2 Addisonian crisis
0.000 0.507 0.493
E27.0 Other adrenocortical overactivity
0.000 0.507 0.493
L12 Pemphigoid
0.000 0.507 0.492
L11 Other acantholytic disorders
0.000 0.507 0.492
L10 Pemphigus
0.000 0.507 0.492
L14 Bullous disorders in diseases classified elsewhere
0.000 0.507 0.492
E11.6 With other specified complications
0.000 0.508 0.492
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.510 0.490
M06.18 Adult-onset Still's disease (Other)
0.000 0.510 0.490
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.510 0.490
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.510 0.490
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.510 0.490
M06.14 Adult-onset Still's disease (Hand)
0.000 0.510 0.490
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.510 0.490
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.510 0.490
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.510 0.490
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.510 0.490
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.510 0.490
M06.28 Rheumatoid bursitis (Other)
0.000 0.510 0.490
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.510 0.490
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.510 0.490
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.510 0.490
M06.24 Rheumatoid bursitis (Hand)
0.000 0.510 0.490
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.510 0.490
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.510 0.490
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.510 0.490
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.510 0.490
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.510 0.490
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.510 0.490
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.510 0.490
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.510 0.490
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.510 0.490
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.510 0.490
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.510 0.490
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.510 0.490
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.510 0.490
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.510 0.490
E20 Hypoparathyroidism
0.001 0.510 0.489
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.511 0.489
Chapter XXII Codes for special purposes
0.000 0.511 0.489
M30 Polyarteritis nodosa and related conditions
0.000 0.512 0.487
E55.9 Vitamin D deficiency, unspecified
0.000 0.513 0.487
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.514 0.486
E22 Hyperfunction of pituitary gland
0.000 0.515 0.484

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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