TreeWAS – Variant ID: rs2523587

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
G35 Multiple sclerosis	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
D69.6 Thrombocytopenia, unspecified	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
D69 Purpura and other haemorrhagic conditions	1.000	0.000	0.000
M35.0 Sicca syndrome [Sjogren]	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	1.000	0.000	0.000
E70-E90 Metabolic disorders	1.000	0.000	0.000
D80-D89 Certain disorders involving the immune mechanism	1.000	0.000	0.000
E83 Disorders of mineral metabolism	0.999	0.001	0.000
# Top node	0.999	0.001	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.001	0.999
M35 Other systemic involvement of connective tissue	0.998	0.002	0.000
M20-M25 Other joint disorders	0.998	0.002	0.000
K90 Intestinal malabsorption	0.998	0.002	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.995	0.005	0.000
D50-D53 Nutritional anaemias	0.994	0.006	0.000
E50-E64 Other nutritional deficiencies	0.994	0.006	0.000
Chapter VI Diseases of the nervous system	0.993	0.007	0.000
E10-E14 Diabetes mellitus	0.993	0.007	0.000
D86 Sarcoidosis	0.991	0.009	0.000
E89.0 Postprocedural hypothyroidism	0.990	0.010	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.990	0.010	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.012	0.988
E53 Deficiency of other B group vitamins	0.986	0.014	0.000
E10 Insulin-dependent diabetes mellitus	0.986	0.014	0.000
D86.9 Sarcoidosis, unspecified	0.984	0.016	0.000
E53.8 Deficiency of other specified B group vitamins	0.980	0.020	0.000
D50 Iron deficiency anaemia	0.978	0.022	0.000
K90-K93 Other diseases of the digestive system	0.973	0.027	0.000
Chapter XI Diseases of the digestive system	0.972	0.028	0.000
M21 Other acquired deformities of limbs	0.970	0.030	0.000
K70-K77 Diseases of liver	0.964	0.036	0.000
M60-M63 Disorders of muscles	0.960	0.040	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.958	0.042	0.000
M34 Systemic sclerosis	0.957	0.043	0.000
M21.0 Valgus deformity, not elsewhere classified	0.951	0.049	0.000
D50.9 Iron deficiency anaemia, unspecified	0.950	0.050	0.000
E10.2 With renal complications	0.947	0.053	0.000
E14 Unspecified diabetes mellitus	0.945	0.055	0.000
D80 Immunodeficiency with predominantly antibody defects	0.943	0.057	0.000
K70 Alcoholic liver disease	0.942	0.058	0.000
E06 Thyroiditis	0.942	0.058	0.000
E73 Lactose intolerance	0.939	0.061	0.000
E10.3 With ophthalmic complications	0.939	0.061	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.937	0.063	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.933	0.067	0.000
D51 Vitamin B12 deficiency anaemia	0.931	0.069	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.930	0.070	0.000
E14.3 With ophthalmic complications	0.930	0.070	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.924	0.076	0.000
K75 Other inflammatory liver diseases	0.922	0.078	0.000
K90.9 Intestinal malabsorption, unspecified	0.914	0.086	0.000
K70.9 Alcoholic liver disease, unspecified	0.912	0.088	0.000
K75.4 Autoimmune hepatitis	0.911	0.089	0.000
E06.3 Autoimmune thyroiditis	0.908	0.092	0.000
L40 Psoriasis	0.005	0.092	0.903
L50-L54 Urticaria and erythema	0.907	0.093	0.000
M21.8 Other specified acquired deformities of limbs	0.904	0.096	0.000
M62 Other disorders of muscle	0.904	0.096	0.000
E55 Vitamin D deficiency	0.903	0.097	0.000
M40-M43 Deforming dorsopathies	0.898	0.102	0.000
E73.9 Lactose intolerance, unspecified	0.895	0.105	0.000
D69.5 Secondary thrombocytopenia	0.890	0.110	0.000
M32 Systemic lupus erythematosus	0.888	0.112	0.000
M00-M03 Infectious arthropathies	0.888	0.112	0.000
R30-R39 Symptoms and signs involving the urinary system	0.000	0.115	0.885
K50-K52 Noninfective enteritis and colitis	0.885	0.115	0.000
L10-L14 Bullous disorders	0.884	0.116	0.000
E27.1 Primary adrenocortical insufficiency	0.879	0.121	0.000
G30-G32 Other degenerative diseases of the nervous system	0.878	0.122	0.000
K73 Chronic hepatitis, not elsewhere classified	0.877	0.123	0.000
E20-E35 Disorders of other endocrine glands	0.877	0.123	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.125	0.875
G80-G83 Cerebral palsy and other paralytic syndromes	0.873	0.127	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.872	0.128	0.000
E27 Other disorders of adrenal gland	0.871	0.129	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.870	0.130	0.000
K51 Ulcerative colitis	0.868	0.132	0.000
R35 Polyuria	0.000	0.134	0.866
E10.1 With ketoacidosis	0.862	0.138	0.000
D69.4 Other primary thrombocytopenia	0.861	0.139	0.000
M34.8 Other forms of systemic sclerosis	0.860	0.140	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.858	0.142	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.854	0.146	0.000
L50 Urticaria	0.853	0.147	0.000
L52 Erythema nodosum	0.852	0.148	0.000
M43 Other deforming dorsopathies	0.848	0.152	0.000
D69.2 Other nonthrombocytopenic purpura	0.848	0.152	0.000
M33 Dermatopolymyositis	0.847	0.153	0.000
E03.8 Other specified hypothyroidism	0.840	0.160	0.000
M60 Myositis	0.839	0.161	0.000
E55.9 Vitamin D deficiency, unspecified	0.839	0.161	0.000
L40.5 Arthropathic psoriasis	0.000	0.165	0.835
E83.5 Disorders of calcium metabolism	0.835	0.165	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.834	0.166	0.000
R30 Pain associated with micturition	0.000	0.170	0.830
M45 Ankylosing spondylitis	0.007	0.171	0.822
D69.8 Other specified haemorrhagic conditions	0.825	0.175	0.000
M34.9 Systemic sclerosis, unspecified	0.823	0.177	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.822	0.178	0.000
L13 Other bullous disorders	0.820	0.180	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.819	0.181	0.000
M62.8 Other specified disorders of muscle	0.818	0.182	0.000
K70.4 Alcoholic hepatic failure	0.814	0.186	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.814	0.186	0.000
M43.0 Spondylolysis	0.813	0.187	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.810	0.190	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.810	0.190	0.000
R30.0 Dysuria	0.000	0.193	0.807
M00 Pyogenic arthritis	0.804	0.196	0.000
D50.1 Sideropenic dysphagia	0.803	0.197	0.000
L40.8 Other psoriasis	0.002	0.199	0.799
R39 Other symptoms and signs involving the urinary system	0.000	0.200	0.800
E10.7 With multiple complications	0.795	0.205	0.000
K51.8 Other ulcerative colitis	0.794	0.206	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.791	0.209	0.000
M43.02 Spondylolysis (Cervical region)	0.791	0.209	0.000
D60-D64 Aplastic and other anaemias	0.791	0.209	0.000
G81 Hemiplegia	0.789	0.210	0.000
D86.3 Sarcoidosis of skin	0.785	0.215	0.000
E10.9 Without complications	0.785	0.215	0.000
Chapter I Certain infectious and parasitic diseases	0.784	0.216	0.000
E14.8 With unspecified complications	0.783	0.217	0.000
D55-D59 Haemolytic anaemias	0.782	0.218	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.782	0.218	0.000
L50.9 Urticaria, unspecified	0.782	0.218	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.000	0.220	0.780
M34.0 Progressive systemic sclerosis	0.780	0.220	0.000
G00 Bacterial meningitis, not elsewhere classified	0.780	0.220	0.000
K90.8 Other intestinal malabsorption	0.778	0.222	0.000
K51.4 Pseudopolyposis of colon	0.778	0.222	0.000
L20-L30 Dermatitis and eczema	0.778	0.222	0.000
K72 Hepatic failure, not elsewhere classified	0.777	0.223	0.000
L13.0 Dermatitis herpetiformis	0.775	0.225	0.000
E53.9 Vitamin B deficiency, unspecified	0.775	0.225	0.000
M35.7 Hypermobility syndrome	0.770	0.230	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.767	0.233	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.766	0.234	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.765	0.235	0.000
D61 Other aplastic anaemias	0.761	0.239	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.759	0.241	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.758	0.242	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.757	0.243	0.000
D66 Hereditary factor VIII deficiency	0.756	0.244	0.000
D83 Common variable immunodeficiency	0.754	0.245	0.000
M86-M90 Other osteopathies	0.753	0.247	0.000
D86.1 Sarcoidosis of lymph nodes	0.752	0.248	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.751	0.249	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.751	0.249	0.000
K73.9 Chronic hepatitis, unspecified	0.750	0.250	0.000
E20 Hypoparathyroidism	0.747	0.253	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.747	0.253	0.000
M33.1 Other dermatomyositis	0.747	0.253	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.746	0.254	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.745	0.255	0.000
E14.2 Withrenal complications	0.745	0.255	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.745	0.255	0.000
D61.9 Aplastic anaemia, unspecified	0.744	0.256	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.743	0.257	0.000
E51 Thiamine deficiency	0.743	0.257	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.742	0.258	0.000
D86.0 Sarcoidosis of lung	0.741	0.259	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.738	0.262	0.000
M60.9 Myositis, unspecified	0.737	0.263	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.735	0.265	0.000
G81.9 Hemiplegia, unspecified	0.734	0.266	0.000
B25-B34 Other viral diseases	0.734	0.266	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.732	0.268	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.730	0.270	0.000
L11 Other acantholytic disorders	0.729	0.271	0.000
E88 Other metabolic disorders	0.725	0.275	0.000
M23 Internal derangement of knee	0.725	0.275	0.000
E31 Polyglandular dysfunction	0.722	0.278	0.000
M62.2 Ischaemic infarction of muscle	0.721	0.279	0.000
E05.8 Other thyrotoxicosis	0.720	0.280	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
D67 Hereditary factor IX deficiency	0.717	0.283	0.000
E77 Disorders of glycoprotein metabolism	0.717	0.283	0.000
E76 Disorders of glycosaminoglycan metabolism	0.717	0.283	0.000
E72 Other disorders of amino-acid metabolism	0.717	0.283	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.717	0.283	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.717	0.283	0.000
D81 Combined immunodeficiencies	0.717	0.283	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.717	0.283	0.000
E83.8 Other disorders of mineral metabolism	0.717	0.283	0.000
E83.2 Disorders of zinc metabolism	0.717	0.283	0.000
E83.0 Disorders of copper metabolism	0.717	0.283	0.000
B07 Viral warts	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284	0.000
B25 Cytomegaloviral disease	0.716	0.284	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.716	0.284	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.716	0.284	0.000
M35.5 Multifocal fibrosclerosis	0.716	0.284	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.716	0.284	0.000
K90.3 Pancreatic steatorrhoea	0.716	0.284	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.716	0.284	0.000
K90.1 Tropical sprue	0.716	0.284	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.715	0.285	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.714	0.285	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.003	0.286	0.711
M22 Disorders of patella	0.714	0.286	0.000
K72.0 Acute and subacute hepatic failure	0.713	0.287	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.712	0.288	0.000
E63 Other nutritional deficiencies	0.712	0.288	0.000
E50 Vitamin A deficiency	0.712	0.288	0.000
E60 Dietary zinc deficiency	0.712	0.288	0.000
E59 Dietary selenium deficiency	0.712	0.288	0.000
E54 Ascorbic acid deficiency	0.712	0.288	0.000
E52 Niacin deficiency [pellagra]	0.712	0.288	0.000
E12 Malnutrition-related diabetes mellitus	0.712	0.288	0.000
D84 Other immunodeficiencies	0.711	0.289	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.710	0.290	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.710	0.290	0.000
E89.5 Postprocedural testicular hypofunction	0.710	0.290	0.000
E89.1 Postprocedural hypoinsulinaemia	0.710	0.290	0.000
M35.8 Other specified systemic involvement of connective tissue	0.710	0.290	0.000
G31.2 Degeneration of nervous system due to alcohol	0.710	0.290	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.708	0.292	0.000
E53.1 Pyridoxine deficiency	0.707	0.293	0.000
E53.0 Riboflavin deficiency	0.707	0.293	0.000
L50.1 Idiopathic urticaria	0.706	0.293	0.000
M34.1 CR(E)ST syndrome	0.706	0.294	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.706	0.294	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.003	0.295	0.702
L53 Other erythematous conditions	0.705	0.295	0.000
E70 Disorders of aromatic amino-acid metabolism	0.704	0.296	0.000
E27.2 Addisonian crisis	0.703	0.297	0.000
D53 Other nutritional anaemias	0.703	0.297	0.000
L40-L45 Papulosquamous disorders	0.171	0.298	0.531
D59 Acquired haemolytic anaemia	0.701	0.299	0.000
M30 Polyarteritis nodosa and related conditions	0.700	0.299	0.000
K75.8 Other specified inflammatory liver diseases	0.700	0.300	0.000
B25.9 Cytomegaloviral disease, unspecified	0.699	0.301	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.697	0.303	0.000
E03.1 Congenital hypothyroidism without goitre	0.697	0.303	0.000
D89.1 Cryoglobulinaemia	0.697	0.303	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.697	0.303	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.696	0.304	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.695	0.305	0.000
M35.1 Other overlap syndromes	0.694	0.305	0.000
M00.9 Pyogenic arthritis, unspecified	0.694	0.306	0.000
E84 Cystic fibrosis	0.691	0.308	0.000
K77 Liver disorders in diseases classified elsewhere	0.691	0.309	0.000
M21.7 Unequal limb length (acquired)	0.691	0.309	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.689	0.311	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.689	0.311	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.688	0.311	0.000
M61 Calcification and ossification of muscle	0.688	0.311	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.688	0.312	0.000
L21 Seborrhoeic dermatitis	0.687	0.312	0.000
D89.3 Immune reconstitution syndrome	0.687	0.313	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.686	0.314	0.000
R34 Anuria and oliguria	0.000	0.314	0.686
M62.80 Other specified disorders of muscle (Multiple sites)	0.685	0.315	0.000
G36 Other acute disseminated demyelination	0.685	0.315	0.000
M23.4 Loose body in knee	0.685	0.315	0.000
E14.5 With peripheral circulatory complications	0.684	0.315	0.000
L12 Pemphigoid	0.684	0.316	0.000
E14.6 With other specified complications	0.683	0.316	0.000
D52 Folate deficiency anaemia	0.683	0.317	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.682	0.318	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.682	0.318	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.682	0.318	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.682	0.318	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.682	0.318	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.682	0.318	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.682	0.318	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.682	0.318	0.000
G82 Paraplegia and tetraplegia	0.681	0.319	0.000
M21.9 Acquired deformity of limb, unspecified	0.679	0.321	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.679	0.321	0.000
E10.8 With unspecified complications	0.678	0.321	0.000
E07 Other disorders of thyroid	0.677	0.323	0.000
E14.7 With multiple complications	0.677	0.323	0.000
E14.0 With coma	0.677	0.323	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.676	0.324	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.676	0.324	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.676	0.324	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.676	0.324	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.676	0.324	0.000
E06.5 Other chronic thyroiditis	0.675	0.324	0.000
E06.4 Drug-induced thyroiditis	0.675	0.324	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.675	0.324	0.000
E06.1 Subacute thyroiditis	0.675	0.324	0.000
E06.0 Acute thyroiditis	0.675	0.324	0.000
M40 Kyphosis and lordosis	0.674	0.326	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.674	0.326	0.000
E73.8 Other lactose intolerance	0.673	0.327	0.000
E73.1 Secondary lactase deficiency	0.673	0.327	0.000
E73.0 Congenital lactase deficiency	0.673	0.327	0.000
M62.0 Diastasis of muscle	0.673	0.327	0.000
E56 Other vitamin deficiencies	0.672	0.328	0.000
L50.0 Allergic urticaria	0.672	0.328	0.000
M62.9 Disorder of muscle, unspecified	0.671	0.329	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.667	0.333	0.000
D51.2 Transcobalamin II deficiency	0.667	0.333	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.667	0.333	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.667	0.333	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.666	0.333	0.000
M24 Other specific joint derangements	0.666	0.334	0.000
M23.49 Loose body in knee-Unspec lig/men	0.666	0.334	0.000
M62.6 Muscle strain	0.664	0.336	0.000
M43.9 Deforming dorsopathy, unspecified	0.664	0.336	0.000
M21.6 Other acquired deformities of ankle and foot	0.663	0.337	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.663	0.337	0.000
D69.1 Qualitative platelet defects	0.663	0.337	0.000
K75.2 Nonspecific reactive hepatitis	0.661	0.339	0.000
K75.1 Phlebitis of portal vein	0.661	0.339	0.000
M31 Other necrotising vasculopathies	0.661	0.339	0.000
G00.9 Bacterial meningitis, unspecified	0.660	0.339	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.658	0.341	0.000
M02 Reactive arthropathies	0.658	0.342	0.000
K51.5 Mucosal proctocolitis	0.657	0.343	0.000
G31.0 Circumscribed brain atrophy	0.655	0.345	0.000
E20.9 Hypoparathyroidism, unspecified	0.654	0.346	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.651	0.348	0.000
M22.2 Patellofemoral disorders	0.652	0.348	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.651	0.349	0.000
L40.4 Guttate psoriasis	0.004	0.349	0.647
L40.2 Acrodermatitis continua	0.004	0.349	0.647
M21.83 Other specified acquired deformities of limbs (Forearm)	0.651	0.349	0.000
L54 Erythema in diseases classified elsewhere	0.651	0.349	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.648	0.352	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.648	0.352	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.648	0.352	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.648	0.352	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.648	0.352	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.648	0.352	0.000
M62.4 Contracture of muscle	0.648	0.352	0.000
M62.3 Immobility syndrome (paraplegic)	0.648	0.352	0.000
E55.0 Rickets, active	0.648	0.352	0.000
M42 Spinal osteochondrosis	0.644	0.356	0.000
M60.99 Myositis, unspecified (Site unspecified)	0.644	0.356	0.000
E58 Dietary calcium deficiency	0.643	0.357	0.000
K70.3 Alcoholic cirrhosis of liver	0.642	0.358	0.000
D50.8 Other iron deficiency anaemias	0.641	0.359	0.000
K70.0 Alcoholic fatty liver	0.640	0.360	0.000
L27 Dermatitis due to substances taken internally	0.639	0.361	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.639	0.361	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.638	0.362	0.000
E13 Other specified diabetes mellitus	0.637	0.363	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.637	0.363	0.000
M32.8 Other forms of systemic lupus erythematosus	0.637	0.363	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.637	0.363	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.637	0.363	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.637	0.363	0.000
D82 Immunodeficiency associated with other major defects	0.636	0.364	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.635	0.365	0.000
M43.8 Other specified deforming dorsopathies	0.634	0.366	0.000
L14 Bullous disorders in diseases classified elsewhere	0.634	0.366	0.000
E89.4 Postprocedural ovarian failure	0.634	0.366	0.000
K71 Toxic liver disease	0.634	0.366	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.633	0.367	0.000
K70.1 Alcoholic hepatitis	0.633	0.367	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.633	0.367	0.000
E10.0 With coma	0.631	0.369	0.000
G80 Infantile cerebral palsy	0.630	0.370	0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified	0.630	0.370	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.629	0.371	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.629	0.371	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.628	0.371	0.000
E32 Diseases of thymus	0.628	0.371	0.000
E30 Disorders of puberty, not elsewhere classified	0.628	0.371	0.000
E79 Disorders of purine and pyrimidine metabolism	0.628	0.372	0.000
L10 Pemphigus	0.627	0.373	0.000
E27.5 Adrenomedullary hyperfunction	0.625	0.375	0.000
E27.0 Other adrenocortical overactivity	0.625	0.375	0.000
G00.2 Streptococcal meningitis	0.624	0.376	0.000
E10.6 With other specified complications	0.624	0.376	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.624	0.376	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.623	0.377	0.000
E25 Adrenogenital disorders	0.622	0.378	0.000
E10.5 With peripheral circulatory complications	0.622	0.378	0.000
K52 Other non-infective gastro-enteritis and colitis	0.621	0.379	0.000
G37 Other demyelinating diseases of central nervous system	0.620	0.380	0.000
G70-G73 Diseases of myoneural junction and muscle	0.620	0.380	0.000
G82.1 Spastic paraplegia	0.618	0.382	0.000
E06.9 Thyroiditis, unspecified	0.618	0.382	0.000
E14.1 With ketoacidosis	0.616	0.383	0.000
L26 Exfoliative dermatitis	0.616	0.384	0.000
E74 Other disorders of carbohydrate metabolism	0.615	0.385	0.000
E14.4 With neurological complications	0.614	0.386	0.000
L28 Lichen simplex chronicus and prurigo	0.614	0.386	0.000
M23.5 Chronic instability of knee	0.614	0.386	0.000
E88.8 Other specified metabolic disorders	0.613	0.387	0.000
E31.0 Autoimmune polyglandular failure	0.612	0.388	0.000
L50.6 Contact urticaria	0.612	0.388	0.000
L50.5 Cholinergic urticaria	0.612	0.388	0.000
L50.4 Vibratory urticaria	0.612	0.388	0.000
L50.3 Dermatographic urticaria	0.612	0.388	0.000
L50.2 Urticaria due to cold and heat	0.612	0.388	0.000
R30.1 Vesical tenesmus	0.000	0.389	0.611
M89 Other disorders of bone	0.610	0.390	0.000
G00.1 Pneumococcal meningitis	0.609	0.390	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.609	0.391	0.000
M60.0 Infective myositis	0.609	0.391	0.000
M43.5 Other recurrent vertebral subluxation	0.608	0.392	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.608	0.392	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.608	0.392	0.000
M33.9 Dermatopolymyositis, unspecified	0.607	0.393	0.000
M33.0 Juvenile dermatomyositis	0.607	0.393	0.000
M43.2 Other fusion of spine	0.607	0.393	0.000
L53.8 Other specified erythematous conditions	0.607	0.393	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.606	0.394	0.000
B01 Varicella [chickenpox]	0.606	0.394	0.000
M21.4 Flat foot [pes planus] (acquired)	0.605	0.394	0.000
B35-B49 Mycoses	0.605	0.395	0.000
M60.8 Other myositis	0.604	0.396	0.000
G11 Hereditary ataxia	0.603	0.397	0.000
M86 Osteomyelitis	0.603	0.397	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.603	0.397	0.000
M23.1 Discoid meniscus (congenital)	0.602	0.398	0.000
M43.6 Torticollis	0.602	0.398	0.000
M60.1 Interstitial myositis	0.602	0.398	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.600	0.400	0.000
K75.0 Abscess of liver	0.599	0.400	0.000
L11.0 Acquired keratosis follicularis	0.599	0.401	0.000
L20 Atopic dermatitis	0.599	0.401	0.000
M43.06 Spondylolysis (Lumbar region)	0.599	0.401	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.598	0.402	0.000
B27 Infectious mononucleosis	0.597	0.403	0.000
M24.5 Contracture of joint	0.597	0.403	0.000
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.596	0.403	0.000
M21.2 Flexion deformity	0.596	0.404	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.596	0.404	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.596	0.404	0.000
L40.1 Generalised pustular psoriasis	0.004	0.404	0.592
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.005	0.406	0.589
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.005	0.406	0.589
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.005	0.406	0.589
M45.X4 Ankylosing spondylitis (Thoracic region)	0.005	0.406	0.589
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.005	0.406	0.589
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.005	0.406	0.589
M23.9 Internal derangement of knee, unspecified	0.593	0.407	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.592	0.408	0.000
E40-E46 Malnutrition	0.592	0.408	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.591	0.409	0.000
E10.4 With neurological complications	0.590	0.410	0.000
M62.26 Ischaemic infarction of muscle (Lower leg)	0.590	0.410	0.000
Chapter XXII Codes for special purposes	0.590	0.410	0.000
L13.9 Bullous disorder, unspecified	0.588	0.412	0.000
L13.8 Other specified bullous disorders	0.588	0.412	0.000
L13.1 Subcorneal pustular dermatitis	0.588	0.412	0.000
M33.2 Polymyositis	0.587	0.413	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.587	0.413	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.587	0.413	0.000
M62.84 Other specified disorders of muscle (Hand)	0.587	0.413	0.000
E28 Ovarian dysfunction	0.583	0.416	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.583	0.417	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.583	0.417	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.583	0.417	0.000
M43.04 Spondylolysis (Thoracic region)	0.583	0.417	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.583	0.417	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.583	0.417	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.583	0.417	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.005	0.418	0.577
A50-A64 Infections with a predominantly sexual mode of transmission	0.581	0.419	0.000
R39.0 Extravasation of urine	0.000	0.419	0.581
B25.0 Cytomegaloviral pneumonitis	0.580	0.420	0.000
E07.8 Other specified disorders of thyroid	0.580	0.420	0.000
D83.9 Common variable immunodeficiency, unspecified	0.579	0.421	0.000
L53.0 Toxic erythema	0.579	0.421	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.578	0.422	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.576	0.424	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.576	0.424	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.576	0.424	0.000
R39.2 Extrarenal uraemia	0.000	0.427	0.573
M60.95 Myositis, unspecified (Pelvic region and thigh)	0.573	0.427	0.000
D86.8 Sarcoidosis of other and combined sites	0.570	0.430	0.000
M65-M68 Disorders of synovium and tendon	0.569	0.431	0.000
L50.8 Other urticaria	0.568	0.431	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.567	0.433	0.000
D58 Other hereditary haemolytic anaemias	0.567	0.433	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.566	0.434	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.566	0.434	0.000
G81.0 Flaccid hemiplegia	0.566	0.434	0.000
Chapter V Mental and behavioural disorders	0.566	0.434	0.000
D69.9 Haemorrhagic condition, unspecified	0.564	0.435	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.564	0.436	0.000
L25 Unspecified contact dermatitis	0.564	0.436	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations