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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523557
log Bayes Factor = 89.8237
Chromosome 6   position 31,331,257  (GRCh37) Explore rs2523557 on Ensembl!
Variant rs2523557 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
M07.3 Other psoriatic arthropathies
1.000 0.000 0.000
M45 Ankylosing spondylitis
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
M07 Psoriatic and enteropathic arthropathies
1.000 0.000 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.999 0.001 0.000
E14 Unspecified diabetes mellitus
0.999 0.001 0.000
M45-M49 Spondylopathies
0.999 0.001 0.000
L40-L45 Papulosquamous disorders
0.998 0.002 0.000
# Top node
0.998 0.002 0.000
E10.1 With ketoacidosis
0.998 0.002 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.998 0.002 0.000
M35 Other systemic involvement of connective tissue
0.997 0.003 0.000
E11.9 Without complications
0.997 0.003 0.000
M24 Other specific joint derangements
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.992 0.008 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.992 0.008 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.991 0.009 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.990 0.010 0.000
F30-F39 Mood [affective] disorders
0.988 0.012 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.987 0.013 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.984 0.016 0.000
F31 Bipolar affective disorder
0.981 0.019 0.000
E10.4 With neurological complications
0.980 0.020 0.000
E10.2 With renal complications
0.976 0.024 0.000
E14.9 Without complications
0.976 0.024 0.000
E06 Thyroiditis
0.973 0.027 0.000
E65-E68 Obesity and other hyperalimentation
0.972 0.028 0.000
E16 Other disorders of pancreatic internal secretion
0.972 0.028 0.000
M25 Other joint disorders, not elsewhere classified
0.971 0.029 0.000
E70-E90 Metabolic disorders
0.968 0.032 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.966 0.034 0.000
E20-E35 Disorders of other endocrine glands
0.966 0.034 0.000
M24.0 Loose body in joint
0.966 0.034 0.000
M35.3 Polymyalgia rheumatica
0.965 0.035 0.000
M35.0 Sicca syndrome [Sjogren]
0.964 0.036 0.000
E16.2 Hypoglycaemia, unspecified
0.961 0.039 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.961 0.039 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.960 0.040 0.000
E78.0 Pure hypercholesterolaemia
0.960 0.040 0.000
D80-D89 Certain disorders involving the immune mechanism
0.956 0.044 0.000
D86 Sarcoidosis
0.952 0.048 0.000
E66 Obesity
0.947 0.053 0.000
E14.3 With ophthalmic complications
0.946 0.054 0.000
M24.2 Disorder of ligament
0.944 0.056 0.000
L43 Lichen planus
0.944 0.056 0.000
M25.9 Joint disorder, unspecified
0.943 0.057 0.000
M25.5 Pain in joint
0.943 0.057 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.942 0.058 0.000
F80-F89 Disorders of psychological development
0.941 0.059 0.000
F30 Manic episode
0.940 0.060 0.000
E66.8 Other obesity
0.934 0.066 0.000
M25.56 Pain in joint (Lower leg)
0.930 0.070 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.928 0.072 0.000
D60-D64 Aplastic and other anaemias
0.927 0.073 0.000
M60-M63 Disorders of muscles
0.927 0.073 0.000
E14.8 With unspecified complications
0.927 0.073 0.000
D86.0 Sarcoidosis of lung
0.925 0.075 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.925 0.075 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.923 0.077 0.000
M34 Systemic sclerosis
0.916 0.084 0.000
M05 Seropositive rheumatoid arthritis
0.915 0.085 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.911 0.088 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.911 0.089 0.000
E11.3 With ophthalmic complications
0.908 0.092 0.000
E78.2 Mixed hyperlipidaemia
0.907 0.093 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.907 0.093 0.000
E11.1 With ketoacidosis
0.904 0.096 0.000
E10.5 With peripheral circulatory complications
0.899 0.101 0.000
D61 Other aplastic anaemias
0.890 0.110 0.000
E10.8 With unspecified complications
0.890 0.110 0.000
E11.5 With peripheral circulatory complications
0.889 0.111 0.000
F80 Specific developmental disorders of speech and language
0.882 0.118 0.000
E06.3 Autoimmune thyroiditis
0.879 0.121 0.000
M62 Other disorders of muscle
0.878 0.122 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.873 0.127 0.000
E06.9 Thyroiditis, unspecified
0.872 0.128 0.000
F30.0 Hypomania
0.872 0.128 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.869 0.131 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.869 0.131 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.868 0.132 0.000
Chapter VIII Diseases of the ear and mastoid process
0.862 0.138 0.000
E21.3 Hyperparathyroidism, unspecified
0.862 0.138 0.000
M80-M85 Disorders of bone density and structure
0.857 0.143 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.857 0.143 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.856 0.144 0.000
M24.02 Loose body in joint (Upper arm)
0.855 0.145 0.000
D61.9 Aplastic anaemia, unspecified
0.854 0.146 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.853 0.147 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.853 0.147 0.000
L43.9 Lichen planus, unspecified
0.852 0.148 0.000
M25.59 Pain in joint (Site unspecified)
0.851 0.149 0.000
D55-D59 Haemolytic anaemias
0.850 0.150 0.000
E85 Amyloidosis
0.849 0.151 0.000
N00-N08 Glomerular diseases
0.848 0.152 0.000
M33 Dermatopolymyositis
0.848 0.152 0.000
E10.7 With multiple complications
0.847 0.153 0.000
D64 Other anaemias
0.846 0.154 0.000
M62.8 Other specified disorders of muscle
0.845 0.155 0.000
L40.4 Guttate psoriasis
0.843 0.157 0.000
D86.1 Sarcoidosis of lymph nodes
0.840 0.160 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.839 0.161 0.000
M34.1 CR(E)ST syndrome
0.836 0.164 0.000
N03 Chronic nephritic syndrome
0.835 0.165 0.000
F80.1 Expressive language disorder
0.833 0.167 0.000
E50-E64 Other nutritional deficiencies
0.833 0.167 0.000
E14.1 With ketoacidosis
0.832 0.168 0.000
L40.1 Generalised pustular psoriasis
0.831 0.169 0.000
E89.3 Postprocedural hypopituitarism
0.829 0.171 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.827 0.173 0.000
H60-H62 Diseases of external ear
0.826 0.174 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.825 0.175 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.825 0.175 0.000
N04 Nephrotic syndrome
0.824 0.176 0.000
M06.8 Other specified rheumatoid arthritis
0.823 0.177 0.000
M32 Systemic lupus erythematosus
0.821 0.179 0.000
L43.8 Other lichen planus
0.818 0.182 0.000
K90 Intestinal malabsorption
0.818 0.182 0.000
M91-M94 Chondropathies
0.817 0.183 0.000
D75 Other diseases of blood and blood-forming organs
0.816 0.184 0.000
F30.9 Manic episode, unspecified
0.813 0.187 0.000
E11.2 With renal complications
0.813 0.187 0.000
M24.1 Other articular cartilage disorders
0.812 0.188 0.000
E23 Hypofunction and other disorders of pituitary gland
0.811 0.189 0.000
F60-F69 Disorders of adult personality and behaviour
0.811 0.189 0.000
E66.0 Obesity due to excess calories
0.810 0.190 0.000
M06.3 Rheumatoid nodule
0.810 0.190 0.000
H60 Otitis externa
0.810 0.190 0.000
M35.1 Other overlap syndromes
0.809 0.191 0.000
L40.8 Other psoriasis
0.809 0.191 0.000
M35.2 Behcet's disease
0.807 0.193 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.807 0.193 0.000
M24.28 Disorder of ligament (Other)
0.806 0.193 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.806 0.194 0.000
H36.0 Diabetic retinopathy
0.806 0.194 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.802 0.198 0.000
L41 Parapsoriasis
0.802 0.198 0.000
E11.7 With multiple complications
0.801 0.199 0.000
F34 Persistent mood [affective] disorders
0.800 0.200 0.000
E11.0 With coma
0.799 0.201 0.000
M35.7 Hypermobility syndrome
0.798 0.202 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.797 0.203 0.000
M82 Osteoporosis in diseases classified elsewhere
0.797 0.203 0.000
D86.8 Sarcoidosis of other and combined sites
0.797 0.203 0.000
M49 Spondylopathies in diseases classified elsewhere
0.796 0.204 0.000
L40.0 Psoriasis vulgaris
0.796 0.204 0.000
M24.01 Loose body in joint (Shoulder region)
0.795 0.205 0.000
N03.9 Unspecified
0.795 0.205 0.000
E89.1 Postprocedural hypoinsulinaemia
0.794 0.206 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.793 0.207 0.000
E85.4 Organ-limited amyloidosis
0.791 0.209 0.000
E25 Adrenogenital disorders
0.791 0.209 0.000
M25.50 Pain in joint (Multiple sites)
0.788 0.212 0.000
E06.1 Subacute thyroiditis
0.786 0.214 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.786 0.214 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.783 0.217 0.000
M24.7 Protrusio acetabuli
0.783 0.217 0.000
N05 Unspecified nephritic syndrome
0.782 0.218 0.000
D86.9 Sarcoidosis, unspecified
0.782 0.218 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.781 0.219 0.000
M24.07 Loose body in joint (Ankle and foot)
0.781 0.219 0.000
M00-M03 Infectious arthropathies
0.780 0.219 0.000
E74 Other disorders of carbohydrate metabolism
0.779 0.221 0.000
E11.6 With other specified complications
0.779 0.221 0.000
D64.9 Anaemia, unspecified
0.779 0.221 0.000
M80 Osteoporosis with pathological fracture
0.778 0.222 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.777 0.223 0.000
E78.1 Pure hyperglyceridaemia
0.775 0.225 0.000
M11 Other crystal arthropathies
0.774 0.226 0.000
E26 Hyperaldosteronism
0.774 0.226 0.000
E78.8 Other disorders of lipoprotein metabolism
0.771 0.229 0.000
M24.04 Loose body in joint (Hand)
0.770 0.230 0.000
E78.6 Lipoprotein deficiency
0.768 0.232 0.000
D73 Diseases of spleen
0.767 0.233 0.000
M25.4 Effusion of joint
0.766 0.234 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.766 0.234 0.000
D75.1 Secondary polycythaemia
0.762 0.238 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.760 0.240 0.000
F38 Other mood [affective] disorders
0.759 0.241 0.000
E24 Cushing's syndrome
0.758 0.242 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.758 0.242 0.000
E23.7 Disorder of pituitary gland, unspecified
0.758 0.242 0.000
H65-H75 Diseases of middle ear and mastoid
0.757 0.243 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.756 0.244 0.000
E65 Localised adiposity
0.755 0.245 0.000
M82.1 Osteoporosis in endocrine disorders
0.754 0.246 0.000
M25.93 Joint disorder, unspecified (Forearm)
0.752 0.248 0.000
E14.4 With neurological complications
0.752 0.248 0.000
E27 Other disorders of adrenal gland
0.751 0.249 0.000
E06.5 Other chronic thyroiditis
0.749 0.251 0.000
M25.53 Pain in joint (Forearm)
0.748 0.252 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.747 0.253 0.000
H60.1 Cellulitis of external ear
0.745 0.255 0.000
M24.26 Disorder of ligament (Lower leg)
0.744 0.256 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.744 0.256 0.000
M24.9 Joint derangement, unspecified
0.744 0.256 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.743 0.257 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.743 0.257 0.000
Chapter XIV Diseases of the genitourinary system
0.743 0.257 0.000
H60.3 Other infective otitis externa
0.743 0.257 0.000
N04.9 Unspecified
0.742 0.258 0.000
N04.1 Focal and segmental glomerular lesions
0.742 0.258 0.000
F99-F99 Unspecified mental disorder
0.741 0.259 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.741 0.259 0.000
F81 Specific developmental disorders of scholastic skills
0.740 0.259 0.000
M25.90 Joint disorder, unspecified (Multiple sites)
0.740 0.260 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.740 0.260 0.000
M24.23 Disorder of ligament (Forearm)
0.739 0.261 0.000
F60 Specific personality disorders
0.738 0.262 0.000
E11.4 With neurological complications
0.737 0.263 0.000
M33.1 Other dermatomyositis
0.737 0.263 0.000
E61 Deficiency of other nutrient elements
0.735 0.265 0.000
E22 Hyperfunction of pituitary gland
0.734 0.265 0.000
E79 Disorders of purine and pyrimidine metabolism
0.734 0.266 0.000
D61.1 Drug-induced aplastic anaemia
0.734 0.266 0.000
F70-F79 Mental retardation
0.733 0.267 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.731 0.269 0.000
E89.0 Postprocedural hypothyroidism
0.731 0.269 0.000
M24.03 Loose body in joint (Forearm)
0.730 0.270 0.000
N05.1 Focal and segmental glomerular lesions
0.728 0.272 0.000
D56 Thalassaemia
0.728 0.272 0.000
H65 Nonsuppurative otitis media
0.727 0.273 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.727 0.273 0.000
M25.94 Joint disorder, unspecified (Hand)
0.726 0.274 0.000
M08 Juvenile arthritis
0.725 0.275 0.000
F31.8 Other bipolar affective disorders
0.720 0.279 0.000
E14.5 With peripheral circulatory complications
0.720 0.280 0.000
M24.6 Ankylosis of joint
0.720 0.280 0.000
M24.5 Contracture of joint
0.719 0.281 0.000
F84 Pervasive developmental disorders
0.719 0.281 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.717 0.283 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.717 0.283 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.717 0.283 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.717 0.283 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.717 0.283 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.717 0.283 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.717 0.283 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
M07.5 Arthropathy in ulcerative colitis
0.717 0.283 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.717 0.283 0.000
M07.2 Psoriatic spondylitis
0.717 0.283 0.000
M07.1 Arthritis mutilans
0.717 0.283 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E14.7 With multiple complications
0.716 0.284 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.716 0.284 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.715 0.285 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.715 0.285 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.715 0.285 0.000
M35.5 Multifocal fibrosclerosis
0.715 0.285 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.715 0.285 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.715 0.285 0.000
E14.2 Withrenal complications
0.715 0.285 0.000
M34.0 Progressive systemic sclerosis
0.712 0.288 0.000
N05.2 Diffuse membranous glomerulonephritis
0.712 0.288 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.711 0.289 0.000
N17-N19 Renal failure
0.711 0.289 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.710 0.290 0.000
N18 Chronic renal failure
0.709 0.291 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.709 0.291 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.708 0.291 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.708 0.292 0.000
D82 Immunodeficiency associated with other major defects
0.708 0.292 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.707 0.293 0.000
E21.4 Other specified disorders of parathyroid gland
0.707 0.293 0.000
M25.92 Joint disorder, unspecified (Upper arm)
0.707 0.293 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.706 0.294 0.000
M05.1 Rheumatoid lung disease
0.706 0.294 0.000
E15 Nondiabetic hypoglycaemic coma
0.705 0.295 0.000
M25.57 Pain in joint (Ankle and foot)
0.704 0.296 0.000
L43.0 Hypertrophic lichen planus
0.702 0.298 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.702 0.298 0.000
M24.06 Loose body in joint-Lower leg
0.701 0.299 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.701 0.299 0.000
D86.3 Sarcoidosis of skin
0.700 0.300 0.000
E10.0 With coma
0.699 0.301 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.698 0.302 0.000
E06.4 Drug-induced thyroiditis
0.698 0.302 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.698 0.302 0.000
E06.0 Acute thyroiditis
0.698 0.302 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.698 0.302 0.000
L40.3 Pustulosis palmaris et plantaris
0.697 0.303 0.000
E67 Other hyperalimentation
0.697 0.303 0.000
E68 Sequelae of hyperalimentation
0.697 0.303 0.000
E21.2 Other hyperparathyroidism
0.697 0.303 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.697 0.303 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.697 0.303 0.000
E16.4 Abnormal secretion of gastrin
0.697 0.303 0.000
E16.3 Increased secretion of glucagon
0.697 0.303 0.000
N18.4 Chronic kidney disease, stage 4
0.696 0.304 0.000
M25.2 Flail joint
0.696 0.304 0.000
M25.1 Fistula of joint
0.696 0.304 0.000
M06.0 Seronegative rheumatoid arthritis
0.696 0.304 0.000
M93 Other osteochondropathies
0.696 0.304 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.695 0.305 0.000
E14.0 With coma
0.694 0.305 0.000
L44 Other papulosquamous disorders
0.694 0.306 0.000
E76 Disorders of glycosaminoglycan metabolism
0.694 0.306 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.694 0.306 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.694 0.306 0.000
N04.2 Diffuse membranous glomerulonephritis
0.694 0.306 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.693 0.307 0.000
E32 Diseases of thymus
0.693 0.307 0.000
E30 Disorders of puberty, not elsewhere classified
0.693 0.307 0.000
E78.4 Other hyperlipidaemia
0.693 0.307 0.000
M24.09 Loose body in joint (Site unspecified)
0.693 0.307 0.000
M24.08 Loose body in joint (Other)
0.693 0.307 0.000
M24.00 Loose body in joint (Multiple sites)
0.693 0.307 0.000
F34.1 Dysthymia
0.692 0.308 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.692 0.308 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.692 0.308 0.000
E14.6 With other specified complications
0.691 0.309 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.691 0.309 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.690 0.310 0.000
E40-E46 Malnutrition
0.689 0.311 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.689 0.311 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.687 0.313 0.000
N18.3 Chronic kidney disease, stage 3
0.686 0.314 0.000
D81 Combined immunodeficiencies
0.685 0.314 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.685 0.315 0.000
M07.38 Other psoriatic arthropathies (Other)
0.685 0.315 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.684 0.316 0.000
H65.3 Chronic mucoid otitis media
0.682 0.318 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.680 0.320 0.000
E51 Thiamine deficiency
0.680 0.320 0.000
E66.1 Drug-induced obesity
0.679 0.321 0.000
L10-L14 Bullous disorders
0.679 0.321 0.000
E70 Disorders of aromatic amino-acid metabolism
0.678 0.322 0.000
N03.8 Other
0.678 0.322 0.000
E77 Disorders of glycoprotein metabolism
0.678 0.322 0.000
D58 Other hereditary haemolytic anaemias
0.678 0.322 0.000
F60.9 Personality disorder, unspecified
0.677 0.323 0.000
M24.29 Disorder of ligament (Site unspecified)
0.677 0.323 0.000
M24.22 Disorder of ligament (Upper arm)
0.677 0.323 0.000
M24.20 Disorder of ligament (Multiple sites)
0.677 0.323 0.000
L43.3 Subacute (active) lichen planus
0.677 0.323 0.000
L43.2 Lichenoid drug reaction
0.677 0.323 0.000
L43.1 Bullous lichen planus
0.677 0.323 0.000
N03.1 Focal and segmental glomerular lesions
0.677 0.323 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.676 0.324 0.000
M25.98 Joint disorder, unspecified (Other)
0.676 0.324 0.000
E27.1 Primary adrenocortical insufficiency
0.676 0.324 0.000
F89 Unspecified disorder of psychological development
0.674 0.325 0.000
F88 Other disorders of psychological development
0.674 0.325 0.000
F83 Mixed specific developmental disorders
0.674 0.325 0.000
F82 Specific developmental disorder of motor function
0.674 0.325 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.674 0.326 0.000
F30.8 Other manic episodes
0.674 0.326 0.000
K90-K93 Other diseases of the digestive system
0.674 0.326 0.000
H36 Retinal disorders in diseases classified elsewhere
0.673 0.327 0.000
F30.2 Mania with psychotic symptoms
0.671 0.329 0.000
M34.8 Other forms of systemic sclerosis
0.670 0.330 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.669 0.330 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.669 0.331 0.000
F80.2 Receptive language disorder
0.669 0.331 0.000
F39 Unspecified mood [affective] disorder
0.668 0.331 0.000
F30.1 Mania without psychotic symptoms
0.668 0.332 0.000
M24.21 Disorder of ligament (Shoulder region)
0.668 0.332 0.000
E16.1 Other hypoglycaemia
0.668 0.332 0.000
E05.8 Other thyrotoxicosis
0.668 0.332 0.000
M25.43 Effusion of joint (Forearm)
0.666 0.334 0.000
M07.6 Other enteropathic arthropathies
0.666 0.334 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.665 0.335 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.665 0.335 0.000
M61 Calcification and ossification of muscle
0.665 0.335 0.000
E61.1 Iron deficiency
0.664 0.336 0.000
E31 Polyglandular dysfunction
0.664 0.336 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.663 0.337 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.662 0.338 0.000
H60.5 Acute otitis externa, non-infective
0.662 0.338 0.000
L41.1 Pityriasis lichenoides chronica
0.661 0.339 0.000
D83 Common variable immunodeficiency
0.661 0.339 0.000
M25.0 Haemarthrosis
0.661 0.339 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.660 0.340 0.000
M12 Other specific arthropathies
0.658 0.342 0.000
E29 Testicular dysfunction
0.657 0.343 0.000
M84 Disorders of continuity of bone
0.657 0.343 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.657 0.343 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.656 0.343 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.656 0.344 0.000
M05.0 Felty's syndrome
0.656 0.344 0.000
E84 Cystic fibrosis
0.655 0.344 0.000
E23.6 Other disorders of pituitary gland
0.655 0.345 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.654 0.346 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.653 0.347 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.653 0.347 0.000
E89.5 Postprocedural testicular hypofunction
0.653 0.347 0.000
E72 Other disorders of amino-acid metabolism
0.653 0.347 0.000
M34.9 Systemic sclerosis, unspecified
0.652 0.348 0.000
Chapter XI Diseases of the digestive system
0.652 0.348 0.000
F50 Eating disorders
0.652 0.348 0.000
E78.3 Hyperchylomicronaemia
0.651 0.348 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.651 0.349 0.000
M02 Reactive arthropathies
0.649 0.351 0.000
M14 Arthropathies in other diseases classified elsewhere
0.648 0.352 0.000
F31.7 Bipolar affective disorder, currently in remission
0.648 0.352 0.000
M60 Myositis
0.647 0.353 0.000
H60.9 Otitis externa, unspecified
0.647 0.353 0.000
E22.0 Acromegaly and pituitary gigantism
0.645 0.355 0.000
K70-K77 Diseases of liver
0.645 0.355 0.000
H71 Cholesteatoma of middle ear
0.644 0.356 0.000
M94 Other disorders of cartilage
0.643 0.356 0.000
K74 Fibrosis and cirrhosis of liver
0.643 0.357 0.000
E58 Dietary calcium deficiency
0.643 0.357 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.642 0.357 0.000
E85.9 Amyloidosis, unspecified
0.640 0.360 0.000
E34 Other endocrine disorders
0.639 0.360 0.000
L42 Pityriasis rosea
0.639 0.361 0.000
M06.4 Inflammatory polyarthropathy
0.639 0.361 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.639 0.361 0.000
D61.8 Other specified aplastic anaemias
0.638 0.362 0.000
D61.3 Idiopathic aplastic anaemia
0.638 0.362 0.000
D61.2 Aplastic anaemia due to other external agents
0.638 0.362 0.000
F60.5 Anankastic personality disorder
0.638 0.362 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.637 0.363 0.000
M62.0 Diastasis of muscle
0.637 0.363 0.000
E11.8 With unspecified complications
0.636 0.363 0.000
D73.5 Infarction of spleen
0.636 0.364 0.000
M25.3 Other instability of joint
0.635 0.365 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.635 0.365 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.635 0.365 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.634 0.366 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.633 0.366 0.000
F80.9 Developmental disorder of speech and language, unspecified
0.632 0.367 0.000
F80.8 Other developmental disorders of speech and language
0.632 0.367 0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]
0.632 0.367 0.000
F80.0 Specific speech articulation disorder
0.632 0.367 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.631 0.369 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.630 0.370 0.000
M62.4 Contracture of muscle
0.630 0.370 0.000
M62.3 Immobility syndrome (paraplegic)
0.630 0.370 0.000
M62.2 Ischaemic infarction of muscle
0.630 0.370 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.629 0.371 0.000
K74.3 Primary biliary cirrhosis
0.629 0.371 0.000
M11.2 Other chondrocalcinosis
0.628 0.372 0.000
D64.3 Other sideroblastic anaemias
0.628 0.372 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.627 0.373 0.000
E89.4 Postprocedural ovarian failure
0.627 0.373 0.000
M21 Other acquired deformities of limbs
0.627 0.373 0.000
E56 Other vitamin deficiencies
0.626 0.374 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.625 0.374 0.000
M62.6 Muscle strain
0.623 0.376 0.000
D74 Methaemoglobinaemia
0.623 0.377 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.623 0.377 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.623 0.377 0.000
D64.8 Other specified anaemias
0.623 0.377 0.000
D59 Acquired haemolytic anaemia
0.623 0.377 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.622 0.377 0.000
H60.2 Malignant otitis externa
0.622 0.378 0.000
E03 Other hypothyroidism
0.621 0.379 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.619 0.380 0.000
D73.8 Other diseases of spleen
0.619 0.381 0.000
E63 Other nutritional deficiencies
0.619 0.381 0.000
N18.9 Chronic renal failure, unspecified
0.619 0.381 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.618 0.382 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.618 0.382 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.616 0.384 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.616 0.384 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.614 0.386 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.612 0.388 0.000
M33.2 Polymyositis
0.612 0.388 0.000
E26.9 Hyperaldosteronism, unspecified
0.611 0.389 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.611 0.389 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.611 0.389 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.611 0.389 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.610 0.390 0.000
D55 Anaemia due to enzyme disorders
0.609 0.391 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.609 0.391 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.609 0.391 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.609 0.391 0.000
K72 Hepatic failure, not elsewhere classified
0.608 0.392 0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.608 0.392 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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