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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2517425
log Bayes Factor = 183.674
Chromosome 6   position 30,949,670  (GRCh37) Explore rs2517425 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10.3 With ophthalmic complications
0.999 0.001 0.000
K90 Intestinal malabsorption
0.998 0.002 0.000
K74 Fibrosis and cirrhosis of liver
0.998 0.002 0.000
K74.3 Primary biliary cirrhosis
0.998 0.002 0.000
E50-E64 Other nutritional deficiencies
0.998 0.002 0.000
M35.0 Sicca syndrome [Sjogren]
0.997 0.003 0.000
K70-K77 Diseases of liver
0.996 0.004 0.000
M35 Other systemic involvement of connective tissue
0.990 0.010 0.000
E14 Unspecified diabetes mellitus
0.987 0.013 0.000
Chapter XI Diseases of the digestive system
0.986 0.014 0.000
K90-K93 Other diseases of the digestive system
0.986 0.014 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.985 0.015 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.984 0.016 0.000
M20-M25 Other joint disorders
0.983 0.017 0.000
E61 Deficiency of other nutrient elements
0.983 0.017 0.000
# Top node
0.983 0.017 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.982 0.018 0.000
E14.3 With ophthalmic complications
0.977 0.023 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.977 0.023 0.000
E06 Thyroiditis
0.977 0.023 0.000
E10.2 With renal complications
0.977 0.023 0.000
K75 Other inflammatory liver diseases
0.973 0.027 0.000
E07 Other disorders of thyroid
0.971 0.029 0.000
K75.4 Autoimmune hepatitis
0.967 0.033 0.000
C81 Hodgkin's disease
0.965 0.035 0.000
E61.1 Iron deficiency
0.965 0.035 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.964 0.036 0.000
K74.6 Other and unspecified cirrhosis of liver
0.964 0.036 0.000
C85.1 B-cell lymphoma, unspecified
0.959 0.041 0.000
L50-L54 Urticaria and erythema
0.956 0.044 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.950 0.050 0.000
E06.3 Autoimmune thyroiditis
0.949 0.051 0.000
K50-K52 Noninfective enteritis and colitis
0.946 0.054 0.000
E10.1 With ketoacidosis
0.946 0.054 0.000
E07.9 Disorder of thyroid, unspecified
0.946 0.054 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.945 0.055 0.000
K52 Other non-infective gastro-enteritis and colitis
0.944 0.056 0.000
E53 Deficiency of other B group vitamins
0.938 0.062 0.000
K72 Hepatic failure, not elsewhere classified
0.932 0.068 0.000
K74.5 Biliary cirrhosis, unspecified
0.924 0.076 0.000
Chapter VII Diseases of the eye and adnexa
0.924 0.076 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.922 0.078 0.000
C81.9 Hodgkin's disease, unspecified
0.921 0.079 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.918 0.082 0.000
K90.9 Intestinal malabsorption, unspecified
0.909 0.091 0.000
M34 Systemic sclerosis
0.907 0.093 0.000
M24 Other specific joint derangements
0.904 0.096 0.000
L50 Urticaria
0.901 0.099 0.000
E53.8 Deficiency of other specified B group vitamins
0.887 0.113 0.000
H53-H54 Visual disturbances and blindness
0.883 0.117 0.000
M60-M63 Disorders of muscles
0.883 0.117 0.000
C83.1 Small cleaved cell (diffuse)
0.880 0.120 0.000
L53 Other erythematous conditions
0.875 0.125 0.000
M32 Systemic lupus erythematosus
0.874 0.126 0.000
C83.3 Large cell (diffuse)
0.874 0.126 0.000
D80-D89 Certain disorders involving the immune mechanism
0.871 0.129 0.000
L10-L14 Bullous disorders
0.869 0.131 0.000
K52.3 Indeterminate colitis
0.863 0.137 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.863 0.137 0.000
C92 Myeloid leukaemia
0.862 0.138 0.000
E14.8 With unspecified complications
0.859 0.141 0.000
K72.9 Hepatic failure, unspecified
0.855 0.145 0.000
H54 Blindness and low vision
0.853 0.147 0.000
H54.9 Unspecified visual impairment (binocular)
0.848 0.152 0.000
L52 Erythema nodosum
0.838 0.162 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.837 0.163 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.836 0.164 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.832 0.168 0.000
E10.4 With neurological complications
0.824 0.176 0.000
C81.2 Mixed cellularity
0.824 0.176 0.000
H05 Disorders of orbit
0.823 0.177 0.000
M35.2 Behcet's disease
0.822 0.178 0.000
M35.7 Hypermobility syndrome
0.822 0.178 0.000
E61.2 Magnesium deficiency
0.821 0.178 0.000
C88 Malignant immunoproliferative diseases
0.817 0.183 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.812 0.188 0.000
C81.0 Lymphocytic predominance
0.812 0.188 0.000
L50.9 Urticaria, unspecified
0.811 0.189 0.000
L53.8 Other specified erythematous conditions
0.809 0.191 0.000
M35.1 Other overlap syndromes
0.807 0.193 0.000
E03.8 Other specified hypothyroidism
0.806 0.194 0.000
M45-M49 Spondylopathies
0.806 0.194 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.804 0.196 0.000
C92.1 Chronic myeloid leukaemia
0.803 0.197 0.000
M40-M43 Deforming dorsopathies
0.801 0.199 0.000
E55 Vitamin D deficiency
0.800 0.199 0.000
E51 Thiamine deficiency
0.800 0.200 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.799 0.201 0.000
L13 Other bullous disorders
0.799 0.201 0.000
E10.8 With unspecified complications
0.798 0.202 0.000
E06.9 Thyroiditis, unspecified
0.796 0.204 0.000
H05.0 Acute inflammation of orbit
0.794 0.206 0.000
M21 Other acquired deformities of limbs
0.793 0.207 0.000
L50.1 Idiopathic urticaria
0.791 0.209 0.000
M45 Ankylosing spondylitis
0.788 0.212 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.785 0.215 0.000
D60-D64 Aplastic and other anaemias
0.785 0.215 0.000
M24.1 Other articular cartilage disorders
0.782 0.218 0.000
M62 Other disorders of muscle
0.782 0.218 0.000
M34.1 CR(E)ST syndrome
0.781 0.219 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.777 0.223 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.772 0.228 0.000
D55-D59 Haemolytic anaemias
0.772 0.228 0.000
C83.0 Small cell (diffuse)
0.771 0.229 0.000
M34.9 Systemic sclerosis, unspecified
0.767 0.233 0.000
K72.1 Chronic hepatic failure
0.764 0.236 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.764 0.236 0.000
E14.5 With peripheral circulatory complications
0.760 0.240 0.000
D61 Other aplastic anaemias
0.758 0.242 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.757 0.243 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.756 0.244 0.000
L53.0 Toxic erythema
0.753 0.247 0.000
K73 Chronic hepatitis, not elsewhere classified
0.751 0.249 0.000
K52.1 Toxic gastro-enteritis and colitis
0.751 0.249 0.000
M00-M03 Infectious arthropathies
0.749 0.251 0.000
L13.0 Dermatitis herpetiformis
0.748 0.252 0.000
E10.7 With multiple complications
0.746 0.253 0.000
D83 Common variable immunodeficiency
0.745 0.255 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.743 0.257 0.000
C81.1 Nodular sclerosis
0.743 0.257 0.000
H30-H36 Disorders of choroid and retina
0.740 0.260 0.000
E14.6 With other specified complications
0.739 0.261 0.000
M24.7 Protrusio acetabuli
0.738 0.262 0.000
D80 Immunodeficiency with predominantly antibody defects
0.738 0.262 0.000
E07.8 Other specified disorders of thyroid
0.737 0.263 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.737 0.263 0.000
E14.2 Withrenal complications
0.736 0.264 0.000
D61.9 Aplastic anaemia, unspecified
0.735 0.265 0.000
H36 Retinal disorders in diseases classified elsewhere
0.729 0.271 0.000
L51 Erythema multiforme
0.728 0.272 0.000
H05.2 Exophthalmic conditions
0.726 0.274 0.000
E06.5 Other chronic thyroiditis
0.725 0.275 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.725 0.275 0.000
C84.0 Mycosis fungoides
0.724 0.276 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.724 0.276 0.000
K75.9 Inflammatory liver disease, unspecified
0.723 0.277 0.000
H36.0 Diabetic retinopathy
0.723 0.277 0.000
C93 Monocytic leukaemia
0.722 0.277 0.000
M33 Dermatopolymyositis
0.722 0.278 0.000
E53.9 Vitamin B deficiency, unspecified
0.722 0.278 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.722 0.278 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.721 0.279 0.000
E16 Other disorders of pancreatic internal secretion
0.720 0.280 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.719 0.281 0.000
Chapter V Mental and behavioural disorders
0.719 0.281 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.716 0.284 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.716 0.284 0.000
K90.1 Tropical sprue
0.716 0.284 0.000
K74.4 Secondary biliary cirrhosis
0.716 0.284 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.716 0.284 0.000
K74.1 Hepatic sclerosis
0.716 0.284 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.715 0.285 0.000
E63 Other nutritional deficiencies
0.715 0.285 0.000
E50 Vitamin A deficiency
0.715 0.285 0.000
E60 Dietary zinc deficiency
0.715 0.285 0.000
E59 Dietary selenium deficiency
0.715 0.285 0.000
E54 Ascorbic acid deficiency
0.715 0.285 0.000
E52 Niacin deficiency [pellagra]
0.715 0.285 0.000
M60 Myositis
0.715 0.285 0.000
K77 Liver disorders in diseases classified elsewhere
0.714 0.286 0.000
C95 Leukaemia of unspecified cell type
0.714 0.286 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.710 0.290 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.710 0.290 0.000
M35.5 Multifocal fibrosclerosis
0.710 0.290 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.710 0.290 0.000
M22 Disorders of patella
0.708 0.292 0.000
E14.7 With multiple complications
0.708 0.292 0.000
E14.0 With coma
0.708 0.292 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.707 0.293 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.707 0.293 0.000
H20 Iridocyclitis
0.707 0.293 0.000
E58 Dietary calcium deficiency
0.706 0.293 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.706 0.293 0.000
C85.0 Lymphosarcoma
0.706 0.293 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.706 0.294 0.000
E14.1 With ketoacidosis
0.706 0.294 0.000
H21 Other disorders of iris and ciliary body
0.705 0.295 0.000
E61.9 Deficiency of nutrient element, unspecified
0.705 0.295 0.000
E61.8 Deficiency of other specified nutrient elements
0.705 0.295 0.000
E61.7 Deficiency of multiple nutrient elements
0.705 0.295 0.000
E61.6 Vanadium deficiency
0.705 0.295 0.000
E61.5 Molybdenum deficiency
0.705 0.295 0.000
E61.4 Chromium deficiency
0.705 0.295 0.000
E61.3 Manganese deficiency
0.705 0.295 0.000
E61.0 Copper deficiency
0.705 0.295 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.705 0.295 0.000
M24.9 Joint derangement, unspecified
0.704 0.296 0.000
M62.8 Other specified disorders of muscle
0.704 0.296 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.704 0.296 0.000
C94 Other leukaemias of specified cell type
0.704 0.296 0.000
C86 Other specified types of T/NK-cell lymphoma
0.704 0.296 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.703 0.297 0.000
M30 Polyarteritis nodosa and related conditions
0.702 0.298 0.000
M21.8 Other specified acquired deformities of limbs
0.701 0.299 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.701 0.299 0.000
E06.4 Drug-induced thyroiditis
0.700 0.300 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.700 0.300 0.000
E06.1 Subacute thyroiditis
0.700 0.300 0.000
E06.0 Acute thyroiditis
0.700 0.300 0.000
H06.2 Dysthyroid exophthalmos
0.699 0.301 0.000
C83.7 Burkitt's tumour
0.699 0.301 0.000
L08 Other local infections of skin and subcutaneous tissue
0.698 0.302 0.000
K75.2 Nonspecific reactive hepatitis
0.697 0.303 0.000
K75.1 Phlebitis of portal vein
0.697 0.303 0.000
K90.8 Other intestinal malabsorption
0.696 0.304 0.000
E07.1 Dyshormogenetic goitre
0.696 0.304 0.000
E07.0 Hypersecretion of calcitonin
0.696 0.304 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.692 0.308 0.000
E56 Other vitamin deficiencies
0.692 0.308 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.692 0.308 0.000
C81.3 Lymphocytic depletion
0.692 0.308 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.690 0.310 0.000
M21.6 Other acquired deformities of ankle and foot
0.689 0.311 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.687 0.313 0.000
K72.0 Acute and subacute hepatic failure
0.687 0.313 0.000
L54 Erythema in diseases classified elsewhere
0.685 0.315 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.685 0.315 0.000
K75.8 Other specified inflammatory liver diseases
0.684 0.316 0.000
M43 Other deforming dorsopathies
0.684 0.316 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.684 0.316 0.000
C83.6 Undifferentiated (diffuse)
0.681 0.319 0.000
C83.5 Lymphoblastic (diffuse)
0.681 0.319 0.000
C83.4 Immunoblastic (diffuse)
0.681 0.319 0.000
C83.2 Mixed small and large cell (diffuse)
0.681 0.319 0.000
M34.8 Other forms of systemic sclerosis
0.681 0.319 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.680 0.320 0.000
K71 Toxic liver disease
0.678 0.322 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.678 0.322 0.000
F45 Somatoform disorders
0.677 0.323 0.000
C84.5 Other and unspecified T-cell lymphomas
0.675 0.324 0.000
L12 Pemphigoid
0.674 0.326 0.000
M34.0 Progressive systemic sclerosis
0.673 0.327 0.000
E53.1 Pyridoxine deficiency
0.673 0.327 0.000
E53.0 Riboflavin deficiency
0.673 0.327 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.672 0.327 0.000
L94 Other localised connective tissue disorders
0.672 0.328 0.000
M35.8 Other specified systemic involvement of connective tissue
0.671 0.328 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.669 0.331 0.000
L93 Lupus erythematosus
0.669 0.331 0.000
M40 Kyphosis and lordosis
0.667 0.333 0.000
F45.8 Other somatoform disorders
0.662 0.338 0.000
E40-E46 Malnutrition
0.661 0.339 0.000
E55.9 Vitamin D deficiency, unspecified
0.659 0.341 0.000
M24.2 Disorder of ligament
0.658 0.342 0.000
E51.2 Wernicke's encephalopathy
0.658 0.342 0.000
D84 Other immunodeficiencies
0.658 0.342 0.000
M32.8 Other forms of systemic lupus erythematosus
0.655 0.345 0.000
M43.0 Spondylolysis
0.655 0.345 0.000
D83.9 Common variable immunodeficiency, unspecified
0.654 0.346 0.000
E14.4 With neurological complications
0.654 0.346 0.000
M05-M14 Inflammatory polyarthropathies
0.654 0.346 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.653 0.347 0.000
C81.7 Other Hodgkin's disease
0.652 0.348 0.000
M24.0 Loose body in joint
0.652 0.348 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.650 0.350 0.000
L50.0 Allergic urticaria
0.648 0.352 0.000
L50.6 Contact urticaria
0.646 0.354 0.000
L50.5 Cholinergic urticaria
0.646 0.354 0.000
L50.4 Vibratory urticaria
0.646 0.354 0.000
L50.3 Dermatographic urticaria
0.646 0.354 0.000
L50.2 Urticaria due to cold and heat
0.646 0.354 0.000
H53 Visual disturbances
0.645 0.355 0.000
H21.0 Hyphaema
0.641 0.359 0.000
M02 Reactive arthropathies
0.640 0.360 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.639 0.361 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.639 0.361 0.000
D59 Acquired haemolytic anaemia
0.639 0.361 0.000
L50.8 Other urticaria
0.638 0.362 0.000
H05.4 Enophthalmos
0.638 0.362 0.000
M43.02 Spondylolysis (Cervical region)
0.638 0.362 0.000
M24.6 Ankylosis of joint
0.637 0.363 0.000
F60-F69 Disorders of adult personality and behaviour
0.634 0.366 0.000
L51.9 Erythema multiforme, unspecified
0.633 0.367 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.633 0.367 0.000
M61 Calcification and ossification of muscle
0.633 0.367 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.633 0.367 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.631 0.369 0.000
E13 Other specified diabetes mellitus
0.631 0.369 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.631 0.369 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.630 0.370 0.000
E05.8 Other thyrotoxicosis
0.630 0.370 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.629 0.371 0.000
H55-H59 Other disorders of eye and adnexa
0.629 0.371 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.629 0.371 0.000
M91-M94 Chondropathies
0.629 0.371 0.000
L53.3 Other chronic figurate erythema
0.628 0.372 0.000
L53.2 Erythema marginatum
0.628 0.372 0.000
L53.1 Erythema annulare centrifugum
0.628 0.372 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.627 0.373 0.000
L94.2 Calcinosis cutis
0.627 0.373 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.626 0.373 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.626 0.373 0.000
H05.8 Other disorders of orbit
0.625 0.375 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.625 0.375 0.000
D81 Combined immunodeficiencies
0.624 0.376 0.000
L10 Pemphigus
0.623 0.376 0.000
L14 Bullous disorders in diseases classified elsewhere
0.623 0.376 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.622 0.378 0.000
L83 Acanthosis nigricans
0.622 0.378 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.619 0.381 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.619 0.381 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.619 0.381 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.619 0.381 0.000
C84.3 Lymphoepithelioid lymphoma
0.619 0.381 0.000
C84.2 T-zone lymphoma
0.619 0.381 0.000
C84.1 Sezary's diease
0.619 0.381 0.000
C92.9 Myeloid leukaemia, unspecified
0.618 0.382 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.618 0.382 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.618 0.382 0.000
C92.5 Acute myelomonocytic leukaemia
0.618 0.382 0.000
C92.3 Myeloid sarcoma
0.618 0.382 0.000
C92.2 Subacute myeloid leukaemia
0.618 0.382 0.000
D58 Other hereditary haemolytic anaemias
0.618 0.382 0.000
H20.8 Other iridocyclitis
0.617 0.383 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.615 0.385 0.000
D82 Immunodeficiency associated with other major defects
0.615 0.385 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.615 0.385 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.614 0.386 0.000
L03 Cellulitis
0.614 0.386 0.000
H54.3 Unqualified visual loss, both eyes
0.612 0.388 0.000
H54.1 Blindness, one eye, low vision, other eye
0.612 0.388 0.000
L93.0 Discoid lupus erythematosus
0.611 0.389 0.000
H34 Retinal vascular occlusions
0.610 0.390 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.609 0.391 0.000
H54.5 Low vision, one eye
0.606 0.394 0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.605 0.395 0.000
E16.2 Hypoglycaemia, unspecified
0.604 0.396 0.000
L03.0 Cellulitis of finger and toe
0.603 0.397 0.000
D89.1 Cryoglobulinaemia
0.603 0.397 0.000
M15-M19 Arthrosis
0.603 0.397 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.601 0.399 0.000
E15 Nondiabetic hypoglycaemic coma
0.600 0.400 0.000
M07 Psoriatic and enteropathic arthropathies
0.600 0.400 0.000
C92.7 Other myeloid leukaemia
0.599 0.401 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.598 0.402 0.000
D86 Sarcoidosis
0.598 0.402 0.000
H54.7 Unspecified visual loss
0.598 0.402 0.000
H54.0 Blindness, both eyes
0.597 0.403 0.000
M11 Other crystal arthropathies
0.597 0.403 0.000
L00 Staphylococcal scalded skin syndrome
0.596 0.403 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.595 0.405 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.595 0.405 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.595 0.405 0.000
H21.2 Degeneration of iris and ciliary body
0.595 0.405 0.000
M21.1 Varus deformity, not elsewhere classified
0.593 0.406 0.000
E10.0 With coma
0.593 0.407 0.000
D61.1 Drug-induced aplastic anaemia
0.593 0.407 0.000
H20.9 Iridocyclitis, unspecified
0.592 0.408 0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.590 0.410 0.000
H05.3 Deformity of orbit
0.590 0.410 0.000
H05.1 Chronic inflammatory disorders of orbit
0.590 0.410 0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.589 0.411 0.000
H43-H45 Disorders of vitreous body and globe
0.588 0.412 0.000
M22.3 Other derangements of patella
0.587 0.413 0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)
0.587 0.413 0.000
M33.1 Other dermatomyositis
0.586 0.414 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.586 0.414 0.000
C88.7 Other malignant immunoproliferative diseases
0.586 0.414 0.000
C88.3 Immunoproliferative small intestinal disease
0.586 0.414 0.000
C88.2 Gamma heavy chain disease
0.586 0.414 0.000
C88.1 Alpha heavy chain disease
0.586 0.414 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.585 0.415 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.584 0.416 0.000
H54.2 Low vision, both eyes
0.584 0.416 0.000
F45.0 Somatisation disorder
0.584 0.416 0.000
C92.4 Acute promyelocytic leukaemia
0.583 0.417 0.000
M46 Other inflammatory spondylopathies
0.582 0.418 0.000
M60.9 Myositis, unspecified
0.580 0.419 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.578 0.422 0.000
C92.0 Acute myeloid leukaemia
0.578 0.422 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.577 0.423 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.576 0.424 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.576 0.424 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.576 0.424 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.576 0.424 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.576 0.424 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.576 0.424 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.576 0.424 0.000
F44 Dissociative [conversion] disorders
0.576 0.424 0.000
L92.0 Granuloma annulare
0.576 0.424 0.000
M22.9 Disorder of patella, unspecified
0.575 0.425 0.000
M42 Spinal osteochondrosis
0.575 0.425 0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified
0.574 0.426 0.000
E55.0 Rickets, active
0.574 0.426 0.000
E51.9 Thiamine deficiency, unspecified
0.573 0.426 0.000
E51.8 Other manifestations of thiamine deficiency
0.573 0.426 0.000
E51.1 Beriberi
0.573 0.426 0.000
L11 Other acantholytic disorders
0.573 0.427 0.000
L13.9 Bullous disorder, unspecified
0.573 0.427 0.000
L13.8 Other specified bullous disorders
0.573 0.427 0.000
L13.1 Subcorneal pustular dermatitis
0.573 0.427 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.572 0.428 0.000
H46 Optic neuritis
0.572 0.428 0.000
M24.02 Loose body in joint (Upper arm)
0.571 0.429 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.571 0.429 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.571 0.429 0.000
L80 Vitiligo
0.570 0.430 0.000
H18 Other disorders of cornea
0.569 0.431 0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)
0.569 0.431 0.000
M21.7 Unequal limb length (acquired)
0.567 0.432 0.000
L01 Impetigo
0.567 0.433 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.567 0.433 0.000
L95.8 Other vasculitis limited to skin
0.565 0.435 0.000
F60 Specific personality disorders
0.565 0.435 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.565 0.435 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.565 0.435 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.565 0.435 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.565 0.435 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.565 0.435 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.565 0.435 0.000
M21.9 Acquired deformity of limb, unspecified
0.564 0.436 0.000
F45.3 Somatoform autonomic dysfunction
0.564 0.436 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.563 0.437 0.000
M07.3 Other psoriatic arthropathies
0.562 0.438 0.000
H54.6 Unqualified visual loss, one eye
0.561 0.439 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.561 0.439 0.000
M24.18 Other articular cartilage disorders (Other)
0.561 0.439 0.000
M24.14 Other articular cartilage disorders (Hand)
0.561 0.439 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.561 0.439 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.561 0.439 0.000
M31 Other necrotising vasculopathies
0.561 0.439 0.000
M62.9 Disorder of muscle, unspecified
0.561 0.439 0.000
M62.4 Contracture of muscle
0.561 0.439 0.000
M62.3 Immobility syndrome (paraplegic)
0.561 0.439 0.000
M62.2 Ischaemic infarction of muscle
0.561 0.439 0.000
M24.96 Joint derangement, unspecified (Lower leg)
0.561 0.439 0.000
M62.0 Diastasis of muscle
0.561 0.439 0.000
M30.0 Polyarteritis nodosa
0.560 0.439 0.000
H53.1 Subjective visual disturbances
0.560 0.440 0.000
C82.4 Follicular lymphoma grade IIIb
0.559 0.441 0.000
M62.84 Other specified disorders of muscle (Hand)
0.558 0.441 0.000
M21.4 Flat foot [pes planus] (acquired)
0.558 0.442 0.000
M11.2 Other chondrocalcinosis
0.557 0.443 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.556 0.443 0.000
M15 Polyarthrosis
0.555 0.445 0.000
M49 Spondylopathies in diseases classified elsewhere
0.555 0.445 0.000
D57 Sickle-cell disorders
0.554 0.446 0.000
D55 Anaemia due to enzyme disorders
0.554 0.446 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.554 0.446 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.553 0.447 0.000
E10.5 With peripheral circulatory complications
0.550 0.449 0.000
M22.2 Patellofemoral disorders
0.549 0.451 0.000
H05.9 Disorder of orbit, unspecified
0.548 0.452 0.000
L05 Pilonidal cyst
0.548 0.452 0.000
M40.5 Lordosis, unspecified
0.547 0.453 0.000
M24.66 Ankylosis of joint (Lower leg)
0.546 0.454 0.000
M02.3 Reiter's disease
0.546 0.454 0.000
M21.0 Valgus deformity, not elsewhere classified
0.546 0.454 0.000
F99-F99 Unspecified mental disorder
0.545 0.455 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.544 0.456 0.000
D61.8 Other specified aplastic anaemias
0.543 0.457 0.000
D61.3 Idiopathic aplastic anaemia
0.543 0.457 0.000
D61.2 Aplastic anaemia due to other external agents
0.543 0.457 0.000
H06.3 Other disorders of orbit in diseases classified elsewhere
0.542 0.458 0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.542 0.458 0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.542 0.458 0.000
D64 Other anaemias
0.542 0.458 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.542 0.458 0.000
L81 Other disorders of pigmentation
0.541 0.459 0.000
H10-H13 Disorders of conjunctiva
0.540 0.460 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.540 0.460 0.000
H53.9 Visual disturbance, unspecified
0.540 0.460 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.538 0.461 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.538 0.461 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.538 0.462 0.000
C95.9 Leukaemia, unspecified
0.538 0.462 0.000
H30 Chorioretinal inflammation
0.538 0.462 0.000
F80-F89 Disorders of psychological development
0.537 0.463 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.537 0.463 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.537 0.463 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.537 0.463 0.000
C93.1 Chronic monocytic leukaemia
0.537 0.463 0.000
E10.6 With other specified complications
0.536 0.464 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.536 0.464 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.536 0.464 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.536 0.464 0.000
C84.4 Peripheral T-cell lymphoma
0.536 0.464 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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